In the first half of 2020 the world population was hit by a Novel Coronavirus outbreak that leads to severe acute respiratory syndrome, which later named as COVID-19. The countries soon started to report their first cases and in March the COVID-19 which was initially declared as a public health emergency then later declared as a pandemic by World Health Organization (WHO). The fear generated as a result of the pandemic among the people has many antecedents. The aim of this study was to find out the hypothesized relationship between the generated fear and the exaggeration of the media about pandemic, as well as to look at whether communication from health professionals, family and friends mediates this relationship. According to the results of the analysis which has been carried out by the data collected by questionnaire, there is a positive and strong relationship between all three variables. Additionally, mediation analysis showed that the relationship between exaggeration of media and generation of fear is mediated by the communication by health professionals, friends and family meaning that communication plays an important role in terms of generated fear.
{"title":"The Mediator Role of Communication about COVID-19 on the Relationship between Exaggeration of Media and Generated Fear: Case of North Cyprus","authors":"Ayşen Berberoğlu, A. Dinler","doi":"10.29333/jcei/9281","DOIUrl":"https://doi.org/10.29333/jcei/9281","url":null,"abstract":"In the first half of 2020 the world population was hit by a Novel Coronavirus outbreak that leads to severe acute respiratory syndrome, which later named as COVID-19. The countries soon started to report their first cases and in March the COVID-19 which was initially declared as a public health emergency then later declared as a pandemic by World Health Organization (WHO). The fear generated as a result of the pandemic among the people has many antecedents. The aim of this study was to find out the hypothesized relationship between the generated fear and the exaggeration of the media about pandemic, as well as to look at whether communication from health professionals, family and friends mediates this relationship. According to the results of the analysis which has been carried out by the data collected by questionnaire, there is a positive and strong relationship between all three variables. Additionally, mediation analysis showed that the relationship between exaggeration of media and generation of fear is mediated by the communication by health professionals, friends and family meaning that communication plays an important role in terms of generated fear.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48877303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anwarul Karim, T. Banu, Mastura Akter, A. Mazid, O. S. Pulock, T. T. Aziz, Samira Hayee, Nowrin Tamanna, GS Chuwdhury, A. Haque, Farhana Yeasmin, M. A. Mitu, F. Yeasmin, H. Rashid, Ashish Kumar Kuri, Arni Das, Koushik Majumder, Dipen Barua, M. Rahaman, S. Akter, Nashid Niaz Munia, Jabin Sultana, Faeeqa Usaila, Sabrina Sifat, N. Nourin, Md. Forhad Uddin, M. Bhowmik, T. Ahammed, N. Sharik, Quddus Mehnaz, Md. Nur Hossain Bhuiyan
Aim: This study investigated the knowledge and attitudes towards COVID-19 in Bangladeshi adults by online and phone survey methods during the early stage of its spread. Methods: Data were collected through phone calls (April 14-23, 2020) and online survey (April 18-19, 2020) in Bangladesh. The questionnaire had 20 knowledge questions with each correct response getting one point and incorrect/don’t know response getting no point (maximum total knowledge score 20). Participants scoring >17 were categorized as having good knowledge. Results: The percentages of good knowledge holders were 57.6%, 75.1%, and 95.8% in the phone, online non-medical, and online medical participants, respectively. Most of the phone and online participants had good knowledge of the preventive practices of COVID-19. However, among the non-medical participants (both phone and online), the correct response rates were lower than 80% for the knowledge questions asking about the facts that - some patients may have no symptoms, diarrhea is a symptom of this disease and that it cannot be prevented by any currently available medication. Male gender, higher education, living in town/urban areas, good financial condition, and use of internet were positively associated with higher knowledge score among the non-medical participants. However, higher knowledge score was associated with having less confidence in the final control of COVID-19. Conclusion: Our study identified some COVID-19 information that were less known among the participants and the potential factors that were associated with having good versus poor knowledge. Besides, this study sheds light on the attitude of Bangladeshi adults towards COVID-19.
{"title":"Knowledge and Attitude towards COVID-19: A Cross Sectional Study in Bangladesh through Phone and Online Survey","authors":"Anwarul Karim, T. Banu, Mastura Akter, A. Mazid, O. S. Pulock, T. T. Aziz, Samira Hayee, Nowrin Tamanna, GS Chuwdhury, A. Haque, Farhana Yeasmin, M. A. Mitu, F. Yeasmin, H. Rashid, Ashish Kumar Kuri, Arni Das, Koushik Majumder, Dipen Barua, M. Rahaman, S. Akter, Nashid Niaz Munia, Jabin Sultana, Faeeqa Usaila, Sabrina Sifat, N. Nourin, Md. Forhad Uddin, M. Bhowmik, T. Ahammed, N. Sharik, Quddus Mehnaz, Md. Nur Hossain Bhuiyan","doi":"10.29333/jcei/9143","DOIUrl":"https://doi.org/10.29333/jcei/9143","url":null,"abstract":"Aim: This study investigated the knowledge and attitudes towards COVID-19 in Bangladeshi adults by online and phone survey methods during the early stage of its spread.\u0000Methods: Data were collected through phone calls (April 14-23, 2020) and online survey (April 18-19, 2020) in Bangladesh. The questionnaire had 20 knowledge questions with each correct response getting one point and incorrect/don’t know response getting no point (maximum total knowledge score 20). Participants scoring >17 were categorized as having good knowledge.\u0000Results: The percentages of good knowledge holders were 57.6%, 75.1%, and 95.8% in the phone, online non-medical, and online medical participants, respectively. Most of the phone and online participants had good knowledge of the preventive practices of COVID-19. However, among the non-medical participants (both phone and online), the correct response rates were lower than 80% for the knowledge questions asking about the facts that - some patients may have no symptoms, diarrhea is a symptom of this disease and that it cannot be prevented by any currently available medication. Male gender, higher education, living in town/urban areas, good financial condition, and use of internet were positively associated with higher knowledge score among the non-medical participants. However, higher knowledge score was associated with having less confidence in the final control of COVID-19.\u0000Conclusion: Our study identified some COVID-19 information that were less known among the participants and the potential factors that were associated with having good versus poor knowledge. Besides, this study sheds light on the attitude of Bangladeshi adults towards COVID-19.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49513939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electronegative Low-density Lipoprotein (L5) may be Associated with the Severity of COVID-19","authors":"S. Akyol, F. Armutcu","doi":"10.29333/jcei/8565","DOIUrl":"https://doi.org/10.29333/jcei/8565","url":null,"abstract":"","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46016807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Treatment and post-treatment rehabilitation of COVID-19, which first appeared in Wuhan, China at the end of 2019, causing hundreds of thousands of people to die, has become very important for both patients and scientists. Some chronic health problems, especially in healing patients, have led to the emergence of alternative treatment methods. Significant studies have been conducted on COVID-19 triggering chronic respiratory diseases in patients recovered because of the effects on the respiratory tract. In some studies, it was found that individuals who recovered could not use the functions of the lung with their pre-disease capacity. Halotherapy, which is a treatment method applying by be delivered a fine powder to the upper part of the lower respiratory tract of a person, is a natural and reliable therapy method for respiratory infections, asthma, allergic and chronic bronchitis, colds, pharyngitis, rhinitis, tonsillitis, chronic obstructive pulmonary disease, and various skin diseases. Halotherapy has an important place in alternative medicine. Many studies have been carried out on the benefit of Halotherapy, which is considered both Salt Therapy and Cave Therapy, in chronic respiratory diseases. In this context, it is considered that Halotherapy can be useful in the treatment of chronic respiratory diseases of individuals with COVID-19 disease in our study based on these studies. Also, scientific studies are recommended treating patients with COVID-19 in areas where salt therapy and speleotherapy are involved in the treatment of chronic respiratory diseases.
{"title":"The Importance of Halotherapy in the Treatment of COVID-19 Related Diseases","authors":"B. Uysal, Ebrar Ulusinan","doi":"10.29333/jcei/8486","DOIUrl":"https://doi.org/10.29333/jcei/8486","url":null,"abstract":"Treatment and post-treatment rehabilitation of COVID-19, which first appeared in Wuhan, China at the end of 2019, causing hundreds of thousands of people to die, has become very important for both patients and scientists. Some chronic health problems, especially in healing patients, have led to the emergence of alternative treatment methods. Significant studies have been conducted on COVID-19 triggering chronic respiratory diseases in patients recovered because of the effects on the respiratory tract. In some studies, it was found that individuals who recovered could not use the functions of the lung with their pre-disease capacity. Halotherapy, which is a treatment method applying by be delivered a fine powder to the upper part of the lower respiratory tract of a person, is a natural and reliable therapy method for respiratory infections, asthma, allergic and chronic bronchitis, colds, pharyngitis, rhinitis, tonsillitis, chronic obstructive pulmonary disease, and various skin diseases. Halotherapy has an important place in alternative medicine. Many studies have been carried out on the benefit of Halotherapy, which is considered both Salt Therapy and Cave Therapy, in chronic respiratory diseases. In this context, it is considered that Halotherapy can be useful in the treatment of chronic respiratory diseases of individuals with COVID-19 disease in our study based on these studies. Also, scientific studies are recommended treating patients with COVID-19 in areas where salt therapy and speleotherapy are involved in the treatment of chronic respiratory diseases.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47129390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-06DOI: 10.31487/J.CEI.2020.02.07
C. Verma, Suresh K. Patel, Gayatri S. Jere, R. Bhadade
Coronavirus disease-19 (COVID-19) has affected people of various age groups with symptoms ranging from asymptomatic or mild to severe respiratory failure, with mild symptoms requiring little or no medical intervention whereas severe symptoms requiring hospitalisation and prompt medical management. The following case report illustrates about recovery of a patient with severe symptoms of COVID-19 in a COVID dedicated tertiary care hospital run by the Municipal Corporation of Greater Mumbai. Physiotherapy has long been a part of multidisciplinary team in management of patients with severe respiratory illnesses. The report mainly presents about the Physiotherapy management undertaken for the above-mentioned patient parallelly to the Medical management aiding in recovery of the patient.
{"title":"Physiotherapy Management of a Middle-Aged Adult Male with Severe Symptoms of Coronavirus Disease-19: A Case Report","authors":"C. Verma, Suresh K. Patel, Gayatri S. Jere, R. Bhadade","doi":"10.31487/J.CEI.2020.02.07","DOIUrl":"https://doi.org/10.31487/J.CEI.2020.02.07","url":null,"abstract":"Coronavirus disease-19 (COVID-19) has affected people of various age groups with symptoms ranging\u0000from asymptomatic or mild to severe respiratory failure, with mild symptoms requiring little or no medical\u0000intervention whereas severe symptoms requiring hospitalisation and prompt medical management. The\u0000following case report illustrates about recovery of a patient with severe symptoms of COVID-19 in a\u0000COVID dedicated tertiary care hospital run by the Municipal Corporation of Greater Mumbai.\u0000Physiotherapy has long been a part of multidisciplinary team in management of patients with severe\u0000respiratory illnesses. The report mainly presents about the Physiotherapy management undertaken for the\u0000above-mentioned patient parallelly to the Medical management aiding in recovery of the patient.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83157070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-14DOI: 10.1101/2020.07.10.20151258
F. Rahal, Salima Rezak, F. Z. B. Hamed
Several studies have confirmed the impact of weather conditions on the evolution of the Covid-19 pandemic. We wanted to verify this phenomenon in the city of Oran in Algeria, which experienced its first case of Covid19 on March 19, 2020. The data studied are the new Covid19 cases, the average, minimum and maximum temperatures, as well as the relative humidity rate. A first analysis of the data with a Spearman rank correlation test did not yield significant results. Taking into account the average incubation period to adjust the data made it possible, during a second analysis, to show that the minimum temperature is significantly correlated with the new cases of Covid19 in Oran. This study can help establish prevention policies against Covid19, especially during fall in temperatures in autumn and winter.
{"title":"Impact of meteorological parameters on the Covid-19 incidence. The case of the city of Oran, Algeria.","authors":"F. Rahal, Salima Rezak, F. Z. B. Hamed","doi":"10.1101/2020.07.10.20151258","DOIUrl":"https://doi.org/10.1101/2020.07.10.20151258","url":null,"abstract":"Several studies have confirmed the impact of weather conditions on the evolution of the Covid-19 pandemic. We wanted to verify this phenomenon in the city of Oran in Algeria, which experienced its first case of Covid19 on March 19, 2020. The data studied are the new Covid19 cases, the average, minimum and maximum temperatures, as well as the relative humidity rate. A first analysis of the data with a Spearman rank correlation test did not yield significant results. Taking into account the average incubation period to adjust the data made it possible, during a second analysis, to show that the minimum temperature is significantly correlated with the new cases of Covid19 in Oran. This study can help establish prevention policies against Covid19, especially during fall in temperatures in autumn and winter.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41339985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In developing countries, emergences of the infectious diseases cause serious issues to public health security due to lack of sufficient resources The emergence of the COVID-2019 in China during late December 2019 resulted in international health emergency all over the world in few weeks and attained high risk category On 11 March 2020, World Health Organization declared Coronavirus disease as pandemic Staring from Wuhan, China, coronavirus disease has spread in 209 countries including Pakistan Till March 30, 2020, the number of causalities by Coronavirus disease has reached up to 33,983 among 722664 confirmed cases affected by this globally In Pakistan, the first case of the Coronavirus is reported on February 25, 2020 and till 30 March 2020, 1526 confirmed cases and 13 deaths are reported by Ministry of National Health Services of Pakistan The fight of Pakistan against coronavirus disease like other developing countries may be different from technologically equipped countries Despite of the limited recourses, Pakistan has taken meticulous measures by developing special hospitals on pattern of Republic of China, availability of rapid diagnosis, strict implementation of lockdown and strong awareness campaign against COVID-19 This article reviews recent outbreak of COVID-19 and its trends of control measures taken by Government of Pakistan for development of nimble health care setup in the country [ABSTRACT FROM AUTHOR] Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
{"title":"COVID-19 in Pakistan: Current Scenario and Future Perspective","authors":"N. Akhtar","doi":"10.29333/jcei/8354","DOIUrl":"https://doi.org/10.29333/jcei/8354","url":null,"abstract":"In developing countries, emergences of the infectious diseases cause serious issues to public health security due to lack of sufficient resources The emergence of the COVID-2019 in China during late December 2019 resulted in international health emergency all over the world in few weeks and attained high risk category On 11 March 2020, World Health Organization declared Coronavirus disease as pandemic Staring from Wuhan, China, coronavirus disease has spread in 209 countries including Pakistan Till March 30, 2020, the number of causalities by Coronavirus disease has reached up to 33,983 among 722664 confirmed cases affected by this globally In Pakistan, the first case of the Coronavirus is reported on February 25, 2020 and till 30 March 2020, 1526 confirmed cases and 13 deaths are reported by Ministry of National Health Services of Pakistan The fight of Pakistan against coronavirus disease like other developing countries may be different from technologically equipped countries Despite of the limited recourses, Pakistan has taken meticulous measures by developing special hospitals on pattern of Republic of China, availability of rapid diagnosis, strict implementation of lockdown and strong awareness campaign against COVID-19 This article reviews recent outbreak of COVID-19 and its trends of control measures taken by Government of Pakistan for development of nimble health care setup in the country [ABSTRACT FROM AUTHOR] Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48133846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
More than a third of the world population is currently under some form of partial or total lockdown to limit morbidity and mortality due to covid-19. Whereas these measures are working, they are exerting an unprecedented negative socio-economic impact on the general wellbeing, and thus may not be sustained for long. Alternative control measures that limit the spread of the virus and yet facilitate socioeconomic progression and wellbeing are urgent. In this article, we make suggestions based on the disease transmission characteristics, the World Health Organization recommendation, and current practices across the globe. The suggestions focus on the prevention of transmission and acquisition by; (1) ensuring all put on some form of protective barriers to prevent further spread and acquisition while in public or risky spaces, (2) proactively preventing contamination of surfaces at individual and group/community level, (3) disinfecting frequently all surfaces prone to contamination in public and private spaces (4) ensuring that all gathering, work, schools and other public places have COVID-19 prevention protocols in place and are followed, (5) developing an efficient surveillance system that ensures early detection and isolation of COVID-19 cases, (6) strengthening health facilities at all levels of the healthcare system to ably screen, test, isolate, and manage COVID-19 before complications set in, (7) Stepping up health education and awareness at population level on prevention measures for COVID-19 using all possible platforms, (8) Designing special prevention measures for congested neighborhoods and slum dwellings, care homes, and other institutionalized dwellings to prevent a surge in infection and catastrophes, and finally (9) strengthening national, regional and global collaboration to prevent cross-border transmission. A combination of several of the measures above should help ease lockdown and moreover sustain the gains in the absence of the vaccine – thus, ease the consequences of strict social distancing, travel bans and lockdown across settings.
{"title":"The COVID-19 Lockdown Trap, How do we get out?","authors":"G. Musinguzi, B. Asamoah","doi":"10.29333/jcei/8343","DOIUrl":"https://doi.org/10.29333/jcei/8343","url":null,"abstract":"More than a third of the world population is currently under some form of partial or total lockdown to limit morbidity and mortality due to covid-19. Whereas these measures are working, they are exerting an unprecedented negative socio-economic impact on the general wellbeing, and thus may not be sustained for long. Alternative control measures that limit the spread of the virus and yet facilitate socioeconomic progression and wellbeing are urgent. In this article, we make suggestions based on the disease transmission characteristics, the World Health Organization recommendation, and current practices across the globe. The suggestions focus on the prevention of transmission and acquisition by; (1) ensuring all put on some form of protective barriers to prevent further spread and acquisition while in public or risky spaces, (2) proactively preventing contamination of surfaces at individual and group/community level, (3) disinfecting frequently all surfaces prone to contamination in public and private spaces (4) ensuring that all gathering, work, schools and other public places have COVID-19 prevention protocols in place and are followed, (5) developing an efficient surveillance system that ensures early detection and isolation of COVID-19 cases, (6) strengthening health facilities at all levels of the healthcare system to ably screen, test, isolate, and manage COVID-19 before complications set in, (7) Stepping up health education and awareness at population level on prevention measures for COVID-19 using all possible platforms, (8) Designing special prevention measures for congested neighborhoods and slum dwellings, care homes, and other institutionalized dwellings to prevent a surge in infection and catastrophes, and finally (9) strengthening national, regional and global collaboration to prevent cross-border transmission. A combination of several of the measures above should help ease lockdown and moreover sustain the gains in the absence of the vaccine – thus, ease the consequences of strict social distancing, travel bans and lockdown across settings.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45715557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. A. Baba, A. Kharbach, A. Achbani, A. Naciri, Youssef Bouchriti, H. Sine
In March 2020, the WHO declared COVID-19 as a pandemic. At present, the curative vaccine has not yet been developed. Early detection and efficient control of the route of transmission are still the most effective way to fight the COVID-19 outbreak. Patients with confirmed COVID-19 pneumonia have typical imaging features that can be helpful in early screening of highly suspected cases and in evaluation of the severity and extent of disease.
{"title":"Imaging Profile of the COVID-19 Infection: A Narrative Overview","authors":"M. A. Baba, A. Kharbach, A. Achbani, A. Naciri, Youssef Bouchriti, H. Sine","doi":"10.29333/jcei/8319","DOIUrl":"https://doi.org/10.29333/jcei/8319","url":null,"abstract":"In March 2020, the WHO declared COVID-19 as a pandemic. At present, the curative vaccine has not yet been developed. Early detection and efficient control of the route of transmission are still the most effective way to fight the COVID-19 outbreak. Patients with confirmed COVID-19 pneumonia have typical imaging features that can be helpful in early screening of highly suspected cases and in evaluation of the severity and extent of disease.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41329955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-29DOI: 10.31487/j.cei.2020.01.01
D. Sweetman, J. Plewa, M. Nguyen, V. Kimonis
Background: IBMPFD (Inclusion Body Myopathy associated with Paget disease of the bone and Frontotemporal Dementia) is an autosomal dominant inherited disease caused by VCP gene mutations. Very little natural history data exists on this disease. We report a patient with a significant family history of IBMPFD associated with the common R155H mutation in the VCP gene. Objective: This study will address the lack of long-term data for muscle strength, and respiratory function in IBMPFD. The hypothesis is that detailed analysis in a single patient will provide meaningful natural history data in IBMPFD, a progressive neurodegenerative disease. Method: Regression analysis was performed across multiple parameters related to myopathy including dynamometry, MRC scale, IBM functional rating scale, pulmonary function studies and sleep quality. Results: Measurements of this patient highlight progressive generalized weakness in proximal and distal regions, decline in pulmonary function, and asymmetrical strength differences of the upper extremities. Measurements over five years revealed an overall deterioration with a slope of -1.13 and R2 value of 0.77. Conclusion: This unique data derived from long-term evaluations in a patient provides the first report of the rate of progression of muscle weakness and pulmonary function deterioration in VCP associated inclusion body myopathy.
{"title":"A Natural History Study of VCP Associated Vacuolar Myopathy in a Patient with the Common R155H Mutation","authors":"D. Sweetman, J. Plewa, M. Nguyen, V. Kimonis","doi":"10.31487/j.cei.2020.01.01","DOIUrl":"https://doi.org/10.31487/j.cei.2020.01.01","url":null,"abstract":"Background: IBMPFD (Inclusion Body Myopathy associated with Paget disease of the bone and\u0000Frontotemporal Dementia) is an autosomal dominant inherited disease caused by VCP gene mutations. Very\u0000little natural history data exists on this disease. We report a patient with a significant family history of\u0000IBMPFD associated with the common R155H mutation in the VCP gene.\u0000Objective: This study will address the lack of long-term data for muscle strength, and respiratory function\u0000in IBMPFD. The hypothesis is that detailed analysis in a single patient will provide meaningful natural\u0000history data in IBMPFD, a progressive neurodegenerative disease.\u0000Method: Regression analysis was performed across multiple parameters related to myopathy including\u0000dynamometry, MRC scale, IBM functional rating scale, pulmonary function studies and sleep quality.\u0000Results: Measurements of this patient highlight progressive generalized weakness in proximal and distal\u0000regions, decline in pulmonary function, and asymmetrical strength differences of the upper extremities.\u0000Measurements over five years revealed an overall deterioration with a slope of -1.13 and R2 value of 0.77.\u0000Conclusion: This unique data derived from long-term evaluations in a patient provides the first report of\u0000the rate of progression of muscle weakness and pulmonary function deterioration in VCP associated\u0000inclusion body myopathy.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76800168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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