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How Can Radiomics Help the Clinical Management of Patients with Acute Ischemic Stroke? 放射组学如何帮助急性缺血性脑卒中患者的临床管理?
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810061
Jacobo Porto-Álvarez, Antonio Mosqueira Martínez, Javier Martínez Fernández, Marta Sanmartín López, M. Blanco Ulla, F. Vázquez Herrero, J. Pumar, M. Rodríguez-Yáñez, Anxo Manuel Minguillón Pereiro, Alberto Bolón Villaverde, Ramón Iglesias Rey, M. Souto-Bayarri
Acute ischemic stroke (AIS) is the loss of neurological function due to a sudden reduction in cerebral blood flow and is a leading cause of disability and death worldwide. The field of radiological imaging has experienced growth in recent years, which could be boosted by the advent of artificial intelligence. One of the latest innovations in artificial intelligence is radiomics, which is based on the fact that a large amount of quantitative data can be extracted from radiological images, from which patterns can be identified and associated with specific pathologies. Since its inception, radiomics has been particularly associated with the field of oncology and has shown promising results in a wide range of clinical situations. The performance of radiomics in non-tumour pathologies has been increasingly explored in recent years, and the results continue to be promising. The aim of this review is to explore the potential applications of radiomics in AIS patients and to theorize how radiomics may change the paradigm for these patients in the coming years.
急性缺血性中风(AIS)是由于脑血流量突然减少而导致的神经功能丧失,是全世界致残和死亡的主要原因。近年来,放射成像领域经历了增长,人工智能的出现可能会推动这一增长。放射组学是人工智能领域的最新创新之一,它基于可以从放射图像中提取大量定量数据的事实,从中可以识别模式并将其与特定病理相关联。自成立以来,放射组学一直与肿瘤学领域密切相关,并在广泛的临床情况下显示出有希望的结果。近年来,放射组学在非肿瘤病理中的应用得到了越来越多的探索,结果也很有希望。这篇综述的目的是探讨放射组学在AIS患者中的潜在应用,并推测放射组学在未来几年如何改变这些患者的治疗模式。
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引用次数: 0
Quantitative Analysis of Coal Quality by a Portable Laser Induced Breakdown Spectroscopy and Three Chemometrics Methods 便携式激光诱导击穿光谱法和三种化学计量学方法定量分析煤质
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810049
Youquan Dou, Qingsong Wang, Sensheng Wang, Xi Shu, Minghui Ni, Yan Li
Laser-induced breakdown spectroscopy (LIBS) technology has the characteristics of small sample demand, simple sample preparation, simultaneous measurement of multiple elements and safety, which has great potential application in the rapid detection of coal quality. In this paper, 59 kinds of coal commonly used in Chinese power plants were tested by a lab-designed field-portable laser-induced breakdown spectrometer. The data set division methods and the quantitative analysis algorithm of ash content, volatile matter and calorific value of coal samples were carried out. The accuracy and prediction accuracy of three kinds of dataset partitioning methods, random selection (RS), Kennard–Stone (KS) and sample partitioning based on joint X-Y distances (SPXY), coupled with three quantitative algorithms, partial least squares regression (PLS), support vector machine regression (SVR) and random forest (RF), were compared and analyzed in this paper. The results show that the model featuring SPXY combined with RF has the best prediction performance. The R2 of ash content by the RF and SPXY method is 0.9843, the RMSEP of ash content is 1.3303 and the mean relative error (MRE) is 7.47%. The R2 of volatile matter is 0.9801, RMSEP is 0.7843 and MRE is 2.19%. The R2 of calorific value is 0.9844, RMSEP is 0.7324 and MRE is 2.27%. This study demonstrates that the field-portable LIBS device combining appropriate chemometrics algorithms has a wide application prospect in the rapid analysis of coal quality.
激光诱导击穿光谱(LIBS)技术具有样品需求量小、制样简单、多元素同时测量、安全性高等特点,在煤质快速检测中具有很大的应用潜力。本文利用实验室设计的现场便携式激光诱导击穿光谱仪对我国电厂常用的59种煤进行了测试。给出了煤样灰分、挥发物和热值的数据集划分方法和定量分析算法。本文对比分析了随机选择(RS)、Kennard-Stone (KS)和基于X-Y联合距离的样本划分(SPXY)三种数据集划分方法,以及偏最小二乘回归(PLS)、支持向量机回归(SVR)和随机森林(RF)三种定量算法的准确率和预测精度。结果表明,SPXY与RF相结合的模型具有较好的预测效果。RF - SPXY法测定的灰分含量R2为0.9843,RMSEP为1.3303,平均相对误差(MRE)为7.47%。挥发物的R2为0.9801,RMSEP为0.7843,MRE为2.19%。热值R2为0.9844,RMSEP为0.7324,MRE为2.27%。本研究表明,结合合适的化学计量学算法的现场便携式LIBS装置在煤质快速分析中具有广阔的应用前景。
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引用次数: 0
Development of a 7-DOF Biodynamic Model for a Seated Human and a Hybrid Optimization Method for Estimating Human-Seat Interaction Parameters 坐着人的7自由度生物动力学模型的开发和估计人-座相互作用参数的混合优化方法
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810065
Abeeb Opeyemi Alabi, Byoung-Gyu Song, Jong-Jin Bae, Namcheol Kang
Existing biodynamic models adopt apparent mass and seat-to-head transmissibility to predict the response of seated humans to whole-body vibration, limiting their ability to capture the actual response of distinct body segments in different excitation conditions. This study systematically develops a 7-DOF seated human model, a vibration experiment, and a novel hybrid optimization to estimate unknown mechanical parameters and predict the response of different human body segments to vertical vibrations. Experimental results showed that the upper trunk and head were most susceptible to transmitted vibrations. Combining the 7-DOF model and HOM resulted in accelerated optimization, improved numerical stability, and significant minimization of the objective function value compared to conventional algorithms. Notably, the estimated parameters, particularly stiffness, remained consistent regardless of increasing excitation magnitude or change in the body segment data used. Additionally, the model captured the non-linearity in human biodynamics through stiffness softening. These findings are applicable in seating systems optimization for comfort and safety.
现有的生物动力学模型采用表观质量和座椅-头部传递性来预测坐着的人对全身振动的反应,限制了他们在不同激励条件下捕捉不同身体段实际反应的能力。本研究系统地开发了一个7自由度的坐姿人体模型、一个振动实验和一种新的混合优化方法,以估计未知的机械参数并预测不同人体段对垂直振动的响应。实验结果表明,上躯干和头部最容易受到传递振动的影响。与传统算法相比,将7自由度模型和HOM相结合可以加速优化,提高数值稳定性,并显著最小化目标函数值。值得注意的是,无论所用身体节段数据的激励幅度增加或变化如何,估计的参数,特别是刚度,都保持一致。此外,该模型通过刚度软化捕捉到了人类生物动力学中的非线性。这些发现适用于座椅系统的舒适性和安全性优化。
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引用次数: 0
Fatty Acid Profile, Atherogenic and Thrombogenic Indices, and Meat Quality as the Effect of Feed Additive in African Catfish Clarias gariepinus (Burchell, 1822) 饲料添加剂对非洲鲇鱼脂肪酸谱、动脉粥样硬化和血栓形成指标及肉品质的影响(Burchell, 1822)
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810058
M. Bušová, L. Kouřimská, Marek Doležal, V. Ilko, D. Revenco, M. Zare, Jan Matoušek, I. Ferrocino, I. Franciosa, Petr Smejkal, Matěj Přeslička, M. Prokešová
Humic substances (HS) are often used as feesd additives in livestock feeding. The long-term effects of different concentrations of HS additives in aquafeed on growth and production performance, antioxidant status, stress resistance, gut microbiome, overall health condition, final product yield, sensory properties of fresh and cooked meat, and composition of fatty acids of market size in African catfish (Clarias gariepinus) originating from aquaculture were compared in this study. C. gariepinus were exposed to dietary inclusions of HS (0, 1, and 3, and 6% w/w) in a long-term experiment (six months in total) until fish reached market size. The growth parameters, condition factor, and selected somatic indices did not differ (p > 0.05) between the tested groups (HS0–HS6). Biochemical parameters were not different between the tested HS groups by the end of experiment, and only glucose (GLC) levels significantly increased (p < 0.05) with increasing concentrations of HS fed as an additive. The levels of cortisol (COR) and GLC did not differ between the tested groups (p > 0.05) after the stress challenge, but the results of GLC levels before and after the stress challenge showed an increasing tendency with increasing levels of HS addition in the diet. The levels of COR were slightly lower in groups HS3 and HS6 than in HS1 and the control group. In the case of protein and fat contents, differences between groups (HS0–HS6) were statistically insignificant. Significant differences were found, however, in water and ash content. In some cases, statistically significant differences were found in fatty acid profiles and in nutritional indices assessing fatty acids between samples. Sensory characteristics of fresh fillets did not differ between the tested groups HS0–HS6. The total content of polyphenols increased depending on the addition of humates. The main gut microbiota of samples analyzed (HS0–HS3 group) comprised the following three genera: Ralstonia, Pseudomonas and Cetobacterium; other genera were present in all samples at a low relative abundance: Staphylococcus, Bradyrhizobium, Bacillus, and Anaerobacillus. The relative abundance of Pseudomonas decreased while the presence of Cetobacterium increased in samples fed with 3% of HS. The results of our study yielded a comprehensive set of experimental results about African catfish fed with HS as additives. Although a significant effect of HS on overall performance of C. gariepinus was not proven, a positive effect on antioxidant status was seen as well as a decrease in gut microorganisms that can be present as pathogenic contaminants in aquatic environments.
腐殖物质(HS)经常被用作牲畜饲养中的饲料添加剂。水产饲料中不同浓度HS添加剂对生长和生产性能、抗氧化状态、抗逆性、肠道微生物组、整体健康状况、最终产品产量、新鲜和熟肉的感官特性的长期影响,本研究比较了原产于水产养殖的非洲鲶鱼(Clarias gariepinus)市场规模的脂肪酸组成。在一项长期实验中(总共六个月),C.gariepinus暴露于HS的饮食内含物(0、1、3和6%w/w)中,直到鱼类达到市场规模。受试组(HS0-HS6)的生长参数、条件因子和选定的体细胞指数没有差异(p>0.05)。到实验结束时,测试的HS组之间的生化参数没有差异,只有葡萄糖(GLC)水平随着作为添加剂的HS浓度的增加而显著增加(p<0.05)。应激挑战后,受试组之间的皮质醇(COR)和GLC水平没有差异(p>0.05),但应激挑战前后的GLC水平结果显示,随着饮食中HS添加水平的增加,GLC水平呈增加趋势。HS3和HS6组的COR水平略低于HS1和对照组。在蛋白质和脂肪含量的情况下,各组之间的差异(HS0-HS6)在统计学上不显著。然而,在水分和灰分方面发现了显著差异。在某些情况下,在脂肪酸图谱和评估样本之间脂肪酸的营养指数方面发现了统计学上的显著差异。新鲜鱼片的感官特征在测试组HS0-HS6之间没有差异。多酚的总含量随着腐殖酸盐的加入而增加。所分析样本的主要肠道微生物群(HS0-HS3组)包括以下三个属:雷氏菌属、假单胞菌属和Cetobacterium;其他属以较低的相对丰度存在于所有样本中:葡萄球菌、慢生根瘤菌、芽孢杆菌和厌氧杆菌。在喂食3%HS的样品中,假单胞菌的相对丰度降低,而Cetobacterium的存在增加。我们的研究结果得出了一套关于以HS为添加剂喂养非洲鲶鱼的全面实验结果。尽管HS对C.gariepinus的整体性能的显著影响尚未得到证实,但它对抗氧化状态有积极影响,并减少了在水生环境中可能作为致病污染物存在的肠道微生物。
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引用次数: 0
Effectiveness of Bonding Steel Elements with Polyester-Coated Paint 钢构件与聚酯涂层涂料结合的有效性
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810059
A. Rudawská, Arkadiusz Gola, J. Pizoń, Paweł Capała, Łukasz Wójcik
The aim of the paper is to assess the impact of the effectiveness of bonding steel elements with paint coating. The adhesive joints were made using two types of the adhesives: two-component epoxy resin adhesive based on Bisphenol A and polyurethane. Three types of adhesive joints were made: (i) reference samples, (ii) samples with a paint polyester coating, and (iii) samples with a zinc primer and paint polyester coating. These coatings were applied using the electrokinetic method. A shear strength test of the adhesive joints (EN DIN 1465 standard), a coating adhesion test (ASTM D3359-B standard), and surface wettability tests (based on contact angle) were used. Through analyzing the test results, it can be seen that the strength of the adhesive joints of the reference samples made with epoxy adhesive is 46% lower than that of the specimens with primer and paint coating applied. However, in the case of the adhesive joints made with the polyurethane adhesive, the aforementioned difference in the strength value of the adhesive joints of the reference samples and paint-coated samples with an applied primer is 76%. Adherends with a paint coating and a previously applied primer obtained the lowest value of the contact angle (38.72°) and are characterized by good wettability.
本文的目的是评估用油漆涂层粘合钢元件的有效性的影响。采用双酚A双组分环氧树脂胶粘剂和聚氨酯胶粘剂两种胶粘剂制作了粘接接头。制作了三种类型的粘合接头:(i)参考样品,(ii)具有涂料聚酯涂层的样品,以及(iii)具有锌底漆和涂料聚酯涂层。这些涂层是使用电动方法涂覆的。使用粘合接头的剪切强度测试(EN DIN 1465标准)、涂层附着力测试(ASTM D3359-B标准)和表面润湿性测试(基于接触角)。通过对试验结果的分析可以看出,使用环氧胶粘剂制成的参考样品的粘接接头强度比使用底漆和油漆涂层的样品低46%。然而,在用聚氨酯粘合剂制成的粘合接头的情况下,参考样品和涂有底漆的涂料样品的粘合接头强度值的上述差异为76%。具有油漆涂层和先前涂覆的底漆的粘附物获得了最低的接触角值(38.72°),并且具有良好的润湿性。
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引用次数: 0
Oscillating Nonlinear Acoustic Waves in a Mooney–Rivlin Rod Mooney-Rivlin棒中振动的非线性声波
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810037
A. Karakozova, Sergey Kuznetsov
Harmonic wave excitation in a semi-infinite incompressible hyperelastic 1D rod with the Mooney–Rivlin equation of state reveals the formation and propagation of the shock wave fronts arising between faster and slower moving parts of the initially harmonic wave. The observed shock wave fronts result in the collapse of the slower moving parts being absorbed by the faster parts; hence, to the attenuation of the kinetic and the elastic strain energy with the corresponding heat generation. Both geometrically and physically nonlinear equations of motion are solved by the explicit Lax–Wendroff numerical tine-integration scheme combined with the finite element approach for spatial discretization.
基于Mooney-Rivlin状态方程的半无限不可压缩超弹性一维棒中的谐波激发揭示了在初始谐波的快、慢运动部分之间产生的激波锋面的形成和传播。观测到的激波锋面导致运动较慢的部分坍塌,被运动较快的部分吸收;因此,随着相应的热生成,动能和弹性应变能的衰减。采用显式Lax-Wendroff数值时间积分格式结合空间离散化有限元方法求解几何和物理非线性运动方程。
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引用次数: 0
Study of Cyclic Plasticity and Creep Ratchet Behavior of PTFE PTFE的循环塑性和蠕变棘轮行为研究
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810039
Hongyan Liu, Lei Zhang, Kun Lu, Bingjun Gao
Due to its superior corrosion resistance and low coefficient of friction, polytetrafluoroethylene (PTFE) is extensively used in the aerospace, machinery, chemical, and pharmaceutical industries. However, PTFE components encounter complex alternating stresses, resulting in ratchet and creep, which will affect the component’s reliability. It is therefore necessary to clarify the PTFE’s resistance to ratchet and creep. In this paper, uniaxial ratchet and tensile creep experiments were conducted at five temperatures on a PTFE dog-bone tensile specimen. At various temperatures and stress levels, the effects of average stress and stress amplitude on the cyclic plastic behavior of PTFE were investigated. It is demonstrated that the ratchet strains and strain rates at 23 °C are greater than those at 50 °C. The reason for this is that the PTFE material exhibits different crystal states at these two temperatures. At temperatures above 50 °C, the ratchet strain and ratchet strain rate increase with temperature. At temperatures above 100 °C, the ratchet strain and ratchet strain rate of PTFE materials increase more rapidly due to the glass transition. By analyzing the creep strain and ratchet strain of specimens subjected to varying levels of average and amplitude stress, it was discovered that the creep strain and ratchet strain caused by the average stress under the same stress increment were greater than those caused by the amplitude stress.
聚四氟乙烯(PTFE)具有优异的耐腐蚀性和低摩擦系数,广泛应用于航空航天、机械、化工和制药行业。然而,PTFE部件会遇到复杂的交变应力,导致棘轮和蠕变,这将影响部件的可靠性。因此,有必要阐明PTFE对棘轮和蠕变的抵抗力。本文在聚四氟乙烯狗骨拉伸试样上进行了五种温度下的单轴棘轮蠕变和拉伸蠕变实验。研究了在不同温度和应力水平下,平均应力和应力幅值对PTFE循环塑性行为的影响。研究表明,23°C时的棘轮应变和应变速率大于50°C时。其原因是PTFE材料在这两个温度下表现出不同的结晶状态。在50°C以上的温度下,棘轮应变和棘轮应变速率随着温度的升高而增加。在100°C以上的温度下,由于玻璃化转变,PTFE材料的棘轮应变和棘轮应变速率增加得更快。通过分析不同平均应力和振幅应力水平下试样的蠕变应变和棘轮应变,发现在相同应力增量下,平均应力引起的蠕变应变及棘轮应变大于振幅应力引起。
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引用次数: 0
Application of Traffic Weighted Multi-Maps Based on Disjoint Routing Areas for Static Traffic Assignment 基于非联合路由区域的交通加权多地图在静态交通分配中的应用
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810071
Alvaro Paricio-Garcia, Miguel A. López-Carmona
Urban traffic congestion is a pressing issue, demanding effective and cost-efficient solutions. This paper develops the Traffic Weighted Multi-Maps (TWM) method to solve the Traffic Assignment Problem in Intelligent Transportation Systems (ITS). TWM offers drivers diverse views of the network, promoting path diversity and adaptability. Providing an optimal TWM configuration to the traffic demand in terms of structure and allocation policy is a challenging issue as it usually depends on the size of the network and its complexity. The paper explores TWM generation and assignment by applying routing areas based on semi-disjointed k-shortest paths and allocating them using a per-sub flow optimized assignment policy. This approach allows obtaining a pseudo-optimal solution for static traffic assignment with similar results in terms of total travel time compared to the direct solution of calculating optimal map weights and the theoretical system optimum. It offers a cost-effective solution valid for wide urban areas, as the TWM calculation depends on the variety of the traffic flows and the number of semi-disjoint routing areas considered instead of the network complexity and size. Urban network experiments with synthetic traffic demands are studied under different TWM adoption rates, comparing results with existing traffic assignment policies and estimation methods. It highlights its potential for enhancing urban traffic management. Overall, TWM presents a promising approach to addressing urban traffic congestion efficiently.
城市交通拥堵是一个紧迫的问题,需要有效和经济的解决方案。针对智能交通系统中的交通分配问题,提出了交通加权多地图(TWM)方法。TWM为驾驶员提供了不同的网络视图,促进了路径的多样性和适应性。在结构和分配策略方面为流量需求提供最优的TWM配置是一个具有挑战性的问题,因为它通常取决于网络的规模和复杂性。本文通过应用基于半不相交k-最短路径的路由区域,并使用每子流优化分配策略对TWM的生成和分配进行了探讨。这种方法可以获得静态交通分配的伪最优解,与计算最优地图权重和理论系统最优的直接解相比,在总行程时间方面具有相似的结果。它提供了一个经济有效的解决方案,适用于广泛的城市地区,因为TWM的计算取决于交通流的变化和考虑的半不连接路由区域的数量,而不是网络的复杂性和规模。研究了不同TWM采用率下具有综合交通需求的城市网络实验,并与现有的交通分配策略和估计方法进行了比较。它突出了它在加强城市交通管理方面的潜力。总体而言,TWM提供了一种有效解决城市交通拥堵的有前途的方法。
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引用次数: 1
Synergistic Effect of Nonthermal Plasma and ZnO Nanoparticles on Organic Dye Degradation 非热等离子体和ZnO纳米颗粒对有机染料降解的协同效应
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810045
E. Abdel-Fattah, S. Alotibi
The synergetic effect of nonthermal plasma and ZnO nanoparticles (NPs) on the degradation efficiency of methylene blue was investigated. First, the ZnO nanoparticles were synthesized via the hydrothermal route; the spherical nanoparticles had diameters of 30–50 nm, as observed with a scanning electron microscope (SEM), and had hexagonal ZnO lattice structures, which was confirmed by both X-ray diffraction (XRD) and Raman spectroscopy. The X-ray-photoemission spectroscopy confirmed the ZnO composition and the presence of oxygen vacancies; meanwhile, the optical band gap energy was 3.17 eV. The optical emission of plasma radiation confirmed the presence of various active plasma species. Second, it was found that the maximum degradation efficiency of MB after 60 min was 85% in plasma alone and increased to 95% when combined with 0.2 gL−1 ZnO; but this decreased to 75% when ZnO loading increased to 0.4 gL−1. These results clearly show that combining plasma with the right amount of ZnO is a promising advanced oxidation technique as it provides an additional source of hydroxyl radicals and, at the same time, a source of photons that can excite the ZnO catalyst. The degradation mechanism for plasma alone and the plasma in combination with ZnO was presented.
研究了非热等离子体和ZnO纳米粒子对亚甲基蓝降解效率的协同效应。首先,采用水热法制备ZnO纳米颗粒;扫描电镜(SEM)观察到纳米颗粒直径为30 ~ 50 nm, x射线衍射(XRD)和拉曼光谱(Raman spectroscopy)证实了纳米颗粒具有六边形ZnO晶格结构。x射线光发射光谱证实了ZnO的组成和氧空位的存在;光学带隙能量为3.17 eV。等离子体辐射的光学发射证实了各种活性等离子体的存在。其次,发现单独在等离子体中,MB在60 min后的最大降解效率为85%,当与0.2 gL−1 ZnO结合时,降解效率提高到95%;但当ZnO负载增加到0.4 gL−1时,这一比例下降到75%。这些结果清楚地表明,将等离子体与适量的ZnO结合是一种很有前途的高级氧化技术,因为它提供了额外的羟基自由基来源,同时也提供了可以激发ZnO催化剂的光子来源。介绍了等离子体单独降解和等离子体与氧化锌复合降解氧化锌的机理。
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引用次数: 0
Editorial on “Design, Analysis, and Measurement of Antennas” 《天线的设计、分析与测量》社论
IF 2.7 4区 综合性期刊 Q2 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2023-09-06 DOI: 10.3390/app131810069
Nasser Ojaroudi
The area of modern wireless communication systems has experienced rapid growth, leading to a rising demand for multifunctional devices capable of providing various wireless services [...]
现代无线通信系统领域经历了快速增长,导致对能够提供各种无线服务的多功能设备的需求不断上升[…]
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引用次数: 1
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