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2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line 2,4-二硝基苯酚能增强顺铂和依托泊苷对前列腺癌细胞株的细胞毒活性
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-16 DOI: 10.26444/aaem/174919
Grzegorz Adamczuk, E. Humeniuk, Kamila Adamczuk, A. Grabarska, B. Madej-Czerwonka, Mariola Michalczuk, Agnieszka Korga-Plewko, Jarosław Dudka
Introduction. Including additional compounds that disturb the energy metabolism of cancer cells in advanced cancer therapy regimens may be an approach to overcome the problem of drug resistance and the therapeutic effectiveness of classic chemotherapeutics. One of the compounds that decouple oxidative phosphorylation, and thus alter the activity of energy-producing pathways, is 2,4-DNP (2,4-dinitrophenol). Objective. The aim of the study was to assess the ability of the 2,4-DNP to sensitize prostate cancer cells to the action of cisplatin and etoposide, or to intensify their action.
简介在晚期癌症治疗方案中加入更多干扰癌细胞能量代谢的化合物,可能是克服耐药性问题和传统化疗药物疗效的一种方法。2,4-DNP(2,4-二硝基苯酚)是一种能使氧化磷酸化脱钩从而改变能量产生途径活性的化合物。研究目的研究的目的是评估 2,4-DNP 能否使前列腺癌细胞对顺铂和依托泊苷的作用敏感,或加强它们的作用。
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引用次数: 0
Geriatric Depression Scale – 30 assessments: face-to-face or telephone interviews for older people – a randomized crossover study 老年抑郁量表--30 次评估:对老年人进行面对面或电话访谈--随机交叉研究
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-15 DOI: 10.26444/aaem/173530
B. Sozański, A. Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, A. Wilmowska-Pietruszyńska, R. Spalek, A. de Sire
A – Research concept and design, B – Collection and/or assembly of data, C – Data analysis and interpretation, D – Writing the article, E – Critical revision of the article, F –
A - 研究概念和设计,B - 数据收集和/或汇总,C - 数据分析和解释,D - 撰写文章,E - 对文章进行严格修改,F - 对文章进行修改。
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引用次数: 0
Gelatin medium for preserving of Trichinella spp. for quality control in laboratories – estimation of larvae viability 实验室质量控制保存旋毛虫用明胶培养基。幼虫活力的估计
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-14 DOI: 10.26444/aaem/174747
Ewa Bilska-Zając, Mirosław Różycki, Weronika Korpysa-Dzirba, Aneta Bełcik, Jacek Karamon, Jacek Sroka, Małgorzata Samorek-Pieróg, Jolanta Zdybel, Angelina Wójcik-Fatla, Tomasz Cencek
1. Shimoni Z, Froom P. Uncertainties in diagnosis, treatment and prevention of trichinellosis. Exp Rev Anti-infective Therapy. 2015;13(10):1279–1288. CrossRef Google Scholar
1. 周建平,李建平。旋毛虫病诊断、治疗和预防的不确定性。抗感染治疗杂志,2015;13(10):1279-1288。交叉参考谷歌学术
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引用次数: 0
Comparison of the method of quantitative determination of <i>Legionella pneumophila</i> acc. to PN-EN ISO 11731:2017 with the Legiolert™/Quanti-Tray® (IDEXX) &lt;i&gt;嗜肺军团菌定量检测方法的比较acc。符合PN-EN ISO 11731:2017与Legiolert™/Quanti-Tray®(IDEXX)
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-07 DOI: 10.26444/aaem/173402
Renata Matuszewska, Izabela Orych, Marta Bartosik
1. Fields BS, Benson RF, Besser RE. Legionella and legionnaires’ disease: 25 years of investigation. Clin Microbiol Rev. 2002;15(3):506–26. https://doi:10.1128/CMR.15.3.5.... CrossRef Google Scholar
1. 引用本文:Fields BS, Benson RF, Besser RE.军团菌和军团病:25年的调查。临床微生物杂志,2002;15(3):506-26。https://doi: 10.1128 / CMR.15.3.5……交叉参考谷歌学术
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引用次数: 0
Mycobacterium avium and Klebsiella pneumoniae co-infection in the domestic ferret (Mustela putorius furo) – Case Report 家貂(鼬鼬)鸟分枝杆菌和肺炎克雷伯菌合并感染病例报告
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-02 DOI: 10.26444/aaem/174216
Anna Didkowska, Sylwia Brzezińska, Ewa Augustynowicz-Kopeć, Aneta Cieplińska, Ewelina Kwiecień, Blanka Orłowska, Jan Wiśniewski, Magdalena Rzewuska, Krzysztof Anusz
1. Belser JA, Eckert AM, Tumpey TM, et al. Complexities in Ferret Influenza Virus Pathogenesis and Transmission Models. Microbiol Mol Biol Rev. 2016;80(3):733–744. doi:10.1128/MMBR.00022-16. CrossRef Google Scholar
1. Belser JA, Eckert AM, Tumpey TM,等。雪貂流感病毒发病机制和传播模型的复杂性。中国生物医学工程学报,2016;31(3):733-744。doi: 10.1128 / MMBR.00022-16。交叉参考谷歌学术
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引用次数: 0
Copulation of <i>Ixodes ricinus</i> males and females on the host and its potential impact on pathogen transmission 蓖麻伊蚊&lt;/i&gt;雄性和雌性对宿主及其对病原体传播的潜在影响
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-11-02 DOI: 10.26444/aaem/174105
Weronika Buczek, Alicja Buczek, Marek Asman, Katarzyna Bartosik
1. ECDC. European Centre for Disease Prevention and Control and European Food Safety Authority. Ixodes ricinus – current known distribution: May 2020. Stockholm. 2020. https://www.ecdc.europa.eu/en/.... Google Scholar
1. ECDC。欧洲疾病预防和控制中心和欧洲食品安全局。蓖麻伊蚊-目前已知分布:2020年5月。2020年斯德哥尔摩。。https://www.ecdc.europa.eu/en/..。谷歌学者
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引用次数: 0
Body weight and assessment of sexual life – a cross-sectional study 体重与性生活评估——一项横断面研究
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-10-26 DOI: 10.26444/aaem/173221
Maciej Bialorudzki, Joanna Mazur, Józef Haczyński, Alicja Kozakiewicz, Zbigniew Izdebski
Introduction and Objective . Body weight can be one of the health effects affecting people’s well-being in its many aspects. The aim of the study was to assess the relationship between body weight and sexual life. Materials and method . In June 2020 a survey was conducted online on a nationwide representative group of 3,000 Poles. A year later, in June 2021thje survey was repeated on a nationwide representative group of 2,500 Poles. The data obtained from 4,266 respondents were then analyzed. Four proprietary questions were used to assess sexual life, based on which a 3-point scale was developed (2020 – α = 0.80, homogeneity 61%; 2021 – α = 0.77, homogeneity 64%). Results . Excess body weight as measured by BMI was more common in 2021 than in 2020, which confirms the upward trend in body weight in society (55.5% vs. 52.7%). In 2020, more respondents indicated a good assessment of their sexual life than in 2021 (27.3% vs 23.5%, p=0.007). People with excessive body weight rated their sexual life as poorer on the scale (2020 p=0.003; 2021 p=0.009). Multinomial logistic regression showed that people with obesity (BMI>30) had a 1.7 higher increased risk of poor assessment of sexual life than those with normal weight (OR: 1.728; 95% CI: 1.396–2.138; p<0.001). In addition, multinomial logistic regression showed significance for the poor assessment of sexual life for the following factors: age 50–65; female. On the other hand, the following factors were associated with the good assessment of sexual life: age 18–29, being in a relationship, and the year of the study. Conclusions. Body weight may be one of the most important aspects affecting the assessment of a person’s sexual life. Educating patients about the correct body weight is extremely important in order to improve their health and sexual life.
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引用次数: 0
Production of pro-inflammatory mediators stimulated by exposure of poultry house workers to airborne dust particulates 家禽饲养场工人暴露于空气中粉尘颗粒刺激促炎介质的产生
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-10-23 DOI: 10.26444/aaem/174201
Rafał L. Górny, Marcin Cyprowski, Małgorzata Gołofit-Szymczak, Anna Ławniczek-Wałczyk, Agata Stobnicka-Kupiec, Lidia Wolska
1. Owczarek D. Artificial intelligence in poultry industry. What are the latest innovations in poultry farming? Nexocode 2022. https://nexocode.com/blog/post... (access: 2023.06.30). Google Scholar
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引用次数: 0
Opinion of teenagers on smoking-free policy in public places and its determinants – evidence from a global youth tobacco survey in five European countries 青少年对公共场所无烟政策的看法及其决定因素——来自五个欧洲国家的全球青少年烟草调查的证据
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-10-20 DOI: 10.26444/aaem/173531
Beata Świątkowska, Aleksandra Olewnik, Dorota Kaleta
1. Park Lee E, Ren C, Cooper M, et al. Tobacco Product Use Among Middle and High School Students – United States, 2022. Morbidity and Mortality Weekly Report. 2022;71:45. https://www.cdc.gov/mmwr/volum... (access: 2023.08.28). Google Scholar
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引用次数: 0
Comparing results of three measurement techniques used to determine the size of oropharyngeal airway in adults 用于测定成人口咽气道大小的三种测量技术的比较结果
4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-10-18 DOI: 10.26444/aaem/171023
Jakub Bieliński, Filip Jaśkiewicz, Dariusz Timler
1. Hewitt FW. An artificial “air-way” for use during anaesthetisation. The Lancet. 1908;171(4407):490–491. https://doi.org/10.1016/S0140-.... CrossRef Google Scholar
1. 休伊特弗兰克-威廉姆斯。麻醉时使用的人工“气道”。《柳叶刀》,1908;171(4407):490-491。https://doi.org/10.1016/S0140-..。交叉参考谷歌学术
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引用次数: 0
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Annals of Agricultural and Environmental Medicine
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