首页 > 最新文献

Majalah Obstetri dan Ginekologi最新文献

英文 中文
Effect of prenatal Mozart composition on Brain Derived Neurotrophic Factor expression in cerebrum and cerebellum of Rattus norvegicus offspring from Food Restriction 50 model 产前莫扎特作曲对食物限制50模型褐家鼠后代大脑和小脑脑源性神经营养因子表达的影响
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.1-6
Yulia Putri Permatasari, W. Widjiati, H. T. Joewono
Objectives: To analyze the difference of BDNF expression on Rattus norvegicus offspring FR50 model in cerebrum and cerebellum between Mozart composition stimulation group and control.Materials and Methods: An analytical experimental study with single blind randomized post test only control group using animal subjects Rattus norvegicus FR50 model. This study was conducted at animal laboratory, Faculty of Veterinary Medicine, Airlangga University. Animal subjects were divided into Mozart music stimulation group and control. The BDNF expression was analyzed using comparison test, with significancy p<0,05.Results: There was no difference of BDNF expression on Rattus norvegicus offspring FR50 model between Mozart music stimu-lation group and control in cerebrum with p=0.495 (mean Mozart group 6.89+2.52 vs control 6.22+1.99), and cerebellum with p=0.146 (mean Mozart group 7.41+2.67 vs control 5.73+2.45).Conclusions: There was no difference of BDNF expression between Mozart composition stimulation group and control in the cerebrum and cerebellum of Rattus norvegicus offspring FR50 model.
目的:分析莫扎特乐曲刺激组和对照组在褐家鼠后代FR50模型大脑和小脑BDNF表达的差异。材料和方法:采用动物受试者褐家鼠FR50模型,采用单盲随机试验后对照组进行分析性实验研究。这项研究是在Airlangga大学兽医学院动物实验室进行的。实验动物分为莫扎特音乐刺激组和对照组。结果:莫扎特音乐刺激组和对照组在褐家鼠后代FR50模型脑组织BDNF表达差异无统计学意义(p=0.495,平均值为6.89±2.52,对照组为6.22±1.99),结论:在褐家鼠后代FR50模型的大脑和小脑中,莫扎特组和对照组BDNF的表达没有差异。
{"title":"Effect of prenatal Mozart composition on Brain Derived Neurotrophic Factor expression in cerebrum and cerebellum of Rattus norvegicus offspring from Food Restriction 50 model","authors":"Yulia Putri Permatasari, W. Widjiati, H. T. Joewono","doi":"10.20473/MOG.V26I12018.1-6","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.1-6","url":null,"abstract":"Objectives: To analyze the difference of BDNF expression on Rattus norvegicus offspring FR50 model in cerebrum and cerebellum between Mozart composition stimulation group and control.Materials and Methods: An analytical experimental study with single blind randomized post test only control group using animal subjects Rattus norvegicus FR50 model. This study was conducted at animal laboratory, Faculty of Veterinary Medicine, Airlangga University. Animal subjects were divided into Mozart music stimulation group and control. The BDNF expression was analyzed using comparison test, with significancy p<0,05.Results: There was no difference of BDNF expression on Rattus norvegicus offspring FR50 model between Mozart music stimu-lation group and control in cerebrum with p=0.495 (mean Mozart group 6.89+2.52 vs control 6.22+1.99), and cerebellum with p=0.146 (mean Mozart group 7.41+2.67 vs control 5.73+2.45).Conclusions: There was no difference of BDNF expression between Mozart composition stimulation group and control in the cerebrum and cerebellum of Rattus norvegicus offspring FR50 model.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48609926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effect of per oral sipermetrin exposure on serum 17 estradiol and uterine malondialdehyde (MDA) levels in female Wistar strain rats (Rattus norvegicus) 每次口服西普美林对血清17的影响 雌性Wistar品系大鼠(褐家鼠)雌二醇和子宫丙二醛(MDA)水平的变化
Pub Date : 2018-07-19 DOI: 10.20473/mog.v1i12018.20-25
Hesty Widowati, H. Sujuti, Karyono Mintaroem
Objective: This study aimed to verify the effect of oral siper-metrin exposure to decrease serum estradiol 17b levels and increased malondialdehyde (MDA) in the uterus level of female Wistar strain rats (Rattus norvegicus).Materials and Methods: The method of this study was true experimental post test only control group in vivo using 24 female rats, divided into 3 groups treated by administering a dose of 5, 10 and 20 mg/kg sipermetrin for 28 days and one control group. Then blood samples were taken from the heart for measurement of serum estradiol 17b levels by ELISA and uterine organs were taken for measurement of Malondialdehyde (MDA) with spectro-photometry method.Results: The results of the measurement of serum estradiol 17b and uterus malondialdehyde (MDA) levels of female Wistar strain rats (Rattus norvegicus) showed an opposite pattern, where there was a decline in serum estradiol 17b levels and an increase in uterus malondialdehyde (MDA) level. There was a significant difference (p=0.000
目的:本研究旨在验证口服西伯胺对雌性Wistar品系大鼠(Rattus norvegicus)血清雌二醇17b水平降低和子宫内丙二醛(MDA)水平升高的影响。材料和方法:本研究的方法是真正的实验后体内对照组,使用24只雌性大鼠,分为3组和一个对照组,分别给予5、10和20mg/kg西普美林28天。然后取心脏血样,用ELISA法测定血清雌二醇17b水平,取子宫脏器,用分光光度法测定丙二醛(MDA)。结果:雌性Wistar品系大鼠(Rattus norvegicus)血清雌二醇17b和子宫丙二醛(MDA)水平的测定结果呈相反的模式,血清雌二醇17 b水平下降,子宫丙二醛(丙二醛)水平升高。雌性大鼠17b雌二醇血清和子宫丙二醛(MDA)水平在对照组和暴露于西普美林治疗28天的组之间存在显著差异(p=0.000<α)。结论:西普霉素可降低雌性Wistar品系大鼠血清雌二醇17b水平,增加子宫丙二醛(MDA)水平。
{"title":"Effect of per oral sipermetrin exposure on serum 17 estradiol and uterine malondialdehyde (MDA) levels in female Wistar strain rats (Rattus norvegicus)","authors":"Hesty Widowati, H. Sujuti, Karyono Mintaroem","doi":"10.20473/mog.v1i12018.20-25","DOIUrl":"https://doi.org/10.20473/mog.v1i12018.20-25","url":null,"abstract":"Objective: This study aimed to verify the effect of oral siper-metrin exposure to decrease serum estradiol 17b levels and increased malondialdehyde (MDA) in the uterus level of female Wistar strain rats (Rattus norvegicus).Materials and Methods: The method of this study was true experimental post test only control group in vivo using 24 female rats, divided into 3 groups treated by administering a dose of 5, 10 and 20 mg/kg sipermetrin for 28 days and one control group. Then blood samples were taken from the heart for measurement of serum estradiol 17b levels by ELISA and uterine organs were taken for measurement of Malondialdehyde (MDA) with spectro-photometry method.Results: The results of the measurement of serum estradiol 17b and uterus malondialdehyde (MDA) levels of female Wistar strain rats (Rattus norvegicus) showed an opposite pattern, where there was a decline in serum estradiol 17b levels and an increase in uterus malondialdehyde (MDA) level. There was a significant difference (p=0.000<alpha) in 17b estradiol serum and uterus Malondialdehyde (MDA) levels of female rats between control group and group exposed to sipermetrin treatment for 28 days.Conclusions: Oral sipermetrin exposure can decrease serum levels of estradiol 17b and increase uterine levels of malondi-aldehyde (MDA) of female Wistar strain rats (Rattus norvegicus).","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46005859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of meningioma associated with exposure of hormonal contraception. A case control study 与激素避孕相关的脑膜瘤风险。病例对照研究
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.36-41
Joni Wahyuhadi, Dini Heryani, Hari Basuki
Objective: To identify the effect of hormonal contraceptive exposure to the occurrence of meningioma.Materials and Methods: This study, conducted in 2016, was a case-control study by collecting a group of cases comprising all patients diagnosed histopathologically with meningioma in 2012-2013 and treated in dr. Soetomo Hospital, Surabaya, Indonesia. Medical record data were analyzed and compared to control group of patients diagnosed with non-meningioma who underwent contrast head ct scan and direct interviews. We obtained 101 cases and 101 controls. Data were analyzed using univariate logistic regression test.Results: Based on the history of hormonal contraceptive use, patients who had history of hormonal contraceptive use had 12.31 times higher risk (p=0.000). In this study, those who had contraceptive injections for one month and used contraceptive pills had a meningioma risk lower than those who used injectables 3 months. Patients who used hormonal contraception more than 10 years had an increased risk for meningioma as much as 18.216 times (p=0.000). Histopathologically, we found a non-significant association between history of hormonal contraceptive use and the distribution of histopathology, but based on descriptive data showed it was found that the most histopatological meningioma was of the transitional type in cases group.Conclusion: There is a significant association between hormonal contraceptive use, the type of injectable hormonal contraception for 3 months, the duration of hormonal contraceptive use >10 years, and no significant association between meningioma grade and the history of hormonal contraception exposure.
目的:探讨激素避孕对脑膜瘤发生的影响。材料和方法:这项研究于2016年进行,是一项病例对照研究,收集了一组病例,包括2012-2013年组织病理学诊断为脑膜瘤并在印度尼西亚泗水Soetomo医生医院接受治疗的所有患者。对病历数据进行分析,并与接受头部ct对比扫描和直接访谈的诊断为非脑膜瘤的对照组患者进行比较。我们获得了101例病例和101例对照。数据采用单变量逻辑回归检验进行分析。结果:根据激素避孕药的使用史,有激素避孕药使用史的患者的脑膜瘤风险高12.31倍(p=0.000)。在本研究中,那些注射了一个月避孕药并使用了避孕药的患者,其脑膜瘤风险低于那些使用了3个月注射剂的患者。使用激素避孕超过10年的患者患脑膜瘤的风险增加了18.216倍(p=0.000)。在组织病理学上,我们发现激素避孕史与组织病理学分布之间没有显著关联,但根据描述性数据显示,病例组中组织病理学上最常见的脑膜瘤为移行型。结论:激素避孕的使用、3个月的注射型激素避孕的类型、激素避孕的持续时间>10年之间存在显著相关性,脑膜瘤分级与激素避孕暴露史之间没有显著相关性。
{"title":"Risk of meningioma associated with exposure of hormonal contraception. A case control study","authors":"Joni Wahyuhadi, Dini Heryani, Hari Basuki","doi":"10.20473/MOG.V26I12018.36-41","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.36-41","url":null,"abstract":"Objective: To identify the effect of hormonal contraceptive exposure to the occurrence of meningioma.Materials and Methods: This study, conducted in 2016, was a case-control study by collecting a group of cases comprising all patients diagnosed histopathologically with meningioma in 2012-2013 and treated in dr. Soetomo Hospital, Surabaya, Indonesia. Medical record data were analyzed and compared to control group of patients diagnosed with non-meningioma who underwent contrast head ct scan and direct interviews. We obtained 101 cases and 101 controls. Data were analyzed using univariate logistic regression test.Results: Based on the history of hormonal contraceptive use, patients who had history of hormonal contraceptive use had 12.31 times higher risk (p=0.000). In this study, those who had contraceptive injections for one month and used contraceptive pills had a meningioma risk lower than those who used injectables 3 months. Patients who used hormonal contraception more than 10 years had an increased risk for meningioma as much as 18.216 times (p=0.000). Histopathologically, we found a non-significant association between history of hormonal contraceptive use and the distribution of histopathology, but based on descriptive data showed it was found that the most histopatological meningioma was of the transitional type in cases group.Conclusion: There is a significant association between hormonal contraceptive use, the type of injectable hormonal contraception for 3 months, the duration of hormonal contraceptive use >10 years, and no significant association between meningioma grade and the history of hormonal contraception exposure.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42422029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Ovarian cancer with pleural and lung metastasis in Dr. Soetomo Hospital, Surabaya, Indonesia, in 2014-2015 2014-2015年印度尼西亚泗水Soetomo医生医院卵巢癌症伴胸肺转移
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.7-19
Fitria Khusnul Khotimah, A. Febriani, Pungky Mulawardhana
Objectives: To know the characteristics of ovarian cancer patients with pleural and lung metastasis, and survival rates of ovarian cancer patients with pleural and lung metastasis in Dr. Soetomo Hospital Surabaya in 2014-2015.Materials & Methods: This was a descriptive observational study using secondary data from medical records in dr. Soetomo Hospital, Surabaya, Indonesia, in 2014 and 2015Results: Number of new patients of ovarian cancer in dr. Soe-tomo, Hospital, Surabaya in 2014 was 170 patients (14%) and 122 patients (12%) in 2015. Ovarian cancer patients most often came at the stage IIIC (33.38%) with the most histopathological type was epithelial ovarian cancer. There were 5 patients with ovarian cancer with pleural metastasis and 7 patients with lung metastasis. Pleural metastasis was 80% diagnosed at the time of ovarian cancer’s diagnosis, whereas 57.15% of lung metastasis were diag-nosed >12 months after the ovarian cancer’s diagnosis. Pleural metastasis was established by pleural fluid cytology, while lung metastasis with radiological features and/or biopsies. The most common feature of lung metastasis was nodal (71.42%). Ascites was found in 80% of ovarian cancer with pleural metastasis, but only 42.86% in lung metastasis. In 2 patients receiving NAC chemotherapy and continued by interval debulking, both had negative residues. Median survival rate in ovarian cancer with pleural metastasis was 7 months, whereas in lung metastasis was 12 months.Conclusions: Number of new patients of ovarian cancer in 2014-2015 in dr. Soetomo Hospital was on rising and was the second largest number of visits after cervical cancer. In 2014-2015, there were 5 patients with ovarian cancer and pleural metastasis and 7 patients with ovarian cancer patients and lung metastasis. Median survival rate in ovarian cancer with pleural metastasis was 7 months, whereas in lung metastasis it was 12 months.
目的:了解泗水Soetomo医生医院2014-2015年卵巢癌胸膜肺转移患者的特点及胸膜肺转移患者的生存率。材料与方法:这是一项描述性观察性研究,使用了印度尼西亚泗水Soetomo医生医院2014年和2015年的病历资料。结果:2014年在泗水Soetomo医生医院新发卵巢癌患者人数为170例(14%),2015年为122例(12%)。卵巢癌患者以IIIC期居多(33.38%),组织病理类型以上皮性卵巢癌居多。卵巢癌合并胸膜转移5例,肺转移7例。在卵巢癌确诊时胸膜转移率为80%,而在卵巢癌确诊12个月后肺癌转移率为57.15%。胸膜转移可通过胸膜液细胞学检查确定,而肺转移可通过放射学特征和/或活检确定。肺转移以淋巴结转移最为常见(71.42%)。有腹水的卵巢癌伴胸膜转移者占80%,而伴肺转移者仅占42.86%。在2例接受NAC化疗并继续间歇减积的患者中,均有阴性残留物。卵巢癌胸膜转移的中位生存期为7个月,而肺转移的中位生存期为12个月。结论:2014-2015年dr. Soetomo医院卵巢癌新患者人数呈上升趋势,是仅次于宫颈癌的第二大就诊人数。2014-2015年卵巢癌合并胸膜转移5例,卵巢癌合并肺转移7例。卵巢癌胸膜转移的中位生存期为7个月,而肺转移的中位生存期为12个月。
{"title":"Ovarian cancer with pleural and lung metastasis in Dr. Soetomo Hospital, Surabaya, Indonesia, in 2014-2015","authors":"Fitria Khusnul Khotimah, A. Febriani, Pungky Mulawardhana","doi":"10.20473/MOG.V26I12018.7-19","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.7-19","url":null,"abstract":"Objectives: To know the characteristics of ovarian cancer patients with pleural and lung metastasis, and survival rates of ovarian cancer patients with pleural and lung metastasis in Dr. Soetomo Hospital Surabaya in 2014-2015.Materials & Methods: This was a descriptive observational study using secondary data from medical records in dr. Soetomo Hospital, Surabaya, Indonesia, in 2014 and 2015Results: Number of new patients of ovarian cancer in dr. Soe-tomo, Hospital, Surabaya in 2014 was 170 patients (14%) and 122 patients (12%) in 2015. Ovarian cancer patients most often came at the stage IIIC (33.38%) with the most histopathological type was epithelial ovarian cancer. There were 5 patients with ovarian cancer with pleural metastasis and 7 patients with lung metastasis. Pleural metastasis was 80% diagnosed at the time of ovarian cancer’s diagnosis, whereas 57.15% of lung metastasis were diag-nosed >12 months after the ovarian cancer’s diagnosis. Pleural metastasis was established by pleural fluid cytology, while lung metastasis with radiological features and/or biopsies. The most common feature of lung metastasis was nodal (71.42%). Ascites was found in 80% of ovarian cancer with pleural metastasis, but only 42.86% in lung metastasis. In 2 patients receiving NAC chemotherapy and continued by interval debulking, both had negative residues. Median survival rate in ovarian cancer with pleural metastasis was 7 months, whereas in lung metastasis was 12 months.Conclusions: Number of new patients of ovarian cancer in 2014-2015 in dr. Soetomo Hospital was on rising and was the second largest number of visits after cervical cancer. In 2014-2015, there were 5 patients with ovarian cancer and pleural metastasis and 7 patients with ovarian cancer patients and lung metastasis. Median survival rate in ovarian cancer with pleural metastasis was 7 months, whereas in lung metastasis it was 12 months.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46552293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nitric oxide (NO) level of the follicular fluid in endometriosis patients 子宫内膜异位症患者卵泡液一氧化氮(NO)水平
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.29-35
Cahyono Hadi, D. Dasuki, A. Sadewa, I. Astuti, Awal Prasetyo
Objectives: To ascertain the nitric oxide (NO) level of the follicular fluid of endometriosis sufferers compared with that of the non-endometriosis patients.Materials and Methods: Follicular fluid was taken from 64 women, but only 54 continued with further laboratory test. Women with endometriosis had their follicular fluid taken during laparoscopy, while the follicular fluid from non-endometriosis women was taken during tubectomy. Nitric Oxide level was analyzed using the PCR-RFLP method. Data were analyzed using software STATA Intercooled Version 11.Results: NO level in endometriosis is higher than that in non-endometriosis and has a significant relationship with all the variables (age, parity, dysmenorrhea, dyspareunia, types of endometriosis, and grade of endometriosis).Conclusion: The NO level in endometriosis is higher than that in non-endometriosis. The distribution of the polymorphism of allele GG is greater than that in non-endometriosis. The existence of polymorphism GG caused a higher eNOS, increasing NO level, causing a decrease in fertility which derived from the degenera-tive oocyte.
目的:探讨子宫内膜异位症患者与非子宫内膜异位症患者卵泡液中一氧化氮(NO)水平的差异。材料和方法:从64名妇女中提取卵泡液,但只有54名继续进行进一步的实验室检查。子宫内膜异位症患者的卵泡液在腹腔镜下采集,而非子宫内膜异位症患者的卵泡液在输卵管切除术时采集。采用PCR-RFLP法分析一氧化氮水平。数据分析使用STATA intercooling Version 11软件。结果:子宫内膜异位症患者NO水平高于非子宫内膜异位症患者,且与年龄、胎次、痛经、性交困难、子宫内膜异位症类型、子宫内膜异位症分级等因素均有显著相关。结论:子宫内膜异位症患者一氧化氮水平高于非子宫内膜异位症患者。GG等位基因多态性分布大于非子宫内膜异位症。多态性GG的存在导致eNOS升高,NO水平升高,导致卵母细胞变性导致的生育能力下降。
{"title":"Nitric oxide (NO) level of the follicular fluid in endometriosis patients","authors":"Cahyono Hadi, D. Dasuki, A. Sadewa, I. Astuti, Awal Prasetyo","doi":"10.20473/MOG.V26I12018.29-35","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.29-35","url":null,"abstract":"Objectives: To ascertain the nitric oxide (NO) level of the follicular fluid of endometriosis sufferers compared with that of the non-endometriosis patients.Materials and Methods: Follicular fluid was taken from 64 women, but only 54 continued with further laboratory test. Women with endometriosis had their follicular fluid taken during laparoscopy, while the follicular fluid from non-endometriosis women was taken during tubectomy. Nitric Oxide level was analyzed using the PCR-RFLP method. Data were analyzed using software STATA Intercooled Version 11.Results: NO level in endometriosis is higher than that in non-endometriosis and has a significant relationship with all the variables (age, parity, dysmenorrhea, dyspareunia, types of endometriosis, and grade of endometriosis).Conclusion: The NO level in endometriosis is higher than that in non-endometriosis. The distribution of the polymorphism of allele GG is greater than that in non-endometriosis. The existence of polymorphism GG caused a higher eNOS, increasing NO level, causing a decrease in fertility which derived from the degenera-tive oocyte.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43871545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of ovarian autotransplantation on FSH levels in Wistar rats late menopause model 卵巢自体移植对Wistar大鼠晚期绝经模型FSH水平的影响
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.42-47
A. Laqif, Dewi Kartika Dj Anwar, Eriana Melinawati
Objectives: To determine the effect of ovarian autotransplan-tation on decreasing FSH level in Wistarrats late menopause model.Materials and Methods: Experimental analytic research on 27 Wistar rats (Rattus novergicus) was divided into 3 groups. Group 1 (K1) or control. Group 2 (K2) performed bilateral oophorec-tomy without autotransplantation. Group 3 (K3) performed bilateral oophorectomy with autotransplantation. Measurements of FSH levels were performed on the first day, day 28 (four weeks after bilateral oophorectomy, during late menopause) and 56 day (four weeks after autotransplant). Measurement of FSH levels using ELISA. Data analysis used ANOVA and Post Hoc test.Results: The mean FSH level measured on day 56 at K1 = 63.400 ng/mL, at K2 = 78.416 ng/mL and K3 = 31.991 ng/mL. There were significant differences between K1 and K2 (p = 0,000), K1 and K3 (p = 0,000), and between K2 and K3 (p = 0,000).Conclusion: Ovarian autotransplantation decrease FSH levels in Wistar rats late menopause model.
目的:探讨卵巢自体移植对降低Wistarats绝经后模型FSH水平的影响。材料与方法:对27只Wistar大鼠(Rattus novergicus)进行实验分析研究。第1组(K1)或对照组。第2组(K2)在不进行自体移植的情况下进行双侧卵巢切除术。第3组(K3)行双侧卵巢切除术并自体移植。在第一天、第28天(双侧卵巢切除术后四周、更年期晚期)和第56天(自体移植后四周)测量FSH水平。使用ELISA测量FSH水平。数据分析采用方差分析和事后检验。结果:第56天在K1=63.400 ng/mL、K2=78.416 ng/mL和K3=31.991 ng/mL时测得的平均FSH水平。K1和K2(p=0000)、K1和K3(p=000)、K2和K3之间存在显著差异(p=10000)。
{"title":"Effect of ovarian autotransplantation on FSH levels in Wistar rats late menopause model","authors":"A. Laqif, Dewi Kartika Dj Anwar, Eriana Melinawati","doi":"10.20473/MOG.V26I12018.42-47","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.42-47","url":null,"abstract":"Objectives: To determine the effect of ovarian autotransplan-tation on decreasing FSH level in Wistarrats late menopause model.Materials and Methods: Experimental analytic research on 27 Wistar rats (Rattus novergicus) was divided into 3 groups. Group 1 (K1) or control. Group 2 (K2) performed bilateral oophorec-tomy without autotransplantation. Group 3 (K3) performed bilateral oophorectomy with autotransplantation. Measurements of FSH levels were performed on the first day, day 28 (four weeks after bilateral oophorectomy, during late menopause) and 56 day (four weeks after autotransplant). Measurement of FSH levels using ELISA. Data analysis used ANOVA and Post Hoc test.Results: The mean FSH level measured on day 56 at K1 = 63.400 ng/mL, at K2 = 78.416 ng/mL and K3 = 31.991 ng/mL. There were significant differences between K1 and K2 (p = 0,000), K1 and K3 (p = 0,000), and between K2 and K3 (p = 0,000).Conclusion: Ovarian autotransplantation decrease FSH levels in Wistar rats late menopause model.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42014874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge of pregnant women about anemia is related with adherence to iron tablets 孕妇对贫血的了解与坚持服用铁片有关
Pub Date : 2018-07-19 DOI: 10.20473/MOG.V26I12018.26-28
B. Winardi, Elga Caecaria Grahardika Andani
Objectives: to identify association between knowledge of pregnant women about anemia and the adherence to consume iron tablets in BPM Titik Suharti, Surabaya, IndonesiaMaterials and Methods: Observational analysis cross sectional study. Population consisted of 55 trimester pregnant women in BPM Titik Suharti, Surabaya, in March-April 2017. Samples were recruited using consecutive sampling. The number of sample was 35 respondents. Data were analyzed using chi-square test.Results: This research showed that all of the less knowledgeable women on anemia (100.00%) were non-adherent to consume iron tablets, almost all moderately knowledgeable women (92.9%) were adherent, and all of the fully knowledgeable women (100.00%) were adherent. Fisher exact test in significance level of 0.05 revealed p value equal to 0.0001, indicating association between knowledge about anemia and adherence to consume iron tablets at BPM Titik Suharti, Surabaya, Indonesia.Conclusion: There is an association between knowledge of pregnant women about anemia with adherence to iron tablets.
目的:了解印度尼西亚泗水苏哈提市BPM孕妇贫血知识与服用铁片依从性之间的关系。资料和方法:观察性分析横断面研究。2017年3月至4月,泗水BPM Titik Suharti的人口包括55名妊娠期孕妇。采用连续抽样的方法招募样本。样本数量为35人。数据分析采用卡方检验。结果:本研究显示,贫血知识较低的妇女(100.00%)均未坚持服用铁片,知识中等的妇女(92.9%)几乎全部坚持服用铁片,知识完全的妇女(100.00%)均坚持服用铁片。Fisher精确检验在0.05的显著性水平上显示p值等于0.0001,表明在印度尼西亚泗水的BPM Titik Suharti,关于贫血的知识与坚持服用铁片之间存在关联。结论:孕妇对贫血的了解程度与服用铁片的依从性有关。
{"title":"Knowledge of pregnant women about anemia is related with adherence to iron tablets","authors":"B. Winardi, Elga Caecaria Grahardika Andani","doi":"10.20473/MOG.V26I12018.26-28","DOIUrl":"https://doi.org/10.20473/MOG.V26I12018.26-28","url":null,"abstract":"Objectives: to identify association between knowledge of pregnant women about anemia and the adherence to consume iron tablets in BPM Titik Suharti, Surabaya, IndonesiaMaterials and Methods: Observational analysis cross sectional study. Population consisted of 55 trimester pregnant women in BPM Titik Suharti, Surabaya, in March-April 2017. Samples were recruited using consecutive sampling. The number of sample was 35 respondents. Data were analyzed using chi-square test.Results: This research showed that all of the less knowledgeable women on anemia (100.00%) were non-adherent to consume iron tablets, almost all moderately knowledgeable women (92.9%) were adherent, and all of the fully knowledgeable women (100.00%) were adherent. Fisher exact test in significance level of 0.05 revealed p value equal to 0.0001, indicating association between knowledge about anemia and adherence to consume iron tablets at BPM Titik Suharti, Surabaya, Indonesia.Conclusion: There is an association between knowledge of pregnant women about anemia with adherence to iron tablets.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41395750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
Majalah Obstetri dan Ginekologi
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1