Pub Date : 2022-12-07DOI: 10.20473/mog.v30i32022.116-121
Indiarto Wityawan, Andrijono, A. Kekalih
HIGHLIGHTS 1. The presence of Human Papillomavirus (HPV) can be detected using urine samples, as compared to cervical samples, by means of Cobas® 4800 HPV test.2. The concordance between cervical and urine samples for HPV DNA was found as much as 84.72%.3. Urine samples subjected to Cobas® 4800 HPV test is helpful to treat HPV infection. ABSTRACT Objective: To find the accuracy, sensitivity, specificity, as well as predicted values, both positive and negative, of urine samples using Cobas® 4800 in detecting high risk Human Papillomavirus. Materials and Methods: This study was a cross-sectional study with a total of 72 samples taken from medical records of hrHPV DNA examination with Cobas® 4800 in 2017-2020. Study subjects were called for re-examination of urine samples and cervical samples using Cobas® 4800. Samples with positive hrHPV DNA in the cervix, urine, or both were examined for cervical fluid-based cytology (LBC). Data were analyzed using Chi-square. Results: Overall, 84.72% agreement was detected through specimens of urine and cervical mucus tested of hrHPV DNA with Cobas® 4800. In all samples, a significant rate of concordance detection of hrHPV DNA with Cobas® 4800 was reported (ka = 0.62; 95% IC: 39-84). In this population, in determining the presence of hrHPV DNA in cervical and urine specimens, it was found that the sensitivity, specificity, positive predictive value and negative predictive value were respectively 87.5% (95% IC: 64–97%), 84% (95% IC: 72–91%), 60.9% (95% IC: 40.8–77.8%), and 96 % (95% IC: 86.3–98.9%). Conclusion: The presence of hrHPV infection in the cervix can be determined by detecting hrHPV DNA in the urine. According to these findings, urine samples subjected to the Cobas® 4800 HPV test may be helpful for the clinical treatment of HPV infection.
{"title":"Cobas® 4800 HPV test is accurate for detecting high risk Human Papillomavirus from urine samples at dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia","authors":"Indiarto Wityawan, Andrijono, A. Kekalih","doi":"10.20473/mog.v30i32022.116-121","DOIUrl":"https://doi.org/10.20473/mog.v30i32022.116-121","url":null,"abstract":"HIGHLIGHTS\u00001. The presence of Human Papillomavirus (HPV) can be detected using urine samples, as compared to cervical samples, by means of Cobas® 4800 HPV test.2. The concordance between cervical and urine samples for HPV DNA was found as much as 84.72%.3. Urine samples subjected to Cobas® 4800 HPV test is helpful to treat HPV infection.\u0000 \u0000ABSTRACT\u0000Objective: To find the accuracy, sensitivity, specificity, as well as predicted values, both positive and negative, of urine samples using Cobas® 4800 in detecting high risk Human Papillomavirus.\u0000Materials and Methods: This study was a cross-sectional study with a total of 72 samples taken from medical records of hrHPV DNA examination with Cobas® 4800 in 2017-2020. Study subjects were called for re-examination of urine samples and cervical samples using Cobas® 4800. Samples with positive hrHPV DNA in the cervix, urine, or both were examined for cervical fluid-based cytology (LBC). Data were analyzed using Chi-square.\u0000Results: Overall, 84.72% agreement was detected through specimens of urine and cervical mucus tested of hrHPV DNA with Cobas® 4800. In all samples, a significant rate of concordance detection of hrHPV DNA with Cobas® 4800 was reported (ka = 0.62; 95% IC: 39-84). In this population, in determining the presence of hrHPV DNA in cervical and urine specimens, it was found that the sensitivity, specificity, positive predictive value and negative predictive value were respectively 87.5% (95% IC: 64–97%), 84% (95% IC: 72–91%), 60.9% (95% IC: 40.8–77.8%), and 96 % (95% IC: 86.3–98.9%).\u0000Conclusion: The presence of hrHPV infection in the cervix can be determined by detecting hrHPV DNA in the urine. According to these findings, urine samples subjected to the Cobas® 4800 HPV test may be helpful for the clinical treatment of HPV infection.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87217834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-07DOI: 10.20473/mog.v30i32022.122-127
Sarah Nia Amru, Indra Yuliati, Philia Setiawan
HIGHLIGHTS 1. To provide effective prevention and management of placenta previa, maternal and neonatal outcomes should be identified.2. Among mothers studied, no maternal mortality was found, but most newborns had prematurity and low birthweight. ABSTRACT Objective: To identify maternal and neonatal outcomes in delivery with diagnosis of antepartum hemorrhage (APH) due to placenta previa. Materials and Methods: This was a descriptive retrospective study with cross-sectional design. Samples were taken using medical records with convenience sampling technique. Deliveries with history of APH due to placenta previa at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, on January 1 until December 31, 2019, were included. Results: In our study, 36 mothers were included. Maternal characteristics included age of 20–35 years in 72.2%, overweight in 50%, referral visits in 69.4%, from out of town (66.7%), bleeding onset at 3rd trimester (97.2%), primigravida (8.3%), nulliparity (13.9%), 69.4% with history of C-section, and 83.3% no hospital readmissions. Maternal outcomes included 100% mothers diagnosed with complete placenta previa and performed C-section. The mothers were mostly (69.4%) diagnosed with placenta accreta spectrum (PAS). There were 36.1% hysterectomy, 33.3% postpartum hemorrhage, 50% blood transfusions, and zero maternal mortality. Neonatal outcomes included prematurity in 80%, low birth weight (LBW) in 51.5%, while 77.1% and 85.7% of newborns had no asphyxia at 1 and 5 minutes, consecutively. Conclusion: All mothers experienced complete placenta previa, and underwent C-section with most of the mothers were diagnosed with PAS. Less than half of them needed hysterectomy intervention because other patients with focal type PAS were planned for conservative surgery. Moreover, they mostly did not have postpartum hemorrhage with half of them needed blood transfusion. There was zero maternal mortality, with most newborns experienced prematurity, LBW but no significant asphyxia.
HIGHLIGHTS1。为了提供有效的预防和管理前置胎盘，应明确孕产妇和新生儿的结局。在研究的母亲中，没有发现产妇死亡，但大多数新生儿早产和低出生体重。【摘要】目的:探讨诊断为前置胎盘所致产前出血(APH)的产妇和新生儿结局。材料与方法:本研究为横断面设计的描述性回顾性研究。样本采用病历法，采用方便取样法。纳入2019年1月1日至12月31日在印度尼西亚泗水Dr. Soetomo综合学术医院(Dr. Soetomo General Academic Hospital, Surabaya)有前置胎盘导致APH病史的分娩。结果:本研究共纳入36名母亲。产妇特征包括年龄20-35岁占72.2%，体重超重占50%，转诊占69.4%，来自外地(66.7%)，妊娠晚期出血(97.2%)，初迁(8.3%)，无产(13.9%)，有剖腹产史的69.4%，无再入院史的83.3%。产妇结局包括100%的母亲被诊断为完全性前置胎盘并进行剖腹产。多数母亲(69.4%)诊断为胎盘增生谱(PAS)。子宫切除术36.1%，产后出血33.3%，输血50%，产妇死亡率为零。新生儿结局包括早产占80%，低出生体重(LBW)占51.5%，77.1%和85.7%的新生儿连续1分钟和5分钟无窒息。结论:所有母亲都经历了完全性前置胎盘，并进行了剖腹产，大多数母亲被诊断为PAS。不到一半的患者需要子宫切除术干预，因为其他局灶型PAS患者计划进行保守手术。此外，他们大多没有产后出血，其中一半需要输血。产妇死亡率为零，大多数新生儿出现早产、LBW，但没有明显的窒息。
{"title":"Maternal and neonatal outcomes in delivery with diagnosis of antepartum hemorrhage due to placenta previa at a tertiary hospital in Surabaya, Indonesia","authors":"Sarah Nia Amru, Indra Yuliati, Philia Setiawan","doi":"10.20473/mog.v30i32022.122-127","DOIUrl":"https://doi.org/10.20473/mog.v30i32022.122-127","url":null,"abstract":"HIGHLIGHTS\u00001. To provide effective prevention and management of placenta previa, maternal and neonatal outcomes should be identified.2. Among mothers studied, no maternal mortality was found, but most newborns had prematurity and low birthweight.\u0000 \u0000ABSTRACT\u0000Objective: To identify maternal and neonatal outcomes in delivery with diagnosis of antepartum hemorrhage (APH) due to placenta previa.\u0000Materials and Methods: This was a descriptive retrospective study with cross-sectional design. Samples were taken using medical records with convenience sampling technique. Deliveries with history of APH due to placenta previa at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, on January 1 until December 31, 2019, were included.\u0000Results: In our study, 36 mothers were included. Maternal characteristics included age of 20–35 years in 72.2%, overweight in 50%, referral visits in 69.4%, from out of town (66.7%), bleeding onset at 3rd trimester (97.2%), primigravida (8.3%), nulliparity (13.9%), 69.4% with history of C-section, and 83.3% no hospital readmissions. Maternal outcomes included 100% mothers diagnosed with complete placenta previa and performed C-section. The mothers were mostly (69.4%) diagnosed with placenta accreta spectrum (PAS). There were 36.1% hysterectomy, 33.3% postpartum hemorrhage, 50% blood transfusions, and zero maternal mortality. Neonatal outcomes included prematurity in 80%, low birth weight (LBW) in 51.5%, while 77.1% and 85.7% of newborns had no asphyxia at 1 and 5 minutes, consecutively.\u0000Conclusion: All mothers experienced complete placenta previa, and underwent C-section with most of the mothers were diagnosed with PAS. Less than half of them needed hysterectomy intervention because other patients with focal type PAS were planned for conservative surgery. Moreover, they mostly did not have postpartum hemorrhage with half of them needed blood transfusion. There was zero maternal mortality, with most newborns experienced prematurity, LBW but no significant asphyxia.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77884482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-07DOI: 10.20473/mog.v30i32022.134-138
G. Gunawan, Adinda Ayu Dyah Rahadina, B. Prasetyo
HIGHLIGHTS 1. Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. 2. Comprehensive management of pregnant women with Sjögren’s syndrome was described.3. Clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy are needed by women with Sjögren’s syndrome. ABSTRACT Objective: To illustrate the comprehensive management of pregnant women with Sjögren syndrome. Case Report: A 24 years old women came to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, due to Sjögren syndrome in 35/36 weeks of gestasional age for routine examination. She was first diagnosed with Sjögren syndrome in February 2018 because she complained of dry eyes and hair fall out. This was her first pregnancy. Laboratory result showed positive ANA test. The patient had hypertension with controlled blood preasure and dry eyes. The patient was diagnosed with primigravida 35-36 weeks of pregnancy, single live intrauterine, head presentation, IUGR, screening preeclampsia was positive, and there was complication with Sjögren’s syndrome. The patient was treated by multidisciplinary team consisting of obstetricians, internists, ophthalmologists and neonatologists. Conclusion: Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. The exact cause of Sjögren's syndrome is still not known. Women with Sjögren’s syndrome should have clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy because Sjögren syndrome was a rare case during pregnancy. Close monitoring and proper management was imperative to detect the early complication.
{"title":"Comprehensive management of pregnant woman with Sjögren’s syndrome","authors":"G. Gunawan, Adinda Ayu Dyah Rahadina, B. Prasetyo","doi":"10.20473/mog.v30i32022.134-138","DOIUrl":"https://doi.org/10.20473/mog.v30i32022.134-138","url":null,"abstract":"HIGHLIGHTS\u00001. Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. 2. Comprehensive management of pregnant women with Sjögren’s syndrome was described.3. Clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy are needed by women with Sjögren’s syndrome.\u0000 \u0000ABSTRACT\u0000Objective: To illustrate the comprehensive management of pregnant women with Sjögren syndrome.\u0000Case Report: A 24 years old women came to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, due to Sjögren syndrome in 35/36 weeks of gestasional age for routine examination. She was first diagnosed with Sjögren syndrome in February 2018 because she complained of dry eyes and hair fall out. This was her first pregnancy. Laboratory result showed positive ANA test. The patient had hypertension with controlled blood preasure and dry eyes. The patient was diagnosed with primigravida 35-36 weeks of pregnancy, single live intrauterine, head presentation, IUGR, screening preeclampsia was positive, and there was complication with Sjögren’s syndrome. The patient was treated by multidisciplinary team consisting of obstetricians, internists, ophthalmologists and neonatologists.\u0000Conclusion: Sjögren’s syndrome is a chronic autoimmune disease that attacks the exocrine glands, especially lacrimal and salivary glands. The exact cause of Sjögren's syndrome is still not known. Women with Sjögren’s syndrome should have clinical and laboratory examination, risk assessment and also preconception counseling before planning pregnancy because Sjögren syndrome was a rare case during pregnancy. Close monitoring and proper management was imperative to detect the early complication.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85347289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.66-71
Elisia Atnil, A. Hestiantoro, O. Riayati, R. Febri, N. Muna
HIGHLIGHTS 1. Polycystic ovarian syndrome (PCOS) might be a condition of chronic low degree inflammation and dyslipidemia.2. Association between inflammation markers and dyslipidemia in PCOS patients was investigated.3. Dyslipidemia and chronic low degree inflammation were present in lean PCOS patients, but inflammation markers related insignificantly with dyslipidemia. ABSTRACT Objectives: This study aimed to address the detailed lipid profile in lean woman with PCOS and investigate the relationship between chronic low grade inflammation (using NLR, PLR, and monocyte/HDL ratio) and dyslipidemia (defined as total cholesterol level > 190 mg/dL). Materials and Methods: This study was a cross-sectional study conducted from June – December 2020 at the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, involving 45 women aged 18 – 35 years old, diagnosed as having PCOS with normal BMI (18.5 – 22.9 kg/m2). To compare quantitative variables, data analysis was carried out using the t-test or Mann-Whitney U test as appropriate; whereas, to compare categorical variables, the Chi-square test was used. Results: We found that although the median BMI was within normal limits at 21.48 kg/m2, the mean values of the lipid profiles were found to be either abnormal or borderline, indicating the high possibility of dyslipidemia. No statistically association between NLR, PLR and MHR with dyslipidemia. Conclusion: Dyslipidemia and chronic low-grade inflammation were found in lean PCOS subjects, but there was no significant association between inflammation markers (NLR, PLR and MHR) and dyslipidemia. Further studies should investigate other factors that cause the inflammation.
{"title":"Inflammatory markers in lean Polycystic Ovary Syndrome subjects are not associated with the spectrum of dyslipidemia","authors":"Elisia Atnil, A. Hestiantoro, O. Riayati, R. Febri, N. Muna","doi":"10.20473/mog.v30i22022.66-71","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.66-71","url":null,"abstract":"HIGHLIGHTS\u00001. Polycystic ovarian syndrome (PCOS) might be a condition of chronic low degree inflammation and dyslipidemia.2. Association between inflammation markers and dyslipidemia in PCOS patients was investigated.3. Dyslipidemia and chronic low degree inflammation were present in lean PCOS patients, but inflammation markers related insignificantly with dyslipidemia.\u0000 \u0000ABSTRACT\u0000Objectives: This study aimed to address the detailed lipid profile in lean woman with PCOS and investigate the relationship between chronic low grade inflammation (using NLR, PLR, and monocyte/HDL ratio) and dyslipidemia (defined as total cholesterol level > 190 mg/dL).\u0000Materials and Methods: This study was a cross-sectional study conducted from June – December 2020 at the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, involving 45 women aged 18 – 35 years old, diagnosed as having PCOS with normal BMI (18.5 – 22.9 kg/m2). To compare quantitative variables, data analysis was carried out using the t-test or Mann-Whitney U test as appropriate; whereas, to compare categorical variables, the Chi-square test was used.\u0000Results: We found that although the median BMI was within normal limits at 21.48 kg/m2, the mean values of the lipid profiles were found to be either abnormal or borderline, indicating the high possibility of dyslipidemia. No statistically association between NLR, PLR and MHR with dyslipidemia.\u0000Conclusion: Dyslipidemia and chronic low-grade inflammation were found in lean PCOS subjects, but there was no significant association between inflammation markers (NLR, PLR and MHR) and dyslipidemia. Further studies should investigate other factors that cause the inflammation.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81287907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.92-100
Leny Suardi, Pribakti Budinurdjaja, Wiwit Agung Sri Nurcahyawati, M. Noor
HIGHLIGHTS 1. E2 and FSH levels in menopausal women are thought to have relationship with stress urinary incontinensia (SUI).2. It was found that E2 and FSH levels had no significant relationship with SUI severity in menopausal women. ABSTRACT Objectives: This study aimed to analyze the relationship between E2 and FSH levels in menopausal women with the severity of Stress Urinary Incontinence (SUI) at Ulin Hospital, Banjarmasin, Indonesia. Materials and Methods: This study used an analytic observational method with cross-sectional design in menopausal women diagnosed with Urinary Incontinence (UI) from October 2020 - March 2021. The independent variables were E2 and FSH levels. The dependent variable was the severity of SUI in menopausal women. The severity of SUI was determined by the Incontinence Severity Index (ISI) scoring. Data were analyzed by Spearman correlation. Results: The subjects who met the criteria were 25 women. The results showed the prevalence rate of SUI was 5.8% with E2 and FSH levels of mild SUI (14.25 pg/mL and 49.70 mIU/mL), moderate (7.91 pg/mL and 54.13 mIU/mL), and severe (9.14 pg/mL) and 70.97 mIU/mL). The number of severity levels of mild SUI was 44%, moderate SUI was 48%, and severe SUI was 8%. Most patients with SUI aged >60 years, multipara, normal body mass index (BMI), duration of menopause <10 years, menarche <15 years, Intrauterine Device (IUD) contraception, and delivered with spontaneous vaginal delivery. There was no significant relationship between E2 levels and the severity of SUI with a p-value of 0.084 and a correlation coefficient of -0.353. There was no significant relationship between FSH level and severity of SUI with a p-value of 0.367 and a correlation coefficient of 0.189. Conclusion: There was no significant relationship between E2 and FSH levels and the severity of SUI in menopausal women. It is necessary to do research on other factors that influence the high severity of SUI in menopausal women.
{"title":"Impact of E2 and FSH levels on the severity of Stress Urinary Incontinence (SUI) in menopausal women","authors":"Leny Suardi, Pribakti Budinurdjaja, Wiwit Agung Sri Nurcahyawati, M. Noor","doi":"10.20473/mog.v30i22022.92-100","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.92-100","url":null,"abstract":"HIGHLIGHTS\u00001. E2 and FSH levels in menopausal women are thought to have relationship with stress urinary incontinensia (SUI).2. It was found that E2 and FSH levels had no significant relationship with SUI severity in menopausal women.\u0000 \u0000ABSTRACT\u0000Objectives: This study aimed to analyze the relationship between E2 and FSH levels in menopausal women with the severity of Stress Urinary Incontinence (SUI) at Ulin Hospital, Banjarmasin, Indonesia.\u0000Materials and Methods: This study used an analytic observational method with cross-sectional design in menopausal women diagnosed with Urinary Incontinence (UI) from October 2020 - March 2021. The independent variables were E2 and FSH levels. The dependent variable was the severity of SUI in menopausal women. The severity of SUI was determined by the Incontinence Severity Index (ISI) scoring. Data were analyzed by Spearman correlation.\u0000Results: The subjects who met the criteria were 25 women. The results showed the prevalence rate of SUI was 5.8% with E2 and FSH levels of mild SUI (14.25 pg/mL and 49.70 mIU/mL), moderate (7.91 pg/mL and 54.13 mIU/mL), and severe (9.14 pg/mL) and 70.97 mIU/mL). The number of severity levels of mild SUI was 44%, moderate SUI was 48%, and severe SUI was 8%. Most patients with SUI aged >60 years, multipara, normal body mass index (BMI), duration of menopause <10 years, menarche <15 years, Intrauterine Device (IUD) contraception, and delivered with spontaneous vaginal delivery. There was no significant relationship between E2 levels and the severity of SUI with a p-value of 0.084 and a correlation coefficient of -0.353. There was no significant relationship between FSH level and severity of SUI with a p-value of 0.367 and a correlation coefficient of 0.189.\u0000Conclusion: There was no significant relationship between E2 and FSH levels and the severity of SUI in menopausal women. It is necessary to do research on other factors that influence the high severity of SUI in menopausal women.\u0000 ","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79516398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.78-83
Muhammad Agung Khoiri, S. Lumbanraja, Duddy Aldiansyah, M. Siregar, M. Sitepu, M. Tala
HIGHLIGHTS 1. Serum calcium concentration in pregnant women who took prenatal appointments in the general hospital and its satellite hospitals were evaluated.2. It was found that serum calcium concentration in those pregnant women who made the prenatal appointments were normal. ABSTRACT Objectives: This study aimed to evaluate serum calcium concentration in pregnant women who made prenatal appointments to Obstetric and Gynecologic Outpatient Clinics at Adam Malik General Hospital, Medan, Indonesia, and its satellite hospitals. Materials and Methods: This study was a descriptive study with a case series approach. The case series of the study included 35 pregnant women in their second or third trimester chosen by consecutive sampling method. Results: The mean calcium serum level of pregnant women in the second and third trimester was 9.12±0.49 mg/dl and 8.97±0.26 mg/dl, respectively. The mean calcium level of pregnant women aged <20, 20-35, and >35 years old were 9.0±0.28 mg/dl, 9.07±0.44 mg/dl, and 8.96±0.06 mg/dl, respectively. Conclusion: This study found that the mean calcium serum level of pregnant women who took prenatal appointments in Haji Adam Malik General Hospital, Medan, Indonesia, was normal.
HIGHLIGHTS1。对在综合医院及其附属医院产前就诊的孕妇血清钙浓度进行了评价。结果发现，产前检查的孕妇血清钙浓度正常。摘要:目的:本研究旨在评估在印度尼西亚棉兰Adam Malik综合医院及其附属医院产科和妇科门诊就诊的孕妇的血清钙浓度。材料和方法:本研究为描述性研究，采用病例系列方法。本研究病例系列采用连续抽样的方法选取35例妊娠中期或晚期的孕妇。结果:妊娠中期和晚期的平均血钙水平分别为9.12±0.49 mg/dl和8.97±0.26 mg/dl。35岁孕妇的平均钙水平分别为9.0±0.28 mg/dl、9.07±0.44 mg/dl和8.96±0.06 mg/dl。结论:本研究发现，在印尼棉兰Haji Adam Malik综合医院产前就诊的孕妇平均血清钙水平正常。
{"title":"Calcium serum concentration among pregnant women in a tertiary hospital and its satellite hospital in Medan, Indonesia","authors":"Muhammad Agung Khoiri, S. Lumbanraja, Duddy Aldiansyah, M. Siregar, M. Sitepu, M. Tala","doi":"10.20473/mog.v30i22022.78-83","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.78-83","url":null,"abstract":"HIGHLIGHTS\u00001. Serum calcium concentration in pregnant women who took prenatal appointments in the general hospital and its satellite hospitals were evaluated.2. It was found that serum calcium concentration in those pregnant women who made the prenatal appointments were normal.\u0000 \u0000ABSTRACT\u0000Objectives: This study aimed to evaluate serum calcium concentration in pregnant women who made prenatal appointments to Obstetric and Gynecologic Outpatient Clinics at Adam Malik General Hospital, Medan, Indonesia, and its satellite hospitals.\u0000Materials and Methods: This study was a descriptive study with a case series approach. The case series of the study included 35 pregnant women in their second or third trimester chosen by consecutive sampling method.\u0000Results: The mean calcium serum level of pregnant women in the second and third trimester was 9.12±0.49 mg/dl and 8.97±0.26 mg/dl, respectively. The mean calcium level of pregnant women aged <20, 20-35, and >35 years old were 9.0±0.28 mg/dl, 9.07±0.44 mg/dl, and 8.96±0.06 mg/dl, respectively.\u0000Conclusion: This study found that the mean calcium serum level of pregnant women who took prenatal appointments in Haji Adam Malik General Hospital, Medan, Indonesia, was normal.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87920958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.101-107
I. G. N. A. T. Kamajaya, M. Ariyana
HIGHLIGHTS 1. Cardiovascular disease that occurs during pregnancy is the peripartum cardiomyopathy (PPCM).2. Literature on the association between preeclampsia (PE) and PPCM was reviewed.3. It was not certain whether PE is the independent risk factor of PPCM or an early predictor of PPCM development. ABSTRACT Objectives: This paper aims to review the literature related to peripartum cardiomyopathy (PPCM) and preeclampsia (PE) in order to know their frequency and relationship and the current knowledge on their pathophysiology and management. Materials and Methods: The articles reviewed in this study were primary clinical studies published around 2016 and 2021, retrieved using Google Scholar and PUBMED databases. After several evaluations, 14-full-text studies written in English were examined. Results: Overall prevalence of PE in PPCM cases varied, about 9.9% - 44% in the individual studies. The lactation hormone prolactin and placental-derived anti-angiogenic factor soluble Fms-like tyrosine kinase 1 (sFlt-1), which had been known to be able to cause cardiac dysfunction, were elevated in both PE and PPCM. This partly explained the pathophysiology that the incidence of concurrent PE in women diagnosed with PPCM was four times more than that in the general population. Conclusion: Epidemiologic studies showed significant overlap between PE and PPCM patients. However, there were not enough good quality data to fully draw conclusions about the relationship between PE and PPCM, whether PE as the independent risk factor of PPCM or an early predictor of PPCM development.
{"title":"Updated study of peripartum cardiomyopathy and preeclampsia","authors":"I. G. N. A. T. Kamajaya, M. Ariyana","doi":"10.20473/mog.v30i22022.101-107","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.101-107","url":null,"abstract":"HIGHLIGHTS\u00001. Cardiovascular disease that occurs during pregnancy is the peripartum cardiomyopathy (PPCM).2. Literature on the association between preeclampsia (PE) and PPCM was reviewed.3. It was not certain whether PE is the independent risk factor of PPCM or an early predictor of PPCM development.\u0000 \u0000ABSTRACT\u0000Objectives: This paper aims to review the literature related to peripartum cardiomyopathy (PPCM) and preeclampsia (PE) in order to know their frequency and relationship and the current knowledge on their pathophysiology and management.\u0000Materials and Methods: The articles reviewed in this study were primary clinical studies published around 2016 and 2021, retrieved using Google Scholar and PUBMED databases. After several evaluations, 14-full-text studies written in English were examined.\u0000Results: Overall prevalence of PE in PPCM cases varied, about 9.9% - 44% in the individual studies. The lactation hormone prolactin and placental-derived anti-angiogenic factor soluble Fms-like tyrosine kinase 1 (sFlt-1), which had been known to be able to cause cardiac dysfunction, were elevated in both PE and PPCM. This partly explained the pathophysiology that the incidence of concurrent PE in women diagnosed with PPCM was four times more than that in the general population.\u0000Conclusion: Epidemiologic studies showed significant overlap between PE and PPCM patients. However, there were not enough good quality data to fully draw conclusions about the relationship between PE and PPCM, whether PE as the independent risk factor of PPCM or an early predictor of PPCM development.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80590669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.58-65
Nadhif Rashesa Brahmana, A. Sa’adi, R. Yudiwati
HIGHLIGHTS 1. Infertility score should be identified to obtain successful outcome of In Vitro Fertilization (IVF).2. Factors considered in determining the infertility score were examined.3. Each factor in infertility score (e.g, age, duration of infertility, menstrual cycle, pelvic pain etc.) has its own different degrees of severity that influence the outcome of IVF. ABSTRACT Objectives: To examine the factors used in infertility score on referral and non-referral cases who underwent IVF treatment at Fertility Clinic of Graha Amerta, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2014-2016 Materials and Methods: This research was a descriptive analytic retrospective study using secondary data from medical records at Fertility Clinic of Graha Amerta in 2014-2016. With a total sampling technique, a total of 342 referral and non-referral infertility cases were obtained. The variables in this study were the factors considered in infertility score. Results: From a total of 342 cases, 44% had the wife's age in the range of 30-35 years, 80.1% had an infertile duration of > 3 years, and 54.7% had one type of pelvic pain, 68.4% still had regular menstrual cycles, and about 76% did not have a history of pelvic infection. On sperm analysis factor, there were 27.5% of men who fell into the severe category according to infertility score. There was a significant difference in the duration of infertility and sperm morphology in referral and non-referral cases. Conclusion: Infertility score can be useful because each case has its own infertility factors with different degrees of severity, which leads to infertility.
{"title":"Factors in infertility score on referral and non-referral cases who underwent In Vitro Fertilization (IVF) treatment at a fertility clinic in Surabaya, Indonesia","authors":"Nadhif Rashesa Brahmana, A. Sa’adi, R. Yudiwati","doi":"10.20473/mog.v30i22022.58-65","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.58-65","url":null,"abstract":"HIGHLIGHTS\u00001. Infertility score should be identified to obtain successful outcome of In Vitro Fertilization (IVF).2. Factors considered in determining the infertility score were examined.3. Each factor in infertility score (e.g, age, duration of infertility, menstrual cycle, pelvic pain etc.) has its own different degrees of severity that influence the outcome of IVF.\u0000 \u0000ABSTRACT\u0000Objectives: To examine the factors used in infertility score on referral and non-referral cases who underwent IVF treatment at Fertility Clinic of Graha Amerta, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2014-2016\u0000Materials and Methods: This research was a descriptive analytic retrospective study using secondary data from medical records at Fertility Clinic of Graha Amerta in 2014-2016. With a total sampling technique, a total of 342 referral and non-referral infertility cases were obtained. The variables in this study were the factors considered in infertility score.\u0000Results: From a total of 342 cases, 44% had the wife's age in the range of 30-35 years, 80.1% had an infertile duration of > 3 years, and 54.7% had one type of pelvic pain, 68.4% still had regular menstrual cycles, and about 76% did not have a history of pelvic infection. On sperm analysis factor, there were 27.5% of men who fell into the severe category according to infertility score. There was a significant difference in the duration of infertility and sperm morphology in referral and non-referral cases.\u0000Conclusion: Infertility score can be useful because each case has its own infertility factors with different degrees of severity, which leads to infertility.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82260689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-29DOI: 10.20473/mog.v30i22022.84-91
Putu Diah Ananda Putri Atmaja, Ario Danianto, T. Karuniawaty
HIGHLIGHTS 1. Clinical manifestations in pregnant and non-pregnant women with Covid-19 were identified.2. Pregnant women with Covid-19 mostly had asymptomatic clinical manifestations, while non-pregnant women with Covid-19 mostly had symptomatic clinical manifestations.3. Recognition of the clinical manifestations in pregnant women with Covid-19 may help early detection and treatment of pregnant Covid-19 patients. ABSTRACT Objectives: To know a comparison of clinical manifestations in pregnant and non-pregnant Covid-19 patients who are hospitalized at Mataram University Hospital. Materials and Methods: This study was a descriptive observational study with a cross-sectional approach, using secondary data in the form of medical records. This study uses a total sampling technique, sample selection based on affordable population, inclusion criteria, and exclusion criteria. The data was processed with SPSS 25th version and analyzed with a Chi-square analysis test. Results: In this study, it was found that 145 women confirmed Covid-19 on RT-PCR, 89 of which were pregnant and 56 others weren’t; 85.4% of the included pregnant women were in the 3rd trimester. Clinical manifestations in pregnant women are 73.0% asymptomatic while symptomatic in 60.7% of the non-pregnant women. In symptomatic pregnant women, most common clinical symptoms were nausea, vomiting, cough, and headache; while the most common clinical symptoms in non-pregnant women were cough, anosmia, and headache. Chi-square analysis test showed a significant relationship with p = 0.000 (p < 0.05) in clinical manifestation comparison. Conclusion: There are differences in clinical manifestations in pregnant and non-pregnant women with Covid-19. The most common clinical manifestation in pregnant women was asymptomatic and in non-pregnant women the most common clinical manifestation was symptomatic.
{"title":"Clinical manifestations comparison in hospitalized pregnant and non-pregnant women with Covid-19 at Mataram University Hospital, Mataram, Indonesia","authors":"Putu Diah Ananda Putri Atmaja, Ario Danianto, T. Karuniawaty","doi":"10.20473/mog.v30i22022.84-91","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.84-91","url":null,"abstract":"HIGHLIGHTS\u00001. Clinical manifestations in pregnant and non-pregnant women with Covid-19 were identified.2. Pregnant women with Covid-19 mostly had asymptomatic clinical manifestations, while non-pregnant women with Covid-19 mostly had symptomatic clinical manifestations.3. Recognition of the clinical manifestations in pregnant women with Covid-19 may help early detection and treatment of pregnant Covid-19 patients.\u0000 \u0000ABSTRACT\u0000Objectives: To know a comparison of clinical manifestations in pregnant and non-pregnant Covid-19 patients who are hospitalized at Mataram University Hospital.\u0000Materials and Methods: This study was a descriptive observational study with a cross-sectional approach, using secondary data in the form of medical records. This study uses a total sampling technique, sample selection based on affordable population, inclusion criteria, and exclusion criteria. The data was processed with SPSS 25th version and analyzed with a Chi-square analysis test.\u0000Results: In this study, it was found that 145 women confirmed Covid-19 on RT-PCR, 89 of which were pregnant and 56 others weren’t; 85.4% of the included pregnant women were in the 3rd trimester. Clinical manifestations in pregnant women are 73.0% asymptomatic while symptomatic in 60.7% of the non-pregnant women. In symptomatic pregnant women, most common clinical symptoms were nausea, vomiting, cough, and headache; while the most common clinical symptoms in non-pregnant women were cough, anosmia, and headache. Chi-square analysis test showed a significant relationship with p = 0.000 (p < 0.05) in clinical manifestation comparison.\u0000Conclusion: There are differences in clinical manifestations in pregnant and non-pregnant women with Covid-19. The most common clinical manifestation in pregnant women was asymptomatic and in non-pregnant women the most common clinical manifestation was symptomatic.\u0000 ","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77142250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIGHLIGHTS 1. Visual Inspection with Acetic Acid (VIA) method is used in midwifery for early detection of cervical cancer.2. Service period, knowledge, and attitudes are factors that affect a midwife's performance in using VIA method for cervical cancer detection. ABSTRACT Objective: This study examined the association between service period, knowledge, and attitudes toward the performance of midwives in the early detection of cervical cancer using the Visual Inspection with Acetic Acid (VIA) method in Banjarmasin, Indonesia. Materials and Methods: This is a cross-sectional study done in 26 Public Health Centers in Banjarmasin, Indonesia, from March to November 2020 involving 172 respondents. Samples were purposively selected using a non-probability sampling technique. Data collection instruments were questionnaire and Health Service reports. Data analysis was done computerized. Results: Out of 172 respondents, 67.4% of which had > 10 years of service period, 67.4% had inadequate knowledge and 86% showed a positive attitude about early detection of cervical cancer using the IVA method, and 79.9% had poor performance in conducting early detection of cervical cancer using the IVA method. Results of Chi-square test showed the associations between the service period (p = 0.005), knowledge (p = 0.0001), and attitude (p = 0.005) with the performance of midwives in early detection of cervical cancer using the VIA method. Conclusion: Service period, knowledge, and attitudes were associated with the performance of midwives in the early detection of cervical cancer using the VIA method in Banjarmasin, Indonesia. Professional training programs should be taken into consideration in improving the performance of midwives in cervical cancer detection.
{"title":"The performance of midwives in early detection of cervical cancer using visual inspection test with acetic acid","authors":"Deviati Juwita Sari, Pudji Lestari, Pungky Mulawardhana","doi":"10.20473/mog.v30i22022.52-57","DOIUrl":"https://doi.org/10.20473/mog.v30i22022.52-57","url":null,"abstract":"HIGHLIGHTS\u00001. Visual Inspection with Acetic Acid (VIA) method is used in midwifery for early detection of cervical cancer.2. Service period, knowledge, and attitudes are factors that affect a midwife's performance in using VIA method for cervical cancer detection.\u0000 \u0000ABSTRACT\u0000Objective: This study examined the association between service period, knowledge, and attitudes toward the performance of midwives in the early detection of cervical cancer using the Visual Inspection with Acetic Acid (VIA) method in Banjarmasin, Indonesia.\u0000Materials and Methods: This is a cross-sectional study done in 26 Public Health Centers in Banjarmasin, Indonesia, from March to November 2020 involving 172 respondents. Samples were purposively selected using a non-probability sampling technique. Data collection instruments were questionnaire and Health Service reports. Data analysis was done computerized.\u0000Results: Out of 172 respondents, 67.4% of which had > 10 years of service period, 67.4% had inadequate knowledge and 86% showed a positive attitude about early detection of cervical cancer using the IVA method, and 79.9% had poor performance in conducting early detection of cervical cancer using the IVA method. Results of Chi-square test showed the associations between the service period (p = 0.005), knowledge (p = 0.0001), and attitude (p = 0.005) with the performance of midwives in early detection of cervical cancer using the VIA method.\u0000Conclusion: Service period, knowledge, and attitudes were associated with the performance of midwives in the early detection of cervical cancer using the VIA method in Banjarmasin, Indonesia. Professional training programs should be taken into consideration in improving the performance of midwives in cervical cancer detection.","PeriodicalId":52893,"journal":{"name":"Majalah Obstetri dan Ginekologi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90971334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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