Langmuir最新文献_第9页

A Stable, Molecularly Imprinted Porous Hydrogel Membrane via Chemical Cross-Linking for Glyphosate Detection 一种稳定的，通过化学交联的分子印迹多孔水凝胶膜用于草甘膦检测

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c05698

Wen Xin,Yajun Ren,Xiaofeng Song,Honghui Teng,Mingyue Jin,Menghao Tian

The stability of molecularly imprinted membranes (MIMs) is a critical factor influencing their reusability and detection performance. To overcome stability limitations, a robust porous imprinted hydrogel membrane (porous PVA/HS-β-CD/Ag/MIPs) was developed by grafting recognition sites onto a porous framework. The membrane was synthesized through a multistep process: (i) A porous hydrogel matrix was formed via freeze–thaw-induced cross-linking between poly(vinyl alcohol) (PVA) and thiolated β-cyclodextrin (HS-β-CD), combined with the use of a pore-forming agent; (ii) the membrane was functionalized as a surface-enhanced Raman scattering (SERS) substrate through in situ reduction of silver ions (from AgNO3); (iii) glyphosate (GLY)-imprinted polymers were anchored via precipitation polymerization, utilizing HS-β-CD as grafting sites to achieve specific recognition and detection. Morphological and stability analyses demonstrated that the SERS-imprinted porous membrane exhibits high structural integrity, retaining 94.89% of its detection capability after 12 h under continuous water flow. This study introduces a robust covalent anchoring strategy between the imprinting layer and the substrate to form chemical cross-linking, providing an effective pathway for designing high-performance, long-lifespan molecularly imprinted membranes.

分子印迹膜的稳定性是影响其重复使用和检测性能的关键因素。为了克服稳定性的限制，通过将识别位点嫁接到多孔框架上，开发了一种坚固的多孔印迹水凝胶膜（多孔PVA/HS-β-CD/Ag/MIPs）。采用多步骤合成膜：(i)通过冻融诱导的聚乙烯醇（PVA）与巯基化β-环糊精（HS-β-CD）交联形成多孔水凝胶基质，并结合成孔剂的使用；（ii）通过原位还原银离子（来自AgNO3），膜被功能化为表面增强拉曼散射（SERS）底物；（iii）通过沉淀聚合固定草甘膦（GLY）印迹聚合物，利用HS-β-CD作为接枝位点实现特异性识别和检测。形态学和稳定性分析表明，sers印迹多孔膜具有较高的结构完整性，在连续水流作用12 h后仍能保持94.89%的检测能力。本研究引入了一种强大的共价锚定策略，在印迹层和底物之间形成化学交联，为设计高性能、长寿命的分子印迹膜提供了有效途径。

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引用次数: 0

Nonfaradaic Ionic Thermoelectric Conversion: The Soret Effect or Asymmetric Interfacial Ion Rearrangement? 非法拉第离子热电转换：索雷效应还是不对称界面离子重排？

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c06707

Zhiwu Chen,Yapei Wang

The utilization of low-grade waste heat and the demand for detecting physical signals with the presence of heat as their manifestation, have driven the refinement and advancement of thermoelectric concepts in theory, materials, devices, and applications. Ionic thermoelectric materials, characterized by low cost, flexibility, and high ionic Seebeck coefficients, are emerging as the next-generation medium for the utilization and conversion of thermal energy. The Soret effect, also known as ion thermal diffusion is broadly recognized as the primary driving force for energy conversion in ionic thermoelectric materials. Significant efforts have been dedicated to material chemistry design, theoretical modeling, and thermoelectric voltage enhancement within the theoretical framework of the Soret effect. However, tracing the evolution of ionic thermoelectric concepts, another theoretical perspective has persisted throughout. Although widely overlooked, the equally critical electrode–electrolyte interface has increasingly been proven to be central to the generation of thermoelectric voltage, and the derived asymmetric interfacial ion rearrangement effect stands as a hidden gem in this field. Given the lack of consensus in the ionic thermoelectric theory, the organization of this review is both timely and necessary. This article will comprehensively review the historical development and relevant theories of nonfaradaic ionic thermoelectric conversion, and thoroughly analyze the mechanisms and relative contributions of the Soret effect and asymmetric interfacial ion rearrangement. The new opportunities presented by the theory of asymmetric interfacial ion rearrangement for the structure and performance of thermoelectric devices will be highlighted. It will conclude by outlining the key challenges and research priorities facing this field in its future development.

低品位废热的利用和以热为表现形式检测物理信号的需求，推动了热电概念在理论、材料、设备和应用方面的完善和进步。离子热电材料具有成本低、柔韧性强、离子塞贝克系数高等特点，正在成为下一代热能利用和转化的介质。索雷特效应，也被称为离子热扩散，被广泛认为是离子热电材料中能量转换的主要驱动力。在索莱特效应的理论框架内，人们致力于材料化学设计、理论建模和热电电压增强。然而，追踪离子热电概念的演变，另一种理论观点一直贯穿始终。尽管被广泛忽视，但同样重要的电极-电解质界面已经越来越多地被证明是热电电压产生的核心，而由此衍生的不对称界面离子重排效应是这一领域的一块隐藏的宝石。鉴于离子热电理论缺乏共识，组织这次综述是及时和必要的。本文将全面回顾非法拉第离子热电转换的历史发展和相关理论，深入分析Soret效应和不对称界面离子重排的机理及其相关贡献。不对称界面离子重排理论为热电器件的结构和性能提供了新的机遇。最后将概述该领域在未来发展中面临的主要挑战和研究重点。

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引用次数: 0

Chitosan-Coated Sewage Sludge–Coal Gangue Biochar Spheres for Efficient Cr(VI) Removal from Water and Soil 壳聚糖包被污水污泥-煤矸石生物炭球高效去除水中和土壤中的铬

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c05407

Xiao Ma,Xingyu Liu,Hongtao Wu,Yuxuan Li,Junlun Mei,Qiao Xiong

A chitosan-coated biochar sphere (BC-CG-CT) was fabricated via facile copyrolysis of municipal sewage sludge (SS) and coal gangue (CG), followed by ionic gelation encapsulation. Under optimized conditions (650 °C pyrolysis, 100 min, SS:CG = 1:1), BC-CG-CT achieved a maximum Cr(VI) adsorption capacity of 23.85 mg·g–1 and removal rates above 97% at pH 5 in aqueous systems. Kinetic and isotherm studies revealed a dominant pseudo-first-order behavior, monolayer adsorption, and energetically favorable interactions. Thermodynamic analysis indicated spontaneous, endothermic adsorption. In soil incubation tests (90 days, up to 300 g·kg–1 dosage), BC-CG-CT reduced soluble Cr(VI) by up to 57.6%, shifted Cr fractionation from labile (EX/CB) to stable (OX/RS) pools, elevated soil pH and TOC, and suppressed CaCl2-extractable Cr to below 0.1 mg·kg–1. Mechanistic investigations combining SEM-EDS, XRD, FTIR, and XPS confirmed synergistic immobilization via pore-filling, electrostatic adsorption, Cr(VI) reduction by electron-donor groups, and complexation/precipitation. The robust spherical morphology enhances recoverability and reuse. This work demonstrates a promising and sustainable strategy for simultaneous remediation of Cr(VI) in water and soil, leveraging industrial and municipal waste valorization.

以城市污水污泥（SS）和煤矸石（CG）为原料，经易溶共解并进行离子凝胶包封制备壳聚糖包被生物炭球（BC-CG-CT）。在优化条件下（650℃热解，100 min, SS:CG = 1:1）， BC-CG-CT在pH为5的水溶液体系中Cr（VI）的最大吸附量为23.85 mg·g-1，去除率超过97%。动力学和等温线研究揭示了主要的伪一级行为、单层吸附和能量有利的相互作用。热力学分析表明是自发吸热吸附。在土壤培养试验（90天，最高300 g·kg-1剂量）中，BC-CG-CT降低可溶性Cr（VI）高达57.6%，将Cr从不稳定（EX/CB）池转移到稳定（OX/RS）池，提高土壤pH和TOC，并将cac2可提取的Cr抑制到0.1 mg·kg-1以下。结合SEM-EDS， XRD， FTIR和XPS的机理研究证实了通过孔隙填充，静电吸附，电子给体基团还原Cr（VI）和络合/沉淀的协同固定作用。坚固的球形形貌增强了可恢复性和重用性。这项工作表明，利用工业和城市废物增值，同时修复水和土壤中的Cr（VI）是一种有希望和可持续的策略。

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引用次数: 0

Lufenuron Dual-Carrier Nanoformulation: Controlled Release and Systemic Translocation viaβ-Cyclodextrin Octadecanoate and Urea-Formaldehyde Resin. 氟虫腈双载体纳米配方：经β-十八酸环糊精和脲醛树脂的控释和全身转运。

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c05447

Zhiping Liu, Jiansheng Li, Yanmin Huang, Weiguo Li, Chunrui Cai, Qiang Hu, Yanlin Chen, Jianguo Cui

Through dual encapsulation of the insecticide lufenuron with β-cyclodextrin octadecanoate and urea-formaldehyde resin, a lufenuron@β-cyclodextrin octadecanoate/urea formaldehyde resin (LF@β-CDs/UF) nanoformulation was prepared. This dual-carrier synergy significantly prolonged the release cycle of lufenuron and enhanced environmental adaptability. Results demonstrated that under 25 °C and pH 7 conditions, its release cycle reached 324 h in 20% methanol-water, representing a 1.5-fold prolongation compared to the single-carrier lufenuron@β-cyclodextrin octadecanoate (LF@β-CDs) nanoformulation, with a pH/temperature-responsive release behavior. The photolysis half-life (t₅₀) was extended by 1.6- and 9.3-fold compared to LF@β-CDs (51 h) and lufenuron (LF) microemulsion (8.9 h), respectively. At a low concentration of 6.25 mg/L, the mortality rate against Spodoptera litura reached 73.33%, significantly outperforming LF@β-CDs (29.33%) and LF microemulsion (5.33%). The LF@β-CDs/UF also substantially prolonged insecticidal duration and enhanced the systemic translocation of lufenuron in plants. Biosafety assessment showed that it significantly reduced ecological toxicity, increasing rice seed germination rates from 40.7% (microemulsion) to 71.3% at 400 mg/L seed-soaking concentration, while elevating the acute toxicity LC₅₀ value in zebrafish by 4.4-fold, demonstrating substantially comparative eco-friendliness compared to conventional formulations. This dual-carrier technology, via structure-function synergy, provides an innovative solution to challenges such as low pesticide utilization efficiency and high environmental risks.

采用β-十八酸环糊精和脲醛树脂对杀虫剂虫腈进行双包封，制备了虫腈@β-十八酸环糊精/脲醛树脂（LF@β-CDs/UF）纳米配方。这种双载体协同作用显著延长了氟虫腈的释放周期，增强了环境适应性。结果表明，在25°C和pH 7条件下，其在20%甲醇-水中的释放周期达到324 h，比单载体lufenuron@β-环糊精十八酸酯（LF@β-CDs）纳米制剂的释放周期延长1.5倍，且具有pH/温度响应行为。光解半衰期（t50）分别比LF@β- cds （51 h）和lufenuron （LF）微乳（8.9 h）延长了1.6倍和9.3倍。在低浓度6.25 mg/L下，对斜纹夜蛾的死亡率为73.33%，显著优于LF@β- cd（29.33%）和LF微乳（5.33%）。LF@β-CDs/UF也显著延长了杀虫持续时间，增强了虫腈在植物体内的系统转运。生物安全评价表明，该配方显著降低了生态毒性，在400 mg/L种子浸泡浓度下，水稻种子发芽率从40.7%（微乳剂）提高到71.3%，对斑马鱼的急性毒性LC50值提高了4.4倍，与传统配方相比具有显著的生态友好性。这种双载体技术通过结构-功能协同作用，为解决农药利用效率低、环境风险大等挑战提供了创新的解决方案。

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引用次数: 0

Formation of the Pattern of Al–Zn Dendrites Driven by Solid–Liquid Interfacial Energy 固液界面能驱动下Al-Zn枝晶模式的形成

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c06494

Lele Chen,Chenglin Huang,Fang Luo,Sansan Shuai,Lei Wang,Tao Hu,Yang Yang,Jiang Wang,Zhongming Ren

Solid–liquid interfacial energy critically governs microstructural evolution and the functional properties of materials during phase transition. Here, we quantitatively characterize the anisotropy of solid–liquid interfacial energy in an Al-30 wt % Zn hypoeutectic alloy using the improved equilibrium shape method, X-ray microcomputed tomography (CT), and digital image analysis. We obtained the two-dimensional (ε4) and three-dimensional (ξ1, ξ2) anisotropy parameters by fitting droplet shapes with Fourier series and cubic harmonics. The interfacial energy is largest along the ⟨100⟩ and ⟨110⟩ directions, while the interfacial stiffness is smallest along the same directions. The near equivalence of stiffness between the ⟨100⟩ and ⟨110⟩ directions suppresses stable tip selection, destabilizes the growth front, and promotes hyperbranched, seaweed-like morphologies. This study provides quantitative evidence linking interfacial anisotropy to dendrite pattern formation and offers mechanistic insight into the morphological instability of Al–Zn alloys.

固液界面能对相变过程中材料的微观结构演变和功能特性起着至关重要的作用。在这里，我们使用改进的平衡形状法、x射线微计算机断层扫描（CT）和数字图像分析，定量表征了al - 30wt % Zn亚共晶合金固液界面能的各向异性。利用傅里叶级数和三次谐波对液滴形状进行拟合，得到二维（ε4）和三维（ξ1, ξ2）各向异性参数。沿⟨100⟩和⟨110⟩方向的界面能最大，而沿相同方向的界面刚度最小。⟨100⟩和⟨110⟩方向之间的接近等效的刚度抑制了稳定的尖端选择，使生长前沿不稳定，并促进了过度分支的海藻状形态。该研究为界面各向异性与枝晶模式形成之间的联系提供了定量证据，并为Al-Zn合金的形态不稳定性提供了机制见解。

引用次数: 0

Bicarbonate-Mediated Generation of H2O2, 1O2, and OH* at the Hydrophobic Gas–Water Interface and Its Underlying Mechanism 氢碳酸钠在疏水气-水界面上介导H2O2、1O2和OH*的生成及其潜在机制

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-02 DOI: 10.1021/acs.langmuir.5c05232

Chenying Wang,Sangyeon Lee,Vidhya Chakrapani

Spontaneous generation of reactive oxygen species (ROS), such as H2O2, OH*, and O2–*, is known to occur at aqueous aerosol microdroplets or gas microbubbles in bulk water. However, the suggested mechanisms of their formation remain contentious because they posit the breaking of highly stable water bonds. In addition, the primary ROS that is the source for other ROS has also not been established. Herein, we evaluate ROS generation in much simpler macroscopic gas bubbles in the bulk electrolyte. Through in situ studies with electrolytes containing different anions (CO32–, HCO3–, SO42–, H2PO4–, and Cl–), cations (Na+, K+, and Li+), and pH and sparged with gases (O2, CH4, N2, and CO2), we show that ROS generation occurs through the hitherto unrecognized activation of CO2/HCO3–/CO32– that is present inadvertently in all air-exposed aqueous system. In addition, ROS-specific scavenging studies show that H2O2 is the primary ROS produced that serves as the source for OH*, O2–*, and 1O2 generation. The combined evidence suggests that the underlying mechanism may be much more complex than simple bond breakage; rather, it may be electrochemical in origin, with coupled sets of reduction/oxidation reactions occurring at the bubble/water interface.

活性氧（ROS）的自发生成，如H2O2、OH*和O2 - *，已知发生在散装水中的水性气溶胶微滴或气体微泡中。然而，它们的形成机制仍然存在争议，因为它们假设了高度稳定的水键的断裂。此外，作为其他活性氧来源的主要活性氧也尚未确定。在这里，我们评估了在散装电解质中更简单的宏观气泡中ROS的生成。通过对含有不同阴离子（CO32 -、HCO3 -、SO42 -、H2PO4 -和Cl -）、阳离子（Na+、K+和Li+）和pH以及气体（O2、CH4、N2和CO2）的电解质的原位研究，我们发现ROS的产生是通过迄今为止未被识别的CO2/HCO3 - /CO32 -的激活发生的，这种激活在所有暴露于空气的水系统中都是不经意存在的。此外，ROS特异性清除研究表明H2O2是产生的主要ROS，是OH*、O2 - *和1O2生成的来源。综合证据表明，潜在的机制可能比简单的键断裂复杂得多；相反，它可能是电化学的起源，在气泡/水界面上发生了耦合的还原/氧化反应。

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引用次数: 0

Engineering Low-Tortuosity Flake-Like Graphitic Carbon via Molten-Salt-Mediated Magnesiothermic Reduction for Lithium Metal Anodes 熔融盐镁热还原法制备低弯曲片状石墨炭的研究

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-01 DOI: 10.1021/acs.langmuir.5c06766

Min Seok Kang,Yejun Ham,Won Cheol Yoo

Graphite offers attractive properties for lithium-metal hosting, including high electrical conductivity, chemical stability, and mechanical robustness, but its dense structure, low porosity, and basal-plane lithiophobicity hinder uniform Li plating. These limitations cause high nucleation barriers and uneven ion transport, rendering conventional graphite ineffective as a practical Li-metal host. Here, we introduce a molten NaCl─assisted low-temperature (650–950 °C) magnesiothermic reduction strategy that reconstructs polymer spheres into flake-like porous multilayered graphene (FMG) with highly aligned graphitic layers, hierarchical meso–macroporosity, and low tortuosity (∼3). The molten salt acts as both a thermal reservoir and structure-directing medium, moderating the exothermic Mg–oxygen reaction, suppressing Mg volatilization, and enabling facet-selective graphitic reorganization inaccessible through conventional reduction routes. As a Li host, FMG achieves uniform Li nucleation with an ultralow overpotential (20 mV), long-term symmetric cycling over 3000 h, and high Coulombic efficiency (98.2% over 400 cycles). LFP||FMG@Li full cells further demonstrate stable capacity retention, underscoring how molten-salt-driven structural engineering transforms graphite from an intrinsically incompatible material into an architecturally optimized host for high-energy lithium-metal batteries.

石墨具有高导电性、化学稳定性和机械稳健性等优点，但其致密的结构、低孔隙率和基面疏石性阻碍了锂镀层的均匀性。这些限制导致高成核屏障和不均匀的离子传输，使得传统石墨无法作为实用的锂金属宿主。在这里，我们引入了熔融NaCl辅助的低温（650-950℃）镁热还原策略，该策略将聚合物球体重建为片状多孔多层石墨烯（FMG），具有高度排列的石墨层，分层的中宏观孔隙度和低扭曲度（~ 3）。熔盐既是热储层，也是结构导向介质，减缓了放热Mg -氧反应，抑制了Mg的挥发，并实现了常规还原途径无法实现的面选择性石墨重组。作为锂寄主，FMG能以超低过电位（20 mV）、3000 h以上的长时间对称循环和高达98.2%的库仑效率（400次循环）实现均匀的锂成核。LFP||FMG@Li全电池进一步展示了稳定的容量保持，强调了熔融盐驱动的结构工程如何将石墨从本质上不相容的材料转变为高能量锂金属电池的结构优化主体。

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引用次数: 0

Tuning Linkers in Azo-Linked Porphyrin-Based Porous Organic Polymers for Enhanced CO2 Capture 偶氮连接卟啉基多孔有机聚合物的连接剂调谐增强CO2捕获

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-01 DOI: 10.1021/acs.langmuir.5c05572

Matija Popović, Tea Frey, Mladen Borovina, Ivan Kodrin, Ivana Biljan

The increased concentration of atmospheric CO₂ and its impact on the environment drive the search for new materials that can capture and store this greenhouse gas effectively. Porous organic polymers (POPs) are very promising materials for this task because of their stability and the tunability of their pore structure and chemistry. In this study, we synthesized a series of azo-linked porphyrin-based porous organic polymers (APPs) using either heteroatom-containing linkers (hydroxylated biphenyl in APP-BP-OH and carbonyl-bearing anthraquinone in APP-AQ) or sterically hindered linkers (methylated biphenyl and phenyl in APP-BP-Me and APP-Ph-Me, respectively). Structural characterization confirmed the formation of azo linkages and the amorphous nature of the frameworks, while thermal analysis showed that APPs are stable up to at least 200 °C. Gas sorption studies revealed notable differences in porosity and CO₂ uptake. APP-Ph-Me exhibited the largest surface area (673 m² g^–1), whereas APP-BP-OH had a smaller surface area (488 m² g^–1) but adsorbed more CO₂ (49 mg g^–1) compared to APP-Ph-Me (41 mg g^–1). These results illustrate that CO₂ adsorption in APPs is governed by not only the surface area but also the chemical environment. Nitrogen-rich porphyrin and azo moieties play a dominant role, while polar hydroxyl groups and biphenyl linkers provide additional contributions. Computational results supported these findings, indicating that hydroxyl and carbonyl groups create favorable binding sites, while methyl groups limit accessibility to porphyrin and azo regions. Overall, our results highlight how linker design and functionalization directly influence porosity and adsorption performance and offer useful guidelines for the development of new POPs for CO₂ capture.

大气中二氧化碳浓度的增加及其对环境的影响促使人们寻找能够有效捕获和储存这种温室气体的新材料。多孔有机聚合物（POPs）由于其孔隙结构和化学性质的稳定性和可调性，是一种非常有前途的材料。在本研究中，我们使用含杂原子的连接剂（APP-BP-OH中的羟基联苯和APP-AQ中的羰基蒽醌）或位阻连接剂（APP-BP-Me和APP-Ph-Me中的甲基化联苯和苯基）合成了一系列偶氮连接的卟啉基多孔有机聚合物（APPs）。结构表征证实了偶氮键的形成和框架的无定形性质，而热分析表明app在至少200°C下是稳定的。气体吸附研究揭示了孔隙度和CO2吸收的显著差异。APP-Ph-Me的比表面积最大（673 m2 g-1），而APP-BP-OH比APP-Ph-Me的比表面积小（488 m2 g-1），但比APP-Ph-Me吸附了更多的CO2 （49 mg g-1）。这些结果表明，二氧化碳在APPs中的吸附不仅受表面积的影响，还受化学环境的影响。富氮卟啉和偶氮基团起主导作用，而极性羟基和联苯连接提供额外的贡献。计算结果支持这些发现，表明羟基和羰基创造了有利的结合位点，而甲基限制了卟啉和偶氮区域的可及性。总的来说，我们的研究结果强调了连接剂的设计和功能化如何直接影响孔隙度和吸附性能，并为开发用于CO2捕获的新型持久性有机污染物提供了有用的指导。

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引用次数: 0

Interfacial Wear Reduction of Porous CoNiCrFeMn High-Entropy Alloys: An Atomic-Scale Study 多孔CoNiCrFeMn高熵合金界面磨损的原子尺度研究

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-01 DOI: 10.1021/acs.langmuir.5c06190

Shaocong Zhou, Yongchao Liang, Yuanwei Pu, Yu Zhou, Xiuzhen Tang, Lili Zhou, Qian Chen, Zean Tian, Tinghong Gao

Pores are common processing defects, yet their effects on the mechanical and tribological properties of high-entropy alloys (HEAs) remain unclear. In this study, molecular dynamics simulations were conducted to systematically explore the influence of pore size on mechanical behavior and deformation mechanisms of a single-crystal FCC CoNiCrFeMn HEA during nanoindentation and scratch processes. Introducing pores leads to a noticeable decrease in hardness and a rise in potential energy, ultimately promoting greater deformability. During scratch, porous models exhibit lower friction forces and fewer wear atoms, exhibiting beneficial wear reduction properties. Compared to dense counterparts, porous structures induce localized shear concentrations around pores. Larger pores offer more space for accommodating plastic deformation and are correlated with a reduced dislocation density near the contact region. Furthermore, pores act as efficient dislocation barriers, restricting their propagation within the alloy matrix. By varying the simulation temperature and scratch speed, we further analyze their effects on deformation behavior in porous HEAs. Elevated temperatures intensify atomic rearrangements, causing pronounced material softening and reduced dislocation density. Conversely, higher scratch speeds increase frictional force and indentation load and weaken crystal plasticity.

孔隙是高熵合金中常见的加工缺陷，但其对高熵合金力学性能和摩擦学性能的影响尚不清楚。本研究通过分子动力学模拟，系统探讨了孔径对单晶FCC CoNiCrFeMn HEA在纳米压痕和划痕过程中力学行为和变形机制的影响。孔隙的引入导致硬度的显著降低和势能的上升，最终促进更大的变形能力。在划伤过程中，多孔模型表现出更低的摩擦力和更少的磨损原子，表现出有利于减少磨损的性能。与致密结构相比，多孔结构在孔隙周围引起局部剪切集中。较大的孔隙为容纳塑性变形提供了更多的空间，并且与接触区域附近的位错密度降低有关。此外，孔隙作为有效的位错屏障，限制了它们在合金基体中的扩展。通过改变模拟温度和划痕速度，我们进一步分析了它们对多孔HEAs变形行为的影响。升高的温度加剧原子重排，造成明显的材料软化和位错密度降低。相反，较高的划痕速度会增加摩擦力和压痕负荷，削弱晶体塑性。

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引用次数: 0

Aptamer-Functionalized CuNPs for Label-Free and Highly-Sensitive Detection of Interleukin-6 Using a Light-Addressable Potentiometric Sensor 利用光可寻址电位传感器进行无标记和高灵敏度白介素-6检测的适配体功能化CuNPs

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Langmuir

Pub Date : 2026-02-01 DOI: 10.1021/acs.langmuir.5c05621

Beenish Noureen,Miaomiao Wang,Yating Chen,Wei Chen,Liping Du,Chunsheng Wu

Interleukin-6 (IL-6) is a crucial biomarker for monitoring inflammatory responses and chronic diseases, including cancer. In this work, we present a novel label-free aptasensor that combines copper nanoparticles (CuNPs) with a light-addressable potentiometric sensor (LAPS) platform, enabling the highly-sensitive detection of IL-6. The presence of CuNPs significantly enhances electron transfer dynamics and potentiometric signal amplification, while IL-6-specific Aptamers offer high molecular recognition and binding affinity. The sensor transduces IL-6 binding events into detectable potential shifts, enabling quantitative analysis. The device exhibited exceptional selectivity in the presence of potential interfering substances, maintained high stability over multiple measurement cycles, and showed strong reproducibility. Under optimized parameters, the sensor achieved a wide linear detection range from 5 to 200 ng/mL, with a remarkably low detection limit of 2.1 pg/mL. Additionally, its successful performance in spiked human serum samples highlights its practicality and robustness for clinical diagnostic applications.

白细胞介素-6 （IL-6）是监测炎症反应和包括癌症在内的慢性疾病的重要生物标志物。在这项工作中，我们提出了一种新型的无标记适配体传感器，它将铜纳米粒子（CuNPs）与光寻址电位传感器（LAPS）平台结合在一起，实现了对IL-6的高灵敏度检测。CuNPs的存在显著增强了电子传递动力学和电位信号放大，而il -6特异性适配体具有较高的分子识别和结合亲和力。传感器将IL-6结合事件转换为可检测的电位变化，从而实现定量分析。该装置在潜在干扰物质存在下表现出优异的选择性，在多个测量周期内保持高稳定性，并表现出很强的重现性。在优化后的参数下，传感器的线性检测范围为5 ~ 200 ng/mL，检出限极低，仅为2.1 pg/mL。此外，其在加标人血清样品中的成功表现突出了其在临床诊断应用中的实用性和稳健性。

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引用次数: 0