Pub Date : 2025-07-28DOI: 10.1016/j.jvc.2025.07.006
M.Y.-W. Kuo , M. Dirven , J. Häggström , S.G. Gordon , K. Höglund , E. Côté , T.-L. Lu , M. Rishniw , Y.-W. Hung , I. Ljungvall
Introduction/Objectives
This study aimed to investigate veterinary echocardiographers’ preferences for assessing left atrial (LA) size in dogs using linear two-dimensional echocardiography, focusing on image selection, timing, caliper placement, and thresholds used for LA enlargement. A secondary aim was to explore the impact of experience and training on echocardiographers' linear two-dimensional measurements of LA size in dogs.
Animals, Materials and Methods
A global online study was conducted, asking veterinary echocardiographers to measure LA size using static echocardiographic images.
Results
A total of 533 echocardiographers (63% non-specialists and 37% specialists, of which 43% were cardiology board certified) completed the study. Most echocardiographers (86%, n = 459/533) used a right parasternal short-axis (RPSAX) view for LA and aortic (Ao) measurements. Of these, 57% (n = 261/459) favored the same image angulation for performing measurements and 76% (n = 351/459) timed measurements at end-systole/early-diastole. Caliper placement near pulmonary venous inlets impacted their LA dimension measurements the most. Thirty-nine percent (n = 207/533) used right parasternal long-axis (RPLAX) views. The upper limit for LA enlargement varied across all commonly used methods. Training and experience level influenced interobserver variation for LA dimension measurements obtained from a RPLAX four-chamber view, but not from a RPSAX view.
Study Limitations
Static images may not reflect real-time clinical settings or allow precise identification of anatomical structures.
Conclusions
The RPSAX view was most favored for LA size assessment in dogs, but variations existed in image selection, timing, caliper placement, and threshold used for LA enlargement. Training and experience level influenced interobserver variation in LA dimension measurements obtained from a RPLAX four-chamber view.
{"title":"Veterinary echocardiographers’ preferences for image selection, timing, and caliper placement for left atrial two-dimensional size assessment in dogs: the BENEFIT project","authors":"M.Y.-W. Kuo , M. Dirven , J. Häggström , S.G. Gordon , K. Höglund , E. Côté , T.-L. Lu , M. Rishniw , Y.-W. Hung , I. Ljungvall","doi":"10.1016/j.jvc.2025.07.006","DOIUrl":"10.1016/j.jvc.2025.07.006","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>This study aimed to investigate veterinary echocardiographers’ preferences for assessing left atrial (LA) size in dogs using linear two-dimensional echocardiography, focusing on image selection, timing, caliper placement, and thresholds used for LA enlargement. A secondary aim was to explore the impact of experience and training on echocardiographers' linear two-dimensional measurements of LA size in dogs.</div></div><div><h3>Animals, Materials and Methods</h3><div>A global online study was conducted, asking veterinary echocardiographers to measure LA size using static echocardiographic images.</div></div><div><h3>Results</h3><div>A total of 533 echocardiographers (63% non-specialists and 37% specialists, of which 43% were cardiology board certified) completed the study. Most echocardiographers (86%, n = 459/533) used a right parasternal short-axis (RPSAX) view for LA and aortic (Ao) measurements. Of these, 57% (n = 261/459) favored the same image angulation for performing measurements and 76% (n = 351/459) timed measurements at end-systole/early-diastole. Caliper placement near pulmonary venous inlets impacted their LA dimension measurements the most. Thirty-nine percent (n = 207/533) used right parasternal long-axis (RPLAX) views. The upper limit for LA enlargement varied across all commonly used methods. Training and experience level influenced interobserver variation for LA dimension measurements obtained from a RPLAX four-chamber view, but not from a RPSAX view.</div></div><div><h3>Study Limitations</h3><div>Static images may not reflect real-time clinical settings or allow precise identification of anatomical structures.</div></div><div><h3>Conclusions</h3><div>The RPSAX view was most favored for LA size assessment in dogs, but variations existed in image selection, timing, caliper placement, and threshold used for LA enlargement. Training and experience level influenced interobserver variation in LA dimension measurements obtained from a RPLAX four-chamber view.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"62 ","pages":"Pages 1-16"},"PeriodicalIF":1.3,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144858132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-26DOI: 10.1016/j.jvc.2025.07.005
K.M. Buchanan, R.C. Fries, S. Kadotani
Introduction/Objectives
Cats with left-sided congestive heart failure (CHF) usually present with pleural effusion and/or pulmonary edema. We compared time to refractory CHF and survival time between pleural effusion and pulmonary edema in cats with various cardiomyopathies.
Animals, Material and Methods
A total of 125 cats with CHF presenting as predominantly pleural effusion (n = 73) or pulmonary edema (n = 52) were included in this study. Medical records of cats presenting with CHF between 2013 and 2022 were evaluated retrospectively. Refractory CHF was defined as one requiring greater than 6 mg/kg/day of furosemide or introduction of torsemide. Signalment, underlying cardiomyopathy, the presence of pleural effusion or pulmonary edema, echocardiographic measurements at the time of CHF diagnosis, medications, comorbidities, time to refractory CHF, and survival time were recorded.
Results
The median survival time was significantly shorter (P=0.0002) for cats with pleural effusion (155 days; 95% confidence interval [CI]: 11–199 days) than for those with pulmonary edema (234 days; 95% CI: 177–509 days). Median time to refractory CHF was significantly shorter (P=0.0003) for cats with pleural effusion (44 days; 95 % CI: 32–67 days) than for those with pulmonary edema (133 days; 95% CI: 90–233 days). Pleural effusion significantly influenced time to refractory CHF (hazard ratio [HR]: 2.26; 95% CI: 1.16–4.62; P=0.022) and median survival time (HR: 1.87; 95% CI: 1.06–3.40; P=0.029) in the multivariable models.
Study Limitations
The limitations of this study were therapeutic recommendations not standardized and quantification of pleural effusion and fluid analysis not available for all cats.
Conclusions
In this study sample, cats with pleural effusion have a reduced time to refractory CHF and survival times compared to cats with pulmonary edema.
{"title":"Time to refractory congestive heart failure in cats presenting with pleural effusion vs. pulmonary edema","authors":"K.M. Buchanan, R.C. Fries, S. Kadotani","doi":"10.1016/j.jvc.2025.07.005","DOIUrl":"10.1016/j.jvc.2025.07.005","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Cats with left-sided congestive heart failure (CHF) usually present with pleural effusion and/or pulmonary edema. We compared time to refractory CHF and survival time between pleural effusion and pulmonary edema in cats with various cardiomyopathies.</div></div><div><h3>Animals, Material and Methods</h3><div>A total of 125 cats with CHF presenting as predominantly pleural effusion (n = 73) or pulmonary edema (n = 52) were included in this study. Medical records of cats presenting with CHF between 2013 and 2022 were evaluated retrospectively. Refractory CHF was defined as one requiring greater than 6 mg/kg/day of furosemide or introduction of torsemide. Signalment, underlying cardiomyopathy, the presence of pleural effusion or pulmonary edema, echocardiographic measurements at the time of CHF diagnosis, medications, comorbidities, time to refractory CHF, and survival time were recorded.</div></div><div><h3>Results</h3><div>The median survival time was significantly shorter (P=0.0002) for cats with pleural effusion (155 days; 95% confidence interval [CI]: 11–199 days) than for those with pulmonary edema (234 days; 95% CI: 177–509 days). Median time to refractory CHF was significantly shorter (P=0.0003) for cats with pleural effusion (44 days; 95 % CI: 32–67 days) than for those with pulmonary edema (133 days; 95% CI: 90–233 days). Pleural effusion significantly influenced time to refractory CHF (hazard ratio [HR]: 2.26; 95% CI: 1.16–4.62; P=0.022) and median survival time (HR: 1.87; 95% CI: 1.06–3.40; P=0.029) in the multivariable models.</div></div><div><h3>Study Limitations</h3><div>The limitations of this study were therapeutic recommendations not standardized and quantification of pleural effusion and fluid analysis not available for all cats.</div></div><div><h3>Conclusions</h3><div>In this study sample, cats with pleural effusion have a reduced time to refractory CHF and survival times compared to cats with pulmonary edema.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"62 ","pages":"Pages 52-59"},"PeriodicalIF":1.3,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-26DOI: 10.1016/j.jvc.2025.07.002
K. Kurogochi , Y. Nii , A. Chen , M. Uechi
Introduction/Objectives
Reperfusion ventricular fibrillation (VF) commonly occurs during open-heart surgery in dogs and humans. Pharmacological defibrillation using cardioplegia is a potential option; however, the standard technique remains unclear in dogs. We examined the clinical utility of pharmacological defibrillation in canine mitral valve repair.
Animals, Materials, and Methods
We retrospectively investigated 402 client-owned dogs that underwent mitral valve repair between January and December 2021.
Results
Ventricular fibrillation after cross-clamp release occurred in 70 of 397 cases (17.6%). Pharmacological defibrillation was attempted in 69 patients by administering 40 mEq/L potassium crystalloid cardioplegia via an aortic root catheter. If defibrillation was not achieved or VF recurred, the administration was repeated identically. In all cases, VF resolved after pharmacological defibrillation alone, without electrical defibrillation. Defibrillation was achieved with a single dose in 45 cases (median, 3.90 mL/kg; interquartile range [IQR], 2.95–4.95]), while multiple doses (range: 2–5) were necessary for 24 cases (median initial dose, 3.05 mL/kg [IQR, 2.07–4.14]). Predictors of reperfusion VF included body temperature at cross-clamp release (risk ratio, 0.82 per 1.0 °C) and pre-operative left ventricular internal dimension at end-diastole normalized to body weight (risk ratio, 1.11 per 0.1 unit).
Study Limitations
The retrospective nature of the study led to variability in personnel, absence of a control group, and limited data availability.
Conclusions
Reperfusion VF occurred in 17.6% of the canine mitral valve repair cases. Pharmacological defibrillation is a feasible option in such cases. Approximately 4.0 mL/kg of cardioplegia was effective for a single dose, whereas lower doses required multiple administrations.
{"title":"Clinical utility of pharmacological defibrillation using cardioplegic solution during canine mitral valve repair","authors":"K. Kurogochi , Y. Nii , A. Chen , M. Uechi","doi":"10.1016/j.jvc.2025.07.002","DOIUrl":"10.1016/j.jvc.2025.07.002","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Reperfusion ventricular fibrillation (VF) commonly occurs during open-heart surgery in dogs and humans. Pharmacological defibrillation using cardioplegia is a potential option; however, the standard technique remains unclear in dogs. We examined the clinical utility of pharmacological defibrillation in canine mitral valve repair.</div></div><div><h3>Animals, Materials, and Methods</h3><div>We retrospectively investigated 402 client-owned dogs that underwent mitral valve repair between January and December 2021.</div></div><div><h3>Results</h3><div>Ventricular fibrillation after cross-clamp release occurred in 70 of 397 cases (17.6%). Pharmacological defibrillation was attempted in 69 patients by administering 40 mEq/L potassium crystalloid cardioplegia via an aortic root catheter. If defibrillation was not achieved or VF recurred, the administration was repeated identically. In all cases, VF resolved after pharmacological defibrillation alone, without electrical defibrillation. Defibrillation was achieved with a single dose in 45 cases (median, 3.90 mL/kg; interquartile range [IQR], 2.95–4.95]), while multiple doses (range: 2–5) were necessary for 24 cases (median initial dose, 3.05 mL/kg [IQR, 2.07–4.14]). Predictors of reperfusion VF included body temperature at cross-clamp release (risk ratio, 0.82 per 1.0 °C) and pre-operative left ventricular internal dimension at end-diastole normalized to body weight (risk ratio, 1.11 per 0.1 unit).</div></div><div><h3>Study Limitations</h3><div>The retrospective nature of the study led to variability in personnel, absence of a control group, and limited data availability.</div></div><div><h3>Conclusions</h3><div>Reperfusion VF occurred in 17.6% of the canine mitral valve repair cases. Pharmacological defibrillation is a feasible option in such cases. Approximately 4.0 mL/kg of cardioplegia was effective for a single dose, whereas lower doses required multiple administrations.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"62 ","pages":"Pages 35-44"},"PeriodicalIF":1.3,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144889326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-26DOI: 10.1016/j.jvc.2025.07.004
J.C. Liu, J. Allen, K. Phipps, K. Barrett
An 11-week-old male intact Siamese cat was presented for evaluation of a grade V/VI parasternal systolic murmur. Echocardiography revealed multiple congenital cardiac abnormalities, including parallel orientation of the aorta and main pulmonary artery, a patent ductus arteriosus, and a juxta-arterial ventricular septal defect. Cardiac remodeling secondary to these congenital defects was also noted. The patient was clinically stable at the time of presentation, but the owner ultimately elected for humane euthanasia before the onset of cardiac decompensation. Postmortem necropsy was performed to confirm the congenital deformities identified on echocardiography. An ostium secundum atrial septal defect that was not originally detected on echocardiography was discovered at this time. The cat was diagnosed with a complete transposition of the great arteries and concurrent congenital defects that allowed for mixing of the pulmonary and systemic circulatory systems. This case report describes a congenital defect that is infrequently reported in veterinary medicine, as well as the utility of antemortem echocardiography and gross necropsy findings to characterize this deformity.
{"title":"Complete transposition of the great arteries with a patent ductus arteriosus, atrial septal defect, and juxta-arterial ventricular septal defect in a cat","authors":"J.C. Liu, J. Allen, K. Phipps, K. Barrett","doi":"10.1016/j.jvc.2025.07.004","DOIUrl":"10.1016/j.jvc.2025.07.004","url":null,"abstract":"<div><div>An 11-week-old male intact Siamese cat was presented for evaluation of a grade V/VI parasternal systolic murmur. Echocardiography revealed multiple congenital cardiac abnormalities, including parallel orientation of the aorta and main pulmonary artery, a patent ductus arteriosus, and a juxta-arterial ventricular septal defect. Cardiac remodeling secondary to these congenital defects was also noted. The patient was clinically stable at the time of presentation, but the owner ultimately elected for humane euthanasia before the onset of cardiac decompensation. Postmortem necropsy was performed to confirm the congenital deformities identified on echocardiography. An ostium secundum atrial septal defect that was not originally detected on echocardiography was discovered at this time. The cat was diagnosed with a complete transposition of the great arteries and concurrent congenital defects that allowed for mixing of the pulmonary and systemic circulatory systems. This case report describes a congenital defect that is infrequently reported in veterinary medicine, as well as the utility of antemortem echocardiography and gross necropsy findings to characterize this deformity.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"62 ","pages":"Pages 25-30"},"PeriodicalIF":1.3,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144878635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-15DOI: 10.1016/j.jvc.2025.07.001
A. Stout, F. Constantino-Casas, C. Partington
A nine-year-old, domestic shorthair cat was referred for investigation of a suspected renal mass, polyuria, polydipsia, hyporexia and weight loss of one month’s duration; no respiratory signs were reported. On presentation, the cat had marked respiratory effort. Thoracic auscultation revealed reduced heart and lung sounds bilaterally. Transthoracic echocardiography revealed a large pleural effusion and an extensive, homogenous mass within the right ventricular outflow tract, invading the pulmonary valve and causing severe infundibular and valvular pulmonary stenosis and right atrial and ventricular dilatation. The mass extended to, and infiltrated, the right ventricular free wall. Postmortem examination confirmed the presence of a mass associated with the pulmonary valve extending into the right ventricle and infiltrating the right ventricular and right atrial myocardium, resulting in severe infundibular and valvular pulmonary stenosis. Histopathology showed disseminated intermediate to large cell lymphoma affecting the kidney, myocardium, pulmonary valve, pancreas, diaphragm and adrenal glands.
{"title":"Cardiac lymphoma causing severe pulmonary stenosis in a cat","authors":"A. Stout, F. Constantino-Casas, C. Partington","doi":"10.1016/j.jvc.2025.07.001","DOIUrl":"10.1016/j.jvc.2025.07.001","url":null,"abstract":"<div><div>A nine-year-old, domestic shorthair cat was referred for investigation of a suspected renal mass, polyuria, polydipsia, hyporexia and weight loss of one month’s duration; no respiratory signs were reported. On presentation, the cat had marked respiratory effort. Thoracic auscultation revealed reduced heart and lung sounds bilaterally. Transthoracic echocardiography revealed a large pleural effusion and an extensive, homogenous mass within the right ventricular outflow tract, invading the pulmonary valve and causing severe infundibular and valvular pulmonary stenosis and right atrial and ventricular dilatation. The mass extended to, and infiltrated, the right ventricular free wall. Postmortem examination confirmed the presence of a mass associated with the pulmonary valve extending into the right ventricle and infiltrating the right ventricular and right atrial myocardium, resulting in severe infundibular and valvular pulmonary stenosis. Histopathology showed disseminated intermediate to large cell lymphoma affecting the kidney, myocardium, pulmonary valve, pancreas, diaphragm and adrenal glands.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 56-61"},"PeriodicalIF":1.3,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-03DOI: 10.1016/j.jvc.2025.06.008
F.D. Favier , G.C.M. Grinwis , A.H. Hulsman , M. den Toom , F.G. van Steenbeek , G. Santarelli
A three-year-old spayed female English Cocker spaniel was presented with diarrhea, abdominal distension, and exercise intolerance. On physical examination, bradycardia, abdominal distension with positive undulation, and a soft systolic right-sided heart murmur were detected. Electrocardiography showed a third-degree atrioventricular block with monomorphic idioventricular rhythm and premature ventricular ectopic beats. On echocardiography, an extremely thin right ventricular wall, severe right ventricular and atrial dilation, and severely depressed right ventricular systolic function were observed, and ascites was confirmed. Despite pacemaker implantation and standard treatment for congestive heart failure, the dog's condition deteriorated quickly, leading to euthanasia. Pathological examination showed a thin right ventricular free wall with fibrosis and largely absent cardiomyocytes, along with myocardial infiltration of adipocytes and lymphocytes. An arrhythmogenic cardiomyopathy complicated with a third-degree atrioventricular block was considered the most likely diagnosis.
{"title":"Third-degree atrioventricular block associated with suspected arrhythmogenic cardiomyopathy in a three-year-old Cocker Spaniel","authors":"F.D. Favier , G.C.M. Grinwis , A.H. Hulsman , M. den Toom , F.G. van Steenbeek , G. Santarelli","doi":"10.1016/j.jvc.2025.06.008","DOIUrl":"10.1016/j.jvc.2025.06.008","url":null,"abstract":"<div><div>A three-year-old spayed female English Cocker spaniel was presented with diarrhea, abdominal distension, and exercise intolerance. On physical examination, bradycardia, abdominal distension with positive undulation, and a soft systolic right-sided heart murmur were detected. Electrocardiography showed a third-degree atrioventricular block with monomorphic idioventricular rhythm and premature ventricular ectopic beats. On echocardiography, an extremely thin right ventricular wall, severe right ventricular and atrial dilation, and severely depressed right ventricular systolic function were observed, and ascites was confirmed. Despite pacemaker implantation and standard treatment for congestive heart failure, the dog's condition deteriorated quickly, leading to euthanasia. Pathological examination showed a thin right ventricular free wall with fibrosis and largely absent cardiomyocytes, along with myocardial infiltration of adipocytes and lymphocytes. An arrhythmogenic cardiomyopathy complicated with a third-degree atrioventricular block was considered the most likely diagnosis.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 51-55"},"PeriodicalIF":1.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-30DOI: 10.1016/j.jvc.2025.06.007
N Pereira, M Wyler
Introduction/objectives: Mitral annular disjunction (MAD) is common in humans and is associated with myxomatous mitral valve disease (MMVD), mitral valve prolapse, and arrhythmias. It is poorly described in dogs, and its prevalence is unknown. The objective of this study is to establish the prevalence of MAD in a population of dogs referred for cardiac examination.
Animals, methods and materials: A total of 415 dogs were screened. Over one year, dogs referred for cardiac assessment were prospectively enrolled. Age, breed, body weight, electrocardiography, and echocardiography were recorded. Dogs with systolic loss of continuity between the basal segment of the left ventricular posterior wall and the mitral valve (in right parasternal long-axis echocardiography) were considered to suffer from MAD.
Results: Four hundred three dogs were included in the study. Seven dogs exhibited MAD. All MAD dogs had MMVD. No normal dogs exhibited MAD. The overall prevalence of MAD was 1.7%. The prevalence of MAD in dogs with MMVD was 2.5%. The prevalence of MAD in dogs with mitral valve prolapse was also 2.5%. No MAD dogs exhibited arrhythmias. The presence of MAD was associated with lower body weight.
Study limitations: Single-operator bias and evolving diagnostic criteria for MAD in people complicate the interpretation of study results.
Conclusions: Mitral annular disjunction is uncommon in dogs referred for cardiac evaluation and could only be identified in dogs suffering from MMVD. No arrhythmias were found in MAD dogs.
{"title":"Mitral annular disjunction prevalence in 403 dogs referred for cardiac assessment (the MAD dog study).","authors":"N Pereira, M Wyler","doi":"10.1016/j.jvc.2025.06.007","DOIUrl":"https://doi.org/10.1016/j.jvc.2025.06.007","url":null,"abstract":"<p><strong>Introduction/objectives: </strong>Mitral annular disjunction (MAD) is common in humans and is associated with myxomatous mitral valve disease (MMVD), mitral valve prolapse, and arrhythmias. It is poorly described in dogs, and its prevalence is unknown. The objective of this study is to establish the prevalence of MAD in a population of dogs referred for cardiac examination.</p><p><strong>Animals, methods and materials: </strong>A total of 415 dogs were screened. Over one year, dogs referred for cardiac assessment were prospectively enrolled. Age, breed, body weight, electrocardiography, and echocardiography were recorded. Dogs with systolic loss of continuity between the basal segment of the left ventricular posterior wall and the mitral valve (in right parasternal long-axis echocardiography) were considered to suffer from MAD.</p><p><strong>Results: </strong>Four hundred three dogs were included in the study. Seven dogs exhibited MAD. All MAD dogs had MMVD. No normal dogs exhibited MAD. The overall prevalence of MAD was 1.7%. The prevalence of MAD in dogs with MMVD was 2.5%. The prevalence of MAD in dogs with mitral valve prolapse was also 2.5%. No MAD dogs exhibited arrhythmias. The presence of MAD was associated with lower body weight.</p><p><strong>Study limitations: </strong>Single-operator bias and evolving diagnostic criteria for MAD in people complicate the interpretation of study results.</p><p><strong>Conclusions: </strong>Mitral annular disjunction is uncommon in dogs referred for cardiac evaluation and could only be identified in dogs suffering from MMVD. No arrhythmias were found in MAD dogs.</p>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-17DOI: 10.1016/j.jvc.2025.06.006
I. Badric, N. Schreiber, M. Baron Toaldo
A 12-year-old, 19.8-kg, female neutered Nova Scotia Duck Tolling retriever was referred for investigation of a heart murmur. The dog was asymptomatic at the time of examination. On cardiac auscultation, a soft (2/6) diastolic heart murmur, louder at the left cardiac base, was present. Two-dimensional transthoracic echocardiography revealed a cyst-like structure attached to the aortic valve leaflets. Doppler examination showed that the cyst was fluid-filled and connected to the aortic and ventricular lumen. A moderate aortic valve insufficiency was also present. The left heart was mildly dilated. An echocardiography was repeated eight months later, and no relevant progression of the lesion was noted. The dog remained asymptomatic. An aortic cyst is an unusual congenital or acquired condition described in humans, but never reported previously in a dog.
{"title":"Echocardiographic findings of a valvular aortic cyst in a dog","authors":"I. Badric, N. Schreiber, M. Baron Toaldo","doi":"10.1016/j.jvc.2025.06.006","DOIUrl":"10.1016/j.jvc.2025.06.006","url":null,"abstract":"<div><div>A 12-year-old, 19.8-kg, female neutered Nova Scotia Duck Tolling retriever was referred for investigation of a heart murmur. The dog was asymptomatic at the time of examination. On cardiac auscultation, a soft (2/6) diastolic heart murmur, louder at the left cardiac base, was present. Two-dimensional transthoracic echocardiography revealed a cyst-like structure attached to the aortic valve leaflets. Doppler examination showed that the cyst was fluid-filled and connected to the aortic and ventricular lumen. A moderate aortic valve insufficiency was also present. The left heart was mildly dilated. An echocardiography was repeated eight months later, and no relevant progression of the lesion was noted. The dog remained asymptomatic. An aortic cyst is an unusual congenital or acquired condition described in humans, but never reported previously in a dog.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 36-40"},"PeriodicalIF":1.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144569984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-16DOI: 10.1016/j.jvc.2025.06.005
S. Shimano , K. Yamamoto , Y. Goto-Koshino , H. Tomiyasu , T. Mizuno
Introduction/Objectives
Surgical mitral valve repair is gaining recognition as an essential treatment option for dogs with myxomatous mitral valve disease despite the lack of established criteria for suture annuloplasty. Therefore, measuring normal mitral annular size in small-breed dogs without heart abnormalities may help determine the appropriate target annular size.
Animals, Materials and Methods
Dogs weighing <10 kg without evidence of heart disease that underwent three-phase computed tomography (CT) under anesthesia were retrospectively collected. Mitral annular measurements including trigone-to-trigone distance (TT) and the fourth thoracic vertebral body length (T4) were measured using multiplanar reformatting. The correlations between mitral annular measurements and body size, including body weight (BW) and T4, were examined. The regression equations for estimating annular circumference (AC) were then calculated.
Results
The study population comprised 248 dogs weighing 1.2–9.9 kg. Mean values (±standard deviation) of TT and AC were 1.56 (±0.27) and 5.81 (±0.95) cm, respectively. All annular measurements presented a correlation coefficient >0.7 with both BW and T4. Regression equations using BW, T4, and TT explained the AC in our population with sufficient coefficients of determination, with values of 0.68, 0.65, and 0.80, respectively.
Study Limitations
Synchronous electrocardiogram recordings were not available in this study, and the use of electrocardiogram-gated CT may provide a more accurate assessment.
Conclusions
Mitral annular size was strongly correlated with BW and T4 in small-breed dogs. A normal AC can be estimated through regression equations using BW, T4, or TT. The TT calculated using CT images is the most valuable index for accurate estimation.
{"title":"Measurement and estimation of normal mitral annular size using computed tomography in 248 small-breed dogs","authors":"S. Shimano , K. Yamamoto , Y. Goto-Koshino , H. Tomiyasu , T. Mizuno","doi":"10.1016/j.jvc.2025.06.005","DOIUrl":"10.1016/j.jvc.2025.06.005","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Surgical mitral valve repair is gaining recognition as an essential treatment option for dogs with myxomatous mitral valve disease despite the lack of established criteria for suture annuloplasty. Therefore, measuring normal mitral annular size in small-breed dogs without heart abnormalities may help determine the appropriate target annular size.</div></div><div><h3>Animals, Materials and Methods</h3><div>Dogs weighing <10 kg without evidence of heart disease that underwent three-phase computed tomography (CT) under anesthesia were retrospectively collected. Mitral annular measurements including trigone-to-trigone distance (TT) and the fourth thoracic vertebral body length (T4) were measured using multiplanar reformatting. The correlations between mitral annular measurements and body size, including body weight (BW) and T4, were examined. The regression equations for estimating annular circumference (AC) were then calculated.</div></div><div><h3>Results</h3><div>The study population comprised 248 dogs weighing 1.2–9.9 kg. Mean values (±standard deviation) of TT and AC were 1.56 (±0.27) and 5.81 (±0.95) cm, respectively. All annular measurements presented a correlation coefficient >0.7 with both BW and T4. Regression equations using BW, T4, and TT explained the AC in our population with sufficient coefficients of determination, with values of 0.68, 0.65, and 0.80, respectively.</div></div><div><h3>Study Limitations</h3><div>Synchronous electrocardiogram recordings were not available in this study, and the use of electrocardiogram-gated CT may provide a more accurate assessment.</div></div><div><h3>Conclusions</h3><div>Mitral annular size was strongly correlated with BW and T4 in small-breed dogs. A normal AC can be estimated through regression equations using BW, T4, or TT. The TT calculated using CT images is the most valuable index for accurate estimation.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 41-50"},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-12DOI: 10.1016/j.jvc.2025.06.003
L. Moretto , M. Dennler , N. Schreiber , M. Baron Toaldo
A six-year-old, neutered male, Airedale terrier with craniocerebral injury and shock after being hit by a car developed post-traumatic arrhythmia, which persisted after hemodynamic and neurological stabilization. Cardiac troponin I was markedly elevated. Transthoracic echocardiography and computed tomography angiography revealed an interventricular septal lesion, compatible with a myocardial splitting and intramural hematoma formation. The cardiac lesion resolved almost completely during the following weeks. About one year after initial presentation, the dog was referred with signs of right-sided congestive heart failure, thin and inhomogeneous interventricular septum, dilated cardiac chambers, and pulmonary artery, compatible with pulmonary hypertension, likely secondary to the left heart disease. Eventually the dog was euthanized due to poor response to medical therapy, approximately one year after his first decompensation. Interventricular septal hematomas are rare events in people, usually associated with cardiac surgery, trauma, or acute myocardial ischemia. This is the first dog described with a post-traumatic septal hematoma that has been extensively documented by means of echocardiography and cross-sectional imaging.
{"title":"Post-traumatic interventricular septal hematoma in a dog","authors":"L. Moretto , M. Dennler , N. Schreiber , M. Baron Toaldo","doi":"10.1016/j.jvc.2025.06.003","DOIUrl":"10.1016/j.jvc.2025.06.003","url":null,"abstract":"<div><div>A six-year-old, neutered male, Airedale terrier with craniocerebral injury and shock after being hit by a car developed post-traumatic arrhythmia, which persisted after hemodynamic and neurological stabilization. Cardiac troponin I was markedly elevated. Transthoracic echocardiography and computed tomography angiography revealed an interventricular septal lesion, compatible with a myocardial splitting and intramural hematoma formation. The cardiac lesion resolved almost completely during the following weeks. About one year after initial presentation, the dog was referred with signs of right-sided congestive heart failure, thin and inhomogeneous interventricular septum, dilated cardiac chambers, and pulmonary artery, compatible with pulmonary hypertension, likely secondary to the left heart disease. Eventually the dog was euthanized due to poor response to medical therapy, approximately one year after his first decompensation. Interventricular septal hematomas are rare events in people, usually associated with cardiac surgery, trauma, or acute myocardial ischemia. This is the first dog described with a post-traumatic septal hematoma that has been extensively documented by means of echocardiography and cross-sectional imaging.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"61 ","pages":"Pages 29-35"},"PeriodicalIF":1.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144548615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}