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Challenges with Defining Pharmaceutical Markets and Potential Remedies to Screen for Industry Consolidation. 定义药品市场的挑战和筛选行业整合的潜在补救措施。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-05-06 DOI: 10.1215/03616878-9978131
Robin C. Feldman, Brent D. Fulton, Jamie R. Godwin, R. Scheffler
CONTEXTDramatic increases in pharmaceutical merger and acquisition activity since 2010 suggest we are currently in the midst of a third wave of industry consolidation.METHODSReviewing 168 economic, legal, medical, industry, and government sources, we examine the effects of consolidation on competition and innovation and explore how industry attributes complicate M&A regulation in a pharmaceutical context.FINDINGSWe find that, in spite of certain metrics that might argue otherwise, consolidation consistently reduces innovation and harms the public good. We also find that several factors within the pharmaceutical industry impede proper evaluation of proposed mergers. Because consumer choice across substitutes is limited, pharmaceutical markets frustrate conventional methods of defining markets. Volume bargaining in the pharmaceutical supply chain and common ownership of pharmaceutical firms by asset managers further complicate the definitional process. Hence, the Herfindahl-Hirschman Index (HHI), one measure used by the Federal Trade Commission and Department of Justice to screen for concerning M&A activity, sometimes depends on faulty market definitions but also fails to capture the implications of consolidation on future market share.CONCLUSIONSWe describe ways to improve how pharmaceutical markets are defined, highlight quantitative alterations to HHI to account for common ownership, and propose areas requiring further research.
自2010年以来,制药行业并购活动的急剧增加表明,我们目前正处于第三波行业整合浪潮中。方法回顾了168个经济、法律、医疗、行业和政府来源,我们考察了整合对竞争和创新的影响,并探讨了行业属性如何使制药环境下的并购监管复杂化。我们发现,尽管某些指标可能会反驳,但整合始终会减少创新并损害公共利益。我们还发现,制药行业内部的几个因素阻碍了对拟议合并的适当评估。由于消费者在替代品之间的选择是有限的,药品市场挫败了传统的定义市场的方法。药品供应链中的批量议价和资产管理公司对制药公司的共同所有权进一步使定义过程复杂化。因此,赫芬达尔-赫希曼指数(HHI)——美国联邦贸易委员会和司法部用来筛选并购活动的一种指标——有时依赖于错误的市场定义,但也未能捕捉到整合对未来市场份额的影响。我们描述了改进药品市场定义的方法,强调了HHI的定量变化以解释共同所有权,并提出了需要进一步研究的领域。
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引用次数: 0
The Link between Democratic Institutions and Population Health in the American States. 美洲各州民主制度与人口健康之间的联系。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-05-06 DOI: 10.1215/03616878-9978103
Julianna Pacheco, Scott J. LaCombe
CONTEXTThis project investigates the role of state-level institutions in explaining variation in population health in the American states. Although cross-national research has established the positive effects of democracy on population health, little attention has been given to subnational units. We leverage a new dataset to understand how political accountability and a system of checks and balances are associated with state population health.METHODWe estimate error correction models and two-way fixed effects models to estimate how the strength of state-level democratic institutions are associated with infant mortality rates, life expectancy, and midlife mortality.FINDINGSWe find that institutions that promote political accountability are related to lower infant mortality across the states, while those that promote checks and balances are associated with longer life expectancy. We also find that policy liberalism is associated with better health outcomes.CONCLUSIONSSubnational institutions play an important role in population health outcomes and more research is needed to understand the linkage between democracy and health. We are the first to explore the link between democratic institutions and population health within the United States contributing to both the social science literature on the positive effects of democracy and the epidemiological literature on subnational health outcomes.
本项目调查州级机构在解释美国各州人口健康变化方面的作用。虽然跨国研究确定了民主对人口健康的积极影响,但很少注意到次国家单位。我们利用一个新的数据集来了解政治问责制和制衡制度如何与州人口健康相关联。方法我们估计误差修正模型和双向固定效应模型,以估计州级民主制度的强度与婴儿死亡率、预期寿命和中年死亡率之间的关系。我们发现,促进政治问责的制度与各州较低的婴儿死亡率有关,而促进制衡的制度与较长的预期寿命有关。我们还发现,政策自由主义与更好的健康结果有关。结论地方机构在人口健康结果中发挥着重要作用,需要更多的研究来了解民主与健康之间的联系。我们率先在美国境内探索民主制度与人口健康之间的联系,为有关民主的积极影响的社会科学文献和有关次国家卫生结果的流行病学文献做出了贡献。
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引用次数: 1
Ultimate Price: The Value We Place on Life 终极价格:我们赋予生命的价值
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-05-06 DOI: 10.1215/03616878-9978159
D. Weimer
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引用次数: 1
The Political Realignment of Health: How Partisan Power Shaped Infant Health in the United States, 1915-2017. 健康的政治调整:党派权力如何塑造美国的婴儿健康(1915-2017 年)》(The Political Realignment of Health: How Partisan Power Shaped Infant Health in the United States, 1915-2017)。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9517191
Javier M Rodríguez, Byengseon Bae, Arline T Geronimus, John Bound

The US two-party system was transformed in the 1960s when the Democratic Party abandoned its Jim Crow protectionism to incorporate the policy agenda fostered by the civil rights movement, and the Republican Party redirected its platform toward socioeconomic and racial conservatism. The authors argue that the policy agendas promoted by the two parties through presidents and state legislatures codify a racially patterned access to resources and power detrimental to the health of all. To test the hypothesis that fluctuations in overall and race-specific infant mortality rates (IMRs) shift between the parties in power before and after the political realignment (PR), the authors apply panel data analysis methods to state-level data from the National Center for Health Statistics for the period 1915 through 2017. Net of trend, overall, and race-specific IMRs were not statistically different between presidential parties before the PR. This pattern, however, changed after the PR, with Republican administrations consistently underperforming Democratic ones. Net of trend, non-Southern state legislatures controlled by Republicans underperform Democratic ones in overall and racial IMRs in both periods.

20 世纪 60 年代,美国两党制发生了转变,民主党放弃了吉姆-克罗保护主义,将民权运动推动的政策议程纳入其中,而共和党则将其政纲转向社会经济和种族保守主义。作者认为,两党通过总统和州立法机构推行的政策议程将种族模式化的资源和权力获取方式编纂成法律,不利于所有人的健康。为了检验政治调整(PR)前后总体婴儿死亡率和特定种族婴儿死亡率(IMRs)的波动在执政党之间发生转移这一假设,作者将面板数据分析方法应用于国家卫生统计中心提供的 1915 年至 2017 年期间的州一级数据。除去趋势因素,在政治调整之前,各总统政党之间的总体和种族IMR并无统计学差异。然而,这一模式在总统选举后发生了变化,共和党政府的表现始终低于民主党政府。扣除趋势因素,由共和党控制的非南方州立法机构在两个时期的总体和种族 IMR 均低于民主党立法机构。
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引用次数: 0
State Policies, Racial Disparities, and Income Support: A Way to Address Infant Outcomes and the Persistent Black-White Gap? 州政策、种族差异和收入支持:解决婴儿成绩和持续存在的黑白差距的方法?
IF 3.3 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9517205
Jessica Pearlman, Dean E Robinson

Low birth weight and preterm births vary by state, and Black mothers typically face twice the risk that their white counterparts do. This gap reflects an accumulation of psychosocial and material exposures that include interpersonal racism, differential experience with area-level deprivation such as residential segregation, and other harmful exposures that the authors refer to as "institutional" or "structural" racism. The authors use logistic regression models and a dataset that includes all births from 1994 to 2017 as well as five state policies from this period-Aid to Families with Dependent Children/Temporary Aid for Needy Families, housing assistance, Medicaid, minimum wage, and the earned income tax credit (EITC)-to examine whether these state social policies, designed to provide a financial safety net, are associated with risk reduction of low birth weight and preterm birth to Black and white mothers, and whether variations in state generosity attenuate the racial inequalities in birth outcomes. The authors also examine whether the relationship between state policies and racial inequalities in birth outcomes is moderated by the education level of the mother. We find that the EITC reduces the risk of low birth weight and preterm birth for Black mothers. The impact is much less consistent for white mothers. For both Black and white mothers, the benefits to birth outcomes are larger for mothers with less education.

出生体重不足和早产的情况因州而异,黑人母亲面临的风险通常是白人母亲的两倍。这种差距反映了社会心理和物质暴露的累积,其中包括人际种族主义、地区级剥夺(如住宅隔离)的不同经历,以及作者称之为 "制度性 "或 "结构性 "种族主义的其他有害暴露。作者使用逻辑回归模型和数据集,数据集包括 1994 年至 2017 年的所有新生儿以及这一时期的五项州政策--对有受抚养子女家庭的援助/对贫困家庭的临时援助、住房援助、医疗补助、最低工资以及收入所得税抵免(EE)、和所得税抵免(EITC)--以研究这些旨在提供经济安全网的州社会政策是否与降低黑人和白人母亲的低出生体重和早产风险有关,以及州慷慨程度的变化是否会减轻出生结果中的种族不平等。作者还研究了州政策与出生结果种族不平等之间的关系是否会受到母亲教育水平的影响。我们发现,EITC 降低了黑人母亲出生体重不足和早产的风险。对白人母亲的影响则不那么一致。对于黑人和白人母亲而言,教育程度较低的母亲对出生结果的益处更大。
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引用次数: 0
No Equity without Data Equity: Data Reporting Gaps for Native Hawaiians and Pacific Islanders as Structural Racism. 没有数据公平就没有公平:夏威夷原住民和太平洋岛民的数据报告差距是结构性种族主义。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9517177
Brittany N Morey, Richard Calvin Chang, Karla Blessing Thomas, 'Alisi Tulua, Corina Penaia, Vananh D Tran, Nicholas Pierson, John C Greer, Malani Bydalek, Ninez Ponce

Data on the health and social determinants for Native Hawaiians and Pacific Islanders (NHPIs) in the United States are hidden, because data are often not collected or are reported in aggregate with other racial/ethnic groups despite decades of calls to disaggregate NHPI data. As a form of structural racism, data omissions contribute to systemic problems such as inability to advocate, lack of resources, and limitations on political power. The authors conducted a data audit to determine how US federal agencies are collecting and reporting disaggregated NHPI data. Using the COVID-19 pandemic as a case study, they reviewed how states are reporting NHPI cases and deaths. They then used California's neighborhood equity metric-the California Healthy Places Index (HPI)-to calculate the extent of NHPI underrepresentation in communities targeted for COVID-19 resources in that state. Their analysis shows that while collection and reporting of NHPI data nationally has improved, federal data gaps remain. States are vastly underreporting: more than half of states are not reporting NHPI COVID-19 case and death data. The HPI, used to inform political decisions about allocation of resources to combat COVID-19 in at-risk neighborhoods, underrepresents NHPIs. The authors make recommendations for improving NHPI data equity to achieve health equity and social justice.

有关美国夏威夷原住民和太平洋岛民(NHPIs)的健康和社会决定因素的数据是隐性的,因为尽管数十年来人们一直呼吁对夏威夷原住民和太平洋岛民的数据进行分类,但这些数据往往没有被收集或与其他种族/族裔群体的数据合并报告。作为结构性种族主义的一种形式,数据遗漏导致了系统性问题,如无法宣传、缺乏资源和政治权力受限。作者进行了一次数据审计,以确定美国联邦机构是如何收集和报告分类的非高危人群数据的。他们以 COVID-19 大流行为案例,审查了各州如何报告非高危人群病例和死亡人数。然后,他们使用加利福尼亚州的邻里公平指标--加利福尼亚州健康场所指数 (HPI)--计算了该州 COVID-19 资源目标社区中 NHPI 代表性不足的程度。他们的分析表明,虽然全国范围内对 NHPI 数据的收集和报告有所改善,但联邦数据缺口依然存在。各州的报告严重不足:半数以上的州没有报告 NHPI COVID-19 病例和死亡数据。HPI 用于为政治决策提供信息,以分配资源在高风险社区抗击 COVID-19,但它对 NHPI 的代表不足。作者提出了改善 NHPI 数据公平性的建议,以实现健康公平和社会正义。
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引用次数: 0
Mexican-Origin Women's Construction and Navigation of Racialized Identities: Implications for Health Amid Restrictive Immigrant Policies. 墨西哥裔妇女种族化身份的建构与导航:限制移民政策对健康的影响。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9518665
Alana M W LeBrón, Amy J Schulz, Cindy Gamboa, Angela Reyes, Edna Viruell-Fuentes, Barbara A Israel

This study examines how Mexican-origin women construct and navigate racialized identities in a postindustrial northern border community during a period of prolonged restrictive immigration and immigrant policies, and it considers mechanisms by which responses to racialization may shape health. This grounded theory analysis involves interviews with 48 Mexican-origin women in Detroit, Michigan, who identified as being in the first, 1.5, or second immigrant generation. In response to institutions and institutional agents using racializing markers to assess their legal status and policing access to health-promoting resources, women engaged in a range of strategies to resist being constructed as an "other." Women used the same racializing markers or symbols of (il)legality that had been used against them as a malleable set of resources to resist processes of racialization and to form, preserve, and affirm their identities. These responses include constructing an authorized immigrant identity, engaging in immigration advocacy, and resisting stigmatizing labels. These strategies may have different implications for health over time. Findings indicate the importance of addressing policies that promulgate or exacerbate racialization of Mexican-origin communities and other communities who experience growth through migration. Such policies include creating pathways to legalization and access to resources that have been invoked in racialization processes, such as state-issued driver's licenses.

本研究考察了在长期限制移民和移民政策时期,墨西哥裔妇女如何在后工业时代的北部边境社区构建和导航种族化身份,并考虑了对种族化的反应可能影响健康的机制。这一理论分析包括对密歇根州底特律市48名墨西哥裔女性的采访,她们被认为是第一代、第1.5代或第二代移民。针对一些机构和机构代理人使用种族化标记来评估她们的法律地位和监督她们获得促进健康的资源的情况,妇女采取了一系列战略,以抵制被建构为"他者"。妇女使用同样的种族化标记或(非)合法性的符号,这些符号曾经被用来反对她们,作为一套可塑的资源来抵制种族化的过程,形成、保存和确认她们的身份。这些应对措施包括建立合法的移民身份,参与移民宣传,以及抵制污名化的标签。随着时间的推移,这些策略可能对健康产生不同的影响。研究结果表明,解决政策的重要性,这些政策颁布或加剧了墨西哥裔社区和其他通过移民经历增长的社区的种族化。这些政策包括创造合法化的途径,并获得在种族化过程中调用的资源,例如国家颁发的驾驶执照。
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引用次数: 2
Racism, Health, and Politics: Advancing Interdisciplinary Knowledge. 种族主义、健康和政治:推进跨学科知识。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9517149
Jamila Michener, Alana M W LeBrón
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引用次数: 4
What Is a "Racial Health Disparity"? Five Analytic Traditions. 什么是“种族健康差异”?五种分析传统。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-04-01 DOI: 10.1215/03616878-9517163
Merlin Chowkwanyun

What exactly is a "racial health disparity"? This article explores five lenses that have been used to answer that question. It contends that racial health disparities have been presented-by researchers both within academia and outside of it-as problems of five varieties: biology, behavior, place, stress, and policy. It also argues that a sixth tradition exploring class-and its connection to race, racism, and health-has been underdeveloped. The author examines each of these conceptions of racial disparities in turn. Baked into each interpretive prism is a set of assumptions about the mechanisms that produce disparities-a story, in other words, about where racial health disparities come from. Discursive boundaries set the parameters for policy debate, determining what is and is not included in proposed solutions. How one sees racial health disparities, then, influences the strategies a society advocates-or ignores-for their elimination. The author ends by briefly discussing problems in the larger research ecosystem that dictate how racial health disparities are studied.

“种族健康差异”究竟是什么?本文探讨了五个用来回答这个问题的镜头。它认为,学术界内外的研究人员都提出了种族健康差异的五个方面的问题:生物学、行为、地域、压力和政策。它还认为,探索阶级及其与种族、种族主义和健康的联系的第六个传统尚未得到发展。作者依次考察了这些种族差异的概念。每种解释的棱镜都包含了一系列关于产生差异的机制的假设——换句话说,这是一个关于种族健康差异从何而来的故事。话语边界为政策辩论设定了参数,决定了建议的解决方案中应该包括什么,不应该包括什么。因此,一个人如何看待种族健康差异,会影响一个社会倡导或忽视消除种族健康差异的策略。作者最后简要讨论了在更大的研究生态系统中决定如何研究种族健康差异的问题。
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引用次数: 2
Born in the USA? A Comparison of "Inspired" Health Care Reforms in Germany and France. 出生在美国?德国和法国“启发式”医疗改革的比较。
IF 4.2 3区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2022-02-01 DOI: 10.1215/03616878-9417442
Matthias Brunn

Context: Despite numerous examples of health policy transfer in Western health systems, the nature of such "inspired" reforms has received little detailed attention. The aim of this article is to apply and refine a specific theoretical angle for the analysis of these reforms using the theoretical frameworks of transfer and translation.

Methods: The design is based on a comparative case study: the introduction of disease management programs (DMPs) for diabetes in Germany in 2002 and in France in 2008, drawing on a literature review and semistructured interviews.

Findings: In introducing its DMP, Germany chose and combined several components in a process of selective borrowing, while France opted for copying a specific foreign program and adapting it. Such differences in process are linked to distinct system structures, in particular the setup of health insurance and the representation of physicians. Furthermore, the displayed versus actual degree of inspiration varied significantly, with a branding strategy in Germany (high display of foreign influence) and the inverse picture in France (high degree of actual inspiration).

Conclusions: This analysis has applied the dual perspective of transfer and translation. Both perspectives proved complementary and necessary, and translation appeared as a main determinant of implementation success.

背景:尽管西方卫生系统中有许多卫生政策转移的例子,但这种“灵感”改革的性质很少得到详细关注。本文的目的是运用迁移和翻译的理论框架,为分析这些改革提供一个具体的理论视角。方法:设计基于一个比较案例研究:2002年在德国和2008年在法国引入糖尿病疾病管理计划(dmp),借鉴文献综述和半结构化访谈。研究发现:在引进DMP的过程中,德国在选择性借鉴的过程中选择并结合了几个组成部分,而法国选择复制特定的外国项目并进行调整。这种过程上的差异与不同的制度结构有关,特别是医疗保险的设置和医生的代表。此外,展示的灵感程度与实际的灵感程度差异很大,德国的品牌策略(高度展示外国影响力)和法国的情况相反(高度实际的灵感)。结论:本研究采用了迁移和翻译的双重视角。这两种观点证明是相互补充和必要的,翻译似乎是执行成功的主要决定因素。
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引用次数: 0
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Journal of Health Politics Policy and Law
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