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A study on factors influencing the intrinsic capacity of elderly people in rural areas based on the random forest model. 基于随机森林模型的农村老年人内在能力影响因素研究
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-10 DOI: 10.1080/13548506.2025.2591010
Hong Su, Dongwei Liu, Liying Zhang, Yuqiu Zhou, Haina Wang, Qi Li

Enhancing and maintaining the intrinsic capacity of the elderly is crucial for preventing and mitigating disability and promoting healthy aging. This study explore the current status of intrinsic capacity among elderly individuals in rural areas and analyze the influencing factors. This study included 592 participants who were ≥60 years in rural areas of China. Investigations were conducted using a general information questionnaire, the UCLA Loneliness Scale, the Perceived Stress Scale, the abbreviated version of the Lubben Social Network Scale, the Family Caregiving Index Scale, the Health-Promoting Lifestyle Scale, the ICOPE intrinsic capacity screening tool, and a grip strength dynamometer. We used correlations, regressions, and random forest model for the analyses. The random forest algorithm results indicate that the minimum error occurred when the lambda (λ) value was set at 0.8978, corresponding to nine influencing factors. The results of multiple stepwise regression analysis indicate that health-promoting lifestyle, family functioning, sense of loneliness, perceived stress, grip strength, social network, number of chronic diseases, educational level, and economic income are the main factors affecting intrinsic capacity (p < 0.05) among rural elderly individuals. Health service personnel can identify high-risk groups early and implement effective interventions based on the factors influencing the intrinsic capacity of rural elderly individuals.

增强和保持老年人的内在能力,对于预防和减轻残疾,促进健康老龄化至关重要。本研究旨在探讨农村老年人内在能力的现状,并分析其影响因素。本研究纳入592名年龄≥60岁的中国农村参与者。采用一般信息问卷、UCLA孤独量表、感知压力量表、简略版Lubben社会网络量表、家庭照顾指数量表、健康促进生活方式量表、ICOPE内在能力筛选工具和握力测力仪进行调查。我们使用相关性、回归和随机森林模型进行分析。随机森林算法结果表明,λ值为0.8978时误差最小,对应9个影响因素。多元逐步回归分析结果表明,促进健康的生活方式、家庭功能、孤独感、压力感知、握力、社会网络、慢性疾病数量、教育程度和经济收入是影响内在能力的主要因素(p
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引用次数: 0
Maternal obesity and healthcare experiences: perceptions and challenges in prenatal and postpartum care. 产妇肥胖和保健经验:产前和产后护理的认识和挑战。
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-08 DOI: 10.1080/13548506.2025.2611360
Elizete Sampaio Araujo, Claudia Galindo Novoa, Lorenza Machado Teixeira, Patrícia Medici Dualib, Edward Araujo Júnior, Gustavo Yano Callado, Evelyn Traina, Victor Hugo Saucedo Sanchez, Rosiane Mattar

Prenatal care for women living with obesity constitutes a significant healthcare challenge, often compromised by inconsistent and adverse experiences. This research aimed to explore how pregnant and postpartum women with obesity in Brazil perceive the healthcare they receive. Through a qualitative field study employing netnographic methods and the 'Collective Subject Discourse' technique, we examined testimonies from 149 participants. Our findings reveal contrasting experiences: while 52.7% reported positive interactions, valuing respect and empathy, a substantial 47.3% encountered substandard care characterized by weight-based stigma and insufficient information. The research highlights inconsistencies in prenatal healthcare services and emphasizes the critical need to integrate anti-stigma approaches and humanized care practices.

对肥胖妇女的产前护理是一项重大的保健挑战,往往受到不一致和不利经历的影响。本研究旨在探讨巴西肥胖孕妇和产后妇女如何看待她们接受的医疗保健。通过采用网络学方法和“集体主体话语”技术的定性实地研究,我们检查了149名参与者的证词。我们的研究结果揭示了截然不同的经历:虽然52.7%的人报告了积极的互动,重视尊重和同理心,但47.3%的人遇到了以体重为基础的耻辱和信息不足为特征的不合格护理。该研究突出了产前保健服务的不一致性,并强调了整合反污名化方法和人性化护理实践的迫切需要。
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引用次数: 0
Evaluating working memory functioning in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review and meta-analysis. 评估肌痛性脑脊髓炎/慢性疲劳综合征患者的工作记忆功能:系统回顾和荟萃分析
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-08 DOI: 10.1080/13548506.2025.2606183
Maddison Penson, Kate Kelly

Individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) frequently report pronounced cognitive difficulties, yet the empirical literature has not fully characterised how discrete components of working memory are affected. Given that working memory serves as a foundational system supporting complex cognitive processes, differentiating performance across verbal and visual modalities provides critical insight into which higher-order functions may be most vulnerable. This systematic review/meta-analysis aimed to synthesise current research to investigate how ME/CFS impacts working memory systems. Using PRISMA guidelines, a systematic search of 6 databases was undertaken (MEDLINE, CINAHL, Web of Science Core Collection, PubMed, EMBASE and PsycINFO). Initially, 10 574 papers were imported and following screening 34 studies of good to strong quality met the inclusion criteria. A series of random effects models were utilised to analyse working memory. Results indicated a significant difference and large effect size between ME/CFS individuals and controls on verbal working memory tasks; however, no significant difference in visual working memory performance was found between the groups. Following the breakdown of these subsystems into span/attentional control tasks and object/spatial tasks, these results remained consistent. These findings contribute to the body of ME/CFS research by articulating where specific working memory deficits lie. Specifically, they show that individuals with ME/CFS have impaired verbal memory performance. This knowledge can guide future research targeting higher-order verbal cognition and underscores the importance of recognising cognitive manifestations within ME/CFS clinical care.

患有肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)的个体经常报告明显的认知困难,然而经验文献并没有完全描述工作记忆的离散组成部分是如何受到影响的。鉴于工作记忆是支持复杂认知过程的基础系统,区分语言和视觉模式的表现为了解哪些高阶功能可能最脆弱提供了关键的见解。本系统综述/荟萃分析旨在综合当前研究,探讨ME/CFS如何影响工作记忆系统。采用PRISMA指南,系统检索了6个数据库(MEDLINE, CINAHL, Web of Science Core Collection, PubMed, EMBASE和PsycINFO)。最初,导入了10 574篇论文,经过筛选,34篇质量良好到高质量的研究符合纳入标准。采用一系列随机效应模型对工作记忆进行分析。结果表明,ME/CFS个体与对照组在言语工作记忆任务上存在显著差异,且效应量较大;然而,视觉工作记忆的表现在两组之间没有显著差异。在将这些子系统分解为跨度/注意力控制任务和对象/空间任务之后,这些结果保持一致。这些发现通过阐明具体的工作记忆缺陷在哪里,为ME/CFS研究的主体做出了贡献。具体来说,他们表明患有ME/CFS的人的言语记忆表现受损。这些知识可以指导未来针对高阶言语认知的研究,并强调在ME/CFS临床护理中识别认知表现的重要性。
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引用次数: 0
Development and interpretation prediction model for depressive symptoms in patients with chronic kidney disease: a cross-sectional study based on NHANES. 慢性肾病患者抑郁症状预测模型的建立与解释:基于NHANES的横断面研究
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-06 DOI: 10.1080/13548506.2025.2611359
Feng Cao, Enguang Li, Fangzhu Ai, Hongjuan Wen, Ping Tang, Botang Guo

Depressive symptoms are prevalent and impactful among patients with chronic kidney disease (CKD). However, traditional screening methods often yield high false positive and false negative rates in this population. This study aimed to develop a machine learning-based model to improve the early identification of depressive symptoms risk among CKD patients.Data were extracted from NHANES 2011-March 2020 (pre-pandemic) as the model development cohort and split into a training cohort and an internal validation cohort. A temporally independent NHANES cycle (August 2021-August 2023) was used as an external validation cohort. Predictors were selected using least absolute shrinkage and selection operator regression. Eight machine learning algorithms were trained. Given outcome imbalance, discrimination was primarily compared using recall, precision, and F1 score, with AUCs reported as secondary measures. Calibration was assessed using calibration curves and the Brier score, and clinical utility was evaluated using decision curve analysis. SHAP was used to interpret feature contributions in the selected model.In the internal validation cohort, the RF model achieved recall 0.826, precision 0.569, and F1 score 0.673, with an AUC of 0.941. In the external validation cohort, the RF model achieved recall 0.826, precision 0.136, and F1 score 0.234, with an AUC of 0.711. SHAP identified poverty-income ratio, smoking status, weight, and urine albumin-to-creatinine ratio as the top predictors, followed by marital status, education level, gender, BMI, albumin, and hypertension.This study provides a clinically actionable tool to stratify the risk of clinically significant depressive symptoms in patients with CKD, which may support targeted screening, timely mental health assessment or referral, and more efficient allocation of clinical resources. SHAP-based explanations help interpret individual risk estimates to inform patient-centered management.

抑郁症状在慢性肾脏疾病(CKD)患者中普遍存在且具有影响力。然而,传统的筛查方法往往产生高假阳性和假阴性率在这一人群。本研究旨在开发一种基于机器学习的模型,以提高CKD患者抑郁症状风险的早期识别。数据提取自NHANES 2011- 2020年3月(大流行前),作为模型开发队列,并分为培训队列和内部验证队列。采用暂时独立的NHANES周期(2021年8月- 2023年8月)作为外部验证队列。使用最小绝对收缩和选择算子回归选择预测因子。训练了八种机器学习算法。考虑到结果不平衡,主要使用召回率、精确度和F1评分来比较歧视,auc作为次要测量。采用校准曲线和Brier评分评估校准,采用决策曲线分析评估临床效用。使用SHAP来解释所选模型中的特征贡献。在内部验证队列中,RF模型的召回率为0.826,精度为0.569,F1得分为0.673,AUC为0.941。在外部验证队列中,RF模型的召回率为0.826,精度为0.136,F1得分为0.234,AUC为0.711。SHAP发现,贫困收入比、吸烟状况、体重和尿白蛋白与肌酐比是最重要的预测因素,其次是婚姻状况、教育水平、性别、BMI、白蛋白和高血压。本研究为CKD患者临床显著抑郁症状的风险分层提供了一种临床可操作的工具,这可能支持有针对性的筛查,及时的心理健康评估或转诊,以及更有效的临床资源分配。基于shap的解释有助于解释个体风险估计,从而为以患者为中心的管理提供信息。
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引用次数: 0
Artificial intelligence anxiety and AI general attitudes among future healthcare workers: a cross-sectional study. 未来医护人员的人工智能焦虑和人工智能总体态度:一项横断面研究
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-04 DOI: 10.1080/13548506.2025.2607660
Birgül Yabana Kiremit, İlayda Şener, Kerem Can Tabak

The growing presence of artificial intelligence (AI) in everyday life and business has led to increased anxiety among health sector employees. This study investigated the relationship between anxiety and attitudes toward AI among health sciences students at a university in northern Türkiye. We conducted a cross-sectional study involving final-year students, utilizing a socio-demographic questionnaire, the General Attitude Towards Artificial Intelligence Scale (GAAIS), and the Artificial Intelligence Anxiety Scale (AIAS). Data was analyzed using SPSS 29.0, with 415 students participating. Notably, 97.3% heard AI before, and 75.1% have knowledge about it. Male students exhibited a more positive attitude toward AI. Differences in AI anxiety and attitudes were observed across departments, with Orthotics and Prosthetics students showing the highest positive attitude score (45.79 ± 8.21), while nursing students reported the highest levels of AI anxiety. Variations in learning and job anxiety, which are sub-dimensions of AI anxiety, were found among faculty members. Nursing students experienced the most learning anxiety, while health management students faced the greatest job replacement anxiety. Our findings suggest that familiarity with AI is correlated with positive attitudes and lower anxiety levels. Increased positive attitudes were linked to reduced anxiety. Overall, this study indicates that knowledge of AI influences students' attitudes and anxiety levels, with learning- and job-related anxiety being particularly prominent. It is believed that incorporating AI into education and demonstrating its benefits in professional settings can help alleviate these negative feelings.

人工智能(AI)在日常生活和商业中的日益普及,导致卫生部门员工的焦虑情绪日益加剧。本研究调查了日本北部一所大学健康科学专业学生对人工智能的焦虑与态度之间的关系。我们利用社会人口调查问卷、对人工智能的一般态度量表(GAAIS)和人工智能焦虑量表(AIAS)对高年级学生进行了一项横断面研究。数据采用SPSS 29.0进行分析,共有415名学生参与。值得注意的是,97.3%的人听说过人工智能,75.1%的人对人工智能有所了解。男生对人工智能的态度更为积极。各院系对人工智能的焦虑和态度存在差异,其中矫形与修复专业学生的积极态度得分最高(45.79±8.21),护理专业学生的人工智能焦虑水平最高。作为人工智能焦虑的子维度,学习焦虑和工作焦虑在教师中也存在差异。护理专业学生的学习焦虑程度最高,健康管理专业学生的工作替代焦虑程度最高。我们的研究结果表明,熟悉人工智能与积极的态度和较低的焦虑水平相关。积极态度的增加与焦虑的减少有关。总体而言,本研究表明,人工智能知识影响学生的态度和焦虑水平,其中与学习和工作相关的焦虑尤为突出。人们认为,将人工智能纳入教育,并在专业环境中展示其好处,可以帮助缓解这些负面情绪。
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引用次数: 0
Appearance anxiety and social ostracism among maxillofacial trauma patients: role of perceived social support and post-traumatic growth. 颌面部创伤患者外表焦虑与社会排斥:感知社会支持与创伤后成长的关系。
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-04 DOI: 10.1080/13548506.2025.2606182
Aaisha Shaukat, Samina Rashid, Maaz Ahmed

The current study aims to identify the association between appearance anxiety, post-traumatic growth, perceived social support and social ostracism and the role of post-traumatic growth as a mediator and perceived social support as a moderator among maxillofacial trauma patients. A total number of 172 maxillofacial trauma patients (M = 76, F = 96) participated in this study. The data were compiled using the Appearance Anxiety Inventory, Ostracism Experience Scale, Multidimensional Scale of Perceived Social Support and the Post-Traumatic Growth Inventory. A cross-sectional design was used. Pearson correlations and PROCESS macro were employed to examine mediation and moderation effects, and independent samples t-tests assessed gender differences. The results revealed a negative association between appearance anxiety, post-traumatic growth and perceived social support. Additionally, there was a significant positive relationship between post-traumatic growth and perceived social support. Results showed that maxillofacial trauma patient's post-traumatic growth and perceived social support were negatively correlated with social ostracism. The study's findings suggest that post-traumatic growth mediates, and perceived social support moderates the relationship between appearance anxiety and social ostracism among maxillofacial trauma patients. This study will facilitate implications required for multifaceted approach and interventions to trauma recovery for the betterment of overall wellbeing of maxillofacial trauma patients.

本研究旨在探讨颌面部创伤患者外表焦虑、创伤后成长、感知社会支持和社会排斥之间的关系,以及创伤后成长的中介作用和感知社会支持的调节作用。共172例颌面部外伤患者(M = 76, F = 96)参与本研究。数据采用外表焦虑量表、排斥体验量表、多维感知社会支持量表和创伤后成长量表编制。采用横断面设计。采用Pearson相关和PROCESS宏观检验中介和调节效应,独立样本t检验评估性别差异。结果显示,外表焦虑、创伤后成长和感知到的社会支持之间存在负相关。此外,创伤后成长与感知社会支持之间存在显著的正相关。结果表明,颌面部创伤患者的创伤后成长和感知社会支持与社会排斥呈负相关。研究结果表明,创伤后成长在颌面部创伤患者外表焦虑与社会排斥的关系中起中介作用,而感知到的社会支持调节了二者之间的关系。本研究将促进创伤恢复的多方面方法和干预,以改善颌面创伤患者的整体健康。
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引用次数: 0
Acne, self-esteem, and mental health: a scoping review. 痤疮、自尊和心理健康:范围界定综述。
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-02-15 DOI: 10.1080/13548506.2025.2465655
Barbara Faro, Brenda Silva-Ferraz, Andre Faro

Acne vulgaris is one of the most common skin diseases worldwide, with a prevalence ranging from 20-95%. Given the effect of acne on one's psychological well-being, investigating this relationship is important. This review aims to synthesize the main findings on the relationship between acne, self-esteem, and mental health. The SciELO, PubMed, PsycINFO, Scopus, and Web of Science databases were searched. We used the Joanna Briggs Institute methodology for scoping reviews and the PRISMA protocol and Rayyan tool for the selection and inclusion of studies. The terms used in the electronic search were 'acne' and 'self-esteem'. After reading the abstracts and applying the inclusion and exclusion criteria, 10 studies were selected for quantitative synthesis. The findings of this study indicate that patients with acne experience more mental health disorders, with their subjective perceptions linked to depression, anxiety, and incapacity. Females tend to have lower self-esteem, and their assessments vary depending on the evaluation method used. These results clarify the relationship between acne, self-esteem, and mental health. Furthermore, they provide evidence of factors that increase vulnerability to psychological impacts associated with acne. In conclusion, the literature emphasizes the importance of ongoing research on acne, its impact on self-esteem, and its relationship with other psychological dimensions. While acne is not lethal, it can be disabling, lead to suffering, and negatively affect daily functioning. Effective treatment of this condition requires an integrated approach that combines medical and psychological care.

寻常痤疮是世界上最常见的皮肤病之一,患病率在20-95%之间。考虑到痤疮对心理健康的影响,研究这种关系是很重要的。本文综述了痤疮、自尊和心理健康之间关系的主要研究成果。检索了SciELO、PubMed、PsycINFO、Scopus和Web of Science数据库。我们使用乔安娜布里格斯研究所的方法进行范围审查,使用PRISMA协议和Rayyan工具选择和纳入研究。电子搜索的关键词是“痤疮”和“自尊”。在阅读摘要并应用纳入和排除标准后,选择10项研究进行定量综合。这项研究的结果表明,痤疮患者会经历更多的精神健康障碍,他们的主观认知与抑郁、焦虑和丧失能力有关。女性往往有较低的自尊心,她们的评估因所使用的评估方法而异。这些结果阐明了痤疮、自尊和心理健康之间的关系。此外,他们还提供了与痤疮相关的因素增加易受心理影响的证据。总之,文献强调了正在进行的痤疮研究的重要性,它对自尊的影响,以及它与其他心理维度的关系。虽然痤疮不是致命的,但它会导致残疾,导致痛苦,并对日常功能产生负面影响。这种情况的有效治疗需要将医疗和心理护理相结合的综合方法。
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引用次数: 0
The mediating role of digital addiction in the relationship between cognitive disengagement syndrome and problem-solving skills. 数字成瘾在认知脱离综合征与解决问题能力关系中的中介作用。
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-02-21 DOI: 10.1080/13548506.2025.2469190
Osman Tayyar Çelik, Cihangir Kaçmaz

Background: There is a growing interest in the effects of Cognitive Disengagement Syndrome (CDS) on children. Despite concerns about the effects of CDS on cognitive abilities, especially in children, research is quite limited. It is important to understand the mechanisms of CDS on problem-solving skills.

Aim: This study aims to investigate the relationship of CDS with problem solving skills in children and also to examine the potential mediating role of digital addiction.

Method: The study was cross-sectional research involving 433 middle school children aged 11 and 14.

Results: Our results showed that there were positive relationships between CDS and digital addiction, negative relationships between CDS and problem solving skills, and negative relationships between digital addiction and problem solving skills. Moreover, our findings suggest that CDS is associated with problem-solving skills both directly and indirectly through digital addiction.

Conclusion: Intervention programs developed for children with or at risk of CDS should incorporate practices to enhance problem-solving skills and behavioral interventions to balance their use of digital tools.

背景:认知脱离综合症(CDS)对儿童的影响越来越引起人们的兴趣。尽管人们担心CDS对认知能力的影响,尤其是对儿童的影响,但研究相当有限。了解CDS对解决问题能力的作用机制是很重要的。目的:本研究旨在探讨儿童cd与问题解决能力的关系,并探讨数字成瘾的潜在中介作用。方法:采用横断面研究方法,对433名11 ~ 14岁中学生进行调查。结果:CDS与数字成瘾呈正相关,CDS与问题解决能力呈负相关,数字成瘾与问题解决能力呈负相关。此外,我们的研究结果表明,cd与通过数字成瘾直接或间接地解决问题的能力有关。结论:为患有或有CDS风险的儿童制定的干预方案应包括提高解决问题能力和行为干预的实践,以平衡他们对数字工具的使用。
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引用次数: 0
Exploring the impact of technology on traditional Chinese medicine in the RCEP framework: innovation, sustainability, and economic growth. 在RCEP框架下探讨技术对中医药的影响:创新、可持续性和经济增长。
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-07-13 DOI: 10.1080/13548506.2025.2522930
Chanting Chen, Xiaoxiao Huang, Xiangcheng Zhou

The Regional Comprehensive Economic Partnership (RCEP) brings together Asia-Pacific nations to enhance economic ties. Traditional Chinese Medicine (TCM) faces changes due to Technological Innovation (TI), presenting economic opportunities and challenges for member states. This study explored the impacts of technology on TCM production and exportation within the RCEP framework. A purposive sampling technique is used in this study to choose the samples for data collection. Utilizing a mixed method approach, valid responses were gathered from 450 participants. The collected data were subjected to analysis using the Statistical Package for the Social Sciences (SPSS) software. The study revealed that TI in TCM production indeed has significant positive implications for RCEP member states. The study found that the adoption of advanced technology in TCM production promotes innovation and sustainability within the industry, driving long-term growth for RCEP member states. The study highlights the potential for RCEP member states to leverage their collective expertise and resources to establish themselves as leaders in the global TCM industry, creating new avenues for economic development and cooperation. The study's contribution lies in highlighting how technology in TCM production can boost economic resilience and competitiveness within the RCEP framework, emphasizing its role in fostering collaboration and knowledge-sharing among member states.

区域全面经济伙伴关系协定(RCEP)将亚太国家聚集在一起,加强经济联系。由于技术创新(TI),中医药(TCM)面临着变化,为成员国带来了经济机遇和挑战。本研究探讨了技术对RCEP框架下中药生产和出口的影响。本研究采用目的性抽样技术来选择样本进行数据收集。利用混合方法,从450名参与者中收集了有效的回答。收集的数据使用社会科学统计软件包(SPSS)软件进行分析。研究表明,中药生产中的TI确实对RCEP成员国具有显著的积极影响。研究发现,在中药生产中采用先进技术促进了行业内的创新和可持续性,推动了RCEP成员国的长期增长。该研究强调,RCEP成员国有潜力利用其集体专业知识和资源,使自己成为全球中医药产业的领导者,为经济发展和合作创造新的途径。该研究的贡献在于强调了中药生产中的技术如何在RCEP框架内提高经济弹性和竞争力,强调了其在促进成员国之间的合作和知识共享方面的作用。
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引用次数: 0
The role of depressive symptoms and self-efficacy in the relationship between activities of daily living and medication adherence among the elderly with chronic diseases: a serial mediation model. 老年慢性病患者抑郁症状和自我效能感在日常生活活动与药物依从性关系中的作用:一个系列中介模型
IF 1.9 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2026-01-01 Epub Date: 2025-03-17 DOI: 10.1080/13548506.2025.2478659
Yong Yu, Qianyu Huang, Keke Qin

The current study aimed to test the effects of depressive symptoms and self-efficacy in the relationship between activities of daily living (ADLs) and medication adherence using a serial mediation model. This cohort study was conducted among 797 elderly with chronic diseases in Hunan Province of China. Their ADLs, medication adherence, self-efficacy, and depressive symptoms were assessed by the Barthel Index (BI), the Morisky Medication Adherence Scale (MMAS-8), the Self-Efficacy for Appropriate Medication Use Scale (SEAMS), and the 20-item Center for Epidemiologic Studies Depression Scale (CES-D), respectively. The PROCESS SPSS Macro version 4.1, model 6, was used to test the serial mediation model of ADLs affecting medication adherence through self-efficacy and depressive symptoms. From baseline to follow-up, the elderly had a significant increase in depressive symptoms (from 15.3 ± 11.3 to 19.1 ± 13.1) and significant decreases in ADLs (from 71.4 ± 19.8 to 64.9 ± 17.61), self-efficacy (from 21.5 ± 5.4 to 20.4 ± 6.2), and medication adherence (from 6.7 ± 1.8 to 6.0 ± 1.5), all with p < 0.001. The serial mediation model demonstrated a robust association between ADLs and medication adherence, which was serially mediated by depressive symptoms and self-efficacy (total effect c = 0.499, 95% CI = 0.393 to 0.605; direct effect c' = 0.379, 95% CI = 0.281 to 0.477; total indirect effect ab = 0.120, 95% CI = 0.073 to 0.168). This study elucidates the association between ADL and medication adherence, clarifying the mediating roles of depressive symptoms and self-efficacy. Our findings suggest that future medication adherence intervention programs among the elderly with chronic illness may be effective by focusing on decreasing depressive symptoms and improving self-efficacy.

本研究旨在通过系列中介模型检验抑郁症状和自我效能在日常生活活动(ADLs)与药物依从性之间的作用。本队列研究在中国湖南省797名老年慢性病患者中进行。分别采用Barthel指数(BI)、Morisky药物依从性量表(MMAS-8)、适当药物使用自我效能量表(seam)和20项流行病学研究中心抑郁量表(CES-D)对其ADLs、药物依从性、自我效能感和抑郁症状进行评估。采用PROCESS SPSS Macro 4.1版模型6检验adl通过自我效能感和抑郁症状影响药物依从性的串行中介模型。从基线到随访,老年人抑郁症状显著增加(从15.3±11.3到19.1±13.1),adl显著降低(从71.4±19.8到64.9±17.61),自我效能感显著降低(从21.5±5.4到20.4±6.2),药物依从性显著降低(从6.7±1.8到6.0±1.5),p < 0.05
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引用次数: 0
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Psychology Health & Medicine
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