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Lipoid pneumonia induced by aspiration of liquid paraffin. 液体石蜡吸入致脂质性肺炎
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2023-07-20 DOI: 10.26444/aaem/168783
Konrad Siebert, Ewa Jassem, Maria Porzezińska, Małgorzata Jelitto, Weronika Bernard

Introduction: This case report describes a case of exogenous lipoid pneumonia (ELP) resulting from the inhalation of a lipoid substance. Lipoid pneumonia, also known as cholesterol pneumonia or golden pneumonia, is an uncommon inflammatory lung disease characterized by the presence of lipid-laden macrophages in the alveolar walls and lung interstitial tissue. Exogenous lipoid pneumonia occurs when substances containing lipids enter the airways through aspiration or inhalation, triggering an inflammatory response.

Case report: The patient in this case study was an 83-year-old woman with hypertension and diabetes mellitus who had been using paraffin oil as a mouthwash for an extended period. The diagnosis of exogenous lipoid pneumonia was established based on the patient's history of exposure to liquid paraffin oil, typical radiological findings, and histopathological examination.

介绍。本病例报告描述了一例由吸入类脂物质引起的外源性脂质肺炎(ELP)。脂质肺炎,又称胆固醇肺炎或金色肺炎,是一种罕见的肺部炎症性疾病,其特征是肺泡壁和肺间质组织中存在富含脂质的巨噬细胞。外源性类脂性肺炎发生时,含脂物质通过吸入或吸入进入气道,引发炎症反应。病例报告。本病例研究的患者是一名患有高血压和糖尿病的83岁妇女,她长期使用石蜡油作为漱口水。外源性脂质性肺炎的诊断基于患者接触液体石蜡油的病史、典型的放射学表现和组织病理学检查。
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引用次数: 0
Evidence for external beam radiotherapy in mediastinal Hodgkin and non-Hodgkin lymphoma - systematic review. 外束放疗治疗纵隔霍奇金淋巴瘤和非霍奇金淋巴瘤的证据:系统评价
IF 1.3 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2024-03-25 Epub Date: 2023-06-26 DOI: 10.26444/aaem/168272
Malwina Kowalska, Ewelina Sitarz-Kilian, Klaudia Jaros, Magdalena Koperny, Paweł Moćko, Jacek Siwiec, Paweł Kawalec

Introduction and objective: Proton beam therapy (PBT) provides the opportunity for a more localized delivery of high energy protons and may reduce the damage to healthy tissues and vital organs. The aim of this review was to assess the effects of proton therapy for patients diagnosed with Hodgkin or non-Hodgkin lymphoma treated with mediastinal irradiation.

Review methods: A systematic search of EMBASE, MEDLINE via OVID and Cochrane Library was conducted in May 2022 according to PRISMA guidelines to identify relevant data on the efficacy and toxicity of proton beam therapy for patients diagnosed with Hodgkin or non-Hodgkin lymphoma.

Brief description of the state of knowledge: Of 566 screened abstracts (430 after de-duplication) 11 studies with a total of 529 patients were included. All studies were case series published between 2011-2021. Median range of follow-up time was 15-63.6 months. The overall survival (OS) for 2 years varied from 91% - 98% for 5 of the included studies. Three of the included studies had favourable outcomes with 2-year progression-free survival (PFS) ranging from 73% - 94%. Skin reaction, oesophagitis and fatigue were found to be the most common grade 1 and grade 2 toxicities. No acute or late grade 4 and higher toxicities/adverse events were observed.

Summary: There are data indicating that PBT may to be an effective treatment against mediastinal Hodgkin and non-Hodgkin lymphoma. Because all the studies were case series, the authors of this review have little confidence in the evidence. There remains a need for well-designed randomized controlled trials to inform about the optimal approach to proton irradiation in HL and NHL.

引言和目的。质子束治疗(PBT)为高能质子的局部输送提供了机会,并可能减少对健康组织和重要器官的损害。本综述的目的是评估质子治疗对接受纵隔放射治疗的霍奇金或非霍奇金淋巴瘤患者的效果。复习方法。根据PRISMA指南,于2022年5月通过OVID和Cochrane Library对EMBASE、MEDLINE进行系统检索,以确定质子束治疗对诊断为霍奇金或非霍奇金淋巴瘤患者的疗效和毒性的相关数据。对知识状态的简要描述。在566篇筛选摘要(430篇重复删除后)中,纳入了11项研究,共529例患者。所有研究均为2011-2021年间发表的病例系列。中位随访时间15 ~ 63.6个月。在纳入的5项研究中,2年的总生存率(OS)从91%到98%不等。其中3项研究的2年无进展生存率(PFS)为73% - 94%。皮肤反应、食道炎和疲劳是最常见的1级和2级毒性。未观察到急性或晚期4级及以上的毒性/不良事件。总结。有数据表明PBT可能是治疗纵隔霍奇金淋巴瘤和非霍奇金淋巴瘤的有效方法。由于所有的研究都是病例系列,本综述的作者对证据缺乏信心。仍然需要精心设计的随机对照试验,以了解HL和NHL中质子照射的最佳方法。
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引用次数: 0
Comparative analysis of venous thromboembolic complications in diverse groups of orthopaedic patients. 不同骨科患者静脉血栓栓塞并发症的比较分析
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2023-07-25 DOI: 10.26444/aaem/169698
Mateusz Komisarczuk, Piotr Piech, Grzegorz Staśkiewicz, Robert Węgłowski, Weronika Tuszyńska

Introduction and objective: Venous thromboembolism (VTE) is one of the most important and life-threatening complications in orthopaedic surgery. According to current scientific reports, there are several variables that can affect the severity of CVD, including the site of the pathology or the type of treatment implemented. The aim of the study was to analyze the risk of VTE depending on the location of the pathology, as well as to evaluate the impact of surgical treatment compared to conservative management.

Material and methods: Analysis of laboratory results and clinical picture of 276 patients hospitalized for orthopaedic reasons, admitted between January 2008 - December 2019, with suspected pulmonary embolism (PE).

Results: Among patients diagnosed with PE, the most common location of the disease was in the lower limb 59/116 (50.9%), followed by the pelvis location - 22/116 (19.0%), the spine - 19/116 (16.4%), disseminated lesions in oncological patients - 12/116 (10.3%), and a group of pathologies in the upper limb - 4/116 (3.5%). Significant statistical differences were found between the incidence of PE and the diagnosis of pathology in the lower limb and the pelvis. In the group of patients, there was no statistically significant relationship between the incidence of PE associated with surgical treatment, compared to conservative management.

Conclusions: The group with the highest risk of VTE were lower limb and pelvic pathologies. The results are largely consistent with numerous reports treating the risk of CVD among orthopaedic patient populations.

引言和目标。静脉血栓栓塞症(VTE)是骨科手术中最重要且危及生命的并发症之一。根据目前的科学报告,有几个变量可以影响CVD的严重程度,包括病理部位或实施的治疗类型。本研究的目的是根据病理部位分析VTE的风险,并评估手术治疗与保守治疗相比的影响。材料和方法。对2008年1月至2019年12月期间因骨科原因住院的276名疑似肺栓塞(PE)患者的实验室结果和临床情况进行分析。后果在被诊断为PE的患者中,最常见的病变部位是下肢59/116(50.9%),其次是骨盆部位-22/116(19.0%)、脊椎部位19/116(16.4%)、肿瘤患者的播散性病变12/116(10.3%),上肢的一组病理学–4/116(3.5%)。PE的发生率与下肢和骨盆的病理学诊断之间存在显著的统计学差异。在患者组中,与保守治疗相比,与手术治疗相关的PE发生率之间没有统计学上的显著关系。结论。VTE风险最高的组是下肢和骨盆病变。这一结果与整形外科患者群体中治疗心血管疾病风险的大量报告基本一致。
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引用次数: 0
Occurrence of Dermacentor reticulatus in central-southern Poland, and potential threats to human and animal health. Dermacentor reticulatus 在波兰中南部的出现以及对人类和动物健康的潜在威胁。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2024-01-30 DOI: 10.26444/aaem/178401
Alicja Buczek, Weronika Buczek, Maciej Rudek, Marek Asman, Magdalena Świsłocka, Katarzyna Bartosik

Introduction and objective: Dermacentor reticulatus is one of the tick species of the greatest epidemiological importance in Europe. To date, the Eastern European and Western European populations of this tick species have been separated by an area located in Poland where the species has never been found. In this study, newly discovered D. reticulatus localities in areas transformed by human activities in central-southern Poland are described.

Material and methods: The specimens of the ornate dog tick were identified among ticks collected from companion animals in 2010, 2012, 2013, and 2014. They were examined using PCR methods to detect Borrelia burgdorferi s.l., Rickettsia spp., Anaplasma phagocytophilum, Bartonella spp., Babesia spp., and Toxoplasma gondii. In the case of the positive results, the amplicons were sequenced and examined by a BLAST search.

Results: In total, 6 specimens of D. reticulatus were collected (3 females and 3 males). As declared by the owners, animal hosts stayed in the same area throughout the study period and had never travelled outside their place of residence. As many as 3/6 (50%) of D. reticulatus adults removed from dogs were infected with Rickettsia raoultii.

Conclusions: The results expand the available data on the spread of the ornate dog tick and indicate that, since 2010, this tick species and Rickettsia raoultii transmitted by this tick species have probably been present in this area, which has a strongly transformed agricultural structure and and had previously been regarded as a D. reticulatus-free zone. The presence of the ornate dog tick in urban and suburban habitats in central-southern Poland poses new threats to the health of companion animals and humans associated with the transmission of pathogens by this species.

引言和目的:网斑蜱(Dermacentor reticulatus)是欧洲流行病学上最重要的蜱类之一。迄今为止,这种蜱虫的东欧种群和西欧种群一直被位于波兰的一个从未发现过这种蜱虫的地区分隔开来。本研究描述了在波兰中南部因人类活动而改变的地区新发现的 D. reticulatus:2010 年、2012 年、2013 年和 2014 年从伴侣动物身上采集的蜱虫中鉴定出了华丽狗蜱标本。使用 PCR 方法对这些标本进行了检测,以发现博氏杆菌、立克次体、噬细胞嗜血杆菌、巴顿氏菌、巴贝斯菌和弓形虫。对于阳性结果,对扩增子进行了测序,并通过 BLAST 搜索进行了检验:共采集到 6 个 D. reticulatus 标本(3 个雌性和 3 个雄性)。根据动物主人的申报,动物宿主在整个研究期间都待在同一地区,从未离开过居住地。从狗身上取出的网斑立克次体成虫中有3/6(50%)感染了Rickettsia raoultii:结论:研究结果扩大了有关华丽狗蜱传播的现有数据,并表明自 2010 年以来,该蜱种和由该蜱种传播的 Rickettsia raoultii 很可能已在该地区出现。波兰中南部城市和郊区栖息地出现的华丽狗蜱对伴侣动物和人类的健康构成了新的威胁,这与该物种传播病原体有关。
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引用次数: 0
Prospective assessment of functional and clinical results of surgical patellar stabilization in rural and urban populations. Equal chance to success? 对城乡居民髌骨稳定手术的功能和临床效果进行前瞻性评估。成功机会均等?
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2024-01-29 DOI: 10.26444/aaem/178137
Jacek Walawski, Oliwer Sygacz, Martyna Jarocka, Tomasz Sacewicz

Introduction and objective: Patella dislocation represents 3.3% of all knee injuries often leading to persistent instability. Medial patello-femoral ligament(MPFL) reconstruction is the standard method of treatment in the patellar instability. Rehabilitation after MPFL-R is a long and demanding procedure. The hypothesis presented reflects the idea that despite relatively good access to hospital care and surgical options, the post-operative rehabilitation care system is still inferior in rural areas versus the one offered in major cities and towns.

Material and methods: Between January 2015 - January 2018, 47 patients met the study inclusion criteria, diagnosed and operated on due to patellar instability. 8 patients were lost for full follow-up. Finally, 39 patients were included, divided into two groups - group A (19 from cities), group B (20 from rural area). Prospective KOOS and Kujala scales assessments were conducted: preoperative, 6 and 12 months after surgery. Knee isokinetic muscle strength was measured at 3 stages; prior to surgery, 6 and 12 months after reconstruction.

Results: All patients showed significant improvement measured in the KOOS and Kujala scales after the procedure, compared to the pre-operational results. Despite equal clinical improvement, patients from Group A(city) achieved better functional outcomes as presented in the results of knee extensor functional tests using a Biodex dynamometer.

Conclusions: Rehabilitation after MPFL reconstruction improves muscle strength and clinical outcome. Patients from rural areas had inferior functional results in comparison to the patients from major cities, even 12 months after surgical patella stabilization. Despite the development of roads and transport according to the EU cohesion policy, there are still differences in rehabilitation results between rural and city areas.

引言和目的:髌骨脱位占膝关节损伤总数的 3.3%,通常会导致持续性不稳定。髌骨-股内侧韧带(MPFL)重建是治疗髌骨不稳的标准方法。MPFL-R术后康复是一个漫长而艰巨的过程。本文提出的假设反映了这样一种观点,即尽管医院护理和手术选择相对较好,但农村地区的术后康复护理系统仍不如大城市和城镇:2015 年 1 月至 2018 年 1 月间,47 名患者符合研究纳入标准,因髌骨不稳而被诊断并接受手术。8名患者失去了全面随访的机会。最后,39 名患者被纳入研究,分为两组--A 组(19 名来自城市)和 B 组(20 名来自农村)。分别在术前、术后 6 个月和 12 个月进行了前瞻性 KOOS 和 Kujala 量表评估。在手术前、重建后 6 个月和 12 个月的三个阶段测量了膝关节等速肌力:结果:与术前结果相比,所有患者术后的 KOOS 和 Kujala 量表均有明显改善。尽管临床改善程度相同,但A组(城市)患者在使用Biodex测力计进行的膝关节伸肌功能测试结果中获得了更好的功能结果:结论:MPFL重建术后的康复治疗可改善肌肉力量和临床效果。结论:MPFL 重建后的康复治疗可提高肌肉力量和临床疗效。与来自大城市的患者相比,来自农村地区的患者即使在手术稳定髌骨 12 个月后,其功能效果也不如来自大城市的患者。尽管根据欧盟团结政策发展了道路和交通,但农村和城市地区的康复效果仍存在差异。
{"title":"Prospective assessment of functional and clinical results of surgical patellar stabilization in rural and urban populations. Equal chance to success?","authors":"Jacek Walawski, Oliwer Sygacz, Martyna Jarocka, Tomasz Sacewicz","doi":"10.26444/aaem/178137","DOIUrl":"10.26444/aaem/178137","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Patella dislocation represents 3.3% of all knee injuries often leading to persistent instability. Medial patello-femoral ligament(MPFL) reconstruction is the standard method of treatment in the patellar instability. Rehabilitation after MPFL-R is a long and demanding procedure. The hypothesis presented reflects the idea that despite relatively good access to hospital care and surgical options, the post-operative rehabilitation care system is still inferior in rural areas versus the one offered in major cities and towns.</p><p><strong>Material and methods: </strong>Between January 2015 - January 2018, 47 patients met the study inclusion criteria, diagnosed and operated on due to patellar instability. 8 patients were lost for full follow-up. Finally, 39 patients were included, divided into two groups - group A (19 from cities), group B (20 from rural area). Prospective KOOS and Kujala scales assessments were conducted: preoperative, 6 and 12 months after surgery. Knee isokinetic muscle strength was measured at 3 stages; prior to surgery, 6 and 12 months after reconstruction.</p><p><strong>Results: </strong>All patients showed significant improvement measured in the KOOS and Kujala scales after the procedure, compared to the pre-operational results. Despite equal clinical improvement, patients from Group A(city) achieved better functional outcomes as presented in the results of knee extensor functional tests using a Biodex dynamometer.</p><p><strong>Conclusions: </strong>Rehabilitation after MPFL reconstruction improves muscle strength and clinical outcome. Patients from rural areas had inferior functional results in comparison to the patients from major cities, even 12 months after surgical patella stabilization. Despite the development of roads and transport according to the EU cohesion policy, there are still differences in rehabilitation results between rural and city areas.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Registered incidence of acute upper respiratory tract infections diagnosed by primary care physicians in Poland - 5-year retrospective analysis of the national health insurance database. 波兰初级保健医生诊断的急性上呼吸道感染登记发病率--对国家医疗保险数据库的五年回顾性分析。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2024-03-04 DOI: 10.26444/aaem/183993
Iwona Paciepnik, Agata Bąk, Katarzyna Leoszkiewicz, Adam Windak, Tomasz Madej, Oleszczyk Marek, Krzysztof Studziński, Tomasz Tomasik

Introduction and objective: Upper respiratory tract infection (URTIs), caused by a variety of viruses and sometimes by bacteria, represents the most common acute illness in primary health care. The aim of the study was to explore the registered incidence of URTIs in Poland in the period between 2015-2019, and its burden on the health care system.

Material and methods: A retrospective analysis was carried out of all medical encounters in Poland registered within the national billing database of public healthcare services. Medical services provided due to acute URTIs were classified according to the ICD-10 codes. Registered Incidence Rate (RIR) was calculated yearly, in a 100,000 population. A generalised additive model was used to calculate the Incidence Rate Ratio (IRR).

Results: In the analysed 5-year period, acute URTI was diagnosed in 24.3 million patients (61.7% of the whole population registered in PHC). The RIR of all acute URTIs in PHC was 50,762/100,000/year. Nearly 99% of consultations in this group of patients were provided by PHC physicians. Only 0.8% were referred to an OSC consultation and 0.4% were hospitalised. In PHC, indeterminate URTIs were most frequently diagnosed. The estimated IRR for children aged 1-4 years was 1.65 (95% CI: 1.64; 1.66, p<0.01) and for men 0.79 (95% CI: 0.79; 0.79; p<0.01). In the studied period, the number of patients consulted for acute URTI decreased slightly in PHC, but significantly in specialist services.

Conclusions: The registered incidence of URTIs in Poland burdens mainly PHC physicians. Women and children aged 1-4 years are more frequent users of medical services related to URTIs. It appears that strategies for increasing patient empowerment to provide efficient self-care reducing the utilisation of PHC services are needed.

导言和目的:上呼吸道感染(URTIs)由多种病毒引起,有时也由细菌引起,是初级卫生保健中最常见的急性疾病。本研究旨在探讨 2015-2019 年期间波兰登记的 URTI 发病率及其对医疗保健系统造成的负担:对波兰公共医疗保健服务国家计费数据库中登记的所有医疗事件进行了回顾性分析。因急性尿路感染而提供的医疗服务根据 ICD-10 编码进行分类。每年以 10 万人口为单位计算登记发病率 (RIR)。采用广义相加模型计算发病率比(IRR):在分析的 5 年期间,有 2430 万名患者(占初级保健中心登记人口总数的 61.7%)被诊断为急性尿路感染。在初级保健中心就诊的所有急性尿路感染患者中,发病率为 50,762 例/100,000 人/年。这组患者中近 99% 的咨询由初级保健中心的医生提供。只有0.8%的患者被转诊到门诊部就诊,0.4%的患者住院治疗。在初级保健中心,不确定的尿路感染最常被诊断出来。1-4岁儿童的估计IRR为1.65(95% CI:1.64;1.66,p结论:波兰登记的尿路感染发病率主要给初级保健医生带来了负担。妇女和 1-4 岁儿童更经常使用与尿路感染相关的医疗服务。看来有必要制定战略,增强患者的能力,使其能够提供高效的自我护理,从而减少对初级保健服务的使用。
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引用次数: 0
Analysis of functional efficiency and risk of falls in patients with different types of dementia - preliminary observations. 不同类型痴呆症患者的功能效率和跌倒风险分析--初步观察。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-25 Epub Date: 2023-07-18 DOI: 10.26444/aaem/168787
Magdalena Zawadzka, Joanna Kozłowska, Ewelina Ejchman-Pac, Gabriela Henrykowska, Małgorzata Lewicka

Introduction and objective: Dementia is a multifactorial neurological disease that affects 50 million people worldwide. It is a disorder that impairs cognitive functions, functional efficiency, balance and gait. It contributes to an increased risk of falls, reduces independence in everyday activities and deepens disability. The aim of the study was to investigate the correlation between dementia and independence related to functional efficiency and risk of falls in the elderly.

Material and methods: The eligibility criterion for participation in the study was age over 60, the presence of cognitive disorders, including dementia, and the ability to move with the use of orthopaedic equipment or independently. A total of 51 people participated in the study, including 13 people who underwent rehabilitation procedures. Each subject was evaluated once for cognitive abilities using two types of tests: the ADL scale, MMSE (Mini-Mental state Examination) and three physical fitness tests: SPPB (Short Physical Performance Battery), TUG (Timed Up & Go) and FRT (Functional Reach Test).

Results: The average score of the MMSE test was 13.29±6.23 points, the average of the ADL scale was 4.20±1.23 points. A positive correlation was found between the level of dementia and the independence of the examined person, as well as a positive relationship between the MMSE test and the result of the Functional Reach Test, and the relationship between the ADL scale and the SPPB and 'Get-Up and Go' tests.

Conclusions: It has been demonstrated inter alia that static balance and functional efficiency depends on the patient's independence in everyday activities, and the level of dementia may suggest the patient's dynamic balance. In addition, the need for a broader analysis of targeted studies was recognized to confirm the conclusions obtained.

导言和目的:痴呆症是一种多因素神经系统疾病,影响着全球 5000 万人。它是一种损害认知功能、功能效率、平衡和步态的疾病。它增加了跌倒的风险,降低了日常活动的独立性,并加深了残疾程度。本研究旨在调查老年痴呆症与老年人功能效率和跌倒风险相关的独立性之间的相关性:参与研究的资格标准是年龄超过 60 岁、存在认知障碍(包括痴呆症)以及能够借助矫形设备或独立移动。共有 51 人参与了研究,其中 13 人接受了康复治疗。每位受试者都接受了一次认知能力评估,评估使用两种测试:ADL量表、MMSE(迷你精神状态检查)和三种体能测试:结果:MMSE测试的平均得分为(13.29±6.23)分,ADL量表的平均得分为(4.20±1.23)分。痴呆程度与受检者的独立性之间呈正相关,MMSE 测试与功能性前伸测试结果之间呈正相关,ADL 量表与 SPPB 和 "起立和行走 "测试之间呈正相关:结论:研究表明,静态平衡和功能效率取决于患者在日常活动中的独立性,而痴呆程度可能会影响患者的动态平衡。此外,还认识到有必要对有针对性的研究进行更广泛的分析,以确认所获得的结论。
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引用次数: 0
Relationship between periodontal diseases and non-specific inflammatory bowel diseases – an overview. Part I 牙周病与非特异性炎症性肠病的关系--综述。第一部分
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-21 DOI: 10.26444/aaem/185764
M. Goździewska, Aleksandra Łyszczarz, Monika Kaczoruk, Emilia Kolarzyk
Introduction and Objective. An increasing number of studies indicate that the oral cavity and gastrointestinal tract are interconnected and that there is a potential causal link between non-specific inflammatory bowel diseases (IBD) and oral diseases. Therefore, following the example of the brain-gut axis, the concept of the gum-gut axis has now been put forward. The aim of the review is to assess the literature confirming the existence of the recently proposed gum-gut axis and the resulting relationships between non-specific inflammatory bowel diseases and oral diseases, especially periodontal diseases. Review Methods. The review sums-up information concerning the relationship between periodontal diseases and non-specific bowel diseases. A literature review was carried out by searching databases PubMed, Google Scholar, and Web of Science. Brief description of the state of knowledge. Previously, it was presumed that oral microflora and intestinal microflora remain separate. because it was considered that salivary microbes are killed by stomach and bile acids during translocation through the gastrointestinal tract. Presently, it has been confirmed that oral microorganisms have been found in the faeces of even healthy people. The comparison of oral and intestinal microbiomes of adults does not show full convergence; but pathogenic bacteria such as Klebsiella, Porphyromonas gingivalis and Fusobacterium nucleatum may act as the microbial bridge between periodontitis and IBD. Summary. Dysbiosis of oral microflora may disrupt the normal functioning of the immune system, in this way increasing the development of periodontitis which, in turn, increases the risk of IBD and other complex systemic pathological processes. The gum-gut axis plays a crucial role in these associations. Additional studies are necessary to specify the role of nutritional intervention concerning oral and intestinal microbiome for precise health management.
引言和目的。越来越多的研究表明,口腔和胃肠道是相互关联的,非特异性炎症性肠病(IBD)和口腔疾病之间存在潜在的因果关系。因此,继脑-肠轴之后,现在又提出了牙龈-肠轴的概念。本综述旨在评估证实最近提出的牙龈-肠轴存在的文献,以及非特异性炎症性肠病与口腔疾病(尤其是牙周疾病)之间的关系。综述方法。本综述总结了有关牙周疾病与非特异性肠道疾病之间关系的信息。通过搜索 PubMed、Google Scholar 和 Web of Science 等数据库进行文献综述。知识现状简介。以前,人们认为口腔微生物菌群和肠道微生物菌群是分开的,因为唾液微生物在胃肠道转运过程中会被胃酸和胆汁酸杀死。目前已证实,即使是健康人的粪便中也发现了口腔微生物。成人口腔和肠道微生物组的比较并未显示出完全的趋同性;但克雷伯氏菌、牙龈卟啉单胞菌和核酸镰刀菌等致病菌可能是牙周炎和肠道疾病之间的微生物桥梁。总结。口腔微生物菌群失调可能会破坏免疫系统的正常功能,从而增加牙周炎的发病率,而牙周炎反过来又会增加 IBD 和其他复杂的全身性病理过程的风险。牙龈-肠轴在这些关联中起着至关重要的作用。有必要进行更多的研究,以明确营养干预对口腔和肠道微生物群精确健康管理的作用。
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引用次数: 0
Global warming contributes to reduction in the intensity of Artemisia pollen seasons in Lublin, central-eastern Poland 全球变暖导致波兰中东部卢布林的蒿属植物花粉季节强度降低
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-06 DOI: 10.26444/aaem/184726
Katarzyna Piotrowska-Weryszko, E. Weryszko-Chmielewska, Aneta Sulborska-Różycka, A. Konarska, A. Kubik-Komar
Introduction and Objective. Species of the genus Artemisia (Asteraceae) are weeds and ruderal plants growing in northern temperate regions of the world. Many of them are used in medicine and the cosmetic industry and for culinary purposes. Pollen grains of plants of this genus contain the most important aeroallergens. Materials and Method. An aerobiological study conducted with the volumetric method in Lublin in 2001–2022. Trend lines for the season parameters were established. Spearman’s correlation and stepwise regression analyses were carried out to determine relationships between various parameters of the pollen season and meteorological factors. PCA analysis was also carried out to visually compare the pollen seasons. Results. In Lublin, central-eastern Poland, the Artemisia pollen season lasted on average from the second ten days of July to the end of August, with its beginning depending on the temperature in April and May. The highest pollen concentrations were mainly recorded in the first half of August and were largely dependent on the mean temperature in June and July. The second peak in the pollen season recorded in September was associated with the presence of Artemisia annua pollen. Intense sunshine in June and the higher temperatures in June and July resulted in significant reduction in the Artemisia annual pollen sum (by 65%) over 22 years. Artemisia vulgaris is abundant in the Lublin region and contributes substantially to the amount of Artemisia pollen in the aeroplankton. Conclusions. The downward trend in the amount of Artemisia pollen was a result of the increase in temperatures observed in the summer months, and the declining rainfall rates. The global warming effect is extremely unfavourable for plants of Artemisia vulgaris, as they require moist soil substrates for growth.
引言和目的。蒿属(菊科)物种是生长在世界北温带地区的杂草和灌木植物。其中许多可用于医药、化妆品工业和烹饪。该属植物的花粉粒中含有最重要的过敏原。材料和方法。2001 年至 2022 年在卢布林采用体积测量法进行了空气生物学研究。确定了季节参数的趋势线。进行了斯皮尔曼相关分析和逐步回归分析,以确定花粉季节的各种参数与气象因素之间的关系。还进行了 PCA 分析,以直观地比较花粉季节。研究结果在波兰中东部的卢布林,蒿属植物花粉季节平均从七月的后十天持续到八月底,其开始时间取决于四月和五月的气温。最高的花粉浓度主要出现在八月上半月,主要取决于六月和七月的平均气温。花粉季节的第二个高峰出现在 9 月份,与黄花蒿花粉有关。6 月的强烈日照以及 6 月和 7 月的较高气温导致青蒿年花粉总量在 22 年间显著减少(减少 65%)。卢布林地区盛产黄花蒿,对浮游植物中的黄花蒿花粉量有很大贡献。结论青蒿花粉量的下降趋势是夏季气温升高和降雨率下降的结果。全球变暖效应对蒿属植物极为不利,因为它们需要潮湿的土壤基质才能生长。
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引用次数: 0
Dependence of Lyme disease incidence in children on environmental factors in Wielkopolska Province (West-Central Poland) 大波兰省(波兰中西部)儿童莱姆病发病率与环境因素的关系
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2024-03-01 DOI: 10.26444/aaem/184258
Agnieszka Myszkowska-Torz, Mateusz Tomaszewski, Anna Wierzbicka, G. Rączka, M. Figlerowicz, Katarzyna Mazur-Melewska
Introduction and Objective. Lyme borreliosis (LB) causes hundreds of thousands of new human infections worldwide annually. This is the first study connecting the LB risk to children with environmental factors. Materials and Method. The potential impacts were assessed of environmental factors (deer density in forests, coverage of potential broadleaved forest plant communities, urbanization index) on the number of LB cases in children. Analysis covered the medical records of 196 children diagnosed with LB (ICD-A69.2) from 1 January 2012 – 30 October 2021 in Wielkopolska Province (Poland). Results. All examined factors were positively correlated with LB cases. The highest correlation with the number of patients diagnosed with LB was presented by the degree of urbanization (percentage of the population living in cities in the total inhabitants of the study region). The number of cases was much higher in the second research period (2017–2021). Conclusions. The number of LB cases in children is increasing as the coverage of potential broadleaved forest plant communities increases. The number of cases among males is positively correlated with the coverage. Deer density is positively correlated with the number of LB cases among children – the higher the deer density, the greater the risk of LB infection. LB cases in children are positively correlated with the urbanization index – the more people that live in cities, the greater the risk to children of LB infection.
导言和目的。莱姆包虫病(Lyme borreliosis,LB)每年在全球造成数十万人感染。这是首次将儿童感染莱姆病的风险与环境因素联系起来的研究。材料与方法。评估环境因素(森林中鹿的密度、潜在阔叶林植物群落的覆盖率、城市化指数)对儿童结核病例数的潜在影响。分析涵盖大波兰省(波兰)2012 年 1 月 1 日至 2021 年 10 月 30 日期间确诊为枸杞疹(ICD-A69.2)的 196 名儿童的医疗记录。研究结果所有研究因素均与枸杞病例呈正相关。城市化程度(城市人口占研究地区总人口的百分比)与确诊肺结核患者人数的相关性最高。在第二个研究阶段(2017-2021 年),病例数量要高得多。研究结论随着潜在阔叶林植物群落覆盖率的增加,儿童肺结核病例数也在增加。男性病例数与覆盖率呈正相关。鹿的密度与儿童肺结核病例数呈正相关--鹿的密度越高,感染肺结核的风险就越大。儿童肺结核病例与城市化指数呈正相关--城市人口越多,儿童感染肺结核的风险就越大。
{"title":"Dependence of Lyme disease incidence in children on environmental factors in Wielkopolska Province (West-Central Poland)","authors":"Agnieszka Myszkowska-Torz, Mateusz Tomaszewski, Anna Wierzbicka, G. Rączka, M. Figlerowicz, Katarzyna Mazur-Melewska","doi":"10.26444/aaem/184258","DOIUrl":"https://doi.org/10.26444/aaem/184258","url":null,"abstract":"Introduction and Objective. Lyme borreliosis (LB) causes hundreds of thousands of new human infections worldwide annually. This is the first study connecting the LB risk to children with environmental factors. Materials and Method. The potential impacts were assessed of environmental factors (deer density in forests, coverage of potential broadleaved forest plant communities, urbanization index) on the number of LB cases in children. Analysis covered the medical records of 196 children diagnosed with LB (ICD-A69.2) from 1 January 2012 – 30 October 2021 in Wielkopolska Province (Poland). Results. All examined factors were positively correlated with LB cases. The highest correlation with the number of patients diagnosed with LB was presented by the degree of urbanization (percentage of the population living in cities in the total inhabitants of the study region). The number of cases was much higher in the second research period (2017–2021). Conclusions. The number of LB cases in children is increasing as the coverage of potential broadleaved forest plant communities increases. The number of cases among males is positively correlated with the coverage. Deer density is positively correlated with the number of LB cases among children – the higher the deer density, the greater the risk of LB infection. LB cases in children are positively correlated with the urbanization index – the more people that live in cities, the greater the risk to children of LB infection.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140283114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Annals of Agricultural and Environmental Medicine
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