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Problem diagnostic of Krukenberg tumor Krukenberg肿瘤的诊断问题
Pub Date : 2019-05-23 DOI: 10.20473/MOG.V1I12019.34-39
Reza Wangsanagara, Pungky Mulawardhana, Vicky Sumarki, A. S. Rahaju, Tri Wulanhandarini
Objectives: to report the case of Krukenberg tumor in 57 years old woman, with complaints of abdominal enlargement since the last 10 months.Case Report: a 57 years old woman, multipara, post menopause, came to our hospital with complaints of enlarging abdomen. Abdominal physical examination showed enlarging abdomen, hard palpable mass, measured 17 cm in diameter, and limited mobility. Abdominal CT result showed solid mass of the right adnexal, expanding to upper right abdomen, omental cake, ascites, and left pleural effusion, right lobe hepatic cyst and multiple bilateral renal cysts. Patient was diagnosed as solid ovarian tumor, suspicious of malignancy. Colonoscopy revealed hemorrhoid interna. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was done. Histopathologic findings showed malignant ovarian tumor, signet ring cell carcinoma of the cervics, endometrium, myometrium, nodule in gastrocolica ligament, and prevesica urinaria nodule. IHC examination of the ovarian tumor showed possible source was of colorectal, supporting the diagnosis of Krukenberg tumor with CK20 (+) and CK7 (-)Conclusion: Krukenburg tumor is a rare ovarian malignancy. Clinical symptoms usually consist of abdominal distension, pain caused by large ovarian mass. Diagnosis of Krukenburg tumor is confirmed by characteristic histologic findings of malignant signet ring cells with cellular stroma. Management for ovarian tumor is surgery removal, with very poor prognosis.
目的:报告57岁女性Krukenberg肿瘤病例,自10个月以来主诉腹部增大。病例报告:一名57岁女性,多产妇,绝经后,以腹部增大为主诉来我院就诊。腹部体格检查:腹部肿大,可触及硬肿块,直径17cm,活动受限。腹部CT示右附件实性肿块,扩张至右上腹部,大网膜饼,腹水,左胸膜积液,右肺叶肝囊肿,双侧多发肾囊肿。诊断为卵巢实性肿瘤,怀疑恶性。结肠镜检查显示内痔。行全腹子宫切除术并双侧输卵管卵巢切除术。组织病理表现为卵巢恶性肿瘤、宫颈印戒细胞癌、子宫内膜、子宫肌层、胃结肠韧带结节及尿道前缩结节。卵巢免疫组化检查显示肿瘤可能来源于结直肠,结合CK20(+)和CK7(-),支持Krukenburg肿瘤的诊断。结论:Krukenburg肿瘤是一种罕见的卵巢恶性肿瘤。临床症状通常为腹胀、卵巢大肿块引起的疼痛。Krukenburg肿瘤的诊断是由恶性印戒细胞与细胞间质的特征性组织学表现所证实。卵巢肿瘤的治疗是手术切除,预后很差。
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引用次数: 0
Passive smoker during pregnancy is a risk factor of low birth weight 怀孕期间被动吸烟是低出生体重的危险因素
Pub Date : 2019-05-23 DOI: 10.20473/MOG.V1I12019.12-16
Kanda Izzatul Aini Ardelia, Gatut Hardianto, Djohar Nuswantoro
Objectives: to analyze the relationship between passive smoker of pregnant women with low birth weight (LBW).Materials and Methods: This study is an observational analytic research with case control design, which is LBW as case group and normal birth weight as control group. The location is in Wonokusumo Health Centre, Surabaya, period January 2016 – December 2017. Study sample was 68, consisting of 34 cases and 34 controls. The dependent variable is LBW, while the inde-pendent variable is passive smoking of pregnant women. Sample was excluded multiple births and congenital defects. To determine a significant level, the data collected will be tested with the statistical test Chi-square at significance level ?=0.05.Results: The results showed that a majority (61.5%) of passive smoker of pregnant women are cases. After Chi-square test obtained by value p=0.027 (p?0,05) and OR analysis obtained by 3.04 (CI 95% 1.117 – 8.274), which means there is a relationship between passive smoker of pregnant women with LBW.Conclusion: Passive smoker of pregnant women is relationship with decreased birth weight.
目的:分析低出生体重孕妇被动吸烟的关系。材料与方法:本研究以低出生体重为病例组,正常出生体重为对照组,采用病例对照设计进行观察性分析研究。该地点位于泗水的Wonokusumo健康中心,时间为2016年1月至2017年12月。研究样本为68例,包括34例病例和34例对照组。因变量是LBW,而独立变量是孕妇的被动吸烟。样本排除了多胞胎和先天性缺陷。为了确定显著性水平,将使用显著性水平的统计检验卡方对收集的数据进行检验=结果:孕妇被动吸烟者以例居多(61.5%)。经卡方检验,p=0.027(p?0.05),OR分析,3.04(CI 95%1.117–8.274),表明孕妇被动吸烟与LBW之间存在关系。
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引用次数: 7
Characteristics of Peripartum Cardiomyopathy (PPCM) pregnancy and preeclampsia in Dr Soetomo Hospital, Surabaya, Indonesia, 2014-2016 2014-2016年印度尼西亚泗水Soetomo医生医院围产期心肌病(PPCM)妊娠和先兆子痫的特征
Pub Date : 2019-05-23 DOI: 10.20473/MOG.V1I12019.40-44
Dibya Arfianda, B. Wicaksono, K. E. Gumilar, A. Andrianto
Objectives: to present data on the characteristics of pregnancy with PPCM and PE. Management of patients with PPCM is almost the same as for patients with acute or chronic heart failure, which uses drug therapy. PPCM and preeclampsia (PE) are two related diseases, although not directly. Both have similar pathophysiological mechanisms.Case Report: We present 25 pregnancy cases with PPCM at Dr. Soetomo Hospital within 3 years. Data were collected from January 2014 to December 2016, consisting of 5 PPCM cases and the other 20 cases were PPCM with PE cases.Conclusion: Pregnancy with PPCM-PE has higher morbidity than PPCM only. The diagnosis of PPCM should be established immediately if heart failure symptoms are found in the third trimester and the patient has risk factors, such as age >30 years, multigravida, obesity, and multiple pregnancy.
目的:介绍PPCM和PE合并妊娠的特点。PPCM患者的治疗方法与急性或慢性心力衰竭患者几乎相同,均采用药物治疗。PPCM和先兆子痫(PE)是两种相关疾病,尽管没有直接关系。两者具有相似的病理生理机制。病例报告:我们报告了3年内在Dr. Soetomo医院发生的25例PPCM妊娠病例。资料收集时间为2014年1月至2016年12月,其中PPCM 5例,PPCM合并PE 20例。结论:妊娠合并PPCM- pe的发病率高于单纯PPCM。如果在妊娠晚期发现心衰症状,且患者有危险因素,如年龄0 ~ 30岁、多胎、肥胖、多胎妊娠,应立即确定PPCM的诊断。
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引用次数: 2
Default sequence of Mozart’s compositions during pregnancy gave higher dendritic density in the cerebrum and cerebellum of Rattus norvegicus offsprings compared with reversed sequence and control 莫扎特作品在怀孕期间的默认序列与反向序列和对照相比,褐家鼠后代大脑和小脑中的树突密度更高
Pub Date : 2019-05-23 DOI: 10.20473/MOG.V1I12019.5-11
Harry Panjaitan, H. T. Joewono, W. Widjiati
Objectives: This study aim to determine sequence of Mozart songs in the analyzing differences in dendritic density of cerebellum and cerebellum of new born Rattus novergicusMaterials and Methods: Experimental study randomized post test only control group design using Rattus norvegicus. Animal subjects were divided into three groups which were control group, and the treatment group that were given exposure to default sequence and reversed sequence of Mozart's music from gestation day 10. We used a comparison test in the analysis expression of BDNF.Results: In the cerebrum there was a significant difference in the Mozart group in reverse rather than with Mozart standard sequence and in standard Mozart group with no exposure group, with p=0.003 and p=0.000. In the cerebellum there was a significant difference in the group in reverse rather than with standard Mozart and in the standard Mozart group with the control group, with p=0.000 and p=0.000. However, there was no significant difference between control group and Mozart group upside down in cerebrum and cerebellum with p=0.109 and p=0.077Conclusion: The density of dendrites in the cerebrum and cerebellum of Rattus norvegicus newborn exposed to Mozart's music during pregnancy with standard Mozart sequence was higher than that in those receiving reverse order and without exposure. There were no significant differences between the density of the cerebrum and cerebellum dendrites between groups exposed to reversed sequence of Mozart composition and those without exposure.
目的:本研究旨在确定莫扎特歌曲的顺序,以分析新生新生褐家鼠小脑和小脑树突密度的差异。材料和方法:实验研究采用褐家鼠随机试验后对照组设计。动物受试者被分为三组,即对照组和治疗组,从妊娠第10天开始接触莫扎特音乐的默认序列和反向序列。结果:在大脑中,与莫扎特标准序列相反的莫扎特组与无暴露组相比,有显著差异,p=0.003和p=0.000。在小脑中,与标准莫扎特组相反,标准莫扎特组与对照组有显著差异,p=0.000和p=0.000。但对照组和倒置莫扎特组的大脑和小脑无显著差异,p分别为0.109和0.077。暴露于莫扎特倒序乐曲组和未暴露组的大脑和小脑树突密度之间没有显著差异。
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引用次数: 2
Maternal mortality risk factor in pregnancy with heart disease at Dr. Soetomo General Hospital, Surabaya, Indonesia 印度尼西亚泗水Soetomo医生综合医院妊娠合并心脏病的产妇死亡率危险因素
Pub Date : 2019-05-23 DOI: 10.20473/MOG.V1I12019.17-23
Laili Muninggar, M. Yusuf, B. Prasetyo
Objectives: This research want to identify some factors that increasing risk of maternal death in pregnant woman with heart disease.Materials and Methods: This study was a retrospective analytic study with cross sectional design, with total sampling 92 patient with heart disease in pregnancy at maternity room Dr. Soetomo hospital, Surabaya, during periode January until December 2017.Results: Prevalency of pregnancy with heart disease in dr. Soetomo hospital about 0,5% with mortality that caused by heart disease 14% from all maternal death. Factors that increase risk of maternal death are non adequate antenatal visit number (OR 1,7;CI 95%), delay of detecting heart disease (OR 2,5;CI 95%), complication such as severe pulmonal hypertension (OR 61,4;CI 95%), Eisenmenger syndrome (OR 2,9;CI 95%), Decompensatio Cordis Functional Class IV (OR 1,2;CI 95%), and Thrombo-embolism (OR 9;CI 95%).Conclusion: Mortality rate in pregnancy with heart disease is 14% of all maternal mortality. Risk of maternal death increased by non adequate antenatal visit and delay in heart disease detection, and also medical complications. Detection of heart disease since before pregnant with pre-conceptional councelling and a good managed multidisciplinary antenatal care supposed to decrease morbidity and mortality.
目的:本研究旨在确定增加心脏病孕妇孕产妇死亡风险的一些因素。材料和方法:本研究是一项横断面设计的回顾性分析研究,在2017年1月至12月期间,对泗水Soetomo医生医院产科的92名妊娠期心脏病患者进行了抽样调查。Soetomo医院约占0.5%,其中由心脏病引起的死亡率占所有孕产妇死亡的14%。增加产妇死亡风险的因素包括产前访视次数不足(OR 1,7;CI 95%)、心脏病检测延迟(OR 2,5;CI 95%。结论:妊娠合并心脏病的死亡率占孕产妇死亡率的14%。产前检查不充分、心脏病检测延迟以及医疗并发症增加了产妇死亡的风险。从怀孕前开始检测心脏病,进行孕前咨询和良好管理的多学科产前护理,以降低发病率和死亡率。
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引用次数: 5
Resurgence of placenta accreta in Indonesia 印度尼西亚胎盘增生的复苏
Pub Date : 2019-02-09 DOI: 10.20473/MOG.V26I32018.98-99
R. Aryananda
Placenta accreta is a common term used for defining a clinical condition which part or all of the placenta attaches to the myometrium that difficult to remove. Placenta accreta is a placental disorder which has been around for a long time and became a resurgence in Indonesia since 2016 with its incidence reached 2% and is still increasing until now. Placenta accreta is one of the most terrifying conditions faced by gynecologists and resulted in the increase of mortality and morbidity of pregnant women in Indonesia. In the United States, the incidence increased from less than 1 per 2000 pregnancies in 1980 to around 1 per 500 pregnancies until recently. The increased cases of placenta accreta is always directly proportional to the cesarean delivery rates.
胎盘增生是一个常用术语,用于定义部分或全部胎盘附着在子宫肌层上难以去除的临床状况。胎盘增生是一种胎盘疾病,已经存在了很长时间,自2016年以来在印度尼西亚重新兴起,其发病率达到2%,直到现在仍在增加。胎盘增生是妇科医生面临的最可怕的情况之一,导致印度尼西亚孕妇死亡率和发病率上升。在美国,发病率从1980年的每2000例妊娠中不到1例上升到最近的每500例妊娠中约1例。增生性胎盘的增加总是与剖宫产率成正比。
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引用次数: 6
Fifty percent of food restriction during gestation reduced the dendritic density of cerebrum and cerebellum of Rattus norvegicus newborn 妊娠期50%的食物限制降低了褐家鼠新生儿大脑和小脑的树突密度
Pub Date : 2019-02-09 DOI: 10.20473/MOG.V26I32018.112-117
Anwar Fauzi, W. Widjiati, H. T. Joewono
Objectives: To analyze the influence of 50 percent food  restriction during pregnancy to the dendritic density of cerebellum and cerebellum of newborn Rattus norvegicus.Materials and Methods: Laboratory experimental study with single blind randomized post-test only control group design using animal model; pregnant Rattus norvegicus as treatment models. Subjects were divided into two groups: control group and treatment group which was exposed to 50% food restriction (FR 50%). At day 21, both group sacrificed and the cerebrum and cerebelum of the offsprings were prepared and stained with silver impregnation. We used parametric independent t-test in analyzing dendritic density.Results: In the cerebrum there was a significant difference in dendritic density between control (4.98+2.17) and treatment (2.69+0.76) groups with p=0.001 (p<0.05). In the cerebellum there was ALSO a significant difference in dendritic density between control (7.37+2.23) and treatment groups (3.01+0.64) with p=0.000 (p<0.05).Conclusions: The dendritic density of cerebrum and cerebellum of newborn Rattus norvegicusexposed to 50 percent of food restriction during pregnancy  were lower than control. 
目的:分析妊娠期50%限食对新生褐家鼠小脑和小脑树突密度的影响。材料与方法:实验室实验研究采用动物模型,采用单盲随机后验组设计;妊娠褐家鼠作为治疗模型。受试者分为两组:对照组和治疗组,治疗组给予50%食物限制(FR 50%)。第21天,处死两组大鼠,制备后代的大脑和小脑,用银浸渍染色。树突密度分析采用参数独立t检验。结果:对照组(4.98+2.17)与治疗组(2.69+0.76)脑区树突密度差异有统计学意义(p<0.05);小脑树突密度对照组(7.37+2.23)与治疗组(3.01+0.64)差异有统计学意义(p<0.05)。结论:妊娠期限制50%食物的新生褐家鼠大脑和小脑树突密度均低于对照组。
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引用次数: 0
Ovarian Malignant Brenner Tumor 卵巢恶性布伦纳肿瘤
Pub Date : 2019-02-09 DOI: 10.20473/MOG.V26I32018.135-142
Romi Alfianto, A. Rahniayu, Indra Yuliati
Objectives: To report one malignant Brenner tumor (MBT) case in Dr. Soetomo Hospital, Surabaya, Indonesia, that underwent therapy from August 2016 to August 2017.Case report: A woman aged 62 years underwent total abdominal hysterectomy and bilateral salphingo-oophorectomy surgery with histopathologic results of malignant Brenner Tumor. From immunohistochemical examination the expression of p63 was positive. The patient had been treated with Paclitaxel carboplatin chemotherapy for 5-cycles, with the results of the last post-chemotherapy evaluation showing no recidive mass.Conclusion:There was only one case of malignant ovarian Brenner Tumor in Dr Soetomo Hospital, Surabaya, Indonesia, in 2014- 2016. The diagnosis can only be based on anatomic pathology examination. The specific tumor markers for malignant Brenner tumors have so far not been found.  
目的:报告2016年8月至2017年8月在印度尼西亚泗水Soetomo医生医院接受治疗的一例恶性Brenner肿瘤(MBT)病例。病例报告:一名62岁的女性接受了全腹子宫切除术和双侧输卵管卵巢切除术,并对恶性Brenner瘤的组织病理学结果进行了分析。免疫组化检测p63表达阳性。患者接受了紫杉醇-卡铂化疗5个周期,最后一次化疗后评估结果显示没有复发性肿块。结论:2014年至2016年,印度尼西亚泗水Soetomo医生医院仅有一例卵巢恶性Brenner肿瘤。诊断只能基于解剖病理检查。到目前为止,还没有发现恶性布伦纳肿瘤的特异性肿瘤标志物。
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引用次数: 1
Causes of post-caesarean surgical site infection at South Konawe Hospital, Southeast Sulawesi, Indonesia, February - July 2017 2017年2月至7月印度尼西亚苏拉威西岛东南部南科纳威医院剖宫产术后部位感染原因分析
Pub Date : 2019-02-09 DOI: 10.20473/MOG.V26I32018.118-122
M. Dani, Rizki Pranadyan, M. Yusuf, B. Prasetyo
Objectives: To analyze the causes of post-caesarean section surgical site infection (SSI) at South Konawe Hospital, Southeast Sulawesi, Indonesia, between February and July 2017.Materials and Methods: Retrospective study using descriptive method with cross-sectional design from February to July 2017 in inpatient and outpatient wards at Obstetrics and Gynecology Outpatient Clinic, South Konawe Hospital. The population was the patients medical records.Results: There were nine cases (7.75%) from totally of 116 cases of caesarean section with SSI. Based on SSI type, there were four cases (44.4%) with superficial SSI and 5 cases (55.5%) with deeper classification of SSI. SSI was dominated by women of productive age with age 20-35 years in 66.6% case. The lowest BMI was 22 kg/m2 and the highest BMI was 41.5 kg/m2. Hemoglobin levels were higher than 11 g/dL (66.6%). The most surgical action to be performed was emergency operation in 8 cases (15.09%).Conclusion:Causal characteristics of SSI at South Konawe were age of 20-35 years, the lowest BMI of 22 kg/m2 and the highest BMI 41.5 kg/m2, hemoglobin levels higher than 11 g/dL, and the need of emergency operation. 
目的:分析2017年2 - 7月印度尼西亚苏拉威西东南部南科纳威医院剖宫产术后手术部位感染(SSI)的原因。材料与方法:采用横断面设计的描述性方法对2017年2 - 7月南科纳威医院妇产科门诊住院和门诊病房进行回顾性研究。人口就是病人的医疗记录。结果:116例SSI剖宫产中有9例(7.75%)。根据SSI类型,浅表SSI 4例(44.4%),深层SSI 5例(55.5%)。66.6%的SSI病例以生育年龄妇女为主,年龄在20 ~ 35岁。最低BMI为22 kg/m2,最高BMI为41.5 kg/m2。血红蛋白水平高于11 g/dL(66.6%)。急诊手术8例(15.09%)。结论:南科纳维地区SSI发病的病因特征为年龄20 ~ 35岁,BMI最低为22 kg/m2, BMI最高为41.5 kg/m2,血红蛋白水平高于11 g/dL,需要急诊手术。
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引用次数: 0
Role of aspirin dose in reducing uterine artery resistance in 16-24 weeks pregnant women with abnormal uterine artery resistance 阿司匹林对妊娠16-24周子宫动脉阻力异常妇女降低子宫动脉阻力的作用
Pub Date : 2019-02-09 DOI: 10.20473/MOG.V26I32018.128-134
Muhammad Arief Adibrata, A. Sulistyono, E. Ernawati
Objectives: To compare the decrease of resistance index (RI) from uterine artery in pregnant woman receiving low dose aspirin therapy between 80 mg/day and 125 mg/day who had abnormal doppler velocimetry (DV) ultrasound examination at 16-24 weeks.Materials and Methods: An experimental study using double blind randomized clinical trial design. Subjects were from Mulyorejo and Kalijudan public health service in Surabaya, that included pregnant women with 16-24 weeks of pregnancy with abnormal uterine artery velocimetry ultrasound. The results of ultrasound Doppler examination were divided into four levels; normal (RI<0.58; (-) diastolic notching), level I (RI> 0.58; (-) diastolic notching), level II (RI<0.58; (+) disatolic notching) and level III (RI> 0.58; (+) diastolic notching). Uterine doppler ultrasound examination was performed at Fetomaternal Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo Hospital, Surabaya, Indonesia, by fetomaternal consultants before and after the admin-istration of low-dose aspirin of 125 mg/day and 80 mg/day for four weeks.Results: Ninety subjects were obtained and randomized into 2 groups, with 45 subject in each group. Before treatment, in 125 mg/day group those with level I were 34 subjects and level III 11 subjects. In 80 mg/day group, level I 41 subjects, level II 2 subjects and level III 2 subjects. After 4 weeks of treatment, a second DV USG was performed in Aspirin 125 mg/day group. Normal were 40 subjects, level I 4 subjects, and level III 1 subject. In aspirin group 80 mg/day, normal 22 subjects, level I 19 subjects and level III 4 subjects. The analysis was performed with Wilcoxon test before and after treatment in both aspirin treatment group 125 mg/day and 80 mg/day with p value respectively, p=0.001 and p=0.005.Conclusion: Compared with aspirin of 80 mg/day, aspirin of 125 mg/day is more superior to decrease uterine arterial resistance in pregnant women with ultrasound uterine arterial doppler velocimetry at 16-24 weeks gestational age.
目的:比较16 ~ 24周超声多普勒测速(DV)检查异常、低剂量阿司匹林80 mg/d和125 mg/d的孕妇子宫动脉阻力指数(RI)的下降情况。材料与方法:采用双盲随机临床试验设计。研究对象来自泗水市Mulyorejo和Kalijudan公共卫生服务机构,包括妊娠16-24周子宫动脉速度超声异常的孕妇。超声多普勒检查结果分为4个级别;正常(RI 0.58;(-)舒张缺口),II级(RI 0.58;(+)舒张缺口)。子宫多普勒超声检查在印度尼西亚泗水市埃尔朗加大学医学院妇产科妇产科由妇产科顾问在给予低剂量阿司匹林(125毫克/天和80毫克/天)四周前后进行。结果:获得90例受试者,随机分为2组,每组45例。治疗前,125mg /d组ⅰ级34例,ⅲ级11例。80mg /天组,ⅰ级41例,ⅱ级2例,ⅲ级2例。治疗4周后,阿司匹林125 mg/d组进行第二次DV USG。正常40例,ⅰ级4例,ⅲ级1例。阿司匹林组80mg /天,正常22例,ⅰ级19例,ⅲ级4例。采用Wilcoxon检验分析阿司匹林治疗组(125 mg/d和80 mg/d)治疗前后的差异,p值分别为p=0.001和p=0.005。结论:在16 ~ 24周孕周超声子宫动脉多普勒测速孕妇中,125 mg/d阿司匹林对降低子宫动脉阻力的效果优于80 mg/d阿司匹林。
{"title":"Role of aspirin dose in reducing uterine artery resistance in 16-24 weeks pregnant women with abnormal uterine artery resistance","authors":"Muhammad Arief Adibrata, A. Sulistyono, E. Ernawati","doi":"10.20473/MOG.V26I32018.128-134","DOIUrl":"https://doi.org/10.20473/MOG.V26I32018.128-134","url":null,"abstract":"Objectives: To compare the decrease of resistance index (RI) from uterine artery in pregnant woman receiving low dose aspirin therapy between 80 mg/day and 125 mg/day who had abnormal doppler velocimetry (DV) ultrasound examination at 16-24 weeks.Materials and Methods: An experimental study using double blind randomized clinical trial design. Subjects were from Mulyorejo and Kalijudan public health service in Surabaya, that included pregnant women with 16-24 weeks of pregnancy with abnormal uterine artery velocimetry ultrasound. The results of ultrasound Doppler examination were divided into four levels; normal (RI<0.58; (-) diastolic notching), level I (RI> 0.58; (-) diastolic notching), level II (RI<0.58; (+) disatolic notching) and level III (RI> 0.58; (+) diastolic notching). Uterine doppler ultrasound examination was performed at Fetomaternal Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo Hospital, Surabaya, Indonesia, by fetomaternal consultants before and after the admin-istration of low-dose aspirin of 125 mg/day and 80 mg/day for four weeks.Results: Ninety subjects were obtained and randomized into 2 groups, with 45 subject in each group. Before treatment, in 125 mg/day group those with level I were 34 subjects and level III 11 subjects. In 80 mg/day group, level I 41 subjects, level II 2 subjects and level III 2 subjects. After 4 weeks of treatment, a second DV USG was performed in Aspirin 125 mg/day group. Normal were 40 subjects, level I 4 subjects, and level III 1 subject. In aspirin group 80 mg/day, normal 22 subjects, level I 19 subjects and level III 4 subjects. The analysis was performed with Wilcoxon test before and after treatment in both aspirin treatment group 125 mg/day and 80 mg/day with p value respectively, p=0.001 and p=0.005.Conclusion: Compared with aspirin of 80 mg/day, aspirin of 125 mg/day is more superior to decrease uterine arterial resistance in pregnant women with ultrasound uterine arterial doppler velocimetry at 16-24 weeks gestational age.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67618163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Majalah Obstetri dan Ginekologi
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