Pub Date : 1936-07-01DOI: 10.1136/jnnp.s1-17.65.88
J. Aitchison, J. Kay, I. Lauder
FROM his work the writer concludes that the toxic and Sudanophil granule estimations appear to follow the course of the psychosis, varying directly with the intensity of the disorder. The gradual improvement in the counts observed in recovering cases must be ascribed in part to the general detoxication which is instituted in each patient soon after admission. Though it would be rash to infer from only a few examinations that these estimations have definite and prognostic value, it is suggested that they may prove of considerable assistance. C. S. R.
{"title":"PROGNOSIS AND TREATMENT","authors":"J. Aitchison, J. Kay, I. Lauder","doi":"10.1136/jnnp.s1-17.65.88","DOIUrl":"https://doi.org/10.1136/jnnp.s1-17.65.88","url":null,"abstract":"FROM his work the writer concludes that the toxic and Sudanophil granule estimations appear to follow the course of the psychosis, varying directly with the intensity of the disorder. The gradual improvement in the counts observed in recovering cases must be ascribed in part to the general detoxication which is instituted in each patient soon after admission. Though it would be rash to infer from only a few examinations that these estimations have definite and prognostic value, it is suggested that they may prove of considerable assistance. C. S. R.","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-17.65.88","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63913692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-07-01DOI: 10.1136/jnnp.s1-17.65.74
A R Short
{"title":"Traumatic Aphasia and Alexia.","authors":"A R Short","doi":"10.1136/jnnp.s1-17.65.74","DOIUrl":"https://doi.org/10.1136/jnnp.s1-17.65.74","url":null,"abstract":"","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-17.65.74","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.363
A Guirdham
{"title":"The Body Type of the General Paralytic.","authors":"A Guirdham","doi":"10.1136/jnnp.s1-16.64.363","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.363","url":null,"abstract":"","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.363","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.341
A. Meyer, L. Cook
THE condition known as 6tat marbr6 was first described fully by C. Vogt 24 in 1911 under the name of status marmoratus and has since been the subject of considerable interest and study. Nevertheless no full description has as yet appeared in any English journal, and therefore a brief introductory summary of the main clinical and pathological features may not come amiss. On the clinical side, the condition usually manifests itself from earliest infancy, development is retarded and more or less severe mental defect is of constant appearance. The picture is one of double choreoathetosis, sometimes combined with epilepsy. Loss of emotional control is a prominent feature, and inability to use the muscles of expression and articulation sometimes occurs. In the majority of cases the condition remains stationary; in others severe generalized paralysis, often with torsion spasm and other contractures, eventually supervenes, and death occurs before or during early adult life. Pathologically the most striking feature is the peculiar marblelike appearance of certain areas of the striate body and to a lesser degree of other parts of the brain. The clinical picture, sometimes known as Vogt's disease, is considered by some to be sufficiently characteristic to be diagnosed during life, but, as we shall point out later, there are reasons for believing that the condition is not a clear-cut clinical or pathological entity. Although uncommon, the condition is probably not so rare as might at first appear. It is probable that the majority of cases have failed to come under the care of competent neurologists; some may have been attributed to meningitis or encephalitis lethargica, while others have almost certainly been overlooked in institutions or elsewhere amongst a mass of heterogeneous cerebral palsies of childhood.
{"title":"état Marbré","authors":"A. Meyer, L. Cook","doi":"10.1136/jnnp.s1-16.64.341","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.341","url":null,"abstract":"THE condition known as 6tat marbr6 was first described fully by C. Vogt 24 in 1911 under the name of status marmoratus and has since been the subject of considerable interest and study. Nevertheless no full description has as yet appeared in any English journal, and therefore a brief introductory summary of the main clinical and pathological features may not come amiss. On the clinical side, the condition usually manifests itself from earliest infancy, development is retarded and more or less severe mental defect is of constant appearance. The picture is one of double choreoathetosis, sometimes combined with epilepsy. Loss of emotional control is a prominent feature, and inability to use the muscles of expression and articulation sometimes occurs. In the majority of cases the condition remains stationary; in others severe generalized paralysis, often with torsion spasm and other contractures, eventually supervenes, and death occurs before or during early adult life. Pathologically the most striking feature is the peculiar marblelike appearance of certain areas of the striate body and to a lesser degree of other parts of the brain. The clinical picture, sometimes known as Vogt's disease, is considered by some to be sufficiently characteristic to be diagnosed during life, but, as we shall point out later, there are reasons for believing that the condition is not a clear-cut clinical or pathological entity. Although uncommon, the condition is probably not so rare as might at first appear. It is probable that the majority of cases have failed to come under the care of competent neurologists; some may have been attributed to meningitis or encephalitis lethargica, while others have almost certainly been overlooked in institutions or elsewhere amongst a mass of heterogeneous cerebral palsies of childhood.","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63913372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.369
I T has occasionally been said of organic diseases of the nervous system that while constituting a most interesting field of study in applied physiology and pathology, they are therapeutically destitute. An ardent neurologist might have replied that treatment in organic neurology at all times compared favourably with that in organic medical diseases, such as chronic conditions of the heart, liver and kidneys. We utter a truism in adding that all advance in knowledge of the setiology, pathology and diagnosis of a disease inevitably leads to increased understanding of the possible means of treatment. It is to these aspects of organic disease of the nervous system that most neurological research has been directed, with many brilliant results. Nevertheless, in reviewing the progress of neurology during recent years, it is evident that increasing attention has been paid to treatment per se and that the advances have been considerable. Several diseases, formerly considered almost untreatable apart from general care and management, are now subjected to direct attack. Foremost among these is that form of progressive syphilitic meningoencephalitis, popularly though unfortunately known as ' general paralysis of the insane.' The application of malarial therapy undoubtedly inhibits the malady in the majority of early cases with the result that after a number of years, varying from two to six, the cerebrospinal fluid becomes normal, losing its increased protein content, positive Wassermann reaction and Lange curve. Patients are known among the first to be treated in this country-some 14 years ago-who still survive and in some instances remain useful members of society. An average of the available statistics indicates that approximately 35 per cent. of all cases treated-irrespective of the stage of the disease-show good and lasting remissions, while in a fair proportion of the remainder improvement or arrest of the disease occurs. Compare this with the prognosis invariably given prior to the introduction of malarial treatment
{"title":"Neurological Therapeutics","authors":"","doi":"10.1136/jnnp.s1-16.64.369","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.369","url":null,"abstract":"I T has occasionally been said of organic diseases of the nervous system that while constituting a most interesting field of study in applied physiology and pathology, they are therapeutically destitute. An ardent neurologist might have replied that treatment in organic neurology at all times compared favourably with that in organic medical diseases, such as chronic conditions of the heart, liver and kidneys. We utter a truism in adding that all advance in knowledge of the setiology, pathology and diagnosis of a disease inevitably leads to increased understanding of the possible means of treatment. It is to these aspects of organic disease of the nervous system that most neurological research has been directed, with many brilliant results. Nevertheless, in reviewing the progress of neurology during recent years, it is evident that increasing attention has been paid to treatment per se and that the advances have been considerable. Several diseases, formerly considered almost untreatable apart from general care and management, are now subjected to direct attack. Foremost among these is that form of progressive syphilitic meningoencephalitis, popularly though unfortunately known as ' general paralysis of the insane.' The application of malarial therapy undoubtedly inhibits the malady in the majority of early cases with the result that after a number of years, varying from two to six, the cerebrospinal fluid becomes normal, losing its increased protein content, positive Wassermann reaction and Lange curve. Patients are known among the first to be treated in this country-some 14 years ago-who still survive and in some instances remain useful members of society. An average of the available statistics indicates that approximately 35 per cent. of all cases treated-irrespective of the stage of the disease-show good and lasting remissions, while in a fair proportion of the remainder improvement or arrest of the disease occurs. Compare this with the prognosis invariably given prior to the introduction of malarial treatment","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.369","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63913416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1097/00005053-193703000-00022
A Meyer, L C Cook
{"title":"état Marbré.","authors":"A Meyer, L C Cook","doi":"10.1097/00005053-193703000-00022","DOIUrl":"https://doi.org/10.1097/00005053-193703000-00022","url":null,"abstract":"","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00005053-193703000-00022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.367
G de M Rudolf
{"title":"Tonic Pupils with Absent Tendon Reflexes in Mother and Daughter.","authors":"G de M Rudolf","doi":"10.1136/jnnp.s1-16.64.367","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.367","url":null,"abstract":"","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.367","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.289
W E Dickson, C Worster-Drought
THE clinical and pathological investigation of multiple metastatic tumours of the brain arising from primary bronchial carcinomas is full of snares and pitfalls for the neurological physician, surgeon and pathologist; and, although bronchogenic carcinoma with secondary growths in the brain produces a now fairly well recognized and not uncommon syndrome, its diagnosis is still sometimes made only in the post-mortem room; and even there difficulties may occasionally arise in its recognition. Ten years ago, in a text-book 1 for which one of us, together with Professor J. M. Beattie, was responsible, the statement was made that 'Primary tumours of the lung are extremely rare. Osteomas, chondromas, and sarcomas occur, but the most usual primary tumours are columnar-celled cancers-originating, probably, from some part of the bronchi or from the mucous glands '; while under the heading ' Tumours of the Brain ' we merely stated that 'Secondary cancer is also rare.' Similarly, Ewing, in the third edition (1928) of his book, Neoplastic Diseases, p. 851, gives the frequency of primary malignant tumours of the lung at about 1 per cent. of all cancers, his statistics being taken from between 16,000 and 17,000 autopsies on cancer cases. These statements now require modification, as both in our own experience and in that of others, the frequency of bronchial carcinomas-whether they are described as such or as ' Oat-celled Sarcoma of the Mediastinum ' 2 3: as' Tumours of the Mediastinum and Lung' 4: as' Primary Lung Tumours,' 5
{"title":"Multiple Metastatic Tumours in the Brain arising from Primary Bronchial Carcinoma.","authors":"W E Dickson, C Worster-Drought","doi":"10.1136/jnnp.s1-16.64.289","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.289","url":null,"abstract":"THE clinical and pathological investigation of multiple metastatic tumours of the brain arising from primary bronchial carcinomas is full of snares and pitfalls for the neurological physician, surgeon and pathologist; and, although bronchogenic carcinoma with secondary growths in the brain produces a now fairly well recognized and not uncommon syndrome, its diagnosis is still sometimes made only in the post-mortem room; and even there difficulties may occasionally arise in its recognition. Ten years ago, in a text-book 1 for which one of us, together with Professor J. M. Beattie, was responsible, the statement was made that 'Primary tumours of the lung are extremely rare. Osteomas, chondromas, and sarcomas occur, but the most usual primary tumours are columnar-celled cancers-originating, probably, from some part of the bronchi or from the mucous glands '; while under the heading ' Tumours of the Brain ' we merely stated that 'Secondary cancer is also rare.' Similarly, Ewing, in the third edition (1928) of his book, Neoplastic Diseases, p. 851, gives the frequency of primary malignant tumours of the lung at about 1 per cent. of all cancers, his statistics being taken from between 16,000 and 17,000 autopsies on cancer cases. These statements now require modification, as both in our own experience and in that of others, the frequency of bronchial carcinomas-whether they are described as such or as ' Oat-celled Sarcoma of the Mediastinum ' 2 3: as' Tumours of the Mediastinum and Lung' 4: as' Primary Lung Tumours,' 5","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.289","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurological Therapeutics.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1039050/pdf/jnpsycho00008-0083.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40108373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1936-04-01DOI: 10.1136/jnnp.s1-16.64.375-a
INJURY to both occipital lobes of the brain was a result of a gunshot lesion affecting the posterior part of the skull. As in other cases seen during the war a distinct localization was observed for different qualities of optic disturbance. Blindness for the form of objects was an isolated defect more definitely observed than in any case previously examined. Deficient perception of form and shape was limited to the visual sphere and no disturbance was observed with regard to form and shape in any other region of the brain, e.g. by touching, writing and drawing. Goldstein and Gelb previously described a disturbance for visual form not limited to the visual region in a case of a lesion of the occipital lobe, but according to Kleist's opinion this resulted from a brain lesion outside the visual sphere. M.
{"title":"Psychopathology","authors":"","doi":"10.1136/jnnp.s1-16.64.375-a","DOIUrl":"https://doi.org/10.1136/jnnp.s1-16.64.375-a","url":null,"abstract":"INJURY to both occipital lobes of the brain was a result of a gunshot lesion affecting the posterior part of the skull. As in other cases seen during the war a distinct localization was observed for different qualities of optic disturbance. Blindness for the form of objects was an isolated defect more definitely observed than in any case previously examined. Deficient perception of form and shape was limited to the visual sphere and no disturbance was observed with regard to form and shape in any other region of the brain, e.g. by touching, writing and drawing. Goldstein and Gelb previously described a disturbance for visual form not limited to the visual region in a case of a lesion of the occipital lobe, but according to Kleist's opinion this resulted from a brain lesion outside the visual sphere. M.","PeriodicalId":50117,"journal":{"name":"Journal of Neurology and Psychopathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1936-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/jnnp.s1-16.64.375-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63913475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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