Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and its A receptor in dental lamina in different stages of tooth development. Materials and Methods: This cross-sectional study included 33 fetal samples that were divided into three groups regarding gestational age. All samples were then stained by immunohistochemistry. Subsequently, the analysis was conducted in SPSS software (version 20) through the two-way ANOVA and Tukey's tests to examine the differences between the variables. A p-value less than 0.05 was considered statistically significant. Results: There was a significant difference between the gestational age and the expression level of endothelin-1 in dental lamina (P<0.001). In addition, a significant relationship was observed between age and anatomic area (P<0.001). There was also a significant difference between the gestational age and the expression level of endothelin-1 receptor (ETAR) in dental lamina (P<0.001). A significant association was found between gestational age and anatomic area (P<0.001). Conclusion: The expression levels of endothelin-1 and its receptor (ETAR) in each jaw were higher in anterior dental lamina, compared to posterior dental lamina. These results may confirm the role of endothelin-1 and its receptor in cell proliferation, differentiation of dental lamina, and calcium ion transport during tooth development.
{"title":"Evaluation of the Expression Levels of Endothelin-1 and its Receptor (ETAR) in Dental Lamina during Different Stages of Development of Human Fetal Teeth","authors":"S. Irani, S. Alimohammadi, Tahmineh Najafian","doi":"10.52547/ajcm.28.2.79","DOIUrl":"https://doi.org/10.52547/ajcm.28.2.79","url":null,"abstract":"Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and its A receptor in dental lamina in different stages of tooth development. Materials and Methods: This cross-sectional study included 33 fetal samples that were divided into three groups regarding gestational age. All samples were then stained by immunohistochemistry. Subsequently, the analysis was conducted in SPSS software (version 20) through the two-way ANOVA and Tukey's tests to examine the differences between the variables. A p-value less than 0.05 was considered statistically significant. Results: There was a significant difference between the gestational age and the expression level of endothelin-1 in dental lamina (P<0.001). In addition, a significant relationship was observed between age and anatomic area (P<0.001). There was also a significant difference between the gestational age and the expression level of endothelin-1 receptor (ETAR) in dental lamina (P<0.001). A significant association was found between gestational age and anatomic area (P<0.001). Conclusion: The expression levels of endothelin-1 and its receptor (ETAR) in each jaw were higher in anterior dental lamina, compared to posterior dental lamina. These results may confirm the role of endothelin-1 and its receptor in cell proliferation, differentiation of dental lamina, and calcium ion transport during tooth development.","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43018398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kermanian, Neda Esmail Khani, M. Mokhtaree, A. Sayadi
Background and Objective: Suicide occurs due to a variety of causes, from heredity and biological factors to environmental factors. The present study aimed to evaluate the serum levels of vitamin D, ferritin, and hemoglobin in patients with attempted suicide referring to hospitals and compare them with the control group. Materials and Methods: A comparison was made between the serum levels of vitamin D, ferritin, and hemoglobin of 60 suicidal patients referring to Ali ibn Abitaleb hospital of Rafsanjan from March to september 2020 and those of 60 relatives of selected patients with no history of suicide. The control group completed the Beck Suicide Thought Questionnaire (BSTQ). Chisquare, ANOVA, independent t-test, Mann-Whitney U test, and KruskalWallis statistical tests were used to analyze the data. Results: The serum level of vitamin D in Patient with attempted suicide was lower, compared to that in controls (P=0.025). Among the age group of 1535 years, serum levels of vitamin D were lower than those in the control group (P=0.039). Moreover, serum ferritin level in the attempted suicide group was lower than that in the control group (P=0.003). Serum ferritin level was significantly lower among the suidide attempters aged 15-15 years (P= 0.003), men with attempted suicide (P= 0.003) and suicidal women (P= 0.045), as compared to the control group. Conclusion: As demonstratedd by the results of the present study, vitamin D deficiency and anemia can be two major risk factors for suicide. Therefore, it is necessary to identify and treat these deficiencies in people with psychological disorders, such as depression.
背景与目的：自杀的发生有多种原因，从遗传、生物因素到环境因素。本研究旨在评估医院就诊的自杀未遂患者的血清维生素D、铁蛋白和血红蛋白水平，并将其与对照组进行比较。材料和方法：比较2020年3月至9月在拉夫桑詹Ali ibn Abitaleb医院就诊的60名自杀患者与60名无自杀史患者亲属的血清维生素D、铁蛋白和血红蛋白水平。对照组完成贝克自杀思想调查表（BSTQ）。Chisquare、ANOVA、独立t检验、Mann-Whitney U检验和KruskalWallis统计检验用于分析数据。结果：自杀未遂患者血清维生素D水平低于对照组（P=0.025），1535岁年龄组血清维生素D含量低于对照组，自杀未遂组血清铁蛋白水平低于对照组（P=0.003），15～15岁自杀未遂者（P=0.0003）、自杀未遂男性（P=0.003）和自杀女性（P=0.045）血清铁蛋白含量显著低于对照组。结论：本研究结果表明，维生素D缺乏和贫血可能是自杀的两个主要危险因素。因此，有必要识别和治疗抑郁症等心理障碍患者的这些缺陷。
{"title":"Evaluation of Serum Levels of Vitamin D, Ferritin, and Hemoglobin in Suicide Attempters Admitted or Outpatients Referred to Hospitals and Psychiatric Clinics of Rafsanjan University of Medical Sciences","authors":"A. Kermanian, Neda Esmail Khani, M. Mokhtaree, A. Sayadi","doi":"10.52547/ajcm.28.1.36","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.36","url":null,"abstract":"Background and Objective: Suicide occurs due to a variety of causes, from heredity and biological factors to environmental factors. The present study aimed to evaluate the serum levels of vitamin D, ferritin, and hemoglobin in patients with attempted suicide referring to hospitals and compare them with the control group. Materials and Methods: A comparison was made between the serum levels of vitamin D, ferritin, and hemoglobin of 60 suicidal patients referring to Ali ibn Abitaleb hospital of Rafsanjan from March to september 2020 and those of 60 relatives of selected patients with no history of suicide. The control group completed the Beck Suicide Thought Questionnaire (BSTQ). Chisquare, ANOVA, independent t-test, Mann-Whitney U test, and KruskalWallis statistical tests were used to analyze the data. Results: The serum level of vitamin D in Patient with attempted suicide was lower, compared to that in controls (P=0.025). Among the age group of 1535 years, serum levels of vitamin D were lower than those in the control group (P=0.039). Moreover, serum ferritin level in the attempted suicide group was lower than that in the control group (P=0.003). Serum ferritin level was significantly lower among the suidide attempters aged 15-15 years (P= 0.003), men with attempted suicide (P= 0.003) and suicidal women (P= 0.045), as compared to the control group. Conclusion: As demonstratedd by the results of the present study, vitamin D deficiency and anemia can be two major risk factors for suicide. Therefore, it is necessary to identify and treat these deficiencies in people with psychological disorders, such as depression.","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43204676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objective: Attention Deficit Hyperactivity Disorder (ADHD) is a common neuropsychological disorder among children that might lead to disruption of daily activities. Therefore, this study aimed to determine the effects of pyridoxine on the treatment and reduction of symptoms severity in children with ADHD under Ritalin treatment. Materials and Methods: This clinical trial included a total of 50 children with ADHD in the age range of 5-12 years who were referred to Emam clinic of Children’s Neurology and Be’sat Hospital, Hamedan, Iran, and were selected using a convenience sampling approach. The participants were divided into two similar treatment groups. One group only received Ritalin as the treatment and the second group received Pyridoxine and Ritalin together. The change in the severity of the symptoms was analyzed using Conners Rating Scale. Results: The patients in the two treatment groups were identical in terms of age and gender. The mean score of disease severity in both groups reduced up to 23.92 and 32.12 units, respectively, compared to those before intervention (P<0.001). In addition, there was a statistically significant difference between the severity of symptoms before and after intervention in both groups following the intervention (the mean scores of the severity of symptoms were obtained at 65.09 and 54.00, respectively) in children with
{"title":"Effects of Pyridoxine on Improving Attention Deficit Hyperactivity Disorder Symptoms among Children under Ritalin Treatment","authors":"Afshin Fayazi, Shahin Seifodin, A. Moradi","doi":"10.29252/AJCM.28.1.5","DOIUrl":"https://doi.org/10.29252/AJCM.28.1.5","url":null,"abstract":"Background and Objective: Attention Deficit Hyperactivity Disorder (ADHD) is a common neuropsychological disorder among children that might lead to disruption of daily activities. Therefore, this study aimed to determine the effects of pyridoxine on the treatment and reduction of symptoms severity in children with ADHD under Ritalin treatment. Materials and Methods: This clinical trial included a total of 50 children with ADHD in the age range of 5-12 years who were referred to Emam clinic of Children’s Neurology and Be’sat Hospital, Hamedan, Iran, and were selected using a convenience sampling approach. The participants were divided into two similar treatment groups. One group only received Ritalin as the treatment and the second group received Pyridoxine and Ritalin together. The change in the severity of the symptoms was analyzed using Conners Rating Scale. Results: The patients in the two treatment groups were identical in terms of age and gender. The mean score of disease severity in both groups reduced up to 23.92 and 32.12 units, respectively, compared to those before intervention (P<0.001). In addition, there was a statistically significant difference between the severity of symptoms before and after intervention in both groups following the intervention (the mean scores of the severity of symptoms were obtained at 65.09 and 54.00, respectively) in children with","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48999193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Alipour, K. Khashei Varnamkhasti, Marzieh Eslami Moghaddam, Masumeh Panahi
Background: Giant congenital melanocytic nevus is caused by intrauterine somatic mutations in the genes involved in the mitogen-activated protein kinase pathway. It is a rare melanocytic lesion with a prevalence of 1 per 20,000 live births occurring at birth or shortly thereafter. Case Presentation: Here, we presented the case of a term male neonate with giant congenital melanocytic nevus. He was born to a 33-year-old mother. The initial pediatric examination revealed a skin mosaic pattern in his torso. The pigmented and rough skin of this area, along with several prominent wart-shaped lesions and demarcated borders, confirmed the giant congenital melanocytic nevus. Conclusion: Despite the rarity of this lesion, it is of great importance since it may associate with severe complications, such as malignant melanoma. Therefore, it is necessary to adopt appropriate medical management by recognizing the nature of the lesion.
{"title":"A Case Report of Giant Congenital Melanocytic Nevus","authors":"M. Alipour, K. Khashei Varnamkhasti, Marzieh Eslami Moghaddam, Masumeh Panahi","doi":"10.52547/ajcm.28.1.66","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.66","url":null,"abstract":"Background: Giant congenital melanocytic nevus is caused by intrauterine somatic mutations in the genes involved in the mitogen-activated protein kinase pathway. It is a rare melanocytic lesion with a prevalence of 1 per 20,000 live births occurring at birth or shortly thereafter. Case Presentation: Here, we presented the case of a term male neonate with giant congenital melanocytic nevus. He was born to a 33-year-old mother. The initial pediatric examination revealed a skin mosaic pattern in his torso. The pigmented and rough skin of this area, along with several prominent wart-shaped lesions and demarcated borders, confirmed the giant congenital melanocytic nevus. Conclusion: Despite the rarity of this lesion, it is of great importance since it may associate with severe complications, such as malignant melanoma. Therefore, it is necessary to adopt appropriate medical management by recognizing the nature of the lesion.","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48054709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sobhan, E. Khanlarzadeh, Mahrokh Moradi Rozbhani
Background and Objective: Seborrheic dermatitis is one of the most common inflammatory skin diseases that affect the sebaceous glands. Although the exact role of vitamin D in this disease is still not clearly understood, some studies have shown lower serum levels of vitamin D in seborrheic dermatitis patients. This study aimed to investigate the correlation between vitamin D deficiency and seborrheic dermatitis. Materials and Methods: This cross-sectional case-control study was conducted in Sina Hospital, Hamadan, Iran. The study sample included 39 seborrheic dermatitis patients (case group) and 39 healthy individuals (control group) who were matched in terms of gender and age. The groups were then compared regarding serum vitamin D level. Statistical analysis was performed in SPSS software (version 16.0; SPSS Inc.Chicago, IL). Results: There were no significant differences between the two groups in terms of age, gender, educational level, place of residence, and occupational status. The mean serum levels of vitamin D in the case and control groups were 11.82±5.56 and 21.38±6.79ng/ml, respectively (P=0.001). Furthermore, in the case and control groups, 18 (46.2%) and 1 (2.6%) individuals had vitamin D deficiency; 20 (51.3%) and 34 (87.2%) cases had inadequate vitamin D levels; and 1(2.6%) and 4 (10.3%) subjects had adequate levels of vitamin D, respectively. Therefore, the serum level of vitamin D was significantly lower in the case group, compared to the control group (P=0.001). Moreover, the serum level of vitamin D did not correlate with the duration and severity of seborrheic dermatitis disease (P>0.05). Conclusion: According to the findings of this study, patients with seborrheic dermatitis had lower serum vitamin D levels, compared to the general population, which may be related to the pathogenicity of the disease.
{"title":"Correlation between Vitamin D Deficiency and Seborrheic Dermatitis in Patients Referred to the Dermatology Clinic of Sina Hospital, Hamadan, Iran","authors":"M. Sobhan, E. Khanlarzadeh, Mahrokh Moradi Rozbhani","doi":"10.52547/ajcm.28.1.20","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.20","url":null,"abstract":"Background and Objective: Seborrheic dermatitis is one of the most common inflammatory skin diseases that affect the sebaceous glands. Although the exact role of vitamin D in this disease is still not clearly understood, some studies have shown lower serum levels of vitamin D in seborrheic dermatitis patients. This study aimed to investigate the correlation between vitamin D deficiency and seborrheic dermatitis. Materials and Methods: This cross-sectional case-control study was conducted in Sina Hospital, Hamadan, Iran. The study sample included 39 seborrheic dermatitis patients (case group) and 39 healthy individuals (control group) who were matched in terms of gender and age. The groups were then compared regarding serum vitamin D level. Statistical analysis was performed in SPSS software (version 16.0; SPSS Inc.Chicago, IL). Results: There were no significant differences between the two groups in terms of age, gender, educational level, place of residence, and occupational status. The mean serum levels of vitamin D in the case and control groups were 11.82±5.56 and 21.38±6.79ng/ml, respectively (P=0.001). Furthermore, in the case and control groups, 18 (46.2%) and 1 (2.6%) individuals had vitamin D deficiency; 20 (51.3%) and 34 (87.2%) cases had inadequate vitamin D levels; and 1(2.6%) and 4 (10.3%) subjects had adequate levels of vitamin D, respectively. Therefore, the serum level of vitamin D was significantly lower in the case group, compared to the control group (P=0.001). Moreover, the serum level of vitamin D did not correlate with the duration and severity of seborrheic dermatitis disease (P>0.05). Conclusion: According to the findings of this study, patients with seborrheic dermatitis had lower serum vitamin D levels, compared to the general population, which may be related to the pathogenicity of the disease.","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45769415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objective: Each type of cancer has its own histopathological findings that determine the type of treatment regimen and the course of the disease. The present study aimed to histopathologically determine the types of gynecological cancers in patients admitted to Baqiyatallah Hospital over a nine-year period. Materials and Methods: This retrospective study was conducted based on hospital data of patients who were admitted to Baqiyatallah Hospital and underwent any procedure, treatment, and diagnosis of gynecologic cancers during 2011-2019. Patients' information was extracted from hospital integrated archiving system. Results: A total of 404 patients were diagnosed with gynecological cancers between 2011 and 2019. Among these cancers, ovarian cancer with 212 (52.5%) patients was the most common gynecological cancer. Among patients with ovarian cancer, Serous Adenocarcinoma and Endometrioid Adenocarcinoma with 137 (64.6%) and 29 (13.7%) cases had the highest frequency of pathology, respectively. The mean (standard deviation) age of the patients with gynecological cancer was 55.88 (11.51) years. During the study period, there was a relatively increasing trend for ovarian cancer during 2011-19. Conclusion: ovarian cancer with Serous Adenocarcinoma was the most common cancer diagnosed in patients admitted to Baqiyatallah Hospital during 2011-19. The relatively increasing trend of this type of female genital cancers during this 9-year period and the observed age pattern highlight the importance of implementing timely screening and treatment programs.
{"title":"Histopathological Study of Gynecological Cancers in Patients Admitted to Baqiyatallah Hospital in Tehran during 2011-2019","authors":"S. Hashemi, M. Akbari, Z. Soleimani","doi":"10.52547/ajcm.28.1.42","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.42","url":null,"abstract":"Background and Objective: Each type of cancer has its own histopathological findings that determine the type of treatment regimen and the course of the disease. The present study aimed to histopathologically determine the types of gynecological cancers in patients admitted to Baqiyatallah Hospital over a nine-year period. Materials and Methods: This retrospective study was conducted based on hospital data of patients who were admitted to Baqiyatallah Hospital and underwent any procedure, treatment, and diagnosis of gynecologic cancers during 2011-2019. Patients' information was extracted from hospital integrated archiving system. Results: A total of 404 patients were diagnosed with gynecological cancers between 2011 and 2019. Among these cancers, ovarian cancer with 212 (52.5%) patients was the most common gynecological cancer. Among patients with ovarian cancer, Serous Adenocarcinoma and Endometrioid Adenocarcinoma with 137 (64.6%) and 29 (13.7%) cases had the highest frequency of pathology, respectively. The mean (standard deviation) age of the patients with gynecological cancer was 55.88 (11.51) years. During the study period, there was a relatively increasing trend for ovarian cancer during 2011-19. Conclusion: ovarian cancer with Serous Adenocarcinoma was the most common cancer diagnosed in patients admitted to Baqiyatallah Hospital during 2011-19. The relatively increasing trend of this type of female genital cancers during this 9-year period and the observed age pattern highlight the importance of implementing timely screening and treatment programs.","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46017223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamid Reza Ghasemi Basir, F. Keramat, A. Moradi, Z. Khani, A. Saadatmand
Background and Objective: The increased resistance of microorganisms to common antibiotics is one of the major therapeutic challenges for patients. The present study aimed to compare the antibiogram results of two types of antibiotic discs and validate them by the Epsilometer test (E-test) method on bacteria with high antibiotic resistance patterns. Materials and Methods: This descriptive-analytical study was performed by the census method on 176 patients admitted to different wards of Sina Hospital in Hamadan from March 2016 to March 2019. The patients entered the study with a positive culture result and underwent the antibiogram using two types of discs. Following that, validation was performed by the Etest method in cases with significant differences. Finally, the results were described and analyzed in SPSS software (version 16) at a 95% confidence
{"title":"Comparison of Antibiogram Results of Two Types of Antibiotic Discs and Validation by E.test Method on Bacteria with High Antibiotic Resistance Patterns","authors":"Hamid Reza Ghasemi Basir, F. Keramat, A. Moradi, Z. Khani, A. Saadatmand","doi":"10.52547/ajcm.28.1.59","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.59","url":null,"abstract":"Background and Objective: The increased resistance of microorganisms to common antibiotics is one of the major therapeutic challenges for patients. The present study aimed to compare the antibiogram results of two types of antibiotic discs and validate them by the Epsilometer test (E-test) method on bacteria with high antibiotic resistance patterns. Materials and Methods: This descriptive-analytical study was performed by the census method on 176 patients admitted to different wards of Sina Hospital in Hamadan from March 2016 to March 2019. The patients entered the study with a positive culture result and underwent the antibiogram using two types of discs. Following that, validation was performed by the Etest method in cases with significant differences. Finally, the results were described and analyzed in SPSS software (version 16) at a 95% confidence","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47516248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alireza Nikoonejad, Ali Shafizadeh Arjomandi, S. Dodangeh, A. Allami
Background and Objective: Coronavirus Disease 2019 (COVID-19) has caused the death of many people, mainly by causing respiratory failure. The method of quarantine for the control of this disease leads to deprivation of vitamin D3 production. In this regard, this study aimed to investigate the relationship between serum vitamin D3 level and risk of COVID-19. Materials and Methods: This case-control study was conducted in BouAli Sina Hospital in Qazvin, Iran in September 2020. The statistical population of the case group included patients with COVID-19 referred to this center, while the control group comprised non-COVID-19 patients who referred to the center. Vitamin D3 levels of the participants were assessed and the findings were recorded. The collected data were analyzed using statistical
{"title":"Comparison of Serum Level of Vitamin D3 in Covid-19 Patients and Non-Infected Individuals","authors":"Alireza Nikoonejad, Ali Shafizadeh Arjomandi, S. Dodangeh, A. Allami","doi":"10.52547/ajcm.28.1.13","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.13","url":null,"abstract":"Background and Objective: Coronavirus Disease 2019 (COVID-19) has caused the death of many people, mainly by causing respiratory failure. The method of quarantine for the control of this disease leads to deprivation of vitamin D3 production. In this regard, this study aimed to investigate the relationship between serum vitamin D3 level and risk of COVID-19. Materials and Methods: This case-control study was conducted in BouAli Sina Hospital in Qazvin, Iran in September 2020. The statistical population of the case group included patients with COVID-19 referred to this center, while the control group comprised non-COVID-19 patients who referred to the center. Vitamin D3 levels of the participants were assessed and the findings were recorded. The collected data were analyzed using statistical","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44176764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Tabasi, E. Mesdaghinia, Masoumeh Abedzadeh-kalahroudi, H. Akbari, Mahsa Bandagi-Motlagh
Background and Objective: Preeclampsia is one of the most critical complications of pregnancy observed in 2%-8% of all pregnancies. Severe preeclampsia has many maternal and neonatal complications that are more prevalent in early-onset preeclampsia. The present study aimed to determine the prevalence of maternal and neonatal outcomes of expectant management of severe preeclampsia before 34 weeks of gestation. Materials and Methods: In this retrospective descriptive study, the medical records of 55 mothers who had severe preeclampsia before 34 weeks of gestation and underwent expectant management and those of their neonates within 2014-2019 in Kashan, Iran, were reviewed. The information extracted from the medical records included maternal and neonatal demographic variables and outcomes. All data were analyzed in SPSS software (version 16) using descriptive and inferential statistics. The p-values of less than 0.05 were considered significant. Results: In this study, the rates of seizure, post-partum hemorrhage, intensive care unit admission, and platelet decline were 5.5%, 1.8%, 3.6%, and 7.3%, respectively. Moreover, 10.9% of mothers had renal failure, and therefore, elevated liver enzymes and hemolysis. Among the neonates, 44.7% and 12.7% of the cases had respiratory distress syndrome (RDS) and low Apgar scores, respectively. It was also revealed that 6.4% of the neonates had convulsions and pneumothorax (PTX), and neonatal mortality was observed in 6.4% of them. No significant relationship was observed between maternal outcomes and gestational age and between neonatal outcomes and the number of deliveries (P>0.05). However, renal failure outcomes had a significant relationship with the number of deliveries (P=0.023), meaning that all mothers with renal failure were nulliparous. It was found that gestational age had a significant relationship with the outcomes of neonatal death, low 5-minute Apgar score, low birth weight, RDS, and PTX (P<0.05); in other words, lower gestational age led to higher mentioned neonatal outcomes. Conclusion: Expectant management of early-onset preeclampsia was beneficial for neonates, and the implementation of regular and close monitoring in equipped centers would prevent the increase of maternal
{"title":"Maternal and Neonatal Outcomes in Expectant Management of Early-Onset Severe Preeclampsia","authors":"Z. Tabasi, E. Mesdaghinia, Masoumeh Abedzadeh-kalahroudi, H. Akbari, Mahsa Bandagi-Motlagh","doi":"10.52547/ajcm.28.1.28","DOIUrl":"https://doi.org/10.52547/ajcm.28.1.28","url":null,"abstract":"Background and Objective: Preeclampsia is one of the most critical complications of pregnancy observed in 2%-8% of all pregnancies. Severe preeclampsia has many maternal and neonatal complications that are more prevalent in early-onset preeclampsia. The present study aimed to determine the prevalence of maternal and neonatal outcomes of expectant management of severe preeclampsia before 34 weeks of gestation. Materials and Methods: In this retrospective descriptive study, the medical records of 55 mothers who had severe preeclampsia before 34 weeks of gestation and underwent expectant management and those of their neonates within 2014-2019 in Kashan, Iran, were reviewed. The information extracted from the medical records included maternal and neonatal demographic variables and outcomes. All data were analyzed in SPSS software (version 16) using descriptive and inferential statistics. The p-values of less than 0.05 were considered significant. Results: In this study, the rates of seizure, post-partum hemorrhage, intensive care unit admission, and platelet decline were 5.5%, 1.8%, 3.6%, and 7.3%, respectively. Moreover, 10.9% of mothers had renal failure, and therefore, elevated liver enzymes and hemolysis. Among the neonates, 44.7% and 12.7% of the cases had respiratory distress syndrome (RDS) and low Apgar scores, respectively. It was also revealed that 6.4% of the neonates had convulsions and pneumothorax (PTX), and neonatal mortality was observed in 6.4% of them. No significant relationship was observed between maternal outcomes and gestational age and between neonatal outcomes and the number of deliveries (P>0.05). However, renal failure outcomes had a significant relationship with the number of deliveries (P=0.023), meaning that all mothers with renal failure were nulliparous. It was found that gestational age had a significant relationship with the outcomes of neonatal death, low 5-minute Apgar score, low birth weight, RDS, and PTX (P<0.05); in other words, lower gestational age led to higher mentioned neonatal outcomes. Conclusion: Expectant management of early-onset preeclampsia was beneficial for neonates, and the implementation of regular and close monitoring in equipped centers would prevent the increase of maternal","PeriodicalId":52678,"journal":{"name":"pzshkhy blyny bn syn","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45661181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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