Background: The presence of risk factors have a high risk of developing breast cancer. Our study aimed to find an association between sociodemographic factors and the risk of estrogen receptor (ER)-positive, progesterone receptor (PR)positive breast cancer among women. Methods: A cross-sectional study was conducted on 200 women with breast cancer. Association between sociodemographic factors and hormone receptor subtypes of breast cancer was found using the Chisquare test. Multiple logistic regression analysis was used to know the strong predictors of hormone receptor subtypes. Results: The mean age was 50.08 (10.67) years. Comorbidities had a statistically significant association with ER-positive subtype (p = 0.007). Body mass index had a statistically significant association with PR-positive subtype (p = 0.042). Comorbidities was found to be the strong independent predictor for ER-positive (OR 2.28; 95% CI: 1.28–4.05, p = 0.01) and PR-positive subtypes (OR 1.78; 95% CI: 1.01–3.13, p = 0.03). Conclusion: We conclude that in our study, body mass index was associated with PR-positive subtype, and comorbidities were associated with ER-positive subtype of breast cancer among the women. Comorbidities remained to be a strong independent predictor of ER-positive and PRpositive subtypes of breast cancer.
背景:存在高危因素的人患乳腺癌的风险较高。我们的研究旨在发现社会人口学因素与女性雌激素受体(ER)阳性、孕激素受体(PR)阳性乳腺癌风险之间的关系。方法:对200例乳腺癌患者进行横断面研究。使用Chisquare检验发现社会人口学因素与乳腺癌激素受体亚型之间存在关联。采用多元logistic回归分析了解激素受体亚型的强预测因子。结果:患者平均年龄为50.08(10.67)岁。合并症与er阳性亚型的相关性有统计学意义(p = 0.007)。体重指数与pr阳性亚型有统计学意义(p = 0.042)。合并症是er阳性的独立预测因子(OR 2.28;95% CI: 1.28-4.05, p = 0.01)和pr阳性亚型(OR 1.78;95% CI: 1.01-3.13, p = 0.03)。结论:在我们的研究中，体重指数与pr阳性亚型相关，合并症与er阳性亚型乳腺癌相关。合并症仍然是雌激素受体阳性和雌激素受体阳性乳腺癌亚型的一个强有力的独立预测因子。
{"title":"Association between sociodemographic factors and estrogen receptor-positive, progesterone receptor-positive breast cancer subtypes: A cross-sectional study","authors":"Vinodkumar Mugada, R. Kolakota, Varsha Mahato","doi":"10.7454/msk.v24i2.1213","DOIUrl":"https://doi.org/10.7454/msk.v24i2.1213","url":null,"abstract":"Background: The presence of risk factors have a high risk of developing breast cancer. Our study aimed to find an association between sociodemographic factors and the risk of estrogen receptor (ER)-positive, progesterone receptor (PR)positive breast cancer among women. Methods: A cross-sectional study was conducted on 200 women with breast cancer. Association between sociodemographic factors and hormone receptor subtypes of breast cancer was found using the Chisquare test. Multiple logistic regression analysis was used to know the strong predictors of hormone receptor subtypes. Results: The mean age was 50.08 (10.67) years. Comorbidities had a statistically significant association with ER-positive subtype (p = 0.007). Body mass index had a statistically significant association with PR-positive subtype (p = 0.042). Comorbidities was found to be the strong independent predictor for ER-positive (OR 2.28; 95% CI: 1.28–4.05, p = 0.01) and PR-positive subtypes (OR 1.78; 95% CI: 1.01–3.13, p = 0.03). Conclusion: We conclude that in our study, body mass index was associated with PR-positive subtype, and comorbidities were associated with ER-positive subtype of breast cancer among the women. Comorbidities remained to be a strong independent predictor of ER-positive and PRpositive subtypes of breast cancer.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"24 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88944171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. S. Nurumal, Rohulizzat Zainal Abidin, W. N. Ibrahim, M. Isa, M. K. Hasan
Background: Overweight and obesity, which may lead to depression, have become prevalent among children worldwide. Hence, this study aimed to measure obesity and depression among schoolchildren in Kuantan. Methods: This cross-sectional study was conducted in three different primary schools in Kuantan by purposive sampling. With consent from their parents/guardians, participants were given a self-administered questionnaire. Demographics and anthropometric measurement data were self-reported on the basis of the school records. Furthermore, body mass index was calculated. Data were analyzed using SPSS version 20.0, and chi-square and correlation tests were conducted for the variables. Results: Among the 300 schoolchildren who responded, 14.3% were underweight, 37.7% were normal, 11% were overweight, and 37% were obese. Statistically, obesity and ethnicity, as well as obesity and sex, were not associated. Conversely, obesity and age, as well as obesity and depression, were significantly associated. Conclusion: Depression is associated with obesity among schoolchildren. Hence, a special approach for designing and implementing prevention programs is necessary to reduce the risk of obesity-led depression and other forms of comorbidity later in life.
{"title":"Obesity is associated with depression in Malaysian schoolchildren: A cross-sectional study","authors":"M. S. Nurumal, Rohulizzat Zainal Abidin, W. N. Ibrahim, M. Isa, M. K. Hasan","doi":"10.7454/msk.v24i1.1173","DOIUrl":"https://doi.org/10.7454/msk.v24i1.1173","url":null,"abstract":"Background: Overweight and obesity, which may lead to depression, have become prevalent among children worldwide. Hence, this study aimed to measure obesity and depression among schoolchildren in Kuantan. \u0000 \u0000Methods: This cross-sectional study was conducted in three different primary schools in Kuantan by purposive sampling. With consent from their parents/guardians, participants were given a self-administered questionnaire. Demographics and anthropometric measurement data were self-reported on the basis of the school records. Furthermore, body mass index was calculated. Data were analyzed using SPSS version 20.0, and chi-square and correlation tests were conducted for the variables. \u0000 \u0000Results: Among the 300 schoolchildren who responded, 14.3% were underweight, 37.7% were normal, 11% were overweight, and 37% were obese. Statistically, obesity and ethnicity, as well as obesity and sex, were not associated. Conversely, obesity and age, as well as obesity and depression, were significantly associated. \u0000 \u0000Conclusion: Depression is associated with obesity among schoolchildren. Hence, a special approach for designing and implementing prevention programs is necessary to reduce the risk of obesity-led depression and other forms of comorbidity later in life.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"2 1","pages":"2"},"PeriodicalIF":0.4,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73305507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Teenagers are influenced by their surroundings, and this may also include their sexual behavior or societal responses to this type of behavior. It is important to understand the complexity of religious mandates and sociocultural disapproval of premarital sex from the perspectives of healthcare professionals. Methods: This qualitative study aimed to explore the influence of religion on healthcare professional’s beliefs toward providing sexual and reproductive health information and treatment. An interview topic guide was used in the in-depth interview of 32 healthcare professionals in several health clinics in Malaysia. The data were transcribed and entered into the NVivo 11 software. Thematic analysis was used to evaluate the data. Results: The findings show that some healthcare professionals positively incorporated Islamic beliefs into sexual health education session but excluded the contraception information. This study also highlights the strategies used by healthcare professionals (discourse on risk, being selective, maintaining their own honor) when providing sexual health services to teenagers. Conclusion: These findings revealed how religion perpetuates a “moral” approach in the provision of sexual health services that potentially affects teenagers’ access to healthcare.
{"title":"Influence of religion on healthcare professionals’ beliefs toward teenage sexual practices in Malaysia","authors":"Siti Suhaila Abdul Hamid, D. Fallon, P. Callery","doi":"10.7454/msk.v24i1.1175","DOIUrl":"https://doi.org/10.7454/msk.v24i1.1175","url":null,"abstract":"Background: Teenagers are influenced by their surroundings, and this may also include their sexual behavior or societal responses to this type of behavior. It is important to understand the complexity of religious mandates and sociocultural disapproval of premarital sex from the perspectives of healthcare professionals. Methods: This qualitative study aimed to explore the influence of religion on healthcare professional’s beliefs toward providing sexual and reproductive health information and treatment. An interview topic guide was used in the in-depth interview of 32 healthcare professionals in several health clinics in Malaysia. The data were transcribed and entered into the NVivo 11 software. Thematic analysis was used to evaluate the data. Results: The findings show that some healthcare professionals positively incorporated Islamic beliefs into sexual health education session but excluded the contraception information. This study also highlights the strategies used by healthcare professionals (discourse on risk, being selective, maintaining their own honor) when providing sexual health services to teenagers. Conclusion: These findings revealed how religion perpetuates a “moral” approach in the provision of sexual health services that potentially affects teenagers’ access to healthcare.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"21 1","pages":"27-34"},"PeriodicalIF":0.4,"publicationDate":"2020-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90053594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharifah Munirah Syed Elias, N. Jaafar, Lee Siew Pien
Background: The aging population is increasing globally and requires a high demand for healthcare services in several countries. As a way of preparing future nurses in aged care, substantial incorporation of gerontology courses in the nursing program to meet future needs is required. The present study aimed to investigate the association between attitudes and work preferences toward older people among undergraduate nursing students. Methods: A cross-sectional study was conducted involving 291 nursing students at a Malaysian public university. A set of questionnaires was used that comprised the following three parts: (1) Part A: Sociodemographic background, (2) Part B: Attitudes toward older people, and (3) Part C: Nursing students’ work preferences. Results: Most of the participants (80.4%) demonstrated slightly positive attitudes on older people. Only 2.4% selected older people group as their work preference. There were no significant associations between attitudes with sex (p = 0.84), year of study (p = 0.30), living status (p = 0.77), and work preferences (p = 0.81). Conclusion: Overall, the majority of participants had slightly positive attitudes on older people. Although they had positive attitudes on older people, working in aged care setting is not their first preference after their graduation.
{"title":"Attitudes and work preferences toward older people among Malay undergraduate nursing students","authors":"Sharifah Munirah Syed Elias, N. Jaafar, Lee Siew Pien","doi":"10.7454/msk.v24i3.1227","DOIUrl":"https://doi.org/10.7454/msk.v24i3.1227","url":null,"abstract":"Background: The aging population is increasing globally and requires a high demand for healthcare services in several countries. As a way of preparing future nurses in aged care, substantial incorporation of gerontology courses in the nursing program to meet future needs is required. The present study aimed to investigate the association between attitudes and work preferences toward older people among undergraduate nursing students. Methods: A cross-sectional study was conducted involving 291 nursing students at a Malaysian public university. A set of questionnaires was used that comprised the following three parts: (1) Part A: Sociodemographic background, (2) Part B: Attitudes toward older people, and (3) Part C: Nursing students’ work preferences. Results: Most of the participants (80.4%) demonstrated slightly positive attitudes on older people. Only 2.4% selected older people group as their work preference. There were no significant associations between attitudes with sex (p = 0.84), year of study (p = 0.30), living status (p = 0.77), and work preferences (p = 0.81). Conclusion: Overall, the majority of participants had slightly positive attitudes on older people. Although they had positive attitudes on older people, working in aged care setting is not their first preference after their graduation.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"23 1","pages":"8"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88747861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artemio M. Gonzales, R. M. Ambong, L. Bais, Lendon Perez Macaspac
Background: Health is an integral form of human capital that can positively influence agricultural worker productivity in the physical, mental, and social domains. Poor health usually represents a burden to farm workers because a failure to meet scheduled tasks on the farm can later affect the dependents who rely on it for food nourishment and sustained livelihood. This study aims to determine the association between health and the work capabilities of smallholder rice farm workers in San Jose, Occidental Mindoro, Philippines. Methods: A cross sectional study was conducted among 100 farm workers. The SF-36 (HRQoL) and Work Ability Index (WAI) questionnaires were used to determine health status and work abilities of the respondents. The association of every health domain was investigated using one-way analysis of variance (ANOVA). Results: The results show that work ability was more associated with physical functioning and vitality scales compared to physical role limitations, bodily pain, general health perceptions, social functioning, emotional role limitations, and mental health in the health dimensions. Conclusion: Given the influence of health-related quality of life, any intervention program for the safeguarding and promotion of work ability among farmers should be based on balancing and optimizing the physical and psychosocial work environments.
{"title":"Health-related quality of life and work ability of smallholder rice farm workers in San Jose, Occidental Mindoro, Philippines","authors":"Artemio M. Gonzales, R. M. Ambong, L. Bais, Lendon Perez Macaspac","doi":"10.7454/msk.v24i2.1203","DOIUrl":"https://doi.org/10.7454/msk.v24i2.1203","url":null,"abstract":"Background: Health is an integral form of human capital that can positively influence agricultural worker productivity in the physical, mental, and social domains. Poor health usually represents a burden to farm workers because a failure to meet scheduled tasks on the farm can later affect the dependents who rely on it for food nourishment and sustained livelihood. This study aims to determine the association between health and the work capabilities of smallholder rice farm workers in San Jose, Occidental Mindoro, Philippines. Methods: A cross sectional study was conducted among 100 farm workers. The SF-36 (HRQoL) and Work Ability Index (WAI) questionnaires were used to determine health status and work abilities of the respondents. The association of every health domain was investigated using one-way analysis of variance (ANOVA). Results: The results show that work ability was more associated with physical functioning and vitality scales compared to physical role limitations, bodily pain, general health perceptions, social functioning, emotional role limitations, and mental health in the health dimensions. Conclusion: Given the influence of health-related quality of life, any intervention program for the safeguarding and promotion of work ability among farmers should be based on balancing and optimizing the physical and psychosocial work environments.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"17 1","pages":"5"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77742658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Minhas, Aneequa Sajjad, M. Kashif, Zobaria Rehman, M. Idrees, F. Ansari
Background: In developing countries like Pakistan, it is essential for health care professionals to have comprehensive knowledge regarding cervical cancer. Methods: A cross-sectional self-administered paper-based questionnaire was administered to patients from 2016 to 2018. This study included 200 females who attended the gynecological OPD of Lady Willingdon Hospital Lahore, Punjab. We evaluated cervical cancer knowledge, screening, prevention, and acceptance towards the vaccination. Data entry and analysis were performed using SPSS version 20. Results: The perception and knowledge related to cervical cancer (28%), screening (3%), prevention (3%), and vaccination (1%) among the females were poor, but a positive attitude was observed towards cervical cancer screening, vaccination, and awareness programs. An extreme lack of knowledge was observed regarding the risk factors associated with cervical cancer and the availability of the cervical cancer vaccine (99%). A significant association (p > 0.005) was noted among the level of education and awareness of cervical cancer, its mode of transmission, and screening tests. Conclusion: The knowledge and perception of cervical cancer and its vaccine among the females of Punjab, Pakistan were inadequate. Efforts should be made to prevent and control cervical cancer in Pakistan by establishing proper strategies, such as health education programs through health care providers and media support.
背景:在巴基斯坦等发展中国家，卫生保健专业人员对宫颈癌有全面的了解是至关重要的。方法:对2016 - 2018年患者进行横断面自填纸质问卷调查。本研究包括旁遮普省拉合尔威灵顿夫人医院妇科门诊的200名妇女。我们评估宫颈癌的知识，筛查，预防和接受疫苗接种。数据录入和分析使用SPSS version 20进行。结果:女性对宫颈癌的认知和知识(28%)、筛查(3%)、预防(3%)和疫苗接种(1%)较差，但对宫颈癌筛查、疫苗接种和宣传项目持积极态度。对与宫颈癌有关的危险因素和宫颈癌疫苗的可得性极度缺乏了解(99%)。注意到对宫颈癌的教育和认识水平、其传播方式和筛查试验之间存在显著关联(p > 0.005)。结论:巴基斯坦旁遮普省女性对宫颈癌及其疫苗的认识和认知不足。巴基斯坦应该努力通过制定适当的战略来预防和控制子宫颈癌，例如通过卫生保健提供者和媒体支持开展健康教育项目。
{"title":"Cervical cancer vaccination awareness and acceptance among the females of Punjab, Pakistan","authors":"S. Minhas, Aneequa Sajjad, M. Kashif, Zobaria Rehman, M. Idrees, F. Ansari","doi":"10.7454/msk.v24i1.1164","DOIUrl":"https://doi.org/10.7454/msk.v24i1.1164","url":null,"abstract":"Background: In developing countries like Pakistan, it is essential for health care professionals to have comprehensive knowledge regarding cervical cancer. Methods: A cross-sectional self-administered paper-based questionnaire was administered to patients from 2016 to 2018. This study included 200 females who attended the gynecological OPD of Lady Willingdon Hospital Lahore, Punjab. We evaluated cervical cancer knowledge, screening, prevention, and acceptance towards the vaccination. Data entry and analysis were performed using SPSS version 20. Results: The perception and knowledge related to cervical cancer (28%), screening (3%), prevention (3%), and vaccination (1%) among the females were poor, but a positive attitude was observed towards cervical cancer screening, vaccination, and awareness programs. An extreme lack of knowledge was observed regarding the risk factors associated with cervical cancer and the availability of the cervical cancer vaccine (99%). A significant association (p > 0.005) was noted among the level of education and awareness of cervical cancer, its mode of transmission, and screening tests. Conclusion: The knowledge and perception of cervical cancer and its vaccine among the females of Punjab, Pakistan were inadequate. Efforts should be made to prevent and control cervical cancer in Pakistan by establishing proper strategies, such as health education programs through health care providers and media support.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"17 1","pages":"8"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80191665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Tew, C. L. Goo, S. M. Said, Hafizul Izwan Zahari, N. A. Ali, Fatin Athirah Masawi, A. Aziz, T. Dom
Background: Despite being a common problem, long-term disability following stroke often improves after survivors receive regular rehabilitative therapy. This study aimed to assess the oral health-related quality of life (OHRQoL) of stroke survivors who had access to a community-based rehabilitation centre after hospital discharge. Methods: Dentate post-stroke patients receiving regular rehabilitative care with slight to moderate dependency (Barthel Index >70) and without severe cognitive impairment were involved in this study. The OHRQoL parameters were measured using the Oral Health Impact Profile-14 (OHIP-14) and EuroQol five dimensions (EQ-5D-5L) questionnaires. Results: Thirty one patients were recruited in this study. Majority of the patients hardly ever or never had problems in all functional, physical, psychological and social domains, including eating discomfort and having to avoid eating, difficulty in chewing food and presumably having bad breath (58.1%, 61.3% and 71.0% respectively). Other than gender, age, ethnicity, co-morbidities and oral hygiene practices, education level was the only variable found to significantly affect patients’ OHRQoL (p = 0.028). Most of the patients had no or slight problem(s) in self-care (87.1%) and carrying out usual activities (57.1%), pain/discomfort (3.2%) and anxiety/depression (6.5%). Conclusion: Stroke survivors under regular rehabilitative care perceived have good oral health-related quality of life.
{"title":"Oral health related quality of life in stroke survivors at community-based rehabilitation centre: A pilot study","authors":"I. Tew, C. L. Goo, S. M. Said, Hafizul Izwan Zahari, N. A. Ali, Fatin Athirah Masawi, A. Aziz, T. Dom","doi":"10.7454/msk.v24i1.1181","DOIUrl":"https://doi.org/10.7454/msk.v24i1.1181","url":null,"abstract":"Background: Despite being a common problem, long-term disability following stroke often improves after survivors receive regular rehabilitative therapy. This study aimed to assess the oral health-related quality of life (OHRQoL) of stroke survivors who had access to a community-based rehabilitation centre after hospital discharge. Methods: Dentate post-stroke patients receiving regular rehabilitative care with slight to moderate dependency (Barthel Index >70) and without severe cognitive impairment were involved in this study. The OHRQoL parameters were measured using the Oral Health Impact Profile-14 (OHIP-14) and EuroQol five dimensions (EQ-5D-5L) questionnaires. Results: Thirty one patients were recruited in this study. Majority of the patients hardly ever or never had problems in all functional, physical, psychological and social domains, including eating discomfort and having to avoid eating, difficulty in chewing food and presumably having bad breath (58.1%, 61.3% and 71.0% respectively). Other than gender, age, ethnicity, co-morbidities and oral hygiene practices, education level was the only variable found to significantly affect patients’ OHRQoL (p = 0.028). Most of the patients had no or slight problem(s) in self-care (87.1%) and carrying out usual activities (57.1%), pain/discomfort (3.2%) and anxiety/depression (6.5%). Conclusion: Stroke survivors under regular rehabilitative care perceived have good oral health-related quality of life.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"38 1","pages":"4"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83111449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Alsaqri, Eddieson Pasay-an, L. Villacorte, Fredezwinda Madjid, C. Pacis, Ahmad K. Al-Sadi
Background: This study aimed to determine the differences in the workplace empowerment of nursing faculty as it relates to their demographic information. Methods: A comparative cross-sectional study was conducted among 65 nurse educators at the College of Nursing, University of Hail, Saudi Arabia. The data were collected through a survey questionnaire between January and March 2019. Results: Significant differences were found regarding gender and opportunity (p < 0.017), support (p < 0.020), resources (p < 0.022), job activities scale (JAS; p < 0.005), organizational relationship scale (ORS; p < 0.011), and marital status on resources (p < 0.031). In comparison, gender to information and all of the other demographic variables such as marital status (except resources), years of experience, age, nationality, educational qualifications, and specialization were found insignificant to opportunity, support, resources, information, JAS, and ORS, where all of their p-values were more than 0.05. Conclusion: Male nursing faculty were found to be more empowered in terms of opportunity, support, resources, JAS, and ORS but not to information. Married nursing faculty were found more empowered only to resources. This study supports that gender and information, marital status (except resources), years of experience, age, nationality, educational qualifications, and specialization are not determinants for job empowerment.
{"title":"Organizational empowerment among Nursing Faculty in the Northwestern Region of Saudi Arabia","authors":"S. Alsaqri, Eddieson Pasay-an, L. Villacorte, Fredezwinda Madjid, C. Pacis, Ahmad K. Al-Sadi","doi":"10.7454/msk.v24i2.1205","DOIUrl":"https://doi.org/10.7454/msk.v24i2.1205","url":null,"abstract":"Background: This study aimed to determine the differences in the workplace empowerment of nursing faculty as it relates to their demographic information. Methods: A comparative cross-sectional study was conducted among 65 nurse educators at the College of Nursing, University of Hail, Saudi Arabia. The data were collected through a survey questionnaire between January and March 2019. Results: Significant differences were found regarding gender and opportunity (p < 0.017), support (p < 0.020), resources (p < 0.022), job activities scale (JAS; p < 0.005), organizational relationship scale (ORS; p < 0.011), and marital status on resources (p < 0.031). In comparison, gender to information and all of the other demographic variables such as marital status (except resources), years of experience, age, nationality, educational qualifications, and specialization were found insignificant to opportunity, support, resources, information, JAS, and ORS, where all of their p-values were more than 0.05. Conclusion: Male nursing faculty were found to be more empowered in terms of opportunity, support, resources, JAS, and ORS but not to information. Married nursing faculty were found more empowered only to resources. This study supports that gender and information, marital status (except resources), years of experience, age, nationality, educational qualifications, and specialization are not determinants for job empowerment.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"22 1","pages":"7"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84358519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Many elderly individuals receive lifelong treatment caused by chronic diseases with symptoms that affecting them physically, psychologically, socially, and spiritually. Spirituality plays an essential role in health conditions and social relationships given that it provides meaning to the elderly individuals life by allowing them to see the wisdom of life events experienced. This research aimed to explore the meaning of life among elderly individuals with chronic diseases. Methods: This research applied descriptive phenomenology using Colaizzi’s method of thematic analysis among 13 elderly patients with chronic diseases. Results: Elderly individuals with chronic diseases found meaning through the following items: (1) surrender to God, (2) divine destiny, (3) care until death, (4) guarantee for health finance, (5) role replacement, and (6) observing the development of children and grandchildren. Conclusion: Elderly individuals with chronic diseases can obtained positive meaning in life through family support. Families are thus expected to facilitate the development of meaning in the lives of elderly individuals with chronic diseases to help them fulfill their spiritual needs.
{"title":"Meaning of life among elderly individuals with chronic diseases living with family: A qualitative study","authors":"B. Bahtiar, J. Sahar, Wiwin Wiarsih","doi":"10.7454/msk.v24i1.1161","DOIUrl":"https://doi.org/10.7454/msk.v24i1.1161","url":null,"abstract":"Background: Many elderly individuals receive lifelong treatment caused by chronic diseases with symptoms that affecting them physically, psychologically, socially, and spiritually. Spirituality plays an essential role in health conditions and social relationships given that it provides meaning to the elderly individuals life by allowing them to see the wisdom of life events experienced. This research aimed to explore the meaning of life among elderly individuals with chronic diseases. Methods: This research applied descriptive phenomenology using Colaizzi’s method of thematic analysis among 13 elderly patients with chronic diseases. Results: Elderly individuals with chronic diseases found meaning through the following items: (1) surrender to God, (2) divine destiny, (3) care until death, (4) guarantee for health finance, (5) role replacement, and (6) observing the development of children and grandchildren. Conclusion: Elderly individuals with chronic diseases can obtained positive meaning in life through family support. Families are thus expected to facilitate the development of meaning in the lives of elderly individuals with chronic diseases to help them fulfill their spiritual needs.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"50 1","pages":"6"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85166578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Fucose is a deoxyhexose sugar. While the biological roles of L-fucose remain unclear, the sugar is known to accelerate the malignant potential of cancer cells. Therefore, this study aimed to evaluate the viability pattern of human cancer and normal cell lines treated with fucose. Methods: The human gingival fibroblast (HGF-1), colorectal adenocarcinoma (HT-29) and skin malignant melanoma (A375) cell lines were cultured and treated with fucose at three concentrations of 1, 5, and 10 mg/ml. Cell viability was then measured using (3-(4, 5-dimethylthiazolyl-2)-2, 5diphenyltetrazolium bromide (MTT) assay. The data were analyzed using Statistical Package for the Social Sciences software. Results: The percentage of HGF-1 cell viability showed a rapid decline after day 1 of treatment. HT-29 and A375 were capable of surviving treatment with high fucose concentrations. The data were highly significant at p < 0.001. Conclusion: Whereas a high concentration of fucose is toxic to the HGF-1 cell line, the HT-29 and A375 cell lines could potentially adapt to this condition. Downor upregulation of certain molecules that could induce or inhibit cell death may explain such adaptation. Further testing of upand downregulated molecules should be conducted in future work.
背景:焦糖是一种脱氧己糖。虽然L-病灶的生物学作用尚不清楚，但已知这种糖可以加速癌细胞的恶性潜能。因此，本研究旨在评估人类癌细胞和正常细胞系在聚焦作用下的生存模式。方法:培养人牙龈成纤维细胞(HGF-1)、结直肠腺癌(HT-29)和皮肤恶性黑色素瘤(A375)细胞系，并以1、5、10 mg/ml三种浓度进行聚焦处理。然后用(3-(4,5 -二甲基噻唑-2)- 2,5二苯基溴化四唑(MTT)法测定细胞活力。使用Statistical Package for Social Sciences软件对数据进行分析。结果:治疗第1天HGF-1细胞存活率迅速下降。HT-29和A375在高聚焦浓度下均能存活。数据高度显著，p < 0.001。结论:高浓度的聚焦对HGF-1细胞系是有毒的，而HT-29和A375细胞系可能适应这种情况。可以诱导或抑制细胞死亡的某些分子的下调或上调可以解释这种适应。在今后的工作中，需要对上调和下调的分子进行进一步的检测。
{"title":"Effects of L-fucose supplementation on the viability of cancer cell lines","authors":"Muhammad Alif Mazlan, A. M. Yusof, M. Isa","doi":"10.7454/msk.v24i2.1185","DOIUrl":"https://doi.org/10.7454/msk.v24i2.1185","url":null,"abstract":"Background: Fucose is a deoxyhexose sugar. While the biological roles of L-fucose remain unclear, the sugar is known to accelerate the malignant potential of cancer cells. Therefore, this study aimed to evaluate the viability pattern of human cancer and normal cell lines treated with fucose. Methods: The human gingival fibroblast (HGF-1), colorectal adenocarcinoma (HT-29) and skin malignant melanoma (A375) cell lines were cultured and treated with fucose at three concentrations of 1, 5, and 10 mg/ml. Cell viability was then measured using (3-(4, 5-dimethylthiazolyl-2)-2, 5diphenyltetrazolium bromide (MTT) assay. The data were analyzed using Statistical Package for the Social Sciences software. Results: The percentage of HGF-1 cell viability showed a rapid decline after day 1 of treatment. HT-29 and A375 were capable of surviving treatment with high fucose concentrations. The data were highly significant at p < 0.001. Conclusion: Whereas a high concentration of fucose is toxic to the HGF-1 cell line, the HT-29 and A375 cell lines could potentially adapt to this condition. Downor upregulation of certain molecules that could induce or inhibit cell death may explain such adaptation. Further testing of upand downregulated molecules should be conducted in future work.","PeriodicalId":51994,"journal":{"name":"Makara Journal of Health Research","volume":"337 1","pages":"1"},"PeriodicalIF":0.4,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83468079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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