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Correlation between Serum Homocysteine Level and Cystatin C Elevation in Patients with H-type Hypertension h型高血压患者血清同型半胱氨酸水平与胱抑素C升高的相关性
Pub Date : 2022-06-30 DOI: 10.6913/mrhk.040207
P. Xiao, Kai-Huang Chen, Y. Zhu
[Objective] To investigate the correlation between serum levels of homocysteine (Hcy) and cystatin C (CysC), a sensitive marker of renal function, in patients with H-type hypertension. [Methods] A total of 857 patients with essential hypertension without moderate to severe renal impairment (estimated glomerular filtration rate ≥ 60 ml/(min-1.73 m2) by Modification of Diet in Renal Disease equation) visited the Seventh Affiliated Hospital of Sun Yat-sen University from May 2018 to May 2020 were selected as the research subjects. The observation group (n = 635) consisted of patients with H-type hypertension (essential hypertension with Hcy ≥ 10 mmol/l) and the control group (n = 222) consisted of patients with non-H-type hypertension (essential hypertension with Hcy < 10 mmol/l). Multivariate logistic regression analysis, curve fitting, and threshold analysis were used to evaluate the correlation between elevated CysC and serum Hcy levels. [Results]CysC in observation group was significantly higher than that in control group (0.96 ± 0.160 vs 0.84 ± 0.13 mmol/l; p < 0.001). Multivariate logistic regression analysis, curve fitting, and threshold analysis showed that there was a significant difference in the risk of CysC elevation between Hcy levels at 10-25 mmol/L and Hcy levels below 10 mmol/L; there was no significant difference in the risk of CysC elevation between Hcy levels above 25 mmol/L and Hcy levels below 10 mmol/L. The inflection point of Hcy was 15.23 mmol/L, and when Hcy was < 15.23 mmol/L, the probability of CysC elevation increased by 27% for each 1 mmol/L increase in Hcy (OR 1.27, 95% Cl: 1.12, 1.44; P = 0.0002). When Hcy was > 15.23 mmol/l, the probability of CysC elevation was reduced by 4% for each 1 mmol/l increase in Hcy (OR 0.96, 95% Cl: 0.92, 1.01; P = 0.1085). [Conclusions] The risk of CysC in patients with H-type hypertension is higher than that in patients with non-H-type hypertension when Hcy is between 10-25 mmol/L; and the probability of cystatin C elevation is the highest when Hcy is at 15.23 mmol/L.
[目的]探讨h型高血压患者血清同型半胱氨酸(Hcy)水平与肾功能敏感指标胱抑素C (CysC)的相关性。【方法】选取2018年5月至2020年5月中山大学附属第七医院就诊的857例无中重度肾功能损害(肾小球滤过率≥60 ml/(min-1.73 m2),采用肾脏疾病方程修正饮食法)的原发性高血压患者作为研究对象。观察组(n = 635)为h型高血压(Hcy≥10 mmol/l的原发性高血压)患者,对照组(n = 222)为非h型高血压(Hcy < 10 mmol/l的原发性高血压)患者。采用多因素logistic回归分析、曲线拟合和阈值分析评价CysC升高与血清Hcy水平的相关性。[结果]观察组CysC显著高于对照组(0.96±0.160 vs 0.84±0.13 mmol/l;P < 0.001)。多因素logistic回归分析、曲线拟合和阈值分析显示,Hcy水平在10 ~ 25 mmol/L和低于10 mmol/L时,CysC升高的风险有显著性差异;在Hcy水平高于25 mmol/L和低于10 mmol/L之间,CysC升高的风险无显著差异。Hcy的拐点为15.23 mmol/L,当Hcy < 15.23 mmol/L时,Hcy每升高1 mmol/L, CysC升高的概率增加27% (OR 1.27, 95% Cl: 1.12, 1.44;P = 0.0002)。当Hcy > 15.23 mmol/l时,Hcy每升高1 mmol/l, CysC升高的概率降低4% (OR 0.96, 95% Cl: 0.92, 1.01;P = 0.1085)。[结论]Hcy在10 ~ 25 mmol/L之间时,h型高血压患者发生CysC的风险高于非h型高血压患者;当Hcy为15.23 mmol/L时,胱抑素C升高的概率最高。
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引用次数: 0
Research Progression of Colposcopy Image-assisted Diagnosis Based on Deep Learning 基于深度学习的阴道镜图像辅助诊断研究进展
Pub Date : 2022-06-30 DOI: 10.6913/mrhk.040202
Yehong Huang
Cervical cancer is one of the most common malignant tumors in women; hence the world has been working to improve the effective screening and prevention of cervical cancer. Colposcopy plays a central role in cervical cancer prevention, but its accuracy and reproducibility are still limited. The use of deep learning in the field of medical images allows more researchers as well as to explore the application of deep learning in colposcopy image-assisted diagnosis. In this paper, we summarize the research status of this field and propose the current shortcomings and improvement directions this research field.
宫颈癌是女性中最常见的恶性肿瘤之一;因此,全世界一直在努力提高宫颈癌的有效筛查和预防。阴道镜检查在宫颈癌预防中起着核心作用,但其准确性和可重复性仍然有限。深度学习在医学图像领域的应用,可以让更多的研究者探索深度学习在阴道镜图像辅助诊断中的应用。本文总结了该领域的研究现状,提出了该研究领域目前存在的不足和改进方向。
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引用次数: 0
Factors Affecting the Accuracy of Coding Selection of Major Diagnoses on the Homepage of Medical Records 影响病案首页重大诊断编码选择准确性的因素
Pub Date : 2022-06-30 DOI: 10.6913/mrhk.040209
X. Ye, Li Ma, Yutao Qiu, Jipeng Yang
[Objective] This study aimed to investigate current issues, root causes, and improvement measures of the main diagnostic codes on the homepage of a hospital's inpatient medical records, and to improve the accuracy of the hospital's main diagnostic codes.[Methods]A retrospective analysis was carried out on the homepage data of inpatient medical records in a hospital. After implementing the quality control of medical record coding, we compared and analyzed 1000 medical records before the intervention (March 1 to June 30, 2020) and 1000 medical records after the intervention (March 1 to June 30, 2021). The accuracy of the homepage data of the medical records was compared and the quality control efficacy after the intervention was evaluated.[Results] Following the intervention, the number of major diagnostic errors on the homepage of medical records decreased by 84% (from 38 cases per 1000 to 6 cases per 1000, p<0.05). Among them, the main diagnosis error was reduced from 6 cases to 1 case, the main diagnosis selection error was reduced from 5 cases to 2 cases, the ambiguous (QY) medical records were reduced from 19 cases to 2 cases, and the medical records with codes not merged were reduced from 9 cases to 1 case. According to the analysis of influencing factors, after the intervention measures were taken, the filling errors by physicians decreased from 17 cases to 2 cases, the errors by coders decreased from 12 cases to 2 cases, and the errors from information management decreased from 9 cases to 2 cases.[Conclusions] After the intervention, the number of errors in filling by physicians, coding by coders, and information management on the homepage of medical records decreased significantly. In addition, the accuracy of the main diagnostic codes on the homepage has been greatly improved, which helps ensure the reliability of information statistics and effectively improves the quality and safety of medical care.
【目的】了解某医院住院病案首页主要诊断码存在的问题、原因及改进措施,提高医院主要诊断码的准确性。[方法]对某医院住院病案主页资料进行回顾性分析。在实施病案编码质量控制后,对干预前(2020年3月1日至6月30日)的1000份病案与干预后(2021年3月1日至6月30日)的1000份病案进行对比分析。比较病案首页数据的准确性,评价干预后的质量控制效果。[结果]干预后,病案首页重大诊断错误数量下降了84%(由38 / 1000下降到6 / 1000,p<0.05)。其中,主要诊断错误从6例减少到1例,主要诊断选择错误从5例减少到2例,模棱两可(QY)病历从19例减少到2例,未合并代码的病历从9例减少到1例。通过对影响因素的分析,采取干预措施后,医生差错从17例减少到2例,编码员差错从12例减少到2例,信息管理差错从9例减少到2例。[结论]干预后,医师填写错误、编码员编码错误、病案首页信息管理错误明显减少。此外,主页上主要诊断代码的准确性也大大提高,有助于保证信息统计的可靠性,有效提高医疗质量和安全性。
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引用次数: 0
A Survey on Junior Nurses’ Risk Perception Level and Its Influencing Factors 初级护士风险感知水平及其影响因素调查
Pub Date : 2022-06-30 DOI: 10.6913/mrhk.040203
Lei Peng, Ling Jin, Xin-Li Ma
[Objective] Junior nurses’ perceived risk level may affect their career satisfaction and performances. This study sought to investigate the current situation of risk perception level of junior nurses with undergraduate degrees and to determine its influencing factors, with the aim to provide a reference for nursing managers to carry out targeted training and education for junior nurses. [Methods] A total of 484 junior nurses with undergraduate degrees from five tertiary hospitals in Guangdong Province were selected by the convenience sampling method as the research participants. The general information questionnaire, risk perception questionnaire and the Chinese version of the Positive and Negative Affect Schedule (PANAS) scale were used for the survey. [Results] The enrolled junior nurses scored 85.84±13.56 (Full score was 100) on the risk perception survey. Working years, positive and negative affect, gender, and personality characteristics were the main influencing factors for junior nurses’ risk perception levels (P<0.05). [Conclusions] Junior nurses' risk perception was at a moderate and acceptable level. However, their risk perception was higher in dimensions such as physical function, occupational exposure, and time. Therefore, nursing managers should pay attention to high-risk perception items, and targeted measures should be taken according to different characteristics of nurses to improve their ability to correctly recognize risks and eliminate negative emotions in order to improve the quality of nursing services.
[目的]初级护士感知风险水平对其职业满意度和绩效的影响。本研究旨在调查本科初级护士风险感知水平的现状,并确定其影响因素,为护理管理者对初级护士进行有针对性的培训教育提供参考。[方法]采用方便抽样法,抽取广东省5家三级医院本科以上初级护士484名作为研究对象。采用一般信息问卷、风险感知问卷和中文版的积极与消极影响量表(PANAS)进行调查。[结果]入组初级护士风险感知调查得分为85.84±13.56分(满分为100分)。工作年限、积极情绪与消极情绪、性别、人格特征是影响初级护士风险感知水平的主要因素(P<0.05)。[结论]初级护士的风险认知处于中等可接受水平。然而,他们在身体机能、职业暴露和时间等维度上的风险感知更高。因此,护理管理者应重视高危感知项目,并根据护士的不同特点,有针对性地采取措施,提高护士正确识别风险、消除负面情绪的能力,以提高护理服务质量。
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引用次数: 0
Correlates of Traditional Chinese Medicine Syndrome Types in Polycystic Ovary Syndrome 多囊卵巢综合征中医证型的相关性研究
Pub Date : 2022-06-30 DOI: 10.6913/mrhk.040204
Tingwei Wang, Jie Zhong, L. Zong
[Objective] Polycystic ovary syndrome (PCOS), a common female health condition caused by a hormonal imbalance due to the ovaries producing excess male hormones, is also considered a chronic endocrine-metabolic syndrome. According to the traditional Chinese medicine (TCM) theory, multiple factors including insufficiency of kidney and liver as well as phlegm dampness may result in PCOS. This study aimed to investigate the distribution pattern of TCM syndrome types in patients with PCOS, and to determine the glucose metabolism status among these patients. [Methods] A total of 60 patients diagnosed with PCOS in our center were enrolled in this study. These patients were classified into three groups based on their TCM syndrome types, including phlegm dampness syndrome, liver stagnation syndrome, and kidney insufficiency syndrome. A uniformly formulated basic information sheet was collected, and all of them underwent glucose tolerance test (OGTT). The correlations of body mass index (BMI), waist to hip ratio (WHR), and glucose metabolism in patients with different syndromes were compared. [Results] The patients with phlegm dampness syndrome type (n=32) were the most among these 60 patients with PCOS, accounting for 53.33%, followed by liver stagnation syndrome (n=18; 30%) and kidney insufficiency syndrome (n=10; 16.67%). The BMI and WHR of patients with phlegm dampness syndrome were higher than those with liver stagnation syndrome and kidney insufficiency syndrome (P<0.01). There was no significant difference in the incidence of abnormal glucose metabolism (IFG/IGT/diabetes) among the three groups (P>0.05). [Conclusions] The main TCM syndrome type in patients with PCOS is phlegm dampness syndrome, which was linked to obesity and abdominal obesity.
【目的】多囊卵巢综合征(PCOS)被认为是一种慢性内分泌代谢综合征,是由于卵巢分泌过多的雄性激素而导致的激素失衡,是一种常见的女性健康状况。根据中医理论,多囊卵巢综合征可能由肝肾功能不全、痰湿等多种因素引起。本研究旨在探讨PCOS患者中医证型的分布规律,了解PCOS患者的糖代谢状况。【方法】本研究共纳入60例经诊断为PCOS的患者。根据中医证型将患者分为痰湿证、肝郁证、肾虚证3组。收集统一制定的基本信息表,并进行葡萄糖耐量试验(OGTT)。比较不同综合征患者的身体质量指数(BMI)、腰臀比(WHR)和糖代谢的相关性。[结果]60例PCOS患者中痰湿证型最多(n=32),占53.33%,其次为肝郁证(n=18);30%)和肾功能不全综合征(n=10;16.67%)。痰湿证的BMI和WHR高于肝郁证和肾虚证(P0.05)。【结论】PCOS患者中医证型以痰湿证为主,与肥胖、腹型肥胖相关。
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引用次数: 0
Prevalence and Etiologies of Dyspnea in Adults at the General Hospital of Douala, Cameroon 喀麦隆杜阿拉总医院成人呼吸困难的患病率和病因分析
Pub Date : 2022-06-25 DOI: 10.31254/jmr.2022.8305
Claire Françoise Bitchong Ekono, Thérèse Azoumbou Mefant, Ange-Fidèle Moadoume Nanga, H. B. M. Ngahane
Introduction: Dyspnea is a subjective feeling of discomfort. It can be acute or chronic onset. Our objective was to determine the frequency and etiologies of dyspnea in adults at the medical and surgical emergencies of the Douala General Hospital. Methods: This was a retrospective study conducted from January 1, 2018 to February 28, 2020. Patients over the age of 18 who came to consult for dyspnea were enrolled. Sociodemographic and clinical data were collected and analyzed using SPSS version 25 software. Results: Of the 565 files collected, 55.93% were women. The mean age was 47.66 ± 17.87 years. The frequency of dyspnea was 4.18%. Married people represented 53.63% of the workforce. History of high blood pressure (39.14%), chronic kidney disease (26.70%) and HIV infection (12.21%) were the most common. Acute dyspnea accounted for 89.56% of cases. The etiologies were dominated by: cardiovascular conditions (24.43%), non-tumor bronchopulmonary and pleural pathologies (20.88%), tumoral conditions (10.27%). The most common cardiac and pulmonary causes were acute pulmonary edema (78.26%), lower respiratory infections (52.54%) and exacerbations of asthma (23.73%). Conclusion: Dyspnea represents 4.18% of admissions to the medicosurgical emergency department of the Douala General Hospital. Etiologies are dominated by cardiac and lower respiratory causes.
引言:呼吸困难是一种主观的不适感。它可以是急性发作,也可以是慢性发作。我们的目的是确定杜阿拉综合医院急诊科成人呼吸困难的频率和病因。方法:这是一项从2018年1月1日至2020年2月28日进行的回顾性研究。18岁以上因呼吸困难前来就诊的患者被纳入研究。使用SPSS 25版软件收集和分析社会形态和临床数据。结果:在收集的565份档案中,55.93%为女性。平均年龄47.66±17.87岁。呼吸困难的发生率为4.18%,已婚者占劳动力的53.63%。高血压史(39.14%)、慢性肾脏病史(26.70%)和艾滋病毒感染史(12.21%)最为常见。急性呼吸困难占89.56%。病因主要有:心血管疾病(24.43%)、非肿瘤性支气管肺和胸膜疾病(20.88%)、肿瘤疾病(10.27%)。最常见的心肺原因是急性肺水肿(78.26%),下呼吸道感染(52.54%)和哮喘加重(23.73%)。结论:呼吸困难占杜阿拉综合医院内科急诊的4.18%。病因主要是心脏和下呼吸道原因。
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引用次数: 0
The Long and Short of COVID-19 新冠肺炎的长短
Pub Date : 2022-06-25 DOI: 10.31254/jmr.2022.8301
Hemant Mehta, P. Swapna, P. Jiandani, V. Nagvekar, G. Soni
COVID-19 illness is self-limiting illness in majority of patients, but some patients continue to have or develop new medical issues four weeks after suffering from the infection (proven or presumed), and have been labelled as Long Covid, which depicts the consequences of COVID-19.The duration of Long Covid beyond 4 weeks is unknown. We are reporting a case of a young female who presented with encephalopathy which was due to asymptomatic COVID-19 infection suffered in the past. Could this be a Long Covid syndrome? How was the diagnosis of Covid encephalopathy suspected and investigated, with its treatment and review of relevant literature is described
新冠肺炎疾病在大多数患者中是自限性疾病,但一些患者在感染(已证实或推测)四周后继续出现或出现新的医疗问题,并被标记为Long新冠肺炎,描述了COVID-19的后果。Long新冠肺炎持续时间超过4周尚不清楚。我们报告了一例年轻女性出现脑病的病例,这是由于过去无症状的新冠肺炎感染所致。这可能是长期新冠肺炎综合征吗?对新冠肺炎脑病的诊断、治疗和相关文献的回顾进行了描述
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引用次数: 0
Evaluation of epidemiological and clinical characteristics of pulmonary tuberculosis in elderly patients of Yazd city 亚兹德市老年肺结核流行病学及临床特征分析
Pub Date : 2022-06-25 DOI: 10.31254/jmr.2022.8306
J. Ayatollahi, H. Mozafari, S. Mousavi, Mahdie Hamidfar, S. Shahcheraghi
Due to the fact that tuberculosis is one of the most important diseases in Iran and also due to the re-emergence of tuberculosis in the world, this disease has received more attention. This study was aimed to investigate epidemiological and clinical characteristics of pulmonary tuberculosis in elderly patients of Yazd city. After the laboratory diagnosis, the doctor visited the patients and after confirming the diagnosis, the patients were referred to a specialist to complete the file and receive anti-tuberculosis drugs. Necessary information including: history, history of risk factors, history of treatment, diagnostic radiography, drug resistance and results of pulmonary tuberculosis treatment were reviewed by referring to patients' files. Finally, statistical analysis was performed using SPSS (version 16). Most of the participants were 75 years old. Most of the participants were illiterate and housewives. Nearly 59% had no underlying disease. Diabetes was the most common underlying disease among individuals. The results showed that knowledge of personal health care was lower in people with lower levels of literacy, which further increases the incidence of this disease in this group.
由于结核病是伊朗最重要的疾病之一,也由于结核病在世界范围内的再次出现,这种疾病受到了更多的关注。本研究旨在调查亚兹德市老年患者肺结核的流行病学和临床特征。实验室诊断后,医生对患者进行了检查,确认诊断后,将患者转诊至专家处,完成档案并接受抗结核药物治疗。通过查阅患者档案,回顾必要的信息,包括:病史、危险因素史、治疗史、诊断性放射学、耐药性和肺结核治疗结果。最后,使用SPSS(16版)进行统计分析。大多数参与者都是75岁。大多数参与者是文盲和家庭主妇。近59%的患者没有潜在疾病。糖尿病是个体中最常见的潜在疾病。结果表明,识字水平较低的人对个人医疗保健的了解程度较低,这进一步增加了这一群体中这种疾病的发病率。
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引用次数: 0
Albumin, WBC, RBC, Hemoglobin, Platelet, MCV and MCH levels in COVID-19 patients with Mucormycosis opportunistic infection 新冠肺炎毛霉菌病机会性感染患者的白蛋白、白细胞、红细胞、血红蛋白、血小板、MCV和MCH水平
Pub Date : 2022-06-25 DOI: 10.31254/jmr.2022.8308
S. Shahcheraghi, Mahdie Hamidfar, Faezeh Heidari, Sajjad Shahmohammadi, S. Mousavi, Tahereh Fallah, Y. Yazdani
The coronavirus disease 19 (COVID-19) is a profoundly communicable and pathogenic viral disease brought about by intense respiratory disorder coronavirus 2, which made worldwide pandemic that drove a sensational loss of human existence around the world. Recently, instances of mucormycosis have been described in patients with Coronavirus. Routine laboratory tests especially biochemical and hematological are vital tests in terms of both finding and seriousness of Coronavirus. This study was intended to evaluate albumin, WBC, RBC, hemoglobin, platelet, MCV and MCH levels in COVID-19 patients suffering from mucormycosis. During this study, hospitalized COVID-19 patients with mucormycosis were investigated. Gender, age, hospitalization and recovery were patients recorded information. The laboratory parameters included albumin, WBC, RBC, hemoglobin, platelet, MCV and MCH levels. Finally, data was analyzed by SPSS. At present study, there was no significant difference between albumin, WBC, RBC, hemoglobin, platelet, MCV and MCH levels in COVID-19 patients suffering from mucormycosis levels based on gender, age, hospitalization and recovery parameters. According to results, it is essential to do more researches with a larger scale based on more parameters in patients with mucormycosis.
新型冠状病毒病(COVID-19)是由重症呼吸系统疾病冠状病毒2引起的一种具有高度传染性和致病性的病毒性疾病,在全球范围内造成了巨大的人类生存损失。最近,在冠状病毒患者中出现了毛霉病的病例。常规实验室检查,特别是生化和血液学检查,对于发现和严重程度都是至关重要的。本研究旨在评估新冠肺炎毛霉菌病患者的白蛋白、白细胞、红细胞、血红蛋白、血小板、MCV和MCH水平。在本研究中,对住院的COVID-19毛霉病患者进行调查。记录患者的性别、年龄、住院情况及康复情况。实验室参数包括白蛋白、白细胞、红细胞、血红蛋白、血小板、MCV和MCH水平。最后用SPSS软件对数据进行分析。在本研究中,不同性别、年龄、住院及康复参数的COVID-19毛霉菌病患者白蛋白、白细胞、红细胞、血红蛋白、血小板、MCV和MCH水平无显著差异。由此可见,在毛霉病患者中开展更多、更大规模、更多参数的研究是必要的。
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引用次数: 0
Evaluation of Ca++, Na+, Mg2+, K+ and P levels in the 2019 novel coronavirus patients with mucormycosis 2019年新型冠状病毒感染毛霉病患者Ca++、Na+、Mg2+、K+和P水平的评价
Pub Date : 2022-06-25 DOI: 10.31254/jmr.2022.8304
Mahdie Hamidfar, S. Shahcheraghi, Faezeh Heidari, Sajjad Shahmohammadi, J. Ayatollahi, Tahereh Fallah, Y. Yazdani, Mansoureh Mirhosaini
The new coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is a risk factor for universal public health difficulties. Some COVID-19 patients have an increased risk of fungal infections particularly mucormycosis diseases. Current laboratory examinations especially mineral elements are very important tests in terms of both detection and severity of COVID-19. The aim of the present study was to evaluate Ca++, Na+ , Mg2+, K+ and P levels in the COVID-19 patients with mucormycosis. This study was done during 2021- 2022. All hospitalized COVID-19 (PCR positive test) patients with mucormycosis participated in the present study. Data included gender, age, hospitalization and recovery. The tested laboratory parameters included Ca++, Na+ , Mg2+, K+ and P rate. Finally, SPSS software analyzed the data. The results revealed that there was a statistically significant difference between the two groups admitted to the ward and ICU in terms of K+ . There was also a significant difference between recovery and K+ level. There was no significant difference in Ca++, Na+ , Mg2+ and P in terms of gender, age, hospitalization and recovery. According to the findings, K+ level should be checked as a key element in the COVID-19 patients with mucormycosis.
由SARS-CoV-2引起的2019新型冠状病毒疾病(新冠肺炎)是普遍公共卫生困难的风险因素。一些新冠肺炎患者感染真菌的风险增加,尤其是毛霉菌病。就新冠肺炎的检测和严重程度而言,目前的实验室检查,尤其是矿物元素,是非常重要的检测。本研究的目的是评估新冠肺炎毛霉菌病患者的Ca++、Na+、Mg2+、K+和P水平。这项研究是在2021年至2022年期间进行的。所有新冠肺炎(PCR阳性检测)毛霉菌病住院患者都参与了本研究。数据包括性别、年龄、住院和康复情况。实验室测试的参数包括Ca++、Na+、Mg2+、K+和磷含量。最后,运用SPSS软件对数据进行分析。结果显示,入住病房和ICU的两组患者在K+方面存在统计学显著差异。恢复和K+水平之间也存在显著差异。Ca++、Na+、Mg2+和P在性别、年龄、住院和康复方面没有显著差异。根据研究结果,应将K+水平作为新冠肺炎毛霉菌病患者的关键因素进行检查。
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引用次数: 0
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