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Prospective assessment of functional and clinical results of surgical patellar stabilization in rural and urban populations. Equal chance to success? 对城乡居民髌骨稳定手术的功能和临床效果进行前瞻性评估。成功机会均等?
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-03-25 Epub Date: 2024-01-29 DOI: 10.26444/aaem/178137
Jacek Walawski, Oliwer Sygacz, Martyna Jarocka, Tomasz Sacewicz

Introduction and objective: Patella dislocation represents 3.3% of all knee injuries often leading to persistent instability. Medial patello-femoral ligament(MPFL) reconstruction is the standard method of treatment in the patellar instability. Rehabilitation after MPFL-R is a long and demanding procedure. The hypothesis presented reflects the idea that despite relatively good access to hospital care and surgical options, the post-operative rehabilitation care system is still inferior in rural areas versus the one offered in major cities and towns.

Material and methods: Between January 2015 - January 2018, 47 patients met the study inclusion criteria, diagnosed and operated on due to patellar instability. 8 patients were lost for full follow-up. Finally, 39 patients were included, divided into two groups - group A (19 from cities), group B (20 from rural area). Prospective KOOS and Kujala scales assessments were conducted: preoperative, 6 and 12 months after surgery. Knee isokinetic muscle strength was measured at 3 stages; prior to surgery, 6 and 12 months after reconstruction.

Results: All patients showed significant improvement measured in the KOOS and Kujala scales after the procedure, compared to the pre-operational results. Despite equal clinical improvement, patients from Group A(city) achieved better functional outcomes as presented in the results of knee extensor functional tests using a Biodex dynamometer.

Conclusions: Rehabilitation after MPFL reconstruction improves muscle strength and clinical outcome. Patients from rural areas had inferior functional results in comparison to the patients from major cities, even 12 months after surgical patella stabilization. Despite the development of roads and transport according to the EU cohesion policy, there are still differences in rehabilitation results between rural and city areas.

引言和目的:髌骨脱位占膝关节损伤总数的 3.3%,通常会导致持续性不稳定。髌骨-股内侧韧带(MPFL)重建是治疗髌骨不稳的标准方法。MPFL-R术后康复是一个漫长而艰巨的过程。本文提出的假设反映了这样一种观点,即尽管医院护理和手术选择相对较好,但农村地区的术后康复护理系统仍不如大城市和城镇:2015 年 1 月至 2018 年 1 月间,47 名患者符合研究纳入标准,因髌骨不稳而被诊断并接受手术。8名患者失去了全面随访的机会。最后,39 名患者被纳入研究,分为两组--A 组(19 名来自城市)和 B 组(20 名来自农村)。分别在术前、术后 6 个月和 12 个月进行了前瞻性 KOOS 和 Kujala 量表评估。在手术前、重建后 6 个月和 12 个月的三个阶段测量了膝关节等速肌力:结果:与术前结果相比,所有患者术后的 KOOS 和 Kujala 量表均有明显改善。尽管临床改善程度相同,但A组(城市)患者在使用Biodex测力计进行的膝关节伸肌功能测试结果中获得了更好的功能结果:结论:MPFL重建术后的康复治疗可改善肌肉力量和临床效果。结论:MPFL 重建后的康复治疗可提高肌肉力量和临床疗效。与来自大城市的患者相比,来自农村地区的患者即使在手术稳定髌骨 12 个月后,其功能效果也不如来自大城市的患者。尽管根据欧盟团结政策发展了道路和交通,但农村和城市地区的康复效果仍存在差异。
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引用次数: 0
Occurrence of Dermacentor reticulatus in central-southern Poland, and potential threats to human and animal health. Dermacentor reticulatus 在波兰中南部的出现以及对人类和动物健康的潜在威胁。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-03-25 Epub Date: 2024-01-30 DOI: 10.26444/aaem/178401
Alicja Buczek, Weronika Buczek, Maciej Rudek, Marek Asman, Magdalena Świsłocka, Katarzyna Bartosik

Introduction and objective: Dermacentor reticulatus is one of the tick species of the greatest epidemiological importance in Europe. To date, the Eastern European and Western European populations of this tick species have been separated by an area located in Poland where the species has never been found. In this study, newly discovered D. reticulatus localities in areas transformed by human activities in central-southern Poland are described.

Material and methods: The specimens of the ornate dog tick were identified among ticks collected from companion animals in 2010, 2012, 2013, and 2014. They were examined using PCR methods to detect Borrelia burgdorferi s.l., Rickettsia spp., Anaplasma phagocytophilum, Bartonella spp., Babesia spp., and Toxoplasma gondii. In the case of the positive results, the amplicons were sequenced and examined by a BLAST search.

Results: In total, 6 specimens of D. reticulatus were collected (3 females and 3 males). As declared by the owners, animal hosts stayed in the same area throughout the study period and had never travelled outside their place of residence. As many as 3/6 (50%) of D. reticulatus adults removed from dogs were infected with Rickettsia raoultii.

Conclusions: The results expand the available data on the spread of the ornate dog tick and indicate that, since 2010, this tick species and Rickettsia raoultii transmitted by this tick species have probably been present in this area, which has a strongly transformed agricultural structure and and had previously been regarded as a D. reticulatus-free zone. The presence of the ornate dog tick in urban and suburban habitats in central-southern Poland poses new threats to the health of companion animals and humans associated with the transmission of pathogens by this species.

引言和目的:网斑蜱(Dermacentor reticulatus)是欧洲流行病学上最重要的蜱类之一。迄今为止,这种蜱虫的东欧种群和西欧种群一直被位于波兰的一个从未发现过这种蜱虫的地区分隔开来。本研究描述了在波兰中南部因人类活动而改变的地区新发现的 D. reticulatus:2010 年、2012 年、2013 年和 2014 年从伴侣动物身上采集的蜱虫中鉴定出了华丽狗蜱标本。使用 PCR 方法对这些标本进行了检测,以发现博氏杆菌、立克次体、噬细胞嗜血杆菌、巴顿氏菌、巴贝斯菌和弓形虫。对于阳性结果,对扩增子进行了测序,并通过 BLAST 搜索进行了检验:共采集到 6 个 D. reticulatus 标本(3 个雌性和 3 个雄性)。根据动物主人的申报,动物宿主在整个研究期间都待在同一地区,从未离开过居住地。从狗身上取出的网斑立克次体成虫中有3/6(50%)感染了Rickettsia raoultii:结论:研究结果扩大了有关华丽狗蜱传播的现有数据,并表明自 2010 年以来,该蜱种和由该蜱种传播的 Rickettsia raoultii 很可能已在该地区出现。波兰中南部城市和郊区栖息地出现的华丽狗蜱对伴侣动物和人类的健康构成了新的威胁,这与该物种传播病原体有关。
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引用次数: 0
Registered incidence of acute upper respiratory tract infections diagnosed by primary care physicians in Poland - 5-year retrospective analysis of the national health insurance database. 波兰初级保健医生诊断的急性上呼吸道感染登记发病率--对国家医疗保险数据库的五年回顾性分析。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-03-25 Epub Date: 2024-03-04 DOI: 10.26444/aaem/183993
Iwona Paciepnik, Agata Bąk, Katarzyna Leoszkiewicz, Adam Windak, Tomasz Madej, Oleszczyk Marek, Krzysztof Studziński, Tomasz Tomasik

Introduction and objective: Upper respiratory tract infection (URTIs), caused by a variety of viruses and sometimes by bacteria, represents the most common acute illness in primary health care. The aim of the study was to explore the registered incidence of URTIs in Poland in the period between 2015-2019, and its burden on the health care system.

Material and methods: A retrospective analysis was carried out of all medical encounters in Poland registered within the national billing database of public healthcare services. Medical services provided due to acute URTIs were classified according to the ICD-10 codes. Registered Incidence Rate (RIR) was calculated yearly, in a 100,000 population. A generalised additive model was used to calculate the Incidence Rate Ratio (IRR).

Results: In the analysed 5-year period, acute URTI was diagnosed in 24.3 million patients (61.7% of the whole population registered in PHC). The RIR of all acute URTIs in PHC was 50,762/100,000/year. Nearly 99% of consultations in this group of patients were provided by PHC physicians. Only 0.8% were referred to an OSC consultation and 0.4% were hospitalised. In PHC, indeterminate URTIs were most frequently diagnosed. The estimated IRR for children aged 1-4 years was 1.65 (95% CI: 1.64; 1.66, p<0.01) and for men 0.79 (95% CI: 0.79; 0.79; p<0.01). In the studied period, the number of patients consulted for acute URTI decreased slightly in PHC, but significantly in specialist services.

Conclusions: The registered incidence of URTIs in Poland burdens mainly PHC physicians. Women and children aged 1-4 years are more frequent users of medical services related to URTIs. It appears that strategies for increasing patient empowerment to provide efficient self-care reducing the utilisation of PHC services are needed.

导言和目的:上呼吸道感染(URTIs)由多种病毒引起,有时也由细菌引起,是初级卫生保健中最常见的急性疾病。本研究旨在探讨 2015-2019 年期间波兰登记的 URTI 发病率及其对医疗保健系统造成的负担:对波兰公共医疗保健服务国家计费数据库中登记的所有医疗事件进行了回顾性分析。因急性尿路感染而提供的医疗服务根据 ICD-10 编码进行分类。每年以 10 万人口为单位计算登记发病率 (RIR)。采用广义相加模型计算发病率比(IRR):在分析的 5 年期间,有 2430 万名患者(占初级保健中心登记人口总数的 61.7%)被诊断为急性尿路感染。在初级保健中心就诊的所有急性尿路感染患者中,发病率为 50,762 例/100,000 人/年。这组患者中近 99% 的咨询由初级保健中心的医生提供。只有0.8%的患者被转诊到门诊部就诊,0.4%的患者住院治疗。在初级保健中心,不确定的尿路感染最常被诊断出来。1-4岁儿童的估计IRR为1.65(95% CI:1.64;1.66,p结论:波兰登记的尿路感染发病率主要给初级保健医生带来了负担。妇女和 1-4 岁儿童更经常使用与尿路感染相关的医疗服务。看来有必要制定战略,增强患者的能力,使其能够提供高效的自我护理,从而减少对初级保健服务的使用。
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引用次数: 0
Analysis of functional efficiency and risk of falls in patients with different types of dementia - preliminary observations. 不同类型痴呆症患者的功能效率和跌倒风险分析--初步观察。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-03-25 Epub Date: 2023-07-18 DOI: 10.26444/aaem/168787
Magdalena Zawadzka, Joanna Kozłowska, Ewelina Ejchman-Pac, Gabriela Henrykowska, Małgorzata Lewicka

Introduction and objective: Dementia is a multifactorial neurological disease that affects 50 million people worldwide. It is a disorder that impairs cognitive functions, functional efficiency, balance and gait. It contributes to an increased risk of falls, reduces independence in everyday activities and deepens disability. The aim of the study was to investigate the correlation between dementia and independence related to functional efficiency and risk of falls in the elderly.

Material and methods: The eligibility criterion for participation in the study was age over 60, the presence of cognitive disorders, including dementia, and the ability to move with the use of orthopaedic equipment or independently. A total of 51 people participated in the study, including 13 people who underwent rehabilitation procedures. Each subject was evaluated once for cognitive abilities using two types of tests: the ADL scale, MMSE (Mini-Mental state Examination) and three physical fitness tests: SPPB (Short Physical Performance Battery), TUG (Timed Up & Go) and FRT (Functional Reach Test).

Results: The average score of the MMSE test was 13.29±6.23 points, the average of the ADL scale was 4.20±1.23 points. A positive correlation was found between the level of dementia and the independence of the examined person, as well as a positive relationship between the MMSE test and the result of the Functional Reach Test, and the relationship between the ADL scale and the SPPB and 'Get-Up and Go' tests.

Conclusions: It has been demonstrated inter alia that static balance and functional efficiency depends on the patient's independence in everyday activities, and the level of dementia may suggest the patient's dynamic balance. In addition, the need for a broader analysis of targeted studies was recognized to confirm the conclusions obtained.

导言和目的:痴呆症是一种多因素神经系统疾病,影响着全球 5000 万人。它是一种损害认知功能、功能效率、平衡和步态的疾病。它增加了跌倒的风险,降低了日常活动的独立性,并加深了残疾程度。本研究旨在调查老年痴呆症与老年人功能效率和跌倒风险相关的独立性之间的相关性:参与研究的资格标准是年龄超过 60 岁、存在认知障碍(包括痴呆症)以及能够借助矫形设备或独立移动。共有 51 人参与了研究,其中 13 人接受了康复治疗。每位受试者都接受了一次认知能力评估,评估使用两种测试:ADL量表、MMSE(迷你精神状态检查)和三种体能测试:结果:MMSE测试的平均得分为(13.29±6.23)分,ADL量表的平均得分为(4.20±1.23)分。痴呆程度与受检者的独立性之间呈正相关,MMSE 测试与功能性前伸测试结果之间呈正相关,ADL 量表与 SPPB 和 "起立和行走 "测试之间呈正相关:结论:研究表明,静态平衡和功能效率取决于患者在日常活动中的独立性,而痴呆程度可能会影响患者的动态平衡。此外,还认识到有必要对有针对性的研究进行更广泛的分析,以确认所获得的结论。
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引用次数: 0
Red LED light therapy for telogen effluvium in the course of long COVID in patients with and without androgenetic alopecia 红光 LED 光疗法治疗雄激素性脱发和非雄激素性脱发患者长 COVID 过程中的毛囊性脱发
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-01-08 DOI: 10.26444/aaem/177238
A. Gerkowicz, J. Bartosińska, P. Krakowski, R. Karpiński, D. Krasowska, Dorota Raczkiewicz, Mirosław Kwaśny, Dorota Krasowska
Introduction and Objective . Photobiomodulation with the use of light-emitting diodes (LEDs) seems to be a promising option for long COVID. This retrospective study evaluates the efficiency of LED irradiation in the treatment of TE in the course of long COVID in patients with and without androgenetic alopecia. Materials and methods. A retrospective single-centre chart review of patients with post-COVID hair loss was performed. 140 patients enrolled to the study were divided into four groups depending on the type of alopecia and treatment: 1) telogen effluvium with LED therapy (TE LED+), 2) telogen effluvium without LED therapy (TE LED-), 3) telogen effluvium and androgenetic alopecia with LED therapy (TE+AGA LED+), and 4) telogen effluvium and androgenetic alopecia without LED therapy (TE+AGA LED-). Clinical and trichoscopic parameters were compared. Results . After 12 weeks, cessation of hair loss and a negative hair pull test were more common in TE LED+ and TE+AGA LED+ in comparison to the patients without LED therapy (p<0.001, p=0.035, respectively). An increased number of thick hairs and an increased number of hairs within follicular units were more common in patients treated with LED irradiation, regardless of the type of alopecia, compared to the patients without LED therapy. Conclusions . The study revealed that LED therapy is safe, well tolerated and seems to be a promising therapeutic option for TE in patients with long COVID. It can be used as adjuvant therapy leading to faster reduction of hair loss, enhancing hair regrowth as well as hair shaft thickness and density.
引言和目的 .使用发光二极管(LED)进行光生物调制似乎是治疗长COVID的一种很有前景的方法。这项回顾性研究评估了 LED 照射治疗 TE 在雄激素性脱发患者和非雄激素性脱发患者长 COVID 病程中的疗效。材料与方法。该研究对 COVID 后脱发患者进行了回顾性单中心病历审查。根据脱发类型和治疗方法将 140 名患者分为四组:1) 毛囊性脱发,采用LED疗法(TE LED+);2) 毛囊性脱发,不采用LED疗法(TE LED-);3) 毛囊性脱发和雄激素性脱发,采用LED疗法(TE+AGA LED+);4) 毛囊性脱发和雄激素性脱发,不采用LED疗法(TE+AGA LED-)。比较了临床和毛囊镜参数。结果 .12 周后,与未接受 LED 治疗的患者相比,TE LED+ 和 TE+AGA LED+ 的脱发停止率和头发拉力测试阴性率更高(分别为 p<0.001 和 p=0.035)。与未接受 LED 治疗的患者相比,无论脱发类型如何,接受 LED 照射治疗的患者中,毛囊单位内粗毛发数量增加和毛囊单位内毛发数量增加的情况更常见。结论 .研究表明,LED疗法安全、耐受性好,似乎是治疗长COVID患者TE的一种很有前途的疗法。它可作为辅助疗法使用,能更快地减少脱发,促进头发再生,增加发干厚度和密度。
{"title":"Red LED light therapy for telogen effluvium in the course of long COVID in patients with and without androgenetic alopecia","authors":"A. Gerkowicz, J. Bartosińska, P. Krakowski, R. Karpiński, D. Krasowska, Dorota Raczkiewicz, Mirosław Kwaśny, Dorota Krasowska","doi":"10.26444/aaem/177238","DOIUrl":"https://doi.org/10.26444/aaem/177238","url":null,"abstract":"Introduction and Objective . Photobiomodulation with the use of light-emitting diodes (LEDs) seems to be a promising option for long COVID. This retrospective study evaluates the efficiency of LED irradiation in the treatment of TE in the course of long COVID in patients with and without androgenetic alopecia. Materials and methods. A retrospective single-centre chart review of patients with post-COVID hair loss was performed. 140 patients enrolled to the study were divided into four groups depending on the type of alopecia and treatment: 1) telogen effluvium with LED therapy (TE LED+), 2) telogen effluvium without LED therapy (TE LED-), 3) telogen effluvium and androgenetic alopecia with LED therapy (TE+AGA LED+), and 4) telogen effluvium and androgenetic alopecia without LED therapy (TE+AGA LED-). Clinical and trichoscopic parameters were compared. Results . After 12 weeks, cessation of hair loss and a negative hair pull test were more common in TE LED+ and TE+AGA LED+ in comparison to the patients without LED therapy (p<0.001, p=0.035, respectively). An increased number of thick hairs and an increased number of hairs within follicular units were more common in patients treated with LED irradiation, regardless of the type of alopecia, compared to the patients without LED therapy. Conclusions . The study revealed that LED therapy is safe, well tolerated and seems to be a promising therapeutic option for TE in patients with long COVID. It can be used as adjuvant therapy leading to faster reduction of hair loss, enhancing hair regrowth as well as hair shaft thickness and density.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"56 8","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139447877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge, attitudes, and practices towards COVID-19 and COVID-19 vaccines among Obstetrician-Gynaecologists. 妇产科医生对 COVID-19 和 COVID-19 疫苗的认识、态度和做法。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-22 Epub Date: 2023-12-21 DOI: 10.26444/aaem/176959
Nicola Luigi Bragazzi, Michele Buchinger, Lukasz Szarpak, Jaroslaw Chmielewski, Małgorzata Goździewska, Joanna Gotlib, Rola Elias Farah

Introduction and objective: The article assesses the knowledge, attitudes, and practices of Obstetrician-Gynaecologists (OB/GYNs) in Israel regarding COVID-19, its impact on fertility, pregnancy and childbirth, and their positions on COVID-19 vaccines.

Material and methods: A cross-sectional anonymous survey was employed, and the data analyzed using logistic regression models.

Results: A total of 172 OB/GYN participants aged 44.9 years, primarily female (59.7%), mostly attending physicians (60.4%), had a mean knowledge score of 75.62%, with 81.1% having sufficient knowledge about general COVID-19 information, 11.9% having specific knowledge about pregnancy, birth, and breastfeeding, and 40.3% having knowledge about COVID-19 vaccination. Notably, only 27% of participants correctly identified the increased risk of preeclampsia in pregnant women with COVID-19. Nevertheless, all OB/GYN participants recommended the COVID-19 vaccination during pregnancy. The majority (65.1%) recommended vaccination across all trimesters, while a smaller percentage recommended it only in the second (25%) or third (6%) trimesters, and very few in the first trimester (4%). The study found that attitudes towards vaccination were influenced by workplace, role, religion, religious observance, and marital status.

Conclusions: The study showed a good level of knowledge regarding COVID-19 vaccines which contributed to OB/GYNs' recommendations to their patients. These findings can be valuable for designing future COVID-19 vaccination campaigns.

引言和目的:文章评估了以色列妇产科医生(OB/GYN)对 COVID-19、其对生育、怀孕和分娩的影响以及他们对 COVID-19 疫苗的立场的了解、态度和做法:采用横断面匿名调查,并使用逻辑回归模型对数据进行分析:共有 172 名妇产科参与者,年龄为 44.9 岁,主要为女性(59.7%),大部分为主治医师(60.4%),平均知识得分率为 75.62%,其中 81.1%的人对 COVID-19 的一般信息有充分了解,11.9%的人对怀孕、分娩和母乳喂养有具体了解,40.3%的人对 COVID-19 疫苗接种有了解。值得注意的是,只有 27% 的参与者正确识别出接种 COVID-19 的孕妇患先兆子痫的风险会增加。尽管如此,所有妇产科医生都建议孕妇在怀孕期间接种 COVID-19 疫苗。大多数人(65.1%)建议在所有孕期接种疫苗,而较小比例的人只建议在第二孕期(25%)或第三孕期(6%)接种,只有极少数人建议在第一孕期(4%)接种。研究发现,对接种疫苗的态度受工作场所、角色、宗教、宗教信仰和婚姻状况的影响:研究表明,妇产科医生对 COVID-19 疫苗的了解程度较高,这有助于他们向患者提出建议。这些发现对设计未来的 COVID-19 疫苗接种活动很有价值。
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引用次数: 0
Relationship between the components of disability definition and the effectiveness of rehabilitation measures as a process. 残疾定义的组成部分与康复措施作为一个过程的有效性之间的关系。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-22 Epub Date: 2023-12-20 DOI: 10.26444/aaem/177341
Witold Piotr Kołłątaj, Barbara Kołłątaj, Elżbieta Cipora, Katarzyna Sygit, Irena Dorota Karwat

Introduction and objective: The number of disabled persons is most often only estimated. The disabled require multidirectional, effective support in almost every field of functioning. There is no arbitrarily accepted definition of disability, and those currently available outline the ranges of support for which rehabilitation measures are necessary.

Objective: The aim of the review is to present the problem areas that contribute to the definition of disability and their interdependence and effectiveness in relation to rehabilitation interventions, as well as identification of the most frequent medical and social problems interdependent on the quality and feasibility of rehabilitation interventions.

Review methods: Scientific literature in Polish and English for 1993-2023 and legal acts concerning the definition of disability, definition of rehabilitation and the problem of employment were reviewed. The following key words were used to search the NIZP-PZH, MZ, JAHEE and ISAP databases: disabled persons, definitions of disability, rehabilitation as a process, synchronization of thematic groups of disability definitions with the rehabilitation process.

Brief description of the state of knowledge: Disability is a public health problem. The actual determination of the extent, medical and social needs of people with disabilities involves methods and measures for classifying people as disabled. The effects of treatment and rehabilitation are assessed by the level of functioning of the disabled in society.

Summary: The multiplicity of characteristics included in the definitions of disability account for all problems in health and social terms. In view of the social, environmental and cultural changes, the scope of needs of people with disabilities is also changing, which can be seen in newly-developed definitions, including rehabilitation.

导言和目标:残疾人的数量往往只是估计出来的。残疾人几乎在每个功能领域都需要多方位的有效支持。目前还没有一个公认的残疾定义,现有的定义概述了需要康复措施支持的范围:综述的目的是介绍有助于残疾定义的问题领域及其与康复干预措施的相互依存性和有效性,以及确定与康复干预措施的质量和可行性相互依存的最常见的医疗和社会问题:回顾方法:回顾了1993-2023年波兰语和英语的科学文献,以及有关残疾定义、康复定义和就业问题的法案。使用以下关键词在 NIZP-PZH、MZ、JAHEE 和 ISAP 数据库中进行搜索:残疾人、残疾定义、康复作为一个过程、残疾定义专题组与康复过程的同步性:残疾是一个公共卫生问题。在实际确定残疾人的程度、医疗和社会需求时,涉及到将残疾人分类的方法和措施。治疗和康复的效果是通过残疾人在社会中的功能水平来评估的。小结:残疾定义中包含的多种特征说明了健康和社会方面的所有问题。鉴于社会、环境和文化的变化,残疾人的需求范围也在发生变化,这可以从包括康复在内的新定义中看出。
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引用次数: 0
Parasitological contamination of arable soil in selected regions of Poland - preliminary study. 波兰部分地区耕地土壤的寄生虫污染--初步研究。
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-22 Epub Date: 2023-12-21 DOI: 10.26444/aaem/176816
Jolanta Małgorzata Zdybel, Jacek Karamon, Jacek Sroka, Angelina Wójcik-Fatla, Piotr Skowron, Katarzyna Kowalczyk, Jan Jadczyszyn, Tomasz Cencek

Introduction and objective: The hygienic status of arable soils in most developed countries has been unknown. In the presented study, a preliminary investigation was undertaken to determine the contamination with eggs of parasitic nematodes in the soil of arable fields in Poland. The aim of the study was to determine whether such contamination is common enough to constitute a significant problem and what factors may influence it.

Material and methods: The study was conducted in 5 Polish provinces from autumn 2021 to spring 2022. The provinces differed significantly in terms of the area of agricultural land, agricultural suitability, type of soil, scale of cattle and pig breeding, production of manure and slurry, and the use of manures and organic fertilizers for fertilization. A total of 133 soil samples were collected. Parasitological examination of soil samples was carried out using the PN-Z-19006 method [1], with confirmed high sensitivity.

Results: Parasite eggs were found in a total of 67 samples, of which 56 samples contained eggs of roundworms of the genus Ascaris (an average of 3.29 eggs/100 g of soil), 23 contained eggs of whipworms (an average of 1.22 eggs/100 g), and 3 contained eggs of Toxocara (1 egg/100 g).

Conclusions: Differences in the percentage of positive samples were found depending on the period in which the samples were taken. The percentage of positive samples collected in autumn (53.57%) was higher than the percentage of positive samples collected in spring (48.05%). Similarly, the average number of eggs of in positive samples collected in autumn (3.43 eggs/100 g) was higher than the average number of eggs in samples collected in spring (2.90 eggs/100 g). Differences in the percentage of positive samples were also found depending on the region of origin of the samples.

引言和目的:大多数发达国家耕地土壤的卫生状况一直不为人知。本研究对波兰耕地土壤中寄生线虫虫卵的污染情况进行了初步调查。研究的目的是确定这种污染是否普遍到足以构成重大问题,以及哪些因素可能对其产生影响:研究于 2021 年秋季至 2022 年春季在波兰 5 个省进行。这些省份在农业用地面积、农业适宜性、土壤类型、养牛和养猪规模、粪肥和泥浆生产以及使用粪肥和有机肥施肥等方面存在显著差异。共采集了 133 个土壤样本。采用 PN-Z-19006 方法[1]对土壤样本进行了寄生虫学检测,结果表明该方法灵敏度高:结果:共在 67 个样本中发现寄生虫卵,其中 56 个样本含有蛔虫卵(平均每 100 克土壤中有 3.29 个虫卵),23 个样本含有鞭虫卵(平均每 100 克土壤中有 1.22 个虫卵),3 个样本含有弓形虫卵(每 100 克土壤中有 1 个虫卵):不同时期采集的样本阳性率不同。秋季采集的阳性样本比例(53.57%)高于春季采集的阳性样本比例(48.05%)。同样,秋季采集的阳性样本的平均卵数(每 100 克 3.43 个卵)也高于春季采集的样本的平均卵数(每 100 克 2.90 个卵)。根据样本来源地区的不同,阳性样本的百分比也存在差异。
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引用次数: 0
Effects of 2.4 GHz radiofrequency electromagnetic field (RF-EMF) on glioblastoma cells (U -118 MG) 2.4 GHz 射频电磁场(RF-EMF)对胶质母细胞瘤细胞(U -118 MG)的影响
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-21 DOI: 10.26444/aaem/176405
A. Nowak-Terpiłowska, Romuald Górski, Małgorzata Marszałek, S. Wosiński, R. Przesmycki, M. Bugaj, L. Nowosielski, Mikołaj Baranowski, Joanna Zeyland
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引用次数: 0
Surgical resection of lung cancer inhibits mRNA expression of GOT2 gene encoding kynurenine aminotransferase in leukocytes 肺癌手术切除可抑制白细胞中编码犬尿氨酸氨基转移酶的 GOT2 基因的 mRNA 表达
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-21 DOI: 10.26444/aaem/176813
Tomasz Prystupa, Dariusz Sagan, J. Kocki, Tomasz Kocki, Rafał Szymanowski, Jacek Bogucki
Introduction and Objective. Lung cancer is the most common malignant tumour. More than 80% of all diagnosed cases are non-small cell carcinoma which can be effectively treated by radical resection. Despite significant progress in the field of diagnostic and therapeutic methods, the results of lung cancer treatment are still unsatisfactory. Lung cancer is detected relatively late, which leads to an unfavourable prognosis. Kynurenine aminotransferases are an important element of the kynurenine pathway of tryptophan metabolism, which has recently aroused great interest from the aspect of possible use as a target point of personalized therapies in malignant tumours.The aim of the study was to analyze the expression of the selected gene of kynurenine aminotransferases GOT 2 at the mRNA level in peripheral blood leukocytes of patients with lung cancer. Materials and method. The mRNA expression of the GOT 2 gene was tested on blood samples from 50 patients treated surgically for non-small cell lung cancer.The control group consisted of 15 healthy individuals.The determination of mRNA expression of the GOT 2 gene was performed using the real-time PCR method.The GAPDH gene was used as the endogenous reference level. Results. The mRNA expression of the GOT2 gene on the 6th day after surgery was statistically significantly lower than before surgery (p = 0,05). In the study group, the average LogRQ mRNA expression of the GOT2 gene before the procedure was 0.192082±0.292174 in woman. This was statistically significantly higher than in men whose average LogRQ mRNA expression of the GOT2 gene before the procedure was 0.004210±0.235065 (p=0.0183). Conclusions. Surgical resection of lung cancer results in inhibition of GOT2 mRNA expression in leukocytes. Further studies are expected to show whether it may be used as a target point for personalized therapies in lung cancer.
导言和目的。肺癌是最常见的恶性肿瘤。在所有确诊病例中,80% 以上为非小细胞癌,可通过根治性切除术进行有效治疗。尽管在诊断和治疗方法领域取得了重大进展,但肺癌的治疗效果仍不尽如人意。肺癌的发现时间相对较晚,导致预后不良。犬尿氨酸氨基转移酶是色氨酸代谢过程中犬尿氨酸途径的重要组成部分,最近引起了人们的极大兴趣,因为它可能被用作恶性肿瘤个性化疗法的靶点。材料和方法。采用实时 PCR 法检测 GOT 2 基因 mRNA 的表达,以 GAPDH 基因作为内源性参考水平。结果显示术后第 6 天,GOT2 基因的 mRNA 表达量明显低于术前(P = 0.05)。在研究组中,女性术前 GOT2 基因的平均 LogRQ mRNA 表达量为 0.192082±0.292174。这在统计学上明显高于男性,男性术前 GOT2 基因的平均 LogRQ mRNA 表达量为 0.004210±0.235065 (p=0.0183)。结论肺癌手术切除会抑制白细胞中 GOT2 mRNA 的表达。进一步的研究有望显示它是否可作为肺癌个性化疗法的靶点。
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Annals of Agricultural and Environmental Medicine
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