Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.092
Ruchi Rastogi, Gunmala Bhatnagar, D. Kalita
Mature cystic teratomas of ovary are common benign germ cell tumors that constitute about 20% of all the ovarian tumors. These tumors however have a rare potential for malignant transformation 0.17-2% and therefore there is a requirement for intraoperative diagnosis to establish an appropriate line of treatment. Incidence of mature cystic teratoma undergoing multiple types of malignant transformation in the same patient is extremely rare and only a small number of such cases have been published in literature. Histopathology and immunohistochemistry are the gold standard for diagnosis and remains the mainstay for defining the treatment course and prognosis.
{"title":"A curious case of benign ovarian teratoma with multiple malignant tranformations: A histopathologists quagmire","authors":"Ruchi Rastogi, Gunmala Bhatnagar, D. Kalita","doi":"10.18231/j.ijpo.2023.092","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.092","url":null,"abstract":"Mature cystic teratomas of ovary are common benign germ cell tumors that constitute about 20% of all the ovarian tumors. These tumors however have a rare potential for malignant transformation 0.17-2% and therefore there is a requirement for intraoperative diagnosis to establish an appropriate line of treatment. Incidence of mature cystic teratoma undergoing multiple types of malignant transformation in the same patient is extremely rare and only a small number of such cases have been published in literature. Histopathology and immunohistochemistry are the gold standard for diagnosis and remains the mainstay for defining the treatment course and prognosis.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.086
Aneesha Asok, Akhil Chandran M, Jayalakshmy P. S, Nisha T. G
Acute appendicitis is the most common disease of appendix. Here we are introducing 6 rare lesions of appendix from a tertiary care centre North Kerala. These incidental findings reveals the importance of extensive sampling of appendicectomy specimens.
{"title":"Rare pathological lesions of appendix – A case series","authors":"Aneesha Asok, Akhil Chandran M, Jayalakshmy P. S, Nisha T. G","doi":"10.18231/j.ijpo.2023.086","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.086","url":null,"abstract":"Acute appendicitis is the most common disease of appendix. Here we are introducing 6 rare lesions of appendix from a tertiary care centre North Kerala. These incidental findings reveals the importance of extensive sampling of appendicectomy specimens.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"39 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.087
Nikhil Sanjay Deshpande, Anil B. Munemane, R. Karle
We report a rare case of a pleomorphic adenoma with lipometaplasia. A 32-year-old woman presented with intraoral swelling over right side of palate. Computed tomography revealed a heterogeneously enhancing right hard palatal mass without bony erosions. Preoperative diagnosis was offered with intraoral fine needle aspiration cytology following which excision was performed. On histopatholgy, final diagnosis of pleomorphic adenoma with lipometaplasia offered. Though rare it must be kept in mind as differential in cases of fat containing salivary gland lesions.
{"title":"Pleomorphic adenoma with lipometaplasia: Rare histology finding of a common entity","authors":"Nikhil Sanjay Deshpande, Anil B. Munemane, R. Karle","doi":"10.18231/j.ijpo.2023.087","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.087","url":null,"abstract":"We report a rare case of a pleomorphic adenoma with lipometaplasia. A 32-year-old woman presented with intraoral swelling over right side of palate. Computed tomography revealed a heterogeneously enhancing right hard palatal mass without bony erosions. Preoperative diagnosis was offered with intraoral fine needle aspiration cytology following which excision was performed. On histopatholgy, final diagnosis of pleomorphic adenoma with lipometaplasia offered. Though rare it must be kept in mind as differential in cases of fat containing salivary gland lesions.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"6 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139000891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.090
S. Usman, Avadh Vihari Lal Sharma, Veena Maheshwari, Murad Ahmad, Zeeshan Nahid
Plexiform fibrohistiocytic tumor is a very rare tumor of soft tissue that affects usually adolescents and children. On histopathological examination it shows multiple small nodules or fascicles that are arranged in plexiform pattern, hence its name. Here we are presenting a case of occurrence of PFT in bilateral elbows. Patient presented with gradually increasing in size and painless swellings for 7 years. Excision was done and on the basis of histopathological and immunohistochemical examination diagnosis of PFT was reached.
{"title":"Plexiform fibrohistiocytic tumor of elbow: A rare case report","authors":"S. Usman, Avadh Vihari Lal Sharma, Veena Maheshwari, Murad Ahmad, Zeeshan Nahid","doi":"10.18231/j.ijpo.2023.090","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.090","url":null,"abstract":"Plexiform fibrohistiocytic tumor is a very rare tumor of soft tissue that affects usually adolescents and children. On histopathological examination it shows multiple small nodules or fascicles that are arranged in plexiform pattern, hence its name. Here we are presenting a case of occurrence of PFT in bilateral elbows. Patient presented with gradually increasing in size and painless swellings for 7 years. Excision was done and on the basis of histopathological and immunohistochemical examination diagnosis of PFT was reached.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"4 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139001063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.089
Richa Bhartiya, Sujata Agrawal, Poornakala S, Nina G Desai
Chronic eosinophilic leukemia (CEL) is a rare type of leukemia which is characterized by persistently increased number of eosinophils in peripheral blood and bone-marrow alongwith evidence of clonal proliferation of eosinophils with tissue infiltration by eosinophils leading to organ damage and causing systemic manifestations. An accurate diagnosis of CEL is essential as these patients show excellent response to imatinib mesylate. Use of technique like FISH (fluorescent in-situ hybridization) & RTPCR (Reverse Transcriptase) helps in proving the clonality of eosinophils. We report a case of CEL with FIP1L1 (Fip1-Like-1) PDGFRA (Platelet Derived Growth Factor Receptor – Alpha Gene) mutation in 29-year old male presenting with persistent eosinophilia. Rarity of this entity definitely needs a space in literature.
慢性嗜酸性粒细胞白血病（CEL）是一种罕见的白血病，其特征是外周血和骨髓中嗜酸性粒细胞数量持续增加，并伴有嗜酸性粒细胞克隆性增殖的证据，嗜酸性粒细胞对组织的浸润导致器官损伤并引起全身表现。准确诊断 CEL 至关重要，因为这些患者对甲磺酸伊马替尼的反应极佳。使用 FISH（荧光原位杂交）和 RTPCR（逆转录酶）等技术有助于证明嗜酸性粒细胞的克隆性。我们报告了一例 FIP1L1（Fip1-Like-1）PDGFRA（血小板生长因子受体-α基因）突变的 CEL 病例，患者为 29 岁男性，表现为持续性嗜酸性粒细胞增多。这种罕见的病例无疑需要在文献中占有一席之地。
{"title":"FIP1L1– PDGFRA positive chronic eosinophilic leukemia: A case report","authors":"Richa Bhartiya, Sujata Agrawal, Poornakala S, Nina G Desai","doi":"10.18231/j.ijpo.2023.089","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.089","url":null,"abstract":"Chronic eosinophilic leukemia (CEL) is a rare type of leukemia which is characterized by persistently increased number of eosinophils in peripheral blood and bone-marrow alongwith evidence of clonal proliferation of eosinophils with tissue infiltration by eosinophils leading to organ damage and causing systemic manifestations. An accurate diagnosis of CEL is essential as these patients show excellent response to imatinib mesylate. Use of technique like FISH (fluorescent in-situ hybridization) & RTPCR (Reverse Transcriptase) helps in proving the clonality of eosinophils. We report a case of CEL with FIP1L1 (Fip1-Like-1) PDGFRA (Platelet Derived Growth Factor Receptor – Alpha Gene) mutation in 29-year old male presenting with persistent eosinophilia. Rarity of this entity definitely needs a space in literature.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"305 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.077
T. Thapa, B. R. Bhattarai, S. Maharjan, Sushant Pokhrel, M. Sapkota
: Early and accurate diagnosis of dengue is critical for prompt treatment and avoiding severe complications. Thus, the present study aimed to evaluate the serological and hematological parameters for predicting the dengue virus infection. : A laboratory-based cross-sectional study was conducted among the patients who visited Sumeru Hospital, Lalitpur, Nepal, from July 2022 to June 2023. Blood samples were collected from suspected dengue cases and tested using the rapid diagnostic immunochromatography (ICT) method, and hematological parameters were also assessed. The Mann-Whitney U test compared continuous variables between dengue-infected and non-infected groups. A binary logistic regression analysis was done to evaluate the association of variables for dengue positivity.: When compared to dengue-negative cases, dengue-positive cases had thrombocytopenia, leucopenia, erythrocytosis, high hemoconcentration, low mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). However, binary logistic regression predicted platelet count, total leucocyte count, MCH, MCHC, neutrophil count and lymphocyte count as significant predictors of dengue positivity.: This study revealed the characteristics and demographics of dengue-positive cases and their associations with hematological parameters. Furthermore, the identified predictive markers can help healthcare professionals diagnose and manage dengue cases more promptly, potentially reducing the disease's burden.
{"title":"Insights of hematological parameters in dengue virus-infected patients","authors":"T. Thapa, B. R. Bhattarai, S. Maharjan, Sushant Pokhrel, M. Sapkota","doi":"10.18231/j.ijpo.2023.077","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.077","url":null,"abstract":": Early and accurate diagnosis of dengue is critical for prompt treatment and avoiding severe complications. Thus, the present study aimed to evaluate the serological and hematological parameters for predicting the dengue virus infection. : A laboratory-based cross-sectional study was conducted among the patients who visited Sumeru Hospital, Lalitpur, Nepal, from July 2022 to June 2023. Blood samples were collected from suspected dengue cases and tested using the rapid diagnostic immunochromatography (ICT) method, and hematological parameters were also assessed. The Mann-Whitney U test compared continuous variables between dengue-infected and non-infected groups. A binary logistic regression analysis was done to evaluate the association of variables for dengue positivity.: When compared to dengue-negative cases, dengue-positive cases had thrombocytopenia, leucopenia, erythrocytosis, high hemoconcentration, low mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). However, binary logistic regression predicted platelet count, total leucocyte count, MCH, MCHC, neutrophil count and lymphocyte count as significant predictors of dengue positivity.: This study revealed the characteristics and demographics of dengue-positive cases and their associations with hematological parameters. Furthermore, the identified predictive markers can help healthcare professionals diagnose and manage dengue cases more promptly, potentially reducing the disease's burden.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.093
Deepti Gupta, N. Trivedi, Abhimanyu Kapoor, Shefali Agarwal, A. Tewari
Mucormycosis is rare but emerging fungal infection. In the past decade, it has emerged as an important lethal infection in diabetics and immunocompromised patients. Rhinosinusitis, pansinusitis, rhino-orbital and rhino cerebral forms constitute the classic manifestations of this fungus. Gastrointestinal mucormycosis is an uncommon disease with high mortality most often affecting patients with immunocompromised state. A very few cases of this disease have been described among patients with no risk factors and no known comorbidites. Our study attributes to one such case of invasive gastric mucormycosis diagnosed incidentally on histopathologic examination.
{"title":"Gastric mucormycosis in an immunocompetent host: A case report","authors":"Deepti Gupta, N. Trivedi, Abhimanyu Kapoor, Shefali Agarwal, A. Tewari","doi":"10.18231/j.ijpo.2023.093","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.093","url":null,"abstract":"Mucormycosis is rare but emerging fungal infection. In the past decade, it has emerged as an important lethal infection in diabetics and immunocompromised patients. Rhinosinusitis, pansinusitis, rhino-orbital and rhino cerebral forms constitute the classic manifestations of this fungus. Gastrointestinal mucormycosis is an uncommon disease with high mortality most often affecting patients with immunocompromised state. A very few cases of this disease have been described among patients with no risk factors and no known comorbidites. Our study attributes to one such case of invasive gastric mucormycosis diagnosed incidentally on histopathologic examination.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"16 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.085
Shashirekha Patil, Nagarekha Kulkarni, Shanthi Manickyam, Shridevi S Hulikeri
: Gastrointestinal tumors, mainly esophagogastric and colorectal carcinomas constitute one of the major causes of morbidity and mortality worldwide. The early detection and treatment of gastrointestinal tumors has been shown to improve patient's survival significantly. The current study is carried out to know the efficiency of scrape cytology in diagnosis of large intestinal tumors by comparing with histopathological diagnosisThirty surgically removed large intestinal tumor specimens were studied. Scrapings were taken from representative areas of each specimen, spread on slides, stained with H/E and reported. The specimens were fixed in 10% formalin, grossed and routine histopathological processing was carried out, followed by staining with H/E, examined and reported. The diagnosis obtained by scrape cytology and histopathology was correlated and analyzedTotal 30 specimens were received and majority of them were of rectal tumors(20%) and sigmund colon tumors(20%), followed by rectosigmoid region tumors (17%). Over all the scrape cytology diagnosis showed concordance for 28 cases with histopathology diagnosis having diagnostic accuracy of 93.3%.:Scrape cytology is simple, rapid and economically feasible technique and can be useful as an adjunct for frozen section in intraoperative consultation.
{"title":"Scrape cytology – Diagnostic tool in large intestinal tumors","authors":"Shashirekha Patil, Nagarekha Kulkarni, Shanthi Manickyam, Shridevi S Hulikeri","doi":"10.18231/j.ijpo.2023.085","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.085","url":null,"abstract":": Gastrointestinal tumors, mainly esophagogastric and colorectal carcinomas constitute one of the major causes of morbidity and mortality worldwide. The early detection and treatment of gastrointestinal tumors has been shown to improve patient's survival significantly. The current study is carried out to know the efficiency of scrape cytology in diagnosis of large intestinal tumors by comparing with histopathological diagnosisThirty surgically removed large intestinal tumor specimens were studied. Scrapings were taken from representative areas of each specimen, spread on slides, stained with H/E and reported. The specimens were fixed in 10% formalin, grossed and routine histopathological processing was carried out, followed by staining with H/E, examined and reported. The diagnosis obtained by scrape cytology and histopathology was correlated and analyzedTotal 30 specimens were received and majority of them were of rectal tumors(20%) and sigmund colon tumors(20%), followed by rectosigmoid region tumors (17%). Over all the scrape cytology diagnosis showed concordance for 28 cases with histopathology diagnosis having diagnostic accuracy of 93.3%.:Scrape cytology is simple, rapid and economically feasible technique and can be useful as an adjunct for frozen section in intraoperative consultation.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"70 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nodular hidradenomas is an uncommon benign adnexal tumor that arises as nodules from eccrine sweat glands. Although it can appear at various sites, its occurrence in eyelids is extremely rare. The diagnosis is usually confirmed on histopathology, and the lesion poses a diagnostic challenge for cytopathologist and is rarely diagnosed on fine aspiration needle cytology (FNAC), which prompted us to report. Here we report a rare case of Nodular Hidradenoma in a 50-year male, that was initially diagnosed on FNAC and later confirmed on histopathology and IHC. Thus, our study emphasizes that FNAC can be used as a first line diagnostic modality for nodular lesions of skin.
{"title":"Nodular hidradenoma of eyelid – A rare case with cyto-histo corelation","authors":"Shushruta Mohanty, Sujata Panda, Samskruti Patnaik, Sheetal Sabat","doi":"10.18231/j.ijpo.2023.098","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.098","url":null,"abstract":"Nodular hidradenomas is an uncommon benign adnexal tumor that arises as nodules from eccrine sweat glands. Although it can appear at various sites, its occurrence in eyelids is extremely rare. The diagnosis is usually confirmed on histopathology, and the lesion poses a diagnostic challenge for cytopathologist and is rarely diagnosed on fine aspiration needle cytology (FNAC), which prompted us to report. Here we report a rare case of Nodular Hidradenoma in a 50-year male, that was initially diagnosed on FNAC and later confirmed on histopathology and IHC. Thus, our study emphasizes that FNAC can be used as a first line diagnostic modality for nodular lesions of skin.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"15 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138970633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.18231/j.ijpo.2023.099
Krishna Ramavath, G. Singh L., Reshmi Sultana, Sumitra Sivakoti, Adarsha A M, Harikrishna B, Siddharth S Rao
Invasive papillary carcinomas of breast are rare tumors. They account for approximately 0.5% of all Invasive breast carcinomas. Invasive papillary carcinomas are commonly present in post-menopause women. These tumors lack the myoepithelial cell layer (MCL) within the papillae or at the periphery of the tumor. The diagnosis is difficult due to different clinical and radiological features. Immunohistochemistry (IHC) is really essential to confirming the diagnosis. We are here presenting one index case of a rare variety of invasive papillary carcinoma of the left breast. We present a case of invasive papillary carcinoma of the left breast in a 55-year-old female presented with a retroareolar lump without nipple discharge. Preoperative core biopsy showed fibroadenoma with a papillary configuration.But post-operative histopathological examination revealed it was an invasive papillary carcinoma. Invasive papillary carcinoma of breast even though a rare entity, making a diagnosis is very challenging. Thorough preoperative clinical and radiological examination should be done, so that timely management as well as proper treatment is possible.
{"title":"Invasive solid papillary carcinoma of breast mimicking as a benign condition: Rare case report","authors":"Krishna Ramavath, G. Singh L., Reshmi Sultana, Sumitra Sivakoti, Adarsha A M, Harikrishna B, Siddharth S Rao","doi":"10.18231/j.ijpo.2023.099","DOIUrl":"https://doi.org/10.18231/j.ijpo.2023.099","url":null,"abstract":"Invasive papillary carcinomas of breast are rare tumors. They account for approximately 0.5% of all Invasive breast carcinomas. Invasive papillary carcinomas are commonly present in post-menopause women. These tumors lack the myoepithelial cell layer (MCL) within the papillae or at the periphery of the tumor. The diagnosis is difficult due to different clinical and radiological features. Immunohistochemistry (IHC) is really essential to confirming the diagnosis. We are here presenting one index case of a rare variety of invasive papillary carcinoma of the left breast. We present a case of invasive papillary carcinoma of the left breast in a 55-year-old female presented with a retroareolar lump without nipple discharge. Preoperative core biopsy showed fibroadenoma with a papillary configuration.But post-operative histopathological examination revealed it was an invasive papillary carcinoma. Invasive papillary carcinoma of breast even though a rare entity, making a diagnosis is very challenging. Thorough preoperative clinical and radiological examination should be done, so that timely management as well as proper treatment is possible.","PeriodicalId":486471,"journal":{"name":"Indian Journal of Pathology and Oncology","volume":"96 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138998797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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