K. Khaleeq, Zabihullah Farkhari, Ahmad Munir Amini, Ahmadullah Ahmadi, M. Samim, Muhammad Atiq Ashraf, Shamina Frotan
A field experiment Conducted at the farm of Kunduz University during cropping season of 2023 to evaluate Effects of Nitrogen Application on Growth and Yield of Groundnut (Arachis hypogaea L.) in northeast of Afghanistan. The field experiment laid out in Randomized Complete Block Design with three replications, the treatments were Nitrogen fertilizer levels viz. Control, 15 kg N/ha, 30 kg N/ha and 45 kg N/ha respectively, result of the study revealed the highest Plant Height (32.61cm), Branches/plant (10.05), Leave area index (5.20), Kernel/pod (2.23), Pod weight (24.46), Pods/plant (32.30), 100- seed weight (76.38gr), Pod yield (2.89t/ha), haulm yield (5.53t/ha) and Biological yield (8.42t/ha) were in treatment with application 45 kg N/ha, the minimum growth and yield parameters were in Control plots, it can be concluded nitrogen fertilizer at the rate of 45 kg N/ha is optimum level for enhancing groundnut productivity and profitability in northeast of Afghanistan.
{"title":"Effects of Nitrogen Application on Growth and Yield of Groundnut (Arachis hypogaea L.) in Northeast Agro-Ecology of Afghanistan","authors":"K. Khaleeq, Zabihullah Farkhari, Ahmad Munir Amini, Ahmadullah Ahmadi, M. Samim, Muhammad Atiq Ashraf, Shamina Frotan","doi":"10.55544/jrasb.3.2.3","DOIUrl":"https://doi.org/10.55544/jrasb.3.2.3","url":null,"abstract":"A field experiment Conducted at the farm of Kunduz University during cropping season of 2023 to evaluate Effects of Nitrogen Application on Growth and Yield of Groundnut (Arachis hypogaea L.) in northeast of Afghanistan. The field experiment laid out in Randomized Complete Block Design with three replications, the treatments were Nitrogen fertilizer levels viz. Control, 15 kg N/ha, 30 kg N/ha and 45 kg N/ha respectively, result of the study revealed the highest Plant Height (32.61cm), Branches/plant (10.05), Leave area index (5.20), Kernel/pod (2.23), Pod weight (24.46), Pods/plant (32.30), 100- seed weight (76.38gr), Pod yield (2.89t/ha), haulm yield (5.53t/ha) and Biological yield (8.42t/ha) were in treatment with application 45 kg N/ha, the minimum growth and yield parameters were in Control plots, it can be concluded nitrogen fertilizer at the rate of 45 kg N/ha is optimum level for enhancing groundnut productivity and profitability in northeast of Afghanistan.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In biological laboratories, contamination can arise from various sources, including airborne particles, equipment, reagents, and human error. Common contaminants responsible for spoilage in biological laboratories include bacteria, fungi, virus etc. Bacteria are ubiquitous in the environment and can contaminate laboratory samples, cultures, and media. There is a possibility of transferring microorganisms from one laboratory to the other during the course of activities that involves moving of materials. In this present work we had been identify three bacterial species like Staphylococcus aureus, Klebsiella pneumonia, Enterococcus Sp. which responsible for lab spoilage. Therefore measures like cleaning of lab, using protective gears, autoclaving of glassware needed to minimize lab contamination.
{"title":"Bacteriological Profile of Common Lab Contaminants Responsible for Spoilage in Biological Laboratory","authors":"Kanchan Shri Chauhan, Akshya Kumar Mishra","doi":"10.55544/jrasb.3.2.6","DOIUrl":"https://doi.org/10.55544/jrasb.3.2.6","url":null,"abstract":"In biological laboratories, contamination can arise from various sources, including airborne particles, equipment, reagents, and human error. Common contaminants responsible for spoilage in biological laboratories include bacteria, fungi, virus etc. Bacteria are ubiquitous in the environment and can contaminate laboratory samples, cultures, and media. There is a possibility of transferring microorganisms from one laboratory to the other during the course of activities that involves moving of materials. In this present work we had been identify three bacterial species like Staphylococcus aureus, Klebsiella pneumonia, Enterococcus Sp. which responsible for lab spoilage. Therefore measures like cleaning of lab, using protective gears, autoclaving of glassware needed to minimize lab contamination.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140777347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We talked about the existence of cosmic dust particles in this article, which are composed of different elements like carbon, oxygen, iron, and other atoms heavier than hydrogen and helium. Star formation depends on cosmic dust particles, which are the building blocks of planets and people. Dust that has fallen to Earth or exists in space is known as cosmic dust, sometimes known as extraterrestrial dust or space dust. The majority of particles of cosmic dust have sizes between a few molecules and 0.1 mm (100 µm). We refer to larger particles as meteorites. Cosmic dust is thought to be the remnants of asteroidal or cometary collisions that can be linked to collisions that took place during the Big Bang.
{"title":"Evaluations Using Clouds of Tiny Cosmic Dust Particles","authors":"Rahmatullah Lewal, Sherwali Hemat","doi":"10.55544/jrasb.3.2.1","DOIUrl":"https://doi.org/10.55544/jrasb.3.2.1","url":null,"abstract":"We talked about the existence of cosmic dust particles in this article, which are composed of different elements like carbon, oxygen, iron, and other atoms heavier than hydrogen and helium. Star formation depends on cosmic dust particles, which are the building blocks of planets and people. Dust that has fallen to Earth or exists in space is known as cosmic dust, sometimes known as extraterrestrial dust or space dust. The majority of particles of cosmic dust have sizes between a few molecules and 0.1 mm (100 µm). We refer to larger particles as meteorites. Cosmic dust is thought to be the remnants of asteroidal or cometary collisions that can be linked to collisions that took place during the Big Bang.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140768852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recurrent pregnancy loss, which affects 2%–5% of individuals, is just a significant concern for women's health. Uterine malformations, antiphospholipid syndrome, metabolic or endocrine diseases, as well as chromosomal abnormalities are among the often reported established reasons. Alternative aetiologies, like chronic uterine infections, hereditary thrombophilias, luteal stage insufficiency, or excessive male DNA disintegration rates, have been put forward yet remain regarded as debatable. The results for individuals who experience recurrent miscarriage had increased throughout time because to evidence-based therapies including surgical repair of chromosomal abnormalities, aspirin as well as anticoagulation in anticardiolipin disorder. About 50% of the instances, though, are still unsolved, so they are managed effectively with estrogen augmentation, anticoagulation, and/or immunostimulatory therapies. Regardless of the reason, couples who experience recurrent fetal death have a favourable long-term outlook and also the majority ultimately has a safe live delivery. Several miscarriages, though, may have a major psychological impact just on afflicted people, and numerous attempts are now being undertaken to enhance therapies or shorten the time it takes to conceive successfully. With an emphasis on inexplicable repeated fetal loss as well as the current usage of empiric therapies, this article reviews the recognised or contentious aetiologies as well as the suggested therapeutic approaches. As well, it covers the present use of pre - implantation genetic screening inside the treatment of repeated miscarriages.
2%-5%的女性会反复妊娠流产，这对女性健康来说是一个重大问题。子宫畸形、抗磷脂综合征、代谢或内分泌疾病以及染色体异常是经常报告的既定原因。也有人提出了其他病因，如慢性子宫感染、遗传性血栓性疾病、黄体功能不全或男性 DNA 分解率过高，但仍有待商榷。由于采用了循证疗法，包括染色体异常的手术修复、阿司匹林以及抗心磷脂紊乱的抗凝治疗等，反复流产患者的治疗效果不断提高。不过，约有 50%的情况仍未得到解决，因此需要通过雌激素增强、抗凝和/或免疫刺激疗法来有效控制。无论原因如何，反复出现胎儿死亡的夫妇的长期前景都很好，而且大多数人最终都能安全活产。不过，多次流产可能会对患者造成严重的心理影响，目前人们正在进行大量尝试，以加强疗法或缩短成功受孕所需的时间。本文以莫名其妙的反复流产以及目前使用的经验疗法为重点，回顾了公认的或有争议的病因以及建议的治疗方法。此外，文章还介绍了植入前基因筛查在治疗反复流产中的应用。
{"title":"Review Article: Early Recurrent Pregnancy Loss","authors":"Hiba Ahmed Suhail","doi":"10.55544/jrasb.3.1.51","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.51","url":null,"abstract":"Recurrent pregnancy loss, which affects 2%–5% of individuals, is just a significant concern for women's health. Uterine malformations, antiphospholipid syndrome, metabolic or endocrine diseases, as well as chromosomal abnormalities are among the often reported established reasons. Alternative aetiologies, like chronic uterine infections, hereditary thrombophilias, luteal stage insufficiency, or excessive male DNA disintegration rates, have been put forward yet remain regarded as debatable. The results for individuals who experience recurrent miscarriage had increased throughout time because to evidence-based therapies including surgical repair of chromosomal abnormalities, aspirin as well as anticoagulation in anticardiolipin disorder. About 50% of the instances, though, are still unsolved, so they are managed effectively with estrogen augmentation, anticoagulation, and/or immunostimulatory therapies. Regardless of the reason, couples who experience recurrent fetal death have a favourable long-term outlook and also the majority ultimately has a safe live delivery. Several miscarriages, though, may have a major psychological impact just on afflicted people, and numerous attempts are now being undertaken to enhance therapies or shorten the time it takes to conceive successfully. With an emphasis on inexplicable repeated fetal loss as well as the current usage of empiric therapies, this article reviews the recognised or contentious aetiologies as well as the suggested therapeutic approaches. As well, it covers the present use of pre - implantation genetic screening inside the treatment of repeated miscarriages.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Glucocorticoids are widely used for the suppression of inflammation in chronic inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease and autoimmune diseases, all of which are associated with increased expression of inflammatory genes. The molecular mechanisms involved in this anti-inflammatory action of glucocorticoids is discussed, particularly in asthma, which accounts for the highest clinical use of these agents. Glucocorticoids bind to glucocorticoid receptors in the cytoplasm which then dimerize and translocate to the nucleus, where they bind to glucocorticoid response elements (GRE) on glucocorticoid-responsive genes, resulting in increased transcription. Glucocorticoids may increase the transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase, but this is unlikely to account for all of the widespread anti-inflammatory actions of glucocorticoids.[3] The most striking effect of glucocorticoids is to inhibit the expression of multiple inflammatory genes.[3]
{"title":"Hydrocortisone as Antiallergic Drug","authors":"Salam Abed Muhammad","doi":"10.55544/jrasb.3.1.50","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.50","url":null,"abstract":"Glucocorticoids are widely used for the suppression of inflammation in chronic inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease and autoimmune diseases, all of which are associated with increased expression of inflammatory genes. The molecular mechanisms involved in this anti-inflammatory action of glucocorticoids is discussed, particularly in asthma, which accounts for the highest clinical use of these agents. \u0000Glucocorticoids bind to glucocorticoid receptors in the cytoplasm which then dimerize and translocate to the nucleus, where they bind to glucocorticoid response elements (GRE) on glucocorticoid-responsive genes, resulting in increased transcription. Glucocorticoids may increase the transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase, but this is unlikely to account for all of the widespread anti-inflammatory actions of glucocorticoids.[3] \u0000The most striking effect of glucocorticoids is to inhibit the expression of multiple inflammatory genes.[3]","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DNA Sequencing technologies have been in use since 1970 and has diversified to much more effective transformations till the date. Initially due to certain drawbacks like cost, time period and requirement of toxic and radioactive elements for the compilation of the process, it remained unintroduced to research setting for complex data in earlier times. One of a technique named as the Sanger technique had more practical approach for sequencing the desired data of the fragments. But the need of DNA sequencing surged after the commencement of the Human Genome Project (HGP) which was a 13 year long collaboration to sequence human genome for understanding its applicable uses.1 At the current stage, the progress moved towards Next Generation Sequencing (NGS) to sequence the fragments of DNA for a better acknowledgement but somehow this did not reported for a fair outcome for palindromic DNA while sequencing. In this rugged sequencing platforms, Roche’s 454 with emulsion PCR technique amplified the templates through beads which later went through pyrosequencing with DNA Polymerase gave the desired output but had a major drawback of high cost.2 Therefore, this study deals with effective PST – PCR technique for studying palindromic DNA in NGS and how it can be considered to fit in all advantages for the above task.
DNA 测序技术自 1970 年开始使用，时至今日已发展到更为有效的变革阶段。起初，由于成本高、耗时长、需要使用有毒和放射性元素等缺点，DNA 测序技术在早期并没有被引入到复杂数据的研究中。一种名为桑格（Sanger）技术的技术拥有更实用的方法，可以对所需数据的片段进行测序。但在人类基因组计划（HGP）启动后，对 DNA 测序的需求激增，该计划历时 13 年，旨在对人类基因组进行测序，以了解其适用用途1。在这种坚固耐用的测序平台中，罗氏公司的 454 采用乳液 PCR 技术，通过珠子扩增模板，然后用 DNA 聚合酶进行热测序，从而获得理想的结果，但其主要缺点是成本高昂。2 因此，本研究探讨了在 NGS 中研究回文 DNA 的有效 PST - PCR 技术，以及如何考虑将其所有优点都用于上述任务。
{"title":"NGS Technique for Palindromic Sequencing of DNA Through Effective PST-PCR","authors":"Prapti Saraswat","doi":"10.55544/jrasb.3.1.49","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.49","url":null,"abstract":"DNA Sequencing technologies have been in use since 1970 and has diversified to much more effective transformations till the date. Initially due to certain drawbacks like cost, time period and requirement of toxic and radioactive elements for the compilation of the process, it remained unintroduced to research setting for complex data in earlier times. One of a technique named as the Sanger technique had more practical approach for sequencing the desired data of the fragments. But the need of DNA sequencing surged after the commencement of the Human Genome Project (HGP) which was a 13 year long collaboration to sequence human genome for understanding its applicable uses.1\u0000At the current stage, the progress moved towards Next Generation Sequencing (NGS) to sequence the fragments of DNA for a better acknowledgement but somehow this did not reported for a fair outcome for palindromic DNA while sequencing. In this rugged sequencing platforms, Roche’s 454 with emulsion PCR technique amplified the templates through beads which later went through pyrosequencing with DNA Polymerase gave the desired output but had a major drawback of high cost.2 Therefore, this study deals with effective PST – PCR technique for studying palindromic DNA in NGS and how it can be considered to fit in all advantages for the above task.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Hamid Mohammadi, Yernazarova Aliya Kulakhmetovna, Reza Joia
As we all know, numerous methods have been invented for better managing of the reservoirs to recover the trapped oil from them as much as possible. These techniques included primary techniques that were implemented primarily at the beginning of this industry. As these techniques were not effective enough, secondary techniques, like; water flooding and gas injection methods were created and the amount of recovered oil were increased, as well. On the contrary, the demand for more oil was raised up and it was felt that much more effective techniques are necessary. It resulted to creation of Enhanced Oil Recovery Techniques and these techniques are included; thermal methods (steam injection, steam assisted gravity drainage and in-situ combustion), Chemical methods (alkali flooding, surfactant flooding, polymer flooding, foam flooding, and combination of alkali-surfactant-polymer flooding), and microbial EOR. The most promising technique is microbial EOR because of being cost-effective and ecofriendly. GEMEOR (Genetically Engineered MEOR) and EEOR (Enzyme Enhanced Oil Recovery) are two new trends of MEOR that own potential hopes in petroleum industry.
{"title":"An Overview of Oil Recovery Techniques: From Primary to Enhanced Oil Recovery Methods","authors":"Mohammad Hamid Mohammadi, Yernazarova Aliya Kulakhmetovna, Reza Joia","doi":"10.55544/jrasb.3.1.48","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.48","url":null,"abstract":"As we all know, numerous methods have been invented for better managing of the reservoirs to recover the trapped oil from them as much as possible. These techniques included primary techniques that were implemented primarily at the beginning of this industry. As these techniques were not effective enough, secondary techniques, like; water flooding and gas injection methods were created and the amount of recovered oil were increased, as well. On the contrary, the demand for more oil was raised up and it was felt that much more effective techniques are necessary. It resulted to creation of Enhanced Oil Recovery Techniques and these techniques are included; thermal methods (steam injection, steam assisted gravity drainage and in-situ combustion), Chemical methods (alkali flooding, surfactant flooding, polymer flooding, foam flooding, and combination of alkali-surfactant-polymer flooding), and microbial EOR. The most promising technique is microbial EOR because of being cost-effective and ecofriendly. GEMEOR (Genetically Engineered MEOR) and EEOR (Enzyme Enhanced Oil Recovery) are two new trends of MEOR that own potential hopes in petroleum industry.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background; Thyroid dysfunction has a substantial effect on the functioning of menstruation and the fertility of women. Hypothyroidism often coincides with increased prolactin levels, which worsens the disease. Research objectives; A cross-sectional study was undertaken in the infertility outpatient department of the University Teaching Hospital in Iraq, specifically examining the medical records of women who had undergone infertility evaluations. The study examined pertinent historical information, clinical observations, and findings from several investigations, such as thyroid function testing and blood prolactin level assessment. Descriptive and inferential statistical techniques were used to ascertain the prevalence and associations between predictors and outcome variables. Aim of the study; The objective of this study was to evaluate the prevalence of thyroid diseases among infertile women who are seeking treatment at the outpatient department of University Teaching Hospital in Iraq. Furthermore, it sought to examine the correlation between hypothyroidism and hyperprolactinemia with obesity, a subject that has not been thoroughly studied in our population. Novelty; Out of the 200 participants, the largest group, comprising 90 individuals (42%), were categorized as obese. The mean body mass index (BMI) of the subjects was 24 ± 4 kg/m2. The prevalence of thyroid disorder was 18%, with hypothyroidism representing 13% and hyperthyroidism representing 4%. No significant correlation was observed between BMI and hyperprolactinemia in people diagnosed with thyroid illness. Furthermore, no noteworthy correlation was found between BMI and hyperprolactinemia as an isolated condition. Nevertheless, a notable direct association was observed between thyroid stimulating hormone (TSH) and prolactin levels. Thyroid abnormalities and hyperprolactinemia are common in women who have difficulty getting pregnant. Therefore, it is advisable to regularly screen for these problems during the initial evaluation of infertility. While there was no notable association between BMI and thyroid illness and hyperprolactinemia, it is important to acknowledge the potential influence of weight gain on infertility, especially given that the majority of participants in the research were obese.
{"title":"The Effect of the Pituitary Gland on the Hormone Prolactin and Its Relationship to Menstrual Irregularity According to Obesity","authors":"Raghad Tahseen Thanoon, Takea Shaker Ahmed","doi":"10.55544/jrasb.3.1.47","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.47","url":null,"abstract":"Background; Thyroid dysfunction has a substantial effect on the functioning of menstruation and the fertility of women. Hypothyroidism often coincides with increased prolactin levels, which worsens the disease.\u0000Research objectives; A cross-sectional study was undertaken in the infertility outpatient department of the University Teaching Hospital in Iraq, specifically examining the medical records of women who had undergone infertility evaluations. The study examined pertinent historical information, clinical observations, and findings from several investigations, such as thyroid function testing and blood prolactin level assessment. Descriptive and inferential statistical techniques were used to ascertain the prevalence and associations between predictors and outcome variables.\u0000Aim of the study; The objective of this study was to evaluate the prevalence of thyroid diseases among infertile women who are seeking treatment at the outpatient department of University Teaching Hospital in Iraq. Furthermore, it sought to examine the correlation between hypothyroidism and hyperprolactinemia with obesity, a subject that has not been thoroughly studied in our population.\u0000Novelty; Out of the 200 participants, the largest group, comprising 90 individuals (42%), were categorized as obese. The mean body mass index (BMI) of the subjects was 24 ± 4 kg/m2. The prevalence of thyroid disorder was 18%, with hypothyroidism representing 13% and hyperthyroidism representing 4%. No significant correlation was observed between BMI and hyperprolactinemia in people diagnosed with thyroid illness. Furthermore, no noteworthy correlation was found between BMI and hyperprolactinemia as an isolated condition. Nevertheless, a notable direct association was observed between thyroid stimulating hormone (TSH) and prolactin levels. Thyroid abnormalities and hyperprolactinemia are common in women who have difficulty getting pregnant. Therefore, it is advisable to regularly screen for these problems during the initial evaluation of infertility. While there was no notable association between BMI and thyroid illness and hyperprolactinemia, it is important to acknowledge the potential influence of weight gain on infertility, especially given that the majority of participants in the research were obese.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nasal drug delivery has received a great deal of attention as a convenient, reliable, and promising method for the systemic administration of drugs. It is especially for those molecules which are ineffective orally and only effective if administered by injection. The nasal route of drug delivery has advantages over the other alternative systems of non-invasive drug administration. The present review is an attempt to provide some information concerning nasal drug delivery system such as limitations, advantages, mechanism of drug absorption, anatomy of nasal cavity, factors affecting of nasal drug delivery, strategies to enhance nasal absorption, strategies to extend duration of drug formulations within the nasal cavity, leading to improved nasal drug absorption, novel drug formulations, sorts of nasal drug delivery system with uses of nasal drug delivery in various diseases, and recent advancement of nasal delivery systems.
{"title":"Review on Nasal Drug Delivery System and Their Application","authors":"Kanchan Tariyal","doi":"10.55544/jrasb.3.1.46","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.46","url":null,"abstract":"Nasal drug delivery has received a great deal of attention as a convenient, reliable, and promising method for the systemic administration of drugs. It is especially for those molecules which are ineffective orally and only effective if administered by injection. The nasal route of drug delivery has advantages over the other alternative systems of non-invasive drug administration. The present review is an attempt to provide some information concerning nasal drug delivery system such as limitations, advantages, mechanism of drug absorption, anatomy of nasal cavity, factors affecting of nasal drug delivery, strategies to enhance nasal absorption, strategies to extend duration of drug formulations within the nasal cavity, leading to improved nasal drug absorption, novel drug formulations, sorts of nasal drug delivery system with uses of nasal drug delivery in various diseases, and recent advancement of nasal delivery systems.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140231261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The systematic study was carried out to determine the physico-chemical parameters of water samples of Ramganga River in Bareilly district. The rivers are an essential water resource and used for several purposes. The water quality of all fresh water ecosystems is assessed by the physico-chemical. Water samples were collected from 3 sites along the river and analyzed using standard methods in laboratory. The physico-chemical characteristics were studied and analyzed for a period of 6 months from April 2022 to September 2022. Various physico-chemical parameters such as Temperature, PH, transparency, total dissolved solids, total suspended solids, DO, FCO2, Carbonates, Bicarbonates, chlorides, Calcium, Magnesium, Total hardness of lake were estimated throughout the year.
{"title":"Analysis of Physico-Chemical Factors of Ramganga River Water in Bareilly District","authors":"Sunil Kumar, Vikas Jain","doi":"10.55544/jrasb.3.1.45","DOIUrl":"https://doi.org/10.55544/jrasb.3.1.45","url":null,"abstract":"The systematic study was carried out to determine the physico-chemical parameters of water samples of Ramganga River in Bareilly district. The rivers are an essential water resource and used for several purposes. The water quality of all fresh water ecosystems is assessed by the physico-chemical. Water samples were collected from 3 sites along the river and analyzed using standard methods in laboratory. The physico-chemical characteristics were studied and analyzed for a period of 6 months from April 2022 to September 2022. Various physico-chemical parameters such as Temperature, PH, transparency, total dissolved solids, total suspended solids, DO, FCO2, Carbonates, Bicarbonates, chlorides, Calcium, Magnesium, Total hardness of lake were estimated throughout the year.","PeriodicalId":507877,"journal":{"name":"Journal for Research in Applied Sciences and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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