Balaji Vijayam, T. Balaji, M. Balaji, Seshiah Veerasamy, Vinothapooshan Ganesan
The most prevalent metabolic and endocrine perinatal issue is gestational diabetes mellitus (GDM), which is an increasing health problem worldwide. It is a controversial entity, with conflicting guidelines and treatment protocols. In the United States, most doctors utilise a two-step strategy, first with a 50-g non fasting oral glucose challenge test at 24 to 28 weeks and then a 100-g fasting test for women who have a positive screening result. Alternatively, Clinicians take a one step Diabetes in Pregnancy Study Group India (DIPSI) method and perform simply a 75-g two hour fasting oral glucose tolerance test. The DIPSI approach of antenatal GDM screening has been demonstrated to be straightforward, cost effective, easy to use, patient friendly, and convenient. When comparing the findings to the gold standard of the International Association of Diabetes and Pregnancy Study Group (IADPSG), DIPSI shows high specificity and acceptable sensitivity. To maintain euglycemia, glucose monitoring, dietary changes, exercise, and, if necessary, medicines are used. Although insulin therapy is the most common treatment, glyburide and metformin may become more popular. Prenatal testing with nonstress tests and amniotic fluid indices, commencing in the third trimester, is commonly used to assess foetal well-being in women undergoing medication. The delivery technique and time are contentious. Women who have gestational diabetes are at a significant risk of developing type 2 diabetes later in life. As a result, along with routine diabetes screening, lifestyle adjustment should be recommended.
{"title":"Clinical Updates on Screening and Diagnosis Criteria for Gestational Diabetes Mellitus Patients, as well as Therapeutic Management","authors":"Balaji Vijayam, T. Balaji, M. Balaji, Seshiah Veerasamy, Vinothapooshan Ganesan","doi":"10.31254/jmr.2022.8309","DOIUrl":"https://doi.org/10.31254/jmr.2022.8309","url":null,"abstract":"The most prevalent metabolic and endocrine perinatal issue is gestational diabetes mellitus (GDM), which is an increasing health problem worldwide. It is a controversial entity, with conflicting guidelines and treatment protocols. In the United States, most doctors utilise a two-step strategy, first with a 50-g non fasting oral glucose challenge test at 24 to 28 weeks and then a 100-g fasting test for women who have a positive screening result. Alternatively, Clinicians take a one step Diabetes in Pregnancy Study Group India (DIPSI) method and perform simply a 75-g two hour fasting oral glucose tolerance test. The DIPSI approach of antenatal GDM screening has been demonstrated to be straightforward, cost effective, easy to use, patient friendly, and convenient. When comparing the findings to the gold standard of the International Association of Diabetes and Pregnancy Study Group (IADPSG), DIPSI shows high specificity and acceptable sensitivity. To maintain euglycemia, glucose monitoring, dietary changes, exercise, and, if necessary, medicines are used. Although insulin therapy is the most common treatment, glyburide and metformin may become more popular. Prenatal testing with nonstress tests and amniotic fluid indices, commencing in the third trimester, is commonly used to assess foetal well-being in women undergoing medication. The delivery technique and time are contentious. Women who have gestational diabetes are at a significant risk of developing type 2 diabetes later in life. As a result, along with routine diabetes screening, lifestyle adjustment should be recommended.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46504278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Nomali, T. Ramim, S. Nematollahi, Farrokh Sharifi, S. Najafi, K. H. Naeini
Background: One of the major problems in many communities in maternal health is that most pregnant women do not receive the necessary care during pregnancy, while care is provided in various forms by Comprehensive Health Services Centers and Health Centers. However, there is lack of information about pregnancy care status in suburban regions which is necessary on health care planning and policy making. Aims and objectives: The primary objective was to determine the governmental services in prenatal care in the suburban women of Bandar Abbas city in south of Iran. Also, we determined its related factors as secondary objectives. Study design: This was a cross-sectional study. Setting: It was conducted at Bandar Abbas city of Hormozgan province, Iran. The research sample was the population covered by Takhti Comprehensive Health Services Center. Materials and methods: 100 pregnant women and women with children under one year of age who wished to participate in the study were included by cluster sampling in February 2020. The participants did not wish to continue the study or incomplete questionnaires were excluded. The outcome was pregnancy care status which was divided into optimal and not-optimal groups based on receiving at least 6 cares during pregnancy. In order to collect information with interview by trained people, a researcher-structured questionnaire was used, which includes personal information and information about pregnancy status. Statistics: Data were analyzed by SPSS software, version 24.0 and descriptive statistics and statistical tests such as independent sample t test, chi-squared test and Fisher`s exact test. Results: Data of 100 participants with mean age of 28.6 years were statistically analyzed. Most participants (83%) had an optimal status for receiving pregnancy care. Among different personal and pregnancy factors, the timing of prenatal care initiation in the first trimester of pregnancy was significant, as most people who were cared at the first months of pregnancy received optimal care (69 out of 78) (P= 0.007). The care provider (P=0.172) or place of care (P=0.580) had no association with optimal care. Conclusion: Most of the participants in the study had favorable pregnancy care status. People with unfavorable prenatal care status were mainly mothers whose pregnancy care had begun in the third trimester. There was no difference between the two groups in terms of demographic variables, family and previous pregnancy history.
{"title":"Governmental services in prenatal care and its related factors in the suburban women of Bandar Abbas city in the South of Iran: A cross-sectional study","authors":"M. Nomali, T. Ramim, S. Nematollahi, Farrokh Sharifi, S. Najafi, K. H. Naeini","doi":"10.31254/jmr.2022.8307","DOIUrl":"https://doi.org/10.31254/jmr.2022.8307","url":null,"abstract":"Background: One of the major problems in many communities in maternal health is that most pregnant women do not receive the necessary care during pregnancy, while care is provided in various forms by Comprehensive Health Services Centers and Health Centers. However, there is lack of information about pregnancy care status in suburban regions which is necessary on health care planning and policy making. Aims and objectives: The primary objective was to determine the governmental services in prenatal care in the suburban women of Bandar Abbas city in south of Iran. Also, we determined its related factors as secondary objectives. Study design: This was a cross-sectional study. Setting: It was conducted at Bandar Abbas city of Hormozgan province, Iran. The research sample was the population covered by Takhti Comprehensive Health Services Center. Materials and methods: 100 pregnant women and women with children under one year of age who wished to participate in the study were included by cluster sampling in February 2020. The participants did not wish to continue the study or incomplete questionnaires were excluded. The outcome was pregnancy care status which was divided into optimal and not-optimal groups based on receiving at least 6 cares during pregnancy. In order to collect information with interview by trained people, a researcher-structured questionnaire was used, which includes personal information and information about pregnancy status. Statistics: Data were analyzed by SPSS software, version 24.0 and descriptive statistics and statistical tests such as independent sample t test, chi-squared test and Fisher`s exact test. Results: Data of 100 participants with mean age of 28.6 years were statistically analyzed. Most participants (83%) had an optimal status for receiving pregnancy care. Among different personal and pregnancy factors, the timing of prenatal care initiation in the first trimester of pregnancy was significant, as most people who were cared at the first months of pregnancy received optimal care (69 out of 78) (P= 0.007). The care provider (P=0.172) or place of care (P=0.580) had no association with optimal care. Conclusion: Most of the participants in the study had favorable pregnancy care status. People with unfavorable prenatal care status were mainly mothers whose pregnancy care had begun in the third trimester. There was no difference between the two groups in terms of demographic variables, family and previous pregnancy history.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47768859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Binesh, M. Samet, A. Fallah, Najmah Beheshti, S. Shahcheraghi
Desquamative interstitial pneumonia (DIP) is a form of interstitial lung disease that is directly related to smoking. In addition to smoking, other factors have been implicated in its etiology, including: systemic disorders, dangerous materials in the environment, drugs and infectious agents. By reviewing the literature, we find that there are very rare cases that indicate infections as causing DIP. Here the author report on a 58-year-old male who was addict and complained of a dry cough with dyspnea for one month. TBLB was performed and pathology result was consistent with DIP. He received prednisolone 5 mg twice a day, but his symptoms persisted. Open-lung biopsy was performed and it illustrated Aspergillus pneumonia (Chronic necrotizing aspergillosis). He was treated with corticosteroids combined with antifungal agents.
{"title":"Desquamative interstitial pneumonia in association with chronic necrotizing aspergillosis, a case report and literature review","authors":"F. Binesh, M. Samet, A. Fallah, Najmah Beheshti, S. Shahcheraghi","doi":"10.31254/jmr.2022.8302","DOIUrl":"https://doi.org/10.31254/jmr.2022.8302","url":null,"abstract":"Desquamative interstitial pneumonia (DIP) is a form of interstitial lung disease that is directly related to smoking. In addition to smoking, other factors have been implicated in its etiology, including: systemic disorders, dangerous materials in the environment, drugs and infectious agents. By reviewing the literature, we find that there are very rare cases that indicate infections as causing DIP. Here the author report on a 58-year-old male who was addict and complained of a dry cough with dyspnea for one month. TBLB was performed and pathology result was consistent with DIP. He received prednisolone 5 mg twice a day, but his symptoms persisted. Open-lung biopsy was performed and it illustrated Aspergillus pneumonia (Chronic necrotizing aspergillosis). He was treated with corticosteroids combined with antifungal agents.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44398495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faezeh Heidari, J. Ayatollahi, Seyed Mehran Mirallahi, Mohammad Sharifyazdi, S. Mousavi, Zohre Akhondimeybodi, Mahdie Hamidfar, S. Shahcheraghi
COVID-19 produced by SARS-CoV-2 is still distributing and its dangerous cases are related to electrolyte disorders such as calcium levels disturbance. The aim of current study was to investigate serum calcium levels in patients with COVID19 in Shahid Sadoughi Hospital of Yazd. In this cross-sectional study, COVID-19 patients admitted to Shahid Sadoughi Hospital in Yazd from March 2019 to March 2020 were studied. The following data were extracted from patients' records: age, sex, time elapsed from onset of symptoms to hospitalization, severity of COVID-19, serum calcium level at hospitalization, and disease outcome (recovery or death). The serum calcium level mean of patients was 8.2 ±0.7 mg/dl. Most patients had hypocalcemia. Patients who died had lower serum calcium levels than patients who recovered. Therefore, hypocalcemia is common in hospitalized COVID-19 patients and is associated with mortality.
{"title":"Evaluation of serum calcium levels in patients with COVID-19 in Shahid Sadoughi Hospital in Yazd","authors":"Faezeh Heidari, J. Ayatollahi, Seyed Mehran Mirallahi, Mohammad Sharifyazdi, S. Mousavi, Zohre Akhondimeybodi, Mahdie Hamidfar, S. Shahcheraghi","doi":"10.31254/jmr.2022.8303","DOIUrl":"https://doi.org/10.31254/jmr.2022.8303","url":null,"abstract":"COVID-19 produced by SARS-CoV-2 is still distributing and its dangerous cases are related to electrolyte disorders such as calcium levels disturbance. The aim of current study was to investigate serum calcium levels in patients with COVID19 in Shahid Sadoughi Hospital of Yazd. In this cross-sectional study, COVID-19 patients admitted to Shahid Sadoughi Hospital in Yazd from March 2019 to March 2020 were studied. The following data were extracted from patients' records: age, sex, time elapsed from onset of symptoms to hospitalization, severity of COVID-19, serum calcium level at hospitalization, and disease outcome (recovery or death). The serum calcium level mean of patients was 8.2 ±0.7 mg/dl. Most patients had hypocalcemia. Patients who died had lower serum calcium levels than patients who recovered. Therefore, hypocalcemia is common in hospitalized COVID-19 patients and is associated with mortality.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69660497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Sharifyazdi, Faezeh Heidari, Fatemesadat Mousavi Ahmadabadi, Zohre Akhondimeybodi, S. Mousavi, Tahereh Fallah, Mahdie Hamidfar, S. Shahcheraghi
Proper use of antibiotic prophylaxis reduces the rate of postoperative infection, but the administration of inappropriate antibiotics increases the spread of antibiotic-resistant bacterial species as well as prolongs the hospital stay, imposes unnecessary costs, and drug reactions. The purpose of the present study was the investigation of the rate of compliance of antibiotic prophylaxis before surgery with national guidelines in the gynecology ward of Shahid Sadoughi Hospital in Yazd. The present study was a cross-sectional research that was performed in the gynecology ward of Shahid Sadoughi Hospital in Yazd, Iran. The records of 200 patients were reviewed randomly. Patients’ information was including personal information, type of surgery, type of prophylactic antibiotic, dose of antibiotic and time of administration. Finally, the compliance of antibiotic prophylaxis with national guidelines was compared and data analysis was performed using SPSS 22 software. The age mean of patients was 36.6 ±10.5 years. Out of 200 operations, 85 were hysterectomy, 65 cesarean, 30 curettage & abortion and 20 other gynecological operations. The present study showed that the highest compliance was related to the time of antibiotic administration.
{"title":"Determining the degree of compliance of Antibiotic prophylaxis before surgery with national guidelines in the gynecology ward of Shahid Sadoughi Hospital in Yazd","authors":"Mohammad Sharifyazdi, Faezeh Heidari, Fatemesadat Mousavi Ahmadabadi, Zohre Akhondimeybodi, S. Mousavi, Tahereh Fallah, Mahdie Hamidfar, S. Shahcheraghi","doi":"10.31254/jmr.2022.8209","DOIUrl":"https://doi.org/10.31254/jmr.2022.8209","url":null,"abstract":"Proper use of antibiotic prophylaxis reduces the rate of postoperative infection, but the administration of inappropriate antibiotics increases the spread of antibiotic-resistant bacterial species as well as prolongs the hospital stay, imposes unnecessary costs, and drug reactions. The purpose of the present study was the investigation of the rate of compliance of antibiotic prophylaxis before surgery with national guidelines in the gynecology ward of Shahid Sadoughi Hospital in Yazd. The present study was a cross-sectional research that was performed in the gynecology ward of Shahid Sadoughi Hospital in Yazd, Iran. The records of 200 patients were reviewed randomly. Patients’ information was including personal information, type of surgery, type of prophylactic antibiotic, dose of antibiotic and time of administration. Finally, the compliance of antibiotic prophylaxis with national guidelines was compared and data analysis was performed using SPSS 22 software. The age mean of patients was 36.6 ±10.5 years. Out of 200 operations, 85 were hysterectomy, 65 cesarean, 30 curettage & abortion and 20 other gynecological operations. The present study showed that the highest compliance was related to the time of antibiotic administration.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42705305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dear editor In this era of a modern pandemic of this new millennium, called as COVID-19, which has left no borders of the human world untouched on this planet. It is a timeless thing to be a witness to this future historic event of this millennium. The world has moved into the era of globalization with cutting edge technology and highly advanced therapies for some of the most complex human diseases. We can now identify the extremes of nano causes of illness and human diseases and intervene in the nano world. Putting intravascular stents, breaking down calcium plaques in the vessels, transplanting human hearts, utilizing artificial hearts, devices such as ICDs for life-threatening arrhythmias are just very few examples of incredibly advanced treatments for improving human health and treating illness. These highly advanced therapies that exist now were once only a dream of some crazy beings, decades and centuries ago. We have touched human lives in the most possible nano routes. We can fathom the DNA and RNA technology. We now have the vaccines for Covid-19 using the mRNA technology which is a huge technological advancement. Despite all of these, we have to remain that humble being since we still do not know a whole lot about lots of things. The fact that we are living in a world of a deadly pandemic despite persistent heroic measures worldwide from multiple sources for the past two years tells us that we are merely insignificant beings.
{"title":"An Unbounded Era of the Millennium","authors":"P. Bhattad","doi":"10.31254/jmr.2022.8201","DOIUrl":"https://doi.org/10.31254/jmr.2022.8201","url":null,"abstract":"Dear editor In this era of a modern pandemic of this new millennium, called as COVID-19, which has left no borders of the human world untouched on this planet. It is a timeless thing to be a witness to this future historic event of this millennium. The world has moved into the era of globalization with cutting edge technology and highly advanced therapies for some of the most complex human diseases. We can now identify the extremes of nano causes of illness and human diseases and intervene in the nano world. Putting intravascular stents, breaking down calcium plaques in the vessels, transplanting human hearts, utilizing artificial hearts, devices such as ICDs for life-threatening arrhythmias are just very few examples of incredibly advanced treatments for improving human health and treating illness. These highly advanced therapies that exist now were once only a dream of some crazy beings, decades and centuries ago. We have touched human lives in the most possible nano routes. We can fathom the DNA and RNA technology. We now have the vaccines for Covid-19 using the mRNA technology which is a huge technological advancement. Despite all of these, we have to remain that humble being since we still do not know a whole lot about lots of things. The fact that we are living in a world of a deadly pandemic despite persistent heroic measures worldwide from multiple sources for the past two years tells us that we are merely insignificant beings.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43382475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malignant peripheral nerve sheath tumor (MPNST) is an uncommon tumor. Here, we report a case of rectal MPNST. The patient was a 75 year old man with symptoms and signs of a mass protruded from anus. There was no evidence of neurofibromatosis type 1 in him or his family. Primary diagnosis was hemorrhoid. Biopsy was taken. The microscopic examination revealed spindle cells with large and hyperchromatic nuclei. Mitotic figures were numerous. Routine and ancillary techniques confirmed the diagnosis of MPNST. MPNST should be distinguished from more common lesions encountered at this anatomic site such as hemorrhoid, malignant melanoma, sarcomatoid carcinoma, and gastrointestinal stromal tumor.
{"title":"Malignant spindle cell tumor of the anal canal, what are the differential diagnoses?","authors":"F. Binesh, S. Shahcheraghi","doi":"10.31254/jmr.2022.8202","DOIUrl":"https://doi.org/10.31254/jmr.2022.8202","url":null,"abstract":"Malignant peripheral nerve sheath tumor (MPNST) is an uncommon tumor. Here, we report a case of rectal MPNST. The patient was a 75 year old man with symptoms and signs of a mass protruded from anus. There was no evidence of neurofibromatosis type 1 in him or his family. Primary diagnosis was hemorrhoid. Biopsy was taken. The microscopic examination revealed spindle cells with large and hyperchromatic nuclei. Mitotic figures were numerous. Routine and ancillary techniques confirmed the diagnosis of MPNST. MPNST should be distinguished from more common lesions encountered at this anatomic site such as hemorrhoid, malignant melanoma, sarcomatoid carcinoma, and gastrointestinal stromal tumor.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48207333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Ayatollahi, Mehran Jeyhaninejad, S. Mousavi, Mahdie Hamidfar, S. Shahcheraghi
Parasitic diseases are one of health problems in developing countries. In this study, the frequency of intestinal parasites in Alzahra laboratory of Isfahan province will be evaluated. This study was as descriptive and cross-sectional. A questionnaire was used in it. Finally, the collected data were entered into SPSS version 22 and then were analyzed. Of the 23874 fecal samples studied, 422 samples (1.7%) were positive and 23452 (98.3%) were negative. The highest number of referrals was related to summer. Giardia was the most common parasitic infection in spring, summer and autumn and Blastocystis hominis was the most common parasitic infection in winter. The infection of intestinal parasites should be considered and take more effective steps to increase the level of public and environmental health.
寄生虫病是发展中国家的健康问题之一。本研究将对伊斯法罕省Alzahra实验室肠道寄生虫的频率进行评估。本研究具有描述性和横断面性。研究采用问卷调查的方式。最后将收集到的数据输入到SPSS version 22中进行分析。在23874份粪便样本中，阳性422份(1.7%)，阴性23452份(98.3%)。转介人数最多的是夏季。春、夏、秋季以贾第鞭毛虫为主，冬季以人芽囊虫为主。应考虑肠道寄生虫的感染，并采取更有效的步骤，提高公共卫生和环境卫生水平。
{"title":"The frequency of intestinal parasites in the samples of Alzahra laboratory of Isfahan (2017-2019)","authors":"J. Ayatollahi, Mehran Jeyhaninejad, S. Mousavi, Mahdie Hamidfar, S. Shahcheraghi","doi":"10.31254/jmr.2022.8205","DOIUrl":"https://doi.org/10.31254/jmr.2022.8205","url":null,"abstract":"Parasitic diseases are one of health problems in developing countries. In this study, the frequency of intestinal parasites in Alzahra laboratory of Isfahan province will be evaluated. This study was as descriptive and cross-sectional. A questionnaire was used in it. Finally, the collected data were entered into SPSS version 22 and then were analyzed. Of the 23874 fecal samples studied, 422 samples (1.7%) were positive and 23452 (98.3%) were negative. The highest number of referrals was related to summer. Giardia was the most common parasitic infection in spring, summer and autumn and Blastocystis hominis was the most common parasitic infection in winter. The infection of intestinal parasites should be considered and take more effective steps to increase the level of public and environmental health.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45735493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Patil, Manojkumar Bhadake, Abhijit Acharya, G. Narwade
Introduction: Covid-19 pneumonia is heterogeneous disease with variable effect on lung parenchyma, airways and vasculature leading to long term effects on lung functions. Materials and methods: Multicentric, prospective, observational and interventional study included 1000 covid-19 cases confirmed with RT PCR. All cases were assessed with HRCT thorax, oxygen saturation, inflammatory marker as D-Dimer at entry point and follow up. Age, gender, Comorbidity and use BIPAP/NIV and outcome as with or without lung fibrosis were key observations. In selected cases, lower limb venous doppler and CT pulmonary angiography to rule out DVT or PTE. Statistical analysis is done by using Chi square test. Observations and analysis: Age (<50 and >50 years) and gender (male versus female) has significant association with D-Dimer level. [p<0.00001] & [p<0.010] respectively. CT severity score at entry point with D-Dimer level has significant correlation. [p<0.00001] D-Dimer level has significant association with duration of illness prior to hospitalization. [p<0.00001] Comorbidities have significant association with D-Dimer level. [p<0.00001] D-Dimer level has significant association with oxygen saturation. [p<0.00001] BIPAP/NIV requirement has significant association with D-Dimer level. [p<0.00001] Timing of BIPAP/NIV requirement during hospitalization has significant association with DDimer level. [p<0.00001] Follow-up D-Dimer titer during hospitalization as compared normal & abnormal to entry point level has significant association with post-covid lung fibrosis, deep vein thrombosis and pulmonary thromboembolism. [p<0.00001]. Conclusion: D-Dimer has documented very crucial role in covid-19 pneumonia in predicting severity of illness and assessing response to treatment during hospitalization and follow up titers have significant role in step-up or step-down interventions in critical care setting.
{"title":"Role of D-Dimer in Covid-19 pneumonia: sensitive marker of inflammation, predictor of mechanical ventilation, thromboembolic events and early marker of post covid-lung fibrosis; Prospective Multicentric, Observational, Interventional study in tertiary care setting in India","authors":"S. Patil, Manojkumar Bhadake, Abhijit Acharya, G. Narwade","doi":"10.31254/jmr.2022.8204","DOIUrl":"https://doi.org/10.31254/jmr.2022.8204","url":null,"abstract":"Introduction: Covid-19 pneumonia is heterogeneous disease with variable effect on lung parenchyma, airways and vasculature leading to long term effects on lung functions. Materials and methods: Multicentric, prospective, observational and interventional study included 1000 covid-19 cases confirmed with RT PCR. All cases were assessed with HRCT thorax, oxygen saturation, inflammatory marker as D-Dimer at entry point and follow up. Age, gender, Comorbidity and use BIPAP/NIV and outcome as with or without lung fibrosis were key observations. In selected cases, lower limb venous doppler and CT pulmonary angiography to rule out DVT or PTE. Statistical analysis is done by using Chi square test. Observations and analysis: Age (<50 and >50 years) and gender (male versus female) has significant association with D-Dimer level. [p<0.00001] & [p<0.010] respectively. CT severity score at entry point with D-Dimer level has significant correlation. [p<0.00001] D-Dimer level has significant association with duration of illness prior to hospitalization. [p<0.00001] Comorbidities have significant association with D-Dimer level. [p<0.00001] D-Dimer level has significant association with oxygen saturation. [p<0.00001] BIPAP/NIV requirement has significant association with D-Dimer level. [p<0.00001] Timing of BIPAP/NIV requirement during hospitalization has significant association with DDimer level. [p<0.00001] Follow-up D-Dimer titer during hospitalization as compared normal & abnormal to entry point level has significant association with post-covid lung fibrosis, deep vein thrombosis and pulmonary thromboembolism. [p<0.00001]. Conclusion: D-Dimer has documented very crucial role in covid-19 pneumonia in predicting severity of illness and assessing response to treatment during hospitalization and follow up titers have significant role in step-up or step-down interventions in critical care setting.","PeriodicalId":50132,"journal":{"name":"Journal of Medical Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49168315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Binesh, M. Mortazavizadeh, R. N. Moghadam, S. Shahcheraghi
Castleman's disease is an uncommon, lymphoproliferative disease. Its etiology is unknown. Spine involvement is very scant in Castleman's disease. The authors report on the case of a 50 year-old man who referred with saddle anesthesia and low back pain from 2.5 years ago. A CT scan showed an extra medullary mass at S1-S2 level of the spinal canal without bone involvement. The signal specs on MRI were resembling to signal of neurofibroma .The patient underwent needle biopsy. Histological examination confirmed the diagnosis of Castleman disease, hyaline-vascular type. He received rituximab and pain was dramatically relieved. Although rare, Castleman disease should be considered in the differential diagnosis of an extramedullary mass.
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