Contact Lens & Anterior Eye最新文献_第9页

Is there a difference in fitting time for spherical and toric soft contact lenses? 球形和圆环软性隐形眼镜的配戴时间有区别吗？

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-11-01 DOI: 10.1016/j.clae.2025.102528

Anna Sulley , Rachel Marullo , Michel Guillon , Pasquale Pepe , Percy Lazon De La Jara

引用次数: 0

Influence of pupil size on vision performance and visual satisfaction with two multifocal contact lenses 瞳孔大小对双焦隐形眼镜视力表现和视觉满意度的影响

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-11-01 DOI: 10.1016/j.clae.2025.102560

Percy Lazon de la Jara , Anna Sulley , Rachel Marullo , MIchel Guillon

引用次数: 0

Examination of soft contact lens condition versus subjective symptoms following one month’s wear 软性隐形眼镜佩戴一个月后的主观症状与状态的对比

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-11-01 DOI: 10.1016/j.clae.2025.102548

Neema Ghorbani Mojarrad , Lindsay Rountree , Thomas Swift , Antony Scimone

引用次数: 0

In vitro antibacterial efficacy and antibiofilm activity on contact lenses of a new ophthalmic spray containing Biosecur® citrus extract (Oftasecur®) 一种含有biosecure®柑橘提取物（Oftasecur®）的新型眼科喷雾剂对隐形眼镜的体外抗菌效果和抗生物膜活性。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-27 DOI: 10.1016/j.clae.2025.102521

Antonio Pinna , Thomas P. Thompson , Matthew G. Donadu , Matteo Sacchi , Rita Serra , Mario Fruschelli , Brendan F. Gilmore , Stefano Dore

Purpose

To investigate the in vitro antimicrobial activity of a new commercial ocular spray containing 0.2% Biosecur® citrus extract (Oftasecur®) against Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli and test its efficacy in preventing biofilm formation on etafilcon A and senofilcon A contact lenses.

Methods

Antibacterial activity against Staphylococcus epidermidis ATCC 12228, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa PAO1, and Escherichia coli NCTC 10418 was evaluated by microdilution in Mueller–Hinton broth (MHB). Inocula were standardised to OD600 and MIC/MBC determined across a 50 % to 0.195 % (v/v) dilution range of Oftasecur®. Early biofilm formation on etafilcon A and senofilcon A lenses was assessed over 24 h using alamarBlue™ at 10 % (v/v) with fluorescence recorded (Ex 584 nm, Em 590 nm) every 30 min. Lenses were rinsed in sterile phosphate-buffered saline (PBS; 3 × 5 mL) before use. Data were analysed by assumption-checked parametric/non-parametric tests (one-way ANOVA with Tukey or Kruskal–Wallis with Dunn; α = 0.05).

Results

Across species, the MIC was 50 % (v/v) and MBC exceeded 50 % (v/v). On both lens materials, Oftasecur® significantly reduced alamarBlue-measured metabolic activity during early lens–bacteria interactions relative to untreated controls over 24 h (p < 0.05), consistent with inhibition of early biofilm-associated growth. Reductions were observed for all species, with the largest effects for Gram-negative strains.

Conclusions

Oftasecur® demonstrated concentration-dependent antibacterial activity against reference ocular pathogens and suppressed early biofilm-associated metabolism on common contact lens materials. These findings support further ex vivo and clinical studies to determine whether Oftasecur® can help prevent contact lens–related bacterial keratitis.

目的：研究含0.2% Biosecur®柑橘提取物（Oftasecur®）的新型商品化眼喷液对表皮葡萄球菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌的体外抑菌活性，并检测其对埃他非康a和senofilcon a隐形眼镜生物膜形成的抑制作用。方法：采用微量稀释法对表皮葡萄球菌ATCC 12228、金黄色葡萄球菌ATCC 25923、铜绿假单胞菌PAO1、大肠埃希菌NCTC 10418进行抑菌活性测定。将接种物标准化至OD600，并在Oftasecur®稀释50%至0.195% （v/v）范围内测定MIC/MBC。使用10% （v/v）的alamarBlue™评估etafilcon A和senofilcon A镜片上的早期生物膜形成情况，持续24小时，每30分钟记录一次荧光（Ex 584 nm, Em 590 nm）。镜片使用前用无菌磷酸盐缓冲盐水（PBS; 3 × 5 mL）冲洗。数据分析采用假设检验的参数/非参数检验（单因素方差分析与Tukey或Kruskal-Wallis与Dunn； α = 0.05）。结果：不同种属间MIC值为50% (v/v)， MBC值超过50% （v/v）。在这两种隐形眼镜材料上，相对于未处理的对照组，Oftasecur®在24小时内显著降低了alamarblue测量的早期隐形眼镜细菌相互作用中的代谢活性(p)。结论：Oftasecur®对参考眼部病原体具有浓度依赖性的抗菌活性，并抑制了普通隐形眼镜材料上早期生物膜相关的代谢。这些发现支持进一步的离体和临床研究，以确定Oftasecur®是否有助于预防与隐形眼镜相关的细菌性角膜炎。

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引用次数: 0

A survey of contact lens users: Adherence to care guidelines and knowledge of microbial keratitis risk 对隐形眼镜使用者的调查：遵守护理指南和了解微生物角膜炎风险。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-22 DOI: 10.1016/j.clae.2025.102516

Eman AlBalawi , Rawan Bin Salamah , Reem Altamimi , Reem AlSarhan , Jana Alyousef

Background

Contact lenses are widely used for cosmetic and refractive purposes. Proper usage and hygiene are critical to preventing ocular complications like microbial keratitis (MK). This study aims to assess the level of awareness and practices regarding contact lens use and hygiene among a sample population.

Methodology

A cross-sectional survey was conducted among 434 contact lens users. Data on demographic factors, reasons for contact lens use, duration and frequency of use, types of lenses, hygiene practices, and awareness of MK were collected and analyzed. Statistical associations between awareness, practices, and various demographic and usage factors were examined using chi-square tests.

Results

Most participants were 18–25 years old (248, 57.1 %) and female (393, 90.6 %). The primary reason for contact lens use was cosmetic (216, 49.8 %), followed by refractive purposes (116, 27.4 %). Most participants used soft regular contact lenses (385, 88.7 %) for 5–8 h daily (248, 57.1 %) and had been using them for 1–5 years (163, 37.6 %). Confidence in contact lens care knowledge was high, with (120, 27.6 %) being “Extremely confident.” A significant portion (319, 73.5 %) had adequate awareness of MK, with females exhibiting higher awareness levels than males (p = 0.000). Good hygiene practices were reported by (425, 97.9 %) of participants, though gaps in specific practices like rubbing lenses during cleaning (243, 56.0 %) were noted. There was a significant association between high confidence in lens care knowledge and adequate awareness of MK (p = 0.005).

Conclusion

The study highlights good hygiene practices among contact lens users, though awareness of MK varies. Female users and those with higher confidence in lens care knowledge showed better awareness and practices. Targeted educational initiatives can further enhance awareness and proper practices to prevent MK and other complications associated with contact lens use.

背景：隐形眼镜被广泛用于美容和屈光目的。正确使用和卫生对于预防微生物性角膜炎等眼部并发症至关重要。本研究旨在评估样本人群对隐形眼镜使用和卫生的认识和实践水平。方法：对434名隐形眼镜使用者进行横断面调查。收集和分析人口统计学因素、使用隐形眼镜的原因、使用时间和频率、隐形眼镜类型、卫生习惯和MK意识等方面的数据。使用卡方检验检验了意识、实践和各种人口统计学和使用因素之间的统计关联。结果：以18-25岁的248人（57.1%）和女性393人（90.6%）为主。使用隐形眼镜的主要原因是美容（216例，49.8%），其次是屈光目的（116例，27.4%）。大多数参与者每天使用软质普通隐形眼镜5-8小时（385人，88.7%），使用时间为1-5年（163人，37.6%）。对隐形眼镜护理知识的信心很高，（120.27.6%）表示“非常有信心”。相当一部分人（319,73.5%）对MK有足够的认识，女性的认识水平高于男性（p = 0.000）。（425人，97.9%）的参与者报告了良好的卫生习惯，尽管注意到在清洁过程中摩擦镜片等具体做法存在差距（243人，56.0%）。对晶状体护理知识的高度自信与足够的MK意识之间存在显著关联（p = 0.005）。结论：该研究强调了隐形眼镜使用者的良好卫生习惯，尽管对MK的认识各不相同。女性用户和对镜片护理知识信心较高的用户表现出更好的意识和实践。有针对性的教育举措可以进一步提高认识和正确做法，以防止MK和其他与使用隐形眼镜有关的并发症。

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引用次数: 0

Contact lens discomfort and associated conditions: Definitions and disambiguation relative to dry eye disease 隐形眼镜不适和相关条件：干眼症的定义和消除歧义。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-21 DOI: 10.1016/j.clae.2025.102520

Eric B. Papas

Terminology used in relation to contact lens discomfort, and its associated conditions has proliferated, leading to confusion and misuse. This short article demonstrates that the lexicon can be reduced to four terms, which are sufficient to describe the field. These are contact lens discomfort (CLD), contact lens associated dry eye (CLADE), contact lens induced dry eye (CLIDE) and dry eye disease (DED). Definitions for these conditions are clarified and their diagnostic pathways described. Exclusive use of these defined terms is recommended to avoid future misunderstanding, simplify clinical differential diagnosis, maximise treatment efficacy and facilitate the interpretation of research outputs by promoting characterisation of homogenous study groups.

与隐形眼镜不适及其相关条件相关的术语已经激增，导致混淆和误用。这篇短文演示了该词典可以简化为四个术语，这足以描述该领域。它们分别是隐形眼镜不适（CLD）、隐形眼镜相关性干眼（CLADE）、隐形眼镜诱发性干眼（CLIDE）和干眼病（DED）。澄清了这些条件的定义并描述了其诊断途径。建议专门使用这些已定义的术语，以避免未来的误解，简化临床鉴别诊断，最大限度地提高治疗效果，并通过促进同质研究组的特征来促进对研究成果的解释。

引用次数: 0

Standardized evaluation of orthokeratology lens fitting status assisted by deep learning algorithm 深度学习算法辅助角膜塑形镜配镜状态的标准化评价。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-19 DOI: 10.1016/j.clae.2025.102519

Wenting Song , Yong Zhang , Chuan Wan , Ming Liu , Shuai Wang , Hang Yin , Min Xue , Hongbiao Pan , Lei Shi

Objective

Aims to develop a standardized evaluation method based on the YOLOv8n object detection algorithm, with the goal of quantitatively assessing the displacement of orthokeratology lenses (OK_lenses) and objectively evaluating their fitting status under fluorescein staining conditions.

Methods

117 videos documenting of the fluorescein sodium staining fitting process of OK_lenses, were analyzed alongside corresponding ophthalmic examination results. Key frames were extracted from these videos, annotated, and compiled into a local dataset. A YOLOv8n object detection algorithm model was constructed to automatically identify the visible iris and OK_lenses. The lens displacement was calculated based on the distance between the center points of these two targets and the horizontal visible iris diameter (HVID). Model performance was evaluated using Accuracy, Recall, and F1-score metrics, while consistency was assessed via the Kappa consistency test and compared with traditional manual assessment results.

Results

Achieved automatic calculation of OK_lens displacement in fluorescein-stained images and analysis of their fitting status through the application of the YOLOv8n object detection algorithm. For iris and lens detection, the model yielded accuracy, recall, and F1-score values of 97.6 %, 98.8 %, 98.2 % and 98.4 %, 98.9 %, 98.6 %, respectively. In terms of fitting status assessment, the accuracy of the three prediction results of this model compared with the gold standard was 88.6 %, 91.4 % and 88.6 % respectively, the average accuracy rate was 89.5 %, and all Kappa values were > 0.80, showing a high consistency with the gold standard.

Conclusion

The YOLOv8n object detection algorithm model demonstrates strong concordance with the gold standard and high accuracy, validating its robust replication of the gold standard’s evaluation logic. By enabling the objective, quantitative analysis of lens displacement in fluorescein-stained images, this highly stable and objective model could serve as a standardized tool to complement traditional manual evaluations. It offers considerable value for improving assessment efficiency of physicians lacking fitting experience and reducing subjective bias during fitting procedures. Notably, this study may not improve efficiency for experienced fitting physicians, as the steps and time required for fitting may not be significantly reduced. To further verify its generalization ability, future studies should expand the sample size and incorporate multi-center data for comprehensive validation to support its transition toward clinical standardization.

目的：建立一种基于YOLOv8n目标检测算法的标准化评价方法，定量评价角膜塑形镜（OK_lenses）在荧光素染色条件下的位移情况，客观评价其拟合状态。方法：对117段记录ok_lens荧光素钠染色配体过程的视频资料进行分析，并结合相应的眼科检查结果。从这些视频中提取关键帧，进行注释，并编译成本地数据集。构建YOLOv8n目标检测算法模型，自动识别可见虹膜和ok_lens。根据两个目标中心点之间的距离和水平可见光圈直径（HVID）计算透镜位移。模型性能通过准确性、召回率和f1评分指标进行评估，而一致性通过Kappa一致性测试进行评估，并与传统的人工评估结果进行比较。结果：通过应用YOLOv8n目标检测算法，实现了荧光染色图像中OK_lens位移的自动计算和拟合状态分析。对于虹膜和晶状体检测，该模型的准确率、召回率和f1评分分别为97.6%、98.8%、98.2%和98.4%、98.9%、98.6%。在拟合状态评价方面，该模型的三种预测结果与金标准的准确率分别为88.6%、91.4%和88.6%，平均准确率为89.5%，Kappa值均为>.80，与金标准的一致性较高。结论：YOLOv8n目标检测算法模型与金标准一致性强，准确率高，验证了其对金标准评价逻辑的鲁棒性复制。通过对荧光素染色图像中晶状体位移的客观定量分析，这种高度稳定和客观的模型可以作为一种标准化工具来补充传统的人工评估。对于提高缺乏拟合经验的医师的评估效率，减少拟合过程中的主观偏差具有相当的价值。值得注意的是，本研究可能不会提高经验丰富的拟合医生的效率，因为拟合所需的步骤和时间可能不会显着减少。为了进一步验证其泛化能力，未来的研究应扩大样本量，纳入多中心数据进行综合验证，以支持其向临床标准化过渡。

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引用次数: 0

The relationship between relative peripheral refraction and axial length elongation in myopic children wearing orthokeratology lenses using a novel wide-angle multispectral refraction topographer 应用新型广角多光谱屈光度地形仪研究近视儿童角膜塑形镜的相对外周屈光度与眼轴长度伸长的关系。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-13 DOI: 10.1016/j.clae.2025.102517

Mandantuoya, Mingxin Ao, Yu Zhang

Purpose

To investigate the peripheral retinal relative defocus in myopic children wearing orthokeratology (OK) lenses and evaluate its relationship with the efficacy of myopia control.

Methods

Wide-angle (150° field of view) relative peripheral refraction and axial length measurements were conducted in 48 children wearing OK lenses. Key peripheral refraction parameters included minimum defocus distance, defocus ring outer diameter, defocus ring inner diameter, defocus ring width, and retinal relative defocus values (RDVs). Pearson correlation analysis was used to evaluate the associations between axial elongation rate and these parameters. Multiple regression analysis was constructed to predict axial elongation, mainly based on the parameters of peripheral retinal defocus.

Results

Peripheral myopic defocus was observed in children wearing OK lenses. Axial elongation rate showed a negative correlation with defocus ring outer diameter (R = −0.388, P < 0.01) and defocus ring width (R = −0.503, P < 0.01), while it was positively correlated with minimum defocus distance (R = 0.383, P < 0.01) and defocus ring inner diameter (R = 0.309, P < 0.01). RDV-53, RDV-45, RDV-(30–45), RDV-(45–53), RDV-N, and RDV-I also showed significant positive correlations with axial elongation rate (P < 0.01). Age, baseline axial length, defocus ring width, minimum defocus distance, and RDV-(45–53) were five predictors in the multivariable prediction model.

Conclusion

Wearing OK lenses induced peripheral myopic defocus. Larger defocus ring width, closer defocus ring to the macular zone and greater relative peripheral myopic defocus were associated with less axial elongation. Peripheral defocus parameters combined with age and baseline axial length could predict axial elongation to some extent.

目的：探讨角膜塑形镜（orthokeratology， OK）配戴后近视儿童周围视网膜相对离焦情况，并评价其与近视控制效果的关系。方法：对48例配戴OK隐形眼镜的儿童进行广角（150°视场）相对外周屈光度和眼轴长度测量。关键外周折射参数包括最小离焦距离、离焦环外径、离焦环内径、离焦环宽度和视网膜相对离焦值（RDVs）。使用Pearson相关分析来评估轴向伸长率与这些参数之间的关系。以视网膜周围离焦参数为主要参数，构建多元回归分析预测轴向伸长。结果：儿童配戴OK隐形眼镜后出现外周性近视离焦。轴向伸长率与离焦环外径（R = -0.388, P < 0.01）和离焦环宽度（R = -0.503, P < 0.01）呈负相关，与最小离焦距离（R = 0.383, P < 0.01）和离焦环内径（R = 0.309, P < 0.01）呈正相关。RDV-53、RDV-45、RDV-(30-45)、RDV-(45-53)、RDV- n和RDV- i与轴向伸长率呈极显著正相关（P < 0.01）。年龄、基线轴长、离焦环宽度、最小离焦距离和RDV-(45-53)是多变量预测模型中的5个预测因子。结论：佩戴OK晶状体可引起周围性近视离焦。离焦环宽度越大、离黄斑区越近、相对外周近视离焦越大，轴向伸长越小。外周离焦参数结合年龄和基线轴长可以在一定程度上预测轴向伸长。

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引用次数: 0

Influence of baseline characteristics on subjective improvement of dry eye after intense pulsed light therapy 基线特征对强脉冲光治疗后干眼主观改善的影响。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-07 DOI: 10.1016/j.clae.2025.102514

Miriam Carrillo-Pulido , Sonia Ortiz-Peregrina , María Dolores López Pérez , Antonio Cano-Ortiz , Timoteo González-Cruces

Purpose

To identify baseline clinical signs and symptoms associated with response to intense pulsed light (IPL) combined with meibomian gland expression in dry eye disease (DED), and to develop machine learning (ML) models for individualized outcome prediction.

Methods

This retrospective study analyzed 100 eyes from 100 DED patients (aged 58.6 ± 13.4 years) treated with IPL and meibomian gland expression. Baseline parameters assessed with the Antares system included meibomian gland loss (MGL), tear meniscus height (TMH), non-invasive tear break-up time (NIBUT), conjunctival hyperemia, and Ocular Surface Disease Index (OSDI). Patients were stratified by change in OSDI after treatment (ΔOSDI): Class 1 (no improvement), Class 2 (mild improvement), and Class 3 (clear improvement). Several ML models were trained to predict ΔOSDI from baseline parameters.

Results

IPL significantly improved both symptoms and signs. OSDI decreased from 44.65 ± 18.3 to 28.47 ± 19.3 (p < 0.001), NIBUT increased from 4.5 ± 3.2 to 7.5 ± 6.5 s (p < 0.001), and TMH and conjunctival hyperemia also improved (p < 0.001), while MGL and BCVA remained stable. Greater improvement was observed in patients with higher baseline OSDI (p = 0.001). The XGBoost algorithm achieved the highest predictive performance (AUC-ROC = 0.77), with OSDI and NIBUT as the strongest predictors based on SHAP analysis.

Conclusions

IPL combined with meibomian gland expression improves symptoms and signs in DED, particularly in patients with more severe baseline symptoms. Baseline OSDI and NIBUT were the strongest predictors of response. ML models demonstrated moderate accuracy, supporting their potential role in personalized DED treatment strategies.

目的：确定干眼病（DED）患者对强脉冲光（IPL）联合睑板腺表达的反应相关的基线临床体征和症状，并建立用于个体化预后预测的机器学习（ML）模型。方法：对100例DED患者（年龄58.6±13.4岁）100只眼进行IPL +睑板腺表达治疗的回顾性研究。使用Antares系统评估的基线参数包括睑板腺损失（MGL）、泪液半月板高度（TMH）、非侵入性泪液破裂时间（NIBUT）、结膜充血和眼表疾病指数（OSDI）。根据治疗后OSDI的变化对患者进行分层（ΔOSDI）： 1级（无改善），2级（轻度改善）和3级（明显改善）。训练几个ML模型来从基线参数预测ΔOSDI。结果：IPL可显著改善患者的症状和体征。OSDI从44.65±18.3降至28.47±19.3 (p)。结论：IPL联合睑板腺表达可改善DED患者的症状和体征，特别是对基线症状较严重的患者。基线OSDI和NIBUT是反应的最强预测因子。ML模型显示出中等的准确性，支持其在个性化DED治疗策略中的潜在作用。

{"title":"Influence of baseline characteristics on subjective improvement of dry eye after intense pulsed light therapy","authors":"Miriam Carrillo-Pulido , Sonia Ortiz-Peregrina , María Dolores López Pérez , Antonio Cano-Ortiz , Timoteo González-Cruces","doi":"10.1016/j.clae.2025.102514","DOIUrl":"10.1016/j.clae.2025.102514","url":null,"abstract":"<div><h3>Purpose</h3><div>To identify baseline clinical signs and symptoms associated with response to intense pulsed light (IPL) combined with meibomian gland expression in dry eye disease (DED), and to develop machine learning (ML) models for individualized outcome prediction.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed 100 eyes from 100 DED patients (aged 58.6 ± 13.4 years) treated with IPL and meibomian gland expression. Baseline parameters assessed with the Antares system included meibomian gland loss (MGL), tear meniscus height (TMH), non-invasive tear break-up time (NIBUT), conjunctival hyperemia, and Ocular Surface Disease Index (OSDI). Patients were stratified by change in OSDI after treatment (ΔOSDI): Class 1 (no improvement), Class 2 (mild improvement), and Class 3 (clear improvement). Several ML models were trained to predict ΔOSDI from baseline parameters.</div></div><div><h3>Results</h3><div>IPL significantly improved both symptoms and signs. OSDI decreased from 44.65 ± 18.3 to 28.47 ± 19.3 (p < 0.001), NIBUT increased from 4.5 ± 3.2 to 7.5 ± 6.5 s (p < 0.001), and TMH and conjunctival hyperemia also improved (p < 0.001), while MGL and BCVA remained stable. Greater improvement was observed in patients with higher baseline OSDI (p = 0.001). The XGBoost algorithm achieved the highest predictive performance (AUC-ROC = 0.77), with OSDI and NIBUT as the strongest predictors based on SHAP analysis.</div></div><div><h3>Conclusions</h3><div>IPL combined with meibomian gland expression improves symptoms and signs in DED, particularly in patients with more severe baseline symptoms. Baseline OSDI and NIBUT were the strongest predictors of response. ML models demonstrated moderate accuracy, supporting their potential role in personalized DED treatment strategies.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 1","pages":"Article 102514"},"PeriodicalIF":3.7,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of ambient illuminance and mobile phone screen brightness on tear film stability, visual fatigue, and blink patterns during reading 环境照度和手机屏幕亮度对阅读时泪膜稳定性、视觉疲劳和眨眼模式的影响。

IF 3.7 3区医学 Q1 OPHTHALMOLOGY

Contact Lens & Anterior Eye

Pub Date : 2025-10-06 DOI: 10.1016/j.clae.2025.102515

Meng Lin , Xinkai Zheng , Charong He , Meng Li , Fan Lu , Liang Hu

Purpose

This study aimed to investigate the impacts of different ambient illuminance and screen brightness conditions on tear film stability, visual fatigue, and blink patterns during mobile phone reading.

Methods

This prospective study involved 30 young subjects who completed 4 experiments based on ambient illuminance and screen brightness: Group 1: bright room, bright screen; Group 2: dark room, dark screen; Group 3: bright room, dark screen; Group 4: dark room, bright screen. Participants completed a 30-minute mobile phone reading task in each experiment. Tear film stability indicators, including fluorescein tear break-up time (FTBUT), noninvasive tear breakup time, tear meniscus height, and lipid layer thickness, were measured before and after reading. During reading, an infrared camera recorded blink-related parameters. Subjective questionnaires assessed comfort and visual fatigue.

Results

After the reading task, the FTBUT of each group significantly decreased (all P < 0.05). Notably, all tear film stability indicators significantly changed in Group 4. The incomplete blink rate in all the groups tended to increase over time (all P < 0.05). Among the four groups, Group 4 had a significantly greater incomplete blink rate and partial blink ratio (P < 0.05), along with a greater subjective fatigue score, than did Group 1 (P < 0.01). The frequency of incomplete blinks (r = 0.29, P = 0.03) was positively correlated with the visual fatigue score.

Conclusions

Reading in a dark environment with a bright screen led to the most significant instability of the tear film, visual fatigue, and changes in blink patterns. Therefore, it is advisable to avoid reading under such conditions.

目的：研究不同环境照度和屏幕亮度对手机阅读时泪膜稳定性、视觉疲劳和眨眼模式的影响。方法：本前瞻性研究选取30名年轻受试者，根据环境照度和屏幕亮度完成4个实验：第一组：明亮的房间，明亮的屏幕；第二组：暗室，暗屏；第三组：明亮房间，暗幕；第四组：暗室，明屏。在每个实验中，参与者都要完成一项30分钟的手机阅读任务。在读取前后测量泪膜稳定性指标，包括荧光素撕裂破裂时间（FTBUT）、无创撕裂破裂时间、撕裂半月板高度、脂质层厚度。在读取过程中，红外摄像机记录下眨眼相关参数。主观问卷评估舒适度和视觉疲劳。结果：阅读任务结束后，各组的FTBUT均显著降低（P均为 ）。结论：在明亮屏幕的黑暗环境中阅读导致泪膜不稳定、视觉疲劳和眨眼模式改变最为显著。因此，建议避免在这种情况下阅读。

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引用次数: 0