Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00002.3
Smita Singh, N. Mishra, Shraddha Singh, SunitaTiwari
Background: Guillain-Barre Syndrome (GBS) is an acute, frequently severe and fulminant polyradicular neuropathy that is autoimmune in nature. GBS manifest as rapidly evolving areflexic motor paralysis with or without sensory disturbances. It mainly involves peripheral nervous system and autonomic nervous system. There are rare evidences about the involvement of central nervous system (CNS) in GBS. Aims: The main objective of the study was to assess the CNS involvement in GBS using the Brainstem Auditory Evoked Potential (BAEP). Methods & Material: The study was conducted in the clinical neurophysiology lab in the department of physiology, CSMMU Lucknow. Study group involved 26 subjects (n=26) having GBS and control group involved 30 normal subjects (n=30). BAEPS were recorded by Neuroperfect- EMG 2000 EMG/NCV/EPsytem. The data so obtained were subjected to analysis using Statistical Package for Social Sciences (SPSS) Version 13.0. Results & Conclusions: There was significant increase in PIII & PV peak latencies and PI-PIII & PI-PV interpeak latencies in both left and right ear in the study group, which showed the CNS involvement in GBS which can be assessed using BAEP.
{"title":"Brainstem auditory evoked potential as an index of CNS demyelination in Guillain-Barré Syndrome (GBS)","authors":"Smita Singh, N. Mishra, Shraddha Singh, SunitaTiwari","doi":"10.5958/2319-5886.2016.00002.3","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00002.3","url":null,"abstract":"Background: Guillain-Barre Syndrome (GBS) is an acute, frequently severe and fulminant polyradicular neuropathy that is autoimmune in nature. GBS manifest as rapidly evolving areflexic motor paralysis with or without sensory disturbances. It mainly involves peripheral nervous system and autonomic nervous system. There are rare evidences about the involvement of central nervous system (CNS) in GBS. Aims: The main objective of the study was to assess the CNS involvement in GBS using the Brainstem Auditory Evoked Potential (BAEP). Methods & Material: The study was conducted in the clinical neurophysiology lab in the department of physiology, CSMMU Lucknow. Study group involved 26 subjects (n=26) having GBS and control group involved 30 normal subjects (n=30). BAEPS were recorded by Neuroperfect- EMG 2000 EMG/NCV/EPsytem. The data so obtained were subjected to analysis using Statistical Package for Social Sciences (SPSS) Version 13.0. Results & Conclusions: There was significant increase in PIII & PV peak latencies and PI-PIII & PI-PV interpeak latencies in both left and right ear in the study group, which showed the CNS involvement in GBS which can be assessed using BAEP.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71079665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00004.7
Riddhi Shroff, Vrushali P. Panhale
Background & Purpose - Anterior knee pain is one of the most common musculoskeletal complain seen in Indian adolescent population with high incidence among those who are active in sports and recreation. The purpose of this study was to investigate the age of onset of anterior knee pain, to find its effect on sports participation and also to find the activities which are maximally affected due to anterior knee pain in Indian population. Method- A questionnaire based survey was conducted among 50 subjects using three outcome measures namely self made demographic questionnaire, anterior knee pain scale and lower extremity functional scale. Result- Maximally affected activities are running, jumping & squatting and maximally affected functions are squatting, running on uneven ground, making sharp turns while running and hopping with increase incidence of anterior knee pain among those who participate daily in sports. Conclusion- The study concluded, that in adolescent age group of 11-17 years, anterior knee pain is more prevalent in adolescent girls with the age of onset being around 13 years for girls & 14.5 years in boys and it also showed moderate positive correlation between anterior knee pain and lower extremity functions
{"title":"ANTERIOR KNEE PAIN AND LOWER EXTREMITY FUNCTIONS IN INDIAN ADOLESCENT POPULATION","authors":"Riddhi Shroff, Vrushali P. Panhale","doi":"10.5958/2319-5886.2016.00004.7","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00004.7","url":null,"abstract":"Background & Purpose - Anterior knee pain is one of the most common musculoskeletal complain seen in Indian adolescent population with high incidence among those who are active in sports and recreation. The purpose of this study was to investigate the age of onset of anterior knee pain, to find its effect on sports participation and also to find the activities which are maximally affected due to anterior knee pain in Indian population. Method- A questionnaire based survey was conducted among 50 subjects using three outcome measures namely self made demographic questionnaire, anterior knee pain scale and lower extremity functional scale. Result- Maximally affected activities are running, jumping & squatting and maximally affected functions are squatting, running on uneven ground, making sharp turns while running and hopping with increase incidence of anterior knee pain among those who participate daily in sports. Conclusion- The study concluded, that in adolescent age group of 11-17 years, anterior knee pain is more prevalent in adolescent girls with the age of onset being around 13 years for girls & 14.5 years in boys and it also showed moderate positive correlation between anterior knee pain and lower extremity functions","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71079684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00014.x
Pankaj Kumar, D. Sg, M. Jha
Introduction: Intravenous regional anaesthesia (IVRA) or Bier’s block is easy to administer, reliable, and cost-effective for short operative procedures of the extremities performed on an ambulatory basis where a local anaesthetic is injected intravenously using tourniquet. Objectives: To compare the effectiveness of i.v paracetamol as add on therapy to lidocaine in Intravenous Regional Anaesthesia with those receiving plain Lidocaine .Methodology:66 patients were randomly and blindly divided into 3 groups. All groups received IVRA lidocaine (3 mg/kg) diluted with saline to a total volume of 40 mL. Group 1 - lidocaine plus IV saline, Group - lidocaine and paracetamol (300 mg) admixture plus IV saline, and Group 3 - lidocaine plus IV paracetamol (300 mg).Sensory and motor block onset time, tourniquet pain, and analgesic use were assessed during operation. Visual analog scale (VAS) scores was used to assess pain. Results: Onset of motor block was shorter and recovery of motor and sensory block was significantly longer in Group 2 (P < 0.05). VAS scores were significantly lower in Group 2 (P < 0.05).Preoperative and postoperative analgesic consumption was significantly less in Group 2 (P <0.05). Conclusion: The addition of paracetamol during IVRA with lidocaine decreased tourniquet pain, increased anaesthesia quality, and decreased postoperative analgesic consumption.
{"title":"Analgesic efficacy of paracetamol when used as adjuvant in IVRA","authors":"Pankaj Kumar, D. Sg, M. Jha","doi":"10.5958/2319-5886.2016.00014.x","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00014.x","url":null,"abstract":"Introduction: Intravenous regional anaesthesia (IVRA) or Bier’s block is easy to administer, reliable, and cost-effective for short operative procedures of the extremities performed on an ambulatory basis where a local anaesthetic is injected intravenously using tourniquet. Objectives: To compare the effectiveness of i.v paracetamol as add on therapy to lidocaine in Intravenous Regional Anaesthesia with those receiving plain Lidocaine .Methodology:66 patients were randomly and blindly divided into 3 groups. All groups received IVRA lidocaine (3 mg/kg) diluted with saline to a total volume of 40 mL. Group 1 - lidocaine plus IV saline, Group - lidocaine and paracetamol (300 mg) admixture plus IV saline, and Group 3 - lidocaine plus IV paracetamol (300 mg).Sensory and motor block onset time, tourniquet pain, and analgesic use were assessed during operation. Visual analog scale (VAS) scores was used to assess pain. Results: Onset of motor block was shorter and recovery of motor and sensory block was significantly longer in Group 2 (P < 0.05). VAS scores were significantly lower in Group 2 (P < 0.05).Preoperative and postoperative analgesic consumption was significantly less in Group 2 (P <0.05). Conclusion: The addition of paracetamol during IVRA with lidocaine decreased tourniquet pain, increased anaesthesia quality, and decreased postoperative analgesic consumption.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00019.9
Bandana Chatterjee, K. Modi, T. Patel
Now-a-days people consumption habits are changing they are inclined to buy healthy food that fulfills the need of essential nutrients in the body. With increasing educational level, people are becoming ready to accept different types of food & beverages that have added nutritional ingredient. Hence with this change, nutraceutical ingredient is gaining importance. Nutraceutical are those that combine technological and health properties. Nutraceutical Ingredients are substances with clinically confirmed health benefits and have broad applications in foods, beverages, dietary supplements and nutritional preparations. There are huge numbers of ingredients which are still unexplored. They have still not gained popularity in food industry. In this review paper a brief introduction of nutraceutical ingredient, its market and detailed knowledge of- Ginseng, Pine Bark Extract, Seabuckthorn, Buckwheat is mentioned
{"title":"FOOD AS VECTOR FOR NUTRACEUTICAL INGREDIENTS","authors":"Bandana Chatterjee, K. Modi, T. Patel","doi":"10.5958/2319-5886.2016.00019.9","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00019.9","url":null,"abstract":"Now-a-days people consumption habits are changing they are inclined to buy healthy food that fulfills the need of essential nutrients in the body. With increasing educational level, people are becoming ready to accept different types of food & beverages that have added nutritional ingredient. Hence with this change, nutraceutical ingredient is gaining importance. Nutraceutical are those that combine technological and health properties. Nutraceutical Ingredients are substances with clinically confirmed health benefits and have broad applications in foods, beverages, dietary supplements and nutritional preparations. There are huge numbers of ingredients which are still unexplored. They have still not gained popularity in food industry. In this review paper a brief introduction of nutraceutical ingredient, its market and detailed knowledge of- Ginseng, Pine Bark Extract, Seabuckthorn, Buckwheat is mentioned","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00020.5
Rajalakshmi., Rajkishori, S. R. Devi, Pritam Singh, T. Kom
Primary cervical pregnancy is a rare entity, the reported incidence being 1 in 8,600 to 12,400 and 1% of extrauterine pregnancies. A case of maternal near miss with cervical pregnancy in 29 yr old gravida three para two with previous caesarean section presented with bleeding per vagina followed by 16 weeks of amenorrhoea with severe pallor and features of hypovolaemic shock is described. Urine beta HCG test was positive. She was resuscitated and underwent laparotomy followed by total abdominal hysterectomy with bilateral ovaries preserved. Histopathological examination confirmed the diagnosis with features of endocervical trophoblastic invasion. A literature review discloses very few cases of cervical pregnancy. Early detection and prompt treatment can preserve the future fertility of the woman.
{"title":"CERVICAL ECTOPIC PREGNANCY - A MATERNAL NEAR MISS CASE","authors":"Rajalakshmi., Rajkishori, S. R. Devi, Pritam Singh, T. Kom","doi":"10.5958/2319-5886.2016.00020.5","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00020.5","url":null,"abstract":"Primary cervical pregnancy is a rare entity, the reported incidence being 1 in 8,600 to 12,400 and 1% of extrauterine pregnancies. A case of maternal near miss with cervical pregnancy in 29 yr old gravida three para two with previous caesarean section presented with bleeding per vagina followed by 16 weeks of amenorrhoea with severe pallor and features of hypovolaemic shock is described. Urine beta HCG test was positive. She was resuscitated and underwent laparotomy followed by total abdominal hysterectomy with bilateral ovaries preserved. Histopathological examination confirmed the diagnosis with features of endocervical trophoblastic invasion. A literature review discloses very few cases of cervical pregnancy. Early detection and prompt treatment can preserve the future fertility of the woman.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00021.7
D. A. M. Kheiralla
Invasive thymomas are rare tumours in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumours. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumours is Thymectomy. This case study presents a 49 year-old man with unusual presentation of thymoma. On the non-contrast CT images, there was a welldefined heterogeneous anterior mediastinal mass adjacent to the right border of the heart. There was evidence of infiltrations into the anterior mediastinal fat but no mediastinal lymphadenopathy after contrast enhancement, the mass showed heterogeneous enhancement. CT guided trucut tissue biopsy and histological analysis of the mass showed that the tumour consists of neoplastic epithelial cells and non-neoplastic lymphocytes. The findings were consistent with invasive lymphoepithelial thymoma.
{"title":"CASE REPORT OF UNUSUAL PRESENTATION OF INVASIVE THYMOMA IN A 49 YEARS OLD MALE","authors":"D. A. M. Kheiralla","doi":"10.5958/2319-5886.2016.00021.7","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00021.7","url":null,"abstract":"Invasive thymomas are rare tumours in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumours. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumours is Thymectomy. This case study presents a 49 year-old man with unusual presentation of thymoma. On the non-contrast CT images, there was a welldefined heterogeneous anterior mediastinal mass adjacent to the right border of the heart. There was evidence of infiltrations into the anterior mediastinal fat but no mediastinal lymphadenopathy after contrast enhancement, the mass showed heterogeneous enhancement. CT guided trucut tissue biopsy and histological analysis of the mass showed that the tumour consists of neoplastic epithelial cells and non-neoplastic lymphocytes. The findings were consistent with invasive lymphoepithelial thymoma.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00003.5
Kazuya Ikenishi, J. Matsuura
Introduction: Ambulance use was increasing along with growth population of aged in Japan. The purpose of study paper is to clarify the relationship between the state of healthcare service use as well as regional characteristics and ambulance use on regions. The regions that were focused on in this study were 16 wards in Nagoya city, and those data for the past 10 years was analyzed. Methods: Analyzed variables in this study were those in previous studies reported had statistical significant with the number of ambulance use, as well as dummy variables represented year. These variables involved population and the number of household, the proportion of population aged 65 or over, the population of foreigners, proportion of livelihood protection recipients, regional health promotion measures, the proportion of health-checkups user, the number of retained motor vehicles. Spearman's rank correlation coefficient and multiple regression analysis were used. Results: This study included 160 data on 16wards in Nagoya city from 2004 to 2013. Results of multiple regression analysis showed that 6 variables were statistically significant: the number of households, population of foreigners, proportion of livelihood protection recipients, Colon cancer examinee rate, the number of participants in regional health promotion measures, the number of beds per 100,000 populations. Conclusion: This study founded that the variables related with the number of ambulance user were the number of households, population of foreigners, proportion of livelihood protection recipients, Colon cancer examinee rate, the number of participants in regional health promotion measures, number of beds per 100,000 populations.
{"title":"REGIONAL FACTORS RELATED WITH THE NUMBER OF AMBULANCE USERS","authors":"Kazuya Ikenishi, J. Matsuura","doi":"10.5958/2319-5886.2016.00003.5","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00003.5","url":null,"abstract":"Introduction: Ambulance use was increasing along with growth population of aged in Japan. The purpose of study paper is to clarify the relationship between the state of healthcare service use as well as regional characteristics and ambulance use on regions. The regions that were focused on in this study were 16 wards in Nagoya city, and those data for the past 10 years was analyzed. Methods: Analyzed variables in this study were those in previous studies reported had statistical significant with the number of ambulance use, as well as dummy variables represented year. These variables involved population and the number of household, the proportion of population aged 65 or over, the population of foreigners, proportion of livelihood protection recipients, regional health promotion measures, the proportion of health-checkups user, the number of retained motor vehicles. Spearman's rank correlation coefficient and multiple regression analysis were used. Results: This study included 160 data on 16wards in Nagoya city from 2004 to 2013. Results of multiple regression analysis showed that 6 variables were statistically significant: the number of households, population of foreigners, proportion of livelihood protection recipients, Colon cancer examinee rate, the number of participants in regional health promotion measures, the number of beds per 100,000 populations. Conclusion: This study founded that the variables related with the number of ambulance user were the number of households, population of foreigners, proportion of livelihood protection recipients, Colon cancer examinee rate, the number of participants in regional health promotion measures, number of beds per 100,000 populations.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71079676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00007.2
A. A. Sharif, Muhammad Ibrahim Getso, Yusuf, I. Yusuf, I. Muhd, I. Ahmad
Introduction: Malaria and Hepatitis B Virus (HBV) co-infections present major threat to public health throughout tropical and Sub-Saharan Africa. This study was carried out to analyze the status of liver enzymes and serum protein in HBV and malaria co-infected patients in Murtala Muhammed Specialist Hospital (MMSH) Kano. Methods: Standard microscopy and rapid diagnostic test (RDT) were used separately to screen for mono and co-infections among 200 outpatients presented with fever. Their serum protein and liver enzymes were investigated. Results: Among the total subjects studied 25.5% were malaria positive. Females had higher rate of malaria infection (18%) than males (7.5%). Age group 15-24 had the highest malaria prevalence (11%). Thirteen (6.5%) subjects were HBV positive. Males had higher rate of infection (4.5%) than females (2.0%). Male subjects had higher prevalence of co-infection representing 4.5% and age groups 25-34 were observed to have highest co-infection rate of 1.5%. Biochemical parameters analyzed on all the categories of subjects shows significant difference in their mean values as compared to other groups (P<0.05). However no significant difference was observed in the value of ALP in all the groups. Statistical difference was also established in ALB values between the co-infection and malaria groups (P=0.037) and between malaria and control group (P=0.022). There is also a statistical difference in the mean value of total bilirubin among the groups P<0.05 and mean value of DB between HBV and control groups (P=0.022). Conclusion: The study showed that co-infection of malaria and HBV infection had no profound effect on the level of serum protein and liver enzyme activities in the serum.
{"title":"LIVER FUNCTION BIOMARKERS IN MALARIA AND HEPATITIS B CO-INFECTION AMONG PATIENTS WITH FEBRILE ILLNESS","authors":"A. A. Sharif, Muhammad Ibrahim Getso, Yusuf, I. Yusuf, I. Muhd, I. Ahmad","doi":"10.5958/2319-5886.2016.00007.2","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00007.2","url":null,"abstract":"Introduction: Malaria and Hepatitis B Virus (HBV) co-infections present major threat to public health throughout tropical and Sub-Saharan Africa. This study was carried out to analyze the status of liver enzymes and serum protein in HBV and malaria co-infected patients in Murtala Muhammed Specialist Hospital (MMSH) Kano. Methods: Standard microscopy and rapid diagnostic test (RDT) were used separately to screen for mono and co-infections among 200 outpatients presented with fever. Their serum protein and liver enzymes were investigated. Results: Among the total subjects studied 25.5% were malaria positive. Females had higher rate of malaria infection (18%) than males (7.5%). Age group 15-24 had the highest malaria prevalence (11%). Thirteen (6.5%) subjects were HBV positive. Males had higher rate of infection (4.5%) than females (2.0%). Male subjects had higher prevalence of co-infection representing 4.5% and age groups 25-34 were observed to have highest co-infection rate of 1.5%. Biochemical parameters analyzed on all the categories of subjects shows significant difference in their mean values as compared to other groups (P<0.05). However no significant difference was observed in the value of ALP in all the groups. Statistical difference was also established in ALB values between the co-infection and malaria groups (P=0.037) and between malaria and control group (P=0.022). There is also a statistical difference in the mean value of total bilirubin among the groups P<0.05 and mean value of DB between HBV and control groups (P=0.022). Conclusion: The study showed that co-infection of malaria and HBV infection had no profound effect on the level of serum protein and liver enzyme activities in the serum.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71079807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00017.5
Pravinkumar A Wahane, R. Jagtap, B. Ghongane
Background: Skin diseases account for 2% of the Out Patient Department based consultations in general practice worldwide, which includes diseases like, Dermatitis, Eczema, Acne, Urticaria, Psoriasis, skin allergy etc. Corticosteroids are one of the most commonly prescribed drugs in the skin diseases. Collection of data on the utilization of drugs at the hospital outpatient level has been shown to be an effective tool to constitute guidelines for improving utilization patterns. Objectives: Present study was designed to study utilization pattern of corticosteroid drugs with special emphasis on their adverse effects in a tertiary care teaching hospital. Materials and Methods: Prescriptions from department of dermatology were evaluated to know current trends. Results: Out of total 756 patients, 56.34% were male and 43.65 % were females. Corticosteroids were most commonly prescribed for Eczema (27.38%). 28.43 % of the drugs were prescribed from WHO essential drugs list. Corticosteroids were most commonly prescribed by topical route (86.48%). Diagnosis was included in 92.72 % of the prescriptions, while strength of the topical corticosteroidal was mentioned in 84.78 % of the prescriptions. Strength of the topical corticosteroidal was mentioned in 84.78 % of prescriptions. High potency topical corticosteroids were prescribed most frequently (63.72%). Total 32 steroid related adverse drug reactions were reported, Prednisolone was most commonly associated with adverse drug reactions. Conclusions: Present study reports use of High potency corticosteroids more frequently than others and emphasizes need of rational and complete prescribing of steroids in dermatology
{"title":"EVALUATION OF CORTICOSTEROID USE PATTERN IN STEROID RESPONSIVE DERMATOLOGICAL CONDITIONS","authors":"Pravinkumar A Wahane, R. Jagtap, B. Ghongane","doi":"10.5958/2319-5886.2016.00017.5","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00017.5","url":null,"abstract":"Background: Skin diseases account for 2% of the Out Patient Department based consultations in general practice worldwide, which includes diseases like, Dermatitis, Eczema, Acne, Urticaria, Psoriasis, skin allergy etc. Corticosteroids are one of the most commonly prescribed drugs in the skin diseases. Collection of data on the utilization of drugs at the hospital outpatient level has been shown to be an effective tool to constitute guidelines for improving utilization patterns. Objectives: Present study was designed to study utilization pattern of corticosteroid drugs with special emphasis on their adverse effects in a tertiary care teaching hospital. Materials and Methods: Prescriptions from department of dermatology were evaluated to know current trends. Results: Out of total 756 patients, 56.34% were male and 43.65 % were females. Corticosteroids were most commonly prescribed for Eczema (27.38%). 28.43 % of the drugs were prescribed from WHO essential drugs list. Corticosteroids were most commonly prescribed by topical route (86.48%). Diagnosis was included in 92.72 % of the prescriptions, while strength of the topical corticosteroidal was mentioned in 84.78 % of the prescriptions. Strength of the topical corticosteroidal was mentioned in 84.78 % of prescriptions. High potency topical corticosteroids were prescribed most frequently (63.72%). Total 32 steroid related adverse drug reactions were reported, Prednisolone was most commonly associated with adverse drug reactions. Conclusions: Present study reports use of High potency corticosteroids more frequently than others and emphasizes need of rational and complete prescribing of steroids in dermatology","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-01DOI: 10.5958/2319-5886.2016.00022.9
Pradipprava Paria, P. Mondal, Sibnath Gayen, G. Ch, R. Das
Harlequin ichthyosis is the most severe form of congenital ichthyosis. It is a rare autosomal recessive disorder (1: 300, 000). The vast majority of affected individuals are due to mutation in the ABCA12 gene, which cause a deficiency of the epidermal lipid transporter, resulting in hyperkeratosis and abnormal barrier function of skin. Infants are very susceptible to metabolic abnormalities and infections. They usually do not survive for very long. We report here a case of a newborn with harlequin ichthyosis of consanguineous parentage who had a history of similar birth previously.
{"title":"HARLEQUIN ICTHYOSIS: A RARE CASE REPORT","authors":"Pradipprava Paria, P. Mondal, Sibnath Gayen, G. Ch, R. Das","doi":"10.5958/2319-5886.2016.00022.9","DOIUrl":"https://doi.org/10.5958/2319-5886.2016.00022.9","url":null,"abstract":"Harlequin ichthyosis is the most severe form of congenital ichthyosis. It is a rare autosomal recessive disorder (1: 300, 000). The vast majority of affected individuals are due to mutation in the ABCA12 gene, which cause a deficiency of the epidermal lipid transporter, resulting in hyperkeratosis and abnormal barrier function of skin. Infants are very susceptible to metabolic abnormalities and infections. They usually do not survive for very long. We report here a case of a newborn with harlequin ichthyosis of consanguineous parentage who had a history of similar birth previously.","PeriodicalId":51699,"journal":{"name":"International Journal of Medical Research & Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71080307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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