Pub Date : 2025-12-28DOI: 10.1016/j.jshs.2025.101119
Chao Yang
{"title":"Commentary on “Interplay between physical activity volume and intensity with modeled life expectancy in women and men: A prospective cohort analysis”","authors":"Chao Yang","doi":"10.1016/j.jshs.2025.101119","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101119","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"20 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1016/j.jshs.2025.101114
Robyn M. Murphy, Mark A. Febbraio
{"title":"The biochemical and metabolic adaptations underpinning the health benefits of exercise","authors":"Robyn M. Murphy, Mark A. Febbraio","doi":"10.1016/j.jshs.2025.101114","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101114","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"25 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-24DOI: 10.1016/j.jshs.2025.101116
Miguel Adriano Sanchez-Lastra, Borja del Pozo Cruz, Jakob Tarp, Knut Eirik Dalene, Tormod S. Nilsen, Ding Ding, Ulf Ekelund
{"title":"Dose‒response associations of self-reported and device-measured physical activity with major adverse cardiovascular events in people with prevalent diseases","authors":"Miguel Adriano Sanchez-Lastra, Borja del Pozo Cruz, Jakob Tarp, Knut Eirik Dalene, Tormod S. Nilsen, Ding Ding, Ulf Ekelund","doi":"10.1016/j.jshs.2025.101116","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101116","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"22 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.jshs.2025.101112
Karim Abu-Omar, Tobias Völk, Antonina Tcymbal, Julian Resch, Dogukan Özer, Peter Gelius, Sven Messing, Heiko Ziemainz
{"title":"Mitigating climate change in sports leagues: A scenario-based analysis of travel distances in women’s and men’s amateur soccer in Germany","authors":"Karim Abu-Omar, Tobias Völk, Antonina Tcymbal, Julian Resch, Dogukan Özer, Peter Gelius, Sven Messing, Heiko Ziemainz","doi":"10.1016/j.jshs.2025.101112","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101112","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"43 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145784420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1016/j.jshs.2025.101113
Lian Wang, Liwei Mao, Danlin Zhu, Ke Li, Haoyang Gao, Muge Zhou, Jiabin Wu, Dan Yang, Ze Wang, Wenhong Wang, Yifan Guo, Yingying Xu, Peijie Chen, Weihua Xiao
{"title":"Exercise-induced β-hydroxybutyrate contributes to cognitive improvement in aging mice","authors":"Lian Wang, Liwei Mao, Danlin Zhu, Ke Li, Haoyang Gao, Muge Zhou, Jiabin Wu, Dan Yang, Ze Wang, Wenhong Wang, Yifan Guo, Yingying Xu, Peijie Chen, Weihua Xiao","doi":"10.1016/j.jshs.2025.101113","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101113","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"48 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145784419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-16DOI: 10.1016/j.jshs.2025.101110
John W A Osborne,Hylton B Menz,Karl B Landorf,Glen A Whittaker,Matthew Cotchett,Luke A Kelly
BACKGROUNDIntrinsic and extrinsic foot muscles contribute to foot and lower limb function. This knowledge provides opportunities to target these muscles in exercise and rehabilitation. However, a barrier is the limited understanding of how prescribed exercises affect muscle activation and force output. This study examined muscle activation and torque production about the metatarsophalangeal joints of intrinsic and extrinsic foot muscles during common foot strengthening exercises. The secondary aim was to determine whether the addition of a postural change (leaning forward) or addition of mass can further increase muscle activation and torque.METHODSFifteen healthy participants (9 males, 6 females; age = 36.5 ± 8 years, mean ± SD) participated. Muscle activation was measured using fine-wire electromyography (EMG) electrodes for 2 intrinsic and 2 extrinsic muscles, and surface EMG electrodes for 4 superficial muscles. Metatarsophalangeal joint torque was measured using a custom toe dynamometer. Participants attended one 90-min session and performed 16 exercises. Five included the addition of leaning forward and 3 the addition of mass (20% of participant's mass) to compare their effects on muscle activity and torque.RESULTSMuscle activation and metatarsophalangeal joint torque varied considerably across exercises. Both the addition of leaning forward and the addition of mass increased muscle activation and metatarsophalangeal joint torque, with the addition of leaning forward producing a 35% median increase in torque about the metatarsophalangeal joints.CONCLUSIONMany common exercises, despite high muscle activation, produce relatively low metatarsophalangeal joint torque, raising questions about their clinical value. Adding a forward lean significantly increases toe flexor muscle activity and torque, reaching levels greater than added mass and comparable to walking.
{"title":"The influence of body posture and added mass on intrinsic and extrinsic foot muscle activation and force output during common foot strengthening exercises.","authors":"John W A Osborne,Hylton B Menz,Karl B Landorf,Glen A Whittaker,Matthew Cotchett,Luke A Kelly","doi":"10.1016/j.jshs.2025.101110","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101110","url":null,"abstract":"BACKGROUNDIntrinsic and extrinsic foot muscles contribute to foot and lower limb function. This knowledge provides opportunities to target these muscles in exercise and rehabilitation. However, a barrier is the limited understanding of how prescribed exercises affect muscle activation and force output. This study examined muscle activation and torque production about the metatarsophalangeal joints of intrinsic and extrinsic foot muscles during common foot strengthening exercises. The secondary aim was to determine whether the addition of a postural change (leaning forward) or addition of mass can further increase muscle activation and torque.METHODSFifteen healthy participants (9 males, 6 females; age = 36.5 ± 8 years, mean ± SD) participated. Muscle activation was measured using fine-wire electromyography (EMG) electrodes for 2 intrinsic and 2 extrinsic muscles, and surface EMG electrodes for 4 superficial muscles. Metatarsophalangeal joint torque was measured using a custom toe dynamometer. Participants attended one 90-min session and performed 16 exercises. Five included the addition of leaning forward and 3 the addition of mass (20% of participant's mass) to compare their effects on muscle activity and torque.RESULTSMuscle activation and metatarsophalangeal joint torque varied considerably across exercises. Both the addition of leaning forward and the addition of mass increased muscle activation and metatarsophalangeal joint torque, with the addition of leaning forward producing a 35% median increase in torque about the metatarsophalangeal joints.CONCLUSIONMany common exercises, despite high muscle activation, produce relatively low metatarsophalangeal joint torque, raising questions about their clinical value. Adding a forward lean significantly increases toe flexor muscle activity and torque, reaching levels greater than added mass and comparable to walking.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"6 1","pages":"101110"},"PeriodicalIF":11.7,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145777293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-16DOI: 10.1016/j.jshs.2025.101111
Noni T Frankenberg,Victoria L Wyckelsma,Dion Ellul,Aaron C Petersen,Itamar Levinger,Michael J McKenna,Robyn M Murphy
BACKGROUNDHeat shock proteins (HSPs) are key molecular chaperones that help maintain protein homeostasis by stabilising or removing damaged proteins during cellular stress. Aging weakens these stress-response systems, disrupting proteostasis and increasing vulnerability to sarcopenia. High-intensity training (HIT) can counteract these declines by activating protective pathways such as the HSP response. HSPs are highly responsive to stress, examining their regulation during aging is important, as altered HSP activity is linked to the progressive loss of muscle mass.METHODSThis study investigated the abundance and phosphorylation of HSPs in skeletal muscle from healthy, active young and older adults (n = 7 per group), assessed at baseline and again in the older group following 12 weeks of HIT. Using calibrated Western blotting on both whole-muscle homogenates and pooled single muscle fibres, we quantified HSP content and phosphorylation to determine how aging and exercise influence stress-responsive protein regulation at both the tissue and cellular levels.RESULTSIn whole muscle homogenates, HSPs (HSP72, HSP27, and αB-crystallin) did not differ between young and older adults, while higher phosphorylation of small HSPs (sHSPs): phospho-HSP27 at Serine15 (pHSP27 Ser15) and phospho-αB-crystallin at Serine59 (pαB-crystallin Ser59) (∼1.8-fold and ∼2.9-fold, respectively) were found in muscle from older adults, indicating higher cellular stress associated with aging. A 12-week HIT intervention in older adults reduced homogenate pHSP27 Ser15 and pαB-crystallin Ser59 abundances to similar levels found in young adults. Total HSPs typically displayed a distinct fiber-type profile in both age groups, with more in type I compared to type II fibers, distinguished by the presence of myosin heavy chain I (MHCI) or MHCII. Phosphorylation at pHSP27 Ser15 and pαB-crystallin Ser59 was not different between type I and type II fibers. The HIT in older adults decreased total and phosphorylated sHSPs in both type I and type II fibers but increased HSP72 in type I fibers.CONCLUSIONHIT has the potential to mitigate age-related cellular stress and modulate protein expression patterns in aging skeletal muscle and, perhaps, has the potential to delay age-related muscle decline, thereby improving muscle health in older adults.
{"title":"Exercise attenuates stress-related signaling as sensed by higher phosphorylation of small heat shock proteins in skeletal muscle from older individuals.","authors":"Noni T Frankenberg,Victoria L Wyckelsma,Dion Ellul,Aaron C Petersen,Itamar Levinger,Michael J McKenna,Robyn M Murphy","doi":"10.1016/j.jshs.2025.101111","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101111","url":null,"abstract":"BACKGROUNDHeat shock proteins (HSPs) are key molecular chaperones that help maintain protein homeostasis by stabilising or removing damaged proteins during cellular stress. Aging weakens these stress-response systems, disrupting proteostasis and increasing vulnerability to sarcopenia. High-intensity training (HIT) can counteract these declines by activating protective pathways such as the HSP response. HSPs are highly responsive to stress, examining their regulation during aging is important, as altered HSP activity is linked to the progressive loss of muscle mass.METHODSThis study investigated the abundance and phosphorylation of HSPs in skeletal muscle from healthy, active young and older adults (n = 7 per group), assessed at baseline and again in the older group following 12 weeks of HIT. Using calibrated Western blotting on both whole-muscle homogenates and pooled single muscle fibres, we quantified HSP content and phosphorylation to determine how aging and exercise influence stress-responsive protein regulation at both the tissue and cellular levels.RESULTSIn whole muscle homogenates, HSPs (HSP72, HSP27, and αB-crystallin) did not differ between young and older adults, while higher phosphorylation of small HSPs (sHSPs): phospho-HSP27 at Serine15 (pHSP27 Ser15) and phospho-αB-crystallin at Serine59 (pαB-crystallin Ser59) (∼1.8-fold and ∼2.9-fold, respectively) were found in muscle from older adults, indicating higher cellular stress associated with aging. A 12-week HIT intervention in older adults reduced homogenate pHSP27 Ser15 and pαB-crystallin Ser59 abundances to similar levels found in young adults. Total HSPs typically displayed a distinct fiber-type profile in both age groups, with more in type I compared to type II fibers, distinguished by the presence of myosin heavy chain I (MHCI) or MHCII. Phosphorylation at pHSP27 Ser15 and pαB-crystallin Ser59 was not different between type I and type II fibers. The HIT in older adults decreased total and phosphorylated sHSPs in both type I and type II fibers but increased HSP72 in type I fibers.CONCLUSIONHIT has the potential to mitigate age-related cellular stress and modulate protein expression patterns in aging skeletal muscle and, perhaps, has the potential to delay age-related muscle decline, thereby improving muscle health in older adults.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"162 1","pages":"101111"},"PeriodicalIF":11.7,"publicationDate":"2025-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145777292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-04DOI: 10.1016/j.jshs.2025.101108
Yan Qiu,Benjamin Fernández-García,H Immo Lehmann,Guoping Li,Guido Kroemer,Carlos López-Otín,Junjie Xiao
The number and proportion of individuals aged 60 years and older are steadily increasing. However, increased life expectancy is accompanied by a decline in functional capacity and a heightened risk of age-related diseases, ultimately leading to reduced quality of life. Interventions that support physiological function in later life and hence extend healthspan are therefore of considerable importance. Among these, regular physical exercise is strongly associated with numerous health benefits and is recognized as a key strategy for promoting healthy aging and extending healthspan. In this review, we highlight the impact of an active lifestyle, particularly regular physical activity, on the major hallmarks of aging. These include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, impaired macroautophagy, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, changes in the extracellular matrix, stem cell exhaustion, altered intercellular communication, chronic inflammation, dysbiosis, and psychosocial isolation. A deeper understanding of the mechanisms by which exercise confers these benefits will aid in enhancing both physical and mental health in the elderly and in mitigating the onset of aging-associated diseases.
{"title":"Exercise attenuates the hallmarks of aging: Novel perspectives.","authors":"Yan Qiu,Benjamin Fernández-García,H Immo Lehmann,Guoping Li,Guido Kroemer,Carlos López-Otín,Junjie Xiao","doi":"10.1016/j.jshs.2025.101108","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101108","url":null,"abstract":"The number and proportion of individuals aged 60 years and older are steadily increasing. However, increased life expectancy is accompanied by a decline in functional capacity and a heightened risk of age-related diseases, ultimately leading to reduced quality of life. Interventions that support physiological function in later life and hence extend healthspan are therefore of considerable importance. Among these, regular physical exercise is strongly associated with numerous health benefits and is recognized as a key strategy for promoting healthy aging and extending healthspan. In this review, we highlight the impact of an active lifestyle, particularly regular physical activity, on the major hallmarks of aging. These include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, impaired macroautophagy, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, changes in the extracellular matrix, stem cell exhaustion, altered intercellular communication, chronic inflammation, dysbiosis, and psychosocial isolation. A deeper understanding of the mechanisms by which exercise confers these benefits will aid in enhancing both physical and mental health in the elderly and in mitigating the onset of aging-associated diseases.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"1 1","pages":"101108"},"PeriodicalIF":11.7,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-04DOI: 10.1016/j.jshs.2025.101107
Chris Bleakley
{"title":"Does ice affect healing after muscle injury? Ask me again next century.","authors":"Chris Bleakley","doi":"10.1016/j.jshs.2025.101107","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101107","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"36 1","pages":"101107"},"PeriodicalIF":11.7,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-04DOI: 10.1016/j.jshs.2025.101109
José Francisco López-Gil,Mark S Tremblay,Maira Bes-Rastrollo,Laura Moreno-Galarraga,Stefanos N Kales,Miguel Ángel Martínez-González,Alejandro Fernandez-Montero
OBJECTIVEThe purpose of this study is to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.METHODSWe analyzed data from 14,288 participants of the Seguimiento Universidad de Navarra (SUN) Project, followed for a mean of 12.8 years (mean baseline age = 38.3 years; 60.1% women). Data were collected at baseline and through biennial follow-up questionnaires (up to 10 waves, depending on year of entry). The participants self-reported 24-h movement behaviors at baseline and were categorized based on the number of guidelines met (0-3). Behaviors were assessed at baseline only; changes in adherence during follow-up were not accounted for. Cox proportional hazards models were used to estimate hazard ratios (HRs) for all-cause and cause-specific mortality, adjusting for sociodemographic, lifestyle, and clinical covariates.RESULTSMeeting a greater number of 24-Hour Movement Guidelines at baseline was associated with a progressively lower risk of all-cause mortality. Compared with those meeting none, the multivariable-adjusted HRs were 0.52 (95% confidence interval (95%CI): 0.33-0.82) for meeting 1 guideline, 0.47 (95%CI: 0.30-0.73) for meeting 2 guidelines, and 0.44 (95%CI: 0.28-0.71) for meeting all 3 guidelines. Only adherence to the physical activity guidelines was independently associated with a significantly lower mortality risk (HR = 0.70; 95%CI: 0.55-0.89). A reduced risk was also observed for cancer and other-cause mortality among those meeting 2 or more guidelines.CONCLUSIONAdherence to the 24-Hour Movement Guidelines at baseline, particularly physical activity, was associated with a lower risk of mortality. Promoting an integrated approach to movement behaviors may be an effective strategy for improving population health and longevity.
{"title":"Adherence to the 24-Hour Movement Guidelines is related to a lower risk of all-cause mortality: A prospective cohort study of 14,288 participants from the SUN Project.","authors":"José Francisco López-Gil,Mark S Tremblay,Maira Bes-Rastrollo,Laura Moreno-Galarraga,Stefanos N Kales,Miguel Ángel Martínez-González,Alejandro Fernandez-Montero","doi":"10.1016/j.jshs.2025.101109","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101109","url":null,"abstract":"OBJECTIVEThe purpose of this study is to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.METHODSWe analyzed data from 14,288 participants of the Seguimiento Universidad de Navarra (SUN) Project, followed for a mean of 12.8 years (mean baseline age = 38.3 years; 60.1% women). Data were collected at baseline and through biennial follow-up questionnaires (up to 10 waves, depending on year of entry). The participants self-reported 24-h movement behaviors at baseline and were categorized based on the number of guidelines met (0-3). Behaviors were assessed at baseline only; changes in adherence during follow-up were not accounted for. Cox proportional hazards models were used to estimate hazard ratios (HRs) for all-cause and cause-specific mortality, adjusting for sociodemographic, lifestyle, and clinical covariates.RESULTSMeeting a greater number of 24-Hour Movement Guidelines at baseline was associated with a progressively lower risk of all-cause mortality. Compared with those meeting none, the multivariable-adjusted HRs were 0.52 (95% confidence interval (95%CI): 0.33-0.82) for meeting 1 guideline, 0.47 (95%CI: 0.30-0.73) for meeting 2 guidelines, and 0.44 (95%CI: 0.28-0.71) for meeting all 3 guidelines. Only adherence to the physical activity guidelines was independently associated with a significantly lower mortality risk (HR = 0.70; 95%CI: 0.55-0.89). A reduced risk was also observed for cancer and other-cause mortality among those meeting 2 or more guidelines.CONCLUSIONAdherence to the 24-Hour Movement Guidelines at baseline, particularly physical activity, was associated with a lower risk of mortality. Promoting an integrated approach to movement behaviors may be an effective strategy for improving population health and longevity.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"1 1","pages":"101109"},"PeriodicalIF":11.7,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}