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Mining the rumen for fibrolytic feed enzymes 从瘤胃中提取纤维分解饲料酶
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-04-01 DOI: 10.2527/AF.2016-0019
G. Ribeiro, R. Gruninger, A. Badhan, T. McAllister
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引用次数: 55
The nasopharyngeal microbiota in feedlot cattle and its role in respiratory health 饲养场牛鼻咽微生物群及其在呼吸系统健康中的作用
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-04-01 DOI: 10.2527/AF.2016-0022
E. Timsit, D. Holman, J. Hallewell, T. Alexander
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引用次数: 48
Effects of grain feeding on microbiota in the digestive tract of cattle 谷物饲喂对牛消化道微生物群的影响
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-04-01 DOI: 10.2527/AF.2016-0018
E. Khafipour, S. Li, H. Tun, H. Derakhshani, S. Moossavi, J. Plaizier
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引用次数: 86
Genomic selection in commercial pig breeding 商品猪育种中的基因组选择
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/AF.2016-0003
E. Knol, B. Nielsen, P. Knap
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引用次数: 102
American Society of Animal Science News 美国动物科学学会新闻
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/af.2016-0014
J. Doe
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引用次数: 0
Canadian Society of Animal Science News 加拿大动物科学协会新闻
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/af.2016-0025
J. Doe
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引用次数: 0
Genomic applications in horse breeding 基因组学在马育种中的应用
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/AF.2016-0007
K. Stock, L. Jönsson, A. Ricard, T. Mark
The aim of this paper is to review the framework of equine genomic research and innovation and the implementation status of genomic applications for different groups of traits and populations as well as their pro-spective development in horse breeding. Potential implications for future horse breeding schemes will be discussed, with a focus on sport horses.
本文综述了马基因组学研究与创新的框架、不同性状群体和种群基因组学应用的实施现状及其在马育种中的发展前景。对未来马匹育种计划的潜在影响将被讨论,重点是运动马。
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引用次数: 12
Metabolomics and livestock genomics: Insights into a phenotyping frontier and its applications in animal breeding 代谢组学和家畜基因组学:表型前沿及其在动物育种中的应用
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/AF.2016-0011
L. Fontanesi
Implications Metabolomics is the emerging field of metabolome analysis that identify, quantify, and characterize a large number of metabolites in biological samples (e.g., milk, plasma, and serum), providing interesting insights into the so called intermediate phenotypes that lie in the middle between the genomic space (or level) and the final or external phenotypes, that in livestock might be production traits such as growth rate, milk production, fat deposition, and other economic relevant traits. • Metabolomics applied to animal breeding might become a cornerstone of the “next generation phenotyping” approaches that are needed to refine and improve trait description and, in turn, to improve prediction of the breeding values of the animals to cope with traditional and new objectives of the selection programs. • Integration of metabolomics with livestock genomics has been presented in just few studies with promising perspectives. • Genome-wide association studies with metabotypes (mGWAS) described thus far in cattle and pigs have linked genomic variability with metabotype levels in relevant biofluids. • Network reconstruction methodologies based on systems genetics concepts have been applied to disentangle the complexity of metabolomics information and linking metabolomics with other omics data. • New and conventional traits and related genetic architecture could be better defined using metabotypes opening opportunities for novel applications in animal breeding.
代谢组学是代谢组学分析的新兴领域,它识别、量化和表征生物样本(如牛奶、血浆和血清)中的大量代谢物,为所谓的中间表型提供有趣的见解,这些中间表型位于基因组空间(或水平)和最终或外部表型之间,在牲畜中可能是生产性状,如生长速度、产奶量、脂肪沉积、以及其他与经济相关的特征。•代谢组学应用于动物育种可能成为“下一代表型”方法的基石,这些方法需要完善和改进性状描述,反过来,提高动物育种价值的预测,以应对传统和新的选择计划目标。•代谢组学与牲畜基因组学的整合仅在少数具有前景的研究中提出。•迄今在牛和猪中描述的与代谢型(mGWAS)的全基因组关联研究已将基因组变异性与相关生物体液中的代谢型水平联系起来。•基于系统遗传学概念的网络重建方法已被应用于解开代谢组学信息的复杂性,并将代谢组学与其他组学数据联系起来。•利用代谢型可以更好地定义新的和传统的性状以及相关的遗传结构,为动物育种中的新应用提供了机会。
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引用次数: 53
From the Editors: Animal breeding in the genomics era 编辑:基因组学时代的动物育种
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/AF.2016-0001
N. Ibáñez-Escriche, H. Simianer
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引用次数: 9
Genomic selection: A paradigm shift in animal breeding 基因组选择:动物育种的范式转变
IF 3.6 2区 农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE Pub Date : 2016-01-01 DOI: 10.2527/AF.2016-0002
T. Meuwissen, B. Hayes, M. Goddard
• Traditional marker-assisted selection (MAS) did not result in a widespread use of DNA information in animal breeding. The main reason was that the traits of interest in livestock production were much more complex than expected: they were determined by thousands of genes with small effects on phenotype. These effects were usually too small to be statistically significant and so were ignored. • Genomic selection (GS) assumes that all markers might be linked to a gene affecting the trait and concentrates on estimating their effect rather than testing its significance. Three technological breakthroughs resulted in the current wide-spread use of DNA information in animal breeding: the development of the genomic selection technology, the discovery of massive numbers of genetic markers (single nucleotide polymorphisms; SNPs), and high-throughput technology to genotype animals for (hundreds of) thousands of SNPs in a cost-effective manner. • Here we review current methods for GS, including how they deal with practical data, where genotypes are missing on a large scale. The use of whole-genome sequence data is anticipated, and its advantages and disadvantages are depicted. Current and predicted future impacts of GS on dairy and beef cattle, pigs, and poultry breeding are described. Finally, future directions for GS are discussed. • It is anticipated that future GS applications will either be: within breed (wbGS), where accuracy is obtained by maintaining huge withinbreed reference populations; or across breed (abGS) where accuracy is obtained from across-breed reference populations and high-density GS methods that focus on causative genomic regions. We argue that future GS applications will increasingly turn toward abGS.
•传统的标记辅助选择(MAS)并没有导致DNA信息在动物育种中的广泛使用。主要原因是畜牧生产中感兴趣的性状比预期的要复杂得多:它们是由数千个基因决定的,对表型的影响很小。这些影响通常太小而不具有统计学意义,因此被忽略。•基因组选择(GS)假设所有标记都可能与影响性状的基因有关,并集中于估计它们的影响,而不是测试其重要性。三个技术突破导致了DNA信息在动物育种中的广泛应用:基因组选择技术的发展,大量遗传标记(单核苷酸多态性)的发现;以及高通量技术,以经济有效的方式对动物进行(数十万)个SNPs的基因分型。•在这里,我们回顾了当前的GS方法,包括它们如何处理大量缺失基因型的实际数据。全基因组序列数据的使用是预期的,其优点和缺点进行了描述。描述了GS对奶牛和肉牛、猪和家禽育种的当前和预测的未来影响。最后,对未来的发展方向进行了展望。•预计未来的GS应用将会是:品种内(wbGS),通过保持大量品种内参考种群来获得准确性;或跨品种(abGS),其中准确性来自跨品种参考群体和高密度GS方法,重点关注致病基因组区域。我们认为,未来的GS应用将越来越多地转向abGS。
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引用次数: 315
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Animal Frontiers
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