Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-08-139
John Bamigboye, S. Olateju, A. Faponle, A. Salako
Background: Prostate biopsy is a painful procedure, and the degree of pain is related to the number of core biopsies taken. Objective: To compare the analgesic properties of hyperbaric bupivacaine 0.25% with 0.375% ropivacaine for saddle block in transrectal prostate biopsy. Methods: This was a randomised double-blinded study. Eighty patients with indications for prostate biopsy presenting at the Day-Case Theatre in a Nigerian tertiary facility were randomised into two equal groups: B (Bupivacaine) and R (Ropivacaine). Group B received 1ml of 0.25% bupivacaine, while Group R received 1ml of 0.375% ropivacaine for saddle block, respectively. Pain assessment, home readiness, patients' satisfaction, and time to first analgesic request were assessed and compared between the two groups. Results: The Bupivacaine group had an earlier onset of sensory block (11.90±4.10 minutes vs 23.70±8.65 minutes, p = 0.000), slower sensory block regression (48.73±9.32 minutes vs 24.88±4.21 minutes, p = 0.000), but delayed home readiness (47.23±15.93 minutes vs 29.88±8.58 minutes, p = 0.000), than patients in the Ropivacaine group. The pain scores during, immediately after and 30 minutes post-biopsy were lower in the Bupivacaine group: p = 0.010, p = 0.028 and p = 0.023 respectively. The time to first analgesic request was also longer in the Bupivacaine group (48.73±9.33 minutes) than for those in the Ropivacaine group (24.88±4.21 minutes) with statistical significance (p = 0.000). Conclusion: Intraoperative analgesic properties were better in the Bupivacaine group than in the Ropivacaine group. However, home readiness was earlier in the Ropivacaine group.
背景：前列腺活检是一种痛苦的过程，疼痛程度与核心活检的数量有关。目的：比较0.25%高压布比卡因和0.375%罗哌卡因用于鞍式阻滞经直肠前列腺活检的镇痛效果。方法：这是一项随机双盲研究。在尼日利亚一家三级医院的Day Case Theatre，80名前列腺活检适应症患者被随机分为两组：B组（布比卡因）和R组（罗哌卡因）。B组接受0.25%布比卡因1ml，R组接受0.375%罗哌卡因1ml用于鞍区阻滞。对两组患者的疼痛评估、家庭准备情况、患者满意度和首次镇痛请求时间进行评估和比较。结果：与罗哌卡因组相比，布比卡因组的感觉阻滞发作较早（11.90±4.10分钟vs 23.70±8.65分钟，p=0.000），感觉阻滞消退较慢（48.73±9.32分钟vs 24.88±4.21分钟，p=0.0000），但回家准备延迟（47.23±15.93分钟vs 29.88±8.58分钟，p=0.00）。布比卡因组在活检期间、活检后即刻和活检后30分钟的疼痛评分较低：分别为p=0.010、p=0.028和p=0.023。布比卡因组首次镇痛时间（48.73±9.33分钟）也长于罗哌卡因组（24.88±4.21分钟），具有统计学意义（p=0.000）。然而，罗哌卡因组的回家准备时间较早。
{"title":"Saddle Block for Transrectal Prostate Biopsy: A Comparison of the Analgesic Efficacy of 0.25% Bupivacaine and 0.375% Ropivacaine","authors":"John Bamigboye, S. Olateju, A. Faponle, A. Salako","doi":"10.30442/ahr.0703-08-139","DOIUrl":"https://doi.org/10.30442/ahr.0703-08-139","url":null,"abstract":"Background: Prostate biopsy is a painful procedure, and the degree of pain is related to the number of core biopsies taken. \u0000Objective: To compare the analgesic properties of hyperbaric bupivacaine 0.25% with 0.375% ropivacaine for saddle block in transrectal prostate biopsy. \u0000Methods: This was a randomised double-blinded study. Eighty patients with indications for prostate biopsy presenting at the Day-Case Theatre in a Nigerian tertiary facility were randomised into two equal groups: B (Bupivacaine) and R (Ropivacaine). Group B received 1ml of 0.25% bupivacaine, while Group R received 1ml of 0.375% ropivacaine for saddle block, respectively. Pain assessment, home readiness, patients' satisfaction, and time to first analgesic request were assessed and compared between the two groups. \u0000Results: The Bupivacaine group had an earlier onset of sensory block (11.90±4.10 minutes vs 23.70±8.65 minutes, p = 0.000), slower sensory block regression (48.73±9.32 minutes vs 24.88±4.21 minutes, p = 0.000), but delayed home readiness (47.23±15.93 minutes vs 29.88±8.58 minutes, p = 0.000), than patients in the Ropivacaine group. The pain scores during, immediately after and 30 minutes post-biopsy were lower in the Bupivacaine group: p = 0.010, p = 0.028 and p = 0.023 respectively. The time to first analgesic request was also longer in the Bupivacaine group (48.73±9.33 minutes) than for those in the Ropivacaine group (24.88±4.21 minutes) with statistical significance (p = 0.000). \u0000Conclusion: Intraoperative analgesic properties were better in the Bupivacaine group than in the Ropivacaine group. However, home readiness was earlier in the Ropivacaine group.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49165963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-09-140
K. Oritogun, O. Oyewole
Background: Stroke is one of the major public health problems worldwide. Physical and mental health data of stroke survivors are often expressed in proportions. Therefore, the Beta Regression models family for data between zero and one will be appropriate. Objectives: To identify a suitable model and the likely risk factors of physical and mental health of stroke survivors. Method: Secondary data of stroke survivors from two tertiary health Institutions in Ogun State, Nigeria, were analysed. Inflated Beta (BEINF) and Inflated-at-one-Beta (BEINF1) models were compared using Deviance (DEV), Akaike Information Criterion (AIC) and Bayesian Information Criteria (BIC) for model selection. The model with minimum DEV, AIC and BIC was considered to be better. Results: The deviance (-86.0604,), AIC (-46.0604) and BIC (6.4391) values of the BEINF1 model for physical health and the deviance (-20.1217), AIC (19.8783) and BIC (72.3778) values of BEINF1 model for mental health were smaller than BEINF models. Therefore, BEINF1 was the better model to identify the health risk factors of stroke survivors. Age, marital status, diastolic blood pressure, disability duration and systolic blood pressure had a significant association with physical health, while BMI had a significant positive association with mental health. Conclusion: The beta-inflated-at-one (BEINF1) model is suitable for identifying health risk factors of stroke survivors when the outcome variable is a proportion. Both demographic and clinical characteristics were significantly associated with the health of stroke survivors. This study would assist researchers in knowing the appropriate model for analysing proportion or percentage response variables.
{"title":"Beta Inflated Regression Models on the Physical and Mental Health of Nigerian Stroke Survivors","authors":"K. Oritogun, O. Oyewole","doi":"10.30442/ahr.0703-09-140","DOIUrl":"https://doi.org/10.30442/ahr.0703-09-140","url":null,"abstract":"Background: Stroke is one of the major public health problems worldwide. Physical and mental health data of stroke survivors are often expressed in proportions. Therefore, the Beta Regression models family for data between zero and one will be appropriate. \u0000Objectives: To identify a suitable model and the likely risk factors of physical and mental health of stroke survivors. \u0000Method: Secondary data of stroke survivors from two tertiary health Institutions in Ogun State, Nigeria, were analysed. Inflated Beta (BEINF) and Inflated-at-one-Beta (BEINF1) models were compared using Deviance (DEV), Akaike Information Criterion (AIC) and Bayesian Information Criteria (BIC) for model selection. The model with minimum DEV, AIC and BIC was considered to be better. \u0000Results: The deviance (-86.0604,), AIC (-46.0604) and BIC (6.4391) values of the BEINF1 model for physical health and the deviance (-20.1217), AIC (19.8783) and BIC (72.3778) values of BEINF1 model for mental health were smaller than BEINF models. Therefore, BEINF1 was the better model to identify the health risk factors of stroke survivors. Age, marital status, diastolic blood pressure, disability duration and systolic blood pressure had a significant association with physical health, while BMI had a significant positive association with mental health. \u0000Conclusion: The beta-inflated-at-one (BEINF1) model is suitable for identifying health risk factors of stroke survivors when the outcome variable is a proportion. Both demographic and clinical characteristics were significantly associated with the health of stroke survivors. This study would assist researchers in knowing the appropriate model for analysing proportion or percentage response variables.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43514943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-01-130
PO Olatunji
Research is an effort to seek the truth and communicate it. In the process, participants or subjects of research must be recognised and respected, and the principles of research ethics must protect the vulnerable from exploitation. The researcher must do the reporting of research findings with honesty and professionalism. Non-adherence to the above principles in the early research period resulted in gross abuse of personality and autonomy. Research is now subjected to rigorous scrutiny to stem the tide of abuse and ascertain and guarantee the sanctity of the research participants, process and product. These are the fundamentals of the practice of ethics in both research and publication. In effect, this paper aims to address ethics and its application to research and publications.
{"title":"Research and Publication Ethics","authors":"PO Olatunji","doi":"10.30442/ahr.0703-01-130","DOIUrl":"https://doi.org/10.30442/ahr.0703-01-130","url":null,"abstract":"Research is an effort to seek the truth and communicate it. In the process, participants or subjects of research must be recognised and respected, and the principles of research ethics must protect the vulnerable from exploitation. The researcher must do the reporting of research findings with honesty and professionalism. Non-adherence to the above principles in the early research period resulted in gross abuse of personality and autonomy. Research is now subjected to rigorous scrutiny to stem the tide of abuse and ascertain and guarantee the sanctity of the research participants, process and product. These are the fundamentals of the practice of ethics in both research and publication. In effect, this paper aims to address ethics and its application to research and publications.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44755561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-03-132
Sorely C Bello, R. Ibraheem, A. Saka
Background: The sucking habits of infants can be nutritive and non-nutritive sucking. Digit-sucking is normal in babies and young children, but sometimes it may persist into early childhood. Objective: To determine the burden, knowledge and belief of mothers/caregivers concerning digit sucking among under-five children. Methods: A cross-sectional study involving children under the age of 5 years attending the University of Ilorin Teaching Hospital, Ilorin, Nigeria, was conducted. The mothers of selected children were surveyed using an interviewer-administered questionnaire. Results: The prevalence of non-nutritive digit sucking was 45.8%. While 68 (43.9%) of these children sucked their digits, 3 (1.9%) sucked pacifiers. The thumb and two digits were the preferred digits (52.9%). Sucking was done while awake in 36 (52.9%) children while 32 (47.1%) sucked whether awake or sleeping. Most (60.3%) mothers have the wrong perception of digit sucking and had attempted to discourage it. Conclusions: The prevalence of non-nutritive and digit sucking was high in the population studied. Sucking occurs while awake and asleep, both day and night. Most mothers have the wrong perception of digit sucking and had attempted its stoppage.
{"title":"Knowledge of Non-nutritive Digit Sucking Among Mothers of Under-Five Children in Ilorin, Nigeria","authors":"Sorely C Bello, R. Ibraheem, A. Saka","doi":"10.30442/ahr.0703-03-132","DOIUrl":"https://doi.org/10.30442/ahr.0703-03-132","url":null,"abstract":"Background: The sucking habits of infants can be nutritive and non-nutritive sucking. Digit-sucking is normal in babies and young children, but sometimes it may persist into early childhood. \u0000Objective: To determine the burden, knowledge and belief of mothers/caregivers concerning digit sucking among under-five children. \u0000Methods: A cross-sectional study involving children under the age of 5 years attending the University of Ilorin Teaching Hospital, Ilorin, Nigeria, was conducted. The mothers of selected children were surveyed using an interviewer-administered questionnaire. \u0000Results: The prevalence of non-nutritive digit sucking was 45.8%. While 68 (43.9%) of these children sucked their digits, 3 (1.9%) sucked pacifiers. The thumb and two digits were the preferred digits (52.9%). Sucking was done while awake in 36 (52.9%) children while 32 (47.1%) sucked whether awake or sleeping. Most (60.3%) mothers have the wrong perception of digit sucking and had attempted to discourage it. \u0000Conclusions: The prevalence of non-nutritive and digit sucking was high in the population studied. Sucking occurs while awake and asleep, both day and night. Most mothers have the wrong perception of digit sucking and had attempted its stoppage.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70070913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-04-133
O. Oduwole, J. Mwankon, J. Okebe, Ekpereonne Esu, M. Chibuzor, A. Sallahdeen, D. Arikpo, C. Meremikwu, E. Effa, M. Meremikwu
Background: The Bacille Calmette-Guérin (BCG) vaccine, given as a single dose, offers variable protection against Tuberculosis (TB). It is plausible that repeat doses could improve the effectiveness of the BCG vaccine in settings where the population remain at risk of the disease. Objective: To assess the effectiveness of BCG revaccination as a booster dose in preventing TB in Low- and Middle- Income Countries (LMICs). Methods: We searched the electronic databases without language or publication restrictions and followed the procedures for preparing systematic reviews, including assessing the risk of bias as outlined in the Cochrane handbook. We included randomised controlled trials (RCTs) conducted in LMICs involving children and adults receiving one or more BCG vaccine doses after the primary BCG vaccination. The incidence of severe forms of TB, active TB and adverse events were the primary outcomes. Results: Five RCTs were included in this systematic review. Revaccination with BCG probably makes little or no difference to the risk of active TB measured after five years (Relative risk (RR) 1.16, 95% CI 0.88 to 1.51; 348,083 participants; one study, moderate certainty evidence) or nine years post-revaccination (RR 0.96, 95% CI 0.82 to 1.12; 348,083 participants; one study, moderate certainty evidence). In populations with HIV co-infection, revaccination probably increases the risk of pulmonary tuberculosis compared to placebo (RR 1.74, 95% CI 1.00 to 3.01; 46,764 participants; one study, moderate certainty evidence). Conclusion: The available evidence suggests that BCG revaccination probably makes little or no difference in preventing tuberculosis disease in LMICs.
{"title":"Booster Dose of Bacille Calmette-Guérin Vaccine for Tuberculosis in Low and Middle-Income Countries: A Systematic Review","authors":"O. Oduwole, J. Mwankon, J. Okebe, Ekpereonne Esu, M. Chibuzor, A. Sallahdeen, D. Arikpo, C. Meremikwu, E. Effa, M. Meremikwu","doi":"10.30442/ahr.0703-04-133","DOIUrl":"https://doi.org/10.30442/ahr.0703-04-133","url":null,"abstract":"Background: The Bacille Calmette-Guérin (BCG) vaccine, given as a single dose, offers variable protection against Tuberculosis (TB). It is plausible that repeat doses could improve the effectiveness of the BCG vaccine in settings where the population remain at risk of the disease. \u0000Objective: To assess the effectiveness of BCG revaccination as a booster dose in preventing TB in Low- and Middle- Income Countries (LMICs). \u0000Methods: We searched the electronic databases without language or publication restrictions and followed the procedures for preparing systematic reviews, including assessing the risk of bias as outlined in the Cochrane handbook. We included randomised controlled trials (RCTs) conducted in LMICs involving children and adults receiving one or more BCG vaccine doses after the primary BCG vaccination. The incidence of severe forms of TB, active TB and adverse events were the primary outcomes. \u0000Results: Five RCTs were included in this systematic review. Revaccination with BCG probably makes little or no difference to the risk of active TB measured after five years (Relative risk (RR) 1.16, 95% CI 0.88 to 1.51; 348,083 participants; one study, moderate certainty evidence) or nine years post-revaccination (RR 0.96, 95% CI 0.82 to 1.12; 348,083 participants; one study, moderate certainty evidence). In populations with HIV co-infection, revaccination probably increases the risk of pulmonary tuberculosis compared to placebo (RR 1.74, 95% CI 1.00 to 3.01; 46,764 participants; one study, moderate certainty evidence). \u0000Conclusion: The available evidence suggests that BCG revaccination probably makes little or no difference in preventing tuberculosis disease in LMICs.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41577834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-05-136
A. Ladele, J. Ogunkoya, C. Elikwu, T. Oyedele, K. Tuta, O. Abiodun, A. Idowu, S. Eigbe
Background: Healthcare workers (HCWs) are at high risk of contracting and spreading the novel Coronavirus Disease 2019 (COVID-19) disease putting themselves, the patients and the community at large at risk. Therefore, there is a need for adequate preparedness in the face of this pandemic. Objectives: To assess the knowledge of HCW (clinical and non-clinical) on COVID-19, determine the level of HCWs preparedness against COVID-19 and evaluate the level of preparedness of the hospital facility against COVID-19. Methods: Purposive sampling technique was used in this cross-sectional study. A self-administered questionnaire adapted from a validated questionnaire was used to collect appropriate data on socio-demographics, knowledge about COVID 19 and preparedness. Results: A total of 170 HCWs with a mean age of 34.7±6.9 years participated in this study. More than half (56.5%; 96/170) were females. The average knowledge score among clinical staff was 9.04±13.77, with 80 clinical staff having good knowledge of COVID-19. The majority of non-clinical staff had a fair knowledge of COVID-19 with an average knowledge score of 5.11±47.07. About 63.4% were not confident enough in caring for a suspected coronavirus case even though more than half (57.6%) have had formal training in Infection Prevention and Control and above 77% (131/170) confirmed the availability of PPE in their facility. However, about three-quarters (74.7%; 127/170) believed the hospital is well prepared to manage COVID-19 cases. Conclusion: This study revealed that this cohort of HCWs have good knowledge of COVID-19 and are convinced that they and their facility are well prepared for outbreaks of COVID-19.
{"title":"Awareness and Preparedness for the Ongoing Community Spread of Coronavirus Infections Among Healthcare Workers in a Nigerian Private Tertiary Facility","authors":"A. Ladele, J. Ogunkoya, C. Elikwu, T. Oyedele, K. Tuta, O. Abiodun, A. Idowu, S. Eigbe","doi":"10.30442/ahr.0703-05-136","DOIUrl":"https://doi.org/10.30442/ahr.0703-05-136","url":null,"abstract":"Background: Healthcare workers (HCWs) are at high risk of contracting and spreading the novel Coronavirus Disease 2019 (COVID-19) disease putting themselves, the patients and the community at large at risk. Therefore, there is a need for adequate preparedness in the face of this pandemic. \u0000Objectives: To assess the knowledge of HCW (clinical and non-clinical) on COVID-19, determine the level of HCWs preparedness against COVID-19 and evaluate the level of preparedness of the hospital facility against COVID-19. \u0000Methods: Purposive sampling technique was used in this cross-sectional study. A self-administered questionnaire adapted from a validated questionnaire was used to collect appropriate data on socio-demographics, knowledge about COVID 19 and preparedness. \u0000Results: A total of 170 HCWs with a mean age of 34.7±6.9 years participated in this study. More than half (56.5%; 96/170) were females. The average knowledge score among clinical staff was 9.04±13.77, with 80 clinical staff having good knowledge of COVID-19. The majority of non-clinical staff had a fair knowledge of COVID-19 with an average knowledge score of 5.11±47.07. About 63.4% were not confident enough in caring for a suspected coronavirus case even though more than half (57.6%) have had formal training in Infection Prevention and Control and above 77% (131/170) confirmed the availability of PPE in their facility. However, about three-quarters (74.7%; 127/170) believed the hospital is well prepared to manage COVID-19 cases. \u0000Conclusion: This study revealed that this cohort of HCWs have good knowledge of COVID-19 and are convinced that they and their facility are well prepared for outbreaks of COVID-19.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44875762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-11-142
I. Awowole, OA Adeniyi, O. Allen, A. Adeyemi
Cervical Ectopic Pregnancies (CEPs) are commonly associated with adverse outcomes due to diagnostic and treatment challenges. This report describes the successful management of an initially misdiagnosed CEP. A 30-year-old G4P2+1(Alive 2) presented to the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria, with vaginal bleeding following 11 weeks amenorrhea. The patient was haemodynamically stable, with minimal bleeding per vaginam, and ultrasonography had previously diagnosed complete miscarriage. However, transvaginal ultrasonography demonstrated classical hour-glass uterus. The ballooned cervix contained a gestational sac and foetal node without cardiac activity. The patient was managed with a single dose of intramuscular methotrexate injection. Her serum B-HCG concentration declined from 460.8mIU/ml at presentation to <5mIU/ml on the 10th day post-methotrexate injection, with a complete clinical and ultrasonographic resolution of the features. A high index of suspicion and appropriate ultrasonographic skills are necessary for prompt diagnosis of a CEP. Medical management could minimise the risk of intractable haemorrhage and hysterectomy.
{"title":"Fertility-preserving Management of Cervical Ectopic Pregnancy in a Nigerian Teaching Hospital","authors":"I. Awowole, OA Adeniyi, O. Allen, A. Adeyemi","doi":"10.30442/ahr.0703-11-142","DOIUrl":"https://doi.org/10.30442/ahr.0703-11-142","url":null,"abstract":"Cervical Ectopic Pregnancies (CEPs) are commonly associated with adverse outcomes due to diagnostic and treatment challenges. This report describes the successful management of an initially misdiagnosed CEP. A 30-year-old G4P2+1(Alive 2) presented to the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Nigeria, with vaginal bleeding following 11 weeks amenorrhea. The patient was haemodynamically stable, with minimal bleeding per vaginam, and ultrasonography had previously diagnosed complete miscarriage. However, transvaginal ultrasonography demonstrated classical hour-glass uterus. The ballooned cervix contained a gestational sac and foetal node without cardiac activity. The patient was managed with a single dose of intramuscular methotrexate injection. Her serum B-HCG concentration declined from 460.8mIU/ml at presentation to <5mIU/ml on the 10th day post-methotrexate injection, with a complete clinical and ultrasonographic resolution of the features. A high index of suspicion and appropriate ultrasonographic skills are necessary for prompt diagnosis of a CEP. Medical management could minimise the risk of intractable haemorrhage and hysterectomy.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41478603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-06-137
A. Ahmed, O. Ojo, M. Saka, G. Salaudeen
Background: Clients’ satisfaction surveys are required to identify gaps and challenges in providing healthcare services; to ensure the quality of care and patient satisfaction. Objectives: To compare and assess factors responsible for healthcare satisfaction among rural and urban communities in Ilorin East Local Government Area (LGA) of Kwara State to improve service provision among the communities. Methods: This was a comparative, cross-sectional study involving rural (250) and urban (250) respondents selected through a multi-stage sampling technique and surveyed using an interviewer-administered questionnaire. Focus Group Discussion was also used to collect qualitative data. Participants were selected through the purposive sampling technique. Results: The proportion of clients who expressed satisfaction was 172 (68.8%) among urban and 175 (70.0%) among rural respondents, (z = 0.57; p = 0.45). The attitude of healthcare personnel influenced satisfaction among both the rural (56.0%) and urban (63.3%) respondents, respectively; short waiting time (12.8%) and privacy of the consulting rooms (13.7%) were reasons influencing satisfaction with service. Conclusion: Short waiting time and privacy of consulting room were reasons for service satisfaction among clients. Waiting time was a strong predictor of satisfaction. There is a need to improve health personnel’s attitude to work to ensure clients’ satisfaction with healthcare services.
{"title":"Rural-Urban Disparities and Factors Associated with Clients’ Satisfaction with Healthcare in a Nigerian population","authors":"A. Ahmed, O. Ojo, M. Saka, G. Salaudeen","doi":"10.30442/ahr.0703-06-137","DOIUrl":"https://doi.org/10.30442/ahr.0703-06-137","url":null,"abstract":"Background: Clients’ satisfaction surveys are required to identify gaps and challenges in providing healthcare services; to ensure the quality of care and patient satisfaction. \u0000Objectives: To compare and assess factors responsible for healthcare satisfaction among rural and urban communities in Ilorin East Local Government Area (LGA) of Kwara State to improve service provision among the communities. \u0000Methods: This was a comparative, cross-sectional study involving rural (250) and urban (250) respondents selected through a multi-stage sampling technique and surveyed using an interviewer-administered questionnaire. Focus Group Discussion was also used to collect qualitative data. Participants were selected through the purposive sampling technique. \u0000Results: The proportion of clients who expressed satisfaction was 172 (68.8%) among urban and 175 (70.0%) among rural respondents, (z = 0.57; p = 0.45). The attitude of healthcare personnel influenced satisfaction among both the rural (56.0%) and urban (63.3%) respondents, respectively; short waiting time (12.8%) and privacy of the consulting rooms (13.7%) were reasons influencing satisfaction with service. \u0000Conclusion: Short waiting time and privacy of consulting room were reasons for service satisfaction among clients. Waiting time was a strong predictor of satisfaction. There is a need to improve health personnel’s attitude to work to ensure clients’ satisfaction with healthcare services.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45000626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-02-131
I. Ezeani, A. Eregie, A. Ohwovoriole
Recent reports from Cardiovascular Outcome Trials (CVOTs) revealed that some newer anti-diabetic drugs impact Major Adverse Cardiovascular Events (MACE). These medications include the Sodium-Glucose Co-Transporter (SGLT2) inhibitors and the Glucagon-like Peptide-1 (GLP-1) receptor agonists. There is a need for a review of the mechanisms of action of these drugs, in addition to their glucose-lowering effects and CV benefits. This review paper aims to explore the cardio-protective effects and CV risks of anti-diabetic medications, their mechanisms of action and the CV benefits evidenced by CVOTs. Using internet search, with search items such as Type 2 Diabetes mellitus, cardiovascular risk factors, cardiovascular outcome trials, major adverse cardiovascular events, sodium-glucose transporter-2 inhibitors, glucagon-like peptide-1 receptor agonist, the Google Scholar, EMBASE, PubMed, Medline, Web MD, and Scopus were checked for various relevant published articles. Analyses of the results of multiple CVOTs from various parts of the world were considered. These CVOTs were reviewed to assess the role of anti-diabetic agents in reducing cardiovascular risk in patients with T2DM. The SGLT2 inhibitors and GLP1 agonists were found to be beneficial in lowering MACE when compared with placebo. This is in addition to their anti-hyperglycaemic benefits. In conclusion, SGLT2 inhibitors and GLP-1 agonists confer dramatic beneficial CV risk reduction on patients with T2DM, as shown by the various CVOTs. This is in addition to their anti-hyperglycaemic effects. This remarkable benefit justifies the need by various guidelines to adopt them as second line agents to metformin in managing patients with T2DM.
{"title":"Anti-diabetic Agents and the Potentials for Reducing Cardiovascular Risks in Type-2 Diabetes Mellitus","authors":"I. Ezeani, A. Eregie, A. Ohwovoriole","doi":"10.30442/ahr.0703-02-131","DOIUrl":"https://doi.org/10.30442/ahr.0703-02-131","url":null,"abstract":"Recent reports from Cardiovascular Outcome Trials (CVOTs) revealed that some newer anti-diabetic drugs impact Major Adverse Cardiovascular Events (MACE). These medications include the Sodium-Glucose Co-Transporter (SGLT2) inhibitors and the Glucagon-like Peptide-1 (GLP-1) receptor agonists. There is a need for a review of the mechanisms of action of these drugs, in addition to their glucose-lowering effects and CV benefits. This review paper aims to explore the cardio-protective effects and CV risks of anti-diabetic medications, their mechanisms of action and the CV benefits evidenced by CVOTs. Using internet search, with search items such as Type 2 Diabetes mellitus, cardiovascular risk factors, cardiovascular outcome trials, major adverse cardiovascular events, sodium-glucose transporter-2 inhibitors, glucagon-like peptide-1 receptor agonist, the Google Scholar, EMBASE, PubMed, Medline, Web MD, and Scopus were checked for various relevant published articles. Analyses of the results of multiple CVOTs from various parts of the world were considered. These CVOTs were reviewed to assess the role of anti-diabetic agents in reducing cardiovascular risk in patients with T2DM. The SGLT2 inhibitors and GLP1 agonists were found to be beneficial in lowering MACE when compared with placebo. This is in addition to their anti-hyperglycaemic benefits. \u0000In conclusion, SGLT2 inhibitors and GLP-1 agonists confer dramatic beneficial CV risk reduction on patients with T2DM, as shown by the various CVOTs. This is in addition to their anti-hyperglycaemic effects. This remarkable benefit justifies the need by various guidelines to adopt them as second line agents to metformin in managing patients with T2DM.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48384836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-27DOI: 10.30442/ahr.0703-10-141
M. Kundra, S. Sood, SP Gulia, N. Sharma
Background: The knowledge of the incidence of blood Transfusion Transmissible Infections (TTIs) such as Hepatitis B, Hepatitis C, Human Immunodeficiency Virus infection, malaria and syphilis is essential for monitoring the safety of blood supply. Objective: To describe the prevalence of TTIs for monitoring blood supply safety and evaluating the efficacy of screening procedures. Methods: A five-year retrospective study spanning January 2016 to December 2020 was carried out on voluntary blood donors at blood donation camps organised by Adesh Medical College and Hospital, Kurukshetra, Haryana, India, and from donors at the hospital’s blood bank. The donated blood was tested for Hepatitis-B, Hepatitis-C, Human Immunodeficiency Virus (HIV), malaria and syphilis. Results: There were a total of 10,468 voluntary blood donors during the period of study. Out of all the donors, 0.4% tested positive for at least one of the TTIs, including 0.06% testing positive for HIV, 0.21% for Hepatitis-B virus (HBV) infection (Hepatitis-B Surface Antigen) and 0.13% for Hepatitis-C virus (HCV) infection (Anti HCV Antibodies). None of the voluntary donors was positive for malaria or syphilis. There were no co-infections. Conclusions: The prevalence of TTIs among voluntary blood donors was low hence the advocation for blood from this group of donors. Donated blood specimens should be more effectively screened, and blood should be rationally used.
{"title":"Seroprevalence of Transfusion Transmissible Infections Among Voluntary Blood Donors at an Indian Hospital","authors":"M. Kundra, S. Sood, SP Gulia, N. Sharma","doi":"10.30442/ahr.0703-10-141","DOIUrl":"https://doi.org/10.30442/ahr.0703-10-141","url":null,"abstract":"Background: The knowledge of the incidence of blood Transfusion Transmissible Infections (TTIs) such as Hepatitis B, Hepatitis C, Human Immunodeficiency Virus infection, malaria and syphilis is essential for monitoring the safety of blood supply. \u0000Objective: To describe the prevalence of TTIs for monitoring blood supply safety and evaluating the efficacy of screening procedures. \u0000Methods: A five-year retrospective study spanning January 2016 to December 2020 was carried out on voluntary blood donors at blood donation camps organised by Adesh Medical College and Hospital, Kurukshetra, Haryana, India, and from donors at the hospital’s blood bank. The donated blood was tested for Hepatitis-B, Hepatitis-C, Human Immunodeficiency Virus (HIV), malaria and syphilis. \u0000Results: There were a total of 10,468 voluntary blood donors during the period of study. Out of all the donors, 0.4% tested positive for at least one of the TTIs, including 0.06% testing positive for HIV, 0.21% for Hepatitis-B virus (HBV) infection (Hepatitis-B Surface Antigen) and 0.13% for Hepatitis-C virus (HCV) infection (Anti HCV Antibodies). None of the voluntary donors was positive for malaria or syphilis. There were no co-infections. \u0000Conclusions: The prevalence of TTIs among voluntary blood donors was low hence the advocation for blood from this group of donors. Donated blood specimens should be more effectively screened, and blood should be rationally used.","PeriodicalId":52960,"journal":{"name":"Annals of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47215183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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