Pub Date : 2023-10-01DOI: 10.7546/crabs.2023.09.10
Alexander Chikalanov, Leoneed Kirilov, Eugenia Kovatcheva, Roumen Nikolov, Elena Shoikova, Alexander Iliev, Ljubomir Gotsev
The intensive development of hardware and software tools provides many opportunities for solving various real-world tasks, such as working with large data sets. This, in turn, is a powerful incentive and opportunity for the development of different approaches and tools for solving them. After discussing several well-known BigData architectures a model of a BigData architecture is designed. The architecture is organized in three sections: edge section, processing-and-storage section and application section. The model will be implemented using FIWARE components.
{"title":"A Model of Big Data Architecture on the Base of FIWARE Components","authors":"Alexander Chikalanov, Leoneed Kirilov, Eugenia Kovatcheva, Roumen Nikolov, Elena Shoikova, Alexander Iliev, Ljubomir Gotsev","doi":"10.7546/crabs.2023.09.10","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.10","url":null,"abstract":"The intensive development of hardware and software tools provides many opportunities for solving various real-world tasks, such as working with large data sets. This, in turn, is a powerful incentive and opportunity for the development of different approaches and tools for solving them. After discussing several well-known BigData architectures a model of a BigData architecture is designed. The architecture is organized in three sections: edge section, processing-and-storage section and application section. The model will be implemented using FIWARE components.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Numerous studies have indicated the significant importance of pelvic dose in the radiotherapy process for cervical cancer patients. However, research on the actual pelvic bone dose in the treatment of cervical cancer patients using different techniques is currently relatively limited. In this study, we selected 50 postoperative cervical cancer patients. For each patient, three treatment plans with pelvic dose constraints were designed: sIMRT, VMAT, and HT. Statistical analysis was conducted on the target area and organ at risk parameters of the three groups of plans. The results indicate that all three treatment plans meet the clinical requirements. Regarding organs at risk, compared to the sIMRT and VMAT groups, the HT group showed a reduction of 11.85% and 11.07%, respectively, in V40 of bladder. Additionally, compared to the sIMRT and HT groups, the VMAT group exhibited a reduction of 14.94% and 9.53%, respectively, in V10 of pelvic bone. Furthermore, compared to the sIMRT and HT groups, the VMAT group showed a reduction of 10.76% and 6.75%, respectively, in V20 of pelvic bone, and these differences were also statistically significant (t = 21.630, t = –16.621, P < 0.05). In summary, individualized treatment design can be conducted in clinical practice based on the specific conditions of patients.
大量研究表明盆腔剂量在宫颈癌患者放疗过程中具有重要意义。然而，目前对不同技术治疗宫颈癌患者的实际盆腔骨剂量的研究相对有限。在本研究中，我们选择了50例宫颈癌术后患者。对于每位患者，设计了三种骨盆剂量限制的治疗方案:sIMRT、VMAT和HT。对三组方案的靶区和危险器官参数进行统计分析。结果表明，三种治疗方案均符合临床要求。对于危险器官，与sIMRT和VMAT组相比，HT组膀胱V40分别降低11.85%和11.07%。此外，与sIMRT和HT组相比，VMAT组骨盆骨V10分别降低了14.94%和9.53%。VMAT组骨盆骨V20较sIMRT组和HT组分别降低10.76%和6.75%，差异也有统计学意义(t = 21.630, t = -16.621, P <0.05)。综上所述，在临床实践中可以根据患者的具体情况进行个性化的治疗设计。
{"title":"Dosimetric Analysis of Limiting Pelvic Bone Dose in Intensity-modulated Radiotherapy for Cervical Cancer","authors":"Hao Qiu, Xin Liu, Meifang Fang, Xianxiang Wu, Dawei Zhou, Hanfei Cai","doi":"10.7546/crabs.2023.09.16","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.16","url":null,"abstract":"Numerous studies have indicated the significant importance of pelvic dose in the radiotherapy process for cervical cancer patients. However, research on the actual pelvic bone dose in the treatment of cervical cancer patients using different techniques is currently relatively limited. In this study, we selected 50 postoperative cervical cancer patients. For each patient, three treatment plans with pelvic dose constraints were designed: sIMRT, VMAT, and HT. Statistical analysis was conducted on the target area and organ at risk parameters of the three groups of plans. The results indicate that all three treatment plans meet the clinical requirements. Regarding organs at risk, compared to the sIMRT and VMAT groups, the HT group showed a reduction of 11.85% and 11.07%, respectively, in V40 of bladder. Additionally, compared to the sIMRT and HT groups, the VMAT group exhibited a reduction of 14.94% and 9.53%, respectively, in V10 of pelvic bone. Furthermore, compared to the sIMRT and HT groups, the VMAT group showed a reduction of 10.76% and 6.75%, respectively, in V20 of pelvic bone, and these differences were also statistically significant (t = 21.630, t = –16.621, P < 0.05). In summary, individualized treatment design can be conducted in clinical practice based on the specific conditions of patients.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Technoeconomic, environmental and safety criteria generally affect the management of metallic and non-metallic mining operations. The first basic question that needs to be addressed when planning ore mining is which methods are adequate and what is the optimal mining technology? Due to the complex geologic framework of ore deposits, geological exploration has rendered synonymous the inherent uncertainties, vagueness, and inaccuracies. As a result, subjective evaluation by engineers and expert experience have become increasingly important. Given that the natural language used by miners and geologists is most suited for relaying knowledge and expressing opinions, the paper tests a fuzzy optimization methodology that uses linguistic variables. Consequently, extent analysis is applied to fuzzy AHP by means of triangular fuzzy numbers to arrive at a decision about the optimal mining technology. The entire procedure constitutes an integrated mine management system, which will contribute to sustainable production in the future. A case study to which the model was applied is presented in the paper.
{"title":"Development of Integrated Fuzzy Model for Mine Management Optimization","authors":"Miodrag Čelebić, Sanja Bajić, Dragoljub Bajić, Dejan Stevanović, Duško Torbica, Vladimir Malbašić","doi":"10.7546/crabs.2023.09.12","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.12","url":null,"abstract":"Technoeconomic, environmental and safety criteria generally affect the management of metallic and non-metallic mining operations. The first basic question that needs to be addressed when planning ore mining is which methods are adequate and what is the optimal mining technology? Due to the complex geologic framework of ore deposits, geological exploration has rendered synonymous the inherent uncertainties, vagueness, and inaccuracies. As a result, subjective evaluation by engineers and expert experience have become increasingly important. Given that the natural language used by miners and geologists is most suited for relaying knowledge and expressing opinions, the paper tests a fuzzy optimization methodology that uses linguistic variables. Consequently, extent analysis is applied to fuzzy AHP by means of triangular fuzzy numbers to arrive at a decision about the optimal mining technology. The entire procedure constitutes an integrated mine management system, which will contribute to sustainable production in the future. A case study to which the model was applied is presented in the paper.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.7546/crabs.2023.09.07
Nikola Pirovski, Dimitrinka Atanasova, Donka Keskinova, Nikolay Dimitrov
The effects of ageing on the oral mucosa are believed to be relatively small. The purpose of this study was to identify morphological changes observed in rat tongue during ageing in 20-day-old, 3-month-old, 12-month-old, 28-month-old, and 48-month-old rats. Age-related changes in the thickness of the epithelium and lamina propria, the density of the elastic fibres and the number of mast cells were histomorphometrically analyzed. In 20-day-old rats, the stratified squamous epithelium and lamina propria thicknesses were thinnest, whereas with age, epithelial thickness reached its greatest thickness in 48-month-old rats and lamina propria thickness was most noticeable in 12-month-old rats. The arrangement and distribution of elastic fibres were disrupted in the lamina propria with ageing. The density of elastic fibres in lamina propria was lowest in 20-day-old rats, while in 12-month-old rats they reached their highest density, and then decreased sharply again in older rats. The number of mast cells per unit area was lowest in 20-day-old rats, reaching its highest number in 12-month-old rats and remaining high in older animals. In conclusion, with age, there was a moderate positive correlation and a statistically significant increase in tongue epithelial thickness, as well as a significant thickening of the lamina propria and an increase in the number of mast cells. The density of the elastic fibres in lamina propria decreased, but no negative correlation was observed with ageing.
{"title":"Age-related Changes in Rat Tongue","authors":"Nikola Pirovski, Dimitrinka Atanasova, Donka Keskinova, Nikolay Dimitrov","doi":"10.7546/crabs.2023.09.07","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.07","url":null,"abstract":"The effects of ageing on the oral mucosa are believed to be relatively small. The purpose of this study was to identify morphological changes observed in rat tongue during ageing in 20-day-old, 3-month-old, 12-month-old, 28-month-old, and 48-month-old rats. Age-related changes in the thickness of the epithelium and lamina propria, the density of the elastic fibres and the number of mast cells were histomorphometrically analyzed. In 20-day-old rats, the stratified squamous epithelium and lamina propria thicknesses were thinnest, whereas with age, epithelial thickness reached its greatest thickness in 48-month-old rats and lamina propria thickness was most noticeable in 12-month-old rats. The arrangement and distribution of elastic fibres were disrupted in the lamina propria with ageing. The density of elastic fibres in lamina propria was lowest in 20-day-old rats, while in 12-month-old rats they reached their highest density, and then decreased sharply again in older rats. The number of mast cells per unit area was lowest in 20-day-old rats, reaching its highest number in 12-month-old rats and remaining high in older animals. In conclusion, with age, there was a moderate positive correlation and a statistically significant increase in tongue epithelial thickness, as well as a significant thickening of the lamina propria and an increase in the number of mast cells. The density of the elastic fibres in lamina propria decreased, but no negative correlation was observed with ageing.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.7546/crabs.2023.09.03
Georgi Kotlarski, Nikolay Ivanov, Dimitar Dechev, Maria Ormanova, Stefan Valkov, Valentin Mateev, Iliana Marinova
In this work, TiN and VN coatings were applied on aluminium electrodes by direct current (DC) magnetron sputtering in order to study the influence of the protective coatings on the electrical impedance of the substrate. The structure of the samples was studied using X-ray diffraction (XRD). The microhardness of the substrate and the coated samples was also determined. The electrical impedance of the substrates with and without coatings was also studied and the results were used for evaluation of the applicability of such coatings for interface electrodes for flexible electronics. Electric impedance spectroscopy in a wide frequency range was applied for interlayer and surface contact properties determination. Results showed improved stability and conductivity of the electrodes coated using the TiN and VN thin films, particularly in the low frequency range.
{"title":"Influence of Magnetron Sputtered TiN and VN Coatings on the Electrical Impedance of Aluminium Electrodes","authors":"Georgi Kotlarski, Nikolay Ivanov, Dimitar Dechev, Maria Ormanova, Stefan Valkov, Valentin Mateev, Iliana Marinova","doi":"10.7546/crabs.2023.09.03","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.03","url":null,"abstract":"In this work, TiN and VN coatings were applied on aluminium electrodes by direct current (DC) magnetron sputtering in order to study the influence of the protective coatings on the electrical impedance of the substrate. The structure of the samples was studied using X-ray diffraction (XRD). The microhardness of the substrate and the coated samples was also determined. The electrical impedance of the substrates with and without coatings was also studied and the results were used for evaluation of the applicability of such coatings for interface electrodes for flexible electronics. Electric impedance spectroscopy in a wide frequency range was applied for interlayer and surface contact properties determination. Results showed improved stability and conductivity of the electrodes coated using the TiN and VN thin films, particularly in the low frequency range.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.7546/crabs.2023.09.04
Roumen Tsekov
Advanced thermostats for molecular dynamics are proposed on the base of the rigorous Langevin dynamics. Because the latter accounts for the subsystem-bath interactions in detail, the bath anisotropy and nonuniformity are described via the relevant friction tensor. The developed model reflects properly the relativistic dynamics of the subsystem evolution as well as the nonlinear friction, which can occur for fast particles with large momenta at elevated temperature.
{"title":"Advanced Thermostats for Molecular Dynamics","authors":"Roumen Tsekov","doi":"10.7546/crabs.2023.09.04","DOIUrl":"https://doi.org/10.7546/crabs.2023.09.04","url":null,"abstract":"Advanced thermostats for molecular dynamics are proposed on the base of the rigorous Langevin dynamics. Because the latter accounts for the subsystem-bath interactions in detail, the bath anisotropy and nonuniformity are described via the relevant friction tensor. The developed model reflects properly the relativistic dynamics of the subsystem evolution as well as the nonlinear friction, which can occur for fast particles with large momenta at elevated temperature.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135407292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.7546/crabs.2023.08.08
Irena Kostova, Denitsa Apostolova, Maya Stefanova
The study fills the informative gap on occurrence, distribution, and carcinogenicity of polycyclic aromatic hydrocarbons (PAHs) in Bulgarian coals. It presents quantitative data for content and carcinogenicity of PAHs in different rank raw coals from eight basins with geological age from Late Carboniferous to Late Miocene, Ro=0.17–5.20%. The high amounts of alkylated naphthalene and alkylated phenanthrene determined in the bituminous coals reflect the diagenetic conversion of the plant-derived terpenoids into alkylated PAHs.
In this first systematic study of PAHs in Bulgarian raw coals three concentration ranges are established: for Miocene/Eocene age coal – from 1.08 mg/kg to 5.79 mg/kg; for Late Cretaceous/Late Carboniferous age coal – from 77.9 mg/ kg to 137.2 mg/kg; and, for the Late Carboniferous coal – 1.85 mg/kg. The relationship of the total PAHs content vs. raw coal Ro shapes as a “bell” and matches with the published data for the native PAHs from all over the world provenance. The maximal PAHs amount of 137.2 mg/kg at Ro =0.96% for the Late Cretaceous coal lies within the “oil-generation window”, Ro =0.5–1.3% for the kerogen. For all raw coal studied relatively low carcinogenicity is determined based on the well correlated values for B[a]Peq and TEQ parameters.
{"title":"Polycyclic Aromatic Hydrocarbons (PAHs) in Bulgarian Coals: Occurrence, Distribution and Carcinogenicity","authors":"Irena Kostova, Denitsa Apostolova, Maya Stefanova","doi":"10.7546/crabs.2023.08.08","DOIUrl":"https://doi.org/10.7546/crabs.2023.08.08","url":null,"abstract":"The study fills the informative gap on occurrence, distribution, and carcinogenicity of polycyclic aromatic hydrocarbons (PAHs) in Bulgarian coals. It presents quantitative data for content and carcinogenicity of PAHs in different rank raw coals from eight basins with geological age from Late Carboniferous to Late Miocene, Ro=0.17–5.20%. The high amounts of alkylated naphthalene and alkylated phenanthrene determined in the bituminous coals reflect the diagenetic conversion of the plant-derived terpenoids into alkylated PAHs.
 In this first systematic study of PAHs in Bulgarian raw coals three concentration ranges are established: for Miocene/Eocene age coal – from 1.08 mg/kg to 5.79 mg/kg; for Late Cretaceous/Late Carboniferous age coal – from 77.9 mg/ kg to 137.2 mg/kg; and, for the Late Carboniferous coal – 1.85 mg/kg. The relationship of the total PAHs content vs. raw coal Ro shapes as a “bell” and matches with the published data for the native PAHs from all over the world provenance. The maximal PAHs amount of 137.2 mg/kg at Ro =0.96% for the Late Cretaceous coal lies within the “oil-generation window”, Ro =0.5–1.3% for the kerogen. For all raw coal studied relatively low carcinogenicity is determined based on the well correlated values for B[a]Peq and TEQ parameters.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136248645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-30DOI: 10.7546/crabs.2023.04.02
Penka Mayster, Assen Tchorbadjieff
The subcritical Markov branching process X(t) starting with one particle as the initial condition has the ultimate extinction probability q = 1. The branching mechanism in consideration is defined by the mixture of logarithmic distributions on the nonnegative integers. The purpose of the present paper is to prove that in this case the random number of particles X(t) alive at time t > 0 follows the shifted extended Sibuya distribution, with parameters depending on the time t > 0. The conditional limit probability is the logarithmic series distribution supported by the positive integers.
{"title":"Extended Sibuya Distribution in Subcritical Markov Branching Processes","authors":"Penka Mayster, Assen Tchorbadjieff","doi":"10.7546/crabs.2023.04.02","DOIUrl":"https://doi.org/10.7546/crabs.2023.04.02","url":null,"abstract":"The subcritical Markov branching process X(t) starting with one particle as the initial condition has the ultimate extinction probability q = 1. The branching mechanism in consideration is defined by the mixture of logarithmic distributions on the nonnegative integers. The purpose of the present paper is to prove that in this case the random number of particles X(t) alive at time t > 0 follows the shifted extended Sibuya distribution, with parameters depending on the time t > 0. The conditional limit probability is the logarithmic series distribution supported by the positive integers.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135603751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is a vast body of evidence in favour of individualising fluid therapy using dynamic hemodynamic indices like stroke volume variation (SVV). Patients with implanted intra-aortic balloon pump (IABP) are excluded from this approach because of pulse contour artifacts caused by the pump. The aim of this work is to test whether SVV can be used for fluid responsiveness prediction in these patients. Patients after cardiac surgery with implanted IABP were included in this study. SVV was measured after placing the IABP on standby mode for one minute. Cardiac output (CO) measurement was obtained via Swan-Ganz catheter before and after a 6 ml/kg fluid challenge. Fluid responsiveness was defined as increase of CO by at least 10%. SVV above 8.5% showed a good correlation with fluid responsiveness. Sensitivity was 95 (95% CI 85 to 100) and specificity 82 (95% CI 72 to 92). SVV had an area under the ROC curve 0.91 (95% CI 0.81 to 1.0) SVV is a good predictor of fluid responsiveness in patients with IABP. SVV should not be excluded as a fluid therapy guide for these patients. Placing the pump on standby for one minute allows obtaining an accurate measurement of this important variable.
有大量的证据支持使用动态血流动力学指标如脑卒中容积变化(SVV)进行个体化液体治疗。植入主动脉内球囊泵(IABP)的患者由于泵引起的脉冲轮廓伪影而被排除在该方法之外。这项工作的目的是测试SVV是否可以用于预测这些患者的液体反应性。本研究纳入了心脏手术后植入IABP的患者。将IABP置于待机模式一分钟后测量SVV。心输出量(CO)测量通过Swan-Ganz导管在6 ml/kg液体刺激前后。流体响应性定义为CO增加至少10%。SVV高于8.5%与流体反应性有良好的相关性。敏感性为95 (95% CI 85 ~ 100)，特异性为82 (95% CI 72 ~ 92)。SVV的ROC曲线下面积为0.91 (95% CI 0.81 ~ 1.0) SVV是IABP患者液体反应性的良好预测因子。不应排除SVV作为这些患者的液体治疗指南。将泵置于待机状态一分钟，可以获得对这一重要变量的准确测量。
{"title":"Stroke Volume Variation is a Good Predictor of Fluid Responsiveness in Cardiac Surgery Patients with Implanted Intra-aortic Balloon Pump","authors":"Rostislav Enev, Fillip Abedinov, Neda Bakalova, Margarita Atanasova, Nezabravka Chilingirova, Plamen Krastev","doi":"10.7546/crabs.2023.04.14","DOIUrl":"https://doi.org/10.7546/crabs.2023.04.14","url":null,"abstract":"There is a vast body of evidence in favour of individualising fluid therapy using dynamic hemodynamic indices like stroke volume variation (SVV). Patients with implanted intra-aortic balloon pump (IABP) are excluded from this approach because of pulse contour artifacts caused by the pump. The aim of this work is to test whether SVV can be used for fluid responsiveness prediction in these patients. Patients after cardiac surgery with implanted IABP were included in this study. SVV was measured after placing the IABP on standby mode for one minute. Cardiac output (CO) measurement was obtained via Swan-Ganz catheter before and after a 6 ml/kg fluid challenge. Fluid responsiveness was defined as increase of CO by at least 10%. SVV above 8.5% showed a good correlation with fluid responsiveness. Sensitivity was 95 (95% CI 85 to 100) and specificity 82 (95% CI 72 to 92). SVV had an area under the ROC curve 0.91 (95% CI 0.81 to 1.0) SVV is a good predictor of fluid responsiveness in patients with IABP. SVV should not be excluded as a fluid therapy guide for these patients. Placing the pump on standby for one minute allows obtaining an accurate measurement of this important variable.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135603758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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