Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.68-74
Setyo Teguh Waluyo, Ferry Armanza, Hariadi Yuseran, K. Halim
HIGHLIGHTS The characteristics of gynecology oncology services at Ulin Regional General Hospital before and after the COVID-19 pandemic were evaluated. There was a decrease of 19% in the number of visits by Gynecology Oncology Clinic patients at Ulin Regional General Hospital between the period of March 2019 - February 2020 and March 2020 - February 2021. ABSTRACT Objective: The aim of this study was to investigate the characteristics of the Gynecology Oncology Outpatient Clinic at Ulin Hospital Banjarmasin before and after the COVID-19 pandemic. Materials and Methods: This descriptive study utilized existing patient data from the Gynecology Oncology Outpatient Clinic at Ulin Hospital Banjarmasin covering the period from March 2019 to February 2021. The study received ethical approval from the Ulin General Hospital ethics committee with clearance number 10/I-Reg Research/RSUDU/23. The collected data was presented in a tabular format to compare the service characteristics before the pandemic (March 2019 - February 2020) and after the pandemic (March 2020 – February 2021). Results: During the periods of March 2019 – February 2020 and March 2020 – February 2021, there was a reduction of 19% in patient visits. The number of patients undergoing treatment also decreased, from 1081 patients (53.9%) in the period of March 2019 – February 2020 to 926 patients (46.1%) in the period of March 2020 – February 2021. Notably, there was a decrease in the number of patients undergoing surgical procedures, dropping from 76 patients (70.4%) in the period of March 2019 – February 2020 to 32 patients (29.6%) in the period of March 2020 – February 2021. A similar trend was seen in patients receiving chemotherapy, with the count decreasing from 1005 patients (52.9%) in the period of March 2019 – February 2020 to 894 patients (47.1%) in the period of March 2020 – February 2021. These changes were attributed to various hospital measures implemented to address the COVID-19 pandemic, including a reduction in outpatient clinic visits and the temporary suspension of surgical procedures from March 2020 to October 2020 to minimize potential exposure. Conclusion: The study highlights a noticeable decline in both the frequency of visits to the Gynecology Oncology Outpatient Clinic at Ulin Regional General Hospital Banjarmasin and the number of patients receiving treatment during the periods before and after the onset of the COVID-19 pandemic.
{"title":"Characteristics of outpatient gynecology oncology services before and after COVID-19 pandemic at Ulin Regional General Hospital, Banjarmasin, Indonesia","authors":"Setyo Teguh Waluyo, Ferry Armanza, Hariadi Yuseran, K. Halim","doi":"10.20473/mog.v31i22023.68-74","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.68-74","url":null,"abstract":"HIGHLIGHTS\u0000\u0000The characteristics of gynecology oncology services at Ulin Regional General Hospital before and after the COVID-19 pandemic were evaluated.\u0000There was a decrease of 19% in the number of visits by Gynecology Oncology Clinic patients at Ulin Regional General Hospital between the period of March 2019 - February 2020 and March 2020 - February 2021.\u0000\u0000 \u0000ABSTRACT\u0000Objective: The aim of this study was to investigate the characteristics of the Gynecology Oncology Outpatient Clinic at Ulin Hospital Banjarmasin before and after the COVID-19 pandemic.\u0000Materials and Methods: This descriptive study utilized existing patient data from the Gynecology Oncology Outpatient Clinic at Ulin Hospital Banjarmasin covering the period from March 2019 to February 2021. The study received ethical approval from the Ulin General Hospital ethics committee with clearance number 10/I-Reg Research/RSUDU/23. The collected data was presented in a tabular format to compare the service characteristics before the pandemic (March 2019 - February 2020) and after the pandemic (March 2020 – February 2021).\u0000Results: During the periods of March 2019 – February 2020 and March 2020 – February 2021, there was a reduction of 19% in patient visits. The number of patients undergoing treatment also decreased, from 1081 patients (53.9%) in the period of March 2019 – February 2020 to 926 patients (46.1%) in the period of March 2020 – February 2021. Notably, there was a decrease in the number of patients undergoing surgical procedures, dropping from 76 patients (70.4%) in the period of March 2019 – February 2020 to 32 patients (29.6%) in the period of March 2020 – February 2021. A similar trend was seen in patients receiving chemotherapy, with the count decreasing from 1005 patients (52.9%) in the period of March 2019 – February 2020 to 894 patients (47.1%) in the period of March 2020 – February 2021. These changes were attributed to various hospital measures implemented to address the COVID-19 pandemic, including a reduction in outpatient clinic visits and the temporary suspension of surgical procedures from March 2020 to October 2020 to minimize potential exposure.\u0000Conclusion: The study highlights a noticeable decline in both the frequency of visits to the Gynecology Oncology Outpatient Clinic at Ulin Regional General Hospital Banjarmasin and the number of patients receiving treatment during the periods before and after the onset of the COVID-19 pandemic.\u0000 ","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78901192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.80-85
Nofita Fachryandini, Taufiq Hidayat, E. Ernawati, M. A Rahman
HIGHLIGHTS The most common CHD was atrial septal defect for acyanotic CHD and Tetralogy of Fallot for cyanotic CHD. There was no association between maternal pre-pregnancy BMI and type of CHD in offspring. ABSTRACT Objectives: This study aimed to determine the association between maternal pre-pregnancy BMI and type of congenital heart disease (CHD) in offspring. Materials and Methods: This retrospective cross-sectional study involved all mothers of children with CHD who visited Pediatric Outpatient Unit at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2019. The maternal data were obtained from the KIA's (Maternal and Child Health) book or through anamnesis by telephone, while the offspring’s data were collected from medical records. The data were analyzed using the Chi-Square test. Significance was determined at a 5% level (p <0.05). Results: We studied 117 mothers of children with CHD. The most frequent maternal pre-pregnancy body mass index (BMI) was normal (BMI 17-23 kg/m2) accounting for 56.4% of the study population. The most common CHD was atrial septal defect (33.3%) among acyanotic patients and Tetralogy of Fallot (8.5%) among cyanotic patients. The Chi-Square test showed p=0.958 for the association between maternal pre-pregnancy BMI and type of CHD in offspring. Conclusion: There was no association between maternal pre-pregnancy BMI and type of CHD in offspring.
{"title":"Is maternal pre-pregnancy Body Mass Index associated with type of Congenital Heart Disease in offspring?","authors":"Nofita Fachryandini, Taufiq Hidayat, E. Ernawati, M. A Rahman","doi":"10.20473/mog.v31i22023.80-85","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.80-85","url":null,"abstract":"HIGHLIGHTS\u0000\u0000The most common CHD was atrial septal defect for acyanotic CHD and Tetralogy of Fallot for cyanotic CHD.\u0000There was no association between maternal pre-pregnancy BMI and type of CHD in offspring.\u0000\u0000 \u0000ABSTRACT\u0000Objectives: This study aimed to determine the association between maternal pre-pregnancy BMI and type of congenital heart disease (CHD) in offspring.\u0000Materials and Methods: This retrospective cross-sectional study involved all mothers of children with CHD who visited Pediatric Outpatient Unit at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2019. The maternal data were obtained from the KIA's (Maternal and Child Health) book or through anamnesis by telephone, while the offspring’s data were collected from medical records. The data were analyzed using the Chi-Square test. Significance was determined at a 5% level (p <0.05).\u0000Results: We studied 117 mothers of children with CHD. The most frequent maternal pre-pregnancy body mass index (BMI) was normal (BMI 17-23 kg/m2) accounting for 56.4% of the study population. The most common CHD was atrial septal defect (33.3%) among acyanotic patients and Tetralogy of Fallot (8.5%) among cyanotic patients. The Chi-Square test showed p=0.958 for the association between maternal pre-pregnancy BMI and type of CHD in offspring.\u0000Conclusion: There was no association between maternal pre-pregnancy BMI and type of CHD in offspring.\u0000 ","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77440308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.103-109
E. Ernawati, Jihan Qonitatillah, A. Sulistyono
HIGHLIGHTS Monochorionic monoamniotic (MCMA) twin pregnancy has a significant risk of perinatal morbidity and mortality, including intrauterine fetal death (IUFD). The risk of prematurity, the risk of death due to MCMA complications, the availability of the NICU, also high costs on preterm care were factors in deciding to terminate the pregnancy. The ideal time to deliver monochorionic twins in order to reduce the risks of cord entanglement, growth discrepancies, and intrauterine fetal death is still a point of controversy. Early diagnosis, intensive antenatal monitoring, patient and family decision would contribute to antenatal mortality reduction. ABSTRACT Objectives: To present the management of monochorionic monoamniotic (MCMA) twin pregnancy. Case Report: Advanced prenatal treatment has improved the prognosis for Monochorionic Monoamniotic (MCMA) pregnancies; however, there is still no agreement on how to handle MCMA twins. The authors report 2 cases of monoamniotic monochorionic twin pregnancies. In the first case, a 30-years-old primi pregnant woman detected MCMA at 14 weeks of gestation; no complications related to MCMA were found; she planned delivery at 32 weeks, but one of the babies died in the womb at 31/32 weeks pregnant, a live baby born by cesarean section. The second case was a 36-year-old pregnant woman, on her third pregnancy, diagnosed with MCMA after 12 weeks of pregnancy, no complications related to MCMA, the baby was born at 32 weeks pregnant, and both babies survived. The management was the same in both cases, but different outcomes were obtained; in case 1, the baby died allegedly due to cord entanglement, which could not be detected during pregnancy.
{"title":"The management of Monochorionic Monoamniotic (MCMA) twin pregnancy","authors":"E. Ernawati, Jihan Qonitatillah, A. Sulistyono","doi":"10.20473/mog.v31i22023.103-109","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.103-109","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Monochorionic monoamniotic (MCMA) twin pregnancy has a significant risk of perinatal morbidity and mortality, including intrauterine fetal death (IUFD).\u0000The risk of prematurity, the risk of death due to MCMA complications, the availability of the NICU, also high costs on preterm care were factors in deciding to terminate the pregnancy.\u0000The ideal time to deliver monochorionic twins in order to reduce the risks of cord entanglement, growth discrepancies, and intrauterine fetal death is still a point of controversy.\u0000Early diagnosis, intensive antenatal monitoring, patient and family decision would contribute to antenatal mortality reduction.\u0000\u0000 \u0000ABSTRACT\u0000Objectives: To present the management of monochorionic monoamniotic (MCMA) twin pregnancy.\u0000Case Report: Advanced prenatal treatment has improved the prognosis for Monochorionic Monoamniotic (MCMA) pregnancies; however, there is still no agreement on how to handle MCMA twins. The authors report 2 cases of monoamniotic monochorionic twin pregnancies. In the first case, a 30-years-old primi pregnant woman detected MCMA at 14 weeks of gestation; no complications related to MCMA were found; she planned delivery at 32 weeks, but one of the babies died in the womb at 31/32 weeks pregnant, a live baby born by cesarean section. The second case was a 36-year-old pregnant woman, on her third pregnancy, diagnosed with MCMA after 12 weeks of pregnancy, no complications related to MCMA, the baby was born at 32 weeks pregnant, and both babies survived. The management was the same in both cases, but different outcomes were obtained; in case 1, the baby died allegedly due to cord entanglement, which could not be detected during pregnancy.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76411060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.75-79
Annisa' Wigati Rozifa, Nova Elok Mardliyana, Irma Maya Puspita
HIGHLIGHTS Midwifery services are carried out by combining conventional and complementary midwifery services Types of complementary therapies applied by 52% of independent midwifery services in Surabaya consisted of aromatherapy, hypnotherapy, herbal medicine, baby massage and spa, maternity massage, oxytocin massage, and yoga. ABSTRACT Objectives: This study aimed to describe the implementation of complementary therapy among the independent midwifery practices in Surabaya, Indonesia. Materials and Methods: Employing a quantitative approach with a survey methodology, this study involved data collection through surveys administered to independent midwives practicing in Surabaya and midwives affiliated with independent midwifery practices. The questionnaires were containing the characteristics of the participants, the implementation of complementary therapies, and the complementary therapies integrated into the practice settings. Results: The findings revealed that 25 midwives (comprising 52%) provided complementary midwifery services, whereas 23 midwives (comprising 48%) abstained from incorporating complementary midwifery services into their independent midwifery practices. The types of complementary therapies implemented consisted of aromatherapy, hypnotherapy, herbal medicine, baby massage and spa, maternity massage, oxytocin massage, and yoga. Conclusion: This study concluded that 52% of independent midwives in Surabaya applied complementary therapy into their practices.
{"title":"Description of the implementation of complementary therapy in midwifery services in Surabaya, Indonesia","authors":"Annisa' Wigati Rozifa, Nova Elok Mardliyana, Irma Maya Puspita","doi":"10.20473/mog.v31i22023.75-79","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.75-79","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Midwifery services are carried out by combining conventional and complementary midwifery services\u0000Types of complementary therapies applied by 52% of independent midwifery services in Surabaya consisted of aromatherapy, hypnotherapy, herbal medicine, baby massage and spa, maternity massage, oxytocin massage, and yoga.\u0000\u0000 \u0000ABSTRACT\u0000Objectives: This study aimed to describe the implementation of complementary therapy among the independent midwifery practices in Surabaya, Indonesia.\u0000Materials and Methods: Employing a quantitative approach with a survey methodology, this study involved data collection through surveys administered to independent midwives practicing in Surabaya and midwives affiliated with independent midwifery practices. The questionnaires were containing the characteristics of the participants, the implementation of complementary therapies, and the complementary therapies integrated into the practice settings.\u0000Results: The findings revealed that 25 midwives (comprising 52%) provided complementary midwifery services, whereas 23 midwives (comprising 48%) abstained from incorporating complementary midwifery services into their independent midwifery practices. The types of complementary therapies implemented consisted of aromatherapy, hypnotherapy, herbal medicine, baby massage and spa, maternity massage, oxytocin massage, and yoga.\u0000Conclusion: This study concluded that 52% of independent midwives in Surabaya applied complementary therapy into their practices.\u0000 ","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79743946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.61-67
Maskasoni Maskasoni, J. Dewantiningrum
HIGHLIGHTS Oral misoprostol is more effective than vaginal misoprostol in cervical ripening as a part of induction of labor. Oral misoprostol is as safe as vaginal misoprostol. ABSTRACT Objective: To compare Bishop score changes and labor event between oral and vaginal misoprostol in pregnancy beyond 41 weeks. Materials and Methods: A total of 52 pregnant women with more than 41 weeks of gestation, had a Bishop score less than 5, and were undergoing induction labor were randomly divided into two groups: oral and vaginal misoprostol. In the oral misoprostol group, participants were given 25 mg of misoprostol in a solution with a concentration of 1 ug/ml every 2 hours. In the vaginal misoprostol group, a 25 mg misoprostol tablet was inserted into the posterior fornix every 6 hours. The two groups were compared in terms of Bishop score during the first 6 hours, changes in Bishop score, labor at term events, neonatal outcomes, complications, and side effects after the administration of misoprostol. Results: The oral group showed significantly higher changes in Bishop score compared to the vaginal group (5.5 vs 3.6; p=0.0001). The median interval times for induction of labor at term, induction at stage II, and induction at birth were found to be shorter in the oral misoprostol group compared to the vaginal group (7.3 hours vs 10.6 hours, 14.0 hours vs 16.8 hours, and 14.6 hours vs 17.6 hours; p=0.002, 0.003, 0.002). Labor at term occurred much more frequently in the oral group (53.8% vs 15.4%). Additionally, the oral misoprostol group had a 3.5 times higher likelihood of experiencing labor at term within the first 6 hours after the initial administration compared to the vaginal group (OR 3.5, 95% CI 1.33-9.23). Conclusion: Oral administration of misoprostol for cervical ripening has been demonstrated to be more effective than vaginal administration, greater bishop score changes while maintaining an equivalent level of safety.
作为引产的一部分,口服米索前列醇比阴道米索前列醇在宫颈成熟中更有效。口服米索前列醇和阴道使用米索前列醇一样安全。目的:比较妊娠41周以上口服和阴道米索前列醇的Bishop评分变化和产程事件。材料与方法:选取52例妊娠41周以上、Bishop评分小于5分的引产孕妇,随机分为口服和阴道米索前列醇两组。在口服米索前列醇组,每2小时给予25毫克米索前列醇溶液,浓度为1微克/毫升。阴道使用米索前列醇组,每6小时将米索前列醇片25 mg插入后穹窿。比较两组在使用米索前列醇后前6小时的Bishop评分、Bishop评分变化、足月分娩事件、新生儿结局、并发症和副作用。结果:口服组Bishop评分变化明显高于阴道组(5.5 vs 3.6;p = 0.0001)。与阴道组相比,口服米索前列醇组足月引产、II期引产和出生时引产的中位数间隔时间更短(7.3小时vs 10.6小时,14.0小时vs 16.8小时,14.6小时vs 17.6小时);P =0.002, 0.003, 0.002)。口腔组足月产程发生率更高(53.8% vs 15.4%)。此外,口服米索前列醇组在首次给药后6小时内发生足月分娩的可能性是阴道组的3.5倍(OR 3.5, 95% CI 1.33-9.23)。结论:口服米索前列醇用于宫颈成熟已被证明比阴道给药更有效,bishop评分变化更大,同时保持同等水平的安全性。
{"title":"The difference of Bishop score change and labor event between oral and vaginal misoprostol in pregnancy beyond 41 weeks","authors":"Maskasoni Maskasoni, J. Dewantiningrum","doi":"10.20473/mog.v31i22023.61-67","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.61-67","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Oral misoprostol is more effective than vaginal misoprostol in cervical ripening as a part of induction of labor.\u0000Oral misoprostol is as safe as vaginal misoprostol.\u0000\u0000 \u0000ABSTRACT\u0000Objective: To compare Bishop score changes and labor event between oral and vaginal misoprostol in pregnancy beyond 41 weeks.\u0000Materials and Methods: A total of 52 pregnant women with more than 41 weeks of gestation, had a Bishop score less than 5, and were undergoing induction labor were randomly divided into two groups: oral and vaginal misoprostol. In the oral misoprostol group, participants were given 25 mg of misoprostol in a solution with a concentration of 1 ug/ml every 2 hours. In the vaginal misoprostol group, a 25 mg misoprostol tablet was inserted into the posterior fornix every 6 hours. The two groups were compared in terms of Bishop score during the first 6 hours, changes in Bishop score, labor at term events, neonatal outcomes, complications, and side effects after the administration of misoprostol.\u0000Results: The oral group showed significantly higher changes in Bishop score compared to the vaginal group (5.5 vs 3.6; p=0.0001). The median interval times for induction of labor at term, induction at stage II, and induction at birth were found to be shorter in the oral misoprostol group compared to the vaginal group (7.3 hours vs 10.6 hours, 14.0 hours vs 16.8 hours, and 14.6 hours vs 17.6 hours; p=0.002, 0.003, 0.002). Labor at term occurred much more frequently in the oral group (53.8% vs 15.4%). Additionally, the oral misoprostol group had a 3.5 times higher likelihood of experiencing labor at term within the first 6 hours after the initial administration compared to the vaginal group (OR 3.5, 95% CI 1.33-9.23).\u0000Conclusion: Oral administration of misoprostol for cervical ripening has been demonstrated to be more effective than vaginal administration, greater bishop score changes while maintaining an equivalent level of safety.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84836756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.92-96
Rahajeng Mukhamad, Muhammad Nooryanto, Dzikrifishofa, Article Info
HIGHLIGHTS Serum vitamin D levels were significantly different between POP and in healthy women. Micronutrient MMP-1 expression is increased in POP patients. ABSTRACT Objective: Pelvic Organ Prolapse (POP) is when pelvic tissues sink into the vagina due to weakened ligaments or muscles. POP is common globally. Adequate nutrition, including Vitamin D, is vital for prevention. Vitamin D maintains bone and muscle health, regulates MMP-9 to control collagen, essential for pelvic support. Increased MMPs lead to collagen breakdown and POP. Recognizing vitamin D's role in collagen and POP is crucial for prevention. This study aimed to determine definitive association between vitamin D, collagen type I and MMP-1 in POP patients. Materials and Methods: Our search yielded 1375 studies, of which 7 were included in the present investigation. Two studies addressed the micronutrient status of vitamin D, four investigated the micronutrient status of type 1 collagen, and two studied the micronutrient status of MMP-1 in postpartum POP patients. Results: The results showed that the mean of vitamin D levels from POP group was substantially decreased compared to a those of healthy women in the control group (95% confidence interval (CI), -3.64; -3.44 and p <0.05). There was a decrease of collagen I protein in POP (95% CI, -3.26; -2.45. p <0.05). Additionally, MMP-1 expression increased in POP patient (95% CI. 1.48-2.23, p <0.05) Conclusion: Micronutrient status was severely compromised in POP group compared to control subjects.
血清维生素D水平在POP和健康女性之间有显著差异。微量营养素MMP-1表达在POP患者中升高。摘要:目的:盆腔器官脱垂(POP)是指由于韧带或肌肉减弱导致盆腔组织下沉到阴道内。POP在全球都很普遍。充足的营养,包括维生素D,对预防至关重要。维生素D维持骨骼和肌肉健康,调节MMP-9以控制胶原蛋白,对骨盆支持至关重要。增高的MMPs会导致胶原蛋白分解和POP。认识到维生素D在胶原蛋白和POP中的作用对预防至关重要。本研究旨在确定POP患者维生素D、I型胶原蛋白和MMP-1之间的确切关系。材料和方法:我们检索了1375项研究,其中7项纳入了本研究。两项研究研究了维生素D的微量营养素状况,四项研究了1型胶原蛋白的微量营养素状况,两项研究了产后POP患者MMP-1的微量营养素状况。结果:结果显示,与对照组健康女性相比,POP组维生素D水平的平均值显著降低(95%置信区间(CI), -3.64;-3.44, p <0.05)。POP中I型胶原蛋白减少(95% CI, -3.26;-2.45。p < 0.05)。此外,MMP-1表达在POP患者中升高(95% CI)。(1.48-2.23, p <0.05)结论:与对照组相比,POP组微量营养素状况严重受损。
{"title":"The effect of micronutrients on postpartum pelvic organ prolapse patients","authors":"Rahajeng Mukhamad, Muhammad Nooryanto, Dzikrifishofa, Article Info","doi":"10.20473/mog.v31i22023.92-96","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.92-96","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Serum vitamin D levels were significantly different between POP and in healthy women.\u0000Micronutrient MMP-1 expression is increased in POP patients.\u0000\u0000 \u0000ABSTRACT\u0000Objective: Pelvic Organ Prolapse (POP) is when pelvic tissues sink into the vagina due to weakened ligaments or muscles. POP is common globally. Adequate nutrition, including Vitamin D, is vital for prevention. Vitamin D maintains bone and muscle health, regulates MMP-9 to control collagen, essential for pelvic support. Increased MMPs lead to collagen breakdown and POP. Recognizing vitamin D's role in collagen and POP is crucial for prevention. This study aimed to determine definitive association between vitamin D, collagen type I and MMP-1 in POP patients.\u0000Materials and Methods: Our search yielded 1375 studies, of which 7 were included in the present investigation. Two studies addressed the micronutrient status of vitamin D, four investigated the micronutrient status of type 1 collagen, and two studied the micronutrient status of MMP-1 in postpartum POP patients.\u0000Results: The results showed that the mean of vitamin D levels from POP group was substantially decreased compared to a those of healthy women in the control group (95% confidence interval (CI), -3.64; -3.44 and p <0.05). There was a decrease of collagen I protein in POP (95% CI, -3.26; -2.45. p <0.05). Additionally, MMP-1 expression increased in POP patient (95% CI. 1.48-2.23, p <0.05)\u0000Conclusion: Micronutrient status was severely compromised in POP group compared to control subjects.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84064222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.86-91
Muhammad Agung Khoiri, M. F. G. Siregar, S. Lumbanraja, I. H. Effendi, Yudha Sudewo, E. Ardiansyah, P. Eyanoer
HIGHLIGHTS Testosterone level correlates with FSFI score, showing that sexual function correlates with hormonal physiology. FSFI is a valid and useful tool in measuring sexual function. ABSTRACT Objective: This research aimed to analyze the correlation between testosterone levels and sexual function in postmenopausal women. Materials and Methods: This research was a descriptive observational study with a case series approach conducted at Aras Kabu Health Center Outpatient Polyclinic from May to August 2022. The normality test was carried out using the Shapiro-Wilk test. If the data were not normally distributed, data would be analyzed using the Spearman correlation test. If the data were normally distributed, the data analysis would use the Pearson correlation test. Results: There was a significant relationship between Female Sexual Function Index (FSFI) score with testosterone levels and duration of menopause with p<0.05. The degree of correlation found was 0.619 between testosterone levels and FSFI scores, indicating a moderate and significant positive correlation. A correlation degree of 0.482 was found between FSFI and length of menopause which indicated a significant moderate positive correlation, while the degree of correlation between testosterone levels and length of menopause was found to be 0.711, showing a strong and significant positive correlation. Conclusion: There is a significant relationship between FSFI scores with testosterone levels and duration of menopause as well. There was also a significant relationship between testosterone levels and the duration of menopause.
{"title":"Testosterone and sexual function in menopausal women based on the Female Sexual Function Index (FSFI) score","authors":"Muhammad Agung Khoiri, M. F. G. Siregar, S. Lumbanraja, I. H. Effendi, Yudha Sudewo, E. Ardiansyah, P. Eyanoer","doi":"10.20473/mog.v31i22023.86-91","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.86-91","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Testosterone level correlates with FSFI score, showing that sexual function correlates with hormonal physiology.\u0000FSFI is a valid and useful tool in measuring sexual function.\u0000\u0000 \u0000ABSTRACT\u0000Objective: This research aimed to analyze the correlation between testosterone levels and sexual function in postmenopausal women.\u0000Materials and Methods: This research was a descriptive observational study with a case series approach conducted at Aras Kabu Health Center Outpatient Polyclinic from May to August 2022. The normality test was carried out using the Shapiro-Wilk test. If the data were not normally distributed, data would be analyzed using the Spearman correlation test. If the data were normally distributed, the data analysis would use the Pearson correlation test.\u0000Results: There was a significant relationship between Female Sexual Function Index (FSFI) score with testosterone levels and duration of menopause with p<0.05. The degree of correlation found was 0.619 between testosterone levels and FSFI scores, indicating a moderate and significant positive correlation. A correlation degree of 0.482 was found between FSFI and length of menopause which indicated a significant moderate positive correlation, while the degree of correlation between testosterone levels and length of menopause was found to be 0.711, showing a strong and significant positive correlation.\u0000Conclusion: There is a significant relationship between FSFI scores with testosterone levels and duration of menopause as well. There was also a significant relationship between testosterone levels and the duration of menopause.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74447533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.20473/mog.v31i22023.97-102
Anak Agung Ngurah, Jaya Kusuma, Article Info
The coronavirus disease 2019 (COVID-19) is still classified as a world pandemic. This disease can affect numerous systems of the human body. Pregnant women are classified as a vulnerable group since COVID-19 can cause high morbidity and mortality. Angiotensin-converting enzyme-2 (ACE-2) acts as a COVID-19 receptor, and this receptor is also present in the placenta. The placenta plays a significant part in the fetus, especially protecting it from harmful conditions. Since only a few studies are available, COVID-19’s influence on the placenta in pregnancy needs to be discussed further. The SARS-CoV-2-infected pregnant woman’s placenta showed histopathological alterations. Viral particles were detected on syncytiotrophoblast and chorionic villi vascular endothelial cells. Some studies show inflammatory conditions are not prominent in SARS-CoV-2 positive infection. This, perhaps due to the placenta’s immunological reaction, plays a significant role. The SARS-CoV-2 disorder tends to cause abnormalities within the placental tissue. Fetal vascular malperfusion (FVM) and maternal vascular malperfusion (MVM) are the most frequent findings from the studies included.
{"title":"Impact of COVID-19 on the histopathological aspect of the placenta during pregnancy","authors":"Anak Agung Ngurah, Jaya Kusuma, Article Info","doi":"10.20473/mog.v31i22023.97-102","DOIUrl":"https://doi.org/10.20473/mog.v31i22023.97-102","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) is still classified as a world pandemic. This disease can affect numerous systems of the human body. Pregnant women are classified as a vulnerable group since COVID-19 can cause high morbidity and mortality. Angiotensin-converting enzyme-2 (ACE-2) acts as a COVID-19 receptor, and this receptor is also present in the placenta. The placenta plays a significant part in the fetus, especially protecting it from harmful conditions. Since only a few studies are available, COVID-19’s influence on the placenta in pregnancy needs to be discussed further. The SARS-CoV-2-infected pregnant woman’s placenta showed histopathological alterations. Viral particles were detected on syncytiotrophoblast and chorionic villi vascular endothelial cells. Some studies show inflammatory conditions are not prominent in SARS-CoV-2 positive infection. This, perhaps due to the placenta’s immunological reaction, plays a significant role. The SARS-CoV-2 disorder tends to cause abnormalities within the placental tissue. Fetal vascular malperfusion (FVM) and maternal vascular malperfusion (MVM) are the most frequent findings from the studies included.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74059840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-27DOI: 10.20473/mog.v31i12023.30-35
Putri Ardina Sari Nainggolan, M. Rusda, Dwi Faradina, A. D. Lubis
HIGHLIGHTS Leiomyoma is still the most common case in women aged 41–50 years. Women who have an obese BMI are the main risk factor for abnormal uterine bleeding, so it is urged for women to maintain an ideal weight because it can be bad for health. ABSTRACT Objective: This study identified the incidence of Abnormal Uterine Bleeding (AUB) at Haji Adam Malik General Hospital, Medan, Indonesia, in 2020-2021. Materials and Methods: This was a descriptive study with a cross-sectional design. Sampling was taken using total sampling and using retrospective data in the form of medical records with a diagnosis of AUB at Haji Adam Malik General Hospital Medan in 2020–2021. Results: There were 197 cases of AUB, with the highest distribution in the age group of 41–50 years with 84 people (42.6%). The most cases of AUB with an obese BMI were 91 people (46.2%), married status as many as 176 people (89.3%), had the last education level of senior high school as many as 99 people (50.3%), 144 people (73.1%) got their first menstruation when they were >12 years old, 80 people (40.6%) had multiparity, 90 people (45.7%) received medical therapy. Based on the PALM-COEIN classification, the most AUB cases were AUB-L with 99 people (50.3%). Based on the classification of AUB-L locations, most locations were submucosa with 38.6%. Conclusion: AUB-L cases were still the most common cases at Haji Adam Malik General Hospital, Medan, Indonesia, in 2020–2021.
重点:平滑肌瘤仍然是41-50岁女性最常见的病例。体重指数过高的女性是子宫异常出血的主要危险因素,因此女性应保持理想体重,因为这可能对健康有害。摘要:目的:了解2020-2021年印尼棉兰Haji Adam Malik总医院异常子宫出血(AUB)的发生率。材料和方法:这是一项横断面设计的描述性研究。2020-2021年在棉兰哈吉亚当马利克综合医院,采用总抽样和以诊断为AUB的病历形式的回顾性数据进行抽样。结果:AUB 197例,以41 ~ 50岁年龄段分布最多,84例(42.6%)。体重指数为肥胖的AUB患者最多91人(46.2%),已婚176人(89.3%),最低学历为高中99人(50.3%),>12岁第一次月经144人(73.1%),多胎80人(40.6%),接受药物治疗90人(45.7%)。根据PALM-COEIN分类,AUB病例以AUB- l型最多,99例(50.3%)。根据AUB-L的位置分类,以粘膜下层居多,占38.6%。结论:2020-2021年,印尼棉兰Haji Adam Malik总医院的AUB-L病例仍是最常见的病例。
{"title":"Abnormal Uterine Bleeding (AUB) at Haji Adam Malik General Hospital, Medan, North Sumatera, Indonesia","authors":"Putri Ardina Sari Nainggolan, M. Rusda, Dwi Faradina, A. D. Lubis","doi":"10.20473/mog.v31i12023.30-35","DOIUrl":"https://doi.org/10.20473/mog.v31i12023.30-35","url":null,"abstract":"HIGHLIGHTS\u0000\u0000Leiomyoma is still the most common case in women aged 41–50 years.\u0000Women who have an obese BMI are the main risk factor for abnormal uterine bleeding, so it is urged for women to maintain an ideal weight because it can be bad for health.\u0000\u0000 \u0000ABSTRACT\u0000Objective: This study identified the incidence of Abnormal Uterine Bleeding (AUB) at Haji Adam Malik General Hospital, Medan, Indonesia, in 2020-2021.\u0000Materials and Methods: This was a descriptive study with a cross-sectional design. Sampling was taken using total sampling and using retrospective data in the form of medical records with a diagnosis of AUB at Haji Adam Malik General Hospital Medan in 2020–2021.\u0000Results: There were 197 cases of AUB, with the highest distribution in the age group of 41–50 years with 84 people (42.6%). The most cases of AUB with an obese BMI were 91 people (46.2%), married status as many as 176 people (89.3%), had the last education level of senior high school as many as 99 people (50.3%), 144 people (73.1%) got their first menstruation when they were >12 years old, 80 people (40.6%) had multiparity, 90 people (45.7%) received medical therapy. Based on the PALM-COEIN classification, the most AUB cases were AUB-L with 99 people (50.3%). Based on the classification of AUB-L locations, most locations were submucosa with 38.6%.\u0000Conclusion: AUB-L cases were still the most common cases at Haji Adam Malik General Hospital, Medan, Indonesia, in 2020–2021.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84330714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIGHLIGHTS There were no significant differences in TMSC, sperm motility, sperm morphology, and DFI in sperm preparation using the swim-up method at 27°C and 37°C. However, this study provided an overview of the average improvement of DFI at 27°C compared to 37°C. There was no significant difference in the pregnancy rate of IUI in sperm preparation using the swim-up method at 27°C and 37°C. ABSTRACT Objective: This study aimed to determine the effect of temperature during sperm preparation on total sperm motile count (TMSC), sperm motility, sperm morphology, DNA fragmentation index (DFI), and pregnancy rate. Materials and Methods: A quasi-experimental laboratory study with pre- and post-test control group was conducted at Sekar Fertility Clinic, Dr. Moewardi General Hospital, Surakarta, Indonesia. A total of 20 sperm samples from infertile patients were prepared using the swim-up method at 27°C (group 1) and 37°C (group 2). TMSC, motility, morphology, and DFI examinations were performed. In addition, IUI was performed to confirm pregnancy rate. Sperm DNA fragmentation was determined using Sperm Chromatin Dispersion/SpermFunc DNAf test. Sperm DNA fragmentation was characterized by a halo <30% of the volume of the sperm head. Results: Group 1 had mean TMSC of 13.77 ± 9.30, while group 2 had 14.82 ± 8.82; p=0.218. Group 1 had a motility value 82.25+12.77 and group 2 had 82.55 ± 11.69; p=0.968. The morphological value for group 1 was 11.25 ± 5.15 and group 2 was 11.6 ± 5.34; p=0.626. The mean DFI for group 1 was 17.79 ± 10.88 and group 2 was 18.18 ± 12.95; p=0.765. Pregnancy rate in group 1 was 10% and group 2 was 20%; p=1.000. Conclusion: There were no significant differences in TMSC, sperm motility, sperm morphology, DFI, and pregnancy rate in sperm preparation using the swim-up method at 27°C and 37°C.
{"title":"The success rate of intrauterine insemination in sperm preparation swim-up method at room temperature compared to the incubator temperature","authors":"Eriana Melinawati, Uki Retno Budihastuti, M. Pangestu, Teguh Prakosa, Affi Angelia Ratnasari, A. Laqif, Darto, Cahyono Hadi, Lunardhi Susanto, Metanolia Sukmawati, Rakano Kautsar Dwiyana, Alfi Marita Tristiarti, Abida Zuhra Jatiningtyas","doi":"10.20473/mog.v31i12023.11-16","DOIUrl":"https://doi.org/10.20473/mog.v31i12023.11-16","url":null,"abstract":"HIGHLIGHTS\u0000\u0000There were no significant differences in TMSC, sperm motility, sperm morphology, and DFI in sperm preparation using the swim-up method at 27°C and 37°C. However, this study provided an overview of the average improvement of DFI at 27°C compared to 37°C.\u0000There was no significant difference in the pregnancy rate of IUI in sperm preparation using the swim-up method at 27°C and 37°C.\u0000\u0000 \u0000ABSTRACT\u0000Objective: This study aimed to determine the effect of temperature during sperm preparation on total sperm motile count (TMSC), sperm motility, sperm morphology, DNA fragmentation index (DFI), and pregnancy rate.\u0000Materials and Methods: A quasi-experimental laboratory study with pre- and post-test control group was conducted at Sekar Fertility Clinic, Dr. Moewardi General Hospital, Surakarta, Indonesia. A total of 20 sperm samples from infertile patients were prepared using the swim-up method at 27°C (group 1) and 37°C (group 2). TMSC, motility, morphology, and DFI examinations were performed. In addition, IUI was performed to confirm pregnancy rate. Sperm DNA fragmentation was determined using Sperm Chromatin Dispersion/SpermFunc DNAf test. Sperm DNA fragmentation was characterized by a halo <30% of the volume of the sperm head.\u0000Results: Group 1 had mean TMSC of 13.77 ± 9.30, while group 2 had 14.82 ± 8.82; p=0.218. Group 1 had a motility value 82.25+12.77 and group 2 had 82.55 ± 11.69; p=0.968. The morphological value for group 1 was 11.25 ± 5.15 and group 2 was 11.6 ± 5.34; p=0.626. The mean DFI for group 1 was 17.79 ± 10.88 and group 2 was 18.18 ± 12.95; p=0.765. Pregnancy rate in group 1 was 10% and group 2 was 20%; p=1.000.\u0000Conclusion: There were no significant differences in TMSC, sperm motility, sperm morphology, DFI, and pregnancy rate in sperm preparation using the swim-up method at 27°C and 37°C.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90756629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}