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Screening of camphene as a potential inhibitor targeting SARS-CoV-2 various structural and functional mutants: Through reverse docking approach camphene作为靶向严重急性呼吸系统综合征冠状病毒2型各种结构和功能突变体的潜在抑制剂的筛选:通过反向对接方法
IF 1.6 Q2 Environmental Science Pub Date : 2023-05-27 DOI: 10.34172/ehem.2023.14
Mahendra Kumar Savita, N. Bora, Ruby Singh, P. Srivastava
Background: SARS-CoV was first identified in 2003 but SARS-CoV-2, which gained its recognition again in 2019 as COVID-19, has been a crucial threat worldwide and has caused more death rates than the SARS-CoV but till now no confined treatments are available. The present study aimed to investigate the efficacy of camphene against various structural and functional mutants of SARS-CoV-2 using reverse docking protocol. Methods: To investigate the efficacy of camphene as a potential antiviral drug against COVID-19, against of all possible target proteins in SARS-CoV-2, which could lead to a new platform for drug discovery. Reverse pharmacology (Reverse docking) approach was performed, which involved docking of camphene and 20 structural and non-structural proteins (NSPs) of SARS-CoV-2 performed using maestro 12.8 of Schrödinger. Results: The results were evaluated since the minimum binding energy obtained after docking and camphene was effective against most of the proteins responsible for SARS-CoV-2, but camphene showed greater efficacy against the main protease (protease 9), which is main functional protein of SARS-CoV-2. Hence, the study proves that camphene can be a good drug candidate for different mutants of SARS-CoV-2. Conclusion: Protease 9, which is the main functional protein of SARS-CoV-2, expressed the best binding affinity with camphene having the minimum binding energy (-5.616). Hence, it is concluded that camphene could be the drug contender against protease 9 as it is a more potent target in SARS-CoV-2. This could be a major finding, as camphene is related to camphor, which is already very beneficial against many respiratory problems.
背景:SARS-CoV于2003年首次被发现,但在2019年再次被确认为新冠肺炎的SARS-CoV-2在全球范围内一直是一个关键威胁,导致的死亡率高于SARS-CoV,但到目前为止还没有有限的治疗方法。本研究旨在使用反向对接方案研究camphene对严重急性呼吸系统综合征冠状病毒2型各种结构和功能突变体的疗效。方法:研究camphene作为一种潜在的抗病毒药物对抗新冠肺炎的疗效,对抗SARS-CoV-2中所有可能的靶蛋白,这可能为药物发现提供一个新的平台。进行了反向药理学(反向对接)方法,包括使用薛定谔的大师12.8对camphene和20种严重急性呼吸系统综合征冠状病毒2型的结构和非结构蛋白(NSPs)进行对接。结果:对结果进行了评估,因为对接后获得的最小结合能和樟脑对大多数导致严重急性呼吸系统综合征冠状病毒2型的蛋白质有效,但樟脑对主要蛋白酶(蛋白酶9)显示出更大的效力,蛋白酶9是严重急性呼吸系统冠状病毒2号的主要功能蛋白。因此,该研究证明,camphene可以作为治疗严重急性呼吸系统综合征冠状病毒2型不同突变体的良好候选药物。结论:蛋白酶9是严重急性呼吸系统综合征冠状病毒2型的主要功能蛋白,与camphene的结合亲和力最高,结合能最低(-5.616)。这可能是一个重大发现,因为樟脑与樟脑有关,樟脑已经对许多呼吸系统问题非常有益。
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引用次数: 0
A survey on air pollutant PM2.5 prediction using random forest model 基于随机森林模型的大气污染物PM2.5预测研究
IF 1.6 Q2 Environmental Science Pub Date : 2023-05-25 DOI: 10.34172/ehem.2023.18
S. Babu, B. Thomas
Background: One of the most critical contributors to air pollution is particulate matter (PM2.5) that its acute or chronic exposure causes serious health effects to human. Accurate forecasting of PM2.5 concentration is essential for air pollution control and prevention of health complications. A survey of the available scientific literature on random forest model for PM2.5 prediction is presented here. Methods: The scientific literature is extracted from Science Direct database based on a set of specified search criteria. The input features, data length, and evaluation parameters used in PM2.5 prediction were analyzed in this study. Results: The study shows that majority of the publications are aimed at the daily prediction of outdoor PM2.5. Most publications base their PM2.5 prediction on features aerosol optical depth (AOD) and boundary layer height (BLH). PM10 and NO2 are the main air pollutants employed in the PM2.5 estimation. Majority studies utilized input data lengths covering more than one year, and the effectiveness of prediction models are unaffected by the length of investigation. The coefficient of determination, R2 , is the primary evaluation parameter used in all publications. The majority of research study indicated R2 values greater than 0.85, demonstrating the reasonable dependability and efficiency of random forest regression-based PM2.5 prediction models. Conclusion: The study demonstrates that the publications use a variety of meteorological and geological features for PM2.5 estimation, depending on the context of the research as well as data accessibility. The findings demonstrate that it is hard to pinpoint the optimal model in any particular way.
背景:造成空气污染的最关键因素之一是颗粒物(PM2.5),其急性或慢性暴露会对人类健康造成严重影响。准确预测PM2.5浓度对于控制空气污染和预防健康并发症至关重要。本文对用于PM2.5预测的随机森林模型的现有科学文献进行了调查。方法:根据一组指定的搜索标准,从Science Direct数据库中提取科学文献。本研究分析了PM2.5预测中使用的输入特征、数据长度和评估参数。结果:研究表明,大多数出版物都是针对户外PM2.5的日常预测。大多数出版物的PM2.5预测是基于气溶胶光学深度(AOD)和边界层高度(BLH)的特征。PM10和NO2是PM2.5估算中使用的主要空气污染物。大多数研究使用的输入数据长度超过一年,预测模型的有效性不受调查长度的影响。决定系数R2是所有出版物中使用的主要评估参数。大多数研究表明R2值大于0.85,证明了基于随机森林回归的PM2.5预测模型的合理可靠性和有效性。结论:研究表明,根据研究背景和数据可及性,出版物使用了各种气象和地质特征来估计PM2.5。研究结果表明,很难以任何特定的方式精确定位最优模型。
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引用次数: 1
The use of a pumice stone in removal of petroleum hydrocarbons from industrial wastewater through coagulation and flocculation 浮石在混凝絮凝法去除工业废水中石油烃的应用
IF 1.6 Q2 Environmental Science Pub Date : 2023-05-12 DOI: 10.34172/ehem.2023.16
Haider Kamel Alzaidy, Firas Mustafa Al Khatib, A. Dawood
Background: Petroleum hydrocarbons that are released from industrial processes cause damage to aquatic life and degrade ecosystems by accumulating in the food chain, allowing living organisms to produce toxic secretions. Methods: In this study, a pumice stone was used to remove total petroleum hydrocarbons (TPHs) from industrial wastewater in the south refinery company in Iraq/Basrah by coagulation and flocculation processes using the design of experiments (DOE) approach using the method of analyzing screening designs and measurement of the samples using GC instrument. Results: The maximum removal was 99% at pH 3, coagulation dose of 0.5 g, and time of 60 min, and a comparison was made between the DOE and the multiple linear regression (MLR) to determine the effectiveness of the system used, which proved its incredible effectiveness. Conclusion: According to the results, a great convergence between the actual and prediction results of removal was found, while MLR was very far from the actual and predicted removal results. The high efficiency of pumice stone was found in removing petroleum hydrocarbons from the industrial wastewater of the South Refineries Company. Pumice stone is widely available in the market and cheap economically.
背景:工业过程中释放的石油碳氢化合物在食物链中积累,使生物体产生有毒分泌物,从而对水生生物造成损害,并使生态系统退化。方法:在本研究中,使用浮石通过混凝和絮凝工艺去除伊拉克/巴士拉南炼油公司工业废水中的总石油烃(TPHs),采用实验设计(DOE)方法,采用GC仪器分析筛选设计和测量样品的方法。结果:在pH为3、凝血剂量为0.5g、时间为60min时,最大去除率为99%,并将DOE和多元线性回归(MLR)进行了比较,以确定所用系统的有效性,这证明了其令人难以置信的有效性。结论:根据结果,去除的实际结果和预测结果之间有很大的收敛性,而MLR与实际和预测的去除结果相差甚远。利用浮石对南方炼油厂工业废水中的石油烃进行了高效去除。浮石在市场上很普遍,而且价格便宜。
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引用次数: 0
Development of a software tool for economic evaluation of health, safety, and environmental initiatives in a combined cycle power plant 开发用于联合循环发电厂健康、安全和环境倡议经济评估的软件工具
IF 1.6 Q2 Environmental Science Pub Date : 2023-05-04 DOI: 10.34172/ehem.2023.22
Dr. H. Miri, R. Gholamnia, A. Bagheri, R. Saeedi
Background: This study aimed to provide a comprehensive tool for the economic evaluation of investments in health, safety, and environment (HSE). Methods: This developmental cross-sectional study was conducted on the costs and benefits of HSE investments in a combined cycle power plant in Gilan province, 2021. The components of preventive measure costs (PMCs) and occupational accidents, diseases, and environmental pollution costs (ADPCs) were determined by an expert panel and review of scientific literature. The HSE economic assessment tool (HSE-EAT) was developed in Microsoft Excel software using macro/visual basic coding. The tool was designed to determine the efficient measures using the cost-benefit analysis (CBA) and the combination of control measures with the highest financial benefits using the cost-effectiveness analysis (CEA). Results: The application of the HSE-EAT in a combined cycle power plant showed the highest return on investment (ROI) for installation of drains for ducts of diesel fuel pipes and the lowest ROI value for renovation of emergency eyewash and shower. The ratio of indirect to direct benefits of implementing the preventive measures in the worst-case and best-case scenarios were 3.0 and 1.3, respectively. Conclusion: The HSE-EAT exhibited the advantages of comprehensiveness, flexibility, being user-friendly, and faster and more accurate calculations and could be also used for economic evaluation of health, safety and environmental initiatives in other industries and organizations.
背景:本研究旨在为健康、安全和环境(HSE)投资的经济评估提供一个全面的工具。方法:对2021年吉兰省一家联合循环电厂的HSE投资成本和收益进行了发展横断面研究。预防措施成本(PMCs)和职业事故、疾病和环境污染成本(ADPCs)的组成部分由一个专家小组和科学文献的审查确定。HSE经济评价工具(HSE- eat)在Microsoft Excel软件中使用宏/visual basic编码开发。该工具旨在使用成本效益分析(CBA)确定有效措施,并使用成本效益分析(CEA)结合具有最高经济效益的控制措施。结果:在某联合循环电厂中应用HSE-EAT的投资回报率最高的是柴油管道排水管的安装,投资回报率最低的是应急洗眼器和淋浴器的改造。在最坏情况和最佳情况下,实施预防措施的间接效益与直接效益之比分别为3.0和1.3。结论:HSE-EAT具有全面、灵活、操作方便、计算速度快、准确等优点,可用于其他行业和组织的健康、安全和环境经济评价。
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引用次数: 0
Activation of persulfate by TiO2 -Fe3 O4 nanocomposite for reactive red 198 degradation along with modeling and optimization approach TiO2 -Fe3 O4纳米复合材料活化过硫酸盐降解活性红198及建模与优化方法
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-25 DOI: 10.34172/ehem.2023.19
S. Rahimi, F. Mohammadi, Soudabeh Ghodsi, Maryam Mohammadi, H. Karimi
Background: Recently, sulfate radical-based photocatalytic processes have attracted significant interests because of unique advantages in pollutants purification. In this study, TiO2 -Fe3 O4 nanocomposites in the presence of persulfate and under ultraviolet light-emitting diode (UV-LED) irradiation were applied for reactive red 198 removal with a focus on the main operating parameters such as pH, persulfate molar concentration, irradiation time, and catalyst dosages in different initial concentrations. Methods: The nanoparticles were synthesized by co-precipitation technique. The X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) coupled with energy dispersive X-ray (EDX) and Fourier transform infrared spectroscopy (FTIR) analysis were used to evaluate TiO2 - Fe3 O4 nanocomposites. The response surface methodology (RSM) was employed for modeling and optimization. The kinetics and mechanisms of decolorization by sulfate and hydroxyl radicals were investigated. The mineralization of dye was evaluated using total organic carbon (TOC) analysis. Results: Modeling and optimization through RSM showed that the maximum decolorization of reactive red 198 is accursed an initial concentration of 10-50 mg/L was reached under UV-LED irradiation of 62- 85 min, persulfate concentration=0.8-1 mM, 0.19-0.3 g/L TiO2 -Fe3 O4 nanocomposites concentration, and pH=3. The kinetics of process was in agreement with pseudo-first order. The mineralization of reactive red 198 during the optimum conditions was determined at about 61.1% and 49.6%, meanwhile, the decolorization efficiency in the same conditions was approximately 98.1% and 87.6%, respectively. Conclusion: The use of TiO2 -Fe3 O4 nanocomposites under UV-LED irradiation in the presence of persulfate can be used as an efficient and promising method for dye removal from textile wastewater.
背景:近年来,硫酸盐基光催化工艺因其在污染物净化方面的独特优势而引起了人们的广泛关注。本研究采用TiO2 -Fe3 O4纳米复合材料在过硫酸盐存在下,在紫外发光二极管(UV-LED)照射下对活性红198进行脱除,重点考察了pH、过硫酸盐摩尔浓度、照射时间和不同初始浓度下催化剂用量等主要操作参数。方法:采用共沉淀法合成纳米颗粒。采用x射线衍射(XRD)、场发射扫描电镜(FESEM)、能量色散x射线(EDX)和傅里叶变换红外光谱(FTIR)对TiO2 - fe3o4纳米复合材料进行了表征。采用响应面法(RSM)进行建模和优化。研究了硫酸盐和羟基自由基脱色的动力学和机理。用总有机碳(TOC)分析评价染料的矿化程度。结果:通过RSM建模和优化表明,在UV-LED照射62 ~ 85 min,过硫酸盐浓度为0.8 ~ 1 mM, TiO2 - fe3 O4纳米复合材料浓度为0.19 ~ 0.3 g/L, pH=3的条件下,活性红198的脱色效果最佳,初始浓度为10 ~ 50 mg/L。过程动力学符合准一级动力学。在最佳条件下,活性红198的矿化率分别为61.1%和49.6%,脱色率分别为98.1%和87.6%。结论:在过硫酸盐存在下,紫外- led照射下制备TiO2 -Fe3 O4纳米复合材料是一种高效的脱除纺织废水染料的方法。
{"title":"Activation of persulfate by TiO2 -Fe3 O4 nanocomposite for reactive red 198 degradation along with modeling and optimization approach","authors":"S. Rahimi, F. Mohammadi, Soudabeh Ghodsi, Maryam Mohammadi, H. Karimi","doi":"10.34172/ehem.2023.19","DOIUrl":"https://doi.org/10.34172/ehem.2023.19","url":null,"abstract":"Background: Recently, sulfate radical-based photocatalytic processes have attracted significant interests because of unique advantages in pollutants purification. In this study, TiO2 -Fe3 O4 nanocomposites in the presence of persulfate and under ultraviolet light-emitting diode (UV-LED) irradiation were applied for reactive red 198 removal with a focus on the main operating parameters such as pH, persulfate molar concentration, irradiation time, and catalyst dosages in different initial concentrations. Methods: The nanoparticles were synthesized by co-precipitation technique. The X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) coupled with energy dispersive X-ray (EDX) and Fourier transform infrared spectroscopy (FTIR) analysis were used to evaluate TiO2 - Fe3 O4 nanocomposites. The response surface methodology (RSM) was employed for modeling and optimization. The kinetics and mechanisms of decolorization by sulfate and hydroxyl radicals were investigated. The mineralization of dye was evaluated using total organic carbon (TOC) analysis. Results: Modeling and optimization through RSM showed that the maximum decolorization of reactive red 198 is accursed an initial concentration of 10-50 mg/L was reached under UV-LED irradiation of 62- 85 min, persulfate concentration=0.8-1 mM, 0.19-0.3 g/L TiO2 -Fe3 O4 nanocomposites concentration, and pH=3. The kinetics of process was in agreement with pseudo-first order. The mineralization of reactive red 198 during the optimum conditions was determined at about 61.1% and 49.6%, meanwhile, the decolorization efficiency in the same conditions was approximately 98.1% and 87.6%, respectively. Conclusion: The use of TiO2 -Fe3 O4 nanocomposites under UV-LED irradiation in the presence of persulfate can be used as an efficient and promising method for dye removal from textile wastewater.","PeriodicalId":51877,"journal":{"name":"Environmental Health Engineering and Management Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42461094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence and characteristics of microplastics in surface water and sediment of Zayandeh-rud river, Iran 伊朗Zayandeh-rud河地表水和沉积物中微塑料的存在及其特征
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-12 DOI: 10.34172/ehem.2023.23
Y. Rami, Bahareh Shoshtari-Yeganeh, Afshin Ebrahimi, K. Ebrahimpour
Background: Zayandeh-rud river is the most important river in the central regions of Iran and the present study aimed to provide new insights into microplastics (MPs) pollution in surface water and sediments of this river. Methods: Water and sediment samples were collected in July 2021 from 19 sampling sites along the river. Organics matters were removed from the samples by wet peroxide oxidation (WPO), and MPs were extracted by floatation in ZnCl2 -saturated salt and filtration on a polytetrafluoroethylene (PTFE) membrane filter. Trapped MPs on the filter were counted and qualified by a stereomicroscope. Results: MPs were found in 13 sites from 19 sampling sites along the river. The minimum and maximum levels of MPs in water samples were 0 and 51±16.5 particles/m3 , respectively. MPs also were detected in the sediments of all sampling sites except the first two sampling sites (the maximum level was 58±25.9 particles/kg as dry sediment). Fragments were the most common shape of MPs in both water and sediment samples. 72.3% of MPs detected in water samples were 1-5 mm in size, while this percentage for sediment was 49.2%. The five main polymer types found in water and sediment samples were polyethylene terephthalate (PET), polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyvinyl chloride (PVC). Conclusion: These levels of MPs in the water and sediments of Zayandeh-rud river and longtime persistence of plastics in the environment is a significant threat to environmental and human health and need serious attention to restrict MPs release into the river.
背景:Zayandeh-rud河是伊朗中部地区最重要的河流,本研究旨在为该河地表水和沉积物中的微塑料污染提供新的见解。方法:2021年7月,从沿河19个采样点采集水和沉积物样本。通过湿式过氧化物氧化(WPO)去除样品中的有机物,并通过在ZnCl2-饱和盐中浮选和在聚四氟乙烯(PTFE)膜过滤器上过滤来提取MPs。对过滤器上捕获的MP进行计数,并通过立体显微镜进行鉴定。结果:在沿河19个采样点中的13个采样点发现了MP。水样中MPs的最低和最高水平分别为0和51±16.5个颗粒/m3。除前两个采样点外,在所有采样点的沉积物中也检测到MPs(作为干沉积物,最大水平为58±25.9个颗粒/kg)。碎片是水和沉积物样品中最常见的MPs形状。72.3%的水样中检测到的MPs尺寸为1-5mm,而沉积物的这一百分比为49.2%。在水样和沉积物中发现的五种主要聚合物类型是聚对苯二甲酸乙二醇酯(PET)、聚乙烯(PE)、聚丙烯(PP)、聚苯乙烯(PS)和聚氯乙烯(PVC)。结论:Zayandeh-rud河水体和沉积物中的MPs水平以及塑料在环境中的长期存在对环境和人类健康构成了重大威胁,需要认真注意限制MPs排入河流。
{"title":"Occurrence and characteristics of microplastics in surface water and sediment of Zayandeh-rud river, Iran","authors":"Y. Rami, Bahareh Shoshtari-Yeganeh, Afshin Ebrahimi, K. Ebrahimpour","doi":"10.34172/ehem.2023.23","DOIUrl":"https://doi.org/10.34172/ehem.2023.23","url":null,"abstract":"Background: Zayandeh-rud river is the most important river in the central regions of Iran and the present study aimed to provide new insights into microplastics (MPs) pollution in surface water and sediments of this river. Methods: Water and sediment samples were collected in July 2021 from 19 sampling sites along the river. Organics matters were removed from the samples by wet peroxide oxidation (WPO), and MPs were extracted by floatation in ZnCl2 -saturated salt and filtration on a polytetrafluoroethylene (PTFE) membrane filter. Trapped MPs on the filter were counted and qualified by a stereomicroscope. Results: MPs were found in 13 sites from 19 sampling sites along the river. The minimum and maximum levels of MPs in water samples were 0 and 51±16.5 particles/m3 , respectively. MPs also were detected in the sediments of all sampling sites except the first two sampling sites (the maximum level was 58±25.9 particles/kg as dry sediment). Fragments were the most common shape of MPs in both water and sediment samples. 72.3% of MPs detected in water samples were 1-5 mm in size, while this percentage for sediment was 49.2%. The five main polymer types found in water and sediment samples were polyethylene terephthalate (PET), polyethylene (PE), polypropylene (PP), polystyrene (PS), and polyvinyl chloride (PVC). Conclusion: These levels of MPs in the water and sediments of Zayandeh-rud river and longtime persistence of plastics in the environment is a significant threat to environmental and human health and need serious attention to restrict MPs release into the river.","PeriodicalId":51877,"journal":{"name":"Environmental Health Engineering and Management Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41817094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Specific absorption rate of different phone brands and health students’ awareness, attitude, and performance towards mobile phone hazards 不同手机品牌的具体吸收率与健康学生对手机危害的认知、态度和表现
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-09 DOI: 10.34172/ehem.2023.17
Hiwa Hossaini, Faranak Khodadoost, Soma Goftari
Background: This study aimed to assess the specific absorption rate (SAR) due to the exposure to the radiations from different brands of cellphones, and to compare it with guideline values. The SAR is calculated using the mathematic equation based on the measured energy. Methods: In this regard, 204 cellphones from different brands were randomly surveyed. A questionnaire composed of demographic and self-reported questions was designed to survey the students’ awareness and attitude about cellphone brands, usage duration and observed health effects. The Kolmogorov-Smirnov test was used for statistical analysis at frequencies of 900 and 1800 MHz and the differences between brands were assessed by the Kruskal-Wallis test. Results: According to the results, it was found that 46.7% and 8.4% of people used cellphones for less than 4 and more than 12 hours per day, respectively. According to the statistical tests, students with higher talk time, sent messages, and Internet usage, and those using wireless hands-free, had the most reported symptoms of headache, tinnitus, eye burning and eyestrain, sleep disturbances, and skin color changes. Conclusion: The authors found that there was no significant difference between different brands based on the SAR values. However, Samsung and Nokia brands had the highest SAR values and ASUS brand had the lowest ones. Also, the type of game apps (online/offline) was significantly correlated with possible health effects. Therefore, regarding these cases, as well as the fact that many dangers of cellphone use are unknown, it is recommended to use cellphones cautiously.
背景:本研究旨在评估暴露于不同品牌手机辐射的比吸收率(SAR),并将其与指导值进行比较。利用基于测量能量的数学方程计算SAR。方法:随机抽取204部不同品牌的手机进行调查。设计了一份由人口统计学和自我报告问题组成的问卷,调查学生对手机品牌、使用时间和观察到的健康影响的意识和态度。Kolmogorov-Smirnov检验用于900和1800 MHz频率的统计分析,品牌之间的差异通过Kruskal-Wallis检验进行评估。结果:根据调查结果,46.7%和8.4%的人每天使用手机的时间分别少于4小时和超过12小时。根据统计测试,通话时间、发送信息和互联网使用率较高的学生,以及使用无线免提的学生,出现头痛、耳鸣、眼睛灼热和眼睛疲劳、睡眠障碍和肤色变化的症状最多。结论:作者发现,基于SAR值,不同品牌之间没有显著差异。然而,三星和诺基亚的SAR值最高,华硕的SAR值最低。此外,游戏应用程序的类型(在线/离线)与可能的健康影响显著相关。因此,对于这些情况,以及使用手机的许多危险性是未知的,建议谨慎使用手机。
{"title":"Specific absorption rate of different phone brands and health students’ awareness, attitude, and performance towards mobile phone hazards","authors":"Hiwa Hossaini, Faranak Khodadoost, Soma Goftari","doi":"10.34172/ehem.2023.17","DOIUrl":"https://doi.org/10.34172/ehem.2023.17","url":null,"abstract":"Background: This study aimed to assess the specific absorption rate (SAR) due to the exposure to the radiations from different brands of cellphones, and to compare it with guideline values. The SAR is calculated using the mathematic equation based on the measured energy. Methods: In this regard, 204 cellphones from different brands were randomly surveyed. A questionnaire composed of demographic and self-reported questions was designed to survey the students’ awareness and attitude about cellphone brands, usage duration and observed health effects. The Kolmogorov-Smirnov test was used for statistical analysis at frequencies of 900 and 1800 MHz and the differences between brands were assessed by the Kruskal-Wallis test. Results: According to the results, it was found that 46.7% and 8.4% of people used cellphones for less than 4 and more than 12 hours per day, respectively. According to the statistical tests, students with higher talk time, sent messages, and Internet usage, and those using wireless hands-free, had the most reported symptoms of headache, tinnitus, eye burning and eyestrain, sleep disturbances, and skin color changes. Conclusion: The authors found that there was no significant difference between different brands based on the SAR values. However, Samsung and Nokia brands had the highest SAR values and ASUS brand had the lowest ones. Also, the type of game apps (online/offline) was significantly correlated with possible health effects. Therefore, regarding these cases, as well as the fact that many dangers of cellphone use are unknown, it is recommended to use cellphones cautiously.","PeriodicalId":51877,"journal":{"name":"Environmental Health Engineering and Management Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43568457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Membrane fouling mechanism of submerged membrane bioreactor during erythromycin removal 浸没式膜生物反应器去除红霉素过程中的膜污染机理
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-04 DOI: 10.34172/ehem.2023.20
Hajar Aghili Dehnavi, A. Fatehizadeh, M. Amin, H. Movahedian Attar, K. Ebrahimpour, B. Bina
Background: Based on the previous studies, antibiotics can have affected biological properties of biomass and fouling properties of mixed liquor in aeration tank. The present study was conducted to explore the fouling mechanisms of membrane bioreactor (MBR) system during the treatment of wastewater containing erythromycin (ERY) antibiotic under several mixed liquor suspended solids (MLSS) concentrations. Methods: A lab-scale two-chamber MBR system equipped with a polypropylene hollow fiber submerged membrane was fed with synthetic wastewater containing different initial concentrations of ERY. MBR system was operated under the constant flux mode and different MLSS concentrations (5.0-13.0 g/L) and the obtained results were evaluated using different individual and combined fouling models. Results: The variation of MLSS concentrations had not significantly affected the kind of best-fitted model. From the individual models, the standard model indicated the best performance for permeate prediction under different MLSS concentrations (R2 adj>0.997). For all studied MLSS concentrations, the R2 adj values of combined fouling models were higher than 0.986 and demonstrated good fitness performance of combined models compared to individual models. Overall, the cake-intermediate model showed the lowest fitness, and cake-complete and complete-standard models were the most successful models in filtrated volume prediction in comparison with other combined fouling models. Conclusion: This study indicated that mechanistic models are suitable for fouling prediction of MBR systems in ERY removal and under a wide range of MLSS concentrations and provide valuable information on fouling mechanisms of full-scale MBR systems.
背景:根据以往的研究,抗生素可能会影响生物质的生物学特性和曝气池混合液的污染特性。研究了膜生物反应器(MBR)系统在不同混液悬浮物(MLSS)浓度下处理含红霉素(ERY)抗生素废水的污染机理。方法:以含不同初始浓度的ERY合成废水为原料,采用聚丙烯中空纤维浸没膜,建立实验室规模的双室MBR系统。在恒通量模式和不同浓度(5.0 ~ 13.0 g/L) MLSS下运行MBR系统,并采用不同的单独和组合污染模型对所得结果进行评价。结果:MLSS浓度的变化对最佳拟合模型的类型没有显著影响。从各模型来看,标准模型在不同MLSS浓度下的渗透率预测效果最佳(R2 = >0.997)。在所有研究的MLSS浓度下,组合污染模型的R2 adj值均大于0.986,与单个模型相比,组合模型具有良好的适应度。总体而言,饼-中间模型适应度最低,饼完全模型和完全标准模型与其他组合污染模型相比,在过滤体积预测方面最成功。结论:本研究表明,机制模型适用于MBR系统在ERY去除和大范围MLSS浓度下的污染预测,并为大规模MBR系统的污染机理提供了有价值的信息。
{"title":"Membrane fouling mechanism of submerged membrane bioreactor during erythromycin removal","authors":"Hajar Aghili Dehnavi, A. Fatehizadeh, M. Amin, H. Movahedian Attar, K. Ebrahimpour, B. Bina","doi":"10.34172/ehem.2023.20","DOIUrl":"https://doi.org/10.34172/ehem.2023.20","url":null,"abstract":"Background: Based on the previous studies, antibiotics can have affected biological properties of biomass and fouling properties of mixed liquor in aeration tank. The present study was conducted to explore the fouling mechanisms of membrane bioreactor (MBR) system during the treatment of wastewater containing erythromycin (ERY) antibiotic under several mixed liquor suspended solids (MLSS) concentrations. Methods: A lab-scale two-chamber MBR system equipped with a polypropylene hollow fiber submerged membrane was fed with synthetic wastewater containing different initial concentrations of ERY. MBR system was operated under the constant flux mode and different MLSS concentrations (5.0-13.0 g/L) and the obtained results were evaluated using different individual and combined fouling models. Results: The variation of MLSS concentrations had not significantly affected the kind of best-fitted model. From the individual models, the standard model indicated the best performance for permeate prediction under different MLSS concentrations (R2 adj>0.997). For all studied MLSS concentrations, the R2 adj values of combined fouling models were higher than 0.986 and demonstrated good fitness performance of combined models compared to individual models. Overall, the cake-intermediate model showed the lowest fitness, and cake-complete and complete-standard models were the most successful models in filtrated volume prediction in comparison with other combined fouling models. Conclusion: This study indicated that mechanistic models are suitable for fouling prediction of MBR systems in ERY removal and under a wide range of MLSS concentrations and provide valuable information on fouling mechanisms of full-scale MBR systems.","PeriodicalId":51877,"journal":{"name":"Environmental Health Engineering and Management Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43472737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Removal of cadmium from aqueous solution using nano Prosopis cineraria leaf ash (NPCLA) 利用纳米灰叶藻(NPCLA)去除水溶液中的镉
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-03 DOI: 10.34172/ehem.2023.25
M. Pourjaafar, A. Askari, A. Salehi Sahl Abadi, B. Anvaripour, Afshar Nemati, S. A. Rahimi, Mona Pourjafar
Background: Heavy metal pollution has become one of the most severe environmental problems, therefore, the present study was conducted to investigate removal of cadmium (Cd) from aqueous solution. Methods: In the present study, nano Prosopis cineraria leaf ash (NPCLA) was used as an adsorbent for removing Cd from aqueous solution. Contact time, initial pH of the solutions, sorbent dosages, and initial Cd (II) concentration were considered as parameters affecting Cd removal efficiency. The experiments were designed by Design of Expert (DOE) software. Results: It was revealed that an NPCLA dosage of 2.45 gL-1, pH of 6.3, and initial Cd (II) concentration of 20.7 mgL-1 in contact time of 60 min was the optimum condition for removal of Cd (II) in the domain of experiments and at this optimum condition, the prediction value of removal efficiency was found 99.9%. Based on the results of kinetics experiments, the sorption system and experiment data of Cd (II) adsorption on the NPCLA followed the pseudo-second-order kinetic model. Freundlich, Langmuir, Brunauer-Emmett-Teller (BET), and Temkin isotherm models were investigated. The equilibrium adsorption data were fitted well with linearly transformed Langmuir isotherm with a correlation coefficient of R2=0.9877, and the maximum sorption capacity of NPCLA was obtained to be 25.25 mgg-1. Conclusion: In laboratory conditions, NPCLA can remove Cd from aqueous solution with a high efficiency. Therefore, due to this plant’s availability and cheapness, NPCLA can be considered a suitable option for producing adsorbents on industrial scales.
背景:重金属污染已成为最严重的环境问题之一,因此,本研究旨在研究水溶液中镉的去除。方法:采用纳米灰松叶灰(NPCLA)作为吸附剂对水溶液中的镉进行吸附。接触时间、溶液的初始pH、吸附剂用量和初始Cd(II)浓度被认为是影响Cd去除效率的参数。实验采用专家设计软件进行设计。结果:NPCLA用量为2.45gL-1,pH为6.3,初始Cd(II)浓度为20.7mgL-1,接触时间为60min,是实验领域中去除Cd(Ⅱ)的最佳条件,在该最佳条件下,去除效率的预测值为99.9%,Cd(II)在NPCLA上的吸附体系和实验数据遵循准二阶动力学模型。研究了Freundlich、Langmuir、Brunauer-Emmett-Teller(BET)和Temkin等温线模型。平衡吸附数据与线性变换的Langmuir等温线拟合良好,相关系数为R2=0.9877,NPCLA的最大吸附容量为25.25mg-1。结论:在实验室条件下,NPCLA能高效去除水溶液中的镉。因此,由于该装置的可用性和廉价性,NPCLA可以被认为是在工业规模上生产吸附剂的合适选择。
{"title":"Removal of cadmium from aqueous solution using nano Prosopis cineraria leaf ash (NPCLA)","authors":"M. Pourjaafar, A. Askari, A. Salehi Sahl Abadi, B. Anvaripour, Afshar Nemati, S. A. Rahimi, Mona Pourjafar","doi":"10.34172/ehem.2023.25","DOIUrl":"https://doi.org/10.34172/ehem.2023.25","url":null,"abstract":"Background: Heavy metal pollution has become one of the most severe environmental problems, therefore, the present study was conducted to investigate removal of cadmium (Cd) from aqueous solution. Methods: In the present study, nano Prosopis cineraria leaf ash (NPCLA) was used as an adsorbent for removing Cd from aqueous solution. Contact time, initial pH of the solutions, sorbent dosages, and initial Cd (II) concentration were considered as parameters affecting Cd removal efficiency. The experiments were designed by Design of Expert (DOE) software. Results: It was revealed that an NPCLA dosage of 2.45 gL-1, pH of 6.3, and initial Cd (II) concentration of 20.7 mgL-1 in contact time of 60 min was the optimum condition for removal of Cd (II) in the domain of experiments and at this optimum condition, the prediction value of removal efficiency was found 99.9%. Based on the results of kinetics experiments, the sorption system and experiment data of Cd (II) adsorption on the NPCLA followed the pseudo-second-order kinetic model. Freundlich, Langmuir, Brunauer-Emmett-Teller (BET), and Temkin isotherm models were investigated. The equilibrium adsorption data were fitted well with linearly transformed Langmuir isotherm with a correlation coefficient of R2=0.9877, and the maximum sorption capacity of NPCLA was obtained to be 25.25 mgg-1. Conclusion: In laboratory conditions, NPCLA can remove Cd from aqueous solution with a high efficiency. Therefore, due to this plant’s availability and cheapness, NPCLA can be considered a suitable option for producing adsorbents on industrial scales.","PeriodicalId":51877,"journal":{"name":"Environmental Health Engineering and Management Journal","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49300568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic resistance, virulence factors, and phylogenetic groups of Escherichia coli isolated from hospital wastewater: A case study in the west of Iran 从医院废水中分离的大肠杆菌的抗生素耐药性、毒力因子和系统发育群:伊朗西部的一个案例研究
IF 1.6 Q2 Environmental Science Pub Date : 2023-04-01 DOI: 10.34172/ehem.2023.15
A. Bozorgomid, Roya Chegene Lorestani, M. Rostamian, Fatemeh Nemati Zargaran, Zhila Shahvaisi-Zadeh, A. Akya
Background: The appropriate management of hospital wastewater is an essential process to prevent the spread of pathogenic strains of bacteria including Escherichia coli in this study, the antibiotic resistance, virulence characteristics, and phylogenetic diversity of E. coli isolated from the raw and treated hospital wastewater in a general hospital in the west of Iran were evaluated. Methods: E. coli isolates were recovered and identified using culture and biochemical tests. Sixty isolates were used and antimicrobial resistance, virulence genes, antibiotic-resistant genes (ARGs), and phylogeny groups of isolates were determined using polymerase chain reaction (PCR) assay. The antibiotic resistance was tested using disk diffusion. Results: The antibiotic susceptibility testing indicated that the resistance to co-trimoxazole was the most common, followed by ceftriaxone, amikacin, and gentamicin. Multi-drug resistance (MDR) was observed in 90% of raw and 96.66% of treated sewage isolates. The phylogeny groups B1 and A were the most common groups among isolates of raw and treated sewage, respectively. The most common virulence genes detected were sfa, papC, and fyuA; while pic and sepA genes were not found in the isolates. The most common ARGs were blaTEM (in 90% isolates of raw and 92.5% of treated sewage) and blaCTX-M (in 60% isolates of raw and 77.5% of treated sewage). The blaSHV-5 gene was not detected among isolates. Conclusion: The results highlight the potential of hospital wastewater as a source for spreading the virulent and multi drug-resistant strains of E. coli.
背景:对医院废水进行适当的管理是防止包括大肠杆菌在内的病原菌传播的必要过程。本研究对伊朗西部一家综合医院未经处理的医院废水中分离的大肠杆菌的抗生素耐药性、毒力特征和系统发育多样性进行了评估。方法:采用培养和生化试验对分离的大肠杆菌进行回收和鉴定。采用聚合酶链反应(PCR)法对60株菌株进行耐药性、毒力基因、耐药基因(ARGs)和系统发育类群测定。采用纸片扩散法检测抗生素耐药性。结果:药敏试验结果显示,耐药最多的是复方新诺明,其次是头孢曲松、阿米卡星和庆大霉素。90%的生分离菌株和96.66%的处理过的污水分离菌株存在多药耐药(MDR)。系统发育类群B1和A分别是原污水和处理污水分离株中最常见的类群。最常见的毒力基因为sfa、papC和fyuA;而在分离株中未发现pic和sepA基因。最常见的ARGs是blaTEM(90%的分离株和92.5%的处理污水)和blaCTX-M(60%的分离株和77.5%的处理污水)。分离株中未检出blaSHV-5基因。结论:医院废水有可能成为大肠杆菌强毒和多重耐药菌株的传播源。
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Environmental Health Engineering and Management Journal
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