首页 > 最新文献

Journal of Clinical and Experimental Investigations最新文献

英文 中文
Awareness of Neural Tube Defects in Family Physicians 家庭医生对神经管缺陷的认识
Pub Date : 2021-02-13 DOI: 10.29333/JCEI/9707
Izzet Goker Kucuk, Utku Eser, Murat Çevik, K. Ongel
Objective: The aim of this study was to measure the knowledge level of physicians working in family health centers about the conditions leading to neural tube defect (NTD) and preventive measures.Material and Methods: In this cross-sectional study, 406 general practitioners and family medicine specialists made a survey consisted of 13 questions. Chi-square, Fisher’s Exact test and Pearson chi-square analysis were applied as statistical methods.Results: A total of 406 physicians (family medicine specialists: 110, general practitioners: 296) participated in the study. 81.53% of the participants were working in a city and 18.47% were working in the countryside. The number of referral to general practitioners before pregnancy was significantly higher than that of family medicine specialists. (p<0.05). 36.95% of the respondents knew that the neural tube was closed in the first month of embryological life. Folic acid initiation rate was 99.26% for patients planning pregnancy. Initiation of vit B12 with folic acid was 28.33% in patients planning pregnancy. The rate of knowing that vitamin B12 deficiency causes NTD was 39.41% (family medicine specialists: 50%, general practitioners: 35.47%), and FMSs were statistically significant (p<0.05).Discussion: While the number of pregnant women who received folic acid only was sufficient, the number of pregnant women who took vitamin B12 with folic acid was very low. Family medicine specialists and general practitioners had insufficient knowledge that using vitamin B12 in combination with folic acid prevented NTD development. By preparing and implementing algorithms that can prevent NTDs, many life-long complications can be prevented.
目的:了解家庭保健中心医生对神经管缺损的病因及预防措施的了解程度。材料与方法:在本横断面研究中,406名全科医生和家庭医学专家进行了一项包括13个问题的调查。统计学方法采用卡方、Fisher精确检验和Pearson卡方分析。结果:共有406名医生(其中家庭医学专家110名,全科医生296名)参与了研究。81.53%的参与者在城市工作,18.47%的参与者在农村工作。妊娠前转介给全科医生的人数明显高于转介给家庭医学专家的人数。(p < 0.05)。36.95%的应答者在胚胎生命的第一个月就知道神经管已关闭。计划妊娠患者叶酸起始率为99.26%。在计划怀孕的患者中,开始服用叶酸的比例为28.33%。对维生素B12缺乏导致NTD知晓率为39.41%(家庭医学专家50%,全科医生35.47%),FMSs差异有统计学意义(p<0.05)。讨论:虽然只服用叶酸的孕妇数量是足够的,但服用维生素B12和叶酸的孕妇数量非常少。家庭医学专家和全科医生对将维生素B12与叶酸联合使用可预防NTD发展的认识不足。通过编制和实施可预防被忽视热带病的算法,可以预防许多终身并发症。
{"title":"Awareness of Neural Tube Defects in Family Physicians","authors":"Izzet Goker Kucuk, Utku Eser, Murat Çevik, K. Ongel","doi":"10.29333/JCEI/9707","DOIUrl":"https://doi.org/10.29333/JCEI/9707","url":null,"abstract":"Objective: The aim of this study was to measure the knowledge level of physicians working in family health centers about the conditions leading to neural tube defect (NTD) and preventive measures.\u0000Material and Methods: In this cross-sectional study, 406 general practitioners and family medicine specialists made a survey consisted of 13 questions. Chi-square, Fisher’s Exact test and Pearson chi-square analysis were applied as statistical methods.\u0000Results: A total of 406 physicians (family medicine specialists: 110, general practitioners: 296) participated in the study. 81.53% of the participants were working in a city and 18.47% were working in the countryside. The number of referral to general practitioners before pregnancy was significantly higher than that of family medicine specialists. (p<0.05). 36.95% of the respondents knew that the neural tube was closed in the first month of embryological life. Folic acid initiation rate was 99.26% for patients planning pregnancy. Initiation of vit B12 with folic acid was 28.33% in patients planning pregnancy. The rate of knowing that vitamin B12 deficiency causes NTD was 39.41% (family medicine specialists: 50%, general practitioners: 35.47%), and FMSs were statistically significant (p<0.05).\u0000Discussion: While the number of pregnant women who received folic acid only was sufficient, the number of pregnant women who took vitamin B12 with folic acid was very low. Family medicine specialists and general practitioners had insufficient knowledge that using vitamin B12 in combination with folic acid prevented NTD development. By preparing and implementing algorithms that can prevent NTDs, many life-long complications can be prevented.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45421892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transmission of COVID-19 Virus in the Presence of Neurologic Manifestations 有神经系统表现的COVID-19病毒传播
Pub Date : 2021-01-29 DOI: 10.31487/J.CEI.2020.03.06
M. Karimian, H. Famitafreshi
COVID-19 is a viral disease with a different set of manifestations. However, all clinical manifestations arenot occurring at the same time and some patients present the disease with an isolated or even without anyspecific symptoms. This disease besides neurologic symptoms in rare cases even presents itself with othersymptoms such as cardiac failure. In this case, a health care provider may not aware of this situation. Inthese situations, the transmission of the virus to individuals remains and people may not be aware of thehigh-risk situation. It is suggested to be aware of different clinical manifestations of COVID-19 disease andpreventive strategies keep for all patients.
COVID-19是一种具有一系列不同表现的病毒性疾病。然而,所有的临床表现并不是同时发生的,有些患者表现出孤立的症状,甚至没有任何特定的症状。这种疾病除了神经系统症状外,在极少数情况下甚至会出现其他症状,如心力衰竭。在这种情况下,医疗保健提供者可能不知道这种情况。在这些情况下,病毒在个人之间的传播仍然存在,人们可能没有意识到这种高风险情况。建议了解新冠肺炎的不同临床表现,并对所有患者采取相应的预防措施。
{"title":"Transmission of COVID-19 Virus in the Presence of Neurologic Manifestations","authors":"M. Karimian, H. Famitafreshi","doi":"10.31487/J.CEI.2020.03.06","DOIUrl":"https://doi.org/10.31487/J.CEI.2020.03.06","url":null,"abstract":"COVID-19 is a viral disease with a different set of manifestations. However, all clinical manifestations are\u0000not occurring at the same time and some patients present the disease with an isolated or even without any\u0000specific symptoms. This disease besides neurologic symptoms in rare cases even presents itself with other\u0000symptoms such as cardiac failure. In this case, a health care provider may not aware of this situation. In\u0000these situations, the transmission of the virus to individuals remains and people may not be aware of the\u0000high-risk situation. It is suggested to be aware of different clinical manifestations of COVID-19 disease and\u0000preventive strategies keep for all patients.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73248943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Evaluation of Risk Factors in Cases of Perinatal Asphyxia 围产期窒息危险因素的评价
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9563
Huseyin Gumus, Abit Demir
Aim: To determine the demographic characteristics of cases followed up with a diagnosis of perinatal asphyxia and to examine the risk factors in these cases.Material and Method: This retrospective study included 81 cases diagnosed with perinatal asphyxia and applied with hypothermia therapy in the neonatal intensive care unit of a tertiary level hospital between June 2018 and January 2020. The demographic characteristics of the cases and data related to perinatal risk factors were collected from the patient files and were analyzed using SPSS software.Results: When the pregnancy follow-up of the mothers was examined, 43.2% had attended antenatal examinations and 56.8% had not had regular follow-up. Delivery was by caesarean section in 24 (29.6%) cases and the normal spontaneous vaginal route in 57 (70.4%) cases. Risk factors determined before the birth were fetal bradycardia in 10 (10.1%) cases, pre-eclampsia in 5 (5.1%) cases, and gestational diabetes mellitus in 7 (7.1%) cases. Birth complications were recorded as prolonged difficult labour in 42 (42.4%) cases, cord prolapse in 7 (7.1%), abruptio placentae in 6 (6.1%) and amniotic fluid with meconium in 7 (7.1%) cases. No risk factors for perinatal asphyxia were determined in 4 (4.0%) cases.Conclusion: Perinatal asphyxia was observed at a higher rate in male gender infants and perinatal asphyxia was determined to develop more often in the infants of mothers who had not had antenatal follow-up. Of the known risk factors in the antenatal period and during the birth, difficult labour was observed at the highest rate.
目的:确定诊断为围产期窒息的病例的人口统计学特征,并检查这些病例的危险因素。材料和方法:本回顾性研究纳入了2018年6月至2020年1月在一家三级医院新生儿重症监护室诊断为围产期窒息并应用低温治疗的81例患者。从患者档案中收集病例的人口学特征和围产期危险因素相关数据,并使用SPSS软件进行分析。结果:当对母亲的妊娠随访进行检查时,43.2%的母亲参加了产前检查,56.8%的母亲没有定期随访。剖宫产24例(29.6%),自然阴道分娩57例(70.4%)。出生前确定的危险因素是10例(10.1%)胎儿心动过缓,5例(5.1%)先兆子痫,7例(7.1%)妊娠期糖尿病。42例(42.4%)发生分娩并发症,7例(7.1%)发生脐带脱垂,6例(6.1%)发生胎盘早剥,7例发生羊水胎粪。4例(4.0%)未确定围产期窒息的危险因素。结论:在男性婴儿中观察到围产期窒息的发生率较高,而在未进行产前随访的母亲的婴儿中,围产期窒息发生率更高。在产前和分娩期间的已知风险因素中,难产率最高。
{"title":"An Evaluation of Risk Factors in Cases of Perinatal Asphyxia","authors":"Huseyin Gumus, Abit Demir","doi":"10.29333/JCEI/9563","DOIUrl":"https://doi.org/10.29333/JCEI/9563","url":null,"abstract":"Aim: To determine the demographic characteristics of cases followed up with a diagnosis of perinatal asphyxia and to examine the risk factors in these cases.\u0000Material and Method: This retrospective study included 81 cases diagnosed with perinatal asphyxia and applied with hypothermia therapy in the neonatal intensive care unit of a tertiary level hospital between June 2018 and January 2020. The demographic characteristics of the cases and data related to perinatal risk factors were collected from the patient files and were analyzed using SPSS software.\u0000Results: When the pregnancy follow-up of the mothers was examined, 43.2% had attended antenatal examinations and 56.8% had not had regular follow-up. Delivery was by caesarean section in 24 (29.6%) cases and the normal spontaneous vaginal route in 57 (70.4%) cases. Risk factors determined before the birth were fetal bradycardia in 10 (10.1%) cases, pre-eclampsia in 5 (5.1%) cases, and gestational diabetes mellitus in 7 (7.1%) cases. Birth complications were recorded as prolonged difficult labour in 42 (42.4%) cases, cord prolapse in 7 (7.1%), abruptio placentae in 6 (6.1%) and amniotic fluid with meconium in 7 (7.1%) cases. No risk factors for perinatal asphyxia were determined in 4 (4.0%) cases.\u0000Conclusion: Perinatal asphyxia was observed at a higher rate in male gender infants and perinatal asphyxia was determined to develop more often in the infants of mothers who had not had antenatal follow-up. Of the known risk factors in the antenatal period and during the birth, difficult labour was observed at the highest rate.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41704585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of Biochemical Data in Pregnant Women Diagnosed with Restless Legs Syndrome 诊断为下肢不安综合征孕妇的生化指标调查
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9568
H. Savaş, M. Cimsir
Objective: Restless legs syndrome is a disorder that negatively affects quality of life. Pregnancy increases the frequency of restless leg syndrome. Symptoms that occur during pregnancy can become permanent. This study aimed to investigate the possible relationship between restless legs syndrome and biochemical parameters.Method: Alanya Alaaddin Keykubat University Education and Research Hospital was included in our randomly selected 100 pregnant women that applied to the Gynecology and Obstetrics outpatient clinic. The demographic characteristics and laboratory results of the patients were recorded. Patients were divided into two groups: one group with restless leg syndrome, and one group without. It was investigated whether there is a statistically significant difference between the demographic characteristics, blood biochemical levels, and hormonal levels between the two groups.Results: Age, height, weight, body mass index, ferritin with pregnancy week, magnesium, vitamin D, vitamin B12, thyroid stimulant hormone (TSH), hemoglobin, calcium, and aspartate aminotransferase / alanine aminotransferase (AST/ALT) levels were similar between the two groups (p>0.05).Conclusion: Restless legs syndrome is seen in about a third of the pregnancies. Pregnant patients do not come to the doctor with this complaint, because leg complaints are a normal condition caused by pregnancy. For this reason, they continue to live with symptoms of restless leg syndrome and endure this problem. However, this disease can be diagnosed with specific inquiries of physicians regarding restless leg syndrome. Although this study could establish no significant relationship between routine biochemical parameters and RLS, it is essential to examine the possible relationship in larger patient groups in terms of evidence-based medicine.
目的:不宁腿综合征是一种影响生活质量的疾病。怀孕会增加不宁腿综合症的发生频率。怀孕期间出现的症状可能是永久性的。本研究旨在探讨不宁腿综合征与生化指标之间的可能关系。方法:随机选择100例申请妇产科门诊的孕妇,纳入阿拉尼亚-阿拉丁-凯库巴特大学教育与研究医院。记录患者的人口学特征和实验室结果。患者分为两组:一组有不宁腿综合征,一组没有。调查两组患者的人口学特征、血液生化水平、激素水平是否存在统计学上的显著差异。结果:两组患者年龄、身高、体重、体质量指数、随孕周铁蛋白、镁、维生素D、维生素B12、甲状腺刺激素(TSH)、血红蛋白、钙、天冬氨酸转氨酶/丙氨酸转氨酶(AST/ALT)水平比较,差异无统计学意义(p < 0.05)。结论:不宁腿综合征见于约三分之一的孕妇。怀孕的病人不要带着这种抱怨来找医生,因为腿部抱怨是怀孕引起的正常情况。由于这个原因,他们继续生活在不宁腿综合症的症状中,忍受着这个问题。然而,这种疾病可以通过医生关于不宁腿综合征的具体询问来诊断。虽然本研究不能确定常规生化参数与RLS之间的显著关系,但从循证医学的角度来研究在更大的患者群体中可能存在的关系是必要的。
{"title":"Investigation of Biochemical Data in Pregnant Women Diagnosed with Restless Legs Syndrome","authors":"H. Savaş, M. Cimsir","doi":"10.29333/JCEI/9568","DOIUrl":"https://doi.org/10.29333/JCEI/9568","url":null,"abstract":"Objective: Restless legs syndrome is a disorder that negatively affects quality of life. Pregnancy increases the frequency of restless leg syndrome. Symptoms that occur during pregnancy can become permanent. This study aimed to investigate the possible relationship between restless legs syndrome and biochemical parameters.\u0000Method: Alanya Alaaddin Keykubat University Education and Research Hospital was included in our randomly selected 100 pregnant women that applied to the Gynecology and Obstetrics outpatient clinic. The demographic characteristics and laboratory results of the patients were recorded. Patients were divided into two groups: one group with restless leg syndrome, and one group without. It was investigated whether there is a statistically significant difference between the demographic characteristics, blood biochemical levels, and hormonal levels between the two groups.\u0000Results: Age, height, weight, body mass index, ferritin with pregnancy week, magnesium, vitamin D, vitamin B12, thyroid stimulant hormone (TSH), hemoglobin, calcium, and aspartate aminotransferase / alanine aminotransferase (AST/ALT) levels were similar between the two groups (p>0.05).\u0000Conclusion: Restless legs syndrome is seen in about a third of the pregnancies. Pregnant patients do not come to the doctor with this complaint, because leg complaints are a normal condition caused by pregnancy. For this reason, they continue to live with symptoms of restless leg syndrome and endure this problem. However, this disease can be diagnosed with specific inquiries of physicians regarding restless leg syndrome. Although this study could establish no significant relationship between routine biochemical parameters and RLS, it is essential to examine the possible relationship in larger patient groups in terms of evidence-based medicine.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48362040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Treatment of the Ascending Aorta Aneurysm in a Patient with Horse Shoe Kidney 马蹄形肾患者升主动脉动脉瘤的治疗
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9561
S. B. Deşer
The Horse Shoe Kidney (HSK) is one of the most common congenital malformation of lower poles fusion of kidneys. Despite, HSK is relatively seen with a high incidence of 0.15-0.33%, accompanying with Ascending Aorta Aneurysm is rarely seen. Here, we present the first case to our knowledge that accompanying Ascending Aorta Aneurysm to Horse Shoe Kidney.
马蹄肾(HSK)是最常见的先天性肾下极融合畸形之一。尽管HSK发病率较高,为0.15-0.33%,但合并升主动脉动脉瘤少见。在这里,我们报告了据我们所知的第一例伴随升主动脉动脉瘤到马蹄肾的病例。
{"title":"Treatment of the Ascending Aorta Aneurysm in a Patient with Horse Shoe Kidney","authors":"S. B. Deşer","doi":"10.29333/JCEI/9561","DOIUrl":"https://doi.org/10.29333/JCEI/9561","url":null,"abstract":"The Horse Shoe Kidney (HSK) is one of the most common congenital malformation of lower poles fusion of kidneys. Despite, HSK is relatively seen with a high incidence of 0.15-0.33%, accompanying with Ascending Aorta Aneurysm is rarely seen. Here, we present the first case to our knowledge that accompanying Ascending Aorta Aneurysm to Horse Shoe Kidney.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45615658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Patients with Asthma and Asthma Control: A Retrospective Analysis of Reported Data from Primary Healthcare Centers in Agadir city, Morocco (2013 - 2019) 哮喘患者的特征和哮喘控制:摩洛哥阿加迪尔市初级保健中心报告数据的回顾性分析(2013-2019)
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9566
Youssef Bouchriti, Oumaima Elghazali, A. Kharbach, H. Gougueni, M. Haddou, A. Achbani
The study aims to describe the profile of asthma patients in Agadir city (Morocco) during a period of 7 years (2013 to 2019) to identify the factors associated with asthma control. Practically, a retrospective analysis was conducted on data collected from 6 primary healthcare centers (PHC) in the city. The reported data are the age, gender, location, date of first consultation, dates of consultations, and treatment of 701 patients and care centers (PHC). Also, the proportional odds model for ordinal logistic regression was used to determine the most variables can be associated with asthma control. The analysis reveals a spatial and temporal variation according to gender. The average age of patients is 43 years. The two-thirds of all recorded cases were reported in 2018 and 2019. Furthermore, the proportion of female and male represents 63% and 37% of the total reported cases, respectively. Generally, the female proportion is higher than male for all age groups. Moreover, the analysis reveals that the asthma control was reported for 19% of cases while the rest was uncontrolled. This control seems be more observed for males (OR: 1.28; 95% CI [0.87; 1.87]), for patients with age between 29 and 44 years (OR: 2.3; 95% CI [1.54; 3.44], p < 0. 001), and for patients who were cared for at the PHC1 center (OR: 21.06; 95% CI [11.13; 39.85], p < 0.001) and at the PHC2 center (OR: 13.19; 95% CI [6.54; 29.54], p < 0.001). Eventually, the current study emphasizes that the gender and care centers are the most associated factors of asthma control.
该研究旨在描述阿加迪尔市(摩洛哥)7年(2013年至2019年)哮喘患者的情况,以确定与哮喘控制相关的因素。实际上,对从该市6个初级保健中心(PHC)收集的数据进行了回顾性分析。报告的数据是701名患者和护理中心(PHC)的年龄、性别、地点、首次会诊日期、会诊日期和治疗情况。此外,使用有序逻辑回归的比例优势模型来确定与哮喘控制相关的大多数变量。该分析揭示了性别在空间和时间上的差异。患者的平均年龄为43岁。所有记录在案的病例中有三分之二是在2018年和2019年报告的。此外,女性和男性的比例分别占报告病例总数的63%和37%。一般来说,在所有年龄组中,女性的比例都高于男性。此外,分析显示,19%的病例哮喘得到了控制,而其余病例则没有得到控制。这种对照似乎在男性(OR:1.28;95%CI[0.87;1.87])和年龄在29至44岁之间的患者中更为明显(OR:2.3;95%CI[1.54;3.44],p<0.01)。001),以及在PHC1中心接受护理的患者(OR:21.06;95%CI[11.13;39.85],p<0.001)和在PHC2中心接受护理(OR:13.19;95%CI[6.54;29.54],p<0.001)。最终,当前的研究强调,性别和护理中心是哮喘控制的最相关因素。
{"title":"Characteristics of Patients with Asthma and Asthma Control: A Retrospective Analysis of Reported Data from Primary Healthcare Centers in Agadir city, Morocco (2013 - 2019)","authors":"Youssef Bouchriti, Oumaima Elghazali, A. Kharbach, H. Gougueni, M. Haddou, A. Achbani","doi":"10.29333/JCEI/9566","DOIUrl":"https://doi.org/10.29333/JCEI/9566","url":null,"abstract":"The study aims to describe the profile of asthma patients in Agadir city (Morocco) during a period of 7 years (2013 to 2019) to identify the factors associated with asthma control. Practically, a retrospective analysis was conducted on data collected from 6 primary healthcare centers (PHC) in the city. The reported data are the age, gender, location, date of first consultation, dates of consultations, and treatment of 701 patients and care centers (PHC). Also, the proportional odds model for ordinal logistic regression was used to determine the most variables can be associated with asthma control. The analysis reveals a spatial and temporal variation according to gender. The average age of patients is 43 years. The two-thirds of all recorded cases were reported in 2018 and 2019. Furthermore, the proportion of female and male represents 63% and 37% of the total reported cases, respectively. Generally, the female proportion is higher than male for all age groups. Moreover, the analysis reveals that the asthma control was reported for 19% of cases while the rest was uncontrolled. This control seems be more observed for males (OR: 1.28; 95% CI [0.87; 1.87]), for patients with age between 29 and 44 years (OR: 2.3; 95% CI [1.54; 3.44], p < 0. 001), and for patients who were cared for at the PHC1 center (OR: 21.06; 95% CI [11.13; 39.85], p < 0.001) and at the PHC2 center (OR: 13.19; 95% CI [6.54; 29.54], p < 0.001). Eventually, the current study emphasizes that the gender and care centers are the most associated factors of asthma control.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47782654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of Estimated and Real COVID-19 Cases and Deaths for 45 Days 45天内COVID-19估计病例和实际死亡病例的比较
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9565
M. Sozen, H. Savaş, Zafer Cakir
The Coronavirus Disease 2019 (COVID-19) is caused by the new type of coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), emerged in China at the end of 2019, and spread all over the world in a very short time The World Health Organization (WHO) declared COVID-19 a global pandemic due to its rapid spread and lack of effective vaccination, immunization and treatment In this study, we aimed to make a retrospective evaluation of forty-five days of COVID-19 cases and deaths simulated by the modified mathematical model which was previously established and published by us 30 days and 45 days of COVID-19 cases and deaths which were estimated by our modified mathematical model were compared to the real cases and deaths in Turkey since 15 03 2020 The COVID-19 cases increased to a significant level on 20 03 2020 in Turkey The modified mathematical modeling results' estimation accuracy remained above 90% until 13 04 2020 This rate was 78 40% on 28 04 2020 The modified mathematical modeling estimation for the COVID-19 deaths started on 20 03 2020 because the number of deaths were then significant enough for estimation with the modified mathematical model The estimation accuracy for the number of deaths was 100% with a value of 37 on 23 March 2020, and after that, it had always remained above 90% until 13 04 2020 Finally, it was 66 08% on 28 04 2020 The estimation accuracies of the modified mathematical model about the COVID-19 cases in Turkey for 30 days and 45 days were above 90% and 78% respectively The estimation accuracies of the modified mathematical model about the COVID- 19 deaths in Turkey for the 30-day and 45-day periods were above 90% and 66%, respectively This result suggests that the modified mathematical model is available for estimating the course of disease outbreaks and pandemics The model should be developed through future studies, which will improve its estimation accuracy [ABSTRACT FROM AUTHOR] Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
2019冠状病毒病(新冠肺炎)是由2019年底在中国出现的新型冠状病毒严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的,并在很短的时间内传播到世界各地。世界卫生组织(世界卫生组织)宣布新冠肺炎为全球大流行,免疫和治疗在本研究中,我们的目的是对45天的新冠肺炎病例和死亡进行回顾性评估,该模型由我们之前建立和发布的修正数学模型模拟。30天和45天的新冠肺炎病例和死亡(由我们修正的数学模型估计)与土耳其自2020年3月15日以来的真实病例和死亡相比较土耳其2020年3月20日的显著水平修正后的数学模型结果的估计准确率在2020年4月13日之前保持在90%以上该比率在2020年04月28日为78.40%新冠肺炎死亡人数的修正后数学模型估计始于2020年03月20日,因为当时死亡人数足够显著,可以使用修正后的模型进行估计死亡人数的准确率为100%,2020年3月23日为37,此后,直到2020年4月13日,死亡人数一直保持在90%以上。最后,2020年4月28日为66.08%土耳其新冠肺炎病例30天和45天修正数学模型的估计准确率分别高于90%和78%土耳其新冠肺炎-19死亡病例30天的估计准确度高于90%和66%,这一结果表明,改进的数学模型可用于估计疾病暴发和流行病的过程。该模型应通过未来的研究来开发,这将提高其估计准确性[作者摘要]《临床与实验研究杂志》版权归Modestum Publications所有,未经版权持有人明确书面许可,不得将其内容复制或通过电子邮件发送到多个网站或发布到listserv,或个人使用的电子邮件文章本摘要可能会被删节,对副本的准确性不作任何保证用户应参考材料的原始出版版本以获取完整摘要(版权适用于所有摘要)
{"title":"Comparison of Estimated and Real COVID-19 Cases and Deaths for 45 Days","authors":"M. Sozen, H. Savaş, Zafer Cakir","doi":"10.29333/JCEI/9565","DOIUrl":"https://doi.org/10.29333/JCEI/9565","url":null,"abstract":"The Coronavirus Disease 2019 (COVID-19) is caused by the new type of coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), emerged in China at the end of 2019, and spread all over the world in a very short time The World Health Organization (WHO) declared COVID-19 a global pandemic due to its rapid spread and lack of effective vaccination, immunization and treatment In this study, we aimed to make a retrospective evaluation of forty-five days of COVID-19 cases and deaths simulated by the modified mathematical model which was previously established and published by us 30 days and 45 days of COVID-19 cases and deaths which were estimated by our modified mathematical model were compared to the real cases and deaths in Turkey since 15 03 2020 The COVID-19 cases increased to a significant level on 20 03 2020 in Turkey The modified mathematical modeling results' estimation accuracy remained above 90% until 13 04 2020 This rate was 78 40% on 28 04 2020 The modified mathematical modeling estimation for the COVID-19 deaths started on 20 03 2020 because the number of deaths were then significant enough for estimation with the modified mathematical model The estimation accuracy for the number of deaths was 100% with a value of 37 on 23 March 2020, and after that, it had always remained above 90% until 13 04 2020 Finally, it was 66 08% on 28 04 2020 The estimation accuracies of the modified mathematical model about the COVID-19 cases in Turkey for 30 days and 45 days were above 90% and 78% respectively The estimation accuracies of the modified mathematical model about the COVID- 19 deaths in Turkey for the 30-day and 45-day periods were above 90% and 66%, respectively This result suggests that the modified mathematical model is available for estimating the course of disease outbreaks and pandemics The model should be developed through future studies, which will improve its estimation accuracy [ABSTRACT FROM AUTHOR] Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46928629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Visual Impairment among School Going Paediatric Group Children in Rural Areas of Bihar and Jharkhand: A Population Based Study 比哈尔邦和贾坎德邦农村地区学龄儿童视力障碍的人群研究
Pub Date : 2021-01-16 DOI: 10.29333/JCEI/9564
C. Pandey, S. Kumari, Vivek Kumar
Objective: The study aims to ascertain the prevalence and cause of low vision/ blindness in children of the rural population of the Indian states of Bihar and Jharkhand and justify the investment done on a population based survey for the particular age group.Material and Methods: The documentation of 1500 children was done with respect to their demographic data and ophthalmological examination.Results: The prevalence of childhood blindness was observed to be 0.2% with a predilection to female sex. The most common cause of visual impairment was uncorrected refractive error with incidences of blindness caused due to correctable condition of congenital cataract.Conclusion: Keeping in view of the life expectancy of 68 years in India, it can be reasonably stated that the number of years of visual impairment that can be shunned by these children oriented population based programs will have a significant impact on the burden being posed.
目的:本研究旨在确定印度比哈尔邦和贾坎德邦农村人口中儿童低视力/失明的患病率和原因,并证明为特定年龄组进行基于人口的调查所做的投资是合理的。材料和方法:对1500名儿童的人口统计数据和眼科检查进行了记录。结果:儿童期失明的患病率为0.2%,且偏爱女性。视力受损最常见的原因是未矫正的屈光不正,先天性白内障的可矫正条件导致失明的发生率。结论:考虑到印度68岁的预期寿命,可以合理地说,这些以儿童为导向的人口计划可以避免的视力障碍年数将对造成的负担产生重大影响。
{"title":"Visual Impairment among School Going Paediatric Group Children in Rural Areas of Bihar and Jharkhand: A Population Based Study","authors":"C. Pandey, S. Kumari, Vivek Kumar","doi":"10.29333/JCEI/9564","DOIUrl":"https://doi.org/10.29333/JCEI/9564","url":null,"abstract":"Objective: The study aims to ascertain the prevalence and cause of low vision/ blindness in children of the rural population of the Indian states of Bihar and Jharkhand and justify the investment done on a population based survey for the particular age group.\u0000Material and Methods: The documentation of 1500 children was done with respect to their demographic data and ophthalmological examination.\u0000Results: The prevalence of childhood blindness was observed to be 0.2% with a predilection to female sex. The most common cause of visual impairment was uncorrected refractive error with incidences of blindness caused due to correctable condition of congenital cataract.\u0000Conclusion: Keeping in view of the life expectancy of 68 years in India, it can be reasonably stated that the number of years of visual impairment that can be shunned by these children oriented population based programs will have a significant impact on the burden being posed.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43124189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Trial Ethics in the Era of COVID-19 Pandemic 新冠肺炎大流行时代的临床试验伦理
Pub Date : 2020-11-28 DOI: 10.29333/jcei/9286
Muhammet Arslan, Nüket Örnek Büken
The world has been suffering from the deadly effects of coronavirus and seemingly will continue to suffer for quite more time. Humanity has witnessed many kinds of outbreaks that have affected the population endemically or epidemically. Urgent need for treatment of COVID-19 is necessary and essential. In this article the cornerstones of clinical trial ethics, current publications and statements are analyzed to overcome the difficulties of pandemics with an additional focus on Turkey.The researching physician, volunteering patients, industry, institutions, and national/international ethico-legal bodies are playing important role in clinical research. As stated in the Hippocratic Oath, it is a physician’s duty to “first do no harm”. Many international documents also state the fact that preserving the dignity of people and basic rights is the most essential attitude.Clinical trials follow a certain set of principles regulated by legislative bodies. Medical ethics try to establish a common base for all research to fulfill the need for an internationally acceptable standard. Rather than serving the benefit of qualifications, ethical standards preserve qualitative values. It can be said that medical ethics is an appropriate discipline to serve the improvement of both science and morals.
世界一直在遭受冠状病毒的致命影响,而且似乎还将持续相当长的时间。人类目睹了多种疾病的爆发,这些疾病地方性地或流行病地影响了人口。迫切需要治疗COVID-19是必要和必不可少的。本文分析了临床试验伦理的基础、目前的出版物和声明,以克服流行病的困难,并进一步关注土耳其。研究医师、志愿患者、行业、机构和国家/国际伦理法律团体在临床研究中发挥着重要作用。正如希波克拉底誓言中所述,医生的职责是“首先不造成伤害”。许多国际文件也指出,维护人的尊严和基本权利是最基本的态度。临床试验遵循立法机构规定的一套原则。医学伦理学试图为所有研究建立一个共同的基础,以满足国际上可接受的标准的需要。道德标准不是服务于资格的利益,而是维护质量价值。可以说,医学伦理学是一门为科学和道德发展服务的学科。
{"title":"Clinical Trial Ethics in the Era of COVID-19 Pandemic","authors":"Muhammet Arslan, Nüket Örnek Büken","doi":"10.29333/jcei/9286","DOIUrl":"https://doi.org/10.29333/jcei/9286","url":null,"abstract":"The world has been suffering from the deadly effects of coronavirus and seemingly will continue to suffer for quite more time. Humanity has witnessed many kinds of outbreaks that have affected the population endemically or epidemically. Urgent need for treatment of COVID-19 is necessary and essential. In this article the cornerstones of clinical trial ethics, current publications and statements are analyzed to overcome the difficulties of pandemics with an additional focus on Turkey.\u0000The researching physician, volunteering patients, industry, institutions, and national/international ethico-legal bodies are playing important role in clinical research. As stated in the Hippocratic Oath, it is a physician’s duty to “first do no harm”. Many international documents also state the fact that preserving the dignity of people and basic rights is the most essential attitude.\u0000Clinical trials follow a certain set of principles regulated by legislative bodies. Medical ethics try to establish a common base for all research to fulfill the need for an internationally acceptable standard. Rather than serving the benefit of qualifications, ethical standards preserve qualitative values. It can be said that medical ethics is an appropriate discipline to serve the improvement of both science and morals.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46112124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
COVID-19 and End-stage Kidney Disease in Morocco: Staying Safe during Dialysis 摩洛哥的COVID-19和终末期肾病:透析期间的安全
Pub Date : 2020-11-28 DOI: 10.29333/jcei/9280
A. Naciri, A. Achbani, M. A. Baba, Youssef Bouchriti, H. Sine, A. Kharbach
Since World Health Organization (WHO) declared a global Health Emergency at the end of January 2020 caused by the novel coronavirus 2019-nCoV, the rapid spread of this pandemic poses unprecedented challenges throughout the world.Hemodialysis patients are more susceptible to SARS-CoV-2 pneumonia than the general population. Dialysis physicians, health workers should have clinical knowledge of epidemic COVID-19, epidemic prevention tools, and required guidelines.This paper aims to focus on the Moroccan society of nephrology recommendations and the Ministry of Health guidelines to protect both healthcare workers and hemodialysis patients from the virus.A package of measures has been recommended by the Ministry of Health to ensure continuity of health services for hemodialysis patients with Covid-19. Besides, the Moroccan society of nephrology recommendations has been adopted to ensure quality care for this vulnerable category throughout the epidemic.
自世界卫生组织(世界卫生组织)于2020年1月底宣布由新型冠状病毒2019-nCoV引起的全球卫生紧急状态以来,这一流行病的迅速传播在世界各地带来了前所未有的挑战。血液透析患者比普通人群更容易感染严重急性呼吸系统综合征冠状病毒2型肺炎。透析医生、卫生工作者应具备新冠肺炎疫情的临床知识、防疫工具和所需指南。本文旨在关注摩洛哥肾脏病学会的建议和卫生部的指导方针,以保护医护人员和血液透析患者免受病毒感染。卫生部建议采取一系列措施,以确保新冠肺炎血液透析患者的卫生服务的连续性。此外,摩洛哥肾脏病学会的建议已被采纳,以确保在整个疫情期间为这一弱势群体提供高质量的护理。
{"title":"COVID-19 and End-stage Kidney Disease in Morocco: Staying Safe during Dialysis","authors":"A. Naciri, A. Achbani, M. A. Baba, Youssef Bouchriti, H. Sine, A. Kharbach","doi":"10.29333/jcei/9280","DOIUrl":"https://doi.org/10.29333/jcei/9280","url":null,"abstract":"Since World Health Organization (WHO) declared a global Health Emergency at the end of January 2020 caused by the novel coronavirus 2019-nCoV, the rapid spread of this pandemic poses unprecedented challenges throughout the world.\u0000Hemodialysis patients are more susceptible to SARS-CoV-2 pneumonia than the general population. Dialysis physicians, health workers should have clinical knowledge of epidemic COVID-19, epidemic prevention tools, and required guidelines.\u0000This paper aims to focus on the Moroccan society of nephrology recommendations and the Ministry of Health guidelines to protect both healthcare workers and hemodialysis patients from the virus.\u0000A package of measures has been recommended by the Ministry of Health to ensure continuity of health services for hemodialysis patients with Covid-19. Besides, the Moroccan society of nephrology recommendations has been adopted to ensure quality care for this vulnerable category throughout the epidemic.","PeriodicalId":53255,"journal":{"name":"Journal of Clinical and Experimental Investigations","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49150890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Journal of Clinical and Experimental Investigations
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1