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Estimation of the Duration of Covid-19 Epidemic in a Single Country, with or without Vaccinations. The Case of Bulgaria and Germany 在接种疫苗或未接种疫苗的情况下估算单个国家Covid-19流行持续时间。保加利亚和德国的案例
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2021-06-20 DOI: 10.7546/CRABS.2021.05.05
O. Kounchev, G. Simeonov, Z. Kuncheva
In the present paper we develop a methodology for the estimation of the duration of the Epidemic of Covid-19 in a single country, with or without vaccinations, accounting for different scenarios. Our methodology is based on a specific SEIR model, called ATVBG-SEIR model, which is explained in detail. The results are especially interesting for vaccination-free society since they show what the Covid-19 mortality would be in different scenarios. We include vaccinations in the model which are carried out according to a vaccination plan provided on a daily basis. The main constraint to be accounted by the methodology is the number of Intensive Care Units (ICU) reserved for Covid-19 patients (they are e.g. about 1100 in Bulgaria, about 8000 in Germany, etc.). A Web-based Lockdown Scenarios Tool has been developed, based on the present methodology, which is available at www.atvbg-seir.eu. Results in the paper are demonstrating the efficiency of the tool by applying it to Covid-19 data from Bulgaria and Germany, while in the tool we provide online models for Austria, Bulgaria, Germany, Italy, UK and USA. © 2021 Academic Publishing House. All rights reserved.
在本文中,我们开发了一种方法,用于估计在接种或不接种疫苗的情况下单个国家Covid-19流行的持续时间,并考虑了不同的情况。我们的方法是基于一个特定的SEIR模型,称为ATVBG-SEIR模型,这是详细解释。这些结果对于无疫苗接种的社会来说特别有趣,因为它们显示了不同情况下Covid-19的死亡率。我们在模型中包括根据每天提供的疫苗接种计划进行的疫苗接种。该方法要考虑的主要限制因素是为Covid-19患者保留的重症监护病房(ICU)的数量(例如,保加利亚约为1100个,德国约为8000个,等等)。根据目前的方法,开发了一个基于网络的封锁情景工具,可在www.atvbg-seir.eu上获得。通过将该工具应用于保加利亚和德国的Covid-19数据,本文的结果证明了该工具的有效性,而在该工具中,我们提供了奥地利、保加利亚、德国、意大利、英国和美国的在线模型。©2021学术出版社。版权所有。
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引用次数: 3
Lidar monitoring and in situ sampling of particulate matter in lowest atmospheric layers over urban area 城市地区低层大气颗粒物的激光雷达监测和原位采样
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2021-01-01 DOI: 10.7546/CRABS.2021.09.04
I. Grigorov, C. Ghelev, G. Kolarov, M. Iliev, B. Angelova, R. Ilieva, V. Groudeva, Z. Cherkezova-Zheleva, D. Stoyanov, I. Nedkov
The present study is related to elucidating the remote sensing monitoring and capabilities for profiling to particulate matter (PM) mass concentration control in the lowest atmospheric layers. The PM was studied at a distance of 5.5 km from the LIDAR station. The experiments were conducted in May and October 2020 in the South-Eastern part of the Bulgarian capital Sofia during a COVID-19 lockdown. The LIDAR measurement data was compared during the experiments with in situ sampling by mobile devices located just below the spot of the LIDAR beam: (i) Absorber collects particles higher than 3 μm;(ii) PM Microcollector type SDS 011;and (iii) Andersen Cascade Impactor for exploring PM size distribution and microbiota. The results obtained show that remote sensing can be very effective when quantitative evaluation has been combined with in situ sampling for PM qualitative assessment. © 2021 Academic Publishing House. All rights reserved.
本研究旨在阐明遥感监测和对大气低层颗粒物(PM)质量浓度控制的能力。PM在距离激光雷达站5.5公里处进行研究。这些实验是在2019冠状病毒病封锁期间于2020年5月和10月在保加利亚首都索菲亚东南部进行的。在实验过程中,将激光雷达测量数据与位于激光雷达光束点下方的移动设备的原位采样数据进行了比较:(i)吸收器收集大于3 μm的颗粒;(ii) SDS 011型PM微收集器;(iii) Andersen级联冲击器用于探索PM尺寸分布和微生物群。结果表明,将遥感定量评价与现场采样相结合,可以有效地进行PM定性评价。©2021学术出版社。版权所有。
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引用次数: 1
Viral Respiratory Pathogens Associated with Medically Attended Acute Respiratory Illnesses in Older Adults in Bulgaria 保加利亚老年人急性呼吸道疾病与病毒性呼吸道病原体相关
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2020-05-20 DOI: 10.7546/crabs.2020.04.07
N. Korsun, S. Angelova, I. Trifonova, I. Georgieva, S. Voleva
Acute respiratory infections (ARIs) are a major cause of morbidity and mortality among older adults This study aimed to determine the viral etiology of these infections in patients aged >= 65 years during two successive epidemic seasons in Bulgaria Nasal and throat specimens were collected from the enrolled patients during the 2015/2016 and 2016/2017 seasons The viral etiology was determined by individual Real Time PCR assays against 15 respiratory viruses Of the 160 adults examined, 74 (46 3%) were positive for at least one respiratory virus Co-infections with two and three viruses were found in 14 (18 9%) of the infected patients Influenza A(H3N2) (15 6%) and A(H1N1)pdm09 (13 1%) viruses were the predominant pathogens, followed by adenoviruses (5 6%);respiratory-syncytial virus (3 8%);metapneumovirus (3 1%);rhinoviruses (2 5%);coronaviruses - NL63 (2 5%), OC43 (1 9%), HKU1 (1 9%) and 229E (1 3%);influenza type B (1 9%);bocaviruses (1 3%) and parainfluenza viruses 1/2/3 (1 3%) At least one respiratory virus was identified in 50% and 32 3% of the patients with acute lower respiratory tract illnesses and neurological complications, respectively Respiratory viruses, especially influenza A viruses, are major pathogens of ARIs in persons aged >= 65 years Diagnostic testing for respiratory viruses using molecular methods can help in clinical decision making and may assist in measures to prevent health careassociated infections
急性呼吸道感染(ARIs)是保加利亚连续两个流行季节中年龄> 65岁患者这些感染的病毒病因学研究在2015/2016和2016/2017两个流行季节收集了入组患者的鼻和咽喉标本,通过对160名被检查成年人中的15种呼吸道病毒进行实时荧光定量PCR检测确定了病毒病因学。1种以上呼吸道病毒阳性74例(46.3%),2、3病毒共感染14例(18.9%),以甲型流感病毒(H3N2)(15.6%)和甲型H1N1 pdm09(13.1%)病毒为主,其次为腺病毒(5.6%)、呼吸道合胞病毒(3.8%)、偏肺病毒(3.1%)、鼻病毒(2.5%)、冠状病毒- NL63(2.5%)、OC43(1.9%)、鼻病毒(2.5%)。HKU1(1.9%)和229E(1.3%);乙型流感(1.9%);bocavavirus(1.3%)和副流感病毒1/2/3(1.3%)。在急性下呼吸道疾病和神经系统并发症患者中,分别有50%和32.3%的患者中发现至少一种呼吸道病毒,其中呼吸道病毒,尤其是甲型流感病毒;使用分子方法对呼吸道病毒进行诊断检测有助于临床决策,并可能有助于采取措施预防卫生保健相关感染
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引用次数: 0
Determination of Porosity of Textiles with an Uneven Pore Size 孔径不均匀纺织品孔隙率的测定
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2020-02-10 DOI: 10.7546/crabs.2020.01.12
R. Angelova
The research studies in the porosity of textile macrostructures have always been relevant, but they have undergone significant progress with the development of optical devices and computer facilities. The main reason for this continuous interest is the strong correlation between textile porosity and the transfer of heat, fluids, and matter. Adequate porosity determination is needed for estimation of the influence of the macrostructure’s parameters on the transfer abilities of the textiles and their adequate design. The present study aims to experimentally determine the porosity of textile macrostructures with uneven pores, using image analysis. Microscopic images of seven fabrics were converted to binary images, and the pore content was assessed. The results were verified with a classical method for the determination of porosity of woven macrostructures. The obtained results show a very good correlation with the theoretical porosity of woven macrostructures. The proposed image analysis can be used for the determination of porosity of other types of textile macrostructures with uneven pore size.
纺织品宏观结构孔隙率的研究一直备受关注,但随着光学设备和计算机设备的发展,这些研究取得了重大进展。这种持续关注的主要原因是纺织品孔隙率与热、流体和物质的传递之间存在很强的相关性。为了评估宏观结构参数对纺织品传递能力的影响,并对纺织品进行适当的设计,需要进行充分的孔隙率测定。本研究的目的是利用图像分析的方法,通过实验确定具有不均匀孔隙的纺织品宏观结构的孔隙率。将7种织物的显微图像转换为二值图像,并对其孔隙含量进行评估。用经典的织物宏观结构孔隙率测定方法对所得结果进行了验证。所得结果与编织宏观结构的理论孔隙率有很好的相关性。所提出的图像分析方法可用于测定其他类型孔径不均匀的纺织品宏观结构的孔隙率。
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引用次数: 0
Nectria decora (Hypocreales) Associated with Fusarium lateritium in Bulgaria 在保加利亚与红土镰刀菌有关的赤藓
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-10-28 DOI: 10.7546/crabs.2018.10.06
D. Stoykov, P. Alvarado, Z. Stoyanova
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引用次数: 1
Developmental Stability of the Golden Jackal (Canis aureus moreoticus Geoffrey 1835) Populations in Southeastern Europe 东南欧金豺(Canis aureus moreoticus Geoffrey 1835)种群的发育稳定性
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-07-21 DOI: 10.7546/CRABS.2018.07.07
G. Markov, M. Heltai, Ivan Nikolov, A. Penezić, J. Lanszki, D. Ćirović
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引用次数: 0
Grapevine Leaf Area Measurements by Using Pixel Values 利用像素值测量葡萄叶面积
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-06-30 DOI: 10.7546/CRABS.2018.06.07
A. Doğan, C. Uyak, N. Keskin, Anil Akcay, Ruhan Ilknur, G. Şensoy, S. Ercişli
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引用次数: 5
Trophoblast Cell Lines JAR and JEG-3 Modulate CD90 (Thy‑1) Expression on Decidual Stromal Cells 滋养细胞JAR和JEG-3调节CD90 (Thy - 1)在蜕质细胞上的表达
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-06-30 DOI: 10.7546/CRABS.2018.06.10
K. Vinketova, I. Karaguozov, M. Mourdjeva, M. Sperandio, T. Oreshkova
CD90 is a glycoprotein involved in leukocyte homing and cell differentiation. In human endometrium CD90 is described on endothelial and stromal cells. If pregnancy occurs, the tissue is infiltrated by immune and trophoblast cells, which cooperate to remodel the tissue. The process requires a fine regulation of cell adhesion and migration. The expression of CD90 on cultured decidual stromal cells and its modulation by trophoblast cells from JAR and JEG-3 cell lines via soluble factors are investigated by flow cytometry. Some of decidual stromal cell lines showed ubiquitous expression of CD90 but in others a coexistence of CD90(high) and CD90(low) decidual stromal cells was observed. Further, a reduction of CD90 expression on decidual stromal cells was defined when decidual stromal cells communicate with trophoblast cells via soluble factors. The results sugguest a trophoblast guided differentiation of decidual stromal cells that could influence immune cells migration and tissue distribution.
CD90是一种参与白细胞归巢和细胞分化的糖蛋白。在人子宫内膜中,CD90被描述为内皮细胞和基质细胞。如果怀孕,组织被免疫细胞和滋养细胞浸润,它们合作重塑组织。这个过程需要对细胞粘附和迁移进行精细的调节。用流式细胞术研究了CD90在体外培养的JAR和JEG-3细胞间质细胞中的表达及其在滋养细胞中通过可溶性因子的调节作用。一些细胞系普遍表达CD90,而另一些细胞系则同时表达CD90(高)和CD90(低)。此外,当蜕膜细胞通过可溶性因子与滋养细胞沟通时,CD90在蜕膜细胞上的表达减少。结果提示,滋养细胞引导的蜕质细胞分化可能影响免疫细胞的迁移和组织分布。
{"title":"Trophoblast Cell Lines JAR and JEG-3 Modulate CD90 (Thy‑1) Expression on Decidual Stromal Cells","authors":"K. Vinketova, I. Karaguozov, M. Mourdjeva, M. Sperandio, T. Oreshkova","doi":"10.7546/CRABS.2018.06.10","DOIUrl":"https://doi.org/10.7546/CRABS.2018.06.10","url":null,"abstract":"CD90 is a glycoprotein involved in leukocyte homing and cell differentiation. In human endometrium CD90 is described on endothelial and stromal cells. If pregnancy occurs, the tissue is infiltrated by immune and trophoblast cells, which cooperate to remodel the tissue. The process requires a fine regulation of cell adhesion and migration. The expression of CD90 on cultured decidual stromal cells and its modulation by trophoblast cells from JAR and JEG-3 cell lines via soluble factors are investigated by flow cytometry. Some of decidual stromal cell lines showed ubiquitous expression of CD90 but in others a coexistence of CD90(high) and CD90(low) decidual stromal cells was observed. Further, a reduction of CD90 expression on decidual stromal cells was defined when decidual stromal cells communicate with trophoblast cells via soluble factors. The results sugguest a trophoblast guided differentiation of decidual stromal cells that could influence immune cells migration and tissue distribution.","PeriodicalId":50652,"journal":{"name":"Comptes Rendus De L Academie Bulgare Des Sciences","volume":"77 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90975497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Epigenetic Variation and Distinctness of Golden Jackal (Canis aureus) Populations in its Expanding South-east European Range 扩大的东南欧地区金豺(Canis aureus)种群的表观遗传变异和独特性
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-06-30 DOI: 10.7546/CRABS.2018.06.09
G. Markov, M. Heltai, Ivan Nikolov, A. Penezić, J. Lanszki, D. Ćirović
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引用次数: 4
New data from graptolites and quartz arenites for the Ordovician–Silurian boundary in the Murzuq Basin, Libya 利比亚Murzuq盆地奥陶系-志留系界线笔石和石英砂岩的新资料
IF 0.3 4区 综合性期刊 Q4 MULTIDISCIPLINARY SCIENCES Pub Date : 2018-05-02 DOI: 10.7546/CRABS.2018.04.09
V. Sachanski, D. K. Loydell, A. Chatalov
The graptolite-bearing interval in well A1-NC101, Libya indicates a Hirnantian age (persculptus graptolite Zone) for the lowermost Tanezzuft Fm based on the presence and stratigraphical distribution of N.? pseudovenustus. In the C1-NC101 core, the presence of N. inazaouae (recognised for the first time outside Algeria) and M. parvulus indicates either the uppermost Ordovician or the lowermost Silurian, but the revised total stratigraphical range of N. targuii (ascensus-acuminatus graptolite Zone) suggests an earliest Rhuddanian age. Several specimens of N. targuii are longer than those previously recorded. Pure quartz arenites of the uppermost Mamuniyat Fm (well A1-NC101) were deposited during the end-Hirnantian deglaciation probably in a nearshore marine environment. Their provenance was associated with sedimentary recycling of mature sands that were formed across North Gondwana in Cambrian and pre-glacial Ordovician times.
根据N.?的存在和地层分布,利比亚A1-NC101井含笔石层段为Tanezzuft Fm下部的Hirnantian时代(persculptus笔石带)。pseudovenustus。C1-NC101岩心中首次发现的N. inazaouae(阿尔及利亚以外首次发现)和M. parvulus表明其存在于奥陶系上端或志留系下端,而修正后的N. targuii (ascensus-acuminatus笔石带)的总地层范围表明其存在于最早的吕达尼世。一些targuii的标本比以前记录的要长。纯石英砂岩(A1-NC101井)沉积于第三纪末脱冰期,可能为近岸海洋环境。它们的物源与寒武纪和前冰期奥陶纪在北冈瓦纳形成的成熟砂的沉积再循环有关。
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引用次数: 1
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Comptes Rendus De L Academie Bulgare Des Sciences
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