Journal of Veterinary Cardiology最新文献_第10页

Valvular mitral stenosis in adult cats: knowledge gained from the clinical and pathological workup of 18 cases 成年猫二尖瓣狭窄：从18例临床和病理检查中获得的知识

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-06-01 Epub Date: 2025-04-01 DOI: 10.1016/j.jvc.2025.03.006

N. Schreiber , F. Prisco , A. Kipar , L. Schurna , M. Tursi , M.B. Toaldo

Introduction/objectives

Feline valvular mitral stenosis (VMS) is uncommonly reported. The aim of this study was to describe diagnostic and clinicopathological characteristics of VMS in adult cats.

Animals, Materials and Methods

Eighteen client-owned cats were included in this study. A retrospective observational study. Clinical records were searched based on echocardiography. Data regarding clinical, laboratory, echocardiographic findings, outcome, and, in four cats, gross postmortem images of the heart were reviewed, and histological examinations performed.

Results

Most cats were non-pedigree (11/18), with a median age of 13.2 years. Congestive heart failure was common (15/18). Three cats had hypertrophic cardiomyopathy phenotype, including one with transient myocardial thickening. Concomitant hyperthyroidism (9/18) was frequent. In one cat, echocardiography performed one year earlier did not show any changes. Upon echocardiography, all 18 cats had characteristic hockey-stick appearance of the anterior leaflet and narrow turbulent diastolic flow across the mitral valve. Twelve cats had fused diastolic transmitral waves, with a median velocity of 0.54 m/s (0.71–3.24 m/s). The remaining six had a median peak velocity of the early and late-diastolic transmitral waves of 1.3 m/s (0.95–2.8 m/s) and 0.99 m/s (0.65–2.05 m/s), respectively. Eleven cats had died, 10 of cardiac death (median survival time: 366 days). Macroscopically, the mitral valve leaflets appeared thickened and distorted, and the surrounded ventricular endocardium thickened. Histology revealed marked endocardial fibrosis of the mitral valve and surrounding ventricular endocardium, dominated by type I collagen.

Conclusions

The most striking finding is the documented acquirement of VMS in one cat, while the acquired nature of the lesion could not be confirmed in the other cases. The pathological findings are compatible with a chronic remodeling process that results in marked endocardial fibrosis in four cats.

简介/目的猫二尖瓣狭窄（VMS）是罕见的报道。本研究的目的是描述成年猫VMS的诊断和临床病理特征。动物、材料和方法本研究共纳入18只客户养猫。回顾性观察性研究。根据超声心动图检索临床记录。我们回顾了4只猫的临床、实验室、超声心动图结果、结果以及大体死后心脏图像，并进行了组织学检查。结果大多数猫是非纯种猫（11/18），中位年龄为13.2岁。充血性心力衰竭较为常见（15/18）。三只猫有肥厚型心肌病表型，其中一只有短暂性心肌增厚。合并甲状腺功能亢进（9/18）较为常见。在一只猫中，一年前进行的超声心动图没有显示任何变化。超声心动图显示，所有18只猫的前小叶呈典型的曲棍球棒状，二尖瓣舒张血流狭窄。12只猫的舒张透射波融合，平均速度为0.54 m/s （0.71-3.24 m/s）。其余6例舒张早期和晚期透射波的中位峰值速度分别为1.3 m/s （0.95 ~ 2.8 m/s）和0.99 m/s （0.65 ~ 2.05 m/s）。11只猫死亡，10只心源性死亡（中位生存时间：366天）。宏观上，二尖瓣小叶增厚变形，周围心室心内膜增厚。组织学显示二尖瓣及周围心室心内膜明显纤维化，以I型胶原为主。结论最显著的发现是在1只猫中记录了VMS的获得性，而在其他病例中无法确认病变的获得性。病理结果与导致4只猫显著心内膜纤维化的慢性重塑过程相一致。

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引用次数: 0

Idiopathic spontaneous intracardiac microbubbles in an adult dog 成年犬的特发性自发性心内微泡

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-06-01 Epub Date: 2025-03-12 DOI: 10.1016/j.jvc.2025.03.001

L. Beeby , M. Martinez , E.F. Bode

A four-year-old, female neutered English springer spaniel presented for evaluation of exercise intolerance, panting and lingual cyanosis. Echocardiography revealed a structurally and functionally normal heart with the presence of spontaneous intracardiac microbubbles entering the right side of the heart from the caudal vena cava. A cause for the clinical signs could not be identified; routine blood work, urinalysis and electrocardiography were unremarkable. Testing for tick-borne diseases, clotting times, cardiac biomarkers, thyroid function and basal cortisol were all within normal limits. Faecal samples tested for Clostridium perfringens alpha, beta and epsilon toxins were negative. Genetic conditions including malignant hyperthermia and phosphofructokinase deficiency were excluded. Computed tomography and angiography of the abdomen and thorax revealed no abnormalities or shunting vessels that could explain the origin of the spontaneous intracardiac microbubbles. Previously, microbubbles have only been visualised when intravenous access is present or when purposeful contrast studies are performed. As far as the authors are aware, this is the first case of spontaneous intracardiac microbubbles visualised in the right heart of a dog with no identifiable underlying systemic conditions.

一只四岁，雌性绝育的英国施普林格西班牙猎犬提出评估运动不耐受，喘气和舌紫。超声心动图显示心脏结构和功能正常，存在从尾腔静脉进入心脏右侧的自发心内微泡。临床症状的原因无法确定；血常规、尿常规、心电图无明显异常。蜱传疾病、凝血时间、心脏生物标志物、甲状腺功能和基础皮质醇的检测均在正常范围内。粪便样本的产气荚膜梭菌α、β和epsilon毒素检测均为阴性。排除了包括恶性高热和磷酸果糖激酶缺乏在内的遗传条件。腹部和胸部的计算机断层扫描和血管造影显示没有异常或分流血管可以解释自发性心内微泡的起源。以前，微泡仅在静脉注射或有目的的对比研究时可见。据作者所知，这是第一例在没有可识别的潜在系统疾病的狗的右心出现自发性心内微泡的病例。

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引用次数: 0

Antidiuretic hormone concentrations in dogs with heart disease and relationship to serum chloride 心脏病犬抗利尿激素浓度与血清氯化物的关系

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-06-01 Epub Date: 2025-01-31 DOI: 10.1016/j.jvc.2025.01.007

A.N. Harris , C. Hanner, A. Cooper, R.A. Castro, D.B. Adin

Introduction/objectives

Non-osmotic antidiuretic hormone (ADH) release promotes electrolyte-free water retention in dogs with congestive heart failure (CHF), contributing to low electrolyte concentrations. We hypothesized that dogs with CHF would have higher ADH concentrations than healthy dogs and dogs with preclinical heart disease, and that ADH concentrations would positively correlate to the amount of chloride [Cl⁻] correction but not serum osmolality.

Animals, Materials and Methods

The study population comprised 20 healthy, 20 preclinical, and 20 CHF dogs. Serum electrolytes, serum osmolality, and plasma ADH were measured and compared between groups using the Kruskal–Wallis test. Relationships between ADH and electrolytes, the amount of [Cl⁻] correction, osmolality, and the use of amlodipine and renin-angiotensin-aldosterone system inhibitors were explored with multiple linear regression.

Results

Preclinical (median 6.5 pg/mL; range 1.8 pg/mL–33.8 pg/mL) and CHF (6.7 pg/mL; range 2.0 pg/mL–28.1 pg/mL) dogs had higher ADH concentrations than healthy dogs (median 3.4 pg/mL; range 0.1 pg/mL–6.2 pg/mL) (P=0.004) but there was no difference between preclinical and CHF dogs. Serum ADH was inversely correlated with [Cl⁻] (P=0.026, r_s = −0.287) and c[Cl⁻] (P=0.008, r_s = −0.338). Amlodipine use and [Cl⁻] predicted ADH after controlling for age, weight, use of renin-angiotensin aldosterone inhibitors, and osmolality. There was no significant relationship between ADH and the amount of [Cl⁻] correction, osmolality, or serum sodium.

Discussion

The inverse relationship between ADH and serum [Cl⁻] and the positive relationship with amlodipine use suggests neurohormonal stimulation as a common mechanism.

Uncoupling of ADH from osmolality and serum sodium is consistent with non-osmotic release, which was present even in dogs with preclinical heart disease.

Conclusions

Antidiuretic hormone was elevated in dogs with heart disease but was not a unique feature of advanced heart disease.

非渗透性抗利尿激素（ADH）的释放促进充血性心力衰竭（CHF）犬的无电解质水潴留，导致电解质浓度降低。我们假设患有CHF的狗的ADH浓度高于健康狗和患有临床前心脏病的狗，并且ADH浓度与氯离子[Cl−]校正量呈正相关，而与血清渗透压无关。动物、材料和方法研究人群包括20只健康犬、20只临床前犬和20只CHF犬。采用Kruskal-Wallis试验测定血清电解质、血清渗透压和血浆ADH，并比较各组之间的差异。通过多元线性回归探讨ADH与电解质、[Cl−]校正量、渗透压以及氨氯地平和肾素-血管紧张素-醛固酮系统抑制剂的使用之间的关系。结果临床前期(中位6.5 pg/mL；范围1.8 pg/mL - 33.8 pg/mL)和CHF (6.7 pg/mL；范围2.0 pg/mL - 28.1 pg/mL)，狗的ADH浓度高于健康狗(中位数3.4 pg/mL；范围0.1 pg/mL - 6.2 pg/mL) (P=0.004)，但临床前和CHF犬之间无差异。血清ADH与[Cl−]（P=0.026, rs = - 0.287）、c[Cl−]（P=0.008, rs = - 0.338）呈负相关。在控制年龄、体重、使用肾素-血管紧张素醛固酮抑制剂和渗透压后，氨氯地平的使用和[Cl−]预测ADH。ADH与[Cl−]校正量、渗透压或血清钠之间无显著关系。ADH与血清[Cl−]呈负相关，与氨氯地平使用呈正相关，提示神经激素刺激是ADH的共同机制。ADH与渗透压和血清钠的解耦与非渗透性释放一致，即使在患有临床前心脏病的狗中也存在这种情况。结论利尿激素在心脏病犬中升高，但不是晚期心脏病犬的特有特征。

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引用次数: 0

Multimodal imaging of congenital double-inlet left ventricle with hypoplastic right ventricle and ventricular septal defect in a young cat 幼猫先天性双入口左心室伴右心室发育不全及室间隔缺损的多模态成像

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-06-01 Epub Date: 2025-01-25 DOI: 10.1016/j.jvc.2025.01.005

O. Peterson, M. Pabon Torres, R. White, E. Manson, M. Tropf, J.L. Ward

Double-inlet left ventricle (DILV) is a rare congenital cardiac abnormality that is a subtype of univentricular congenital disease. This defect has been reported in people and large animals but has not been previously described in a small animal. Here, we report a one-year-old cat diagnosed with DILV accompanied by a hypoplastic right ventricle and ventricular septal defect. Complete echocardiography, fluoroscopy with non-selective angiography, and computed tomography with angiography were used to document and characterize this rare case presentation. Findings in this patient showed similarities to previously documented cases of DILV in a calf and foal and were most consistent with type I Holmes classification of DILV in people.

双入口左心室（DILV）是一种罕见的先天性心脏异常，是单心室先天性疾病的一个亚型。这种缺陷在人类和大型动物中已有报道，但在小动物中尚未见报道。在这里，我们报告一只一岁大的猫被诊断为DILV并伴有右心室发育不全和室间隔缺损。完整的超声心动图、非选择性血管造影的透视和血管造影的计算机断层扫描被用来记录和描述这个罕见的病例。该患者的发现与先前记录的小牛和马驹DILV病例相似，并且与人类DILV的I型Holmes分类最一致。

引用次数: 0

Intra-operative use of transesophageal echocardiography in dogs undergoing interventional procedures for pulmonic stenosis: a case series 在接受肺动脉狭窄介入手术的犬只术中使用经食道超声心动图：一个病例系列

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-06-01 Epub Date: 2025-02-10 DOI: 10.1016/j.jvc.2025.02.001

S. Sudunagunta, S. Goodrich, F. Sarcinella

Six dogs were presented for interventional treatment of pulmonic stenosis (balloon valvuloplasty or pulmonary stent implantation). Intra-operative transesophageal echocardiography was performed for subjective pulmonary valve assessment and to measure the transpulmonary pressure gradient. Balloon valvuloplasty was performed in two dogs; the remaining four dogs underwent pulmonary stent implantation. The reduction in pressure was assessed after balloon inflation/stent deployment by right heart catheterization and transesophageal echocardiography. In two patients, complete catheterization was not performed, and success was based solely on a reduction in the pressure gradient measured by transesophageal echocardiography. The procedure was completed successfully in all six dogs, with reduction in pressure measured by catheterization ranging from 47.0% to 96.8% (median: 78.6%) in four dogs and 47.3%–85.2% (median: 80.9%) measured by transesophageal echocardiography in all six dogs. No complications associated with transesophageal echocardiography were observed. In this case series, transesophageal echocardiography allowed subjective assessment of the pulmonic valve leaflets and measurement of annular diameter and transpulmonary pressure gradient. The reduction in transpulmonary pressure gradient seen with transesophageal echocardiography was comparable to the reduction documented on catheterization. Further studies are indicated to objectively assess the agreement between transesophageal echocardiography and catheterization measurements, but in these patients, transesophageal echocardiography allowed increased confidence in procedural success.

本文介绍了6只狗进行肺动脉狭窄的介入治疗（球囊瓣膜成形术或肺支架植入术）。术中行经食管超声心动图对肺动脉瓣进行主观评估，并测量经肺压力梯度。2只犬行球囊瓣膜成形术；其余4只狗接受了肺支架植入。通过右心导管和经食管超声心动图评估球囊膨胀/支架置入后压力的降低。在两名患者中，没有进行完全的导管置入，成功仅仅是基于经食管超声心动图测量的压力梯度的降低。所有6只狗都成功完成了手术，4只狗通过导管测量的压力降低了47.0%至96.8%（中位数：78.6%），6只狗通过经食管超声心动图测量的压力降低了47.3%至85.2%（中位数：80.9%）。经食管超声心动图检查无并发症。在本病例系列中，经食管超声心动图可以对肺动脉瓣小叶进行主观评估，并测量肺动脉环直径和经肺压力梯度。经食管超声心动图显示的经肺压力梯度的降低与导管置入术记录的降低相当。进一步的研究表明，客观地评估经食管超声心动图和导管测量之间的一致性，但在这些患者中，经食管超声心动图增加了手术成功的信心。

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引用次数: 0

Ventricular tachycardia as the main manifestation of primary cardiac lymphoma in a dog 犬原发性心脏淋巴瘤的主要表现为室性心动过速

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-04-01 Epub Date: 2025-01-21 DOI: 10.1016/j.jvc.2025.01.003

G. Romito , L. Marconato , M.E. Turba , M. Morini

An 11-year-old cocker spaniel was referred with a one-day history of lethargy. Upon presentation, cardiac auscultation revealed a tachyarrhythmia. Two-dimensional transthoracic echocardiography with concurrent electrocardiographic tracing showed biventricular systolic dysfunction, mild left atrial dilation, functional mitral and tricuspid regurgitations, and sustained wide-complex monomorphic tachycardia (heart rate: 330 beats per minute), primarily consistent with ventricular tachycardia. Laboratory test results were unremarkable, except for an elevated serum concentration of cardiac troponin I (2.84 ng/mL). Initially, despite the intravenous administration of lidocaine and esmolol, cardioversion was not achieved. Oral amiodarone was subsequently added to the antiarrhythmic protocol, resulting in the restoration of sinus rhythm, followed by an improvement in the dog's clinical condition and biventricular systolic function on repeated echocardiographic examination. Accordingly, the dog was discharged from the hospital on amiodarone therapy. However, four days later, the dog returned with a relapse of symptomatic ventricular tachycardia. Despite prompt management, the dog succumbed to the progression of ventricular tachycardia into ventricular fibrillation. Interestingly, although repeated echocardiographic examinations did not reveal abnormalities suggesting a cardiac tumor, macroscopic and histological findings led to the diagnosis of primary cardiac lymphoma of T-cell origin. This case contributes to the currently limited scientific literature on primary cardiac lymphoma in dogs. Moreover, it contributes to raising awareness among veterinary cardiologists about the potential limitations of two-dimensional transthoracic echocardiography in detecting cardiac lymphoma in dogs, as well as the possible arrhythmogenic role of this rare condition in the species.

一只11岁的可卡犬有一天嗜睡的病史。经心脏听诊发现心律失常。经胸二维超声心动图并发心电图示双室收缩功能不全，左心房轻度扩张，二尖瓣和三尖瓣功能性反流，持续宽复单型心动过速（心率：330次/分钟），与室性心动过速基本一致。除了心肌肌钙蛋白I血清浓度升高（2.84 ng/mL）外，实验室检查结果无显著差异。最初，尽管静脉给予利多卡因和艾司洛尔，但没有实现心律转复。随后在抗心律失常方案中加入口服胺碘酮，导致窦性心律恢复，随后狗的临床状况和双心室收缩功能在重复超声心动图检查中有所改善。因此，这只狗在接受胺碘酮治疗后出院。然而，4天后，狗再次出现症状性室性心动过速。尽管及时处理，狗屈服于室性心动过速进展为心室颤动。有趣的是，尽管多次超声心动图检查未发现提示心脏肿瘤的异常，但宏观和组织学检查结果导致诊断为原发性t细胞源性心脏淋巴瘤。本病例为目前有限的关于犬原发性心脏淋巴瘤的科学文献做出了贡献。此外，它有助于提高兽医心脏病学家对二维经胸超声心动图检测犬心脏淋巴瘤的潜在局限性的认识，以及这种罕见疾病在犬类中可能的致心律失常作用。

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引用次数: 0

Quantitative methods for evaluation of mitral regurgitation severity in canine degenerative mitral valve disease 犬退行性二尖瓣病变二尖瓣反流严重程度的定量评价方法

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-04-01 Epub Date: 2025-01-10 DOI: 10.1016/j.jvc.2025.01.002

B. Del Nero, B.M. Potter, L.C. Visser, B.A. Scansen, E.C. Orton

Introduction/objectives

Quantitative assessment of mitral regurgitation (MR) severity has become increasingly important as procedural therapies for MR reduction become available. This study aimed to obtain quantitative measures of MR severity across stages of degenerative mitral valve disease (DMVD) and evaluate agreement between two echocardiographic methods.

Animals, materials and methods

Fifty-one client-owned dogs were included across three DMVD stages (ACVIM B1, B2, and C). Regurgitant volume (RVol) and fraction (RF) were measured on echocardiograms prospectively acquired by a single cardiologist using volumetric (using Simpson's method of discs) and proximal isovelocity surface area (PISA) methods. Results were compared across stages. Agreement between methods over the range of MR severity was determined by Bland–Altman analyses. Intra- and inter-observer measurement variability assessments were performed via intraclass correlation coefficients (ICC).

Results

Median differences (25th percentile, 75th percentile) for volumetric and PISA-derived RVol and RF were as follows, respectively: B1:0.19 mL/kg (−0.02 mL/kg, 0.25 mL/kg), 13.6% (−2.17%, 20.6%); B2:1.49 mL/kg (1.09 mL/kg, 2.12 mL/kg), 55.6% (45.0%, 70.5%); C:2.72 mL/kg (1.76 mL/kg, 3.13 mL/kg), 67.2% (61.8%, 78.5%); B1:0.39 mL/kg (0.22 mL/kg, 0.69 mL/kg), 34.3% (19.0%, 56.1%); B2:1.67 mL/kg (1.33 mL/kg, 2.15 mL/kg), 58.8% (49.8%, 73.9%); C:3.1 mL/kg (1.91 mL/kg, 3.57 mL/kg), 75.2% (66.4%, 92.0%). All were different (P<0.0001) across stages. There was no proportional bias for RVol or RF (P=0.79, P=54). Intra- and inter-observer variability assessments showed ICC greater than 0.75 except PISA RF.

Conclusions

Measures of MR severity correlate with disease stage, although their accuracy remains unknown. Volumetric and PISA methods are not interchangeable.

随着二尖瓣返流（MR）降低的程序性治疗的出现，对其严重程度的定量评估变得越来越重要。本研究旨在获得退行性二尖瓣疾病（DMVD）各阶段MR严重程度的定量测量，并评估两种超声心动图方法之间的一致性。动物、材料和方法51只客户拥有的狗分为三个DMVD阶段（ACVIM B1、B2和C）。在超声心动图上测量反流体积（RVol）和分数（RF），这些超声心动图是由一名心脏病专家使用容积法（使用辛普森圆盘法）和近端等速度表面积（PISA）方法前瞻性地获得的。各阶段的结果比较。通过Bland-Altman分析确定了不同方法在MR严重程度范围内的一致性。通过类内相关系数（ICC）对观察者内部和观察者之间的测量变异性进行评估。结果容积法和pisa法RVol和RF的中位数差异（25百分位数，75百分位数）分别为：B1:0.19 mL/kg (- 0.02 mL/kg, 0.25 mL/kg), 13.6% (- 2.17%, 20.6%)；B2:1.49 mL / kg(1.09毫升/公斤,2.12毫升/公斤),55.6% (45.0%,70.5%);C: 2.72毫升/公斤(1.76毫升/公斤,3.13毫升/公斤),67.2% (61.8%,78.5%);B1:0.39 mL / kg(0.22毫升/公斤,0.69毫升/公斤),34.3% (19.0%,56.1%);B2:1.67 mL / kg(1.33毫升/公斤,2.15毫升/公斤),58.8% (49.8%,73.9%);C: 3.1毫升/公斤(1.91毫升/公斤,3.57毫升/公斤),75.2%(66.4%,92.0%)。各个阶段的结果都不同（P<0.0001）。RVol和RF均无比例偏倚（P=0.79， P=54）。观察者内部和观察者之间的变异性评估显示，除PISA RF外，ICC大于0.75。结论MR严重程度的测量与疾病分期相关，尽管其准确性尚不清楚。容积法和PISA方法是不可互换的。

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引用次数: 0

High-density versus point-by-point electroanatomical activation mapping of a cranial vena cava tachycardia in a dog 狗颅腔静脉心动过速的高密度与逐点电解剖激活图谱。

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-04-01 Epub Date: 2024-12-07 DOI: 10.1016/j.jvc.2024.12.002

S. Siess , L.L. Santistevan , R.A. Santilli , W. Hsue

A seven-year-old, male intact Newfoundland was referred for catheter ablation of supraventricular tachycardia. Activation mapping was performed using an electroanatomical mapping system to visualize the activation wavefront in a color-coded fashion on an anatomical shell. Atrial flutter with an early-meets-late signal (i.e., suspected isthmus) at the cranial vena cava was most suspected, but could not be targeted due to overlap with the phrenic nerve. On follow-up, a more complete high-density map better outlined the suspected circuit and substrate of cranial vena cava flutter. Compared to point-by-point catheters, high-density mapping catheters enhance identification and annotation of low-amplitude electrogram signals.

一个七岁的男性完整的纽芬兰犬被转诊为室上性心动过速的导管消融。使用电解剖作图系统进行激活作图，以在解剖壳上以颜色编码的方式可视化激活波前。心房扑动在颅腔静脉出现早-晚信号（即疑似峡部）是最可疑的，但由于与膈神经重叠而无法定位。在随访中，一个更完整的高密度地图更好地勾勒出疑似颅内腔静脉颤振的电路和基底。与逐点导尿管相比，高密度导尿管增强了对低振幅电图信号的识别和注释。

引用次数: 0

Congenital isolated left ventricular non-compaction in two juvenile dogs 两只幼年犬先天性孤立性左心室不压实。

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-04-01 Epub Date: 2024-12-10 DOI: 10.1016/j.jvc.2024.12.003

D. Ma , M. Singh , N. Stander

Two juvenile (five- and 10-month-old), male, neutered, Jack Russel terrier cross dogs, each presented primarily for respiratory signs of varying severity, were included in the study. The first presented for coughing and weakness, and the other presented in respiratory distress. A cardiac murmur was absent in both. Imaging findings were strikingly similar for both dogs. Thoracic radiography revealed severe, disproportionate left atrial dilation with otherwise normal cardiac silhouette shape and size. Echocardiography revealed severe left ventricular mural thickening with hypertrabeculation and marked left atrial enlargement consistent with a diagnosis of congenital, isolated left ventricular non-compaction. Both dogs deteriorated clinically and were humanely euthanised without necropsy.

研究中包括两只幼年（5个月和10个月），雄性，绝育的杰克罗素梗杂交狗，每只狗主要表现为不同严重程度的呼吸症状。第一个表现为咳嗽和虚弱，另一个表现为呼吸窘迫。两例患者均无心脏杂音。两只狗的成像结果惊人地相似。胸片显示严重的，不成比例的左心房扩张，其他方面心脏轮廓形状和大小正常。超声心动图显示严重的左心室壁增厚伴小梁亢进和明显的左心房增大，与先天性孤立性左心室不致密的诊断一致。两只狗在临床上病情恶化，在没有尸检的情况下被人道安乐死。

引用次数: 0

Pre-excitation alternans in a cat 猫的预激交替。

IF 1.5 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-04-01 Epub Date: 2024-12-14 DOI: 10.1016/j.jvc.2024.12.004

L.A. Murphy , R.K. Nakamura

A nine-year-old male neutered domestic shorthair cat presented on referral for evaluation. The cat presented to its primary veterinarian for acute onset vomiting, panting, and weakness. An electrocardiogram performed at the regular veterinarian was concerning for ventricular tachycardia, and the cat was referred for further evaluation. An echocardiogram revealed hypertrophic cardiomyopathy, and a review of the electrocardiogram revealed findings suggestive of ventricular pre-excitation alternans with the suspect pre-excited complexes appearing to alternate with sinus complexes. This is the first reported case of pre-excitation alternans in a cat.

一只九岁的雄性绝育家养短毛猫被介绍来接受评估。这只猫因急性呕吐、喘气和虚弱而就诊于其初级兽医。在常规兽医处进行的心电图涉及室性心动过速，猫被转诊作进一步评估。超声心动图显示肥厚性心肌病，复查心电图显示心室预兴奋交替，可疑的预兴奋复合体与窦性复合体交替。这是首次报道的猫的预激交替。

引用次数: 0