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Trends in physical activity in adolescents participating and not participating in organized team or individual physical activity. 参加和不参加有组织的团队或个人体育活动的青少年的体育活动趋势。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-04-03 DOI: 10.26444/aaem/162040
Dorota Groffik, Karel Fromel, Mateusz Ziemba, Josef Mitas

Introduction and objective: Participation of adolescents in organized physical activity (PA), together with physical education, is essential for the development of a habit of regular PA, achievement of PA recommendations and adoption of physical literacy. The aim of the study is to identify the trends and differences in PA levels between adolescents participating in organized team PA, organized individual PA, and those not participating in organized PA. Another aim is to formulate proposals to eliminate the negative effects of the pandemic on adolescents' participation in organized PA.

Material and methods: The research took place between 2012-2021 in 51 secondary schools and involved a total of 1,202 boys and 1,561 girls. Participation in organized PA was examined using the 'Sports preferences survey'. Weekly PA was investigated by means of the 'International Physical Activity Questionnaire-Long Form'.

Results: The results confirmed the negative trend in participation in organized PA. However, this was predominantly caused by the negative effects of the pandemic in 2020-2021. Boys participating in organized team and individual PA had more school PA, recreation PA, vigorous PA, moderate PA and overall PA during the week, compared with boys not participating in organized PA (girls had more vigorous PA, moderate PA and overall PA).

Conclusions: Participation in organized team PA and individual PA plays an important role, primarily in supporting vigorous PA but also in overall weekly PA among boys and girls. The negative effects of the pandemic should be eliminated by increasing adolescents' participation in various forms of organized PA with an emphasis on organized individual PA which can be regularly pursued, even under restrictive measures at home, in the countryside or in nature.

简介和目标:青少年参与有组织的体育活动以及体育教育,对于养成定期体育活动的习惯、实现体育活动建议和普及体育知识至关重要。本研究的目的是确定参加有组织的团队PA、有组织的个人PA和未参加有组织PA的青少年之间PA水平的趋势和差异。另一个目的是制定建议,消除疫情对青少年参与有组织的PA的负面影响。材料和方法:这项研究于2012-2021年间在51所中学进行,共有1202名男孩和1561名女孩参与。使用“体育偏好调查”对参与有组织的PA进行了调查。通过“国际体育活动问卷长表”对每周PA进行调查。结果:结果证实了参与有组织PA的负面趋势。然而,这主要是由2020-2021年疫情的负面影响造成的。与未参加有组织PA的男孩相比,参加有组织团队和个人PA的男孩在一周内有更多的学校PA、娱乐PA、剧烈PA、中度PA和总体PA(女孩有更多的剧烈PA、中等PA和整体PA)。结论:参与有组织团队PA和个人PA起着重要作用,主要是支持强有力的PA,但也支持男孩和女孩每周的PA。应通过增加青少年参与各种形式的有组织的PA来消除疫情的负面影响,重点是有组织的个人PA,即使在家里、农村或大自然中采取限制措施,也可以定期进行。
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引用次数: 1
Improving community-based COPD care in general practice in Poland - a cluster randomized controlled trial. 波兰全科医学中改善社区COPD护理——一项集群随机对照试验。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-05-11 DOI: 10.26444/aaem/163200
Anna Kowalczyk, Izabela Zakowska, Ewa Andrzejewska, Jacek Grabowski, Maciek Godycki-Cwirko, Katarzyna Kosiek

Introduction and objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. The aim of the study was to evaluate the impact of intervention on exacerbations of COPD in elderly patients compared to those receiving usual care.

Material and methods: A 12 month, multicentre, three-arm, pragmatic, cluster randomized controlled trial was performed (CRCT). The 97 largest PHC clinics with at least 46 COPD registered patients in the Łódż Province, in central Poland. In total, 27,534 COPD patients aged 65 and over were identified from the National Health Fund (NFZ) electronic health records. A checklist of selected, recommended COPD interventions sent to GPs once or twice by post and shown on their desk in their clinics, in the intervention arms.

Results: A primary outcome was the difference in exacerbations or deaths between the 3 arms at 12 months. The amounts of specific short- and long-acting drugs purchased by patients were also assessed as secondary outcomes. Only 0.44% (122 of 27 534) COPD patients demonstrated exacerbations after the one-year study period. No statistically significant associations were found between interventions and exacerbations (p=0.1568, Chi-Square) or deaths (p=0.8128, Chi-Square) at 12 months.

Conclusions: As this study coincided with the pandemic period, the results should be interpreted with care. The intervention had no association with exacerbations. Future research on interventions aimed at improving chronic illness care are needed.

引言和目的:慢性阻塞性肺病(COPD)是全球第三大死亡原因。该研究的目的是评估与接受常规护理的老年患者相比,干预对COPD恶化的影响。材料和方法:进行了一项为期12个月的多中心、三组、实用性、整群随机对照试验(CRCT)。波兰中部的Łódż省有97家最大的初级保健诊所,至少有46名COPD患者登记在册。从国家卫生基金(NFZ)的电子健康记录中,总共确认了27534名65岁及以上的COPD患者。一份选定的、推荐的COPD干预措施清单通过邮寄一到两次发送给全科医生,并显示在他们诊所的桌子上。结果:主要结果是3组患者在12个月时病情恶化或死亡的差异。患者购买的特定短期和长期药物的数量也被评估为次要结果。在一年的研究期后,只有0.44%(27534名患者中的122名)的COPD患者表现出病情恶化。干预措施与12个月时的病情恶化(p=0.1568,卡方)或死亡(p=0.8128,卡方)之间没有发现统计学上显著的相关性。结论:由于这项研究恰逢疫情期间,应谨慎解读结果。干预措施与病情恶化无关。未来需要对旨在改善慢性病护理的干预措施进行研究。
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引用次数: 0
Comparison of the effectiveness of various parasitological methods in detecting nematode eggs in different types of soil. 不同寄生虫学方法在不同类型土壤中检测线虫卵的有效性比较。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-09-27 DOI: 10.26444/aaem/172454
Jolanta Małgorzata Zdybel, Jacek Sroka, Jacek Karamon, Ewa Bilska-Zając, Angelina Wójcik-Fatla, Teresa Kłapeć, Piotr Skowron, Grzegorz Siebielec, Tamara Jadczyszyn, Tomasz Cencek

Introduction and objective: Natural fertilizers, sewage sludge, digestates, as well as organic fertilizers produced on their basis, can become a source of parasitological contamination of cultivated land. High concentration of invasive forms of parasites in the soil may pose a threat to human and animal health. Therefore, it is necessary to control the hygienic condition of fertilizers and fertilized soils with particular emphasis on parasites. The aim of the study was to compare the effectiveness of methods commonly used for parasitological examination of soil with own methods which were used to develop the standards.

Material and methods: The study was carried out using samples of sandy soil (SS), horticultural mix soil (HS) and peat-based substrate (PS). Each sample was spiked with 100 dyed Ascaris suum eggs and examined with the use of 6 methods: Vasilkova, Dada, Quinn, and 3 methods according to the Polish Standards (PN-19000, PN- 19005, PN-19006). For each variant, 8 repetitions were made.

Results: The largest number of A. suum eggs were found with PN-19006 (mean number of detected eggs was 21.25, 46.50, 23.00 for HS, SS, PS, respectively. Slightly lower results were obtained using PN-19005 - the mean number eggs was 21.25, 36.00, 16.75, respectively. On the other hand, the mean number of A. suum eggs found with the Dada method was about 2-3 times lower than with the PN-19006 - 15.75, 22.50, 6.50 for HS, SS, PS soil, respectively. Other methods were much less effective.

Conclusions: PN-19006 method turned out to be the most effective in detecting A. suum eggs. This method can be used for parasitological examination of soils and can be the basis for developing a system of methods dedicated to testing different types of soils for the presence of nematode eggs.

引言和目的:天然肥料、污水污泥、消化物以及在此基础上生产的有机肥料可能成为耕地寄生虫学污染的来源。土壤中高浓度的侵入性寄生虫可能对人类和动物健康构成威胁。因此,有必要控制肥料和施肥土壤的卫生条件,特别是寄生虫。本研究的目的是比较土壤寄生虫学检查常用方法与制定标准所用方法的有效性。材料和方法:采用沙质土壤(SS)、园艺混合土(HS)和泥炭基质(PS)样品进行研究。每个样品掺入100个染色的蛔虫卵,并根据波兰标准(PN-19000、PN-19005、PN-19006)使用6种方法进行检查:Vasilkova、Dada、Quinn和3种方法。对于每个变体,进行8次重复。结果:用PN-19006发现的A.suum卵数量最多(HS、SS和PS的平均检测卵数分别为21.25、46.50和23.00。使用PN-19005获得的结果略低,平均卵数分别是21.25、36.00和16.75。另一方面,使用Dada方法发现的A.suum卵数比PN-19006低约2-3倍,HS、SS、PS土壤分别为15.75、22.50和6.50效果要差得多。结论:PN-19006法是最有效的毒鸡蛋检测方法。该方法可用于土壤的寄生虫学检查,并可作为开发一套专门测试不同类型土壤是否存在线虫卵的方法系统的基础。
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引用次数: 0
Cross-cultural adaptation of the Contextual Body Image Questionnaire for Athletes for young physically active Polish adults. 波兰年轻体育活跃成年人运动员身体形象情境问卷的跨文化改编。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-04-19 DOI: 10.26444/aaem/162686
Joanna Borowiec, Adam Kantanista, Magdalena Król-Zielińska

Introduction and objective: Individuals who are not professional and competitive athletes but who engage in regular (even daily) physical activity may experience a different body image in the context of physical activity compared with that in everyday life. The Contextual Body Image Questionnaire for Athletes (CBIQA) has been developed to assess aspects of body image within these two dimensions, but has not yet been validated in the Polish population. This study aimed to conduct a cross-cultural adaptation of the CBIQA for physically active Polish adults.

Material and methods: The study sample comprised 90 young Polish adults (49 women and 41 men). All respondents regularly participated in recreational sports. The average age of the sample was 21.4 years. All participants engaged in physical activity at least 3 times per week. The average training experience was 8.6 years. A 3-phase study was conducted: 1) translation of the CBIQA for use in a Polish sample, 2) pretesting and cognitive debriefing, and 3) evaluation of the test-retest reliability. The test-retest interval was 7 days. Interclass correlation coefficients were calculated.

Results: The 1-week test- retest results (ICC) ranged from 0.83-0.94 in the daily life subscales and from 0.86-0.95 in the athletic subscales among all participants. The reliability of the CBIQA was high. The alpha value for the internal consistency of the translated and adapted instrument was 0.91. After the translation and cognitive interview, 3 sentences were reworded to adapt the instrument to Polish culture.

Conclusions: The CBIQA exhibited a high tes-retest reliability and good validity for assessing daily and physical activity-related body image in a Polish population.

引言和目标:不是专业和竞技运动员,但经常(甚至每天)进行体育活动的个人在体育活动中可能会体验到与日常生活不同的身体形象。运动员情境身体形象问卷(CBIQA)已被开发用于评估这两个维度内身体形象的各个方面,但尚未在波兰人群中得到验证。本研究旨在对身体活跃的波兰成年人进行CBIQA的跨文化适应。材料和方法:研究样本包括90名波兰年轻成年人(49名女性和41名男性)。所有受访者都定期参加娱乐性体育活动。样本的平均年龄为21.4岁。所有参与者每周至少进行3次体育活动。平均培训经验为8.6年。进行了一项分三阶段的研究:1)在波兰语样本中使用CBIQA的翻译,2)预测试和认知汇报,以及3)评估重测的可靠性。重测间隔为7天。计算了类间相关系数。结果:所有参与者的1周测试-再测试结果(ICC)在日常生活分量表中的范围为0.83-0.94,在运动分量表中为0.86-0.95。CBIQA的可靠性很高。经翻译和改编的仪器内部一致性的α值为0.91。在翻译和认知访谈后,对3个句子进行了改写,以使该乐器适应波兰文化。结论:CBIQA在评估波兰人群的日常和体育活动相关身体形象方面表现出较高的tes复验信度和良好的有效性。
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引用次数: 0
Lack of major impact of implementation of the Advanced Hybrid Closed Loop System in technologically-naïve patients with Type 1 Diabetes mellitus on their food choices or weight - a one year follow-up. 在技术幼稚的1型糖尿病患者中实施先进的混合闭环系统对他们的食物选择或体重没有重大影响——一年的随访。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-03-09 DOI: 10.26444/aaem/161289
Sabina Krzyżowska, Bartłomiej Matejko, Katarzyna Cyranka, Anna Juza, Beata Kieć-Wilk, Tomasz Klupa

Introduction and objective: The purpose of this follow-up study on the implementation of advanced closed-loop hybrid insulin pumps in people with type 1 diabetes was to assess the impact of introducing this advanced technology on quantitative and qualitative parameters of diet.

Material and methods: 18 patients (8 women and 10 men, mean age 40.9 years) patients using the CE-marked MiniMed 780G AHCL system who completed 1 year of follow-up were included into the study. The research tool was the KomPAN questionnaire with several own questions added, asked in three study periods, concerning the number of meals consumed, general and night snacking, carbohydrate counting, frequency of consumption of various groups of products that affect postprandial glycaemia.

Results: Although the mean body weight of the examined group did not increase significantly (from 75.1 kg at the beginning to 75,9 kg at the end), five various individual scenarios of weight change were observed. The eating habits has not changed, but patients began to consume less products containing simple sugars, e.g. fruit preserves, milk chocolate or fish in sauces (p<0.05). No statistically significant correlation was found between the change in body weight at the end of the study and the average amount of carbohydrates entered into the pump from the entire 12 months (p = 0.460).

Conclusions: The implementation of AHCL system in technology naïve patients, despite offering more freedom of food choices due to better glycaemic control, did not have a significant impact on patients' dietary patterns, also did not result in weight gain. This is important since AHCL system offers more freedom of food choices due to better glycaemic control. However, the longer follow up and the study based on larger population is required to finally address the issue of the impact of AHCL on body mass.

引言和目的:这项关于在1型糖尿病患者中实施先进闭环混合型胰岛素泵的后续研究的目的是评估引入这项先进技术对饮食定量和定性参数的影响。材料和方法:18名患者(8名女性和10名男性,平均年龄40.9岁)使用CE标记的MiniMed 780G AHCL系统,完成1年随访的患者被纳入研究。研究工具是KomPAN问卷,在三个研究期内添加了几个自己的问题,涉及用餐次数、一般和夜间零食、碳水化合物计数、影响餐后血糖的各类产品的消费频率。结果:尽管受试组的平均体重没有显著增加(从开始时的75.1公斤增加到结束时的75.9公斤),但观察到了五种不同的体重变化情况。饮食习惯没有改变,但患者开始减少食用含有单糖的产品,如水果蜜饯,牛奶巧克力或酱汁鱼(结论:AHCL系统在技术幼稚的患者中的实施,尽管由于更好的血糖控制而提供了更多的食物选择自由,但对患者的饮食模式没有显著影响,也没有导致体重增加。这一点很重要,因为AHCL系统由于更好的血压控制而提供更多的食物自由。然而需要基于更大人群的研究来最终解决AHCL对体重的影响问题。
{"title":"Lack of major impact of implementation of the Advanced Hybrid Closed Loop System in technologically-naïve patients with Type 1 Diabetes mellitus on their food choices or weight - a one year follow-up.","authors":"Sabina Krzyżowska,&nbsp;Bartłomiej Matejko,&nbsp;Katarzyna Cyranka,&nbsp;Anna Juza,&nbsp;Beata Kieć-Wilk,&nbsp;Tomasz Klupa","doi":"10.26444/aaem/161289","DOIUrl":"https://doi.org/10.26444/aaem/161289","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The purpose of this follow-up study on the implementation of advanced closed-loop hybrid insulin pumps in people with type 1 diabetes was to assess the impact of introducing this advanced technology on quantitative and qualitative parameters of diet.</p><p><strong>Material and methods: </strong>18 patients (8 women and 10 men, mean age 40.9 years) patients using the CE-marked MiniMed 780G AHCL system who completed 1 year of follow-up were included into the study. The research tool was the KomPAN questionnaire with several own questions added, asked in three study periods, concerning the number of meals consumed, general and night snacking, carbohydrate counting, frequency of consumption of various groups of products that affect postprandial glycaemia.</p><p><strong>Results: </strong>Although the mean body weight of the examined group did not increase significantly (from 75.1 kg at the beginning to 75,9 kg at the end), five various individual scenarios of weight change were observed. The eating habits has not changed, but patients began to consume less products containing simple sugars, e.g. fruit preserves, milk chocolate or fish in sauces (p<0.05). No statistically significant correlation was found between the change in body weight at the end of the study and the average amount of carbohydrates entered into the pump from the entire 12 months (p = 0.460).</p><p><strong>Conclusions: </strong>The implementation of AHCL system in technology naïve patients, despite offering more freedom of food choices due to better glycaemic control, did not have a significant impact on patients' dietary patterns, also did not result in weight gain. This is important since AHCL system offers more freedom of food choices due to better glycaemic control. However, the longer follow up and the study based on larger population is required to finally address the issue of the impact of AHCL on body mass.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A simplified method for determining potential heavy metal leached from sediments of stormwater and combined sewer systems - importance for public health. 一种确定雨水和联合下水道系统沉积物中潜在重金属浸出物的简化方法——对公众健康的重要性。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-08-11 DOI: 10.26444/aaem/170099
Sylwia Duda-Saternus, Justyna Kujawska, Edyta Wojtaś, Aleksandra Kozłowska, Konrad Jamka, Bartosz Szeląg, Roman Babko, Grzegorz Łagód

Introduction and objective: The identification and understanding of interactions between contaminants present in sediments from stormwater and combined sewer systems is a prerequisite for their proper management, and provides a basis for developing effective strategies to minimize their negative impact on humans and the environment. The studypresents the method described in PN-EN 12457-2:2006 as a possible technique for studying the mobility of heavy metals in sediments from stormwater and combined sewer systems.

Material and methods: The presented PN-EN 12457-2:2006 method is a relatively simple technique for preparing extracts for the determination of heavy metals in sediments from stormwater and combined sewer systems, consisting of one-step leaching, which is quick to perform. In addition, it allows determination of the characteristics of the samples to be analyzed, and indicates procedures and tests for evaluating hazardous substances released from solid waste.

Results: The results of the concentrations of leached heavy metals: chromium, copper, nickel, lead and zinc, obtained in the study, corresponded to the concentrations of the exchange fraction of sludge when using the recommended method with sequential extraction (Student's t-test, p=0.263). In the literature review conducted, no papers were found on the application of the leaching method to prepare extracts for the determination of heavy metals in sediments from stormwater and combined sewer systems.

Conclusions: The PN-EN 12457-2:2006 method is capable of providing important data on the potential risks to humans and the environment from the presence of contaminants in sewage sludge.

引言和目标:识别和了解雨水和联合下水道系统沉积物中存在的污染物之间的相互作用是对其进行适当管理的先决条件,并为制定有效策略以最大限度地减少其对人类和环境的负面影响提供了基础。该研究提出了PN-EN 12457-2:2006中描述的方法,作为研究雨水和联合下水道系统沉积物中重金属迁移的可能技术。材料和方法:提出的PN-EN 12457-2:2006方法是一种相对简单的提取技术,用于测定雨水和联合下水道系统沉积物中的重金属,包括一步浸出,执行速度快。此外,它还可以确定待分析样品的特性,并指示评估固体废物释放的危险物质的程序和测试。结果:研究中获得的浸出重金属铬、铜、镍、铅和锌的浓度结果与使用推荐的顺序提取方法时污泥交换分数的浓度相对应(Student t检验,p=0.263)。在进行的文献综述中,应用浸提法制备提取液测定雨水和合流制下水道系统沉积物中重金属的文献较少。结论:PN-EN 12457-2:2006方法能够提供关于污水污泥中污染物对人类和环境的潜在风险的重要数据。
{"title":"A simplified method for determining potential heavy metal leached from sediments of stormwater and combined sewer systems - importance for public health.","authors":"Sylwia Duda-Saternus,&nbsp;Justyna Kujawska,&nbsp;Edyta Wojtaś,&nbsp;Aleksandra Kozłowska,&nbsp;Konrad Jamka,&nbsp;Bartosz Szeląg,&nbsp;Roman Babko,&nbsp;Grzegorz Łagód","doi":"10.26444/aaem/170099","DOIUrl":"https://doi.org/10.26444/aaem/170099","url":null,"abstract":"<p><strong>Introduction and objective: </strong>The identification and understanding of interactions between contaminants present in sediments from stormwater and combined sewer systems is a prerequisite for their proper management, and provides a basis for developing effective strategies to minimize their negative impact on humans and the environment. The studypresents the method described in PN-EN 12457-2:2006 as a possible technique for studying the mobility of heavy metals in sediments from stormwater and combined sewer systems.</p><p><strong>Material and methods: </strong>The presented PN-EN 12457-2:2006 method is a relatively simple technique for preparing extracts for the determination of heavy metals in sediments from stormwater and combined sewer systems, consisting of one-step leaching, which is quick to perform. In addition, it allows determination of the characteristics of the samples to be analyzed, and indicates procedures and tests for evaluating hazardous substances released from solid waste.</p><p><strong>Results: </strong>The results of the concentrations of leached heavy metals: chromium, copper, nickel, lead and zinc, obtained in the study, corresponded to the concentrations of the exchange fraction of sludge when using the recommended method with sequential extraction (Student's t-test, p=0.263). In the literature review conducted, no papers were found on the application of the leaching method to prepare extracts for the determination of heavy metals in sediments from stormwater and combined sewer systems.</p><p><strong>Conclusions: </strong>The PN-EN 12457-2:2006 method is capable of providing important data on the potential risks to humans and the environment from the presence of contaminants in sewage sludge.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic approach to a paediatric patient with Wiedemann-Steiner syndrome with de novo missense variant in the KMT2A gene - a case report. 一例KMT2A基因新发错义变异的Wiedemann-Steiner综合征患儿的诊断方法——一例报告。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-05-08 DOI: 10.26444/aaem/163063
Gabriela Ręka, Katarzyna Wojciechowska, Monika Lejman

Introduction: Wiedemann-Steiner syndrome is caused by mutations in the KMT2A gene (11q23.3). It might be inherited autosomal dominant or appear de novo. Features described in the syndrome include developmental delay, short stature, hypotonia, hypertrichosis, facial dysmorphic features, and intellectual disability.

Case report: A boy aged 5.5 months was admitted to the Genetics Outpatient Clinic due to delayed psychomotor development. Microsomia, hypotonia, joint laxity, and facial dysmorphic features were noticed. No genomic imbalance was found in microarray, based on comparative genomic hybridization. The c.3528G>T variant of the KMT2A gene was identified on chromosome 11 of the missense type in next-generation sequencing. The reasons for phenotypic features were confirmed in genetic research.

Conclusions: Wiedemann-Steiner syndrome has a variable clinical phenotype. There is a strong need to pay attention to phenotypic features that may suggest the syndrome and refer patients for appropriate genetic diagnostics.

引言:Wiedemann-Steiner综合征是由KMT2A基因(11q23.3)突变引起的。它可能是常染色体显性遗传或新发。该综合征的特征包括发育迟缓、身材矮小、张力减退、多毛、面部畸形和智力残疾。病例报告:一名5.5个月大的男孩因精神运动发育迟缓而住进遗传学门诊。观察到有小眼、张力减退、关节松弛和面部畸形特征。基于比较基因组杂交,在微阵列中没有发现基因组失衡。在下一代测序中,KMT2A基因的c.3528G>T变体在11号染色体上被鉴定为错义型。表型特征的原因已在遗传学研究中得到证实。结论:Wiedemann-Steiner综合征具有多变的临床表型。强烈需要注意可能提示该综合征的表型特征,并将患者转诊进行适当的遗传诊断。
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引用次数: 0
Leprosy - neglected tropical disease in Pygmies inhabiting Central African Republic. 麻风——居住在中非共和国的俾格米人被忽视的热带疾病。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-03-07 DOI: 10.26444/aaem/161465
Emilia Bylicka-Szczepanowska, Regina B Podlasin, Krzysztof Korzeniewski

Leprosy is a neglected tropical disease that is still present worldwide despite efforts aimed at elimination of the disease. The BaAka Pygmy community inhabiting rural areas in the Central African Republic is one of the most leprosy-vulnerable populations. The aim of the study was to assess the prevalence of leprosy in the BaAka Pygmy population. People living in the Dzanga Sangha protected area were regularly visited by a mobile clinic in 2019/2020. The diagnosis was based on the clinical manifestation of the disease. Deformations of skin and extremities were assessed. In a 12-month period 26 cases of leprosy were diagnosed and 25 patients received treatment. 24 of those patients were BaAka Pygmies, 10 were women, 7 were children under 15 years old and 8 were diagnosed with grade 2 disability. Presented data shows that leprosy in Dzanga Sangha region is not well controlled due to the high transmission rate. Efforts to diagnose and report new leprosy cases should be intensified.

麻风病是一种被忽视的热带疾病,尽管努力消除这种疾病,但它仍然存在于世界各地。居住在中非共和国农村地区的BaAka Pygmy社区是最易受麻风病影响的人群之一。这项研究的目的是评估巴阿卡-俾格米人的麻风病流行率。2019/2020年,一家流动诊所定期探访居住在Dzanga Sangha保护区的人们。诊断是基于该疾病的临床表现。评估皮肤和四肢的变形。在12个月的时间里,诊断出26例麻风病,25名患者接受了治疗。其中24名患者是BaAka俾格米人,10名是妇女,7名是15岁以下的儿童,8名被诊断为2级残疾。现有数据显示,由于传播率高,赞加-桑哈地区的麻风病没有得到很好的控制。应加紧努力诊断和报告新的麻风病病例。
{"title":"Leprosy - neglected tropical disease in Pygmies inhabiting Central African Republic.","authors":"Emilia Bylicka-Szczepanowska,&nbsp;Regina B Podlasin,&nbsp;Krzysztof Korzeniewski","doi":"10.26444/aaem/161465","DOIUrl":"https://doi.org/10.26444/aaem/161465","url":null,"abstract":"<p><p>Leprosy is a neglected tropical disease that is still present worldwide despite efforts aimed at elimination of the disease. The BaAka Pygmy community inhabiting rural areas in the Central African Republic is one of the most leprosy-vulnerable populations. The aim of the study was to assess the prevalence of leprosy in the BaAka Pygmy population. People living in the Dzanga Sangha protected area were regularly visited by a mobile clinic in 2019/2020. The diagnosis was based on the clinical manifestation of the disease. Deformations of skin and extremities were assessed. In a 12-month period 26 cases of leprosy were diagnosed and 25 patients received treatment. 24 of those patients were BaAka Pygmies, 10 were women, 7 were children under 15 years old and 8 were diagnosed with grade 2 disability. Presented data shows that leprosy in Dzanga Sangha region is not well controlled due to the high transmission rate. Efforts to diagnose and report new leprosy cases should be intensified.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41146573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of fine particulate matter 2.5 on hospitalization for upper respiratory tract infections in Lanzhou urban industrial area, China. 中国兰州城市工业区细颗粒物2.5对上呼吸道感染住院治疗的影响。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-09-11 DOI: 10.26444/aaem/171499
Guangyu Zhai, Lei Zhang

Introduction and objective: Abundant evidence has shown that an increase in the concentration of fine particulate matter 2.5 (PM2.5) leads to a simultaneous increase in the incidence of respiratory diseases. Xigu District is the main industrial district of Lanzhou, located in Lanzhou City in northwest China and central Gansu Province. Because of limited research and data in the region, the impact of PM2.5 on human health has not been systematically recognized. The aim of the study was to investigate the relationship between PM2.5 pollution and upper respiratory tract infections in urban industrial areas of Lanzhou City.

Material and methods: Data on outpatient visits, air pollutants, and meteorological indices were collected in the Xigu District of Lanzhou City from 1 January 2013 - 31 December 2019. A generalized additive model was used to evaluate the association between PM2.5 and outpatient visits for upper respiratory tract infections.

Results: The results show that PM2.5 had the greatest impact on outpatient visits for upper respiratory tract infections on 7 cumulative lag days. At cumulative lag days 1, 3, and 5, the effects gradually increased. In the subgroup analysis, the effect of PM2.5 on visits for upper respiratory tract infections was significantly influenced by gender. Men were more susceptible to PM2.5 pollution.

Conclusions: An increase in atmospheric PM2.5 concentration was associated with an increase in visits for upper respiratory tract infections with the lag effect. The obtained results can provide a reference for the development of prevention strategies to protect the population from the adverse effects of PM2.5 pollution.

引言和目的:大量证据表明,细颗粒物2.5(PM2.5)浓度的增加会导致呼吸道疾病的发病率同时增加。西固区是兰州的主要工业区,位于中国西北部的兰州市和甘肃省中部。由于该地区的研究和数据有限,PM2.5对人类健康的影响尚未得到系统的认识。本研究旨在调查兰州市城市工业区PM2.5污染与上呼吸道感染的关系。材料和方法:收集2013年1月1日至2019年12月31日兰州市西固区门诊、空气污染物和气象指标的数据。使用广义加性模型来评估PM2.5与上呼吸道感染门诊就诊之间的关系。结果:PM2.5对上呼吸道感染门诊就诊影响最大的是7个累积滞后日。在累积滞后第1、3和5天,影响逐渐增加。在亚组分析中,PM2.5对上呼吸道感染就诊的影响受性别的显著影响。男性更容易受到PM2.5污染的影响。结论:大气PM2.5浓度的增加与上呼吸道感染就诊次数的增加有关,具有滞后效应。研究结果可为制定预防策略以保护人群免受PM2.5污染的不利影响提供参考。
{"title":"Impact of fine particulate matter 2.5 on hospitalization for upper respiratory tract infections in Lanzhou urban industrial area, China.","authors":"Guangyu Zhai,&nbsp;Lei Zhang","doi":"10.26444/aaem/171499","DOIUrl":"https://doi.org/10.26444/aaem/171499","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Abundant evidence has shown that an increase in the concentration of fine particulate matter 2.5 (PM2.5) leads to a simultaneous increase in the incidence of respiratory diseases. Xigu District is the main industrial district of Lanzhou, located in Lanzhou City in northwest China and central Gansu Province. Because of limited research and data in the region, the impact of PM2.5 on human health has not been systematically recognized. The aim of the study was to investigate the relationship between PM2.5 pollution and upper respiratory tract infections in urban industrial areas of Lanzhou City.</p><p><strong>Material and methods: </strong>Data on outpatient visits, air pollutants, and meteorological indices were collected in the Xigu District of Lanzhou City from 1 January 2013 - 31 December 2019. A generalized additive model was used to evaluate the association between PM2.5 and outpatient visits for upper respiratory tract infections.</p><p><strong>Results: </strong>The results show that PM2.5 had the greatest impact on outpatient visits for upper respiratory tract infections on 7 cumulative lag days. At cumulative lag days 1, 3, and 5, the effects gradually increased. In the subgroup analysis, the effect of PM2.5 on visits for upper respiratory tract infections was significantly influenced by gender. Men were more susceptible to PM2.5 pollution.</p><p><strong>Conclusions: </strong>An increase in atmospheric PM2.5 concentration was associated with an increase in visits for upper respiratory tract infections with the lag effect. The obtained results can provide a reference for the development of prevention strategies to protect the population from the adverse effects of PM2.5 pollution.</p>","PeriodicalId":50970,"journal":{"name":"Annals of Agricultural and Environmental Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between apparent temperature and hypertension hospital admissions: a case study in rural areas in western China. 表观温度与高血压住院人数的关系:中国西部农村地区的一项个案研究。
IF 1.7 4区 医学 Q2 Agricultural and Biological Sciences Pub Date : 2023-09-28 Epub Date: 2023-05-11 DOI: 10.26444/aaem/163325
Guangyu Zhai, Yuan Wang, Kuan Zhang, Yiwen Tian

Introduction and objective: Although it has previously been shown that temperature is associated with cardiovascular disease, no investigations exploring the association between apparent temperature (AT) and hypertension in farmers in Zhangye and Longnan, Gansu Province, China, have been undertaken. As hypertension is a commonly known risk factor for cardiovascular disease, the relationship between apparent temperature (AT) and hypertension is examined in Zhangye and Longnan to provide advice to local governments on preventive measures.

Material and methods: Daily data and weather conditions were collected in Zhangye and Longnan from 2014-2015. The Poisson generalized linear model and the distributed lag nonlinear model (DLNM) were combined to investigate the relationship between AT and hypertension in hospital admissions in the study areas.

Results: A non-linear relationship between AT and hypertension in hospital admissions in both Zhangye and Longnan were recorded. The cold effects were stronger in Zhangye than that in Longnan for both study group and subgroups. The heat effects were more deleterious for the entire study group, female subgroup and adult subgroup in Longnan, but stronger for the male subgroup and elderly subgroup in Zhangye.

Conclusions: This investigation indicates that AT has adverse impacts on hypertension hospital admissions in Zhangye and Longnan, especially under low AT exposure levels. The results from this study may promote the formulation of further prevention measures for hypertension disease.

引言和目的:尽管先前已经表明温度与心血管疾病有关,但尚未对张掖和甘肃陇南农民的表观温度(AT)与高血压之间的关系进行调查。由于高血压是心血管疾病的常见危险因素,在张掖和陇南两地对表观温度(AT)与高血压的关系进行了研究,为当地政府提供预防措施建议。材料和方法:收集张掖和陇南2014-2015年的日常数据和天气状况。将泊松广义线性模型和分布滞后非线性模型(DLNM)相结合,研究了AT与研究地区住院高血压之间的关系。结果:张掖和陇南两地住院患者的AT与高血压呈非线性关系。研究组和亚组的冷效应在张掖均强于陇南。热效应对整个研究组、陇南女性亚组和成年亚组的危害更大,而对张掖男性亚组和老年亚组的影响更大。这项研究的结果可能有助于制定进一步的高血压疾病预防措施。
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Annals of Agricultural and Environmental Medicine
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