Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Estado del arte y perspectivas futuras de nuevos radionúclidos en Medicina Nuclear. Parte I","authors":"J.J. Rosales ,&nbsp;M.L. Domínguez ,&nbsp;L. Sancho ,&nbsp;E. Prieto ,&nbsp;M. de Arcocha ,&nbsp;I. Torres ,&nbsp;A. Roteta ,&nbsp;R. Ramos ,&nbsp;G. Quincoces ,&nbsp;en nombre del Grupo de Oncología de la SEMNIM","doi":"10.1016/j.remn.2024.500082","DOIUrl":"10.1016/j.remn.2024.500082","url":null,"abstract":"<div><div>This continuing education analyzes recent advances in Nuclear Medicine focused on the development of new radiopharmaceuticals that improve both the diagnosis and treatment of complex diseases. The focus is on teragnosis, which combines diagnosis and treatment by means of pairs of radiopharmaceuticals directed to the same molecular target, which allows the personalization of treatments.</div><div>This first part specifically reviews the teragnostic pairs copper-64/copper-67, lead-212/lead-203 and scandium-44/scandium-47, highlighting their physical characteristics, methods of production and potential clinical applications.</div><div>Despite the challenges in their production, their versatility and effectiveness are driving their clinical application in oncology and other diseases. The text also addresses the development of new radiopharmaceuticals and their impact on precision medicine, pointing out future directions and opportunities for research in this field.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500082"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de la fiabilidad y legibilidad de las respuestas de los chatbots como recurso de información al paciente para las exploraciones PET-TC más comunes","authors":"N. Aydinbelge-Dizdar ,&nbsp;K. Dizdar","doi":"10.1016/j.remn.2024.500065","DOIUrl":"10.1016/j.remn.2024.500065","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to evaluate the reliability and readability of responses generated by two popular AI-chatbots, ‘ChatGPT-4.0’ and ‘Google Gemini’, to potential patient questions about PET/CT scans.</div></div><div><h3>Materials and methods</h3><div>Thirty potential questions for each of [¹⁸F]FDG and [⁶⁸Ga]Ga-DOTA-SSTR PET/CT, and twenty-nine potential questions for [⁶⁸Ga]Ga-PSMA PET/CT were asked separately to ChatGPT-4 and Gemini in May 2024. The responses were evaluated for reliability and readability using the modified DISCERN (mDISCERN) scale, Flesch Reading Ease (FRE), Gunning Fog Index (GFI), and Flesch-Kincaid Reading Grade Level (FKRGL). The inter-rater reliability of mDISCERN scores provided by three raters (ChatGPT-4, Gemini, and a nuclear medicine physician) for the responses was assessed.</div></div><div><h3>Results</h3><div>The median [min-max] mDISCERN scores reviewed by the physician for responses about FDG, PSMA and DOTA PET/CT scans were 3.5 [2-4], 3 [3-4], 3 [3-4] for ChatGPT-4 and 4 [2-5], 4 [2-5], 3.5 [3-5] for Gemini, respectively. The mDISCERN scores assessed using ChatGPT-4 for answers about FDG, PSMA, and DOTA-SSTR PET/CT scans were 3.5 [3-5], 3 [3-4], 3 [2-3] for ChatGPT-4, and 4 [3-5], 4 [3-5], 4 [3-5] for Gemini, respectively. The mDISCERN scores evaluated using Gemini for responses FDG, PSMA, and DOTA-SSTR PET/CTs were 3 [2-4], 2 [2-4], 3 [2-4] for ChatGPT-4, and 3 [2-5], 3 [1-5], 3 [2-5] for Gemini, respectively. The inter-rater reliability correlation coefficient of mDISCERN scores for ChatGPT-4 responses about FDG, PSMA, and DOTA-SSTR PET/CT scans were 0.629 (95% CI= 0,32-0,812), 0.707 (95% CI<!--> <!-->=<!--> <!-->0.458-0.853) and 0.738 (95% CI<!--> <!-->=<!--> <!-->0.519-0.866), respectively (p&lt;<!--> <!-->0.001). The correlation coefficient of mDISCERN scores for Gemini responses about FDG, PSMA, and DOTA-SSTR PET/CT scans were 0.824 (95% CI<!--> <!-->=<!--> <!-->0.677-0.910), 0.881 (95% CI<!--> <!-->=<!--> <!-->0.78-0.94) and 0.847 (95% CI<!--> <!-->=<!--> <!-->0.719-0.922), respectively (p&lt;<!--> <!-->0.001). The mDISCERN scores assessed by ChatGPT-4, Gemini, and the physician showed that the chatbots’ responses about all PET/CT scans had moderate to good statistical agreement according to the inter-rater reliability correlation coefficient (p&lt;<!--> <!-->0,001). There was a statistically significant difference in all readability scores (FKRGL, GFI, and FRE) of ChatGPT-4 and Gemini responses about PET/CT scans (p&lt;<!--> <!-->0,001). Gemini responses were shorter and had better readability scores than ChatGPT-4 responses.</div></div><div><h3>Conclusion</h3><div>There was an acceptable level of agreement between raters for the mDISCERN score, indicating agreement with the overall reliability of the responses. However, the information provided by AI-chatbots cannot be easily read by the public.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500065"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metástasis ganglionares mediastínicas de cáncer de próstata: mayor precisión diagnóstica de la PET/TC con 18F-DCFPyL frente a la 18F-colina","authors":"R.M. Angulo Amorese,&nbsp;F.J. Pena Pardo,&nbsp;J.C. Rodríguez Gómez,&nbsp;N. Disotuar Ruiz,&nbsp;M.P. Talavera Rubio,&nbsp;V.M. Poblete García","doi":"10.1016/j.remn.2024.500063","DOIUrl":"10.1016/j.remn.2024.500063","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500063"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asociación de los hallazgos de la PET-TC y la VATS con la histología pleural en el estudio del derrame pleural","authors":"M. Simó ,&nbsp;O. Persiva ,&nbsp;L. Sánchez ,&nbsp;J.B. Montoro ,&nbsp;I. Sansano ,&nbsp;A. Vázquez ,&nbsp;F. Ascanio ,&nbsp;C. Alemán","doi":"10.1016/j.remn.2024.500059","DOIUrl":"10.1016/j.remn.2024.500059","url":null,"abstract":"<div><h3>Introduction</h3><div>Histological analysis of the pleura obtained by video-assisted thoracoscopic surgery (VATS) is the best diagnostic technique in the study of neoplastic pleural effusions. This study evaluates the relationship between positron emission tomography (PET)/computed tomography (CT) and VATS findings, the result of the first pleural biopsy, and the final diagnosis of malignancy or non-malignancy.</div></div><div><h3>Methods</h3><div>Prospective study of consecutive patients with pleural effusions undergoing PET/CT and VATS from October 2013 to December 2023. The following variables were recorded: PET/CT score (nodular pleural thickening, pleural nodules with standardized uptake value (SUV) &gt;<!--> <!-->7.5, lung mass or extra pleural malignancy, mammary lymph node with SUV &gt;<!--> <!-->4.5 and cardiomegaly); VATS data (drained volume, visceral and parietal pleural thickening, nodules or masses, septa, plaques, fluid appearance, trapped lung, and suspected diagnosis of the procedure), as well as the histological study of the first pleural biopsy (benign or malignant) and the final diagnosis of benign or malignant pleural effusion. A logistic regression study of the variables was performed.</div></div><div><h3>Results</h3><div>95.8% of the patients with PET/CT and pleuroscopy not suggestive of malignancy had non-malignant histological findings, while 93.2% of the patients with PET/CT and pleuroscopy suggestive of malignancy had malignant histological findings. PET/CT, pleuroscopy, and the result of the first pleural biopsy showed a significant association with the final diagnosis of pleural effusion.</div></div><div><h3>Conclusions</h3><div>There is a strong association between PET/CT findings, VATS and pleural histology.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500059"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET-TC [18F]F-Colina y PTH intraoperatoria en el tratamiento quirúrgico del hiperparatiroidismo primario sin localización preoperatoria","authors":"F.G. García-García ,&nbsp;N. Cassinello Fernández ,&nbsp;J. Rodríguez Romera ,&nbsp;R. Martí Fernández ,&nbsp;M. Lapeña Rodríguez ,&nbsp;R. Alfonso Ballester ,&nbsp;R. Díaz Expósito ,&nbsp;J. Ortega Serrano","doi":"10.1016/j.remn.2024.500066","DOIUrl":"10.1016/j.remn.2024.500066","url":null,"abstract":"<div><h3>Background and objectives</h3><div>To assess the feasibility of performing selective parathyroidectomy without intraoperative parathyroid hormone (PTHio) determination when first-line preoperative localization tests (ultrasonography and [^99mTc]Tc-MIBI) are negative and/or discordant, and second-line [¹⁸F]F-Colina PET-CT, is positive.</div></div><div><h3>Materials and methods</h3><div>Retrospective cohort study, including patients with negative or discordant ultrasound and MIBI scans and positive [¹⁸F]F-Colina PET-CT, who underwent selective parathyroidectomy between 2019 and 2022. Groups were compared based on PTHio determination. Study variables were: gender, mean age, biochemical cure assessed by PTH value (pg/mL) and corrected calcium by albumin (mg/dL) at 6 months post-surgery follow-up, and histopathological analysis.</div></div><div><h3>Results</h3><div>The final sample included 42 patients. At 6 months post-surgery, in the PTHio group (20 patients), PTH values were 64.50 pg/mL and calcium 9.30 pg/mL, with 19 adenomas and 1 hyperplasia found. In the non-PTHio group (22 patients), PTH values were 61 pg/mL and calcium 9.37 pg/mL, with 22 adenomas found. No statistically significant differences were found between both groups.</div></div><div><h3>Conclusions</h3><div>Based on the results obtained in our patient cohort, selective parathyroidectomy could be considered with negative or discordant first-line tests and positive [¹⁸F]F-Colina PET-CT, without intraoperative PTH determination.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500066"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG PET/TC en la estadificación, evaluación terapéutica y seguimiento de un sarcoma prostático","authors":"I. Martínez-Rodríguez,&nbsp;F. Gómez-de la Fuente,&nbsp;A. Sánchez-Salmón,&nbsp;M. Pombo-López,&nbsp;A. Bota-Bota,&nbsp;R. Quirce","doi":"10.1016/j.remn.2024.500039","DOIUrl":"10.1016/j.remn.2024.500039","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500039"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remisión metabólica completa de neoplasia blástica generalizada de células dendríticas plasmocitoides tras tratamiento","authors":"N. Filizoglu ,&nbsp;S. Ozguven","doi":"10.1016/j.remn.2024.500040","DOIUrl":"10.1016/j.remn.2024.500040","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500040"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uso de propranolol en 18F-FDG-PET/TC para el diagnóstico diferencial de grasa parda en una paciente con antecedente de adenocarcinoma de cérvix uterino","authors":"A. Garcia Garcia ,&nbsp;A.P. Caresia Aróztegui ,&nbsp;S. Martínez Román","doi":"10.1016/j.remn.2024.500068","DOIUrl":"10.1016/j.remn.2024.500068","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500068"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efecto antitumoral de la vertebroplastia en la metástasis vertebral basado en el análisis cuantitativo de la PET/TC con 18F-FDG","authors":"L. Bian ,&nbsp;C. Yang ,&nbsp;S.-w. Yin ,&nbsp;C.-f. Ni","doi":"10.1016/j.remn.2024.500028","DOIUrl":"10.1016/j.remn.2024.500028","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500028"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gammagrafía peritoneal y SPECT/CT en el diagnóstico de fugas en pacientes en diálisis peritoneal","authors":"D. Tercero Garrido ,&nbsp;M.V. Guiote Moreno ,&nbsp;C. Rodelo-Haad ,&nbsp;P.I. Contreras Puertas ,&nbsp;S. Soriano Cabrera ,&nbsp;M.D. Albalá González","doi":"10.1016/j.remn.2024.500067","DOIUrl":"10.1016/j.remn.2024.500067","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the usefulness of peritoneal cavity scintigraphy and the contribution of SPECT/CT in patients on peritoneal dialysis with suspected leak.</div></div><div><h3>Methodology</h3><div>An observational case series study is carried out. It consists of a longitudinal, retrospective and descriptive study. 11 patients on peritoneal dialysis were studied and it was realiced a peritoneal cavity scintigraphy test and SPECT/CT to evaluate a peritoneal leak.</div></div><div><h3>Results</h3><div>In 54,5% of the patients, a positive study of peritoneal leak was obtained. The most frequent localitations were in the abdominal wall at the catheter entry level and the inguinal hernia. In the cases with sintomatology like pain and celullitis of the subcutaneous tract of the cateter the frequent of leak was 100%. There was a change in therapeutic management in patients with a positive study. There was not relevant changes in initial dialysis regimen in patients with a negative study. In this cases, except for one patient who required hemodialysis, all patients experienced clinical improvement.</div></div><div><h3>Conclusions</h3><div>Peritoneal scintigraphy and SPECT/CT study are non-invasive techniques that allow an adequate diagnosis and subsequent management of peritoneal leak.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 1","pages":"Article 500067"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}