Andrzej Szczepanek, P. Tyszko, Paweł Kalinowski, J. Chmielewski, Piotr Choina, G. Nowak-Starz
Introduction and Objective. The occurrence of bacteria of the genus Legionella sp. in hot water supply systems in buildings is a real threat to human health, especially for patients in hospitals and residents of nursing homes. The aim of the study was determination of the degree of colonization of hot water systems in hospitals and nursing homes in the Świętokrzyskie Province in south-east Poland. Materials and method. Between 2014 – 2018, samples were collected from hot water systems in 30 hospitals and 32 nursing homes in order to determine the degree of contamination. 631 samples collected of the bacteria Legionella sp were analyzed. Results . Excessive contamination (≥ 100CFU/100 ml) with the bacteria Legionella sp. was detected in 12.12% (n=71) of samples. Contamination was significantly more frequently detected in samples from hot water systems in nursing homes, compared to hospitals (16.48% vs. 10.37%). Above-standard contamination of hot water systems with Legionella sp. bacteria occurred in 34.43% of the facilities, and was more frequent in hospitals (41.38%) than in the nursing homes (28.13%). In 21.3% of the facilities, contamination was detected many times during the study period. Conclusions. Excessive contamination of hot water systems with Legionella sp. bacteria in the examined facilities was a common phenomenon. The presence of the pathogen in the installations of these facilities may constitute a considerable health hazard for patients and residents.
{"title":"Occurrence of Legionella sp. bacteria in hot water systems in hospitals and nursing homes in the Świętokrzyskie Province of south-eastern Poland","authors":"Andrzej Szczepanek, P. Tyszko, Paweł Kalinowski, J. Chmielewski, Piotr Choina, G. Nowak-Starz","doi":"10.26444/aaem/176501","DOIUrl":"https://doi.org/10.26444/aaem/176501","url":null,"abstract":"Introduction and Objective. The occurrence of bacteria of the genus Legionella sp. in hot water supply systems in buildings is a real threat to human health, especially for patients in hospitals and residents of nursing homes. The aim of the study was determination of the degree of colonization of hot water systems in hospitals and nursing homes in the Świętokrzyskie Province in south-east Poland. Materials and method. Between 2014 – 2018, samples were collected from hot water systems in 30 hospitals and 32 nursing homes in order to determine the degree of contamination. 631 samples collected of the bacteria Legionella sp were analyzed. Results . Excessive contamination (≥ 100CFU/100 ml) with the bacteria Legionella sp. was detected in 12.12% (n=71) of samples. Contamination was significantly more frequently detected in samples from hot water systems in nursing homes, compared to hospitals (16.48% vs. 10.37%). Above-standard contamination of hot water systems with Legionella sp. bacteria occurred in 34.43% of the facilities, and was more frequent in hospitals (41.38%) than in the nursing homes (28.13%). In 21.3% of the facilities, contamination was detected many times during the study period. Conclusions. Excessive contamination of hot water systems with Legionella sp. bacteria in the examined facilities was a common phenomenon. The presence of the pathogen in the installations of these facilities may constitute a considerable health hazard for patients and residents.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":" 18","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138963585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Korcz, K. Czaja, Monika Liszewska, Brian Buckley, A. Hernik, Radosław Lewiński, Anna Słomczyńska, P. Struciński
Introduction and Objective . Polybrominated diphenyl ethers (PBDEs) are a class of flame-retarding synthetic compounds. They may cause a potential threat to human health due to their bio-accumulative and toxicological properties, and ubiquitous presence in the environment. Food, and ingested dust constitute principal sources of human exposure to PBDEs. The aim of this study was to assess the potential human exposure to selected polybrominated diphenyl ethers measured in dust found in cars and airplane cabins to characterize the health risk
{"title":"Occurrence of PBDEs in car and airplane dust in Poland – exposure assessment and health risk characterization for selected age ranges","authors":"W. Korcz, K. Czaja, Monika Liszewska, Brian Buckley, A. Hernik, Radosław Lewiński, Anna Słomczyńska, P. Struciński","doi":"10.26444/aaem/175739","DOIUrl":"https://doi.org/10.26444/aaem/175739","url":null,"abstract":"Introduction and Objective . Polybrominated diphenyl ethers (PBDEs) are a class of flame-retarding synthetic compounds. They may cause a potential threat to human health due to their bio-accumulative and toxicological properties, and ubiquitous presence in the environment. Food, and ingested dust constitute principal sources of human exposure to PBDEs. The aim of this study was to assess the potential human exposure to selected polybrominated diphenyl ethers measured in dust found in cars and airplane cabins to characterize the health risk","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"65 8","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138999021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Sroka, A. Wójcik-Fatla, E. Bilska-Zając, J. Karamon, J. Zdybel, W. Piotrowska, J. Dąbrowska, Małgorzata Samorek-Pieróg, Weronika Korpysa-Dzirba, T. Cencek
Introduction and Objective. Systemic toxoplasmosis with tissue-spread parasites occurring in intermediate hosts may also occur in immunocompromised cats (e.g., infected with FLV or FIV). To the best of our knowledge, no reports have been published on the detection and genotyping of T. gondii DNA in cats with extraintestinal toxoplasmosis in Poland. The article describes the case of the sudden death of 3 out of 4 cats in a cattery, and the detection and molecular characterization of T. gondii DNA detected in the tissues of one of the dead cats
引言和目的。免疫力低下的猫(例如,感染了 FLV 或 FIV)也可能患上中间宿主组织播散寄生虫引起的全身性弓形虫病。据我们所知,波兰还没有关于在患有肠外弓形虫病的猫中检测和分型 T. gondii DNA 的报道。这篇文章描述了一个猫舍中四只猫中有三只突然死亡的病例,以及在其中一只死亡猫的组织中检测到的淋病双球菌 DNA 的检测和分子鉴定结果
{"title":"Molecular confirmation of the systemic toxoplasmosis in cat","authors":"J. Sroka, A. Wójcik-Fatla, E. Bilska-Zając, J. Karamon, J. Zdybel, W. Piotrowska, J. Dąbrowska, Małgorzata Samorek-Pieróg, Weronika Korpysa-Dzirba, T. Cencek","doi":"10.26444/aaem/176075","DOIUrl":"https://doi.org/10.26444/aaem/176075","url":null,"abstract":"Introduction and Objective. Systemic toxoplasmosis with tissue-spread parasites occurring in intermediate hosts may also occur in immunocompromised cats (e.g., infected with FLV or FIV). To the best of our knowledge, no reports have been published on the detection and genotyping of T. gondii DNA in cats with extraintestinal toxoplasmosis in Poland. The article describes the case of the sudden death of 3 out of 4 cats in a cattery, and the detection and molecular characterization of T. gondii DNA detected in the tissues of one of the dead cats","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"76 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138978974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarzyna Wojciechowska, Michał Kwaśny, Aleksandra Pietrzyk, Monika Lejman
There are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our patient is the first person reported so far with a frameshift mutation which introduce premature stop codon in the first exon of the CDK13 gene. She has symptoms characteristic for congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD).
{"title":"Deciphering congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD) associated with constitutional CDK13 pathogenic variants – case report and literature review","authors":"Katarzyna Wojciechowska, Michał Kwaśny, Aleksandra Pietrzyk, Monika Lejman","doi":"10.26444/aaem/175610","DOIUrl":"https://doi.org/10.26444/aaem/175610","url":null,"abstract":"There are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our patient is the first person reported so far with a frameshift mutation which introduce premature stop codon in the first exon of the CDK13 gene. She has symptoms characteristic for congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD).","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"110 10","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138590493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction and Objective. Modern mobile devices have become tools used for educational, research, business or recreational purposes. Incorrect position during excessive use of a smartphone can lead to biomechanical changes, the most visible of which is the position of the head in protraction, characterized by the protrusion of the head and neck forward in relation to the shoulder girdle and trunk. The aim of the study was to analyze the relationship between disability, neck pain (NP), use of phones before bedtime, and hours of using smartphones. Materials and method. The study involved 146 physiotherapy students aged 18–26. Students were asked to complete pain surveys (VAS pain scale), and Neck Disability Index (NDI). Participants were also asked if their pain lasted longer than 3 months, how long they used their smartphone during the day, and whether they used it before bedtime. Results . Statistically significant differences were found between groups with and without neck pain regarding NDI score (p<0.001). Participants who suffered from neck pain longer than 3 months had greater NDI scores (p=0.03), greater intensity of symptoms (p=0.04), greater problems with reading (p<0.01) and driving (p=0.04) than participants who experienced pain for less than 3 months. Using phones before bedtime was related to problems with focusing (p<0.01). There were statistically significant correlations between the time of phone use and disability in terms of reading (p=0.04), focusing (p<0.001), work (p<0.001) and sleeping (p=0.02). Conclusions . Dysfunctions associated with pain in the cervical section may affect the learning abilities of students and thus the acquisition of professional competencies. Not using a smartphone before bedtime is recommended, as it causes poorer concentration. The longer the time spent using the phone, the more significant the disability.
{"title":"Neck pain, disability and mobile phone usage among physiotherapy students – a cross-sectional study","authors":"Agata Czępińśka, Magdalena Zawadka, Piotr Gawda","doi":"10.26444/aaem/174679","DOIUrl":"https://doi.org/10.26444/aaem/174679","url":null,"abstract":"Introduction and Objective. Modern mobile devices have become tools used for educational, research, business or recreational purposes. Incorrect position during excessive use of a smartphone can lead to biomechanical changes, the most visible of which is the position of the head in protraction, characterized by the protrusion of the head and neck forward in relation to the shoulder girdle and trunk. The aim of the study was to analyze the relationship between disability, neck pain (NP), use of phones before bedtime, and hours of using smartphones. Materials and method. The study involved 146 physiotherapy students aged 18–26. Students were asked to complete pain surveys (VAS pain scale), and Neck Disability Index (NDI). Participants were also asked if their pain lasted longer than 3 months, how long they used their smartphone during the day, and whether they used it before bedtime. Results . Statistically significant differences were found between groups with and without neck pain regarding NDI score (p<0.001). Participants who suffered from neck pain longer than 3 months had greater NDI scores (p=0.03), greater intensity of symptoms (p=0.04), greater problems with reading (p<0.01) and driving (p=0.04) than participants who experienced pain for less than 3 months. Using phones before bedtime was related to problems with focusing (p<0.01). There were statistically significant correlations between the time of phone use and disability in terms of reading (p=0.04), focusing (p<0.001), work (p<0.001) and sleeping (p=0.02). Conclusions . Dysfunctions associated with pain in the cervical section may affect the learning abilities of students and thus the acquisition of professional competencies. Not using a smartphone before bedtime is recommended, as it causes poorer concentration. The longer the time spent using the phone, the more significant the disability.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"40 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138595171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Kujawska, Sylwia Duda-Saternus, J. Szulżyk-Cieplak, Jacek Zaburko, Magdalena Piłat-Rożek, K. Jamka, R. Babko, Grzegorz Łagód
Comparison of leaching behaviour of
的浸出行为比较
{"title":"Comparison of leaching behaviour of heavy metals from sediments sampled in sewer systems – environmental and public health aspect","authors":"J. Kujawska, Sylwia Duda-Saternus, J. Szulżyk-Cieplak, Jacek Zaburko, Magdalena Piłat-Rożek, K. Jamka, R. Babko, Grzegorz Łagód","doi":"10.26444/aaem/175553","DOIUrl":"https://doi.org/10.26444/aaem/175553","url":null,"abstract":"Comparison of leaching behaviour of","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":" 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138620720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateusz Szymański, M. M. Skiba, Małgorzata Piasecka
This paper discusses the case of a patient with exudative bacterial pneumonia caused by Staphylococcus warneri. The patient had been abusing alcohol and nicotine for several decades, which should be considered an immunosuppressive factor. Staphylococcus warneri is part of the skin microbiome, but can also be a pathogenic agent in certain circumstances. Pleural fluid is an unusual site of isolation for the staphylococcus described. The literature contains case reports of arthritis, endocarditis, urinary tract infection or infection associated with continuous ambulatory peritoneal dialysis caused by Staphylococcus warneri. With the development of medicine, the phenomenon of immunosuppression is becoming more common, posing the threat of an increase in invasive infections caused by coagulase-negative staphylococci. In addition, an overly liberal use of antibiotics may contribute to the generation of multidrug resistance in these micro-organisms.
{"title":"A case of exudative pleuritis caused by Staphylococcus warneri","authors":"Mateusz Szymański, M. M. Skiba, Małgorzata Piasecka","doi":"10.26444/aaem/174906","DOIUrl":"https://doi.org/10.26444/aaem/174906","url":null,"abstract":"This paper discusses the case of a patient with exudative bacterial pneumonia caused by Staphylococcus warneri. The patient had been abusing alcohol and nicotine for several decades, which should be considered an immunosuppressive factor. Staphylococcus warneri is part of the skin microbiome, but can also be a pathogenic agent in certain circumstances. Pleural fluid is an unusual site of isolation for the staphylococcus described. The literature contains case reports of arthritis, endocarditis, urinary tract infection or infection associated with continuous ambulatory peritoneal dialysis caused by Staphylococcus warneri. With the development of medicine, the phenomenon of immunosuppression is becoming more common, posing the threat of an increase in invasive infections caused by coagulase-negative staphylococci. In addition, an overly liberal use of antibiotics may contribute to the generation of multidrug resistance in these micro-organisms.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"18 10","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139265687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grzegorz Adamczuk, E. Humeniuk, Kamila Adamczuk, A. Grabarska, B. Madej-Czerwonka, Mariola Michalczuk, Agnieszka Korga-Plewko, Jarosław Dudka
Introduction. Including additional compounds that disturb the energy metabolism of cancer cells in advanced cancer therapy regimens may be an approach to overcome the problem of drug resistance and the therapeutic effectiveness of classic chemotherapeutics. One of the compounds that decouple oxidative phosphorylation, and thus alter the activity of energy-producing pathways, is 2,4-DNP (2,4-dinitrophenol). Objective. The aim of the study was to assess the ability of the 2,4-DNP to sensitize prostate cancer cells to the action of cisplatin and etoposide, or to intensify their action.
{"title":"2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line","authors":"Grzegorz Adamczuk, E. Humeniuk, Kamila Adamczuk, A. Grabarska, B. Madej-Czerwonka, Mariola Michalczuk, Agnieszka Korga-Plewko, Jarosław Dudka","doi":"10.26444/aaem/174919","DOIUrl":"https://doi.org/10.26444/aaem/174919","url":null,"abstract":"Introduction. Including additional compounds that disturb the energy metabolism of cancer cells in advanced cancer therapy regimens may be an approach to overcome the problem of drug resistance and the therapeutic effectiveness of classic chemotherapeutics. One of the compounds that decouple oxidative phosphorylation, and thus alter the activity of energy-producing pathways, is 2,4-DNP (2,4-dinitrophenol). Objective. The aim of the study was to assess the ability of the 2,4-DNP to sensitize prostate cancer cells to the action of cisplatin and etoposide, or to intensify their action.","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"24 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139267789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Sozański, A. Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, A. Wilmowska-Pietruszyńska, R. Spalek, A. de Sire
A – Research concept and design, B – Collection and/or assembly of data, C – Data analysis and interpretation, D – Writing the article, E – Critical revision of the article, F –
{"title":"Geriatric Depression Scale – 30 assessments: face-to-face or telephone interviews for older people – a randomized crossover study","authors":"B. Sozański, A. Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, A. Wilmowska-Pietruszyńska, R. Spalek, A. de Sire","doi":"10.26444/aaem/173530","DOIUrl":"https://doi.org/10.26444/aaem/173530","url":null,"abstract":"A – Research concept and design, B – Collection and/or assembly of data, C – Data analysis and interpretation, D – Writing the article, E – Critical revision of the article, F –","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"31 8","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139272411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ewa Bilska-Zając, Mirosław Różycki, Weronika Korpysa-Dzirba, Aneta Bełcik, Jacek Karamon, Jacek Sroka, Małgorzata Samorek-Pieróg, Jolanta Zdybel, Angelina Wójcik-Fatla, Tomasz Cencek
1. Shimoni Z, Froom P. Uncertainties in diagnosis, treatment and prevention of trichinellosis. Exp Rev Anti-infective Therapy. 2015;13(10):1279–1288. CrossRef Google Scholar
{"title":"Gelatin medium for preserving of Trichinella spp. for quality control in laboratories – estimation of larvae viability","authors":"Ewa Bilska-Zając, Mirosław Różycki, Weronika Korpysa-Dzirba, Aneta Bełcik, Jacek Karamon, Jacek Sroka, Małgorzata Samorek-Pieróg, Jolanta Zdybel, Angelina Wójcik-Fatla, Tomasz Cencek","doi":"10.26444/aaem/174747","DOIUrl":"https://doi.org/10.26444/aaem/174747","url":null,"abstract":"1. Shimoni Z, Froom P. Uncertainties in diagnosis, treatment and prevention of trichinellosis. Exp Rev Anti-infective Therapy. 2015;13(10):1279–1288. CrossRef Google Scholar","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":"33 20","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134954628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}