M. Adaszyńska-Skwirzyńska, S. Zych, D. Szczerbińska
The present study investigated the antimicrobial activity of enrofloxacin in combination with lavender (Lavandula angustifolia) essential oil against three serotypes of Salmonella: Salmonella Enteritidis ATCC 13076, Salmonella Gallinarum biovar Pullorum ATCC 13036, Salmonella Typhimurium ATCC 14028 and Salmonella Typhimurium – a moderately sensitive monophasic strain. The analysis of the interaction of enrofloxacin with lavender essential oil was carried out using the checkerboard method. The obtained FICI values were interpreted as follows: synergistic when ≤ 0.5; additive when > 0.5 but ≤ 1; non-interactive when > 1 but ≤ 4; antagonistic when > 4. When analysing individual combinations of enrofloxacin with lavender oil, a positive additive effect was found in all cases (S. Enteritidis ATCC 13076 FICI – 0.85; S. Gallinarum biovar Pullorum ATCC 13036 FICI – 1.0; S. Typhimurium ATCC 14028 and S. Typhimurium – a moderately sensitive monophasic strain FICI – 0.7). Antagonistic interaction was not recorded in any case. When analysing individual combinations of enrofloxacin with lavender oil against the serotypes tested, an additive effect was demonstrated in all cases (FIC indices: 0.7-1.0). There was no antagonistic effect in any of the analysed combinations.
本研究研究了恩诺沙星与薰衣草精油联合使用对3种血清型沙门氏菌的抑菌活性:肠炎沙门氏菌ATCC 13076、鸡产沙门氏菌ATCC 13036、鼠伤寒沙门菌ATCC 14028和鼠伤寒沙门菌-一种中等敏感的单菌种。采用棋盘格法对恩诺沙星与薰衣草精油的相互作用进行了分析。得到的FICI值解释如下:≤0.5时具有协同效应;> 0.5但≤1时可加;当> 1但≤4时不相互作用;bbbb4时拮抗。当分析恩诺沙星与薰衣草油的个别组合时，发现所有病例都有正的加性效应(肠炎沙门氏菌ATCC 13076 FICI - 0.85;Gallinarum biovar Pullorum ATCC 13036 FICI - 1.0;鼠伤寒沙门氏菌ATCC 14028和鼠伤寒沙门氏菌-一种中等敏感的单相菌株FICI - 0.7)。在任何情况下均未记录拮抗相互作用。当分析恩诺沙星与薰衣草油的个别组合对所测试的血清型时，在所有病例中都证明了加性效应(FIC指数:0.7-1.0)。所分析的任何组合均无拮抗作用。
{"title":"In vitro antibacterial effect of enrofloxacin combined with lavender essential oil on selected Salmonella serotypes isolated most commonly poultry","authors":"M. Adaszyńska-Skwirzyńska, S. Zych, D. Szczerbińska","doi":"10.21521/mw.6749","DOIUrl":"https://doi.org/10.21521/mw.6749","url":null,"abstract":"The present study investigated the antimicrobial activity of enrofloxacin in combination with lavender (Lavandula angustifolia) essential oil against three serotypes of Salmonella: Salmonella Enteritidis ATCC 13076, Salmonella Gallinarum biovar Pullorum ATCC 13036, Salmonella Typhimurium ATCC 14028 and Salmonella Typhimurium – a moderately sensitive monophasic strain. The analysis of the interaction of enrofloxacin with lavender essential oil was carried out using the checkerboard method. The obtained FICI values were interpreted as follows: synergistic when ≤ 0.5; additive when > 0.5 but ≤ 1; non-interactive when > 1 but ≤ 4; antagonistic when > 4. When analysing individual combinations of enrofloxacin with lavender oil, a positive additive effect was found in all cases (S. Enteritidis ATCC 13076 FICI – 0.85; S. Gallinarum biovar Pullorum ATCC 13036 FICI – 1.0; S. Typhimurium ATCC 14028 and S. Typhimurium – a moderately sensitive monophasic strain FICI – 0.7). Antagonistic interaction was not recorded in any case. When analysing individual combinations of enrofloxacin with lavender oil against the serotypes tested, an additive effect was demonstrated in all cases (FIC indices: 0.7-1.0). There was no antagonistic effect in any of the analysed combinations.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68104174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Taciak, Maciej Białasek, Karol Pawłowski, E. Hellmén, Emilia Górka, M. Król
Interactions between various cell types in a tumor microenvironment (TME) are important for cancer progression and metastasis. Tumor-associated macrophages (TAMs) play a key role in this intratumoral dialogue regulating Wnt signaling pathway in cancer cells. Co-culture of canine and murine tumor cells with TAMs lead to inhibition of the canonical Wnt pathway and activation of the non-canonical Wnt pathway in tumor cells resulting in change in tumor cell phenotype and subsequent higher potential to invasion and metastasis. These molecular changes in cancer cells that are induced by TAMs resemble the quercetin activity. This natural product is a plant flavonoid from the group of polyphenols. Its biological function is inhibition of the canonical Wnt pathway. As quercetin supplementation is broadly discussed in cancer patients, findings of this study show that this compound should be used with caution, as it may enhance cancer spread.
{"title":"Macrophage regulation of Wnt pathway in canine and murine mammary cancer cells","authors":"B. Taciak, Maciej Białasek, Karol Pawłowski, E. Hellmén, Emilia Górka, M. Król","doi":"10.21521/mw.6757","DOIUrl":"https://doi.org/10.21521/mw.6757","url":null,"abstract":"Interactions between various cell types in a tumor microenvironment (TME) are important for cancer progression and metastasis. Tumor-associated macrophages (TAMs) play a key role in this intratumoral dialogue regulating Wnt signaling pathway in cancer cells. Co-culture of canine and murine tumor cells with TAMs lead to inhibition of the canonical Wnt pathway and activation of the non-canonical Wnt pathway in tumor cells resulting in change in tumor cell phenotype and subsequent higher potential to invasion and metastasis. These molecular changes in cancer cells that are induced by TAMs resemble the quercetin activity. This natural product is a plant flavonoid from the group of polyphenols. Its biological function is inhibition of the canonical Wnt pathway. As quercetin supplementation is broadly discussed in cancer patients, findings of this study show that this compound should be used with caution, as it may enhance cancer spread.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68105458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 3-year-old Leonberger was presented with unilateral atrophy of the left temporal muscle, concomitant left corneal hypoesthesia and jaw pain. Based on magnetic resonance imaging (MRI) results, a trigeminal peripheral nerve sheath tumor was presumptively diagnosed, and treatment based on volumetric modulated arc therapy combined with temozolomide was introduced. Although the tumor volume was stable, after 6 months the patient developed severe jaw pain manifested by rubbing of the face, aversion to eating, and yawning. No desirable response to combinations of meloxicam, gabapentin, tramadol/buprenorphine at their maximal tolerated doses was achieved. Only a treatment based on a commercially available nonpsychoactive cannabinoid oil – Perognidol® (Ilovet) combined with gabapentin successfully relieved the symptoms of pain within a week. Three months later, a follow-up MRI revealed a significant growth of the tumor associated with cerebral infiltration. Eventually, the general condition of the patient deteriorated. The dog was euthanized 800 days after the original diagnosis.
{"title":"Cannabinoid oilwith gabapentin for the treatment of chronicneuropathic pain– case report","authors":"Magdalena E. Wysmołek, Filip Pankowski, U. Latek","doi":"10.21521/mw.6755","DOIUrl":"https://doi.org/10.21521/mw.6755","url":null,"abstract":"A 3-year-old Leonberger was presented with unilateral atrophy of the left temporal muscle, concomitant left corneal hypoesthesia and jaw pain. Based on magnetic resonance imaging (MRI) results, a trigeminal peripheral nerve sheath tumor was presumptively diagnosed, and treatment based on volumetric modulated arc therapy combined with temozolomide was introduced. Although the tumor volume was stable, after 6 months the patient developed severe jaw pain manifested by rubbing of the face, aversion to eating, and yawning. No desirable response to combinations of meloxicam, gabapentin, tramadol/buprenorphine at their maximal tolerated doses was achieved. Only a treatment based on a commercially available nonpsychoactive cannabinoid oil – Perognidol® (Ilovet) combined with gabapentin successfully relieved the symptoms of pain within a week. Three months later, a follow-up MRI revealed a significant growth of the tumor associated with cerebral infiltration. Eventually, the general condition of the patient deteriorated. The dog was euthanized 800 days after the original diagnosis.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68105238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zofia Nowek, M. Mickiewicz, Kinga Biernacka, Agata MOROZ- Fik, O. Szaluś-Jordanow, M. Czopowicz, I. Markowska-Daniel, E. Bagnicka, J. Kaba
A normal thyroid gland is difficult to distinguish from the surrounding tissues. Its enlargement, referred to as goiter, is most often found in newborn kids, less often in adult animals. Feeding errors, such as incorrect iodine content in the ration or the presence of goitrogens, may contribute to its formation. The occurrence of goiter may also have a genetic basis. Mutation within the TG gene leads to abnormal synthesis of thyroglobulin – a protein essential in the synthesis and storage of thyroid hormones. In Poland, the most common problem is congenital goitre, with a genetic background, caused by an increase in inbreeding in the herd.
{"title":"Przyczyny powstawania wola u kóz","authors":"Zofia Nowek, M. Mickiewicz, Kinga Biernacka, Agata MOROZ- Fik, O. Szaluś-Jordanow, M. Czopowicz, I. Markowska-Daniel, E. Bagnicka, J. Kaba","doi":"10.21521/mw.6776","DOIUrl":"https://doi.org/10.21521/mw.6776","url":null,"abstract":"A normal thyroid gland is difficult to distinguish from the surrounding tissues. Its enlargement, referred to as goiter, is most often found in newborn kids, less often in adult animals. Feeding errors, such as incorrect iodine content in the ration or the presence of goitrogens, may contribute to its formation. The occurrence of goiter may also have a genetic basis. Mutation within the TG gene leads to abnormal synthesis of thyroglobulin – a protein essential in the synthesis and storage of thyroid hormones. In Poland, the most common problem is congenital goitre, with a genetic background, caused by an increase in inbreeding in the herd.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68106650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Kaya, H. Özkan, M. Yazlık, B. Camdeviren, Güven Güngör, I. Karaaslan, S. Dalkiran, Hasan Hüseyin Keçeli̇, A. Akçay, A. Yakan
e aim of this study was to evaluate the composition and quality parameters of Simmental and Holstein cows’ milk with different lactation stages under the same environmental conditions. Multiparous Holstein and Simmental cows from different lactation stages (n = 210) were included in the present study. MDA, SCC, composition, and fatty acid analyzes were performed from the collected milk samples. To determine the effect of breed, lactation stage and their interactions, linear mixed models were applied to these parameters. Among the breeds, only milk fat and pH were determined statistically significant as composition parameters. While C15:0 and C17:1 n8 were observed to be statistically significant for the breed factor, C18:2 n6 trans were statistically significant only for the lactation stage factor. Moreover, the fatty acids of C4:0, C6:0, C8:0, C10:0, C11:0, C12:0, C13:0, C16:0, C18:1 n9, C20:0 and C22:6 n3 were determined to be statistically significant in terms of interactions. For the fatty acid indices, SCFA, MCFA, n3 and n6/n3 were statistically significant in terms of interactions while SFA, MUFA, UFA and AI were statistically significant in terms of breeds. On the other hand, new studies are needed to investigate the differences between these breeds at the molecular level for milk quality and fatty acid synthesis.
{"title":"Comparative evaluation of major milk quality parameters of Holstein and Simmental cows at different lactation stages under similar environmental conditions","authors":"U. Kaya, H. Özkan, M. Yazlık, B. Camdeviren, Güven Güngör, I. Karaaslan, S. Dalkiran, Hasan Hüseyin Keçeli̇, A. Akçay, A. Yakan","doi":"10.21521/mw.6779","DOIUrl":"https://doi.org/10.21521/mw.6779","url":null,"abstract":"e aim of this study was to evaluate the composition and quality parameters of Simmental and Holstein cows’ milk with different lactation stages under the same environmental conditions. Multiparous Holstein and Simmental cows from different lactation stages (n = 210) were included in the present study. MDA, SCC, composition, and fatty acid analyzes were performed from the collected milk samples. To determine the effect of breed, lactation stage and their interactions, linear mixed models were applied to these parameters. Among the breeds, only milk fat and pH were determined statistically significant as composition parameters. While C15:0 and C17:1 n8 were observed to be statistically significant for the breed factor, C18:2 n6 trans were statistically significant only for the lactation stage factor. Moreover, the fatty acids of C4:0, C6:0, C8:0, C10:0, C11:0, C12:0, C13:0, C16:0, C18:1 n9, C20:0 and C22:6 n3 were determined to be statistically significant in terms of interactions. For the fatty acid indices, SCFA, MCFA, n3 and n6/n3 were statistically significant in terms of interactions while SFA, MUFA, UFA and AI were statistically significant in terms of breeds. On the other hand, new studies are needed to investigate the differences between these breeds at the molecular level for milk quality and fatty acid synthesis.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68107496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Foot-and-mouth disease (FMD) and bluetongue disease (BT) are two of the most devastating viral diseases affecting domestic and wild ruminants. They cause significant economic losses, and vaccination is the most important method for combating both FMD and BT. Simultaneous vaccinations are crucial for animal welfare as well as labor and cost savings. No reports were found on the simultaneous administration of FMD and BT vaccines to sheep. This study evaluated the effect of the simultaneous administration of an inactivated FMD vaccine and an attenuated BT vaccine on the humoral immune response to both diseases. A total of 75 sixmonth- old Akkaraman-Kıvırcık crossbred sheep that did not have any vaccination history were used as research material. Before the experiment, the animals were tested for the absence of FMD and BT antibodies. The sheep were divided into three experimental groups and vaccinated with an FMD vaccine alone, a BT vaccine alone, and both. Blood samples were taken on days 30 and 60 post-vaccination. The blood samples were evaluated using liquid-phase blocking ELISA (LPBE) and virus neutralization test (VNT) for FMD antibodies, as well as competitive ELISA (c-ELISA) and VNT for BT antibodies. The study revealed that differences between the FMD and BT antibody titers of the group vaccinated simultaneously and the FMD and BT antibody titers obtained from the groups vaccinated separately were not statistically significant (p > 0.05). It was concluded that the antibody response these diseases was not altered when the FMD and BT vaccines were administered together.
{"title":"Ultrasound monitoring of the regenerative treatment of Biceps Tendonitis and Tenosynovitis in dogs by stem cells injections","authors":"Sevil Sardoğan, O. Bulut, V. Gülyaz","doi":"10.21521/mw.6814","DOIUrl":"https://doi.org/10.21521/mw.6814","url":null,"abstract":"Foot-and-mouth disease (FMD) and bluetongue disease (BT) are two of the most devastating viral diseases affecting domestic and wild ruminants. They cause significant economic losses, and vaccination is the most important method for combating both FMD and BT. Simultaneous vaccinations are crucial for animal welfare as well as labor and cost savings. No reports were found on the simultaneous administration of FMD and BT vaccines to sheep. This study evaluated the effect of the simultaneous administration of an inactivated FMD vaccine and an attenuated BT vaccine on the humoral immune response to both diseases. A total of 75 sixmonth- old Akkaraman-Kıvırcık crossbred sheep that did not have any vaccination history were used as research material. Before the experiment, the animals were tested for the absence of FMD and BT antibodies. The sheep were divided into three experimental groups and vaccinated with an FMD vaccine alone, a BT vaccine alone, and both. Blood samples were taken on days 30 and 60 post-vaccination. The blood samples were evaluated using liquid-phase blocking ELISA (LPBE) and virus neutralization test (VNT) for FMD antibodies, as well as competitive ELISA (c-ELISA) and VNT for BT antibodies. The study revealed that differences between the FMD and BT antibody titers of the group vaccinated simultaneously and the FMD and BT antibody titers obtained from the groups vaccinated separately were not statistically significant (p > 0.05). It was concluded that the antibody response these diseases was not altered when the FMD and BT vaccines were administered together.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68109745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tarsocrural arthrodesis was performed in a cat using Kirschner pins in the crosspinning technique with an additional tension band. Short term radiological and clinical outcomes, arthrodesis progression were assessed. 10 weeks after surgery the clinical examination showed no lameness and the patient’s condition was described as „very good”, radiographically there was a new callus formation bridging the tarsocrural joint with bone remodeling. The functional score was favorable indicating very good postoperative outcomes in terms of the possibility of the cat to perform normal feline activities with no pain.
{"title":"Tarsocrural arthrodesis using K-wires and crosspinning technique in a cat: a case report","authors":"MAGDALENA MORAWSKA-KOZŁOWSKA, YAUHENI ZHALNIAROVICH","doi":"10.21521/mw.6819","DOIUrl":"https://doi.org/10.21521/mw.6819","url":null,"abstract":"Tarsocrural arthrodesis was performed in a cat using Kirschner pins in the crosspinning technique with an additional tension band. Short term radiological and clinical outcomes, arthrodesis progression were assessed. 10 weeks after surgery the clinical examination showed no lameness and the patient’s condition was described as „very good”, radiographically there was a new callus formation bridging the tarsocrural joint with bone remodeling. The functional score was favorable indicating very good postoperative outcomes in terms of the possibility of the cat to perform normal feline activities with no pain.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135440807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paweł Górski, Ewa Długosz, J. Bartosik, P. Bąska, J. Łojek, W. Zygner, J. Karabowicz, M. Wiśniewski
The aim of the study was to morphologically and genetically compare parasitic nematodes from the genus Uncinaria found in different hosts. These common parasites belong to hookworm nematodes (family Ancylostomatidae). Worms were collected during dissection of mammals obtained from the Institute of Veterinary Hygiene in Warsaw, where the animals had been tested for rabies. The hosts of the nematodes were European badgers (Meles meles) from the family Mustelidae, as well as red foxes (Vulpes vulpes), dogs (Canis familiaris), and raccoon dogs (Nyctereutes procyonoides) from the family Canidae. The parasites were viewed under a microscope, and identified on the basis of their morphological features characteristic of the species U. stenocephala. Isolated, PCR-amplified, and sequenced rDNA segments containing internal transcribed spacer segments (ITS1 and ITS2) in the gene encoding 5.8S rDNA were also compared. No genetic or morphological differences were found between Uncinaria hookworms obtained from the four different host species. This means that wild raccoon dogs and badgers can be a source and reservoir for the hookworm U. stenocephala that infects dogs.
{"title":"Morphological and molecular comparison of nematodes from the family Ancylostomatidae isolated from selected species of carnivorous mammals in central Poland","authors":"Paweł Górski, Ewa Długosz, J. Bartosik, P. Bąska, J. Łojek, W. Zygner, J. Karabowicz, M. Wiśniewski","doi":"10.21521/mw.6766","DOIUrl":"https://doi.org/10.21521/mw.6766","url":null,"abstract":"The aim of the study was to morphologically and genetically compare parasitic nematodes from the genus Uncinaria found in different hosts. These common parasites belong to hookworm nematodes (family Ancylostomatidae). Worms were collected during dissection of mammals obtained from the Institute of Veterinary Hygiene in Warsaw, where the animals had been tested for rabies. The hosts of the nematodes were European badgers (Meles meles) from the family Mustelidae, as well as red foxes (Vulpes vulpes), dogs (Canis familiaris), and raccoon dogs (Nyctereutes procyonoides) from the family Canidae. The parasites were viewed under a microscope, and identified on the basis of their morphological features characteristic of the species U. stenocephala. Isolated, PCR-amplified, and sequenced rDNA segments containing internal transcribed spacer segments (ITS1 and ITS2) in the gene encoding 5.8S rDNA were also compared. No genetic or morphological differences were found between Uncinaria hookworms obtained from the four different host species. This means that wild raccoon dogs and badgers can be a source and reservoir for the hookworm U. stenocephala that infects dogs.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68105472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Mordak, Z. Dobrzański, J. Popiel, R. Kupczyński
The aim of the study was to assess the values of and correlations between selected markers of acid-base balance and electrolytes in the blood of late lactation cows, such as pH, pCO2, pO2, HCO3 –, BE, BE(B), Na+, K+, Cl–, as well as selected parameters of milk, such as the number of somatic cells (SCC), colony forming units (CFU), milk fat (MF), milk protein (MP), milk lactose (ML), milk solids, milk solids non-fat (SNF), and current milk production. Blood and milk samples were collected at the same time from 11 clinically healthy milking cows in the later lactation period. Those 11 selected cows were examined once a day for 3 consecutive days resulting in 33 sets of blood and milk samples used for laboratory and statistical analyses. Significant positive correlations were observed between pH and HCO3 –, pH and BE, pH and BE(B), pCO2 and HCO3 –, pCO2 and BE, pCO2 and BE(B), HCO3 – and BE, HCO3 – and BE(B), BE and BE(B), Na+ and Cl–, Na+ and milk production, Cl– and milk production, and Cl– and MP. Significant negative correlations were observed between pH and K+, pH and Cl–, pCO2 and Cl–, HCO3 – and Cl–, BE and Cl–, and BE(B) and Cl–. The increase in blood pH was significantly negatively correlated with the current milk production, while the increase in HCO3 – or pCO2 was associated with a significant decrease in the amount of protein in milk. These relations can indicate a significant negative influence of blood acid-base imbalance on the quantity and quality of cow’s milk. The repeatable diagnostic model presented here proved to be a very useful tool for a detailed assessment of selected higly sensitive parameters of internal homeostasis in productive dairy cows.
{"title":"Analysis of Correlations between Selected Blood Markers of Acid-Base Balance, Blood Electrolytes, and Milk Components in Dairy Cows during Late Lactation","authors":"R. Mordak, Z. Dobrzański, J. Popiel, R. Kupczyński","doi":"10.21521/mw.6787","DOIUrl":"https://doi.org/10.21521/mw.6787","url":null,"abstract":"The aim of the study was to assess the values of and correlations between selected markers of acid-base balance and electrolytes in the blood of late lactation cows, such as pH, pCO2, pO2, HCO3 –, BE, BE(B), Na+, K+, Cl–, as well as selected parameters of milk, such as the number of somatic cells (SCC), colony forming units (CFU), milk fat (MF), milk protein (MP), milk lactose (ML), milk solids, milk solids non-fat (SNF), and current milk production. Blood and milk samples were collected at the same time from 11 clinically healthy milking cows in the later lactation period. Those 11 selected cows were examined once a day for 3 consecutive days resulting in 33 sets of blood and milk samples used for laboratory and statistical analyses. Significant positive correlations were observed between pH and HCO3 –, pH and BE, pH and BE(B), pCO2 and HCO3 –, pCO2 and BE, pCO2 and BE(B), HCO3 – and BE, HCO3 – and BE(B), BE and BE(B), Na+ and Cl–, Na+ and milk production, Cl– and milk production, and Cl– and MP. Significant negative correlations were observed between pH and K+, pH and Cl–, pCO2 and Cl–, HCO3 – and Cl–, BE and Cl–, and BE(B) and Cl–. The increase in blood pH was significantly negatively correlated with the current milk production, while the increase in HCO3 – or pCO2 was associated with a significant decrease in the amount of protein in milk. These relations can indicate a significant negative influence of blood acid-base imbalance on the quantity and quality of cow’s milk. The repeatable diagnostic model presented here proved to be a very useful tool for a detailed assessment of selected higly sensitive parameters of internal homeostasis in productive dairy cows.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68107857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging is a major risk factor for cognitive decline, such as Alzheimer’s disease (AD). Sheep’s milk may play a role in the prevention of neurodegenerative diseases because of its high content of functional peptides, such as lactoferrin. Lactoferrin can be used in AD both as an active therapeutic compound and as a drug nanocarrier. Compared to cow’s and goat’s milks, sheep’s milk contains the highest content of isomers of conjugated linoleic acid (CLA). The c-9, t-11-CLA isomers reduce the pathological changes occurring in AD mainly by reducing the amount of amyloid-β aggregates in brain tissues. Sheep’s milk also contains higher concentrations of vitamin D and B-group vitamins, which have neuroprotective effects. This review summarizes the current knowledge on sheep’s milk and its products, with a special focus on its role in the prevention of neurodegenerative diseases.
{"title":"Role of bioactive substances in sheep's milk and its products in the prevention of neurodegenerative diseases","authors":"Zuzanna Flis, E. Molik","doi":"10.21521/mw.6796","DOIUrl":"https://doi.org/10.21521/mw.6796","url":null,"abstract":"Aging is a major risk factor for cognitive decline, such as Alzheimer’s disease (AD). Sheep’s milk may play a role in the prevention of neurodegenerative diseases because of its high content of functional peptides, such as lactoferrin. Lactoferrin can be used in AD both as an active therapeutic compound and as a drug nanocarrier. Compared to cow’s and goat’s milks, sheep’s milk contains the highest content of isomers of conjugated linoleic acid (CLA). The c-9, t-11-CLA isomers reduce the pathological changes occurring in AD mainly by reducing the amount of amyloid-β aggregates in brain tissues. Sheep’s milk also contains higher concentrations of vitamin D and B-group vitamins, which have neuroprotective effects. This review summarizes the current knowledge on sheep’s milk and its products, with a special focus on its role in the prevention of neurodegenerative diseases.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68108513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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