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Tensor power flow formulations for multidimensional analyses in distribution systems 用于配电系统多维分析的张量功率流公式
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-19 DOI: 10.1016/j.ijepes.2024.110275
Edgar Mauricio Salazar Duque , Juan S. Giraldo , Pedro P. Vergara , Phuong H. Nguyen , Han (J.G.) Slootweg
In this paper, we present two multidimensional power flow formulations based on a fixed-point iteration (FPI) algorithm to efficiently solve hundreds of thousands of Power flows (PFs) in distribution systems. The presented algorithms are the base for a new TensorPowerFlow (TPF) tool and shine for their simplicity, benefiting from multicore Central processing unit (CPU) and Graphics processing unit (GPU) parallelization. We also focus on the mathematical convergence properties of the algorithm, showing that its unique solution is at the practical operational point. The proof is validated using numerical simulations showing the robustness of the FPI algorithm compared to the classical Newton–Raphson (NR) approach. In the case study, a benchmark with different PF solution methods is performed, showing that for applications requiring a yearly simulation at 1-minute resolution, the computation time is decreased by a factor of 164, compared to the NR in its sparse formulation. Finally, a set of applications is described, highlighting the potential of the proposed formulations over a wide range of analyses in distribution systems.
在本文中,我们介绍了基于定点迭代(FPI)算法的两种多维电力流公式,可有效解决配电系统中成千上万的电力流(PF)问题。所提出的算法是新的 TensorPowerFlow(TPF)工具的基础,因其简便性而大放异彩,并受益于多核中央处理器(CPU)和图形处理器(GPU)并行化。我们还重点研究了该算法的数学收敛特性,表明其唯一解处于实际操作点。通过数值模拟验证了这一证明,与经典的牛顿-拉斐森(NR)方法相比,FPI 算法具有很强的鲁棒性。在案例研究中,使用不同的 PF 求解方法进行了基准测试,结果表明,对于需要每年以 1 分钟分辨率进行模拟的应用,计算时间比稀疏表述的 NR 缩短了 164 倍。最后,介绍了一系列应用,突出了所提公式在配电系统各种分析中的潜力。
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引用次数: 0
Enhanced frequency aware microgrid scheduling towards seamless islanding under frequency support of heterogeneous resources: A distributionally robust chance constrained approach 增强频率感知微电网调度,实现异构资源频率支持下的无缝孤岛:分布稳健的机会约束方法
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-19 DOI: 10.1016/j.ijepes.2024.110310
Danyang Xu, Zhigang Wu
This paper introduces an enhanced frequency aware microgrid scheduling (E-FAMS) model designed to achieve seamless islanding (SI) for microgrids after experiencing an unintentional islanding event (UIE). The model addresses uncertainties in load forecasting and demand-side resources’ (DSRs) frequency support, described using a Wasserstein-metric ambiguity set, through the distributionally robust chance constrained (DRCC) approach. It concurrently optimizes unit commitment, generation dispatch, reserve capacity, power exchange, and the frequency response of heterogeneous frequency support resources (HFSRs). A quadratic frequency (QF) approach is proposed to derive sufficient conditions for the maximum frequency deviation (MFD) constraints, which are then convexified using the piecewise linear of multivariable functions (PWL-MFs) technique and integrated into the proposed model. Case study results confirm the effectiveness of the proposed model, providing a novel solution for SI in microgrids.
本文介绍了一种增强型频率感知微电网调度(E-FAMS)模型,旨在实现微电网在经历无意孤岛事件(UIE)后的无缝孤岛(SI)。该模型通过分布式稳健机会约束(DRCC)方法,解决了负荷预测和需求侧资源(DSR)频率支持中的不确定性问题,这些不确定性使用瓦瑟斯坦计量模糊集进行描述。该方法可同时优化机组承诺、发电调度、储备容量、电力交换以及异构频率支持资源(HFSR)的频率响应。提出了一种二次频率(QF)方法来推导最大频率偏差(MFD)约束的充分条件,然后使用多变量函数的分片线性(PWL-MFs)技术对其进行凸化,并将其集成到所提出的模型中。案例研究结果证实了所提模型的有效性,为微电网中的 SI 提供了一种新的解决方案。
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引用次数: 0
Development of coordinated control method based on Graph search method between EV and DG for voltage regulation 开发基于图谱搜索法的电动汽车与 DG 电压调节协调控制方法
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-19 DOI: 10.1016/j.ijepes.2024.110295
Jisoo Kim, Jean Mahseredjian
In this paper, a study is conducted to solve voltage problems that may occur, when large-scale Distributed Generations (DGs) and Electric Vehicles (EVs) are connected to the distribution system, through coordinated control between DGs and EVs. Using the Graph Search Method (GSM), the voltage problem was solved through the reactive power control of EVs and DGs in the near area where the voltage problem occurred. As a result, it was possible to obtain a result with high robustness against the change of the topology and reduction of the total loss of distribution system. In addition, when the voltage problem cannot be solved by only reactive power control, the active power control was performed for EVs and DGs included in a specific divided system of the conventional distribution system using the GSM to maintain the voltage within the normal range. Finally, to verify the performance of the proposed method, the whole algorithm was implemented by linking the Open Source Distribution System Simulator (OpenDSS), and the MATLAB.
本文研究了当大规模分布式发电(DGs)和电动汽车(EVs)接入配电系统时,通过 DGs 和 EVs 之间的协调控制来解决可能出现的电压问题。利用图搜索法(GSM),通过对发生电压问题的附近区域的电动汽车和分布式发电设备进行无功功率控制,解决了电压问题。因此,可以获得对拓扑变化具有较高鲁棒性的结果,并减少了配电系统的总损耗。此外,当电压问题无法仅通过无功功率控制来解决时,还利用 GSM 对传统配电系统的特定划分系统中包含的电动汽车和 DG 进行了有功功率控制,以将电压维持在正常范围内。最后,为了验证所提方法的性能,通过连接开源配电系统仿真器(OpenDSS)和 MATLAB 实现了整个算法。
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引用次数: 0
Incorporating adaptive local search and experience-based perturbed learning into artificial rabbits optimizer for improved DC motor speed regulation 将自适应局部搜索和基于经验的扰动学习纳入人工兔子优化器,改善直流电机调速性能
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-19 DOI: 10.1016/j.ijepes.2024.110266
Rizk M. Rizk-Allah , Davut Izci , Serdar Ekinci , Ali Diabat , Absalom E. Ezugwu , Laith Abualigah
The widespread utilization of direct current (DC) motors in real-life engineering applications has led to the need for precise speed control, making controllers a crucial aspect of DC motor systems. Proportional-integral-derivative (PID) controllers have been widely adopted due to their simplicity and effectiveness. However, recent advancements have introduced fractional order PID (FOPID) controllers that offer improved control performance for complex systems with nonlinear dynamics. To fully leverage FOPID controller’s benefits, an efficient tuning method is essential. In this study, we propose artificial rabbits optimization (ARO) algorithm with enhanced strategies, called IARO, to optimize the FOPID controller for DC motor speed regulation. The IARO algorithm incorporates an adaptive local search (ALS) mechanism and an experience-based perturbed learning (EPL) strategy, addressing the shortcomings of ARO and providing better exploration–exploitation balance. We validate the superiority of IARO over competitive algorithms on the CEC2020 benchmark functions, showcasing improved solution stability and consistency. The IARO algorithm is then applied to tune the FOPID controller for DC motor speed regulation. The problem is formulated as a constraint minimization task, optimizing the integral of time-weighted absolute error cost function while adhering to critical design requirements. Comparative simulations demonstrate the IARO algorithm’s ability to achieve superior cost function values and faster convergence compared to other algorithms' based FOPID controllers. The IARO-based FOPID controller exhibits enhanced stability, smoother speed response, larger gain margin, and wider bandwidth compared to other reported algorithms. Additionally, a hardware implementation is also conducted to further validate the practical applicability of IARO based design method. The IARO-based FOPID controller showed remarkable accuracy in tracking multi-step reference inputs and robustly rejected external disturbances, outperforming other recent optimization-based controllers. Additionally, the IARO-based PID controller achieved better performance in key time-domain metrics, including lower overshoot, faster rise time, shorter settling time, and minimized peak time.
直流(DC)电机在实际工程应用中的广泛使用导致了对精确速度控制的需求,从而使控制器成为直流电机系统的一个重要方面。比例积分派生(PID)控制器因其简单有效而被广泛采用。然而,最近的发展引入了分数阶 PID(FOPID)控制器,为具有非线性动态特性的复杂系统提供了更好的控制性能。要充分发挥 FOPID 控制器的优势,高效的调节方法必不可少。在本研究中,我们提出了具有增强策略的人工兔子优化(ARO)算法,称为 IARO,用于优化直流电机调速的 FOPID 控制器。IARO 算法结合了自适应局部搜索(ALS)机制和基于经验的扰动学习(EPL)策略,解决了 ARO 算法的不足,并提供了更好的探索-开发平衡。我们在 CEC2020 基准函数上验证了 IARO 相对于竞争算法的优越性,展示了解决方案稳定性和一致性的提高。然后,我们将 IARO 算法应用于调整直流电机速度调节的 FOPID 控制器。该问题被表述为一个约束最小化任务,在遵守关键设计要求的同时优化时间加权绝对误差成本函数的积分。比较仿真证明,与其他基于算法的 FOPID 控制器相比,IARO 算法能够获得更优越的成本函数值和更快的收敛速度。与其他已报道的算法相比,基于 IARO 的 FOPID 控制器具有更高的稳定性、更平滑的速度响应、更大的增益余量和更宽的带宽。此外,为了进一步验证基于 IARO 的设计方法的实用性,还进行了硬件实施。基于 IARO 的 FOPID 控制器在跟踪多步参考输入方面表现出了卓越的准确性,并能稳健地拒绝外部干扰,优于其他最新的基于优化的控制器。此外,基于 IARO 的 PID 控制器在关键时域指标方面也取得了更好的性能,包括更低的过冲、更快的上升时间、更短的平稳时间和最小化的峰值时间。
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引用次数: 0
Towards non-virtual inertia control of renewable energy for frequency regulation: Modeling, analysis and new control scheme 为频率调节实现可再生能源的非虚拟惯性控制:建模、分析和新控制方案
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-17 DOI: 10.1016/j.ijepes.2024.110314
Haishu Gao , Feng Zhang , Lei Ding , Gang Zhang , Libin Yang , Athuman Salimu
Currently, when renewable generation participates in frequency regulation, the traditional control method is to emulate synchronous generators through virtual inertia control. However, virtual inertia has a time delay, so essentially, it is a fast power response. Meanwhile, virtual inertia control is likely to be affected by frequency fluctuation since it responds to the derivative of frequency. Hence, it’s worth exploring non-virtual inertia control for renewable energy when participating in frequency regulation. For this reason, a novel two-segment droop control scheme for renewable energy frequency regulation is proposed in this research. Firstly, the extended system frequency regulation (SFR) model, which contains virtual inertia with time delay, is built and analytically solved by order decrement based on the Routh approximation method. Afterwards, according to the analytical solution, time delay affects the frequency response of renewable energy. It can also be analytically proved that the non-virtual inertia control, e.g., sole droop control, could replace virtual inertia under the same frequency deviation. Still, more energy may be needed for frequency regulation. Furthermore, a novel two-segment droop control is presented, and to analytically prove its ability to replace virtual inertia, the impulse function balancing principle and the integration by parts algorithm were adopted to address the initial conditions of the differential equation. Based on the analytical expression, it can be analytically proved that a lower frequency deviation can be obtained under the same frequency regulation energy. Accordingly, a parameter-setting method for two-segment droop control was proposed. Finally, the effectiveness of the proposed method is verified by using a two-area system frequency response model, and the results reveal that it can be used to replace virtual inertia and has better performance.
目前,当可再生能源发电参与频率调节时,传统的控制方法是通过虚拟惯性控制来模拟同步发电机。然而,虚拟惯性有时间延迟,因此本质上是一种快速功率响应。同时,虚拟惯性控制很可能会受到频率波动的影响,因为它响应的是频率的导数。因此,在参与频率调节时,可再生能源的非虚拟惯性控制值得探讨。为此,本研究提出了一种用于可再生能源频率调节的新型两段式下垂控制方案。首先,建立包含时延虚拟惯性的扩展系统频率调节(SFR)模型,并基于 Routh 近似方法进行阶次递减分析求解。之后,根据解析解,时间延迟会影响可再生能源的频率响应。通过分析还可以证明,在相同的频率偏差下,非虚拟惯性控制(如唯一垂度控制)可以取代虚拟惯性控制。不过,频率调节可能需要更多能量。此外,本文还提出了一种新型的两段式下垂控制,并采用脉冲函数平衡原理和分部积分算法对微分方程的初始条件进行分析,以证明其替代虚拟惯性的能力。根据解析表达式,可以分析证明在相同频率调节能量下,可以获得较低的频率偏差。据此,提出了一种两段下垂控制的参数设置方法。最后,利用两区系统频率响应模型验证了所提方法的有效性,结果表明该方法可用于替代虚拟惯性,并具有更好的性能。
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引用次数: 0
Real-time detection of insider attacks on substation automation systems using short length orthogonal wavelet filters and OPAL-RT 利用短长正交小波滤波器和 OPAL-RT 实时检测变电站自动化系统的内部攻击
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-17 DOI: 10.1016/j.ijepes.2024.110311
M. Oinonen, W.G. Morsi
Substation Automation Systems (SASs) integrate communication networks with physical equipment and are vulnerable to cyberattacks. A subset of these attacks, namely Insider attacks, are launched from knowledgeable insiders and therefore they are typically difficult to detect. This paper presents a new method for detecting and classifying Insider cyberattacks as well as power disturbances on SASs using short-length orthogonal wavelet filters in real-time using an OPAL-Real-Time (OPAL-RT) simulator. An Intrusion Detection System (IDS) is proposed in which custom-designed wavelet filters of short length are developed to better extract both the network and physical data of the SASs into time–frequency spectrograms. The advantage of using the short length filters is to provide fast detection of these time-sensitive Insider attacks and disturbances in real-time, which is a key requirement for mitigation to be possible. The generated spectrograms are fed to a Convolutional Neural Network (CNN) that automates the classification process. An experimental dataset is developed from real-time testing using OPAL-RT that implements several types of cyberattacks including Insider attacks and other popular attacks such as Denial-of-Service and False Data Injection as well as challenging attacks such as Replay and Message Suppression attacks. The results of experimentally testing the proposed method in real-time using OPAL-RT demonstrate that the use of the short-length custom-designed orthogonal wavelet filters achieves a detection accuracy of 97.37 % compared to other methods as well as a low runtime of 33.786 ms.
变电站自动化系统 (SAS) 将通信网络与物理设备集成在一起,很容易受到网络攻击。这些攻击的一个子集,即内部攻击,是由见多识广的内部人员发起的,因此通常很难被检测到。本文提出了一种新方法,利用 OPAL-Real-Time (OPAL-RT) 模拟器,使用短长正交小波滤波器实时检测 SAS 上的内部网络攻击和电力干扰,并对其进行分类。我们提出了一种入侵检测系统 (IDS),其中开发了定制设计的短小波滤波器,以更好地将 SAS 的网络和物理数据提取到时频谱图中。使用短小波滤波器的好处是可以实时快速地检测到这些对时间敏感的内幕攻击和干扰,而这正是采取缓解措施的关键要求。生成的频谱图被送入卷积神经网络(CNN),从而自动完成分类过程。利用 OPAL-RT 实时测试开发了一个实验数据集,该数据集实现了多种类型的网络攻击,包括内部攻击和其他流行攻击(如拒绝服务和虚假数据注入),以及具有挑战性的攻击(如重播和信息抑制攻击)。使用 OPAL-RT 对所提出的方法进行实时实验测试的结果表明,与其他方法相比,使用定制设计的短长正交小波滤波器可实现 97.37 % 的检测准确率,并且运行时间仅为 33.786 毫秒。
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引用次数: 0
An energy trade-off management strategy for hybrid ships based on event-triggered model predictive control 基于事件触发模型预测控制的混合动力船舶能源权衡管理策略
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-17 DOI: 10.1016/j.ijepes.2024.110312
Diju Gao , Long Chen , Yide Wang
This paper addresses the energy management problem of hybrid ships by proposing an event-triggered model predictive control (ET-MPC) method. The novelty in this work lies in the establishment of an event-triggered mechanism and a state prediction model for energy management of hybrid ships. First, torque models of the internal combustion engine (ICE) and electric machine (EM) are developed using a data-driven approach, followed by the construction of fuel consumption and carbon emission models. Second, an event-triggered mechanism, dependent on state prediction error, is introduced and updated at each time step based on the system’s current state. Additionally, a cubature Kalman filter (CKF) is employed to estimate and correct the state prediction error, minimizing inaccuracies. A trade-off coefficient is incorporated to optimize the balance between fuel consumption and carbon emissions. The ET-MPC method results in a 0.68% difference in fuel consumption and 3.43% increase emissions compared to the traditional MPC method. However, ET-MPC significantly reduces computational overhead by 56.66. The ET-MPC method effectively allocates the ship’s energy according to the varying trade-off coefficient, achieving optimal energy management under different constraints.
本文针对混合动力船舶的能源管理问题,提出了一种事件触发模型预测控制(ET-MPC)方法。这项工作的新颖之处在于建立了事件触发机制和混合动力船舶能源管理的状态预测模型。首先,采用数据驱动方法开发了内燃机(ICE)和电机(EM)的扭矩模型,然后构建了燃料消耗和碳排放模型。其次,引入了一个取决于状态预测误差的事件触发机制,并根据系统的当前状态在每个时间步骤进行更新。此外,还采用立方卡尔曼滤波器(CKF)来估计和修正状态预测误差,从而最大限度地减少误差。此外,还加入了权衡系数,以优化燃料消耗和碳排放之间的平衡。与传统的 MPC 方法相比,ET-MPC 方法的燃油消耗量减少了 0.68%,排放量增加了 3.43%。然而,ET-MPC 大幅减少了 56.66 的计算开销。ET-MPC 方法根据不同的权衡系数有效地分配了船舶能源,实现了不同约束条件下的最优能源管理。
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引用次数: 0
Low-frequency oscillations in AC railway traction power systems: Train input admittance calculation and stability analysis 交流铁路牵引电力系统中的低频振荡:列车输入导纳计算和稳定性分析
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-17 DOI: 10.1016/j.ijepes.2024.110284
Paul Frutos , Juan Manuel Guerrero , Iker Muniategui , Aitor Endemaño , David Ortega , Fernando Briz
Dynamic interactions among the AC railway power supply network and power electronic converters feeding the trains can result in low-frequency oscillation (LFO) of the catenary voltage, leading to a power outage of the substation and the shutdown of train traffic. To determine the low-frequency stability of the railway traction power systems, the impedance of the power supply network and the total differential admittance of the trains are required. This paper addresses the development of an analytical small-signal model of the train input admittance. For this purpose, small-signal models of each dynamic element involved are obtained. Specifically, the small-signal vector transformation from the actual dq-frame to the estimated dq̂-frame is presented to model the dynamics due to errors in the coordinate rotation of the single-phase four-quadrant converter (4QC) control system. Furthermore, the quadrature signal generator second-order generalized integrator (QSG-SOGI) model is calculated in the synchronous frame. The developed admittance model is intended to accurately predict various types of instabilities and serve as a powerful tool for conducting sensitivity analyses. The validation of the proposed models will be carried out through numerical simulations involving the power supply network and train systems.
交流铁路供电网络和馈电列车的电力电子变流器之间的动态相互作用会导致牵引电压的低频振荡(LFO),从而导致变电站停电和列车停运。要确定铁路牵引供电系统的低频稳定性,需要了解供电网络的阻抗和列车的总差动导纳。本文探讨了列车输入导纳小信号分析模型的开发。为此,本文获得了每个相关动态元素的小信号模型。具体来说,本文介绍了从实际 dq 帧到估计 dq ̂ 帧的小信号矢量变换,以模拟单相四象限转换器 (4QC) 控制系统坐标旋转误差引起的动态。此外,还计算了同步帧中的正交信号发生器二阶广义积分器(QSG-SOGI)模型。所开发的导纳模型旨在准确预测各种类型的不稳定性,并作为进行敏感性分析的有力工具。将通过涉及供电网络和列车系统的数值模拟对所提出的模型进行验证。
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引用次数: 0
Stochastic dynamic power dispatch with high generalization and few-shot adaption via contextual meta graph reinforcement learning 通过上下文元图强化学习实现具有高泛化和少量适应性的随机动态电力调度
IF 5 2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-16 DOI: 10.1016/j.ijepes.2024.110272
Zhanhong Huang , Tao Yu , Zhenning Pan , Bairong Deng , Xuehan Zhang , Yufeng Wu , Qiaoyi Ding
Reinforcement learning, as an efficient method for solving uncertainty decision making in power systems, is widely used in multi-stage stochastic power dispatch and dynamic optimization. However, the low generalization and practicality of traditional reinforcement learning algorithms limit their online application. The dispatch strategy learned offline can only adapt to specific scenarios, and its policy performance degrades significantly if the sample drastically change or the topology variation. To fill these gaps, a novel contextual meta graph reinforcement learning (Meta-GRL) method a more general contextual Markov decision process (CMDP) modeling are proposed. The proposed Meta-GRL adopts CMDP scheme and graph representation, extracts and encodes the differentiated scene context, and can be extended to various scene changes. The upper meta-learner embedded in context in Meta-GRL is proposed to realize scene recognition. While the lower base-earner is guided to learn generalized context-specified policy. The test results in IEEE39 and open environment show that the Meta-GRL achieves more than 90% optimization and entire period applicability under the premise of saving computing resources.
强化学习作为解决电力系统不确定性决策的有效方法,被广泛应用于多阶段随机电力调度和动态优化。然而,传统强化学习算法的通用性和实用性较低,限制了其在线应用。离线学习到的调度策略只能适应特定场景,如果样本急剧变化或拓扑结构发生变化,其策略性能就会明显下降。为了填补这些空白,我们提出了一种新颖的上下文元图强化学习(Meta-GRL)方法和一种更通用的上下文马尔可夫决策过程(CMDP)模型。所提出的元图强化学习方法采用 CMDP 方案和图表示法,提取并编码差异化的场景上下文,并可扩展到各种场景变化。在 Meta-GRL 中提出了嵌入上下文的上层元学习器来实现场景识别。同时,指导下层基础学习器学习广义的上下文指定策略。在 IEEE39 和开放环境下的测试结果表明,在节省计算资源的前提下,Meta-GRL 实现了 90% 以上的优化和全时段适用性。
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引用次数: 0
saseR: Juggling offsets unlocks RNA-seq tools for fast and Scalable differential usage, Aberrant Splicing and Expression Retrieval. saseR: Juggling offsets解锁RNA-seq工具,实现快速、可扩展的差异使用、异常剪接和表达检索。
2区 工程技术 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-16 DOI: 10.1101/2023.06.29.547014
Alexandre Segers, Jeroen Gilis, Mattias Van Heetvelde, Davide Risso, Elfride De Baere, Lieven Clement

RNA-seq data analysis relies on many different tools, each tailored to specific applications and coming with unique assumptions and restrictions. Indeed, tools for differential transcript usage, or diagnosing patients with rare diseases through splicing and expression outliers, either lack in performance, discard information, or do not scale to massive data compendia. Here, we show that replacing the normalisation offsets unlocks bulk RNA-seq workflows for scalable differential usage, aberrant splicing and expression analyses. Our method, saseR, is much faster than state-of-the-art methods, dramatically outperforms these to detect aberrant splicing, and provides a single workflow for various short- and long-read RNA-seq applications.

RNA-seq 数据分析依赖于许多不同的工具,每种工具都是为特定应用量身定制的,并带有独特的假设和限制。事实上,用于差异转录本使用或通过剪接和表达异常值诊断罕见疾病患者的工具要么性能不足,要么丢弃信息,要么无法扩展到海量数据集。在这里,我们展示了替换归一化偏移量可以解锁批量 RNA-seq 工作流,从而进行可扩展的差异使用、异常剪接和表达分析。我们的方法(saseR)比最先进的方法快得多,在检测异常剪接方面大大优于这些方法,并为各种短线程和长线程 RNA-seq 应用提供了单一的工作流程。
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引用次数: 0
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International Journal of Electrical Power & Energy Systems
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