首页 > 最新文献

Annals of Agricultural and Environmental Medicine最新文献

英文 中文
Selected routine laboratory tests in the clinical assessment of patients with obstructive sleep apnea 阻塞性睡眠呼吸暂停患者临床评估中的部分常规实验室检查
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-21 DOI: 10.26444/aaem/177205
Jerzy Mosiewicz, Klaudia Brożyna-Tkaczyk, Elżbieta Reichert, Wojciech Myśliński, L. Panasiuk, Andrzej Jaroszyński, Barbara Mosiewicz-Madejska
{"title":"Selected routine laboratory tests in the clinical assessment of patients with obstructive sleep apnea","authors":"Jerzy Mosiewicz, Klaudia Brożyna-Tkaczyk, Elżbieta Reichert, Wojciech Myśliński, L. Panasiuk, Andrzej Jaroszyński, Barbara Mosiewicz-Madejska","doi":"10.26444/aaem/177205","DOIUrl":"https://doi.org/10.26444/aaem/177205","url":null,"abstract":"","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"65 43","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138950703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rehabilitation after replantation of a non-work-related finger amputation without vascular anastosmosis – case report 无血管吻合的非工作相关手指截肢再植术后的康复--病例报告
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-20 DOI: 10.26444/aaem/176089
Justyna Frasuńska, Dominika Kostka, Beata Tarnacka
Work in agriculture carries the risk of trauma as a result of mechanization (farm equipment and machinery), location of cultivated areas, and multi-functionality. In agriculture, the hands were the most affected parts of the body which sustained injury. Successful suturing of a finger initially disqualified from replantation is rare. The case is presented of a 55-year-old patient who had a non-work-related finger amputation. In a surgical centre not belonging to the reference ones in plastic surgery in Poland, a doctor with six months of surgical experience performed the replantation without vascular reconstruction (the amputated distal part of the finger served as a biological dressing). Despite the lack of vascular reconstruction and unfavourable prognosis, the amputated fragment of the finger maintained a partial blood supply. Subsequent flap surgery in the plastic surgery department, and rehabilitation of the patient due to finger contracture, led to functional recovery of the finger.
由于机械化(农用设备和机械)、耕地位置和多功能性,从事农业工作有遭受创伤的风险。在农业生产中,手是受伤最严重的部位。最初被取消再植资格的手指很少能成功缝合。本病例涉及一名 55 岁的患者,他的手指被非手术截肢。在波兰一家不属于整形外科参考中心的外科中心,一名只有六个月手术经验的医生在没有进行血管重建的情况下进行了再植手术(截取的手指远端部分用作生物敷料)。尽管没有进行血管重建,预后也不乐观,但断指部分仍保持了部分血液供应。随后在整形外科进行了皮瓣手术,患者因手指挛缩进行了康复治疗,手指功能得以恢复。
{"title":"Rehabilitation after replantation of a non-work-related finger amputation without vascular anastosmosis – case report","authors":"Justyna Frasuńska, Dominika Kostka, Beata Tarnacka","doi":"10.26444/aaem/176089","DOIUrl":"https://doi.org/10.26444/aaem/176089","url":null,"abstract":"Work in agriculture carries the risk of trauma as a result of mechanization (farm equipment and machinery), location of cultivated areas, and multi-functionality. In agriculture, the hands were the most affected parts of the body which sustained injury. Successful suturing of a finger initially disqualified from replantation is rare. The case is presented of a 55-year-old patient who had a non-work-related finger amputation. In a surgical centre not belonging to the reference ones in plastic surgery in Poland, a doctor with six months of surgical experience performed the replantation without vascular reconstruction (the amputated distal part of the finger served as a biological dressing). Despite the lack of vascular reconstruction and unfavourable prognosis, the amputated fragment of the finger maintained a partial blood supply. Subsequent flap surgery in the plastic surgery department, and rehabilitation of the patient due to finger contracture, led to functional recovery of the finger.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"51 3","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139169423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidrug resistance of Escherichia coli isolated from the urinary bladder of dogs and cats with suspected urinary tract infections 从疑似尿路感染的狗和猫的膀胱中分离出的大肠埃希菌的多重耐药性
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-20 DOI: 10.26444/aaem/176843
Dawid Jańczak, Piotr Górecki, Rafał Stryjek, Aleksandra Zasada
Introduction and Objective. Escherichia coli is one of the most common bacteria isolated from urine samples collected from dogs and cats with urinary tract infection (UTI). Uncomplicated UTIs in dogs and cats can be treated with short courses of first-line antimicrobial drugs, e.g. amoxicillin, amoxicillin with clavulanic acid, or trimethoprim/sulfonamide. Recurrent or complicated UTIs often require long-term treatment with broad-spectrum antibiotics. However, the choice of drug should be based on antimicrobial susceptibility. Materials and method. Between March – September 2022, E. coli isolates cultured from the urine of 66 dogs and 41 cats with UTI symptoms were tested for antimicrobial resistance by using Minimum Inhibitory Concentration (MIC). Antimicrobial susceptibility was tested for ampicillin, ampicillin/sulbactam, cefazolin, cefuroxime, aztreonam, gentamycin, amikacin, colistin, trimethoprim/sulfamethoxazole, ciprofloxacin, chloramphenicol and tetracycline. Results. The highest prevalence of resistance was documented for ampicillin (68% in dogs, 100% in cats) and ampicillin with sulbactam (59% in dogs, 54% in cats). The most common antimicrobial resistance patterns of E. coli were ampicillin alone (12 isolates, 29.3% in cats) and beta-lactams, including aztreonam (14 isolates, 21.2% in dogs). Conclusions. High resistance to aztreonam (61% and 32% of isolates from dogs and cats, respectively), other beta-lactams, and fluoroquinolones should cause be alarm due to zoonotic potential and cross-transmission of antimicrobial-resistant microorganisms between animals and humans.
引言和目的。大肠杆菌是从患有泌尿道感染(UTI)的猫狗尿液样本中分离出来的最常见细菌之一。犬猫的非复杂性UTI可通过短期一线抗菌药物治疗,如阿莫西林、阿莫西林加克拉维酸或三甲氧苄氨嘧啶/磺胺。复发性或复杂性尿毒症通常需要使用广谱抗生素进行长期治疗。不过,在选择药物时应以抗菌药敏感性为依据。材料与方法。2022 年 3 月至 9 月期间,对从 66 只狗和 41 只猫的尿液中培养出的有 UTI 症状的大肠杆菌分离物进行了最低抑菌浓度(MIC)抗菌药耐药性检测。对氨苄西林、氨苄西林/舒巴坦、头孢唑啉、头孢呋辛、阿曲南、庆大霉素、阿米卡星、可乐定、三甲双氨/磺胺甲噁唑、环丙沙星、氯霉素和四环素进行了抗菌药敏感性检测。结果。氨苄西林的耐药性发生率最高(狗为 68%,猫为 100%),氨苄西林加舒巴坦的耐药性发生率也最高(狗为 59%,猫为 54%)。大肠杆菌最常见的抗菌药耐药性模式是单独使用氨苄西林(12 个分离株,猫为 29.3%)和β-内酰胺类药物,包括阿曲南等(14 个分离株,狗为 21.2%)。结论对阿曲南的高(狗和猫的分离物中分别为 61% 和 32%)耐药性、对其他 beta 内酰胺类药物和氟喹诺酮类药物的高耐药性应引起警惕,因为耐抗菌素微生物有可能在动物和人类之间进行人畜共患病和交叉传播。
{"title":"Multidrug resistance of Escherichia coli isolated from the urinary bladder of dogs and cats with suspected urinary tract infections","authors":"Dawid Jańczak, Piotr Górecki, Rafał Stryjek, Aleksandra Zasada","doi":"10.26444/aaem/176843","DOIUrl":"https://doi.org/10.26444/aaem/176843","url":null,"abstract":"Introduction and Objective. Escherichia coli is one of the most common bacteria isolated from urine samples collected from dogs and cats with urinary tract infection (UTI). Uncomplicated UTIs in dogs and cats can be treated with short courses of first-line antimicrobial drugs, e.g. amoxicillin, amoxicillin with clavulanic acid, or trimethoprim/sulfonamide. Recurrent or complicated UTIs often require long-term treatment with broad-spectrum antibiotics. However, the choice of drug should be based on antimicrobial susceptibility. Materials and method. Between March – September 2022, E. coli isolates cultured from the urine of 66 dogs and 41 cats with UTI symptoms were tested for antimicrobial resistance by using Minimum Inhibitory Concentration (MIC). Antimicrobial susceptibility was tested for ampicillin, ampicillin/sulbactam, cefazolin, cefuroxime, aztreonam, gentamycin, amikacin, colistin, trimethoprim/sulfamethoxazole, ciprofloxacin, chloramphenicol and tetracycline. Results. The highest prevalence of resistance was documented for ampicillin (68% in dogs, 100% in cats) and ampicillin with sulbactam (59% in dogs, 54% in cats). The most common antimicrobial resistance patterns of E. coli were ampicillin alone (12 isolates, 29.3% in cats) and beta-lactams, including aztreonam (14 isolates, 21.2% in dogs). Conclusions. High resistance to aztreonam (61% and 32% of isolates from dogs and cats, respectively), other beta-lactams, and fluoroquinolones should cause be alarm due to zoonotic potential and cross-transmission of antimicrobial-resistant microorganisms between animals and humans.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"23 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138954833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beneficial effects of SARS-CoV-2 vaccination resulting from the COVID-19 pandemic with regard to the uptake of influenza virus, pneumococcal, and herpes zoster adult vaccination – a narrative literature review COVID-19大流行导致的SARS-CoV-2疫苗接种对成人接种流感病毒、肺炎球菌和带状疱疹疫苗的有益影响--叙事性文献综述
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-20 DOI: 10.26444/aaem/176747
Karolina Kłoda, Artur Mierzecki, A. Mastalerz-Migas, M. Babicki
Kłoda
日志
{"title":"Beneficial effects of SARS-CoV-2 vaccination resulting from the COVID-19 pandemic with regard to the uptake of influenza virus, pneumococcal, and herpes zoster adult vaccination – a narrative literature review","authors":"Karolina Kłoda, Artur Mierzecki, A. Mastalerz-Migas, M. Babicki","doi":"10.26444/aaem/176747","DOIUrl":"https://doi.org/10.26444/aaem/176747","url":null,"abstract":"Kłoda","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"117 12","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138958475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of Legionella sp. bacteria in hot water systems in hospitals and nursing homes in the Świętokrzyskie Province of south-eastern Poland 波兰东南部圣十字省(Świętokrzyskie)医院和疗养院热水系统中军团菌的存在情况
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-18 DOI: 10.26444/aaem/176501
Andrzej Szczepanek, P. Tyszko, Paweł Kalinowski, J. Chmielewski, Piotr Choina, G. Nowak-Starz
Introduction and Objective. The occurrence of bacteria of the genus Legionella sp. in hot water supply systems in buildings is a real threat to human health, especially for patients in hospitals and residents of nursing homes. The aim of the study was determination of the degree of colonization of hot water systems in hospitals and nursing homes in the Świętokrzyskie Province in south-east Poland. Materials and method. Between 2014 – 2018, samples were collected from hot water systems in 30 hospitals and 32 nursing homes in order to determine the degree of contamination. 631 samples collected of the bacteria Legionella sp were analyzed. Results . Excessive contamination (≥ 100CFU/100 ml) with the bacteria Legionella sp. was detected in 12.12% (n=71) of samples. Contamination was significantly more frequently detected in samples from hot water systems in nursing homes, compared to hospitals (16.48% vs. 10.37%). Above-standard contamination of hot water systems with Legionella sp. bacteria occurred in 34.43% of the facilities, and was more frequent in hospitals (41.38%) than in the nursing homes (28.13%). In 21.3% of the facilities, contamination was detected many times during the study period. Conclusions. Excessive contamination of hot water systems with Legionella sp. bacteria in the examined facilities was a common phenomenon. The presence of the pathogen in the installations of these facilities may constitute a considerable health hazard for patients and residents.
引言和目的。建筑物热水供应系统中军团菌属细菌的出现是对人类健康的真正威胁,尤其是对医院的病人和疗养院的居民。这项研究的目的是确定波兰东南部圣十字省医院和疗养院热水系统中军团菌的定植程度。材料和方法。2014-2018 年间,从 30 家医院和 32 家疗养院的热水系统中采集了样本,以确定污染程度。对收集到的 631 份样本进行了军团菌分析。结果 .12.12%(n=71)的样本检测到军团菌过度污染(≥ 100CFU/100 ml)。与医院相比,养老院热水系统样本中检出污染的频率明显更高(16.48% 对 10.37%)。34.43% 的机构热水系统受到军团菌污染,医院(41.38%)比疗养院(28.13%)更常见。21.3% 的机构在研究期间多次检测到污染。结论在受检机构中,热水系统被军团菌过度污染是一个普遍现象。这些设施中存在的病原体可能会对病人和居民的健康造成严重危害。
{"title":"Occurrence of Legionella sp. bacteria in hot water systems in hospitals and nursing homes in the Świętokrzyskie Province of south-eastern Poland","authors":"Andrzej Szczepanek, P. Tyszko, Paweł Kalinowski, J. Chmielewski, Piotr Choina, G. Nowak-Starz","doi":"10.26444/aaem/176501","DOIUrl":"https://doi.org/10.26444/aaem/176501","url":null,"abstract":"Introduction and Objective. The occurrence of bacteria of the genus Legionella sp. in hot water supply systems in buildings is a real threat to human health, especially for patients in hospitals and residents of nursing homes. The aim of the study was determination of the degree of colonization of hot water systems in hospitals and nursing homes in the Świętokrzyskie Province in south-east Poland. Materials and method. Between 2014 – 2018, samples were collected from hot water systems in 30 hospitals and 32 nursing homes in order to determine the degree of contamination. 631 samples collected of the bacteria Legionella sp were analyzed. Results . Excessive contamination (≥ 100CFU/100 ml) with the bacteria Legionella sp. was detected in 12.12% (n=71) of samples. Contamination was significantly more frequently detected in samples from hot water systems in nursing homes, compared to hospitals (16.48% vs. 10.37%). Above-standard contamination of hot water systems with Legionella sp. bacteria occurred in 34.43% of the facilities, and was more frequent in hospitals (41.38%) than in the nursing homes (28.13%). In 21.3% of the facilities, contamination was detected many times during the study period. Conclusions. Excessive contamination of hot water systems with Legionella sp. bacteria in the examined facilities was a common phenomenon. The presence of the pathogen in the installations of these facilities may constitute a considerable health hazard for patients and residents.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":" 18","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138963585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of PBDEs in car and airplane dust in Poland – exposure assessment and health risk characterization for selected age ranges 波兰汽车和飞机灰尘中多溴联苯醚的存在情况--选定年龄段的暴露评估和健康风险特征描述
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-15 DOI: 10.26444/aaem/175739
W. Korcz, K. Czaja, Monika Liszewska, Brian Buckley, A. Hernik, Radosław Lewiński, Anna Słomczyńska, P. Struciński
Introduction and Objective . Polybrominated diphenyl ethers (PBDEs) are a class of flame-retarding synthetic compounds. They may cause a potential threat to human health due to their bio-accumulative and toxicological properties, and ubiquitous presence in the environment. Food, and ingested dust constitute principal sources of human exposure to PBDEs. The aim of this study was to assess the potential human exposure to selected polybrominated diphenyl ethers measured in dust found in cars and airplane cabins to characterize the health risk
引言和目的 .多溴联苯醚是一类阻燃合成化合物。由于多溴联苯醚具有生物累积性和毒理学特性,而且在环境中无处不在,因此可能对人类健康造成潜在威胁。食物和摄入的灰尘是人类接触多溴联苯醚的主要来源。这项研究的目的是评估人类接触汽车和飞机机舱灰尘中的特定多溴联苯醚的可能性,以确定其对人体健康的风险。
{"title":"Occurrence of PBDEs in car and airplane dust in Poland – exposure assessment and health risk characterization for selected age ranges","authors":"W. Korcz, K. Czaja, Monika Liszewska, Brian Buckley, A. Hernik, Radosław Lewiński, Anna Słomczyńska, P. Struciński","doi":"10.26444/aaem/175739","DOIUrl":"https://doi.org/10.26444/aaem/175739","url":null,"abstract":"Introduction and Objective . Polybrominated diphenyl ethers (PBDEs) are a class of flame-retarding synthetic compounds. They may cause a potential threat to human health due to their bio-accumulative and toxicological properties, and ubiquitous presence in the environment. Food, and ingested dust constitute principal sources of human exposure to PBDEs. The aim of this study was to assess the potential human exposure to selected polybrominated diphenyl ethers measured in dust found in cars and airplane cabins to characterize the health risk","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"65 8","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular confirmation of the systemic toxoplasmosis in cat 猫全身性弓形虫病的分子确证
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-11 DOI: 10.26444/aaem/176075
J. Sroka, A. Wójcik-Fatla, E. Bilska-Zając, J. Karamon, J. Zdybel, W. Piotrowska, J. Dąbrowska, Małgorzata Samorek-Pieróg, Weronika Korpysa-Dzirba, T. Cencek
Introduction and Objective. Systemic toxoplasmosis with tissue-spread parasites occurring in intermediate hosts may also occur in immunocompromised cats (e.g., infected with FLV or FIV). To the best of our knowledge, no reports have been published on the detection and genotyping of T. gondii DNA in cats with extraintestinal toxoplasmosis in Poland. The article describes the case of the sudden death of 3 out of 4 cats in a cattery, and the detection and molecular characterization of T. gondii DNA detected in the tissues of one of the dead cats
引言和目的。免疫力低下的猫(例如,感染了 FLV 或 FIV)也可能患上中间宿主组织播散寄生虫引起的全身性弓形虫病。据我们所知,波兰还没有关于在患有肠外弓形虫病的猫中检测和分型 T. gondii DNA 的报道。这篇文章描述了一个猫舍中四只猫中有三只突然死亡的病例,以及在其中一只死亡猫的组织中检测到的淋病双球菌 DNA 的检测和分子鉴定结果
{"title":"Molecular confirmation of the systemic toxoplasmosis in cat","authors":"J. Sroka, A. Wójcik-Fatla, E. Bilska-Zając, J. Karamon, J. Zdybel, W. Piotrowska, J. Dąbrowska, Małgorzata Samorek-Pieróg, Weronika Korpysa-Dzirba, T. Cencek","doi":"10.26444/aaem/176075","DOIUrl":"https://doi.org/10.26444/aaem/176075","url":null,"abstract":"Introduction and Objective. Systemic toxoplasmosis with tissue-spread parasites occurring in intermediate hosts may also occur in immunocompromised cats (e.g., infected with FLV or FIV). To the best of our knowledge, no reports have been published on the detection and genotyping of T. gondii DNA in cats with extraintestinal toxoplasmosis in Poland. The article describes the case of the sudden death of 3 out of 4 cats in a cattery, and the detection and molecular characterization of T. gondii DNA detected in the tissues of one of the dead cats","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"76 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138978974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deciphering congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD) associated with constitutional CDK13 pathogenic variants – case report and literature review 解读与CDK13致病基因变异有关的先天性心脏缺陷、面部畸形和智力发育障碍(CHDFIDD)--病例报告和文献综述
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-07 DOI: 10.26444/aaem/175610
Katarzyna Wojciechowska, Michał Kwaśny, Aleksandra Pietrzyk, Monika Lejman
There are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our patient is the first person reported so far with a frameshift mutation which introduce premature stop codon in the first exon of the CDK13 gene. She has symptoms characteristic for congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD).
有21种人类周期蛋白依赖激酶参与细胞周期、转录、RNA剪接、细胞凋亡和神经发生的调控。其中五种:CDK4、CDK5、CDK6、CDK10和CDK13与人类表型相关。迄今为止,只有62例患者出现CDK13基因突变。这些患者发育迟缓,面部畸形,进食困难,不同结构的心脏和大脑缺陷。其中36例存在影响CDK13蛋白激酶结构域的错义突变。我们的患者是迄今为止报道的第一个在CDK13基因的第一个外显子中引入过早停止密码子的移码突变的人。她有先天性心脏缺陷、面部畸形和智力发育障碍(CHDFIDD)的典型症状。
{"title":"Deciphering congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD) associated with constitutional CDK13 pathogenic variants – case report and literature review","authors":"Katarzyna Wojciechowska, Michał Kwaśny, Aleksandra Pietrzyk, Monika Lejman","doi":"10.26444/aaem/175610","DOIUrl":"https://doi.org/10.26444/aaem/175610","url":null,"abstract":"There are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our patient is the first person reported so far with a frameshift mutation which introduce premature stop codon in the first exon of the CDK13 gene. She has symptoms characteristic for congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD).","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"110 10","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138590493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neck pain, disability and mobile phone usage among physiotherapy students – a cross-sectional study 物理治疗专业学生的颈痛、残疾和手机使用情况--一项横断面研究
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-06 DOI: 10.26444/aaem/174679
Agata Czępińśka, Magdalena Zawadka, Piotr Gawda
Introduction and Objective. Modern mobile devices have become tools used for educational, research, business or recreational purposes. Incorrect position during excessive use of a smartphone can lead to biomechanical changes, the most visible of which is the position of the head in protraction, characterized by the protrusion of the head and neck forward in relation to the shoulder girdle and trunk. The aim of the study was to analyze the relationship between disability, neck pain (NP), use of phones before bedtime, and hours of using smartphones. Materials and method. The study involved 146 physiotherapy students aged 18–26. Students were asked to complete pain surveys (VAS pain scale), and Neck Disability Index (NDI). Participants were also asked if their pain lasted longer than 3 months, how long they used their smartphone during the day, and whether they used it before bedtime. Results . Statistically significant differences were found between groups with and without neck pain regarding NDI score (p<0.001). Participants who suffered from neck pain longer than 3 months had greater NDI scores (p=0.03), greater intensity of symptoms (p=0.04), greater problems with reading (p<0.01) and driving (p=0.04) than participants who experienced pain for less than 3 months. Using phones before bedtime was related to problems with focusing (p<0.01). There were statistically significant correlations between the time of phone use and disability in terms of reading (p=0.04), focusing (p<0.001), work (p<0.001) and sleeping (p=0.02). Conclusions . Dysfunctions associated with pain in the cervical section may affect the learning abilities of students and thus the acquisition of professional competencies. Not using a smartphone before bedtime is recommended, as it causes poorer concentration. The longer the time spent using the phone, the more significant the disability.
引言和目的。现代移动设备已经成为用于教育、研究、商业或娱乐目的的工具。过度使用智能手机时不正确的姿势会导致生物力学变化,其中最明显的是头部的位置,其特征是头部和颈部相对于肩带和躯干向前突出。这项研究的目的是分析残疾、颈部疼痛(NP)、睡前使用手机和使用智能手机的时间之间的关系。材料和方法。这项研究涉及146名年龄在18-26岁之间的理疗专业学生。要求学生完成疼痛调查(VAS疼痛量表)和颈部残疾指数(NDI)。参与者还被问及他们的疼痛是否持续超过3个月,他们白天使用智能手机的时间有多长,以及他们是否在睡前使用智能手机。结果。有无颈痛组NDI评分差异有统计学意义(p<0.001)。颈部疼痛超过3个月的参与者NDI评分更高(p=0.03),症状更严重(p=0.04),阅读(p<0.01)和驾驶(p=0.04)的问题也更严重(p=0.04)。睡前使用手机与注意力问题相关(p<0.01)。在阅读(p=0.04)、注意力(p<0.001)、工作(p<0.001)和睡眠(p=0.02)方面,使用手机的时间与残疾之间存在统计学上的显著相关。结论。与颈椎疼痛相关的功能障碍可能影响学生的学习能力,从而影响专业能力的获得。建议睡前不要使用智能手机,因为这会导致注意力不集中。使用手机的时间越长,残疾就越严重。
{"title":"Neck pain, disability and mobile phone usage among physiotherapy students – a cross-sectional study","authors":"Agata Czępińśka, Magdalena Zawadka, Piotr Gawda","doi":"10.26444/aaem/174679","DOIUrl":"https://doi.org/10.26444/aaem/174679","url":null,"abstract":"Introduction and Objective. Modern mobile devices have become tools used for educational, research, business or recreational purposes. Incorrect position during excessive use of a smartphone can lead to biomechanical changes, the most visible of which is the position of the head in protraction, characterized by the protrusion of the head and neck forward in relation to the shoulder girdle and trunk. The aim of the study was to analyze the relationship between disability, neck pain (NP), use of phones before bedtime, and hours of using smartphones. Materials and method. The study involved 146 physiotherapy students aged 18–26. Students were asked to complete pain surveys (VAS pain scale), and Neck Disability Index (NDI). Participants were also asked if their pain lasted longer than 3 months, how long they used their smartphone during the day, and whether they used it before bedtime. Results . Statistically significant differences were found between groups with and without neck pain regarding NDI score (p<0.001). Participants who suffered from neck pain longer than 3 months had greater NDI scores (p=0.03), greater intensity of symptoms (p=0.04), greater problems with reading (p<0.01) and driving (p=0.04) than participants who experienced pain for less than 3 months. Using phones before bedtime was related to problems with focusing (p<0.01). There were statistically significant correlations between the time of phone use and disability in terms of reading (p=0.04), focusing (p<0.001), work (p<0.001) and sleeping (p=0.02). Conclusions . Dysfunctions associated with pain in the cervical section may affect the learning abilities of students and thus the acquisition of professional competencies. Not using a smartphone before bedtime is recommended, as it causes poorer concentration. The longer the time spent using the phone, the more significant the disability.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"40 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138595171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of leaching behaviour of heavy metals from sediments sampled in sewer systems – environmental and public health aspect 下水道系统沉积物重金属浸出行为比较--环境和公共卫生方面
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-01 DOI: 10.26444/aaem/175553
J. Kujawska, Sylwia Duda-Saternus, J. Szulżyk-Cieplak, Jacek Zaburko, Magdalena Piłat-Rożek, K. Jamka, R. Babko, Grzegorz Łagód
Comparison of leaching behaviour of
的浸出行为比较
{"title":"Comparison of leaching behaviour of heavy metals from sediments sampled in sewer systems – environmental and public health aspect","authors":"J. Kujawska, Sylwia Duda-Saternus, J. Szulżyk-Cieplak, Jacek Zaburko, Magdalena Piłat-Rożek, K. Jamka, R. Babko, Grzegorz Łagód","doi":"10.26444/aaem/175553","DOIUrl":"https://doi.org/10.26444/aaem/175553","url":null,"abstract":"Comparison of leaching behaviour of","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":" 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Annals of Agricultural and Environmental Medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1