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Music in Pregnancy to Improve Maternal Stress Resilience in Favor of the Offspring: A Systematic Review 怀孕期间的音乐可以提高母亲对后代的压力恢复力:一项系统综述
Pub Date : 2023-11-14 DOI: 10.22541/au.169994769.97119684/v1
Johanna Maul, Susann Behnam, Pauline Wimberger, Birgit Arabin
Abstract Background : Maternal mental health influences the metabolism and growth of fetal brain structures affecting their skills up to adulthood. Objective: Main objective is whether music interventions improve modifiable maternal health outcomes. Search Strategy: Up to July 2023, randomized controlled trials (RCTs) investigating music during pregnancy were identified using MEDLINE, CENTRAL, WEB OF SCIENCE. Selection Criteria: Using COVIDENCE reviewers screened for RCTs with >3 interventions applying the Perceived Stress Scale (PSS), State-Trait-Anxiety Inventory (STAI), Edinburgh Postnatal Depression Scale (EPDS), or blood pressure (BP) as outcome measures. Data Collection and Analysis: The revised Cochrane risk-of-bias tool (RoB2) and the reversed Cohen’s d were applied to investigate the impact of target groups, frequency, type and selection of music programs. The review was registered via PROSPERO CRD42022299950. Main Results: From 251 records, 14 RCTs (16 intervention arms) and 2375 pregnancies were included. Music interventions varied from 3 to 84 active or passive music sessions per pregnancy or 10 to 60 minutes per day and significantly decreased PSS in 2/4, STAI in 8/9, EPDS in 3/4 and BP in 3/4 RCTs. RoB2 was high in 5/14, or “with concerns” in 9/14 studies. Stratifying the Cohen’s d in 14 interventions arms suggested a big effect in 234/469 mothers on BP, and in 244/489 mothers on maternal anxiety. Conclusion: The findings show the dretailed potential of music interventions on maternal BP, stress resilience or anxiety complementing our research on complex music interventions throughout pregnancy in times of pandemics, violent conflicts, or natural catastrophes. Funding: Clara Angela Foundation. Key words: Music in pregnancy, systematic review, maternal stress, anxiety, and depression.
背景:母亲的心理健康影响胎儿大脑结构的代谢和生长,影响其成年后的技能。目的:主要目的是音乐干预是否能改善可修改的孕产妇健康结果。搜索策略:截至2023年7月,通过MEDLINE, CENTRAL, WEB OF SCIENCE确定了调查怀孕期间音乐的随机对照试验(rct)。选择标准:使用covid - ence审查人员筛选具有3种干预措施的随机对照试验,采用感知压力量表(PSS)、状态-特质-焦虑量表(STAI)、爱丁堡产后抑郁量表(EPDS)或血压(BP)作为结果测量。数据收集与分析:应用修正后的Cochrane风险偏倚工具(RoB2)和反向的Cohen’s d来调查目标群体、频率、音乐节目类型和选择的影响。该审查通过PROSPERO注册,编号为CRD42022299950。主要结果:251例记录,14项随机对照试验(16个干预组),2375例妊娠。音乐干预从每次怀孕3到84次主动或被动音乐或每天10到60分钟不等,显著降低了2/4的PSS, 8/9的STAI, 3/4的EPDS和3/4的BP。在5/14的研究中,RoB2是高的,或者在9/14的研究中是“值得关注的”。对14个干预组的科恩d进行分层表明,234/469组母亲对血压有很大影响,244/489组母亲对母亲焦虑有很大影响。结论:研究结果显示了音乐干预对孕妇血压、压力恢复力或焦虑的详细潜力,补充了我们对流行病、暴力冲突或自然灾害期间怀孕期间复杂音乐干预的研究。资助:Clara Angela基金会。关键词:孕期音乐,系统评价,母亲压力,焦虑,抑郁。
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引用次数: 0
Roles of ROS and redox in regulating cell-to-cell communication: Spotlight on viral modulation of redox for local spread 活性氧和氧化还原在调节细胞间通讯中的作用:聚焦于局部传播中氧化还原的病毒调节
Pub Date : 2023-11-14 DOI: 10.22541/au.169998557.72873233/v1
Tessa M. Burch-Smith, Mazen Alazem
Reactive oxygen species are important signaling molecules that influence many aspects of plant biology. One way in which ROS influence plant growth and development is by modifying intercellular trafficking through plasmodesmata (PD). Viruses have evolved to use plasmodesmata for their local cell-to-cell spread between plant cells, so it is therefore not surprising that they have found ways to modulate ROS and redox signaling to optimize plasmodesmata function for their benefit. This review examines how intracellular signaling via ROS and redox pathways regulate intercellular trafficking via PD during development and stress. The relationship between viruses and ROS-redox systems, and the strategies viruses employ to control PD function by interfering with ROS-redox in plants is also discussed.
活性氧是影响植物生物学许多方面的重要信号分子。活性氧影响植物生长发育的一种方式是通过胞间连丝(plasmodesmata, PD)调节细胞间运输。病毒已经进化到利用胞间连丝在植物细胞间进行局部细胞间传播,因此它们找到了调节ROS和氧化还原信号的方法来优化胞间连丝的功能,这并不奇怪。本文综述了细胞内信号通过ROS和氧化还原途径调节PD在发育和应激过程中的细胞间运输。本文还讨论了病毒与ros -氧化还原系统的关系,以及病毒通过干扰植物ros -氧化还原来控制PD功能的策略。
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引用次数: 0
Artemisia annua sublingual immunotherapy in children with seasonal allergic rhinitis 青蒿舌下免疫治疗儿童季节性变应性鼻炎
Pub Date : 2023-11-14 DOI: 10.22541/au.169993895.57319377/v1
Wntong Ge, Lixing Tang, Pengpeng Wang, Xiaojian Yang, Jinchi Zhao, Chong Pang, Li Xiang
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引用次数: 0
PoroFluidics: Deterministic fluid control in porous microfluidics 多孔流体:多孔微流体的确定性流体控制
Pub Date : 2023-11-14 DOI: 10.22541/essoar.170000020.03410573/v1
Zhongzheng Wang, Louis Jun Ye Ong, Yixiang Gan, Jean-Michel Pereira, Jun Zhang, Yi-Chin Toh, Emilie Sauret
Microfluidic devices with open lattice structures, equivalent to a type of porous media, allow for the manipulation of fluid transport processes while having distinct structural, mechanical, and thermal properties. However, a fundamental understanding of the design principles for the solid structure in order to achieve consistent and desired flow patterns remains a challenge, preventing its further development and wider applications. Here, through quantitative and mechanistic analyses of the behavior of multi-phase phenomena that involve gas-liquid-solid interfaces, we present a design framework for a new class of microfluidic devices containing porous architectures (referred to as poroFluidics) for deterministic control of multi-phase fluid transport processes. We show that the essential properties of the fluids and solid, including viscosity, interfacial tension, wettability, as well as solid manufacture resolution, can be incorporated into the design to achieve consistent flow in porous media, where the desired spatial and temporal fluid invasion sequence can be realized. Experiments and numerical simulations reveal that different preferential flow pathways can be controlled by solid geometry, flow conditions, or fluid/solid properties. Our design framework enables precise, multifunctional, and dynamic control of multi-phase transport within engineered porous media, unlocking new avenues for developing cost-effective, programmable microfluidic devices for manipulating multi-phase flows.
具有开放晶格结构的微流体装置,相当于一种多孔介质,允许操纵流体传输过程,同时具有独特的结构,机械和热性能。然而,为了实现一致和理想的流动模式,对固体结构设计原则的基本理解仍然是一个挑战,阻碍了它的进一步发展和更广泛的应用。在这里,通过对涉及气液固界面的多相现象行为的定量和机制分析,我们提出了一种新型微流体装置的设计框架,该装置包含多孔结构(称为多孔流体),用于多相流体输送过程的确定性控制。我们表明,流体和固体的基本特性,包括粘度、界面张力、润湿性以及固体制造分辨率,可以纳入设计中,以实现多孔介质中的一致流动,从而实现所需的空间和时间流体侵入顺序。实验和数值模拟表明,不同的优先流动路径可以由固体几何形状、流动条件或流体/固体性质控制。我们的设计框架能够精确、多功能和动态地控制工程多孔介质中的多相传输,为开发具有成本效益的、可编程的微流体设备来操纵多相流开辟了新的途径。
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引用次数: 0
An unusual presentation of severe obstructive sleep apnoea with nocturnal seizure-like movements: a case report 严重阻塞性睡眠呼吸暂停伴夜间癫痫样运动的不寻常表现:1例报告
Pub Date : 2023-11-14 DOI: 10.22541/au.169994772.29945637/v1
negin rahimi, Hamed Amirifard, Melika Jameie
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引用次数: 0
Rainfall interception of urban trees: event characteristics and tree morphological traits 城市树木截流:事件特征和树木形态特征
Pub Date : 2023-11-14 DOI: 10.22541/au.169999569.96302150/v1
Markus Anys, Markus Weiler
The rapid expansion of impermeable surfaces in cities has a major impact on urban hydrology. Infiltration of rainwater is reduced and water runs off faster with higher runoff peaks. Urban trees as stormwater management tools are becoming more relevant to reduce flood risks in addition to other ecosystem services. An in-situ field experiment to measure throughfall on Norway maple ( Acer platanoides ) and small-leaved lime ( Tilia cordata ) was conducted to determine the interception of solitary urban trees with different degrees of surface sealing in the city of Freiburg, Germany. The relationships between rainfall characteristics, tree morphological traits, and the interception behavior were investigated with eight trees per species. 76 recorded rainfall events were evaluated from April to September 2021. Average interception values were higher for small-leaved lime (70.3 ± 6.6%) than for Norway maple (54.8 ± 10.3%) and hence much higher than in a typical forested environment. The average interception loss of all recorded events was 2.58 ± 0.60 mm for Norway maple and 3.73 ± 0.29 mm for small-leaved lime. For both tree species, significant linear correlations were found between the relative interception and other factors like rainfall depths, the leaf area index (LAI), and the plant area index (PAI) (adj.R > 0.45). In contrast to Norway maple, small-leaved lime also showed significant relationships of several tree morphological parameters with the interception (adj.R > 0.43). LAI, which also effects the interception, of both tree species significantly decreased with the degree of surface sealing. Our results provide a better understanding of the interception process of solitary trees for different urban sites and allows to parameterize interception based on measurable properties. However, further field experiments with various tree species need to be conducted to obtain a larger database for typical parameters in models and to support urban planners in managing stormwater runoff.
城市不透水地表的迅速扩大对城市水文产生了重大影响。雨水的入渗减少,水流得更快,径流峰值也更高。除了其他生态系统服务外,城市树木作为雨水管理工具在减少洪水风险方面正变得越来越重要。在德国弗莱堡(Freiburg)进行了挪威枫(Acer platanoides)和小叶石灰(Tilia cordata)的通流测量现场试验,以确定不同程度地表密封的城市树木的拦截能力。研究了降雨特征、树木形态特征和截留行为之间的关系。对2021年4月至9月期间的76次记录降雨事件进行了评估。小叶石灰的平均截留值(70.3±6.6%)高于挪威枫(54.8±10.3%),远高于典型森林环境。挪威枫的平均截留损失为2.58±0.60 mm,小叶石灰的平均截留损失为3.73±0.29 mm。两种树种的相对截留量均与降雨深度、叶面积指数(LAI)、植物面积指数(PAI)等因子呈显著的线性相关(adj.R >0.45)。与挪威枫相比,小叶酸橙的几个形态参数与截留量也有显著的关系(adj.R >0.43)。两树种的叶面积指数随地表封密程度显著降低,叶面积指数也影响截留。我们的研究结果可以更好地理解不同城市站点的孤立树拦截过程,并允许基于可测量属性的参数化拦截。但是,需要对不同树种进行进一步的实地试验,以获得模型中典型参数的更大数据库,并支持城市规划者管理雨水径流。
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引用次数: 0
Failure characteristics and stress wave propagation of red sandstone under explosion with varying gas energies 变瓦斯能爆炸作用下红砂岩破坏特征及应力波传播
Pub Date : 2023-11-14 DOI: 10.22541/au.169995674.42778071/v1
Xiang Zhang, Jun Chen, Hui Yi, Yang Yang, Shizheng Fang, Chengxiao Li, Shulin Chen, Derui Gao, Zhijie Wang
The blasting excavation process during underground rock mass engineering can induce severe stress disturbance, resulting in spalling and damage to the surrounding rock mass in the tunnels, which can seriously compromise the underground engineering construction. In the present work, an experimental blast loading device was developed to study the dynamic response of rocks under explosive loads, which could vary the utilization of explosive gas energy by changing the constraint conditions. The device employed a high-speed camera to record the stress wave propagation and failure characteristics on the surface of the specimen and verified the reliability of the experimental results using an ultra-dynamic strain gauge. The developed apparatus was used to explore the failure characteristics and stress wave propagation laws in red sandstone under different explosion gas energies. The complete process of stress wave propagation in red sandstone was captured under different explosive gas energies, from an intact form to failure, and the attenuation law of stress waves was obtained. The experimental results showed that when the explosive stress wave traversed through the specimen, it primarily experienced tensile strain, with maximum tensile strain observed at the free surface. The stress wave propagation in the specimen varied under different explosive loads, leading to varying overall failure characteristics of the specimen. The larger the amplitude of the stress wave, the greater the spatial attenuation coefficients of the compression wave and the tensile wave. The thickness of the spalling fracture was determined based on the wave width of the stress wave λ , the attenuation coefficient of the stress wave α , and the longitudinal wave velocity C . The closer the crack is to the bottom of the specimen, the smaller the thickness. The experimental results provide theoretical guidance to understand the strong dynamic disturbance behavior and progressive instability failure phenomenon in deep underground engineering.
地下岩体工程爆破开挖过程中会产生严重的应力扰动,导致隧道围岩剥落和破坏,严重影响地下工程建设。为了研究岩石在爆炸载荷作用下的动态响应,本文研制了一种爆炸加载实验装置,通过改变约束条件来改变爆炸气体能量的利用率。该装置采用高速摄像机记录试样表面应力波传播和破坏特征,并利用超动态应变仪验证实验结果的可靠性。利用研制的试验装置,研究了不同爆炸气体能量作用下红砂岩的破坏特征和应力波传播规律。捕捉了不同爆炸气体能量作用下应力波在红砂岩中从完整形态到破坏的完整过程,得到了应力波的衰减规律。实验结果表明:爆炸应力波通过试样时,试样主要经历拉伸应变,在自由表面观察到最大的拉伸应变;在不同的爆炸荷载作用下,应力波在试样中的传播是不同的,从而导致试样的整体破坏特征不同。应力波幅值越大,压缩波和拉伸波的空间衰减系数越大。根据应力波波长λ、应力波衰减系数α和纵波速度C确定裂缝厚度。裂纹越靠近试件底部,厚度越小。试验结果为理解深埋地下工程的强动力扰动行为和进行性失稳破坏现象提供了理论指导。
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引用次数: 0
Anthropogenic Heat, a More Credible Threat to the Earth's Climate than Carbon Dioxide 人为热,对地球气候的威胁比二氧化碳更可信
Pub Date : 2023-11-14 DOI: 10.22541/essoar.170000336.69527212/v1
Michel Vert
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引用次数: 0
SupplementaryMaterial_MarsAlluvialFan_Thermal_Inertia_summary SupplementaryMaterial_MarsAlluvialFan_Thermal_Inertia_summary
Pub Date : 2023-11-14 DOI: 10.22541/essoar.167768127.72084291/v2
Claire A. Mondro
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引用次数: 0
Capturing the diversity of mesoscale trade wind cumuli using complementary approaches from self-supervised deep learning 利用自监督深度学习的互补方法捕捉中尺度信风积云的多样性
Pub Date : 2023-11-14 DOI: 10.22541/essoar.170000384.49382400/v1
Dwaipayan Chatterjee, Sabrina Schnitt, Paula Bigalke, Claudia Acquistapace, Susanne Crewell
At the mesoscale, trade wind clouds organize with a wide variety of spatial arrangements, which influences their effect on Earth’s energy budget. Past studies used high-resolution satellite measurements and clustering/labeling techniques to classify trade wind clouds into distinct classes. However, these methods only capture a part of the observed organization variability. This work proposes an integrated framework using a continuous followed by discrete self-supervised deep learning approach based on cloud optical depth from geostationary satellite measurements. The neural network learns the semantics of cloud system structure and distribution, verified through visualizations of different layers. Our analysis compares classes defined by human labels with machine-identified classes, aiming to address the uncertainties and limitations of both approaches. Additionally, we illustrate a case study of sugar-to-flower transitions, a novel aspect not covered by existing methods.
在中尺度,信风云以各种各样的空间排列组织,这影响了它们对地球能量收支的影响。过去的研究使用高分辨率卫星测量和聚类/标记技术将信风云划分为不同的类别。然而,这些方法只捕获了观察到的组织可变性的一部分。这项工作提出了一个集成框架,使用基于地球同步卫星测量的云光学深度的连续跟随离散自监督深度学习方法。神经网络学习云系统结构和分布的语义,并通过不同层的可视化进行验证。我们的分析比较了人类标签定义的类和机器识别的类,旨在解决这两种方法的不确定性和局限性。此外,我们还举例说明了糖到花转换的案例研究,这是现有方法未涵盖的一个新方面。
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引用次数: 0
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