Hazem E M Hassanien, Awad M M Mahmoud, Elsayed Mohammed ABDEL-ROUF, N. Eweedah
Dietary cation-anion difference (DCAD) initiates a compensatory metabolic acidosis, which improves calcium (Ca) absorption and mobilization before calving and minimizes clinical and subclinical hypocalcaemia after calving. The goal of this study was to evaluate how mineral concentrations, blood metabolites, parathyroid hormone (PTH), and productive performance were affected by prepartum dietary cation-anion difference (DCAD mEq [(Na + K – Cl + S)]/kg of dry matter (DM)) in postpartum dairy cows. Forty-eight multiparous Holstein cows ranging from 2 to 5 lactations with an average body weight of 685 ± 10 kg (mean ± SD) were allocated in a randomized block design with three prepartum diets differing in DCAD (0, –100, and –180 mEq/ kg DM). All cows were fed the same postpartum diet and kept on trial for 66 days. Cows fed –180 and –100 mEq DCAD had greater prepartum non-esterified fatty acid (NEFA) concentrations than cows fed 0 mEq DCAD. Cows fed –180 mEq DCAD had greater serum Ca concentrations than cows fed –100 and 0 mEq DCAD. PTH concentrations were greater in cows fed 0 mEq DCAD than in cows fed –100 or –180 mEq DCAD. Cows fed 0 mEq DCAD had higher milk protein and solid-not-fat (SNF) levels than cows fed –100 or –180 mEq DCAD. Treatment and interaction had no effect on milk yield, 3.5% fat-corrected milk (FCM), energy-corrected milk (ECM), milk fat, total solids (TS), lactose, milk urea nitrogen (MUN), magnesium (Mg), sodium (Na), chloride (Cl), potassium (K), beta hydroxybutyric acid (BHBA), and liver or kidney functions. We concluded that adding anionic salts to dairy cows’ diets (–100 and –180 mEq DCAD) improved postpartum Ca availability and reduced clinical and subclinical hypocalcaemia while having no effect on milk yield or fat-corrected milk.
{"title":"Effect of prepartum dietary-cation anion difference on performance, blood mineral and metabolite concentrations in Holstein dairy cows","authors":"Hazem E M Hassanien, Awad M M Mahmoud, Elsayed Mohammed ABDEL-ROUF, N. Eweedah","doi":"10.21521/mw.6658","DOIUrl":"https://doi.org/10.21521/mw.6658","url":null,"abstract":"Dietary cation-anion difference (DCAD) initiates a compensatory metabolic acidosis, which improves calcium (Ca) absorption and mobilization before calving and minimizes clinical and subclinical hypocalcaemia after calving. The goal of this study was to evaluate how mineral concentrations, blood metabolites, parathyroid hormone (PTH), and productive performance were affected by prepartum dietary cation-anion difference (DCAD mEq [(Na + K – Cl + S)]/kg of dry matter (DM)) in postpartum dairy cows. Forty-eight multiparous Holstein cows ranging from 2 to 5 lactations with an average body weight of 685 ± 10 kg (mean ± SD) were allocated in a randomized block design with three prepartum diets differing in DCAD (0, –100, and –180 mEq/ kg DM). All cows were fed the same postpartum diet and kept on trial for 66 days. Cows fed –180 and –100 mEq DCAD had greater prepartum non-esterified fatty acid (NEFA) concentrations than cows fed 0 mEq DCAD. Cows fed –180 mEq DCAD had greater serum Ca concentrations than cows fed –100 and 0 mEq DCAD. PTH concentrations were greater in cows fed 0 mEq DCAD than in cows fed –100 or –180 mEq DCAD. Cows fed 0 mEq DCAD had higher milk protein and solid-not-fat (SNF) levels than cows fed –100 or –180 mEq DCAD. Treatment and interaction had no effect on milk yield, 3.5% fat-corrected milk (FCM), energy-corrected milk (ECM), milk fat, total solids (TS), lactose, milk urea nitrogen (MUN), magnesium (Mg), sodium (Na), chloride (Cl), potassium (K), beta hydroxybutyric acid (BHBA), and liver or kidney functions. We concluded that adding anionic salts to dairy cows’ diets (–100 and –180 mEq DCAD) improved postpartum Ca availability and reduced clinical and subclinical hypocalcaemia while having no effect on milk yield or fat-corrected milk.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"38 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68095160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study was conducted to investigate the effects of roughage and/or fattening feed rations and CLA-rich fish oil and soybean-supplemented diets on meat quality parameters (pH, color and fatty acids) of crossbred Romanov lambs. As compared to the control group, soybean and fish oil-supplemented groups had almost 3 times greater feed conversion ratios. The amount of feed consumed for 1 kg of live weight during the fattening period was 4.77 kg in the soybean oil-supplemented group, 5.70 kg in the fish oil-supplemented group and 13.33 kg in the control group. In terms of M. longissimus dorsi (MLD) area and thickness, treatment groups all had similar values. Soybean and fish oil-supplemented groups had superior pH and color (L*, a*, b*) values. In the thiobarbituric acid (TBA) test, measuring malonaldehyde (MDA) produced due to the oxidation of fatty acids, results revealed that soybean and fish oil-supplemented groups yielded more ideal outcomes for TBARS values and fatty acid profiles.
{"title":"Effect of fish and soybean oils feed supplementation on the characteristic of Romanov crossbred lamb meat","authors":"M. K. Korkmaz","doi":"10.21521/mw.6649","DOIUrl":"https://doi.org/10.21521/mw.6649","url":null,"abstract":"This study was conducted to investigate the effects of roughage and/or fattening feed rations and CLA-rich fish oil and soybean-supplemented diets on meat quality parameters (pH, color and fatty acids) of crossbred Romanov lambs. As compared to the control group, soybean and fish oil-supplemented groups had almost 3 times greater feed conversion ratios. The amount of feed consumed for 1 kg of live weight during the fattening period was 4.77 kg in the soybean oil-supplemented group, 5.70 kg in the fish oil-supplemented group and 13.33 kg in the control group. In terms of M. longissimus dorsi (MLD) area and thickness, treatment groups all had similar values. Soybean and fish oil-supplemented groups had superior pH and color (L*, a*, b*) values. In the thiobarbituric acid (TBA) test, measuring malonaldehyde (MDA) produced due to the oxidation of fatty acids, results revealed that soybean and fish oil-supplemented groups yielded more ideal outcomes for TBARS values and fatty acid profiles.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68095207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Ziętek, A. Wilczyńska, S. Sajdak, M. Mazur, Łukasz Dąbrosiak, M. Kalinowski, Ł. Adaszek, S. Winiarczyk
Vaccinations for pet rabbits using biological preparations registered in Poland provide protection against three clinical entities: myxomatosis, rabbit haemorrhagic disease types 1 and 2 (RHD1 and RHD2). This article presents an analysis of the number of vaccinations performed in rabbits in the years 2011-2020 at the Clinic of Infectious Diseases of the Faculty of Veterinary Medicine, University of Life Sciences in Lublin. Among the total number of 3304 rabbits admitted to the clinic, 574 visits were for vaccinations, which indicates that the owners of these animals are interested in specific prevention of myxomatosis and RHD. Detailed analysis of the clinic’s records makes it possible to identify certain tendencies, e.g. those associated with the choice of biological preparations or the percentage of immunized animals in different years. Vaccination of rabbits is not difficult for the veterinarian from a technical point of view, it provides excellent protection against lethal infectious diseases, and it can be a source of income for veterinary clinics. For this reason it is worth disseminating knowledge on the vaccination programme for rabbits kept as companion animals among owners of these animals.
{"title":"Use of vaccines in rabbits kept as companion animals based on an analysis of clinical cases at the Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin in 2011-2020","authors":"J. Ziętek, A. Wilczyńska, S. Sajdak, M. Mazur, Łukasz Dąbrosiak, M. Kalinowski, Ł. Adaszek, S. Winiarczyk","doi":"10.21521/mw.6650","DOIUrl":"https://doi.org/10.21521/mw.6650","url":null,"abstract":"Vaccinations for pet rabbits using biological preparations registered in Poland provide protection against three clinical entities: myxomatosis, rabbit haemorrhagic disease types 1 and 2 (RHD1 and RHD2). This article presents an analysis of the number of vaccinations performed in rabbits in the years 2011-2020 at the Clinic of Infectious Diseases of the Faculty of Veterinary Medicine, University of Life Sciences in Lublin. Among the total number of 3304 rabbits admitted to the clinic, 574 visits were for vaccinations, which indicates that the owners of these animals are interested in specific prevention of myxomatosis and RHD. Detailed analysis of the clinic’s records makes it possible to identify certain tendencies, e.g. those associated with the choice of biological preparations or the percentage of immunized animals in different years. Vaccination of rabbits is not difficult for the veterinarian from a technical point of view, it provides excellent protection against lethal infectious diseases, and it can be a source of income for veterinary clinics. For this reason it is worth disseminating knowledge on the vaccination programme for rabbits kept as companion animals among owners of these animals.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68095214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this review was to present the possibilities of minimizing fearfulness and stress in horses by various prophylactic and therapeutic methods. The teaching techniques mentioned in the article (imprint training, habituation, desensitization, counterconditioning) can be successfully used not only during the early development of human-horse interaction, but also during the therapeutic treatment of undesired and stereotypic behaviours. Horses’ activity in the paddock and/or stable can be increased by different types of environmental enrichment (feeding, social, sensory, occupational and physical enrichment). Such environmental variety has a positive influence on equine welfare and can prevent the development of problematic behaviour. Animals living in a highly enriched environment and properly interacting with humans react with lower intensity to environmental stimuli. All these factors have a positive effect on the quality of the human-horse relationship, making the everyday maintenance and use of horses easier and safer.
{"title":"Possibilities of reducing fearfulness and stress in horses by prophylactic methods and behavioural therapies","authors":"M. Budzyńska, M. Jarosz, Joanna Kapustka","doi":"10.21521/mw.6690","DOIUrl":"https://doi.org/10.21521/mw.6690","url":null,"abstract":"The aim of this review was to present the possibilities of minimizing fearfulness and stress in horses by various prophylactic and therapeutic methods. The teaching techniques mentioned in the article (imprint training, habituation, desensitization, counterconditioning) can be successfully used not only during the early development of human-horse interaction, but also during the therapeutic treatment of undesired and stereotypic behaviours. Horses’ activity in the paddock and/or stable can be increased by different types of environmental enrichment (feeding, social, sensory, occupational and physical enrichment). Such environmental variety has a positive influence on equine welfare and can prevent the development of problematic behaviour. Animals living in a highly enriched environment and properly interacting with humans react with lower intensity to environmental stimuli. All these factors have a positive effect on the quality of the human-horse relationship, making the everyday maintenance and use of horses easier and safer.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68097493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haitao Jia, Xiaoyan Zheng, Shuaicheng Li, Jiantao Zhang, Hongbin Wang
Laminitis is regarded as an important underlying cause of lameness disorders, yet its specific pathogenesis remains unclear. Consistent histological changes in cows with laminitis consist in the degradation of the basement membrane (BM). The breakdown of BM is accomplished by numerous proteases, especially MMP-9 and MMP-2. This study recruited 45 cows according to veterinary diagnostic criteria and divided them into three groups: subclinical laminitis cows (SCL, n = 15), chronic laminitis cows (CL, n = 15), and healthy cows (CON, n = 15). After blood samples were collected from the jugular vein, the serum was separated and frozen at –80°C. The serum samples were analyzed by gelatin zymography and reverse zymography to evaluate the activities of MMP-9, MMP-2, TIMP-1, and TIMP-2. In the SCL group, the activity of MMP-9 significantly increased (P <0.01) and the activity of TIMP-1 significantly decreased (P <0.05), compared with those in the CON group, while the activities of MMP-2 and TIMP-2 were not significantly different. In the CL group, the activities of MMP-9 (P <0.001) and MMP-2 (P <0.05) significantly increased, and the activities of TIMP-1 (P <0.01) and TIMP-2 (P <0.05) significantly decreased compared with those in the CON group. This is the first study to report changes in the content of MMP-2 and MMP-9 and their inhibitors, TIMP-2 and TIMP-1, in the serum of dairy cows with laminitis. These results indicate that inadequate regulation of the activities of MMPs and TIMPs in serum may play a role in the development of laminitis in dairy cows.
足板炎被认为是跛行疾病的重要潜在原因，但其具体的发病机制尚不清楚。基底膜炎奶牛的组织学变化主要表现为基底膜的降解。BM的分解是由许多蛋白酶完成的，尤其是MMP-9和MMP-2。本研究按照兽医诊断标准招募45头奶牛，将其分为亚临床板层炎奶牛(SCL, n = 15)、慢性板层炎奶牛(CL, n = 15)和健康奶牛(CON, n = 15) 3组。颈静脉采血后，分离血清，-80℃冷冻。采用明胶酶谱法和反向酶谱法检测血清中MMP-9、MMP-2、TIMP-1和TIMP-2的活性。SCL组与CON组相比，MMP-9活性显著升高(P <0.01)， TIMP-1活性显著降低(P <0.05)，而MMP-2和TIMP-2活性无显著差异。与CON组相比，CL组MMP-9和MMP-2活性显著升高(P <0.001)， TIMP-1和TIMP-2活性显著降低(P <0.05)。这是首次报道奶牛板膜炎血清中MMP-2和MMP-9及其抑制剂TIMP-2和TIMP-1含量变化的研究。上述结果提示，血清中MMPs和TIMPs活性调节不足可能在奶牛板炎的发生过程中起一定作用。
{"title":"Changes in the levels of MMP-9, MMP-2, and their inhibitors in the serum of dairy cows with laminitis","authors":"Haitao Jia, Xiaoyan Zheng, Shuaicheng Li, Jiantao Zhang, Hongbin Wang","doi":"10.21521/mw.6663","DOIUrl":"https://doi.org/10.21521/mw.6663","url":null,"abstract":"Laminitis is regarded as an important underlying cause of lameness disorders, yet its specific pathogenesis remains unclear. Consistent histological changes in cows with laminitis consist in the degradation of the basement membrane (BM). The breakdown of BM is accomplished by numerous proteases, especially MMP-9 and MMP-2. This study recruited 45 cows according to veterinary diagnostic criteria and divided them into three groups: subclinical laminitis cows (SCL, n = 15), chronic laminitis cows (CL, n = 15), and healthy cows (CON, n = 15). After blood samples were collected from the jugular vein, the serum was separated and frozen at –80°C. The serum samples were analyzed by gelatin zymography and reverse zymography to evaluate the activities of MMP-9, MMP-2, TIMP-1, and TIMP-2. In the SCL group, the activity of MMP-9 significantly increased (P <0.01) and the activity of TIMP-1 significantly decreased (P <0.05), compared with those in the CON group, while the activities of MMP-2 and TIMP-2 were not significantly different. In the CL group, the activities of MMP-9 (P <0.001) and MMP-2 (P <0.05) significantly increased, and the activities of TIMP-1 (P <0.01) and TIMP-2 (P <0.05) significantly decreased compared with those in the CON group. This is the first study to report changes in the content of MMP-2 and MMP-9 and their inhibitors, TIMP-2 and TIMP-1, in the serum of dairy cows with laminitis. These results indicate that inadequate regulation of the activities of MMPs and TIMPs in serum may play a role in the development of laminitis in dairy cows.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68096049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the present review is to demonstrate the possibility of limiting antibiotic therapy in intensive poultry production through the use of various immunomodulators. In an era of increasing resistance of microorganisms to antimicrobial agents, it is particularly important to improve the efficiency of the immune system, which is indispensable for birds to survive in an environment where this system is constantly exposed to a number of stimuli that directly or indirectly affect its functioning. This is all the more important as the health of birds kept under intensive systems depends mainly on the functional status of their immune system, which determines the level of postvaccination immunity and the effectiveness of treatment. That is because its proper function is needed for the elimination of pathogenic microorganisms, stimulation of repair processes in damaged tissues and protection against reinfection. This paper focuses on the possibilities of modulating immune mechanisms and correcting the reactivity of the immunological system in poultry by using natural or synthetic immunomodulators. The results presented here suggest that methisoprinol and β-glucans are effective in modulating immune processes in turkeys and may find practical application in mass rearing of these birds: β-glucans mainly in prophylactic programmes, whereas methisoprinol both in prevention and treatment of diseases of viral etiology occurring with immunosuppression. It has also been shown that phytoncides contained in well-composed complementary feeds show immunomodulatory effects in broiler chickens and turkeys and are effective in the prevention and treatment of black head disease in turkeys. Considering the key role of the immune system in fighting pathogens, it should be concluded that synthetic and natural immunomodulators, including phytoncides used in the prevention and treatment of poultry diseases, can effectively reduce and, in some cases, replace or support antibiotic therapy.
{"title":"Immunomodulation as a tool to reduce antibiotic therapy in intensive poultry production","authors":"Bartłomiej Tykałowski, A. Koncicki","doi":"10.21521/mw.6681","DOIUrl":"https://doi.org/10.21521/mw.6681","url":null,"abstract":"The aim of the present review is to demonstrate the possibility of limiting antibiotic therapy in intensive poultry production through the use of various immunomodulators. In an era of increasing resistance of microorganisms to antimicrobial agents, it is particularly important to improve the efficiency of the immune system, which is indispensable for birds to survive in an environment where this system is constantly exposed to a number of stimuli that directly or indirectly affect its functioning. This is all the more important as the health of birds kept under intensive systems depends mainly on the functional status of their immune system, which determines the level of postvaccination immunity and the effectiveness of treatment. That is because its proper function is needed for the elimination of pathogenic microorganisms, stimulation of repair processes in damaged tissues and protection against reinfection. This paper focuses on the possibilities of modulating immune mechanisms and correcting the reactivity of the immunological system in poultry by using natural or synthetic immunomodulators. The results presented here suggest that methisoprinol and β-glucans are effective in modulating immune processes in turkeys and may find practical application in mass rearing of these birds: β-glucans mainly in prophylactic programmes, whereas methisoprinol both in prevention and treatment of diseases of viral etiology occurring with immunosuppression. It has also been shown that phytoncides contained in well-composed complementary feeds show immunomodulatory effects in broiler chickens and turkeys and are effective in the prevention and treatment of black head disease in turkeys. Considering the key role of the immune system in fighting pathogens, it should be concluded that synthetic and natural immunomodulators, including phytoncides used in the prevention and treatment of poultry diseases, can effectively reduce and, in some cases, replace or support antibiotic therapy.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68097024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Kahraman, Aydın Daş, G. Güngören, B. D. Daş, H. Yalçın, I. Koyuncu, Ş. Akmeşe
This study aimed to determine the metabolomic characteristics associated with the fattening performance of the Awassi lamb breed under intensive fattening for 90 days. Twenty-four lambs were used in the research. The lambs were divided into two groups according to their fattening performance (good fattening performance, n = 12, and poor fattening performance, n = 12), and their metabolomic properties were evaluated. The differences between the two research groups in the amino acids of alloisoleucine, aspartic acid, histidine, hydroxylysine, isoleucine, lysine, methionine, phenylalanine, tryptophan, valine, and 1-methylhistidine were found to be statistically significant (P ≤ 0.001). Moderately significant negative correlations were found between daily concentrate feed intake and 3-methylhistidine (r = −0.469; P = 0.021), hydroxylysine (r = −0.408; P = 0.048), and serotonin (r= −0.467; P = 0.021); as well as between the average daily weight gain (ADWG) and alloisoleucine (r = −0.528; P = 0.008), 3-methylhistidine (r = −0.440; P = 0.032), and hydroxylysine (r = −0.577; P = 0.003). A moderate positive correlation was found between hydroxyisovalerylcarnitine and ADWG (r = 0.476; P = 0.019), and a negative correlation was found between hydroxyisovalerylcarnitine and the feed conversion ratio (r = −0.430; P = 0.036). Pathway analysis revealed that the most important biological pathway was the phenylalanine, tyrosine, and tryptophan biosynthesis pathway. The results of the research reveal the potential for plasma free amino acid and carnitine profiles to be used as candidate biomarkers in the evaluation of fattening performance in lambs.
{"title":"The use of metabolomics tools in the evaluation of the fattening performance of lambs","authors":"M. Kahraman, Aydın Daş, G. Güngören, B. D. Daş, H. Yalçın, I. Koyuncu, Ş. Akmeşe","doi":"10.21521/mw.6697","DOIUrl":"https://doi.org/10.21521/mw.6697","url":null,"abstract":"This study aimed to determine the metabolomic characteristics associated with the fattening performance of the Awassi lamb breed under intensive fattening for 90 days. Twenty-four lambs were used in the research. The lambs were divided into two groups according to their fattening performance (good fattening performance, n = 12, and poor fattening performance, n = 12), and their metabolomic properties were evaluated. The differences between the two research groups in the amino acids of alloisoleucine, aspartic acid, histidine, hydroxylysine, isoleucine, lysine, methionine, phenylalanine, tryptophan, valine, and 1-methylhistidine were found to be statistically significant (P ≤ 0.001). Moderately significant negative correlations were found between daily concentrate feed intake and 3-methylhistidine (r = −0.469; P = 0.021), hydroxylysine (r = −0.408; P = 0.048), and serotonin (r= −0.467; P = 0.021); as well as between the average daily weight gain (ADWG) and alloisoleucine (r = −0.528; P = 0.008), 3-methylhistidine (r = −0.440; P = 0.032), and hydroxylysine (r = −0.577; P = 0.003). A moderate positive correlation was found between hydroxyisovalerylcarnitine and ADWG (r = 0.476; P = 0.019), and a negative correlation was found between hydroxyisovalerylcarnitine and the feed conversion ratio (r = −0.430; P = 0.036). Pathway analysis revealed that the most important biological pathway was the phenylalanine, tyrosine, and tryptophan biosynthesis pathway. The results of the research reveal the potential for plasma free amino acid and carnitine profiles to be used as candidate biomarkers in the evaluation of fattening performance in lambs.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68098866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to present the characteristics of and to predict subclinical hypocalcemia in dairy cows during the transition period using blood analytes. We examined fluctuations in plasma calcium (Ca), phosphorus (P), bone metabolic markers carboxy-terminal telopeptide of type I collagen (CTX), fibroblast growth factor (FGF23), 1,25(OH)2D3, parathyroid hormone, and other blood biochemical analytes from prepartum week 2 to postpartum day 14 in 116 multiparous high-producing Holstein cows from a free-stall barn dairy farm. With a plasma concentration of Ca <2.0 mmol/L as a criterion for the diagnosis of subclinical hypocalcemia, 64 cows were classified as normocalcemic, and 52 cows as subclinically hypocalcemic. Among the 52 hypocalcemic cows, 50 were detected on postpartum days 1 or 3, and 2 on postpartum day. The subclinically hypocalcemic cows were in a state of low bone turnover in the prepartum period, with low plasma concentrations of Ca and CTX. The subclinically hypocalcemic cows showed signs of a P regulation disorder in the prepartum period. This was marked by high plasma concentrations of P and low concentrations of 1,25(OH)2D3 and FGF23, which is also considered to be the cause of the low bone turnover. The results of a multiple logistic regression model showed that prepartum plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows, using the model equation 38.8-0.052*FGF23-0.492*CTX-10.645*Ca, with a score of > 0 considered as an indication of increased risk of subclinical hypocalcemia after calving. The scoring rule had an accuracy of 79.3%, sensitivity of 76.9%, and specificity of 81.3%. The plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows.
{"title":"Characteristics and prediction of subclinical hypocalcemia in dairy cows during the transition period using blood analytes","authors":"Xinru Ma, Changhong Gao, Mingmao Yang, Bingbing Zhang, Chuang Xu, Wei Yang","doi":"10.21521/mw.6607","DOIUrl":"https://doi.org/10.21521/mw.6607","url":null,"abstract":"This study aimed to present the characteristics of and to predict subclinical hypocalcemia in dairy cows during the transition period using blood analytes. We examined fluctuations in plasma calcium (Ca), phosphorus (P), bone metabolic markers carboxy-terminal telopeptide of type I collagen (CTX), fibroblast growth factor (FGF23), 1,25(OH)2D3, parathyroid hormone, and other blood biochemical analytes from prepartum week 2 to postpartum day 14 in 116 multiparous high-producing Holstein cows from a free-stall barn dairy farm. With a plasma concentration of Ca <2.0 mmol/L as a criterion for the diagnosis of subclinical hypocalcemia, 64 cows were classified as normocalcemic, and 52 cows as subclinically hypocalcemic. Among the 52 hypocalcemic cows, 50 were detected on postpartum days 1 or 3, and 2 on postpartum day. The subclinically hypocalcemic cows were in a state of low bone turnover in the prepartum period, with low plasma concentrations of Ca and CTX. The subclinically hypocalcemic cows showed signs of a P regulation disorder in the prepartum period. This was marked by high plasma concentrations of P and low concentrations of 1,25(OH)2D3 and FGF23, which is also considered to be the cause of the low bone turnover. The results of a multiple logistic regression model showed that prepartum plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows, using the model equation 38.8-0.052*FGF23-0.492*CTX-10.645*Ca, with a score of > 0 considered as an indication of increased risk of subclinical hypocalcemia after calving. The scoring rule had an accuracy of 79.3%, sensitivity of 76.9%, and specificity of 81.3%. The plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68092924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pulmonary parasitic diseases have become a frequent feline condition. Aelurostrongylus abstrusus, Troglostrongylus brevior and Capillaria aerophila appear to be the main pathogenic factors. Felines that are affected may display respiratory as well as non-specific symptoms. Diagnostic methods include copromicroscopic, serological and molecular detection, whereas the treatment should be both symptomatic and elective.
{"title":"Feline pulmonary nematodes; new challenges for veterinary practitioners","authors":"Karolina Mizera","doi":"10.21521/mw.6613","DOIUrl":"https://doi.org/10.21521/mw.6613","url":null,"abstract":"Pulmonary parasitic diseases have become a frequent feline condition. Aelurostrongylus abstrusus, Troglostrongylus brevior and Capillaria aerophila appear to be the main pathogenic factors. Felines that are affected may display respiratory as well as non-specific symptoms. Diagnostic methods include copromicroscopic, serological and molecular detection, whereas the treatment should be both symptomatic and elective.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68093010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The article reviews the history of BT occurrence in Europe and its present status. It describes the distribution of BT in Europe before 1998, the emergence of BTV in southern and eastern Europe in 1998-2006 and the epidemiology of BT in north-western Europe after 2006. Up to 1998, sporadic cases of BT were noted in Cyprus, on the Iberian Peninsula and on several Greek islands. However, since 1998, probably due to climatic changes, BTV has spread northwards into the Mediterranean Basin, where five BTV serotypes (1, 2, 4, 9 and 16) have been identified. In August 2006, BTV passed for the first time latitude 50°N, and BT outbreaks caused by BTV serotype 8 occurred in the Netherlands, Belgium, Germany, France and Luxembourg. Mass vaccination campaigns implemented in Europe in the spring of 2008 quickly limited the spread of disease caused by BTV-8, and it was eradicated by 2011. However, after a 3-year break, in September 2015, BTV-8 re-emerged in Europe, in central France, and subsequently spread throughout the entire country. In the following years, BTV-8 outbreaks were found in Switzerland, Germany, Belgium and Spain. In addition to BTV-8 outbreaks, BTV serotypes 1, 2, 4, 9 and 16 have recently circulated in Europe. As revealed by phylogeographic inference, the recent spread of BTV in Europe is a consequence of climatic, landscape and vertebrate host factors
{"title":"Bluetongue virus in Europe: the current epidemiological situation","authors":"W. Niedbalski","doi":"10.21521/mw.6619","DOIUrl":"https://doi.org/10.21521/mw.6619","url":null,"abstract":"The article reviews the history of BT occurrence in Europe and its present status. It describes the distribution of BT in Europe before 1998, the emergence of BTV in southern and eastern Europe in 1998-2006 and the epidemiology of BT in north-western Europe after 2006. Up to 1998, sporadic cases of BT were noted in Cyprus, on the Iberian Peninsula and on several Greek islands. However, since 1998, probably due to climatic changes, BTV has spread northwards into the Mediterranean Basin, where five BTV serotypes (1, 2, 4, 9 and 16) have been identified. In August 2006, BTV passed for the first time latitude 50°N, and BT outbreaks caused by BTV serotype 8 occurred in the Netherlands, Belgium, Germany, France and Luxembourg. Mass vaccination campaigns implemented in Europe in the spring of 2008 quickly limited the spread of disease caused by BTV-8, and it was eradicated by 2011. However, after a 3-year break, in September 2015, BTV-8 re-emerged in Europe, in central France, and subsequently spread throughout the entire country. In the following years, BTV-8 outbreaks were found in Switzerland, Germany, Belgium and Spain. In addition to BTV-8 outbreaks, BTV serotypes 1, 2, 4, 9 and 16 have recently circulated in Europe. As revealed by phylogeographic inference, the recent spread of BTV in Europe is a consequence of climatic, landscape and vertebrate host factors","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68093311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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