Journal of Veterinary Cardiology最新文献_第4页

Journal title page and editorial board 杂志标题页和编辑委员会

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 DOI: 10.1016/S1760-2734(25)00123-7

引用次数: 0

Retrospective review of the use of hydrochlorothiazide in dogs with myxomatous mitral valve disease and refractory congestive heart failure (American College of Veterinary Cardiology stage D) 氢氯噻嗪用于二尖瓣黏液瘤性疾病和难治性充血性心力衰竭犬的回顾性研究（美国兽医心脏病学会D期）。

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-09-28 DOI: 10.1016/j.jvc.2025.09.005

A. Boscia , A. Galizzi , M. Caccia , V. Caroli , G. Ortiz Diez , R. Toschi Corneliani , I. Spalla

Introduction/Objectives

In dogs with myxomatous mitral valve disease (MMVD) American College of Veterinary Internal Medicine (ACVIM) stage D, hydrochlorothiazide (HCTZ) can be added to achieve sequential nephron blockade. Information on outcome, survival, and complications in this group of patients receiving HCTZ is limited, hence the aim of the present retrospective observational, longitudinal study.

Animals, Materials and Methods

A single-referral-center cohort study was conducted; 25 dogs diagnosed with MMVD stage D receiving HCTZ as part of multimodal treatment of refractory congestive heart failure were included in the study. Data retrieved included cardiac treatment at T0 (when HCTZ was first prescribed) and subsequent visits, available bloodwork, echocardiographic assessment, additional diagnostics, cause of death, and survival time.

Results

Mean starting dose of HCTZ was 0.8 mg/kg every 48 h, with progressive increases (latest mean recorded HCTZ dose: 1.5 mg/kg/day). Azotemia was identified in three dogs at T0 and in 11 dogs following HCTZ addition. Three dogs experienced clinically relevant side effects, resulting in discontinuation of HCTZ in one dog. Twenty dogs died, the majority due to cardiac disease (90). Median survival time of the cohort was 268 days.

Study Limitations

Limitations of this study included the retrospective nature of the study and small sample size.

Conclusions

Although associated with an increase in renal parameters, HCTZ addition at the study dosages appeared clinically tolerated in most dogs with MMVD ACVIM stage D, with a prolonged median survival time for dogs in ACVIM stage D.

简介/目的：在美国兽医内科学会（ACVIM） D期二尖瓣黏液瘤病（MMVD）犬中，可添加氢氯噻嗪（HCTZ）以实现肾素序贯阻断。关于这组接受HCTZ患者的预后、生存和并发症的信息有限，因此本研究的目的是回顾性观察性、纵向研究。动物、材料和方法：采用单转诊中心队列研究；25只被诊断为MMVD D期的狗接受HCTZ作为难治性充血性心力衰竭多模式治疗的一部分纳入研究。检索到的数据包括T0时（首次开HCTZ时）的心脏治疗和随后的就诊、可用的血液检查、超声心动图评估、其他诊断、死亡原因和生存时间。结果：HCTZ平均起始剂量为0.8 mg/kg/ h，并逐渐增加（最新记录的HCTZ平均剂量为1.5 mg/kg/d）。3只狗在T0和11只狗在添加HCTZ后发现氮血症。3只狗出现了临床相关的副作用，导致1只狗停止使用HCTZ。20只狗死亡，大多数死于心脏病（90只）。该队列的中位生存时间为268天。研究局限性：本研究的局限性包括研究的回顾性和小样本量。结论：尽管与肾脏参数增加相关，但在研究剂量下添加HCTZ在大多数患有MMVD ACVIM D期的狗中表现出临床耐受性，并且ACVIM D期狗的中位生存时间延长。

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引用次数: 0

Incidentally identified aortic dissection in a Great Pyrenees dog 偶然发现了一只大比利牛斯犬的主动脉夹层

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-09-30 DOI: 10.1016/j.jvc.2025.09.007

H. Melhorn , M. Sha , M. Kurihara , K. Megquier , R. Aronson , V. Yang

A two-year-old female spayed Great Pyrenees dog was presented for an echocardiogram after a dilated aortic root and ascending aorta were found on a routine echocardiogram examination one year prior. A suspected aortic dissection was detected on the recheck echocardiogram, which was confirmed with cardiac magnetic resonance imaging. Subsequent genetic sequencing confirmed nucleotide variants of several connective tissue– associated proteins, of which three are known to be associated with connective tissue disorders in humans, including ADAMTS3, ADAMTSL2, and SMAD4. The dog was subclinical at the time of examination and has since been doing well with medical management on carvedilol and exercise restriction.

一年前，一只两岁的雌性大比利牛斯犬在常规超声心动图检查中发现主动脉根和升主动脉扩张后，进行了超声心动图检查。复查超声心动图发现疑似主动脉夹层，经心脏磁共振成像证实。随后的基因测序证实了几种结缔组织相关蛋白的核苷酸变异，其中三种已知与人类结缔组织疾病相关，包括ADAMTS3、ADAMTSL2和SMAD4。这只狗在检查时是亚临床症状，此后在卡维地洛和运动限制的医疗管理下表现良好。

引用次数: 0

Echocardiographic description of shunt volume in dogs with patent ductus arteriosus 动脉导管未闭犬分流容积的超声心动图描述。

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-09-08 DOI: 10.1016/j.jvc.2025.09.001

L.S. Köster , A.B. Asbury , C.M. Springer

Introduction/Objectives

Patent ductus arteriosus (PDA) can have a variable clinical course. The aims of this study were to describe Doppler estimates of shunt volume and their association with clinical and echocardiographic abnormalities.

Animals, Materials and Methods

Dogs with a diagnosis of a PDA on echocardiography were included in this study. Signalment, clinical signs, Doppler estimates of shunt volume, and outcome were collected from medical records (June 2020 and 2023) and examined for statistical associations. Groups included hemodynamically insignificant, incidental left-to-right (LR) shunt, left-to-right shunt with congestive heart failure (LCHF), and pulmonary hypertension (PH).

Results

Most dogs had standard LR shunts (76%), 4/4 heart murmur (69%), closing Doppler pattern characterized by—continuous LR shunting and high velocity (71%), and a color flow Doppler pattern—extending to the pulmonic valve (51%). Larger left ventricular chambers and normalized color flow Doppler width (CFDw) (P=0.023) were found in clinical as compared to asymptomatic dogs. Transmitral peak E (E), left ventricular outflow tract velocities, and color flow Doppler pixilation percent fill of the main pulmonary artery (CFD%) were correlated with left chamber dimensions. The LCHF group had a larger CFDw than the LR shunt group (P=0.009), which in turn was larger than that of the PH group (P=0.004). The mean CFD% was larger in the LCHF group (P=0.008) than in the LR-shunt group.

Study Limitations

The retrospective data collection limited standardization of image acquisition. Applicability is further limited by lack of intra-observer and interobserver variability analyses.

Conclusions

Doppler measures of shunt volume in dogs with PDA include E- and left ventricular outflow tract velocities, CFDw, and CFD%.

简介/目的：动脉导管未闭（PDA）有不同的临床病程。本研究的目的是描述多普勒估计分流容量及其与临床和超声心动图异常的关系。动物、材料和方法：本研究纳入超声心动图诊断为PDA的犬。从医疗记录（2020年6月和2023年6月）中收集信号、临床体征、分流体积的多普勒估计和结果，并检查统计关联。各组包括血流动力学不显著、偶发左向右分流、左向右分流合并充血性心力衰竭（LCHF）和肺动脉高压（PH）。结果：大多数狗有标准的左左分流（76%），4/4心脏杂音（69%），以连续左左分流和高流速为特征的闭合多普勒模式（71%），以及延伸到肺动脉瓣的彩色血流多普勒模式（51%）。与无症状犬相比，临床发现左心室增大，归一化彩色血流多普勒宽度（CFDw）（P=0.023）。透射峰E (E)、左室流出道速度、肺动脉彩色血流多普勒像素化填充率（CFD%）与左室尺寸相关。LCHF组CFDw大于LR分流术组（P=0.009），而LCHF组CFDw又大于PH组（P=0.004）。LCHF组的平均CFD%大于lr分流组（P=0.008）。研究局限性：回顾性数据收集限制了图像采集的标准化。由于缺乏观察者内部和观察者之间的可变性分析，适用性进一步受到限制。结论：PDA犬分流容量的多普勒测量包括左室和左室流出道速度、CFDw和CFD%。

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引用次数: 0

Histological evidence of myxomatous tissue in a Labrador puppy with pulmonic stenosis and tricuspid valve dysplasia 粘液瘤组织的组织学证据在拉布拉多犬与肺动脉狭窄和三尖瓣发育不良

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-07-29 DOI: 10.1016/j.jvc.2025.07.008

J. Schoebel , G. Wess , M. Tursi

A six-week-old Labrador retriever was presented for lethargy and anorexia, revealing a systolic heart murmur. Tricuspid valve dysplasia involving the whole tricuspid valve apparatus and the right ventricular wall was found, and an additional pulmonic stenosis was present. Histopathological examination of the tricuspid and pulmonary leaflets highlighted an unusual myxomatous mesenchymal component, interpreted as being of ontogenetic origin.

一只六周大的拉布拉多猎犬表现为嗜睡和厌食，显示收缩期心脏杂音。发现三尖瓣发育不良累及整个三尖瓣装置和右心室壁，并伴有肺动脉狭窄。三尖瓣和肺小叶的组织病理学检查突出了一种不寻常的黏液瘤间质成分，解释为个体起源。

引用次数: 0

Clinical utility of pharmacological defibrillation using cardioplegic solution during canine mitral valve repair 心脏截瘫液在犬二尖瓣修复术中除颤的临床应用

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-07-26 DOI: 10.1016/j.jvc.2025.07.002

K. Kurogochi , Y. Nii , A. Chen , M. Uechi

Introduction/Objectives

Reperfusion ventricular fibrillation (VF) commonly occurs during open-heart surgery in dogs and humans. Pharmacological defibrillation using cardioplegia is a potential option; however, the standard technique remains unclear in dogs. We examined the clinical utility of pharmacological defibrillation in canine mitral valve repair.

Animals, Materials, and Methods

We retrospectively investigated 402 client-owned dogs that underwent mitral valve repair between January and December 2021.

Results

Ventricular fibrillation after cross-clamp release occurred in 70 of 397 cases (17.6%). Pharmacological defibrillation was attempted in 69 patients by administering 40 mEq/L potassium crystalloid cardioplegia via an aortic root catheter. If defibrillation was not achieved or VF recurred, the administration was repeated identically. In all cases, VF resolved after pharmacological defibrillation alone, without electrical defibrillation. Defibrillation was achieved with a single dose in 45 cases (median, 3.90 mL/kg; interquartile range [IQR], 2.95–4.95]), while multiple doses (range: 2–5) were necessary for 24 cases (median initial dose, 3.05 mL/kg [IQR, 2.07–4.14]). Predictors of reperfusion VF included body temperature at cross-clamp release (risk ratio, 0.82 per 1.0 °C) and pre-operative left ventricular internal dimension at end-diastole normalized to body weight (risk ratio, 1.11 per 0.1 unit).

Study Limitations

The retrospective nature of the study led to variability in personnel, absence of a control group, and limited data availability.

Conclusions

Reperfusion VF occurred in 17.6% of the canine mitral valve repair cases. Pharmacological defibrillation is a feasible option in such cases. Approximately 4.0 mL/kg of cardioplegia was effective for a single dose, whereas lower doses required multiple administrations.

再灌注性心室颤动（VF）常见于狗和人的心内直视手术中。使用心脏截截术进行药物除颤是一种潜在的选择；然而，在狗身上的标准技术仍不清楚。我们检查了药物除颤在犬二尖瓣修复中的临床应用。动物、材料和方法我们回顾性调查了402只客户拥有的狗，这些狗在2021年1月至12月期间接受了二尖瓣修复。结果397例患者中有70例（17.6%）发生交叉夹松解后心室颤动。69例患者通过主动脉根部导管给予40 mEq/L钾晶体心脏骤停，尝试药理学除颤。如果没有实现除颤或室颤复发，则重复给药。在所有病例中，VF均在药物除颤而非电除颤后消失。45例患者单次给药（中位数，3.90 mL/kg；四分位数范围[IQR]， 2.95-4.95]）， 24例患者需要多次给药（范围：2-5）（中位数初始剂量，3.05 mL/kg [IQR, 2.07-4.14]）。再灌注VF的预测因子包括交叉钳释放时的体温（风险比，0.82 / 1.0°C）和术前舒张末期左心室内径与体重归一化（风险比，1.11 / 0.1单位）。研究局限性：本研究为回顾性研究，研究人员存在差异，缺乏对照组，数据可用性有限。结论17.6%的犬二尖瓣修复病例发生再灌注VF。在这种情况下，药物除颤是一种可行的选择。约4.0 mL/kg的心脏截止剂单次给药有效，而低剂量则需要多次给药。

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引用次数: 0

Clinical characteristics, echocardiographic findings, and computed tomography angiography in the diagnosis of sinus venosus atrial septal defect with partial anomalous pulmonary venous connection in 10 dogs 10只犬静脉窦房间隔缺损伴部分肺静脉连接异常的临床特点、超声心动图表现及计算机断层血管造影诊断

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-08-20 DOI: 10.1016/j.jvc.2025.08.004

A. Chen , K. Kurogochi , S. Ono , M. Uechi

Introduction/Objectives

Sinus venosus atrial septal defects (SVASDs) are frequently associated with partial anomalous pulmonary venous connections (PAPVCs) in humans, and computed tomography (CT) angiography provides high diagnostic accuracy. However, SVASD with PAPVC has been reported in only a few veterinary cases. This study evaluated CT for a definitive diagnosis and described the clinical and echocardiographic characteristics of dogs with SVASD and PAPVC.

Animals, Materials and Methods

Ten dogs diagnosed with SVASD using CT angiography were retrospectively reviewed. Transthoracic echocardiography was used for the initial assessment, and CT angiography confirmed the diagnosis. The clinical characteristics and echocardiographic findings were described.

Results

Transthoracic echocardiography revealed right atrial and ventricular dilation in each dog, with suspected SVASD in seven cases. In the remaining three dogs, echocardiography did not detect the SVASD. Computed tomography angiography identified a defect in the interatrial septum near the cranial vena cava in each case. Partial anomalous pulmonary venous connection was confirmed in all dogs, with drainage sites involving the right atrium, the junction with cranial vena cava, or the cranial vena cava. Nine dogs underwent surgical repair, and surgery was not recommended for one dog because of suspected severe pulmonary hypertension.

Study Limitations

The small number of cases limited statistical evaluation, and the retrospective design may have introduced bias in echocardiographic assessment.

Conclusions

Sinus venosus atrial septal defect in dogs is often accompanied by PAPVC, which was present in 100% of the cases in this group of dogs. Computed tomography proved to be a valuable diagnostic tool, enhancing the sensitivity of identifying SVASD and PAPVC in dogs.

简介/目的静脉窦房间隔缺损（SVASDs）通常与部分肺静脉连接异常（PAPVCs）相关，计算机断层扫描（CT）血管造影提供了较高的诊断准确性。然而，SVASD合并PAPVC仅在少数兽医病例中报道。本研究评估了CT对SVASD和PAPVC的明确诊断，并描述了SVASD和PAPVC犬的临床和超声心动图特征。动物、材料和方法回顾性分析10只经CT血管造影诊断为SVASD的犬。经胸超声心动图进行初步评估，CT血管造影证实诊断。描述了临床特点和超声心动图的表现。结果经胸超声心动图示右心房和心室扩张，7例疑似SVASD。其余3只犬，超声心动图未检测到SVASD。在每个病例中，计算机断层血管造影发现在颅腔静脉附近的房间隔有一个缺陷。所有犬均证实部分肺静脉连接异常，引流部位累及右心房、与颅腔静脉的连接处或颅腔静脉。9只狗接受了手术修复，1只狗因疑似严重肺动脉高压而不建议手术。研究局限性：病例数量少限制了统计评价，回顾性设计可能会在超声心动图评估中引入偏倚。结论犬静脉窦性房间隔缺损常伴有静脉窦性房间隔缺损，本组犬100%存在静脉窦性房间隔缺损。计算机断层扫描被证明是一种有价值的诊断工具，提高了识别SVASD和PAPVC的敏感性。

{"title":"Clinical characteristics, echocardiographic findings, and computed tomography angiography in the diagnosis of sinus venosus atrial septal defect with partial anomalous pulmonary venous connection in 10 dogs","authors":"A. Chen , K. Kurogochi , S. Ono , M. Uechi","doi":"10.1016/j.jvc.2025.08.004","DOIUrl":"10.1016/j.jvc.2025.08.004","url":null,"abstract":"<div><h3>Introduction/Objectives</h3><div>Sinus venosus atrial septal defects (SVASDs) are frequently associated with partial anomalous pulmonary venous connections (PAPVCs) in humans, and computed tomography (CT) angiography provides high diagnostic accuracy. However, SVASD with PAPVC has been reported in only a few veterinary cases. This study evaluated CT for a definitive diagnosis and described the clinical and echocardiographic characteristics of dogs with SVASD and PAPVC.</div></div><div><h3>Animals, Materials and Methods</h3><div>Ten dogs diagnosed with SVASD using CT angiography were retrospectively reviewed. Transthoracic echocardiography was used for the initial assessment, and CT angiography confirmed the diagnosis. The clinical characteristics and echocardiographic findings were described.</div></div><div><h3>Results</h3><div>Transthoracic echocardiography revealed right atrial and ventricular dilation in each dog, with suspected SVASD in seven cases. In the remaining three dogs, echocardiography did not detect the SVASD. Computed tomography angiography identified a defect in the interatrial septum near the cranial vena cava in each case. Partial anomalous pulmonary venous connection was confirmed in all dogs, with drainage sites involving the right atrium, the junction with cranial vena cava, or the cranial vena cava. Nine dogs underwent surgical repair, and surgery was not recommended for one dog because of suspected severe pulmonary hypertension.</div></div><div><h3>Study Limitations</h3><div>The small number of cases limited statistical evaluation, and the retrospective design may have introduced bias in echocardiographic assessment.</div></div><div><h3>Conclusions</h3><div>Sinus venosus atrial septal defect in dogs is often accompanied by PAPVC, which was present in 100% of the cases in this group of dogs. Computed tomography proved to be a valuable diagnostic tool, enhancing the sensitivity of identifying SVASD and PAPVC in dogs.</div></div>","PeriodicalId":48788,"journal":{"name":"Journal of Veterinary Cardiology","volume":"62 ","pages":"Pages 72-84"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145060202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epicardial pacemaker implantation in a young cat with sick sinus syndrome 心外膜起搏器植入一只患有病态窦性综合征的年轻猫。

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-09-12 DOI: 10.1016/j.jvc.2025.09.003

E.J.Y. Lo, C. Sanchez Villamil, J. Hannabuss, A.G.N. Morey

A one-year-old Abyssinian cat was referred for episodes of vacancy, exaggerated blinking, and intermittent collapse episodes. A 12-lead electrocardiogram (ECG) and ECG telemetry demonstrated sinus bradycardia, sinus pauses, and sinus arrest with a junctional escape rhythm. No infectious agents were identified as a cause of the bradyarrhythmia during systemic disease screening. Findings were consistent with idiopathic sick sinus syndrome. Theophylline therapy did not improve clinical signs or ECG findings. An epicardial pacemaker was placed, which alleviated clinical signs. Pacemaker interrogation after implantation showed minimal use of the pacemaker. This case report highlights the utility of ECG telemetry in describing electrocardiographic findings of sinus arrest, a junctional escape rhythm, and sinus bradycardia in a cat with clinical signs, consistent with sick sinus syndrome which resolved following epicardial pacemaker implantation.

一只一岁的阿比西尼亚猫被认为是空虚，夸张的眨眼和间歇性崩溃的发作。12导联心电图（ECG）和心电图遥测显示窦性心动过缓，窦性暂停，窦性骤停伴交界性逸出节律。在全身性疾病筛查期间，未发现感染性病原体是导致慢性心律失常的原因。结果与特发性病窦综合征一致。茶碱治疗没有改善临床症状或心电图表现。放置心外膜起搏器，减轻了临床症状。起搏器植入后的询问显示起搏器很少使用。本病例报告强调了心电图遥测在描述有临床症状的猫的窦性停搏、交界性逸出节律和窦性心动过缓的心电图表现方面的应用，这些症状与病态窦性综合征一致，在心外膜起搏器植入后消失。

引用次数: 0

Interobserver repeatability of interventricular septal wall measurements in cats 猫室间隔壁测量的观察者间可重复性

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-07-28 DOI: 10.1016/j.jvc.2025.07.007

A. Pires , W. Sears , S. Raheb , S. Fonfara

Introduction

Clinically, echocardiography is the gold standard test for diagnosing hypertrophic cardiomyopathy in cats. Low interobserver variability for echocardiographic measurements has generally been reported in the literature. We hypothesized that interobserver variability is high when measuring the interventricular septum (IVS) thickness in cats.

Materials and Methods

Echocardiographic right-sided parasternal left ventricular (LV) outflow tract views from four cats with different LV morphologies were selected. Five measurements of the IVS in each picture were performed by 29 veterinary cardiologists and cardiology residents from different institutions. Intraclass correlation coefficient (ICC) was applied for data analysis.

Results

Interobserver repeatability was poor for the base of the IVS (partial ICC: 0.4) and moderate for the rest of the IVS (partial ICC: 0.6). A range of 0.7 mm between the lower and upper limits of measurements was found for each picture and region of the IVS. Around 27% of variance in measurements was associated with training location (country), whereas around 73% of the variance was attributable to the observer.

Study Limitations

Study limitations included the use of still pictures and assessment of one echocardiographic parameter only.

Conclusions

As hypothesized, the interobserver repeatability of IVS measurements using the right-sided parasternal LV outflow tract view in cats was poor to moderate. This finding is relevant when comparing and interpreting measurements obtained by different observers. Additionally, the influence of training location may need to be considered when interpreting results of variability studies involving observers from the same facility.

在临床上，超声心动图是诊断猫肥厚性心肌病的金标准试验。超声心动图测量的低观察者间可变性已在文献中普遍报道。我们假设在测量猫室间隔（IVS）厚度时，观察者之间的变异性很高。材料与方法选择4只不同左室形态猫的右胸骨旁左室流出道超声心动图。来自不同机构的29名兽医心脏病专家和心脏病学住院医师对每张图片中的IVS进行了5次测量。采用类内相关系数（ICC）进行数据分析。结果观察者间重复性较差的是IVS的基础（部分ICC: 0.4），中等的是IVS的其余部分（部分ICC: 0.6）。对于IVS的每个图像和区域，在测量的下限和上限之间存在0.7 mm的范围。测量结果中约27%的方差与训练地点（国家）有关，而约73%的方差可归因于观察者。研究局限研究局限包括使用静止图像和仅评估一个超声心动图参数。结论如假设的那样，在猫中使用右侧胸骨旁左室流出道观察IVS测量的观察者之间的可重复性较差至中等。当比较和解释由不同观察者获得的测量结果时，这一发现是相关的。此外，在解释涉及同一设施观察员的变异性研究结果时，可能需要考虑培训地点的影响。

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引用次数: 0

Transient dilated cardiomyopathy phenotype and positive Bartonella serology in a cat 猫一过性扩张型心肌病表型和巴尔通体血清学阳性。

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology

Pub Date : 2025-12-01 Epub Date: 2025-09-11 DOI: 10.1016/j.jvc.2025.09.002

B. Ditzler , B. Lozano , C. Jones , M. Henderson , A.B. Saunders

A one-and-a-half-year-old spayed female domestic shorthaired cat, originally obtained as a stray, presented with a two-day history of lethargy, anorexia, and progressive dyspnea. Point-of-care ultrasound showed marked bilateral pleural effusion and a small volume of ascites. Thoracocentesis resulted in the removal of 220 mL of protein poor transudate. Subsequently, a gallop was auscultated and an echocardiogram was performed. Significant findings on echocardiography were a dilated cardiomyopathy phenotype characterized by biventricular eccentric hypertrophy with normal left ventricular diastolic wall thickness and reduced biventricular systolic function with biatrial enlargement. The cat was fed a standard diet and had adequate plasma and whole blood taurine concentration. Infectious disease testing detected Bartonella spp. immunoglobulin G antibodies (1:512) including Bartonella vinsonii of which the cat is not a natural reservoir host. The cat was treated for dilated cardiomyopathy and congestive heart failure with pimobendan, furosemide, and clopidogrel as well as with pradofloxacin and doxycycline for suspected bartonellosis. At 2.5-, 5-, and 9-month rechecks, echocardiogram findings were markedly improved with a reduction in atrial and ventricular chamber enlargement to normal and normal ventricular systolic function and without any further evidence of congestive heart failure. Repeat Bartonella spp. titers were unchanged at 2.5 months. This case describes reverse remodeling of a dilated cardiomyopathy phenotype and resolution of congestive heart failure with discontinuation of cardiac medications in a young cat with suspected Bartonella myocarditis.

一只一岁半的雌性家养短毛猫，最初是作为流浪猫获得的，出现了两天的嗜睡，厌食和进行性呼吸困难的历史。即时超声显示双侧明显胸腔积液和少量腹水。经胸穿刺术取出220毫升蛋白质漏出物。随后，听诊疾驰并进行超声心动图检查。超声心动图的重要发现是扩张型心肌病，其特征是双室偏心肥厚，左室舒张壁厚度正常，双室收缩功能减弱，双房扩大。猫被喂食标准饮食，血浆和全血牛磺酸浓度充足。传染病检测检测到巴尔通体免疫球蛋白G抗体（1:12 12），包括猫不是其天然宿主的文氏巴尔通体。这只猫因扩张性心肌病和充血性心力衰竭接受了匹莫苯丹、呋塞米和氯吡格雷的治疗，并因疑似巴尔通体病接受了普拉多沙星和多西环素的治疗。在2.5个月、5个月和9个月复查时，超声心动图结果明显改善，心房和心室增大至正常和心室收缩功能正常，无进一步充血性心力衰竭的证据。重复巴尔通体滴度在2.5个月时保持不变。本病例描述了扩张型心肌病表型的反向重塑和充血性心力衰竭的解决与停止心脏药物在一个年轻的猫怀疑巴尔通体心肌炎。

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引用次数: 0