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Occurrence of Legionella sp. bacteria in hot water systems in hospitals and nursing homes in the Świętokrzyskie Province of south-eastern Poland 波兰东南部圣十字省(Świętokrzyskie)医院和疗养院热水系统中军团菌的存在情况
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-18 DOI: 10.26444/aaem/176501
Andrzej Szczepanek, P. Tyszko, Paweł Kalinowski, J. Chmielewski, Piotr Choina, G. Nowak-Starz
Introduction and Objective. The occurrence of bacteria of the genus Legionella sp. in hot water supply systems in buildings is a real threat to human health, especially for patients in hospitals and residents of nursing homes. The aim of the study was determination of the degree of colonization of hot water systems in hospitals and nursing homes in the Świętokrzyskie Province in south-east Poland. Materials and method. Between 2014 – 2018, samples were collected from hot water systems in 30 hospitals and 32 nursing homes in order to determine the degree of contamination. 631 samples collected of the bacteria Legionella sp were analyzed. Results . Excessive contamination (≥ 100CFU/100 ml) with the bacteria Legionella sp. was detected in 12.12% (n=71) of samples. Contamination was significantly more frequently detected in samples from hot water systems in nursing homes, compared to hospitals (16.48% vs. 10.37%). Above-standard contamination of hot water systems with Legionella sp. bacteria occurred in 34.43% of the facilities, and was more frequent in hospitals (41.38%) than in the nursing homes (28.13%). In 21.3% of the facilities, contamination was detected many times during the study period. Conclusions. Excessive contamination of hot water systems with Legionella sp. bacteria in the examined facilities was a common phenomenon. The presence of the pathogen in the installations of these facilities may constitute a considerable health hazard for patients and residents.
引言和目的。建筑物热水供应系统中军团菌属细菌的出现是对人类健康的真正威胁,尤其是对医院的病人和疗养院的居民。这项研究的目的是确定波兰东南部圣十字省医院和疗养院热水系统中军团菌的定植程度。材料和方法。2014-2018 年间,从 30 家医院和 32 家疗养院的热水系统中采集了样本,以确定污染程度。对收集到的 631 份样本进行了军团菌分析。结果 .12.12%(n=71)的样本检测到军团菌过度污染(≥ 100CFU/100 ml)。与医院相比,养老院热水系统样本中检出污染的频率明显更高(16.48% 对 10.37%)。34.43% 的机构热水系统受到军团菌污染,医院(41.38%)比疗养院(28.13%)更常见。21.3% 的机构在研究期间多次检测到污染。结论在受检机构中,热水系统被军团菌过度污染是一个普遍现象。这些设施中存在的病原体可能会对病人和居民的健康造成严重危害。
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引用次数: 0
Occurrence of PBDEs in car and airplane dust in Poland – exposure assessment and health risk characterization for selected age ranges 波兰汽车和飞机灰尘中多溴联苯醚的存在情况--选定年龄段的暴露评估和健康风险特征描述
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-15 DOI: 10.26444/aaem/175739
W. Korcz, K. Czaja, Monika Liszewska, Brian Buckley, A. Hernik, Radosław Lewiński, Anna Słomczyńska, P. Struciński
Introduction and Objective . Polybrominated diphenyl ethers (PBDEs) are a class of flame-retarding synthetic compounds. They may cause a potential threat to human health due to their bio-accumulative and toxicological properties, and ubiquitous presence in the environment. Food, and ingested dust constitute principal sources of human exposure to PBDEs. The aim of this study was to assess the potential human exposure to selected polybrominated diphenyl ethers measured in dust found in cars and airplane cabins to characterize the health risk
引言和目的 .多溴联苯醚是一类阻燃合成化合物。由于多溴联苯醚具有生物累积性和毒理学特性,而且在环境中无处不在,因此可能对人类健康造成潜在威胁。食物和摄入的灰尘是人类接触多溴联苯醚的主要来源。这项研究的目的是评估人类接触汽车和飞机机舱灰尘中的特定多溴联苯醚的可能性,以确定其对人体健康的风险。
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引用次数: 0
Molecular confirmation of the systemic toxoplasmosis in cat 猫全身性弓形虫病的分子确证
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-11 DOI: 10.26444/aaem/176075
J. Sroka, A. Wójcik-Fatla, E. Bilska-Zając, J. Karamon, J. Zdybel, W. Piotrowska, J. Dąbrowska, Małgorzata Samorek-Pieróg, Weronika Korpysa-Dzirba, T. Cencek
Introduction and Objective. Systemic toxoplasmosis with tissue-spread parasites occurring in intermediate hosts may also occur in immunocompromised cats (e.g., infected with FLV or FIV). To the best of our knowledge, no reports have been published on the detection and genotyping of T. gondii DNA in cats with extraintestinal toxoplasmosis in Poland. The article describes the case of the sudden death of 3 out of 4 cats in a cattery, and the detection and molecular characterization of T. gondii DNA detected in the tissues of one of the dead cats
引言和目的。免疫力低下的猫(例如,感染了 FLV 或 FIV)也可能患上中间宿主组织播散寄生虫引起的全身性弓形虫病。据我们所知,波兰还没有关于在患有肠外弓形虫病的猫中检测和分型 T. gondii DNA 的报道。这篇文章描述了一个猫舍中四只猫中有三只突然死亡的病例,以及在其中一只死亡猫的组织中检测到的淋病双球菌 DNA 的检测和分子鉴定结果
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引用次数: 0
Deciphering congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD) associated with constitutional CDK13 pathogenic variants – case report and literature review 解读与CDK13致病基因变异有关的先天性心脏缺陷、面部畸形和智力发育障碍(CHDFIDD)--病例报告和文献综述
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-07 DOI: 10.26444/aaem/175610
Katarzyna Wojciechowska, Michał Kwaśny, Aleksandra Pietrzyk, Monika Lejman
There are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our patient is the first person reported so far with a frameshift mutation which introduce premature stop codon in the first exon of the CDK13 gene. She has symptoms characteristic for congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD).
有21种人类周期蛋白依赖激酶参与细胞周期、转录、RNA剪接、细胞凋亡和神经发生的调控。其中五种:CDK4、CDK5、CDK6、CDK10和CDK13与人类表型相关。迄今为止,只有62例患者出现CDK13基因突变。这些患者发育迟缓,面部畸形,进食困难,不同结构的心脏和大脑缺陷。其中36例存在影响CDK13蛋白激酶结构域的错义突变。我们的患者是迄今为止报道的第一个在CDK13基因的第一个外显子中引入过早停止密码子的移码突变的人。她有先天性心脏缺陷、面部畸形和智力发育障碍(CHDFIDD)的典型症状。
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引用次数: 0
Neck pain, disability and mobile phone usage among physiotherapy students – a cross-sectional study 物理治疗专业学生的颈痛、残疾和手机使用情况--一项横断面研究
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-06 DOI: 10.26444/aaem/174679
Agata Czępińśka, Magdalena Zawadka, Piotr Gawda
Introduction and Objective. Modern mobile devices have become tools used for educational, research, business or recreational purposes. Incorrect position during excessive use of a smartphone can lead to biomechanical changes, the most visible of which is the position of the head in protraction, characterized by the protrusion of the head and neck forward in relation to the shoulder girdle and trunk. The aim of the study was to analyze the relationship between disability, neck pain (NP), use of phones before bedtime, and hours of using smartphones. Materials and method. The study involved 146 physiotherapy students aged 18–26. Students were asked to complete pain surveys (VAS pain scale), and Neck Disability Index (NDI). Participants were also asked if their pain lasted longer than 3 months, how long they used their smartphone during the day, and whether they used it before bedtime. Results . Statistically significant differences were found between groups with and without neck pain regarding NDI score (p<0.001). Participants who suffered from neck pain longer than 3 months had greater NDI scores (p=0.03), greater intensity of symptoms (p=0.04), greater problems with reading (p<0.01) and driving (p=0.04) than participants who experienced pain for less than 3 months. Using phones before bedtime was related to problems with focusing (p<0.01). There were statistically significant correlations between the time of phone use and disability in terms of reading (p=0.04), focusing (p<0.001), work (p<0.001) and sleeping (p=0.02). Conclusions . Dysfunctions associated with pain in the cervical section may affect the learning abilities of students and thus the acquisition of professional competencies. Not using a smartphone before bedtime is recommended, as it causes poorer concentration. The longer the time spent using the phone, the more significant the disability.
引言和目的。现代移动设备已经成为用于教育、研究、商业或娱乐目的的工具。过度使用智能手机时不正确的姿势会导致生物力学变化,其中最明显的是头部的位置,其特征是头部和颈部相对于肩带和躯干向前突出。这项研究的目的是分析残疾、颈部疼痛(NP)、睡前使用手机和使用智能手机的时间之间的关系。材料和方法。这项研究涉及146名年龄在18-26岁之间的理疗专业学生。要求学生完成疼痛调查(VAS疼痛量表)和颈部残疾指数(NDI)。参与者还被问及他们的疼痛是否持续超过3个月,他们白天使用智能手机的时间有多长,以及他们是否在睡前使用智能手机。结果。有无颈痛组NDI评分差异有统计学意义(p<0.001)。颈部疼痛超过3个月的参与者NDI评分更高(p=0.03),症状更严重(p=0.04),阅读(p<0.01)和驾驶(p=0.04)的问题也更严重(p=0.04)。睡前使用手机与注意力问题相关(p<0.01)。在阅读(p=0.04)、注意力(p<0.001)、工作(p<0.001)和睡眠(p=0.02)方面,使用手机的时间与残疾之间存在统计学上的显著相关。结论。与颈椎疼痛相关的功能障碍可能影响学生的学习能力,从而影响专业能力的获得。建议睡前不要使用智能手机,因为这会导致注意力不集中。使用手机的时间越长,残疾就越严重。
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引用次数: 0
Comparison of leaching behaviour of heavy metals from sediments sampled in sewer systems – environmental and public health aspect 下水道系统沉积物重金属浸出行为比较--环境和公共卫生方面
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-12-01 DOI: 10.26444/aaem/175553
J. Kujawska, Sylwia Duda-Saternus, J. Szulżyk-Cieplak, Jacek Zaburko, Magdalena Piłat-Rożek, K. Jamka, R. Babko, Grzegorz Łagód
Comparison of leaching behaviour of
的浸出行为比较
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引用次数: 0
A case of exudative pleuritis caused by Staphylococcus warneri 一例由沃纳葡萄球菌引起的渗出性胸膜炎病例
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-11-17 DOI: 10.26444/aaem/174906
Mateusz Szymański, M. M. Skiba, Małgorzata Piasecka
This paper discusses the case of a patient with exudative bacterial pneumonia caused by Staphylococcus warneri. The patient had been abusing alcohol and nicotine for several decades, which should be considered an immunosuppressive factor. Staphylococcus warneri is part of the skin microbiome, but can also be a pathogenic agent in certain circumstances. Pleural fluid is an unusual site of isolation for the staphylococcus described. The literature contains case reports of arthritis, endocarditis, urinary tract infection or infection associated with continuous ambulatory peritoneal dialysis caused by Staphylococcus warneri. With the development of medicine, the phenomenon of immunosuppression is becoming more common, posing the threat of an increase in invasive infections caused by coagulase-negative staphylococci. In addition, an overly liberal use of antibiotics may contribute to the generation of multidrug resistance in these micro-organisms.
本文讨论了一名由沃纳葡萄球菌引起的渗出性细菌性肺炎患者的病例。该患者几十年来一直酗酒和滥用尼古丁,这应被视为一种免疫抑制因素。华纳葡萄球菌是皮肤微生物群的一部分,但在某些情况下也可能是致病菌。胸腔积液是所述葡萄球菌的一个不常见的分离部位。文献中包含由沃纳葡萄球菌引起的关节炎、心内膜炎、尿路感染或与连续不卧床腹膜透析相关的感染的病例报告。随着医学的发展,免疫抑制的现象越来越普遍,凝固酶阴性葡萄球菌引起的侵袭性感染有可能增加。此外,过度滥用抗生素可能会导致这些微生物产生多重耐药性。
{"title":"A case of exudative pleuritis caused by Staphylococcus warneri","authors":"Mateusz Szymański, M. M. Skiba, Małgorzata Piasecka","doi":"10.26444/aaem/174906","DOIUrl":"https://doi.org/10.26444/aaem/174906","url":null,"abstract":"This paper discusses the case of a patient with exudative bacterial pneumonia caused by Staphylococcus warneri. The patient had been abusing alcohol and nicotine for several decades, which should be considered an immunosuppressive factor. Staphylococcus warneri is part of the skin microbiome, but can also be a pathogenic agent in certain circumstances. Pleural fluid is an unusual site of isolation for the staphylococcus described. The literature contains case reports of arthritis, endocarditis, urinary tract infection or infection associated with continuous ambulatory peritoneal dialysis caused by Staphylococcus warneri. With the development of medicine, the phenomenon of immunosuppression is becoming more common, posing the threat of an increase in invasive infections caused by coagulase-negative staphylococci. In addition, an overly liberal use of antibiotics may contribute to the generation of multidrug resistance in these micro-organisms.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"18 10","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139265687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line 2,4-二硝基苯酚能增强顺铂和依托泊苷对前列腺癌细胞株的细胞毒活性
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-11-16 DOI: 10.26444/aaem/174919
Grzegorz Adamczuk, E. Humeniuk, Kamila Adamczuk, A. Grabarska, B. Madej-Czerwonka, Mariola Michalczuk, Agnieszka Korga-Plewko, Jarosław Dudka
Introduction. Including additional compounds that disturb the energy metabolism of cancer cells in advanced cancer therapy regimens may be an approach to overcome the problem of drug resistance and the therapeutic effectiveness of classic chemotherapeutics. One of the compounds that decouple oxidative phosphorylation, and thus alter the activity of energy-producing pathways, is 2,4-DNP (2,4-dinitrophenol). Objective. The aim of the study was to assess the ability of the 2,4-DNP to sensitize prostate cancer cells to the action of cisplatin and etoposide, or to intensify their action.
简介在晚期癌症治疗方案中加入更多干扰癌细胞能量代谢的化合物,可能是克服耐药性问题和传统化疗药物疗效的一种方法。2,4-DNP(2,4-二硝基苯酚)是一种能使氧化磷酸化脱钩从而改变能量产生途径活性的化合物。研究目的研究的目的是评估 2,4-DNP 能否使前列腺癌细胞对顺铂和依托泊苷的作用敏感,或加强它们的作用。
{"title":"2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line","authors":"Grzegorz Adamczuk, E. Humeniuk, Kamila Adamczuk, A. Grabarska, B. Madej-Czerwonka, Mariola Michalczuk, Agnieszka Korga-Plewko, Jarosław Dudka","doi":"10.26444/aaem/174919","DOIUrl":"https://doi.org/10.26444/aaem/174919","url":null,"abstract":"Introduction. Including additional compounds that disturb the energy metabolism of cancer cells in advanced cancer therapy regimens may be an approach to overcome the problem of drug resistance and the therapeutic effectiveness of classic chemotherapeutics. One of the compounds that decouple oxidative phosphorylation, and thus alter the activity of energy-producing pathways, is 2,4-DNP (2,4-dinitrophenol). Objective. The aim of the study was to assess the ability of the 2,4-DNP to sensitize prostate cancer cells to the action of cisplatin and etoposide, or to intensify their action.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"24 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139267789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geriatric Depression Scale – 30 assessments: face-to-face or telephone interviews for older people – a randomized crossover study 老年抑郁量表--30 次评估:对老年人进行面对面或电话访谈--随机交叉研究
IF 1.7 4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-11-15 DOI: 10.26444/aaem/173530
B. Sozański, A. Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, A. Wilmowska-Pietruszyńska, R. Spalek, A. de Sire
A – Research concept and design, B – Collection and/or assembly of data, C – Data analysis and interpretation, D – Writing the article, E – Critical revision of the article, F –
A - 研究概念和设计,B - 数据收集和/或汇总,C - 数据分析和解释,D - 撰写文章,E - 对文章进行严格修改,F - 对文章进行修改。
{"title":"Geriatric Depression Scale – 30 assessments: face-to-face or telephone interviews for older people – a randomized crossover study","authors":"B. Sozański, A. Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, A. Wilmowska-Pietruszyńska, R. Spalek, A. de Sire","doi":"10.26444/aaem/173530","DOIUrl":"https://doi.org/10.26444/aaem/173530","url":null,"abstract":"A – Research concept and design, B – Collection and/or assembly of data, C – Data analysis and interpretation, D – Writing the article, E – Critical revision of the article, F –","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"31 8","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139272411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gelatin medium for preserving of Trichinella spp. for quality control in laboratories – estimation of larvae viability 实验室质量控制保存旋毛虫用明胶培养基。幼虫活力的估计
4区 医学 Q4 ENVIRONMENTAL SCIENCES Pub Date : 2023-11-14 DOI: 10.26444/aaem/174747
Ewa Bilska-Zając, Mirosław Różycki, Weronika Korpysa-Dzirba, Aneta Bełcik, Jacek Karamon, Jacek Sroka, Małgorzata Samorek-Pieróg, Jolanta Zdybel, Angelina Wójcik-Fatla, Tomasz Cencek
1. Shimoni Z, Froom P. Uncertainties in diagnosis, treatment and prevention of trichinellosis. Exp Rev Anti-infective Therapy. 2015;13(10):1279–1288. CrossRef Google Scholar
1. 周建平,李建平。旋毛虫病诊断、治疗和预防的不确定性。抗感染治疗杂志,2015;13(10):1279-1288。交叉参考谷歌学术
{"title":"Gelatin medium for preserving of Trichinella spp. for quality control in laboratories – estimation of larvae viability","authors":"Ewa Bilska-Zając, Mirosław Różycki, Weronika Korpysa-Dzirba, Aneta Bełcik, Jacek Karamon, Jacek Sroka, Małgorzata Samorek-Pieróg, Jolanta Zdybel, Angelina Wójcik-Fatla, Tomasz Cencek","doi":"10.26444/aaem/174747","DOIUrl":"https://doi.org/10.26444/aaem/174747","url":null,"abstract":"1. Shimoni Z, Froom P. Uncertainties in diagnosis, treatment and prevention of trichinellosis. Exp Rev Anti-infective Therapy. 2015;13(10):1279–1288. CrossRef Google Scholar","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"33 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134954628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Annals of Agricultural and Environmental Medicine
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