Canine Hip Dysplasia (CHD) is considered to be one of the most common orthopaedic diseases and it consists of coxofemoral joint incongruence leading to femoral head subluxation and osteoarthritic changes. The affected dogs tend to present progressive pain and mobility issues. The widely used CHD managing strategies, among others, include pelvic osteotomy techniques. In recent years, great efforts have been made to improve the surgical procedure and reduce the rate of complications, which seems to be a possibility due to the introduction of constructional changes in modern TPO/DPO plates.
{"title":"Pelvic osteotomy techniques in the management of canine hip dysplasia – evolution of the treatment paradigm","authors":"Turek Wiktor, Aleksiewicz Roman, Albu Kateryna","doi":"10.21521/mw.6793","DOIUrl":"https://doi.org/10.21521/mw.6793","url":null,"abstract":"Canine Hip Dysplasia (CHD) is considered to be one of the most common orthopaedic diseases and it consists of coxofemoral joint incongruence leading to femoral head subluxation and osteoarthritic changes. The affected dogs tend to present progressive pain and mobility issues. The widely used CHD managing strategies, among others, include pelvic osteotomy techniques. In recent years, great efforts have been made to improve the surgical procedure and reduce the rate of complications, which seems to be a possibility due to the introduction of constructional changes in modern TPO/DPO plates.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68107648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the study was to analyse the impact of inbreeding on the frequency of hereditary diseases and the number of genetically tested dogs. The pedigrees of 100 Chinese Crested dogs from Polish Kennel Club and information about genetic tests for hereditary eye diseases and other veterinary diagnoses were collected. Inbreeding coefficients and relatedness were estimated for all dogs examined. The relationship between the level of inbreeding and genetic testing was analysed with logistic regression. The relationship between the occurrence of eye disease carriers and sex or the level of inbreeding was also tested. A significant relationship (P < 0.01) was found between inbreeding and the number of animals genetically tested for PLL eye disease. The effect of sex or the level of inbreeding on the eye disease carrier status was non-significant (P > 0.05). However, in some inbred animals the status of the eye disease carrier could be connected with inbreeding, although this needs further research. We found that most of the dogs had related parents and genetic defects. We also found that the breeders often used related dogs, which reduced the genetic diversity of the group and caused hereditary diseases. We suggest that Chinese Crested dog breeders be more open about publishing DNA-test results, which is fundamental for the health of the breed.
{"title":"Effect of inbreeding on the occurrence of genetic defects in Chinese Crested dogs","authors":"Agnieszka Bartnikowska, J. Kania-Gierdziewicz","doi":"10.21521/mw.6765","DOIUrl":"https://doi.org/10.21521/mw.6765","url":null,"abstract":"The aim of the study was to analyse the impact of inbreeding on the frequency of hereditary diseases and the number of genetically tested dogs. The pedigrees of 100 Chinese Crested dogs from Polish Kennel Club and information about genetic tests for hereditary eye diseases and other veterinary diagnoses were collected. Inbreeding coefficients and relatedness were estimated for all dogs examined. The relationship between the level of inbreeding and genetic testing was analysed with logistic regression. The relationship between the occurrence of eye disease carriers and sex or the level of inbreeding was also tested. A significant relationship (P < 0.01) was found between inbreeding and the number of animals genetically tested for PLL eye disease. The effect of sex or the level of inbreeding on the eye disease carrier status was non-significant (P > 0.05). However, in some inbred animals the status of the eye disease carrier could be connected with inbreeding, although this needs further research. We found that most of the dogs had related parents and genetic defects. We also found that the breeders often used related dogs, which reduced the genetic diversity of the group and caused hereditary diseases. We suggest that Chinese Crested dog breeders be more open about publishing DNA-test results, which is fundamental for the health of the breed.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68105263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Welz, Przemysław Łoś, Renata Kondrat, Blanka Orłowska, A. Didkowska, K. Anusz
Tuberculosis in animals is an infectious and contagious disease, caused by acid-fast bacilli of the Mycobacterium tuberculosis complex. The disease has been confirmed in Poland in farm and wild animals. Among the latter the largest number of cases was diagnosed in free-ranging European bison in the Bieszczady Mountains. The disease has also been present there since 2013 in the wild boar population. From April 21, 2021, in accordance with EU Regulation 2016/429, tuberculosis in European bison is a disease that is subject to mandatory eradication in all EU Member States. In Poland and in most EU countries where free-ranging European bison herds exist, no strategy has yet been developed to combat tuberculosis outbreaks in this species. To date, in Podkarpackie Voivodship eradication measures of bison tuberculosis have been undertaken in a framework of interdisciplinary cooperation of employees of the State Forests and the Veterinary Inspection, supported by representatives of the sciences. The article presents the legal status and the administrative aspects of the issue, as well as experiences and practical solutions of tuberculosis eradication in free-living European bison herds which have proven themselves in field conditions. The conclusions regarding an eradication strategy and the needs of tuberculosis monitoring are also presented in this article, which, apart from wild bison herds, takes into account other wild animal species and farm cattle from areas and buffer zones of bison herds infected with tuberculosis.
{"title":"Combating tuberculosis in European bison in the Bieszczady Mountains - administrative aspect","authors":"M. Welz, Przemysław Łoś, Renata Kondrat, Blanka Orłowska, A. Didkowska, K. Anusz","doi":"10.21521/mw.6756","DOIUrl":"https://doi.org/10.21521/mw.6756","url":null,"abstract":"Tuberculosis in animals is an infectious and contagious disease, caused by acid-fast bacilli of the Mycobacterium tuberculosis complex. The disease has been confirmed in Poland in farm and wild animals. Among the latter the largest number of cases was diagnosed in free-ranging European bison in the Bieszczady Mountains. The disease has also been present there since 2013 in the wild boar population. From April 21, 2021, in accordance with EU Regulation 2016/429, tuberculosis in European bison is a disease that is subject to mandatory eradication in all EU Member States. In Poland and in most EU countries where free-ranging European bison herds exist, no strategy has yet been developed to combat tuberculosis outbreaks in this species. To date, in Podkarpackie Voivodship eradication measures of bison tuberculosis have been undertaken in a framework of interdisciplinary cooperation of employees of the State Forests and the Veterinary Inspection, supported by representatives of the sciences. The article presents the legal status and the administrative aspects of the issue, as well as experiences and practical solutions of tuberculosis eradication in free-living European bison herds which have proven themselves in field conditions. The conclusions regarding an eradication strategy and the needs of tuberculosis monitoring are also presented in this article, which, apart from wild bison herds, takes into account other wild animal species and farm cattle from areas and buffer zones of bison herds infected with tuberculosis.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68105335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study was to investigate whether a CT scan provides accurate bone surface information for feline bone model development. The second part of study consisted of 3D printing of feline femoral bone models with and without femoral neck fractures (31-B1 and 31-B2 in AO VET classification), as well as the development and 3D printing of drill guides for treatment of femoral neck fractures. The study was carried out on eight models of femoral bones and four drill guides. Initially, trial models of the right and left femurs without neck fractures and trial drill guides were used. Radiographs showed that the use of the prototype guides made it possible to drill holes in the axes of the necks of the femurs. Then, after assessing the correct operation of the guides and improving their adhesion to the bone surface by smoothing the inner surfaces of the guide bases, final bone models without femoral neck fracture, models with fractures 31-B1 and 31-B2, and final drill guides were printed. All models featured a 2.7 × 30 mm positional cortical screw. Radiographs of the models, made after inserting screws, showed that the implants were placed as intended. Also in the longitudinal sections of the heads and necks of the femoral bones of the models without fractures, the implants were positioned in the intended places.
{"title":"Accuracy of CAD/CAM and 3D printing in the treatment of feline femoral neck fracture","authors":"","doi":"10.21521/mw.6772","DOIUrl":"https://doi.org/10.21521/mw.6772","url":null,"abstract":"The aim of this study was to investigate whether a CT scan provides accurate bone surface information for feline bone model development. The second part of study consisted of 3D printing of feline femoral bone models with and without femoral neck fractures (31-B1 and 31-B2 in AO VET classification), as well as the development and 3D printing of drill guides for treatment of femoral neck fractures. The study was carried out on eight models of femoral bones and four drill guides. Initially, trial models of the right and left femurs without neck fractures and trial drill guides were used. Radiographs showed that the use of the prototype guides made it possible to drill holes in the axes of the necks of the femurs. Then, after assessing the correct operation of the guides and improving their adhesion to the bone surface by smoothing the inner surfaces of the guide bases, final bone models without femoral neck fracture, models with fractures 31-B1 and 31-B2, and final drill guides were printed. All models featured a 2.7 × 30 mm positional cortical screw. Radiographs of the models, made after inserting screws, showed that the implants were placed as intended. Also in the longitudinal sections of the heads and necks of the femoral bones of the models without fractures, the implants were positioned in the intended places.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68106718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to determine the effects of the addition of almond hull to corn silage on silage quality, fermentation properties and in vitro organic matter digestion (IVOMD). While corn silage without additives constituted the control group in the study, silages with almond hull added at the levels of 0.5%, 1%, 1.5%, 2% and 2.5% formed the experimental groups.The addition of almond hull caused an increase in the IVOMD and metabolizable energy (ME) values of the silages compared to the control group. For all the experimental groups, the methane (CH4) values of the silages were lower than the values of the control group. The silage pH range of all silage groups was in the range of 3.62-3.70. The lactic acid (LA) and acetic acid (AA) values of the silages, on the other hand, were higher in all experimental groups compared with the values of the control group, and the highest values were observed in the group with the 1% almond hull addition. No propionic acid (PA), butyric acid (BA), or mold was detected in any of the silage groups. The yeast values, on the other hand, were lower in all silages that contained added almond hulls than the in the control group. The amount of CO2 produced in the silage groups decreased in parallel with the increase in almond hull. This study will enable more use and evaluation of almond hulls in animal nutrition due to its positive effect on fermentation.
{"title":"Effect of almond (Prunus dulcis) hull addition to corn silage on silage quality, silage fermentation properties and in vitro digestibility","authors":"AY S.S.","doi":"10.21521/mw.6784","DOIUrl":"https://doi.org/10.21521/mw.6784","url":null,"abstract":"This study aimed to determine the effects of the addition of almond hull to corn silage on silage quality, fermentation properties and in vitro organic matter digestion (IVOMD). While corn silage without additives constituted the control group in the study, silages with almond hull added at the levels of 0.5%, 1%, 1.5%, 2% and 2.5% formed the experimental groups.The addition of almond hull caused an increase in the IVOMD and metabolizable energy (ME) values of the silages compared to the control group. For all the experimental groups, the methane (CH4) values of the silages were lower than the values of the control group. The silage pH range of all silage groups was in the range of 3.62-3.70. The lactic acid (LA) and acetic acid (AA) values of the silages, on the other hand, were higher in all experimental groups compared with the values of the control group, and the highest values were observed in the group with the 1% almond hull addition. No propionic acid (PA), butyric acid (BA), or mold was detected in any of the silage groups. The yeast values, on the other hand, were lower in all silages that contained added almond hulls than the in the control group. The amount of CO2 produced in the silage groups decreased in parallel with the increase in almond hull. This study will enable more use and evaluation of almond hulls in animal nutrition due to its positive effect on fermentation.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68107749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Magdalena MORAWSKA-KOZŁOWSKA, Y. Zhalniarovich, M. Mieszkowska
Tibial tuberosity avulsion fractures represent a small proportion of proximal tibial fractures in dogs. We distinguish between different types of this trauma. This disease is commonly encountered in young and skeletally immature animals. In the past, dogs with tibial tuberosity avulsion fractures were not treated, which resulted in chronic lameness. At present, various therapeutic methods are available for managing this disease. The aim of this article was to present the therapeutic protocols for managing tibial tuberosity avulsion fractures in dogs. The present article reviews the data regarding the treatment of tibial tuberosity avulsion fractures in dogs. Many veterinarians are reluctant to use conservative methods in the treatment of tibial tuberosity avulsion fractures due to the uncertain outcome and possible fracture progression. There are many surgical treatment options, but Kirschner wires with a tension band are the surgical method of choice for managing the problem. This article also contains a detailed description of the surgical procedure with the recommended method. The manuscript additionally touches on rehabilitation and conservative treatment of tibial tuberosity avulsion fractures.
{"title":"Systematic review regarding treatment of tibial tuberosity avulsion fractures in young dogs","authors":"Magdalena MORAWSKA-KOZŁOWSKA, Y. Zhalniarovich, M. Mieszkowska","doi":"10.21521/mw.6801","DOIUrl":"https://doi.org/10.21521/mw.6801","url":null,"abstract":"Tibial tuberosity avulsion fractures represent a small proportion of proximal tibial fractures in dogs. We distinguish between different types of this trauma. This disease is commonly encountered in young and skeletally immature animals. In the past, dogs with tibial tuberosity avulsion fractures were not treated, which resulted in chronic lameness. At present, various therapeutic methods are available for managing this disease. The aim of this article was to present the therapeutic protocols for managing tibial tuberosity avulsion fractures in dogs. The present article reviews the data regarding the treatment of tibial tuberosity avulsion fractures in dogs. Many veterinarians are reluctant to use conservative methods in the treatment of tibial tuberosity avulsion fractures due to the uncertain outcome and possible fracture progression. There are many surgical treatment options, but Kirschner wires with a tension band are the surgical method of choice for managing the problem. This article also contains a detailed description of the surgical procedure with the recommended method. The manuscript additionally touches on rehabilitation and conservative treatment of tibial tuberosity avulsion fractures.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68108789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sobczyńska-Rak, B. Żylińska, Ł. Jarosz, A. Ciszewski, B. Kaczmarek
Xanthoma is an interesting, inflammatory, noncancerous lesion that is rarely diagnosed in companion animals, although it has been reported in a number of domestic and wild species. Macroscopically, it can range from a few millimeter plaques or nodules to even several-centimeter masses. It usually occurs within the skin, but has been diagnosed in almost all other internal systems and organs. As the name suggests, xanthoma most often is of yellow color, but whitish and red forms are also encountered. Although inconspicuous, the presence of xanthoma is often reflected in disorders of lipid and lipoprotein metabolism, which affects the entire body. Therefore, in patients with even a small xanthoma on the skin, coexisting metabolic and endocrine disorders should be excluded, such as: hyperlipidemia, hypercholesterolaemia, hypothyroidism, hyperadrenocorticism and diabetes.
{"title":"Xanthoma in different species - an unusual tumor with many faces.","authors":"A. Sobczyńska-Rak, B. Żylińska, Ł. Jarosz, A. Ciszewski, B. Kaczmarek","doi":"10.21521/mw.6803","DOIUrl":"https://doi.org/10.21521/mw.6803","url":null,"abstract":"Xanthoma is an interesting, inflammatory, noncancerous lesion that is rarely diagnosed in companion animals, although it has been reported in a number of domestic and wild species. Macroscopically, it can range from a few millimeter plaques or nodules to even several-centimeter masses. It usually occurs within the skin, but has been diagnosed in almost all other internal systems and organs. As the name suggests, xanthoma most often is of yellow color, but whitish and red forms are also encountered. Although inconspicuous, the presence of xanthoma is often reflected in disorders of lipid and lipoprotein metabolism, which affects the entire body. Therefore, in patients with even a small xanthoma on the skin, coexisting metabolic and endocrine disorders should be excluded, such as: hyperlipidemia, hypercholesterolaemia, hypothyroidism, hyperadrenocorticism and diabetes.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68109901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Wadowska, I. Łuszczewska-Sierakowska, M. Dzierzęcka
The lumbosacral region of the spine is most susceptible to pathology in large breed dogs. The most common pathologies of this segment include intervertebral disk discopathy, distortion of vertebral vertebrae, narrowing of the lumbosacral canal and congenital defects of the spine. This area is most commonly affected by physical trauma or aging-related conditions leading to a wide range of symptoms, such as pain and loss of mobility.
{"title":"Most prevalent spinal disease of in dogs","authors":"I. Wadowska, I. Łuszczewska-Sierakowska, M. Dzierzęcka","doi":"10.21521/mw.6805","DOIUrl":"https://doi.org/10.21521/mw.6805","url":null,"abstract":"The lumbosacral region of the spine is most susceptible to pathology in large breed dogs. The most common pathologies of this segment include intervertebral disk discopathy, distortion of vertebral vertebrae, narrowing of the lumbosacral canal and congenital defects of the spine. This area is most commonly affected by physical trauma or aging-related conditions leading to a wide range of symptoms, such as pain and loss of mobility.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68109958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pathologically changed pattern of gonadotropin secretion, responsible for ovulation disorders in fatty ewes, may result from the prolonged increase in leptin concentration as well as from diminution of leptin receptors expression in anterior pituitary cells. Leptin acting peripherally reduces the secretion of insulin – the potent inhibitor of lipolysis. Consequently, an increment in plasma fatty acids level is observed. It was also found that in ewe lambs born to obese sheep carrying twins or triplets, a high plasma level of saturated fatty acids (SFA) is in positive correlation with the delay in puberty. However, the relationship between SFA and gonadotropin secretion from the ovine pituitary cells in pubescent ewe lambs is not clear. Therefore, the aim of the study was to establish the effect of SFA on GnRH-induced secretion of FSH and LH. Pituitary glands were isolated from 7 month old ewe lambs. Pituitary cells were cultured in McCoy 5A medium without GnRH and SFA (negative control), with GnRH only (positive control), with GnRH and 10–9-10–3 M/l of the butyric (C4:0), caprylic (C8:0), lauric (C12:0), palmitic (C16:0) or stearic acid (C18:0). After 2 or 6 h of exposure to SFA followed by 2, 6, 12, 18, 24 or 30 h incubation, the media for LH and FSH analysis were collected. It was found that all used SFA reduce GnRH-induced LH and FSH secretion from pituitary cells in vitro. The most significant (P ≤ 0.05) suppressive effect was observed after 6 h exposure of cells to 10–3 M/l of caprylic acid, 10–4 M/l of palmitic acid and 10–4 M/l of stearic acid compared to the positive control.
{"title":"Use of rapid immunochromatographic tests and PCR for the detection of vaccine viruses (CPV, CDV CAV) in faeces and conjunctival sac swabs of vaccinated dogs","authors":"NATALIA SZYSIAK, URSZULA KOSIOR-KORZECKA, VINCENZO LONGO, ANDREA CAVALLERO, BARTŁOMIEJ SZYMCZAK, AGNIESZKA FURMAŃCZYK-GNYP, DOMINIKA NGUYEN NGOC, ANETA NOWAKIEWICZ, IWONA PUZIO, BARBARA SURÓWKA, NATALIA MINAKOW","doi":"10.21521/mw.6837","DOIUrl":"https://doi.org/10.21521/mw.6837","url":null,"abstract":"The pathologically changed pattern of gonadotropin secretion, responsible for ovulation disorders in fatty ewes, may result from the prolonged increase in leptin concentration as well as from diminution of leptin receptors expression in anterior pituitary cells. Leptin acting peripherally reduces the secretion of insulin – the potent inhibitor of lipolysis. Consequently, an increment in plasma fatty acids level is observed. It was also found that in ewe lambs born to obese sheep carrying twins or triplets, a high plasma level of saturated fatty acids (SFA) is in positive correlation with the delay in puberty. However, the relationship between SFA and gonadotropin secretion from the ovine pituitary cells in pubescent ewe lambs is not clear. Therefore, the aim of the study was to establish the effect of SFA on GnRH-induced secretion of FSH and LH. Pituitary glands were isolated from 7 month old ewe lambs. Pituitary cells were cultured in McCoy 5A medium without GnRH and SFA (negative control), with GnRH only (positive control), with GnRH and 10–9-10–3 M/l of the butyric (C4:0), caprylic (C8:0), lauric (C12:0), palmitic (C16:0) or stearic acid (C18:0). After 2 or 6 h of exposure to SFA followed by 2, 6, 12, 18, 24 or 30 h incubation, the media for LH and FSH analysis were collected. It was found that all used SFA reduce GnRH-induced LH and FSH secretion from pituitary cells in vitro. The most significant (P ≤ 0.05) suppressive effect was observed after 6 h exposure of cells to 10–3 M/l of caprylic acid, 10–4 M/l of palmitic acid and 10–4 M/l of stearic acid compared to the positive control.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136305777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ANNA DIDKOWSKA, PIOTR ŻMUDA, BLANKA ORŁOWSKA, KRZYSZTOF ANUSZ
Mycobacteria infections in cats include tuberculosis (caused by Mycobacterium bovis and Mycobacterium microti) and mycobacteriosis caused by non-tuberculous mycobacteria (NTM). The aim of the paper is to present the latest reports on mycobacterial infections in cats and place emphasis on their impact on the health of their owners. The reviewers looked for papers about mycobacterial infections in cats in PubMed and Google Scholar from any date from January 2014 to June 2023. The search used the following keywords: cat, feline, tuberculosis, and mycobacteria. Papers were evaluated for their value to science and their applicability. Papers published in recent years have shown that mycobacterial infections in cats should still be considered in a differential diagnosis when many clinical signs present and they are mainly skin and ocular symptoms. An epidemiological investigation of these infections is highly important because cases were reported also in low-risk regions. Mycobacterial infections pose a risk to humans. The degree of risk depends on many factors, such as the species of mycobacteria, the closeness of animal-owner contact, and the immune status of the owner. The greatest risk are still believed to be M. bovis infections; however, NTM infections should also raise a concern, especially in high-risk groups.
{"title":"Mycobacterial infections in cats (Felis catus) as a potential threat to humans – a review 2014–2023","authors":"ANNA DIDKOWSKA, PIOTR ŻMUDA, BLANKA ORŁOWSKA, KRZYSZTOF ANUSZ","doi":"10.21521/mw.6842","DOIUrl":"https://doi.org/10.21521/mw.6842","url":null,"abstract":"Mycobacteria infections in cats include tuberculosis (caused by Mycobacterium bovis and Mycobacterium microti) and mycobacteriosis caused by non-tuberculous mycobacteria (NTM). The aim of the paper is to present the latest reports on mycobacterial infections in cats and place emphasis on their impact on the health of their owners. The reviewers looked for papers about mycobacterial infections in cats in PubMed and Google Scholar from any date from January 2014 to June 2023. The search used the following keywords: cat, feline, tuberculosis, and mycobacteria. Papers were evaluated for their value to science and their applicability. Papers published in recent years have shown that mycobacterial infections in cats should still be considered in a differential diagnosis when many clinical signs present and they are mainly skin and ocular symptoms. An epidemiological investigation of these infections is highly important because cases were reported also in low-risk regions. Mycobacterial infections pose a risk to humans. The degree of risk depends on many factors, such as the species of mycobacteria, the closeness of animal-owner contact, and the immune status of the owner. The greatest risk are still believed to be M. bovis infections; however, NTM infections should also raise a concern, especially in high-risk groups.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135662019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：