Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.05.017
John M. Burnheimer , Dylan J. Baxter , Kathleen B. Deeley , Alexandre R. Vieira , Mariana Bezamat
Introduction
External apical root resorption (EARR) is often an undesirable sequela of orthodontic treatment. Prior studies have suggested a substantial link between EARR and certain genetic components. Single nucleotide polymorphisms (SNPs) may play a role as predisposing factors. This study aimed to investigate the potential association between EARR and various SNPs.
Methods
The study included 218 orthodontic participants of all malocclusions who had available pretreatment and posttreatment panoramic radiographs. The most severely affected maxillary incisor on the radiograph was assessed for EARR using a 0-4 categorical scale. DNA was taken from the saliva samples of the participants, and the SNPs were analyzed using polymerase chain reaction and TaqMan chemistry. Statistical testing was performed to verify any associations with EARR (P <0.05).
Results
From all genes tested, the rs678397 SNP of ACT3N (P = 0.003) and the rs1051771 SNP of TSC2 (P = 0.03) were significantly associated with EARR. No association could be established between other polymorphisms and EARR. In addition, patients with Class III malocclusion and extended treatment times were at increased risk of developing EARR.
Conclusions
Our results support the concept of gene polymorphisms as risk factors in EARR. In particular, a significant association was found between ACT3N and TSC2 and EARR. Clinically, predisposing risk factors for EARR should be assessed for each patient.
{"title":"Exploring etiologic contributions to the occurrence of external apical root resorption","authors":"John M. Burnheimer , Dylan J. Baxter , Kathleen B. Deeley , Alexandre R. Vieira , Mariana Bezamat","doi":"10.1016/j.ajodo.2024.05.017","DOIUrl":"10.1016/j.ajodo.2024.05.017","url":null,"abstract":"<div><h3>Introduction</h3><div><span><span><span>External apical root resorption (EARR) is often an undesirable </span>sequela of </span>orthodontic treatment. Prior studies have suggested a substantial link between EARR and certain genetic components. </span>Single nucleotide polymorphisms (SNPs) may play a role as predisposing factors. This study aimed to investigate the potential association between EARR and various SNPs.</div></div><div><h3>Methods</h3><div><span><span><span>The study included 218 orthodontic participants of all </span>malocclusions who had available pretreatment and posttreatment </span>panoramic radiographs<span>. The most severely affected maxillary incisor<span> on the radiograph was assessed for EARR using a 0-4 categorical scale. DNA was taken from the saliva samples of the participants, and the SNPs were analyzed using polymerase chain reaction and TaqMan chemistry. Statistical testing was performed to verify any associations with EARR (</span></span></span><em>P</em> <0.05).</div></div><div><h3>Results</h3><div>From all genes tested, the rs678397 SNP of <em>ACT3N</em> (<em>P</em> = 0.003) and the rs1051771 SNP of <em>TSC2</em> (<em>P</em><span> = 0.03) were significantly associated with EARR. No association could be established between other polymorphisms and EARR. In addition, patients with Class III malocclusion and extended treatment times were at increased risk of developing EARR.</span></div></div><div><h3>Conclusions</h3><div><span>Our results support the concept of gene polymorphisms as risk factors in EARR. In particular, a significant association was found between </span><em>ACT3N</em> and <em>TSC2</em> and EARR. Clinically, predisposing risk factors for EARR should be assessed for each patient.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 356-362.e8"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141604491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.06.008
Nancy Rajan, Tony Weir, Maurice J. Meade
Introduction
This study aimed to investigate whether there was a difference between the planned and achieved lingual root torque of the maxillary central incisors in patients treated with an initial series of Invisalign (Align Technology, Santa Clara, Calif) aligners in which >10° change in the inclination of these teeth was prescribed via the ClinCheck facility.
Methods
The pretreatment, planned, and the digital models after wear of the initial series of aligners regarding adult patients who satisfied selection criteria and were treated using the Invisalign appliance were measured using the Geomagic Control X software (version 2017.0.3; 3D systems, Rock Hill, SC).
Results
A sample of 63 patients with 126 maxillary central incisors satisfied the inclusion criteria. The mean accuracy of the planned torque change of the maxillary central incisors that was achieved was 41.9%. A clinically significant shortfall (≥5°) was detected in 78.6% of the incisors, with the majority showing an underexpression between 10°-15°. Linear regression analyses indicated that weekly or biweekly wear protocols or the presence or absence of power ridges did not influence the accuracy of planned torque expression (P >0.05).
Conclusions
The changes in torque expression with an initial series of Invisalign aligners were less than half of what was planned in patients in which at least a 10° change in lingual root torque of these teeth was prescribed. The presence of power ridges and the aligner change protocol did not appear to significantly affect the accuracy of maxillary central incisor torque expression.
前言:本研究旨在调查通过 ClinCheck 设备进行初始系列隐适美(Align Technology, Santa Clara, Calif)矫治器治疗的患者,其上颌中切牙倾斜度变化大于 10° 时,计划的上颌中切牙舌根扭力与实现的上颌中切牙舌根扭力之间是否存在差异:使用 Geomagic Control X 软件(2017.0.3 版;3D systems,Rock Hill,SC)对符合选择标准并使用隐适美(Invisalign)矫治器进行治疗的成年患者的预处理、计划和佩戴初始系列矫治器后的数字模型进行测量:符合纳入标准的上颌中切牙患者有 63 人,共 126 颗。上颌中切牙计划扭矩变化的平均准确率为 41.9%。在 78.6% 的切牙中发现了临床意义上的明显不足(≥5°),大多数切牙的不足程度在 10°-15° 之间。线性回归分析表明,每周或每两周戴牙一次、有无动力脊并不影响计划扭矩表达的准确性(P >0.05):结论:在对这些牙齿的舌根扭力至少有10°变化的患者中,初始系列隐适美矫正器的扭力变化不到计划的一半。动力脊的存在和矫治器更换方案似乎对上颌中切牙扭力表达的准确性没有显著影响。
{"title":"Efficacy of planned moderate to severe torque changes in maxillary central incisors with the Invisalign appliance: A retrospective investigation","authors":"Nancy Rajan, Tony Weir, Maurice J. Meade","doi":"10.1016/j.ajodo.2024.06.008","DOIUrl":"10.1016/j.ajodo.2024.06.008","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to investigate whether there was a difference between the planned and achieved lingual root torque of the maxillary central incisors in patients treated with an initial series of Invisalign (Align Technology, Santa Clara, Calif) aligners in which >10° change in the inclination of these teeth was prescribed via the ClinCheck facility.</div></div><div><h3>Methods</h3><div>The pretreatment, planned, and the digital models after wear of the initial series of aligners regarding adult patients who satisfied selection criteria and were treated using the Invisalign appliance were measured using the Geomagic Control X software (version 2017.0.3; 3D systems, Rock Hill, SC).</div></div><div><h3>Results</h3><div>A sample of 63 patients with 126 maxillary central incisors satisfied the inclusion criteria. The mean accuracy of the planned torque change of the maxillary central incisors that was achieved was 41.9%. A clinically significant shortfall (≥5°) was detected in 78.6% of the incisors, with the majority showing an underexpression between 10°-15°. Linear regression analyses indicated that weekly or biweekly wear protocols or the presence or absence of power ridges did not influence the accuracy of planned torque expression (<em>P</em> >0.05).</div></div><div><h3>Conclusions</h3><div>The changes in torque expression with an initial series of Invisalign aligners were less than half of what was planned in patients in which at least a 10° change in lingual root torque of these teeth was prescribed. The presence of power ridges and the aligner change protocol did not appear to significantly affect the accuracy of maxillary central incisor torque expression.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 375-383"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/S0889-5406(24)00354-8
{"title":"Information for readers","authors":"","doi":"10.1016/S0889-5406(24)00354-8","DOIUrl":"10.1016/S0889-5406(24)00354-8","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Page A8"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142423314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.06.015
Rolf G. Behrents , Jae Hyun Park
{"title":"Journal statistics and backlog issues","authors":"Rolf G. Behrents , Jae Hyun Park","doi":"10.1016/j.ajodo.2024.06.015","DOIUrl":"10.1016/j.ajodo.2024.06.015","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 301-303"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.05.018
Maurice J. Meade , Brianna Poirier , Emilija D. Jensen
Introduction
Patients seeking health information on the Internet is commonplace. This scoping review aimed to collate and synthesize the evidence regarding the quality of Web-based orthodontic information.
Methods
A systematic search and independent screening process was conducted by 2 independent reviewers across 4 databases. The review was conducted in alignment with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines.
Results
Of 661 records identified, 30 publications satisfied the inclusion criteria. Reviewed studies included those related to the information contained within Web sites regarding dental and orthodontist practices, orthodontic interventions, appliances and auxiliaries, orthodontic conditions commonly requiring orthodontic therapy, issues related to patient experience, and advice during orthodontic treatment. A total of 5 quality of information (QOI) instruments and 3 readability tools were employed, with the University of Oxford, United Kingdom (DISCERN) instrument and the Flesch Reading Ease Score tool being the most frequently used. Most studies determined that the QOI contained within evaluated Web sites was poor and provided suboptimal information related to treatment risks and Web site reliability. Most studies indicated that the information was more difficult to read than recommended by guidelines.
Conclusions
The QOI of orthodontic information available on Web sites was low to moderate, with the readability of content at a level that was considered challenging for many readers to understand. A recommendation for greater involvement of the dental and orthodontic specialty in Web site development was commonplace. Research is required for the development of validated tools that can determine the accuracy of information in addition to Web site reliability.
{"title":"The quality of Web-based orthodontic information: A scoping review","authors":"Maurice J. Meade , Brianna Poirier , Emilija D. Jensen","doi":"10.1016/j.ajodo.2024.05.018","DOIUrl":"10.1016/j.ajodo.2024.05.018","url":null,"abstract":"<div><h3>Introduction</h3><div>Patients seeking health information on the Internet is commonplace. This scoping review aimed to collate and synthesize the evidence regarding the quality of Web-based orthodontic information.</div></div><div><h3>Methods</h3><div>A systematic search and independent screening process was conducted by 2 independent reviewers across 4 databases. The review was conducted in alignment with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines.</div></div><div><h3>Results</h3><div>Of 661 records identified, 30 publications satisfied the inclusion criteria. Reviewed studies included those related to the information contained within Web sites regarding dental and orthodontist practices, orthodontic interventions, appliances and auxiliaries, orthodontic conditions commonly requiring orthodontic therapy, issues related to patient experience, and advice during orthodontic treatment. A total of 5 quality of information (QOI) instruments and 3 readability tools were employed, with the University of Oxford, United Kingdom (DISCERN) instrument and the Flesch Reading Ease Score tool being the most frequently used. Most studies determined that the QOI contained within evaluated Web sites was poor and provided suboptimal information related to treatment risks and Web site reliability. Most studies indicated that the information was more difficult to read than recommended by guidelines.</div></div><div><h3>Conclusions</h3><div>The QOI of orthodontic information available on Web sites was low to moderate, with the readability of content at a level that was considered challenging for many readers to understand. A recommendation for greater involvement of the dental and orthodontic specialty in Web site development was commonplace. Research is required for the development of validated tools that can determine the accuracy of information in addition to Web site reliability.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 313-329"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.07.009
Jadbinder Seehra , Nikolaos Pandis
{"title":"To dichotomize or not dichotomize a continuous predictor","authors":"Jadbinder Seehra , Nikolaos Pandis","doi":"10.1016/j.ajodo.2024.07.009","DOIUrl":"10.1016/j.ajodo.2024.07.009","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 406-407"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.07.005
Laurance Jerrold
{"title":"When history needs to be ignored","authors":"Laurance Jerrold","doi":"10.1016/j.ajodo.2024.07.005","DOIUrl":"10.1016/j.ajodo.2024.07.005","url":null,"abstract":"","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 404-405"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ajodo.2024.05.014
Introduction
This study aimed to evaluate the effectiveness of Dental Monitoring (DM) (Dental Monitoring SAS, Paris, France) compared with conventional monitoring (CM) during active orthodontic treatment.
Methods
The Peer Assessment Rating (PAR) index was used to evaluate the pretreatment and posttreatment records of 51 patients, with 26 in the CM group and 25 in the DM group. The change in weighted PAR was analyzed to assess the effectiveness of treatment.
Results
The chi-square test revealed that the CM group had a higher percentage of patients in the great improvement category compared with the DM group. However, this difference was not statistically significant (P = 0.192). A repeated measures general linear model demonstrated significant improvement over time (P <0.001), with no statistically significant group differences noted between CM and DM (P = 0.181) and no statistically significant time-by-group interaction (P = 0.299).
Conclusions
Both CM and DM showed significant improvements in weighted PAR scores, but no statistically significant difference is present between the 2 groups.
{"title":"Evaluating Dental Monitoring effectiveness compared with conventional monitoring of clear aligner therapy using the Peer Assessment Rating index","authors":"","doi":"10.1016/j.ajodo.2024.05.014","DOIUrl":"10.1016/j.ajodo.2024.05.014","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate the effectiveness of Dental Monitoring (DM) (Dental Monitoring SAS, Paris, France) compared with conventional monitoring (CM) during active orthodontic treatment.</div></div><div><h3>Methods</h3><div>The Peer Assessment Rating (PAR) index was used to evaluate the pretreatment and posttreatment records of 51 patients, with 26 in the CM group and 25 in the DM group. The change in weighted PAR was analyzed to assess the effectiveness of treatment.</div></div><div><h3>Results</h3><div>The chi-square test revealed that the CM group had a higher percentage of patients in the great improvement category compared with the DM group. However, this difference was not statistically significant (<em>P</em> = 0.192). A repeated measures general linear model demonstrated significant improvement over time (<em>P</em> <0.001), with no statistically significant group differences noted between CM and DM (<em>P</em> = 0.181) and no statistically significant time-by-group interaction (<em>P</em> = 0.299).</div></div><div><h3>Conclusions</h3><div>Both CM and DM showed significant improvements in weighted PAR scores, but no statistically significant difference is present between the 2 groups.</div></div>","PeriodicalId":50806,"journal":{"name":"American Journal of Orthodontics and Dentofacial Orthopedics","volume":"166 4","pages":"Pages 350-355"},"PeriodicalIF":2.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}