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Relationship between Serum Inhibin A and Pregnancy Outcomes 血清抑制素A与妊娠结局的关系
Q4 Medicine Pub Date : 2020-06-01 DOI: 10.21859/AJCM.27.1.30
S. Alimohammadi, Forogh Sehat, J. Porolajal, M. Faryadras
Background and Objective: Some studies have shown that abnormal levels of biomarkers may be associated with adverse pregnancy outcomes. This study aimed to investigate the association between serum levels of Inhibin A and the outcomes of pregnancy. Materials and Methods: This retrospective cohort study was conducted on the data obtained from the Inhibin A of 560 pregnant women at 15 to 20 weeks of gestation in Hamadan, Iran. The levels of Inhibin A less than 0.5 and higher than 2 mmol were considered below and high, respectively. The patients were assessed in terms of birth weight, gestational age, Apgar score, preeclampsia, intrauterine fetal death, and cesarean section. The receiver operating characteristic curve level was calculated to detect adverse pregnancy complications. The data were statistically analyzed in STATA software (version 14). Results: Out of the pregnant women eligible for the study, 33 (5.9%) cases were excluded due to incomplete medical record files and unavailability. Of the remaining 527 patients, 378 (71.7%), 26 (4.9%), and 123 (23.3%) ones had normal, low, had high Inhibin A levels, respectively. Patients with higher serum Inhibin A levels had a higher risk of preeclampsia, low birth weight, and prematurity, compared to those with normal or low levels (P˂0.05). Conclusion: Based on the findings of the present study, high levels of Inhibin A at 15 to 20 weeks of gestation can be associated with the risk of preeclampsia, low birth weight, and prematurity.
背景和目的:一些研究表明,生物标志物水平异常可能与不良妊娠结局有关。本研究旨在探讨血清抑制素A水平与妊娠结局之间的关系。材料和方法:这项回顾性队列研究是对伊朗哈马丹560名妊娠15至20周孕妇的抑制素A数据进行的。抑制素A水平低于0.5和高于2毫摩尔分别被认为低于和高于。根据出生体重、胎龄、Apgar评分、先兆子痫、宫内胎儿死亡和剖宫产对患者进行评估。计算受试者操作特征曲线水平,以检测不良妊娠并发症。数据在STATA软件(版本14)中进行统计分析。结果:在符合研究条件的孕妇中,33例(5.9%)病例因医疗记录文件不完整和不可用而被排除在外。在剩下的527名患者中,378名(71.7%)、26名(4.9%)和123名(23.3%)患者的抑制素A水平分别正常、低和高。与正常或低水平的患者相比,血清抑制素A水平较高的患者患先兆子痫、低出生体重和早产的风险更高(P 0.05)。
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引用次数: 0
Seroprevalence of Hydatidosis in Referrers to Laboratories of Khoda Afarin Health Center in East Azarbaijan, Iran, within 2018 to 2019 伊朗东阿塞拜疆Khoda Afarin卫生中心实验室2018 - 2019年包虫病血清阳性率分析
Q4 Medicine Pub Date : 2020-03-01 DOI: 10.21859/AJCM.26.4.234
M. Fallah, A. Azimi, S. Haghi, N. Sarafraz, M. Parsaei, Mahdiyeh Hassanzadeh, Saber Alizadeh, Ahad Shahnami, A. Nayebi
Background and Objective: Infection with hydatid cysts or hydatidosis, which is a zoonotic disease, is caused by the larval stage of Echinococcus granulosus in humans and animals. Hydatidosis infection is endemic in most parts of the country. In Khoda Afarin County in East Azarbaijan, Iran, as a center of animal husbandry, there is a possibility of high exposure to the Echinococcus granulosus egg. This study was carried out to determine the seroprevalence of hydatidosis in this county population. Materials and Methods: In this descriptive cross-sectional study, 295 blood samples were collected from the population of Khoda Afarin County in a test tube without anticoagulant within 2018 to 2019. The samples were evaluated using enzyme-linked immunosorbent assay to measure immunoglobulin G against Echinococcus granulosus. The demographic data of the participants were gathered by a questionnaire, and the results were analyzed using SPSS software (version 18). Results: Out of 295 samples, 12 (4.07%) people were positive. The highest percentage of seropositivity was reported in the age group of 30-39 years with 3 (3.53%) cases. The frequency rates of seropositivity in urban and rural subjects were 16.7% and 83.3%, respectively. Conclusion: The obtained results showed a significant prevalence of infection in the study population (similar to those reported in some other studies carried out in different parts of Iran). Therefore, it is essential to focus on the control and prevention of the disease as a priority disease in Khoda Afarin County among different occupations and age groups.
背景与目的:棘球蚴病是由细粒棘球蚴幼虫期在人和动物体内引起的一种人畜共患疾病。棘球蚴感染在该国大部分地区流行。在伊朗东阿扎拜詹的Khoda Afarin县,作为畜牧业中心,有可能大量接触细粒棘球蚴卵。本研究旨在确定该县人群中棘球蚴病的血清流行率。材料和方法:在这项描述性横断面研究中,在2018年至2019年期间,在不使用抗凝剂的试管中从科达阿法林县人群中采集了295份血液样本。使用酶联免疫吸附测定法对样品进行评估,以测量针对细粒棘球蚴的免疫球蛋白G。通过问卷调查收集参与者的人口统计数据,并使用SPSS软件(18版)对结果进行分析。结果:在295份样本中,12人(4.07%)呈阳性。血清阳性率最高的是30-39岁年龄组,有3例(3.53%)。城市和农村受试者的血清阳性率分别为16.7%和83.3%。结论:所获得的结果显示,研究人群中的感染率显著(与在伊朗不同地区进行的其他一些研究中报告的感染率相似)。因此,有必要将重点放在控制和预防该疾病上,将其作为霍达阿法林县不同职业和年龄组的优先疾病。
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引用次数: 0
Comparison of Ultrasound Findings of Carpal Tunnel Syndrome before and after Corticosteroid Injection 皮质类固醇注射前后腕管综合征的超声表现比较
Q4 Medicine Pub Date : 2020-03-01 DOI: 10.21859/AJCM.26.4.193
H. Golmohammadi, H. Saremi, A. Moradi, S. Pakmehr, Masoud Esnaashari
Background and Objective: Carpal Tunnel Syndrome is the most prevalent type of peripheral neuropathy due to neural entrapment. This syndrome is primarily diagnosed based on clinical symptoms, and it is subsequently confirmed by electro-diagnostic studies. Ultrasonography as a safe, available, and inexpensive method is also valuable in the follow-up of patients. This study aimed to evaluate the ultrasound findings before and after local corticosteroid injection. Materials and Methods: This interventional study was conducted on 45 patients referring to the orthopedic clinic of Besat Hospital, Hamadan, Iran, during 2017. The patients who were selected by convenient sampling method had the symptoms of carpal tunnel syndrome and were diagnosed positive based on electrodiagnostic studies indicating a moderate grade of the disease. Wrist ultrasound was performed before and after the injection of corticosteroid (two months later). Moreover, the ultrasound indices were compared before and after the injection. Data were analyzed in SPSS software (version 16). A p-value less than 0.05 was considered statistically significant. Results: According to the results, 80% of the patients were female. Moreover, the mean age of the patients was 47.9±11.6 years (age range: 2272 years). About 20% of the cases were left-handed. The right hand was mostly affected by carpal tunnel syndrome (70%). After injection, there were reductions in the median nerve thickness (P=0.95), retinaculum thickness (P=0.001), and nerve cross-sectional area (P=0.001). The Disabilities of the Arm, Shoulder, and Hand (DASH) scale showed that the clinical symptoms of the patients were significantly reduced at the end of the study (P=0.001). Conclusion: Corticosteroid injection in patients with moderate severity of carpal tunnel syndrome improved the clinical symptoms and caused reductions in median nerve thickness, cross-sectional area, and flexor retinaculum thickness.
背景与目的:腕管综合征是由神经卡压引起的最常见的周围神经病变类型。该综合征主要根据临床症状进行诊断,随后通过电诊断研究进行证实。超声检查作为一种安全、有效、廉价的方法,在患者的随访中也很有价值。本研究旨在评估局部皮质类固醇注射前后的超声检查结果。材料和方法:本介入研究于2017年在伊朗哈马丹贝萨特医院骨科诊所对45名患者进行。通过方便的抽样方法选择的患者有腕管综合征症状,并根据电诊断研究被诊断为阳性,表明该疾病为中度。在注射皮质类固醇前后(两个月后)进行腕关节超声检查。此外,还比较了注射前后的超声指标。数据采用SPSS软件(16版)进行分析。p值小于0.05被认为具有统计学意义。结果:根据结果,80%的患者为女性。此外,患者的平均年龄为47.9±11.6岁(年龄范围:2272岁)。大约20%的病例是左撇子。右手主要受到腕管综合征的影响(70%)。注射后,正中神经厚度(P=0.95)、支持带厚度(P=0.001)和神经横截面积(P=0.001,和手(DASH)量表显示,在研究结束时,患者的临床症状显著减轻(P=0.001)。结论:中等严重程度腕管综合征患者注射皮质类固醇改善了临床症状,并导致正中神经厚度、横截面积和屈肌支持带厚度减少。
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引用次数: 0
Serum Level of Helicobacter pylori Antibody in Stroke Patients 脑卒中患者血清幽门螺杆菌抗体水平测定
Q4 Medicine Pub Date : 2020-03-01 DOI: 10.21859/AJCM.26.4.206
Shahir Mazaheri, M. Khazaei, A. Moradi, R. Raei
Background and Objective: Stroke is the third most common cause of death in developed countries and the most common disabling neurological disease. There are several risk factors for stroke. Regarding this, the present study was conducted to investigate the effect of Helicobacter pylori antibody on the incidence of stroke. Materials and Methods: This case-control study was conducted on 50 patients (i.e., case group) with stroke admitted to Sina Teaching Hospital of Hamadan, Iran, using convenience sampling method. This group was compared with 50 healthy controls in terms of the serum level of Helicobacter pylori antibody. The data were analyzed using SPSS software (version 21) using proper statistical tests at 95% confidence interval. Results: The mean serum levels of Helicobacter pylori antibody in the case and control groups were 25.93±44.03 and 35.36±41.25 Uarb/ml, respectively (P=0.108). In addition, the serum levels of this antibody were obtained as 20.78 and 35.84 (P=0.055) in the females and 31.51 and 34.31 (P=0.501) in the males of the control and case groups, respectively. The Spearman correlation coefficient revealed a positive but insignificant relationship between age and serum antibody level of Helicobacter pylori in both groups (r=0.150; P=0.13). Conclusion: As the findings indicated, the stroke patients had a lower serum level of Helicobacter pylori antibody, compared to the healthy non-stroke patients; however, this difference was not statistically significant.
背景与目的:中风是发达国家第三大常见死因,也是最常见的致残神经系统疾病。中风有几个危险因素。为此,本研究旨在探讨幽门螺杆菌抗体对脑卒中发病率的影响。材料与方法:采用方便抽样方法,对伊朗哈马丹新浪教学医院收治的50例脑卒中患者(即病例组)进行病例对照研究。与50名健康对照组比较血清幽门螺杆菌抗体水平。使用SPSS软件(版本21)进行数据分析,并在95%置信区间内进行适当的统计检验。结果:病例组和对照组血清幽门螺杆菌抗体平均水平分别为25.93±44.03和35.36±41.25 Uarb/ml (P=0.108)。对照组和病例组女性血清中该抗体水平分别为20.78和35.84 (P=0.055),男性为31.51和34.31 (P=0.501)。Spearman相关系数显示两组患者年龄与血清幽门螺杆菌抗体水平呈正相关但不显著(r=0.150;P = 0.13)。结论:脑卒中患者血清幽门螺杆菌抗体水平较健康非脑卒中患者低;然而,这种差异在统计学上并不显著。
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引用次数: 0
Evaluation of the Factors Influencing Diabetic Control among Adolescents with Type 1 Diabetes 影响青少年1型糖尿病控制因素的评价
Q4 Medicine Pub Date : 2020-03-01 DOI: 10.29252/ajcm.26.4.227
A. Pirdehghan, Z. Razavi, R. Rajabi
Background and Objective: Type 1 diabetes is the most common metabolic and chronic disease in children and adolescents. This study aimed to evaluate the factors influencing diabetic control among adolescents with
背景与目的:1型糖尿病是儿童和青少年最常见的代谢性和慢性疾病。本研究旨在评估影响青少年糖尿病控制的因素
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引用次数: 0
Adjunctive Low-level Laser Therapy Using 980-nm Diode Laser after Impacted Mandibular Third Molar Surgery: A Randomized Clinical Trial 下颌阻生第三磨牙手术后使用980纳米二极管激光辅助低水平激光治疗:一项随机临床试验
Q4 Medicine Pub Date : 2020-03-01 DOI: 10.21859/AJCM.26.4.199
Sirus Risbaf-Fakoor, H. Hashemzehi, Hassanali Jahantigh, K. Arab, L. Gholami
Background and Objective: Extraction of impacted lower third molars is one of the most frequent surgeries of the oral cavity. This operation might be accompanied by inevitable complications, such as pain, swelling, and trismus after surgery. Therefore, the aim of this study was to evaluate the impact of low-intensity/power laser therapy on swelling and trismus after impacted mandibular third molar surgery. Materials and Methods: This randomized double-blind clinical trial was performed on 40 patients who required similar unilateral impacted third molars. These patients were randomly divided into two groups of 20, including the control group with no laser application and the test group receiving laser irradiation. In the intervention group, 1 cm of the tissue was irradiated immediately post-operation by 12 j/cm energy using a 980-nm laser setting with continuous wave mode at the output power of 200 MW for 60 s. Radiations were carried out at three regions, including two intraoral sites on the buccal and lingual sides of the operated area and an extraoral area on the joining point of the masseter muscle to the mandible. Inflammation and trismus were assessed by measuring the size of the face and maximum mouth opening on the second and seventh days after surgery. Results: Our findings demonstrated that in the laser group, on the second day post-operation the maximum mouth opening (trismus) was 28±6 and facial swelling was 217.8±12.8. The two groups were not significantly different on this day regarding the two evaluated variables (P>0.05). On the seventh day, trismus and facial swelling were reported as 39.85±6.97 and 209.2±13.45, respectively. Moreover, improvements were observed in the irradiated group at this time point. However, no statistically significant difference was found between the test and control group concerning these
背景与目的:阻生下第三磨牙拔除术是口腔最常见的手术之一。这种手术可能会伴随不可避免的并发症,如术后疼痛、肿胀和三体。因此,本研究的目的是评估低强度/功率激光治疗对下颌阻生第三磨牙手术后肿胀和牙痛的影响。材料和方法:这项随机双盲临床试验对40名需要类似单侧阻生第三磨牙的患者进行了研究。这些患者被随机分为两组,每组20人,包括不应用激光的对照组和接受激光照射的试验组。在干预组中,在手术后立即用12J/cm能量照射1cm的组织,使用980nm激光设置,输出功率为200MW,持续60s。在三个区域进行辐射,包括在手术区域的颊侧和舌侧上的两个口内部位和在咬肌与下颌骨的连接点上的一个口外区域。在手术后第二天和第七天,通过测量面部大小和最大口腔开口来评估炎症和牙痛。结果:我们的研究结果表明,激光组在术后第二天的最大口腔张开度(trismus)为28±6,面部肿胀为217.8±12.8。两组在这一天的两个评估变量没有显著差异(P>0.05)。第七天,三体和面部肿胀分别为39.85±6.97和209.2±13.45。此外,在这个时间点,在照射组中观察到了改善。然而,在这些方面,试验组和对照组之间没有发现统计学上的显著差异
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引用次数: 0
Investigation of the Antifungal Effect of Rosa Damascena Essential Oil and Mixed Mouthwash (Grape Vinegar and Rosa Damascena essential oil) Against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida glabrata 大马士革玫瑰精油和混合漱口液(葡萄醋和大马士革玫瑰精油)对白色念珠菌、杜氏念珠菌、拟平滑念珠菌和光滑念珠菌的抗菌作用研究
Q4 Medicine Pub Date : 2019-12-01 DOI: 10.21859/AJCM.26.3.151
Zahra Amiri Karladani, Seyed Shojaedin Shayegh, Seyed Mohammad Reza Hakimaneh, M. Naghizadeh, H. Shokri, A. Naeini
Background and Objective: Oral candidiasis is often caused by Candida albicans, followed by C. dubliniensis, C. parapsilosis, and C. glabrata. The present study aimed to investigate the antifungal effects of Rosa damascena (R. damascena) essential oil, mixed mouthwash of R. damascena essential oil and grape vinegar, as well as nystatin against various standard Candida
背景与目的:口腔念珠菌感染多由白色念珠菌引起,其次为杜氏念珠菌、副psilosis和光滑念珠菌。本研究旨在研究大马士革玫瑰精油、大马士革玫瑰精油和葡萄醋混合漱口水以及制霉菌素对各种标准念珠菌的抗真菌作用
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引用次数: 2
Refractive Error and Anterior Segment Parametric Changes in Patients with Posterior Capsular Opacification after Nd: YAG Laser Posterior Capsulotomy Nd: YAG激光后囊膜切开术后囊膜混浊患者的屈光不正和前段参数变化
Q4 Medicine Pub Date : 2019-12-01 DOI: 10.21859/AJCM.26.3.166
M. Alizadeh, N. Jiryaee, M. Molaei, F. Eslami
Background and Objective: Cataract is one of the most common causes of blindness in the world, and posterior capsular opacification (PCO) is the most common complication after cataract surgery. Nd: YAG laser posterior capsulotomy is a standard method for the treatment of PCO. The aim of this study was to investigate the effects of Yas laser capsulotomy on anterior segment parameters and lenticular astigmatism. Materials and Methods: In this randomized clinical trial study, a total of 37 eyes from 30 patients with posterior capsular opacity after uneventful phacoemulsification were enrolled and underwent Nd: YAG laser capsulotomy. Full ocular examination, including intraocular pressure and refractive errors, was performed on the samples. The AC depth, volume, and angle were measured by Pentacam before capsulotomy and 3 months
背景与目的:白内障是世界上最常见的致盲原因之一,后囊混浊是白内障手术后最常见的并发症。Nd:YAG激光后囊切开术是治疗多囊卵巢综合征的标准方法。本研究的目的是研究Yas激光晶状体囊切开术对眼前节参数和晶状体散光的影响。材料和方法:在这项随机临床试验研究中,共有37只眼来自30名在平静的超声乳化术后出现后囊混浊的患者,他们接受了Nd:YAG激光晶状体囊切开术。对样本进行了全面的眼部检查,包括眼压和屈光不正。在囊膜切开术前和3个月,用Pentacam测量AC深度、体积和角度
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引用次数: 0
Investiagtion of Mental Health of Females with HIV-Positive Husbands Referred to Counseling and Behavioral Centers in Hamadan, Iran during 2019 2019年伊朗哈马丹咨询和行为中心对艾滋病毒阳性丈夫的女性心理健康状况的调查
Q4 Medicine Pub Date : 2019-12-01 DOI: 10.21859/AJCM.26.3.181
A. Pirdehghan, V. Shakeri, S. H. Hashemi, Saman Torkashvand
Background and Objective: Human immunodeficiency virus (HIV) infection in males not only causes physical, psychological, economic, and social problems for this population, it may also affect the physical and mental health of their spouses. This study aimed to compare the wives of HIVpositive husbands with a control group regarding depression, anxiety, and
背景和目的:男性感染人类免疫缺陷病毒(HIV)不仅会给这一人群带来身体、心理、经济和社会问题,还可能影响其配偶的身心健康。本研究旨在比较HIV阳性丈夫的妻子与对照组在抑郁、焦虑和
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引用次数: 1
Investigation of the Relationship between Retinal Nerve Fiber Layer Thickness and Mild Cognitive Impairment 视网膜神经纤维层厚度与轻度认知障碍关系的研究
Q4 Medicine Pub Date : 2019-12-01 DOI: 10.21859/AJCM.26.3.158
S. Akbarzadeh, M. Mazdeh, Z. Cheraghi, Seyed Masoud Seyedan
Background and Objective: This study investigated the difference between patients with mild cognitive impairment and healthy controls using Optical Coherence Tomography (OCT) regarding Retinal Nerve Fiber Layer (RNFL) thickness. Materials and Methods: In total, 20 patients with mild cognitive impairment and 20 healthy controls were subjected to neurological examination in this case-control study. The examinations included Minimal Mental State Examination test, comprehensive examination of the eye, and OCT using SPECTRALIS. The data were analyzed to evaluate the thickness of RFNL through descriptive and analytical statistics. Both eyes were selected for analysis, and the patients with mild cognitive impairment were compared with the healthy controls regarding the RFNL thickness. Results: The mean age of the patients was 61.4±3.4 years (age range: 53-65 years), and the mean RNFL thickness in patients was 100±10.1 μm. Moreover, the mean values of RNFL thickness in the lower, upper, nasal, and temporal quadrants were 128±18.9, 119±12.2, 87±14.06, and 68±10.3 μm, respectively. There was no difference between females (99±13.2) and males (103±5.6) regarding the RNFL thickness. In addition, no significant difference was observed between the male and female age groups in terms of the RNFL thickness. Additionally, there was no significant difference between the patients (100±10.1) and control group (104±8.7) regarding the RNFL thickness. The chance of developing mild cognitive impairment is increased by 1.45 times with increasing age. It should be noted that this relationship was statistically significant (P<0.001). Conclusion: The results of this study indicate that patients with mild cognitive impairment had reduced RNFL thickness, compared to healthy controls. However, since this difference was not significant, it cannot be regarded as a proper approach for diagnosis and follow up of the patients.
背景和目的:本研究使用光学相干断层扫描(OCT)研究了轻度认知障碍患者和健康对照者在视网膜神经纤维层(RNFL)厚度方面的差异。材料和方法:本病例对照研究共对20名轻度认知障碍患者和20名健康对照者进行了神经系统检查。检查包括最低精神状态检查测试、眼睛综合检查和SPECTRAIS OCT。对数据进行分析,通过描述性和分析性统计来评估RFNL的厚度。选择两只眼睛进行分析,并将轻度认知障碍患者与健康对照组的RFNL厚度进行比较。结果:患者的平均年龄为61.4±3.4岁(年龄范围:53-65岁),患者的平均RNFL厚度为100±10.1μm。此外,下象限、上象限、鼻象限和颞象限的RNFL厚度平均值分别为128±18.9、119±12.2、87±14.06和68±10.3μm。在RNFL厚度方面,女性(99±13.2)和男性(103±5.6)之间没有差异。此外,在RNFL厚度方面,男性和女性年龄组之间没有观察到显著差异。此外,在RNFL厚度方面,患者(100±10.1)和对照组(104±8.7)之间没有显著差异。随着年龄的增长,患轻度认知障碍的几率增加了1.45倍。值得注意的是,这种关系具有统计学意义(P<0.001)。结论:本研究的结果表明,与健康对照组相比,轻度认知障碍患者的RNFL厚度减少。然而,由于这种差异并不显著,因此不能将其视为诊断和随访患者的正确方法。
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引用次数: 0
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pzshkhy blyny bn syn
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