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Noncontrast Myocardial Characterization in Acute Myocardial Infarction Using Electron Density Imaging. 电子密度成像在急性心肌梗死中的非致密性心肌表征。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2023-09-27 DOI: 10.1097/RTI.0000000000000749
Gaston A Rodriguez-Granillo, Juan Cirio, Jose F Vila, Eran Langzam, Thomas Ivanc, Lucia Fontana, Amalia Descalzo, Bibiana Rubilar, Pedro Lylyk

Purpose: Spectral computed tomography (CT) enables improved tissue characterization, although virtually all research has focused on contrast-enhanced examinations. We hypothesized that changes in myocardial tissue related to acute myocardial infarction (AMI) might potentially be identified without the need for contrast administration using electron density (ED) imaging.

Patients and methods: This retrospective observational study involved a small series (n = 15) of patients admitted to our institution with a first AMI without signs of hemodynamic instability and identification of a culprit vessel with invasive coronary angiography during the same admission, who also underwent a noncontrast, low-dose chest CT using a dual-layer spectral CT scanner. Images were assessed in search of dark areas with low density on ED imaging, and the mean percentage ED relative to water (%EDW) was calculated.

Results: Using a qualitative approach, ED assessment enabled the identification of 11/15 (73%) affected coronary territories, with a sensitivity of 73% (95% CI: 45; 92%) and a specificity of 87% (95% CI: 69; 96%). AMI segments showed significantly lower ED values than the remote myocardium (103.8 ± 0.8 vs 104.3 ± 0.6 %EDW, P < 0.0001), and a threshold below 103.9 %EDW had a sensitivity of 66% and specificity of 79% for the identification of AMI. In a control group of patients without a history of cardiovascular disease, none had areas with focal reduction of ED following the shape of the myocardial wall.

Conclusions: In our preliminary series, ED imaging showed the potential to enable the identification of myocardial tissue changes related to AMI without iodinated contrast requirement.

目的:光谱计算机断层扫描(CT)能够改善组织特征,尽管几乎所有的研究都集中在对比增强检查上。我们假设,与急性心肌梗死(AMI)相关的心肌组织变化可能在不需要使用电子密度(ED)成像进行对比剂给药的情况下被识别。患者和方法:这项回顾性观察性研究涉及一小组(n=15)患者,他们因首次AMI入院,没有血液动力学不稳定的迹象,并在同一入院期间通过有创冠状动脉造影确定了罪魁祸首血管,他们还使用双层光谱CT扫描仪进行了非光栅低剂量胸部CT检查。在ED成像中评估图像以寻找低密度的暗区,并计算ED相对于水的平均百分比(%EDW)。结果:采用定性方法,ED评估能够识别11/15(73%)受影响的冠状动脉区域,敏感性为73%(95%CI:45;92%),特异性为87%(95%CI:69;96%)。AMI段的ED值明显低于远端心肌(103.8±0.8 vs 104.3±0.6 %EDW,P<0.0001),阈值低于103.9 %EDW对AMI的敏感性为66%,特异性为79%。在没有心血管病史的对照组患者中,没有一个区域的ED随心肌壁的形状而局部减少。结论:在我们的初步系列中,ED成像显示出在不需要碘化造影剂的情况下能够识别与AMI相关的心肌组织变化的潜力。
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引用次数: 0
Myocardial Work Measurement With Functional Capacity Evaluation in Primary Systemic Hypertension Patients: Comparison Between Left Ventricle With and Without Hypertrophy. 原发性系统性高血压患者心肌功测量与功能能力评估:左心室有无肥厚的比较。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2022-12-06 DOI: 10.1097/RTI.0000000000000690
Hong Ran, Xiao-Wu Ma, Lin-Lin Wan, Jun-Yi Ren, Jian-Xin Zhang, Ping-Yang Zhang, Matthias Schneider

Objective: Noninvasive measurement of myocardial work (MW) incorporates left ventricular (LV) pressure, and, therefore, allows correction of global longitudinal strain for changing afterload conditions. We sought to investigate MW as a tool to detect early signs of LV dysfunction in primary systemic hypertension patients, particularly with different predictive indices.

Methods and results: None left ventricular hypertrophy (NLVH) and left ventricular hypertrophy (LVH) patients established were all primary systemic hypertension with preserved ejection fraction. Forty in NLVH and forty in LVH according to left ventricular end-diastolic mass index (LVEDmassI) were prospectively enrolled. The following indices of MW were assessed: global work index, global constructive work, global wasted work (GWW), and global work efficiency (GWE). Both global work index ( P =0.348) and global constructive work ( P =0.225) were increased in NLVH and decreased in LVH, and GWW ( P <0.001) was increased significantly in NLVH and increased more in LVH, while GWE ( P <0.001) was decreased significantly in NLVH and decreased more in LVH. The clinical utility of GWW (95% CI: 0.802-0.951) and GWE (95% CI: 0.811-0.950) were verified by receiver-operating characteristic curve analysis showing larger net benefits as evaluated with LVH and control comparisons. In multivariate linear regression analysis, 4-dimenaional LVEDmassI was independently associated with GWE ( P =0.018) in systemic hypertension patients. Assessment of intraobserver and interobserver variability in the MW echocardiographic data documented good interclass correlation coefficients (all >0.85).

Conclusion: GWW and GWE derived from MW are more accurate, sensitive, and reproducible predictors to detect early LV dysfunction in primary systemic hypertension patients, especially in distinguishing the potential functional abnormality of NLVH and LVH, even though the ejection fraction is preserved.

目的:无创心肌功(MW)测量包含左心室(LV)压力,因此可以根据后负荷的变化校正整体纵向应变。我们试图研究将心肌功作为检测原发性系统性高血压患者左心室功能障碍早期征兆的工具,特别是不同的预测指数:无左心室肥厚(NLVH)和左心室肥厚(LVH)患者均为射血分数保留的原发性全身性高血压。根据左心室舒张末期质量指数(LVEDmassI),40 名 NLVH 和 40 名 LVH 患者被纳入前瞻性研究。对以下工作效率指数进行了评估:全局工作指数、全局建设性工作、全局浪费工作(GWW)和全局工作效率(GWE)。全局工作指数(P=0.348)和全局建设性工作(P=0.225)在 NLVH 中均有所增加,而在 LVH 中则有所减少,全局浪费工作(GWW)(P0.85):结论:由MW得出的GWW和GWE是检测原发性系统性高血压患者早期左心室功能障碍的更准确、敏感和可重复的预测指标,尤其是在区分NLVH和LVH的潜在功能异常方面,即使射血分数保持不变。
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引用次数: 0
Pericardial Fat Is Associated With Less Severe Multiorgan Failure Over Time in Patients With Coronavirus Disease-19: The Maastricht Intensive Care COVID Cohort. 随着时间的推移,冠状病毒病患者的心包脂肪与较轻的多器官衰竭有关:马斯特里赫特重症监护新冠肺炎队列。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2023-08-25 DOI: 10.1097/RTI.0000000000000732
Eda Aydeniz, Vanessa Weberndorfer, Lloyd Brandts, Martijn W Smulders, Thijs T W van Herpt, Bibi Martens, Kevin Vernooy, Dominik Linz, Iwan C C van der Horst, Joachim E Wildberger, Bas C T van Bussel, Rob G H Driessen, Casper Mihl

Purpose: Pericardial fat (PF) and epicardial adipose tissue (EAT) may enhance the proinflammatory response in corona virus-19 (COVID-19) patients. Higher PF and EAT volumes might result in multiorgan failure and explain unfavorable trajectories.The aim of this study was to examine the association between the volume of PF and EAT and multiorgan failure over time.

Materials and methods: All mechanically ventilated COVID-19 patients with an available chest computed tomography were prospectively included (March-June 2020). PF and EAT volumes were quantified using chest computed tomography scans. Patients were categorized into sex-specific PF and EAT tertiles. Variables to calculate Sequential Organ Failure Assessment (SOFA) scores were collected daily to indicate multiorgan failure. Linear mixed-effects regression was used to investigate the association between tertiles for PF and EAT volumes separately and serial SOFA scores over time. All models were adjusted.

Results: Sixty-three patients were divided into PF and EAT tertiles, with median PF volumes of 131.4 mL (IQR [interquartile range]: 115.7, 143.2 mL), 199.8 mL (IQR: 175.9, 221.6 mL), and 318.8 mL (IQR: 281.9, 376.8 mL) and median EAT volumes of 69.6 mL (IQR: 57.0, 79.4 mL), 107.9 mL (IQR: 104.6, 115.1 mL), and 163.8 mL (IQR: 146.5, 203.1 mL). Patients in the highest PF tertile had a statistically significantly lower SOFA score over time (1.3 [-2.5, -0.1], P =0.033) compared with the lowest PF tertile. EAT tertiles were not significantly associated with SOFA scores over time.

Conclusion: A higher PF volume is associated with less multiorgan failure in mechanically ventilated COVID-19 patients. EAT volumes were not associated with multiorgan failure.

目的:心包脂肪(PF)和心外膜脂肪组织(EAT)可能增强新冠肺炎患者的促炎反应。较高的PF和EAT体积可能会导致多器官衰竭,并解释不利的轨迹。本研究的目的是检查PF和EAT的体积与多器官衰竭之间的关系。材料和方法:前瞻性纳入所有具有可用胸部计算机断层扫描的机械通气新冠肺炎患者(2020年3月至6月)。使用胸部计算机断层扫描对PF和EAT体积进行量化。将患者分为性别特异性PF和EAT三分位。每天收集用于计算顺序器官衰竭评估(SOFA)评分的变量,以指示多器官衰竭。线性混合效应回归用于研究PF和EAT体积的三分位数与一段时间内SOFA系列评分之间的相关性。所有型号都进行了调整。结果:63名患者被分为PF和EAT三分位数,中位PF体积分别为131.4 mL(IQR[四分位数间距]:115.7143.2 mL)、199.8 mL(IQR:175.9221.6 mL)和318.8 mL(IQ:281.9376.8 mL),和163.8 mL(IQR:146.5203.1 mL)。随着时间的推移,PF三分位数最高的患者的SOFA评分(1.3[-2.5,-0.1],P=0.033)与PF三分位最低的患者相比,在统计学上显著降低。随着时间的推移,EAT三分位数与SOFA得分没有显著相关性。结论:机械通气新冠肺炎患者PF容量越高,多器官衰竭越少。EAT容量与多器官衰竭无关。
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引用次数: 0
A Novel Dual Energy Computed Tomography Score Correlates With Postoperative Outcomes in Chronic Thromboembolic Pulmonary Hypertension. 新型双能量计算机断层扫描评分与慢性血栓栓塞性肺动脉高压的术后效果相关。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2023-07-07 DOI: 10.1097/RTI.0000000000000724
Rahul D Renapurkar, Jennifer Bullen, Alain Rizk, Mostafa Abozeed, Wadih Karim, Mnahi Bin Saeedan, Michael Z Tong, Gustavo A Heresi

Purpose: To compare dual-energy computed tomography (DECT) based qualitative and quantitative parameters in chronic thromboembolic pulmonary hypertension with various postoperative primary and secondary endpoints.

Materials and methods: This was a retrospective analysis of 64 patients with chronic thromboembolic pulmonary hypertension who underwent DECT. First, a clot score was calculated by assigning the following score: pulmonary trunk-5, each main pulmonary artery-4, each lobar-3, each segmental-2, and subsegmental-1 per lobe; the sum total was then calculated. The perfusion defect (PD) score was calculated by assigning 1 point to each segmental PD. The combined score was calculated by adding clot and PD scores. For quantitative evaluation, we calculated perfused blood volume (PBV) (%) of each lung and the sum of both lungs. Primary endpoints included testing association between combined score and total PBV with change in mean pulmonary arterial pressure ([mPAP], change calculated as preop minus postop values). Secondary endpoints included explorative analysis of the correlation between combined score and PBV with change in preoperative and postoperative pulmonary vascular resistance, change in preoperative 6-minute walk distance (6MWD), and immediate postoperative complications such as reperfusion edema, ECMO placement, stroke, death and mechanical ventilation for more than 48 hours, all within 1 month of surgery.

Results: Higher combined scores were associated with larger decreases in mPAP ( =0.27, P =0.036). On average, the decrease in mPAP (pre mPAP-post mPAP) increased by 2.2 mm Hg (95% CI: -0.6, 5.0) with each 10 unit increase in combined score. The correlation between total PBV and change in mPAP was small and not statistically significant. During an exploratory analysis, higher combined scores were associated with larger increases in 6MWD at 6 months postprocedure ( =0.55, P =0.002).

Conclusion: Calculation of DECT-based combined score offers potential in the evaluation of hemodynamic response to surgery. This response can also be objectively quantified.

目的:比较基于双能计算机断层扫描(DECT)的慢性血栓栓塞性肺动脉高压的定性和定量参数与各种术后主要和次要终点:这是对 64 名接受 DECT 检查的慢性血栓栓塞性肺动脉高压患者的回顾性分析。首先,通过以下评分计算血栓评分:肺动脉干-5 分,每个主肺动脉-4 分,每个肺叶-3 分,每个肺段-2 分,每个肺叶亚段-1 分;然后计算总和。灌注缺损(PD)得分的计算方法是:每个节段的灌注缺损得 1 分。血块和 PD 分数相加后计算出综合分数。为了进行定量评估,我们计算了每个肺的灌注血量(PBV)(%)和两个肺的总和。主要终点包括测试综合评分和总灌注血量与平均肺动脉压([mPAP],以术前值减去术后值计算)变化之间的关联。次要终点包括对综合评分和 PBV 与术前和术后肺血管阻力变化、术前 6 分钟步行距离(6MWD)变化以及术后 1 个月内再灌注水肿、ECMO 置入、中风、死亡和机械通气超过 48 小时等术后即刻并发症之间的相关性进行探索性分析:综合评分越高,mPAP 下降幅度越大(=0.27,P=0.036)。综合评分每增加 10 个单位,mPAP(术前 mPAP-术后 mPAP)平均下降 2.2 mm Hg(95% CI:-0.6,5.0)。总 PBV 与 mPAP 变化之间的相关性较小,且无统计学意义。在探索性分析中,综合评分越高,术后 6 个月时 6MWD 的增加幅度越大(=0.55,P =0.002):结论:计算基于 DECT 的综合评分可用于评估手术后的血流动力学反应。结论:计算基于 DECT 的综合评分在评估手术后的血流动力学反应方面具有潜力,这种反应也可以客观量化。
{"title":"A Novel Dual Energy Computed Tomography Score Correlates With Postoperative Outcomes in Chronic Thromboembolic Pulmonary Hypertension.","authors":"Rahul D Renapurkar, Jennifer Bullen, Alain Rizk, Mostafa Abozeed, Wadih Karim, Mnahi Bin Saeedan, Michael Z Tong, Gustavo A Heresi","doi":"10.1097/RTI.0000000000000724","DOIUrl":"10.1097/RTI.0000000000000724","url":null,"abstract":"<p><strong>Purpose: </strong>To compare dual-energy computed tomography (DECT) based qualitative and quantitative parameters in chronic thromboembolic pulmonary hypertension with various postoperative primary and secondary endpoints.</p><p><strong>Materials and methods: </strong>This was a retrospective analysis of 64 patients with chronic thromboembolic pulmonary hypertension who underwent DECT. First, a clot score was calculated by assigning the following score: pulmonary trunk-5, each main pulmonary artery-4, each lobar-3, each segmental-2, and subsegmental-1 per lobe; the sum total was then calculated. The perfusion defect (PD) score was calculated by assigning 1 point to each segmental PD. The combined score was calculated by adding clot and PD scores. For quantitative evaluation, we calculated perfused blood volume (PBV) (%) of each lung and the sum of both lungs. Primary endpoints included testing association between combined score and total PBV with change in mean pulmonary arterial pressure ([mPAP], change calculated as preop minus postop values). Secondary endpoints included explorative analysis of the correlation between combined score and PBV with change in preoperative and postoperative pulmonary vascular resistance, change in preoperative 6-minute walk distance (6MWD), and immediate postoperative complications such as reperfusion edema, ECMO placement, stroke, death and mechanical ventilation for more than 48 hours, all within 1 month of surgery.</p><p><strong>Results: </strong>Higher combined scores were associated with larger decreases in mPAP ( =0.27, P =0.036). On average, the decrease in mPAP (pre mPAP-post mPAP) increased by 2.2 mm Hg (95% CI: -0.6, 5.0) with each 10 unit increase in combined score. The correlation between total PBV and change in mPAP was small and not statistically significant. During an exploratory analysis, higher combined scores were associated with larger increases in 6MWD at 6 months postprocedure ( =0.55, P =0.002).</p><p><strong>Conclusion: </strong>Calculation of DECT-based combined score offers potential in the evaluation of hemodynamic response to surgery. This response can also be objectively quantified.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":"178-184"},"PeriodicalIF":3.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10122293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Atrial Dysfunction in Apical Hypertrophic Cardiomyopathy: Assessed by Cardiovascular Magnetic Resonance Feature-tracking. 尖端肥厚型心肌病的左心房功能障碍:心血管磁共振特征追踪评估。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2023-06-20 DOI: 10.1097/RTI.0000000000000722
Yingxia Yang, Minjie Lu, Xuechun Guan, Shihua Zhao, Liling Long

Purpose: To evaluate the left atrial (LA) function in participants with apical hypertrophic cardiomyopathy (AHCM) by cardiovascular magnetic resonance feature tracking (CMR-FT).

Materials and methods: Thirty typical AHCM (TAHCM) patients, 23 subclinical AHCM (SAHCM) patients and 32 normal healthy volunteers who underwent CMR exam were retrospectively analyzed. LA reservoir, conduit, and contractile function were quantified by volumetric and CMR-FT derived strain and strain rate (SR) parameters from 2-chamber and 4-chamber cine imaging.

Results: Compared with healthy participants, both TAHCM and SAHCM patients had impaired LA reservoir function (total strain [%]: TAHCM 31.3±12.2, SAHCM 31.8±12.3, controls 40.4±10.7, P <0.01; total SR [/s]: TAHCM 1.1±0.4, SAHCM 1.1±0.5, controls 1.4 ± 0.4, P <0.01) and conduit function (passive strain [%]: TAHCM 14.4±7.6, SAHCM 16.4±8.8, controls 23.3±8.1, P <0.01; passive SR [/s]: TAHCM -0.5±0.3, SAHCM -0.6±0.3, controls -1.0±0.4, P <0.01). Regarding contraction function, although TAHCM and SAHCM patients had preserved active emptying fraction and strain (all P >0.05), patients with TAHCM had the lowest active SR value among the 3 groups ( P= 0.03). LA reservoir and conduit strain were both significantly associated with left ventricular mass index and maximal wall thickness (all P <0.05). A moderate correlation between LA passive SR and left ventricular cardiac index ( P <0.01).

Conclusions: The LA reservoir and conduit function are predominately impaired and appeared in both SAHCM and TAHCM patients.

目的:通过心血管磁共振特征追踪(CMR-FT)评估心尖肥厚型心肌病(AHCM)患者的左心房(LA)功能:回顾性分析30名典型AHCM(TAHCM)患者、23名亚临床AHCM(SAHCM)患者和32名接受CMR检查的正常健康志愿者。通过两腔和四腔电影成像的容积参数和 CMR-FT 导出的应变和应变率(SR)参数对 LA 储库、导管和收缩功能进行量化:与健康参试者相比,TAHCM 和 SAHCM 患者的 LA 储库功能均受损(总应变[%]:TAHCM 31.3±12 mmHg,SAHCM 31.3±12 mmHg):总应变[%]:TAHCM 31.3±12.2,SAHCM 31.8±12.3,对照组 40.4±10.7,P 0.05),TAHCM 患者的活动 SR 值在三组患者中最低(P= 0.03)。LA 储库和导水管应变均与左心室质量指数和最大室壁厚度显著相关(均为 P 结论:LA 储库和导水管应变与左心室质量指数和最大室壁厚度显著相关(均为 PSAHCM和TAHCM患者的LA储腔和导水管功能主要受损。
{"title":"Left Atrial Dysfunction in Apical Hypertrophic Cardiomyopathy: Assessed by Cardiovascular Magnetic Resonance Feature-tracking.","authors":"Yingxia Yang, Minjie Lu, Xuechun Guan, Shihua Zhao, Liling Long","doi":"10.1097/RTI.0000000000000722","DOIUrl":"10.1097/RTI.0000000000000722","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the left atrial (LA) function in participants with apical hypertrophic cardiomyopathy (AHCM) by cardiovascular magnetic resonance feature tracking (CMR-FT).</p><p><strong>Materials and methods: </strong>Thirty typical AHCM (TAHCM) patients, 23 subclinical AHCM (SAHCM) patients and 32 normal healthy volunteers who underwent CMR exam were retrospectively analyzed. LA reservoir, conduit, and contractile function were quantified by volumetric and CMR-FT derived strain and strain rate (SR) parameters from 2-chamber and 4-chamber cine imaging.</p><p><strong>Results: </strong>Compared with healthy participants, both TAHCM and SAHCM patients had impaired LA reservoir function (total strain [%]: TAHCM 31.3±12.2, SAHCM 31.8±12.3, controls 40.4±10.7, P <0.01; total SR [/s]: TAHCM 1.1±0.4, SAHCM 1.1±0.5, controls 1.4 ± 0.4, P <0.01) and conduit function (passive strain [%]: TAHCM 14.4±7.6, SAHCM 16.4±8.8, controls 23.3±8.1, P <0.01; passive SR [/s]: TAHCM -0.5±0.3, SAHCM -0.6±0.3, controls -1.0±0.4, P <0.01). Regarding contraction function, although TAHCM and SAHCM patients had preserved active emptying fraction and strain (all P >0.05), patients with TAHCM had the lowest active SR value among the 3 groups ( P= 0.03). LA reservoir and conduit strain were both significantly associated with left ventricular mass index and maximal wall thickness (all P <0.05). A moderate correlation between LA passive SR and left ventricular cardiac index ( P <0.01).</p><p><strong>Conclusions: </strong>The LA reservoir and conduit function are predominately impaired and appeared in both SAHCM and TAHCM patients.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":"157-164"},"PeriodicalIF":3.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11027970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9723532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Related Differences of Left Atrial Strain in Patients With Hypertension Using Cardiac Magnetic Resonance Feature Tracking. 利用心脏磁共振特征追踪高血压患者左心房应变的性别差异。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-05-01 Epub Date: 2023-11-06 DOI: 10.1097/RTI.0000000000000760
Zhaoxia Yang, Jinyang Wen, Dazong Tang, Yi Luo, Chunlin Xiang, Liming Xia, Lu Huang

Purpose: Previous studies demonstrated the impact of sex on left ventricular (LV) strain in patients with essential hypertension. However, little is known about the effect of sex on left atrial (LA) strain in patients with hypertension. This study aimed to explore the sex-related differences of LA strain by using cardiac magnetic resonance feature tracking in patients with hypertension and preserved LV ejection fraction.

Materials and methods: One hundred and fifty hypertensive patients (100 men and 50 women) and 105 age-matched and sex-matched normotensive controls (70 men and 35 women) were retrospectively enrolled and underwent cardiac magnetic resonance examination. LA strain parameters included LA reservoir strain (εs), conduit strain (εe), pump strain (εa), and their corresponding strain rate (SRs, SRe, and SRa).

Results: Men had significantly higher LV mass index, lower εs and εe than women in both patients and controls (all P <0.05). LA strain and strain rate were significantly reduced in hypertensive patients compared with controls, both in men and women (all P <0.05). In men, hypertension and its interaction were associated with increased LV mass index and decreased εs and εe. In multivariable analysis, men, LV ejection fraction, and LA minimum volume index remained independent determinants of εs and εe in all hypertensive patients (all P <0.05).

Conclusion: LA strain was significantly impaired in hypertensive patients, and men had more impaired LA strain than women. These findings further emphasize the sex-related differences in the response of LA strain to hypertension in the early stage.

目的:以往的研究证实了性别对原发性高血压患者左心室(LV)应变的影响。然而,关于性别对高血压患者左心房(LA)应变的影响知之甚少。本研究旨在通过心脏磁共振特征追踪在保留左室射血分数的高血压患者中探讨LA株的性别差异。材料与方法:回顾性纳入150例高血压患者(男性100例,女性50例)和105例年龄匹配、性别匹配的正常血压对照组(男性70例,女性35例),并行心脏磁共振检查。LA应变参数包括LA储层应变(εs)、管道应变(εe)、泵应变(εa)及其对应的应变率(SRs、SRe、SRa)。结果:男性左室质量指数明显高于女性,εs和εe明显低于女性(p < 0.05)。结论:高血压患者LA菌株明显受损,且男性LA菌株受损程度明显高于女性。这些发现进一步强调了LA菌株对早期高血压反应的性别差异。
{"title":"Sex-Related Differences of Left Atrial Strain in Patients With Hypertension Using Cardiac Magnetic Resonance Feature Tracking.","authors":"Zhaoxia Yang, Jinyang Wen, Dazong Tang, Yi Luo, Chunlin Xiang, Liming Xia, Lu Huang","doi":"10.1097/RTI.0000000000000760","DOIUrl":"10.1097/RTI.0000000000000760","url":null,"abstract":"<p><strong>Purpose: </strong>Previous studies demonstrated the impact of sex on left ventricular (LV) strain in patients with essential hypertension. However, little is known about the effect of sex on left atrial (LA) strain in patients with hypertension. This study aimed to explore the sex-related differences of LA strain by using cardiac magnetic resonance feature tracking in patients with hypertension and preserved LV ejection fraction.</p><p><strong>Materials and methods: </strong>One hundred and fifty hypertensive patients (100 men and 50 women) and 105 age-matched and sex-matched normotensive controls (70 men and 35 women) were retrospectively enrolled and underwent cardiac magnetic resonance examination. LA strain parameters included LA reservoir strain (εs), conduit strain (εe), pump strain (εa), and their corresponding strain rate (SRs, SRe, and SRa).</p><p><strong>Results: </strong>Men had significantly higher LV mass index, lower εs and εe than women in both patients and controls (all P <0.05). LA strain and strain rate were significantly reduced in hypertensive patients compared with controls, both in men and women (all P <0.05). In men, hypertension and its interaction were associated with increased LV mass index and decreased εs and εe. In multivariable analysis, men, LV ejection fraction, and LA minimum volume index remained independent determinants of εs and εe in all hypertensive patients (all P <0.05).</p><p><strong>Conclusion: </strong>LA strain was significantly impaired in hypertensive patients, and men had more impaired LA strain than women. These findings further emphasize the sex-related differences in the response of LA strain to hypertension in the early stage.</p>","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":" ","pages":"W40-W47"},"PeriodicalIF":3.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes of Surgical Revascularization Strategies Guided by Quantitative Flow Ratio in Primary Noncoronary Cardiac Surgery. 原发性非冠状动脉心脏手术中以定量血流比率为指导的手术血管再通策略的临床疗效
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-30 DOI: 10.1097/rti.0000000000000783
Linlin Li, Heng Zhang, Chenfei Rao, Jian Meng, Xingtong Zhou, Chang Liu, Hongguang Fan
Information regarding quantitative flow ratio (QFR) usage in coronary artery bypass grafting (CABG) is lacking. We compared the incidence of postoperative long-term adverse cardiovascular and cerebrovascular events after QFR-guided or coronary angiography-guided adult cardiac surgery with concurrent bypass surgery.
有关冠状动脉旁路移植术(CABG)中使用定量血流比(QFR)的信息尚缺。我们比较了在 QFR 或冠状动脉造影引导下进行成人心脏手术并同时进行搭桥手术后,术后长期不良心脑血管事件的发生率。
{"title":"Clinical Outcomes of Surgical Revascularization Strategies Guided by Quantitative Flow Ratio in Primary Noncoronary Cardiac Surgery.","authors":"Linlin Li, Heng Zhang, Chenfei Rao, Jian Meng, Xingtong Zhou, Chang Liu, Hongguang Fan","doi":"10.1097/rti.0000000000000783","DOIUrl":"https://doi.org/10.1097/rti.0000000000000783","url":null,"abstract":"Information regarding quantitative flow ratio (QFR) usage in coronary artery bypass grafting (CABG) is lacking. We compared the incidence of postoperative long-term adverse cardiovascular and cerebrovascular events after QFR-guided or coronary angiography-guided adult cardiac surgery with concurrent bypass surgery.","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":"10 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140833255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiologic Manifestations of Mycobacterium chimaera Infection After Open Heart Surgery. 开放式心脏手术后奇异分枝杆菌感染的放射学表现。
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-25 DOI: 10.1097/rti.0000000000000779
Andrew E Moore, Tuan Ngo, Joseph Donald, Samira Shorey, Ram Sivakumar, Vivek Velagapudi, Christopher M Walker
The objective of this study is to identify and detail the radiologic manifestations of surgical site and disseminated Mycobacterium chimaera (MC) infection. The aim is to facilitate early identification and diagnosis of MC, considering its indolent nature and the challenges involved in clinically and pathologically establishing the diagnosis.
本研究旨在确定和详细描述手术部位和播散性分枝杆菌(MC)感染的放射学表现。考虑到 MC 的隐匿性以及临床和病理诊断所面临的挑战,本研究旨在促进 MC 的早期识别和诊断。
{"title":"Radiologic Manifestations of Mycobacterium chimaera Infection After Open Heart Surgery.","authors":"Andrew E Moore, Tuan Ngo, Joseph Donald, Samira Shorey, Ram Sivakumar, Vivek Velagapudi, Christopher M Walker","doi":"10.1097/rti.0000000000000779","DOIUrl":"https://doi.org/10.1097/rti.0000000000000779","url":null,"abstract":"The objective of this study is to identify and detail the radiologic manifestations of surgical site and disseminated Mycobacterium chimaera (MC) infection. The aim is to facilitate early identification and diagnosis of MC, considering its indolent nature and the challenges involved in clinically and pathologically establishing the diagnosis.","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":"247 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140800047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Performance of 18F-FDG Positron Emission Tomography/Computed Tomography and Blood Test Parameters for Pulmonary Inflammatory Pseudotumor. 18F-FDG正电子发射断层扫描/计算机断层扫描和血液检测参数对肺部炎症性假瘤的诊断性能
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-18 DOI: 10.1097/rti.0000000000000780
Bo Pan, Yanming Wang, Zehua Zhu, Xingxing Zhu
Pulmonary inflammatory pseudotumor (PIP) is an inflammatory proliferative tumor-like lesion that frequently exhibits hypermetabolism on 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography imaging (PET/CT) and is readily misdiagnosed as a malignant tumor. The purpose of this study was to identify PIP by combining PET/computed tomography metabolic and blood test characteristics with machine learning.
肺部炎性假瘤(PIP)是一种炎性增生性肿瘤样病变,在18F-氟脱氧葡萄糖(FDG)正电子发射断层扫描/计算机断层扫描成像(PET/CT)上经常表现为高代谢,容易被误诊为恶性肿瘤。本研究的目的是通过将 PET/计算机断层扫描代谢特征和血液检测特征与机器学习相结合来识别 PIP。
{"title":"Diagnostic Performance of 18F-FDG Positron Emission Tomography/Computed Tomography and Blood Test Parameters for Pulmonary Inflammatory Pseudotumor.","authors":"Bo Pan, Yanming Wang, Zehua Zhu, Xingxing Zhu","doi":"10.1097/rti.0000000000000780","DOIUrl":"https://doi.org/10.1097/rti.0000000000000780","url":null,"abstract":"Pulmonary inflammatory pseudotumor (PIP) is an inflammatory proliferative tumor-like lesion that frequently exhibits hypermetabolism on 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography imaging (PET/CT) and is readily misdiagnosed as a malignant tumor. The purpose of this study was to identify PIP by combining PET/computed tomography metabolic and blood test characteristics with machine learning.","PeriodicalId":49974,"journal":{"name":"Journal of Thoracic Imaging","volume":"22 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140628822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjusting Atrial Size Parameters for Body Surface Area: Does it Affect the Association with Pulmonary Embolism-related Adverse Events? 根据体表面积调整心房大小参数:它会影响肺栓塞相关不良事件吗?
IF 3.3 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-04-18 DOI: 10.1097/rti.0000000000000781
Rachael R Kirkbride, Galit Aviram, Benedikt H Heidinger, Yuval Liberman, Aurelija Libauske, Rokas Liubauskas, Daniela M Tridente, Alexander Brook, Dominique C DaBreo, Antonio C Monteiro Filho, Brett J Carroll, Jason D Matos, Ian C McCormick, Warren J Manning, Diana E Litmanovich
Small left atrial (LA) volume was recently reported to be one of the best predictors of acute pulmonary embolism (PE)-related adverse events (AE). There is currently no data available regarding the impact that body surface area (BSA)-indexing of atrial measurements has on the association with PE-related adverse events. Our aim is to assess the impact of indexing atrial measurements to BSA on the association between computed tomography (CT) atrial measurements and AE.
最近有报道称,左心房(LA)容积小是预测急性肺栓塞(PE)相关不良事件(AE)的最佳指标之一。目前尚无数据显示体表面积(BSA)指数化的心房测量值对与 PE 相关的不良事件的影响。我们的目的是评估将心房测量值与体表面积(BSA)挂钩对计算机断层扫描(CT)心房测量值与 AE 之间关系的影响。
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Journal of Thoracic Imaging
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