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Comparison of Postoperative Analgesic Effect of Magnesium Sulfate and Gabapentin in Patients Undergoing Laparoscopic Cholecystectomy 硫酸镁与加巴喷丁对腹腔镜胆囊切除术后镇痛效果的比较
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/ajcm.28.3.139
Bita Barghi, Elahe Shakibi, Somayae Abdollahi Sabet, V. Rashtchi
Background and Objective: Considering the importance of pain management using effective medicines, the present study aimed to compare the analgesic effect of magnesium sulfate and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy. Materials and Methods: The present randomized clinical trial study was conducted on patients undergoing laparoscopic cholecystectomy in the operating room of Ayatollah Mousavi Hospital in Zanjan in 2019. The patients were assigned to three groups of 30 using the block randomization method. One group received 50 mg/kg of magnesium sulfate in 100 ml of normal saline within 1 h during the operation, the second group received 600 mg of gabapentin capsule 1 h before the operation, and the third group did not receive any additional medicines. The overall opioid dose, the time of the first analgesic request, and the Visual Analogue Scale (VAS ), 6, 12, 18, and 24 h postoperatively were compared in the three groups using repeated measures of ANOVA. Results: Based on the results, there was not a significant difference among the three groups in terms of gender and age (P>0.05). Moreover, the three groups t significantly differ in pain and drug dose received (P<0.001). The results of the Tukey post hoc test demonstrated that the pain and drug dose received in the control group was significantly higher than those in both intervention groups (P<0.001). Nonetheless, this difference between the two groups of magnesium sulfate and gabapentin was not statistically significant (P>0.05). Conclusion: As evidenced by the obtained results, in patients undergoing laparoscopic cholecystectomy, gabapentin and magnesium sulfate significantly reduced pain intensity and the need to use drugs; however, there was no significant difference between the two drugs.
背景与目的:考虑到使用有效药物进行疼痛管理的重要性,本研究旨在比较硫酸镁和加巴喷丁对腹腔镜胆囊切除术后疼痛的镇痛作用。材料和方法:本随机临床试验研究于2019年在赞詹Ayatollah Mousavi医院手术室对接受腹腔镜胆囊切除术的患者进行。采用分组随机化方法将患者分为三组,每组30人。一组在手术期间1小时内接受50mg/kg硫酸镁在100ml生理盐水中的溶液,第二组在手术前1小时接受600mg加巴喷丁胶囊,第三组不接受任何额外的药物。使用ANOVA重复测量,比较三组患者术后6、12、18和24小时的阿片类药物总剂量、首次镇痛请求时间和视觉模拟量表(VAS)。结果:三组患者性别、年龄差异无统计学意义(P>0.05),疼痛和用药剂量差异有统计学意义(P0.05),加巴喷丁和硫酸镁显著降低了疼痛强度和用药需求;然而,两种药物之间没有显著差异。
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引用次数: 1
Evaluation of the Relationship between Hematological Indices and Cardiovascular Events in Isfahan Cohort Study Isfahan队列研究中血液学指标与心血管事件关系的评价
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/ajcm.28.3.151
Atieh Jafari, A. Soleimani, Masoumeh Sadeghi, H. Roohafza, M. Talaei, Minoo Dianatkhah, N. Sarrafzadegan
Background and Objective: Cardiovascular Disease (CVD) is the leading cause of death in developing countries. Inflammation significantly contributes to the process of atherosclerosis. Therefore, evaluating White Blood Cells (WBC) and platelet counts as markers of inflammatory as well as hematocrit as a marker of blood viscosity may predict coronary events. The present study aimed to evaluate the relationship between hematological indices and the incidence of cardiovascular events. Materials and Methods: This study was based on the results of the Isfahan Cohort Study (ICS) which was a long-term, population-based study of 6504 adults over the age of 35 years with no history of CVD who were followed up for any incidence of CVD from 2001 to 2015. Basic levels of hematological indices were measured by entering the study. Results: About 49.5% of the population were male. The mean age of the population and individuals with CVD were about 51 and 57.6 years, respectively. Significant relationships were observed between systolic and diastolic blood pressures, fasting blood glucose, triglyceride, cholesterol, Low-Density Lipoprotein (LDL) levels, and waist circumference with the incidence of cardiovascular events (P<0.001 for all). Hematocrit, hemoglobin, RBC, and WBC measures were significantly associated with the incidence of cardiovascular events (P=0.002 for all). There was no significant relationship between platelet levels and the incidence of cardiovascular events. Conclusion: Hematological indices including WBC and RBC counts as well as hemoglobin and hematocrit levels can predict the incidence of cardiovascular events.
背景与目的:心血管疾病(CVD)是发展中国家的主要死亡原因。炎症在动脉粥样硬化过程中起着重要作用。因此,评估白细胞(WBC)和血小板计数作为炎症的标志,以及红细胞压积作为血液粘度的标志,可以预测冠状动脉事件。本研究旨在评价血液学指标与心血管事件发生率的关系。材料和方法:本研究基于Isfahan队列研究(ICS)的结果,这是一项长期的、基于人群的研究,6504名年龄在35岁以上、无心血管疾病病史的成年人在2001年至2015年期间接受了心血管疾病发病率的随访。进入研究时测量血液学指标的基本水平。结果:男性占49.5%。人群和CVD患者的平均年龄分别为51岁和57.6岁。收缩压和舒张压、空腹血糖、甘油三酯、胆固醇、低密度脂蛋白(LDL)水平和腰围与心血管事件发生率之间存在显著关系(均P<0.001)。红细胞压积、血红蛋白、红细胞和白细胞测量与心血管事件发生率显著相关(P=0.002)。血小板水平与心血管事件发生率无显著相关性。结论:血液学指标包括白细胞和红细胞计数以及血红蛋白和红细胞压积水平可以预测心血管事件的发生。
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引用次数: 0
Evaluation of Medication Adherence and its Related Factors among Type 2 Diabetic Patients 2型糖尿病患者药物依从性评价及其相关因素
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/ajcm.28.3.158
Sepideh Khanjani Movaghar, S. Khazaei, S. Borzouei
Background and Objective: Diabetes is the most common chronic metabolic disease in the world and one of its control principles is the patient's adherence to the physician's treatment recommendations. This study aimed to determine the adherence to medication treatment and related factors in type 2 diabetic patients referring to the Diabetes Clinic of Shahid Beheshti Hospital, Hamadan, Iran, in 2020. Materials and Methods: The present cross-sectional study was conducted on 284 patients with type 2 diabetes referring to the Diabetes Clinic of Shahid Beheshti Hospital. The data collection tool was a researcher-made questionnaire whose validity and reliability were confirmed in a pilot study. Data were analyzed in Stata software (version 11) at the significance level of 0.05. Results: Most of the patients were women (64.08%) and urban dwellers (79.08%). The mean age of the patients was obtained at 54.78 years, and 47.89% of the patients had poor medication adherence. Patients' medication adherence showed a statistically significant relationship with gender, marital status, education, physician's respectful behavior, respect for patient privacy, physician skill, the satisfaction of the physician, a history of other diseases, and a history of hypertension (P<0.05). Conclusion: It was revealed the adherence was in patients with type2 diabetes. In this study, the identified causes associated with poor medication adherence included factors related to the patient, care team and health system, treatment, and disease status. of Medication Adherence and its Related Factors among 2 Patients.
背景和目的:糖尿病是世界上最常见的慢性代谢性疾病,其控制原则之一是患者遵守医生的治疗建议。本研究旨在确定2020年在伊朗哈马丹Shahid Beheshti医院糖尿病诊所就诊的2型糖尿病患者对药物治疗的依从性和相关因素。材料和方法:本横断面研究是在Shahid Beheshti医院糖尿病门诊对284名2型糖尿病患者进行的。数据收集工具是研究人员制作的问卷,其有效性和可靠性在试点研究中得到了证实。数据在Stata软件(版本11)中以0.05的显著性水平进行分析。结果:大多数患者为女性(64.08%)和城市居民(79.08%),患者的平均年龄为54.78岁,47.89%的患者药物依从性差。患者的药物依从性与性别、婚姻状况、教育程度、医生尊重行为、尊重患者隐私、医生技能、医生满意度、其他疾病史和高血压史有统计学意义(P<0.05)。在这项研究中,已确定的与药物依从性差相关的原因包括与患者、护理团队和卫生系统、治疗和疾病状态相关的因素。2例患者药物依从性及其相关因素分析。
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引用次数: 1
Investigation of the Persistence and Effects of Core Stability Exercises on Disability and Dynamic Balance in Women with Non-Specific Chronic Low Back Pain 非特异性慢性腰痛患者核心稳定性锻炼的持续性及其对残疾和动态平衡影响的研究
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/ajcm.28.3.166
H. Shahrokhi, Mohammad Fallah Mohammadi, Zahra Nabizade
Background and Objective: Low back pain is one of the most common musculoskeletal disorders. Exercise therapy is one of the most common treatments for low back pain. The aim of the present study was to investigate the effects of 6-week core stability exercises on disability and dynamic balance in women with non-specific chronic low back pain. Materials and Methods: This controlled clinical trial with pre-test, post-test, and follow-up design was performed on 24 women with non-specific chronic low back pain within the age range of 30-50 years. They were randomly divided into experimental and control groups. Oswestry Disability Index and Biodex stability system were used to assess disability and dynamic balance indices (overall, anterior-posterior, medial-lateral indices, and limit of stability), respectively. Core stability exercise sessions were held for the experimental group three times per week for 6 weeks and the control group received no intervention. Data were analyzed by using mixed analysis of variance repeated measure at a significance level of P ≤ 0.05. Results: The results showed that core stability exercises led to a significant increase in the limit of stability and a significant decrease in disability and overall, anterior-posterior, and medial-lateral dynamic postural stability indexes (P≤0.05). Moreover, significant differences were observed between the two groups regarding all outcome measures after the intervention. Besides, there was a significant difference between pre-test and follow-up stages in terms of outcome measures (P≤0.05). Conclusion: According to findings, the core stability exercises resulted in considerable improvements in disability and balance in women with nonspecific chronic low back pain.
背景与目的:腰痛是最常见的肌肉骨骼疾病之一。运动疗法是治疗腰痛最常见的方法之一。本研究的目的是研究6周的核心稳定性训练对非特异性慢性腰痛妇女残疾和动态平衡的影响。材料和方法:这项对照临床试验包括试验前、试验后和随访设计,对24名30-50岁的非特异性慢性腰痛妇女进行了研究。他们被随机分为实验组和对照组。Oswestry残疾指数和Biodex稳定性系统分别用于评估残疾和动态平衡指数(整体、前后、内侧-外侧指数和稳定性极限)。实验组每周进行三次核心稳定性训练,持续6周,对照组不接受干预。数据采用方差重复测量的混合分析进行分析,显著性水平为P≤0.05。结果:核心稳定性训练使稳定性极限显著提高,残疾和整体、前后和内外侧动态姿势稳定性指数显著降低(P≤0.05)。此外,干预后两组在所有结果指标上存在显著差异。此外,在结果测量方面,测试前和随访阶段之间存在显著差异(P≤0.05)。结论:根据研究结果,核心稳定性训练显著改善了非特异性慢性腰痛妇女的残疾和平衡。
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引用次数: 0
Association of Polymorphisms of F2 (rs3136520) and PAI-1(rs6090) Genes with Recurrent Pregnancy Loss in Iranian Azeri Women F2 (rs3136520)和PAI-1(rs6090)基因多态性与伊朗阿塞拜疆妇女复发性妊娠丢失的关系
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.118
M. Yousefian, S. Angaji, E. Siasi, S. Rahmani, Shamci Abbasalizadeh Khiaban
Background and Objective: The mutation of F2 and PAI-1 genes can cause thrombophilia in women. The present study aimed to assess the relationship of recurrent pregnancy loss (RPL) with rs3136520 in F2 and rs6090 in PAI-1. Materials and Methods: This case-control study was conducted on 120 women with idiopathic RPL as case group and 120 healthy women without any history of infertility or abortion with at least one healthy child as the control group. These subjects were referred to a private genetic lab by a gynecologist. Both polymorphisms were studied using the amplificationrefractory mutation system-polymerase chain reaction approach, and the obtained data were analyzed in SPSS software (version 26) using the chisquared test (P˂0.05). Results: In the multiplicative model, there was a significant association between rs6090 and RPL (OR=0.222; 95%CI=0.082-0.599); nonetheless, no relationship was detected between rs3136520 and RPL (OR=1, 95%CI=0.488-2.049). Moreover, according to additive model, there was no association between rs3136520 and RPL; however, there was a significant relationship between AG genotype in rs6090 and RPL (OR=0.245; 95%
背景与目的:F2和PAI-1基因突变可引起女性血栓形成倾向。本研究旨在评估复发性妊娠损失(RPL)与F2中rs3136520和PAI-1中rs6090的关系。材料和方法:本病例对照研究以120名特发性RPL妇女为病例组,120名无不孕或流产史的健康妇女为对照组,至少有一名健康儿童。这些受试者被一位妇科医生转介到一家私人基因实验室。结果:在乘法模型中,rs6090与RPL之间存在显著相关性(OR=0.222;95%CI=0.082-0.599);但rs3136520与RPL无相关性(OR=1,95%CI=0.488-2.049)。此外,根据加性模型,rs313652与RPL之间无相关性;然而,rs6090中的AG基因型与RPL之间存在显著关系(OR=0.245;95%
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引用次数: 0
Malrotated Ectopic Kidney with Hydronephrosis: A Case Report 异位异位肾并肾积水1例报告
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.134
A. Salehi, H. Salehi, E. Khanlarzadeh
Background and Objective: Congenital renal anomalies cover a significant portion of abnormalities, which may be due to variations in number, position, shape, and size of the kidney(s). Most studies are based on structural, local, and vascular abnormalities, while few of them, to the best of our knowledge, were conducted on abnormal renal rotation (renal
背景和目的:先天性肾脏异常涵盖了很大一部分异常,这可能是由于肾脏的数量、位置、形状和大小的变化。大多数研究都是基于结构、局部和血管异常,而据我们所知,很少有研究是针对异常肾旋转(肾
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引用次数: 0
Prediction of Generalized Anxiety in Neurotic People Based on Resilience 基于弹性的神经症患者广泛性焦虑预测
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.87
T. Sepahvand, M. Bayat
Background and Objective: Anxiety is an important aspect of neuroticism and may be related to potential mechanisms such as resilience. This study aimed to predict generalized anxiety in neurotic people based on resilience. Materials and Methods: This was a correlational forecasting study. The study population consisted of students of Arak University, Arak, Iran, in 2019, from whom a sample of 300 individuals was selected using the convenience sampling method. The study tools for data collection included the Neuroticism scale of NEO Five-Factor Inventory, Generalized Anxiety Disorder Scale-7, and Connor-Davidson Resilience Scale. Eventually, 70 participants who obtained high scores on the Neuroticism Scale (score 24 and over) were studied. Results: Simultaneous multiple regression analysis showed that resilience components predicted about 31% of the variance of generalized anxiety in neurotic people (F=5.846, P< 0.001). It was revealed that the components of notion of personal competence, high standards, and tenacity (with a Beta coefficient of -0.446), and positive acceptance of change and secure relationships (with a Beta coefficient of -0.439) had a negative and significant role in this prediction. However, other components did not have a significant role in this regard. Conclusion: Based on the obtained results, resilience in accordance with the components of notion of personal competence and positive acceptance of change is an important variable for the prediction of generalized anxiety in neurotic people that should be seriously considered and strengthened to
背景与目的:焦虑是神经质的一个重要方面,可能与心理弹性等潜在机制有关。本研究旨在基于弹性预测神经症患者的广泛性焦虑。材料与方法:本研究为相关预测研究。研究人群由2019年伊朗阿拉克阿拉克大学的学生组成,使用方便抽样方法从中选择了300人的样本。数据收集的研究工具包括NEO五因素量表神经质量表、广泛性焦虑障碍量表-7和Connor-Davidson弹性量表。最终,70名在神经质量表上获得高分(24分及以上)的参与者被研究。结果:同时多元回归分析显示,弹性成分对神经症患者广泛性焦虑方差的预测率约为31% (F=5.846, P< 0.001)。结果显示,个人能力观念、高标准观念、坚韧观念(Beta系数为-0.446)、积极接受变化和安全关系(Beta系数为-0.439)对该预测具有显著负向作用。但是,其他组成部分在这方面没有发挥重要作用。结论:根据所得结果,与个人能力观念和积极接受变化相一致的弹性是预测神经症患者广泛性焦虑的重要变量,应予以重视和加强
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引用次数: 0
Cephalometric Evaluation of Facial Soft Tissue Thickness in Patients under Orthodontic Treatment with Class I Occlusion and Vertical Growth Pattern Regarding Age and Gender 正畸I类咬合垂直生长模式患者面部软组织厚度的头颅测量与年龄、性别的关系
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.104
Faezeh Yousefi, Faezeh Oliaii, Vahid Mollabashi, M. Farhadian
Background and Objective: Cosmetic facial surgery and soft tissue are among the main reasons for orthodontic treatment and referral to dentistry. This study aimed to conduct a cephalometric evaluation of facial soft tissue thickness in patients candidates for orthodontic treatment in terms of age and gender referring to School of Dentistry, Hamadan, Iran. Materials and Methods: This cross-sectional study investigated the cephalometric radiography of 200 patients (100 males and 100 females) with skeletal class I (ANB 1-4) and vertical growth patterns. The patients were then divided into four age groups of 10-15, 15-20, 20-25, and 25-30 years with an equal number of males and females. Following that, the soft tissues in the glabella frontal, nose, subnasal, upper lip, lower lip, and chin were measured. The data were analyzed in SPSS software (version 21) through the t-test and ANOVA. Results: In general, the soft tissue thickness of the nose increased with age. Regarding gender (regardless of age), the males had thicker upper and lower lips, as well as subnasal, compared to females. Considering the simultaneous assessment of age and gender, the males had thicker soft tissue in the lower and upper lips, as well as subnasal areas. Conclusion: With an increase in age, only the soft tissue of the nose increased significantly. Moreover, in the same age groups, the males had thicker lower and upper lips.
背景和目的:面部美容手术和软组织是正畸治疗和转诊牙科的主要原因。本研究旨在根据年龄和性别对伊朗哈马丹牙科学院的正畸治疗候选患者的面部软组织厚度进行头影测量评估。材料和方法:这项横断面研究调查了200名骨骼I级(ANB 1-4)和垂直生长模式患者(100名男性和100名女性)的头影测量放射学。然后将患者分为10-15岁、15-20岁、20-25岁和25-30岁四个年龄组,男女人数相等。然后,测量额玻璃、鼻、下唇、上唇、下唇和下巴的软组织。数据在SPSS软件(版本21)中通过t检验和方差分析进行分析。结果:总的来说,鼻子的软组织厚度随着年龄的增长而增加。关于性别(不分年龄),与女性相比,男性的上唇和下唇以及下唇以下。考虑到对年龄和性别的同时评估,男性下唇和上唇以及下唇以下区域的软组织较厚。结论:随着年龄的增长,只有鼻部软组织明显增加。此外,在同一年龄组中,男性的下唇和上唇较厚。
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引用次数: 0
Relationship between Computed Tompgraphy Pulmonary Angiography Findings and Clinical Findings Based on Wells Score in Acute Pulmonary Thromboembolism 急性肺血栓栓塞的ct肺血管造影表现与临床表现的关系
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.71
Seyed Kamaledin Hadei, L. Molani, Zohreh Kahramfar, Y. Mohammadi
Background and Objective: Acute pulmonary thromboembolism is an emergency disease that can lead to mortality if not diagnosed on time. Proper triage of patients based on clinical findings and the Wells Score will have a significant impact on the medical team's decision-making and patient management. Materials and Methods: This descriptive cross-sectional study was conducted on 300 patients selected by the census sampling method. The patients were suspected of acute pulmonary thromboembolism referring to Farshchian Heart Hospital in Hamadan, Iran, within October 2017-March 2020. The cases considered a candidate for computed tomography (CT) pulmonary angiography were selected and compared regarding CT pulmonary angiography results and the risk of embolism based on Wells
背景与目的:急性肺血栓栓塞症是一种急诊疾病,如果不及时诊断可能导致死亡。根据临床结果和威尔斯评分对患者进行适当的分诊将对医疗团队的决策和患者管理产生重大影响。材料和方法:这项描述性横断面研究采用普查抽样法对300名患者进行。2017年10月至2020年3月,这些患者在伊朗哈马丹的Farshchian心脏病医院被怀疑患有急性肺血栓栓塞症。选择被认为是计算机断层扫描(CT)肺血管造影术候选者的病例,并根据Wells的CT肺血管造影术结果和栓塞风险进行比较
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引用次数: 0
Effectivenes of Acceptance-Commitment Therapy on the Resillience and Psycological Well-being of Female Patients with Multiple Sclerosis in Hamadan, Iran 接受-承诺疗法对伊朗哈马丹女性多发性硬化症患者心理健康和恢复力的影响
Q4 Medicine Pub Date : 2021-09-01 DOI: 10.52547/ajcm.28.2.126
Shahin Tavakoli Saleh, M. Ebrahimi
Background and Objective: Multiple Sclerosis (MS) is a chronic and progressive disease of the central nervous system that severely affects the individuals' physical health and psychological well-being. This study aimed to investigate the effect of acceptance-commitment therapy on the resilience and psychological well-being of women with MS in Hamadan Province, Iran. Materials and Methods: This quasi-experimental study was conducted based on a pretest-posttest design with a control group. The statistical population consisted of women with MS in Hamadan, Iran. In total, 40 women were randomly selected and randomly divided into two groups of intervention and control (20 cases per group). The intervention group participated in eight 90-min sessions of virtual acceptance-commitment group therapy (one session per week). On the other hand, the control group received no intervention. The resilience and psychological well-being of the both groups were measured before and after the intervention using ConnorDavidson Resilience Scale and Ryff Scale of Psychological Well-Being, followed by analysis of covariance. Regression analysis and Pearson correlation coefficient were used after ensuring that the statistical assumptions were met. Results: The mean values of resilience in the intervention and control groups at pretest were obtained at 43.33±3.16 and 43.80±3.53 (P>0.05), and the corresponding values were determined at 53.13±2.85 and 43.47±4.05 (P<0.05) at the posttest, respectively. Furthermore, the mean values of the psychological well-being in the intervention and control groups at pretest were calculated at 119.38±7.59 and 94.07±7.36 (P>0.05), and the corresponding values were 163.67±10.96 and 94.97±9.63 (P<0.05) at the posttest, respectively. This indicated a significant difference between the intervention and control groups. Conclusion: The results showed that the acceptance-commitment therapy increased the resilience and psychological well-being of the patients with MS.
背景与目的:多发性硬化症(MS)是一种慢性进行性中枢神经系统疾病,严重影响个体的身体健康和心理健康。本研究旨在调查接受承诺疗法对伊朗哈马丹省多发性硬化症妇女恢复力和心理健康的影响。材料和方法:这项准实验研究是在前测后测设计的基础上与对照组进行的。统计人群包括伊朗哈马丹的多发性硬化症妇女。总共有40名女性被随机选择,并随机分为干预组和对照组(每组20例)。干预组参加了八次90分钟的虚拟接受承诺组治疗(每周一次)。另一方面,对照组未接受干预。采用ConnorDavidson复原力量表和Ryff心理幸福感量表测量干预前后两组患者的复原力和心理幸福感,并进行协方差分析。在确保满足统计假设后,使用回归分析和Pearson相关系数。结果:干预组和对照组在前测时的恢复力平均值分别为43.33±3.16和43.80±3.53(P>0.05),对应值分别为53.13±2.85和43.47±4.05(P0.05),后测时的对应值分别是163.67±10.96和94.97±9.63(P<0.05)。这表明干预组和对照组之间存在显著差异。结论:接受承诺治疗能提高MS患者的恢复力和心理健康。
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引用次数: 2
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