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The influence of pre-injury anticoagulant or antiplatelet agents on outcomes in trauma patients sustaining abdominal solid organ injuries: A scoping review
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-17 DOI: 10.1016/j.injury.2025.112175
Gi Young Seo , Arpita Das , Silvia Manzanero , Keeyeon Kim , Carl Lisec , Michael Muller

Background

Indications for, and usage of, anticoagulant (AC) and antiplatelet (AP) agents is increasing. In this context, it is important to understand the evidence base of the effect of pre-injury AC/AP agents on patient outcomes in the context of traumatic solid organ injury (SOI) to inform management protocols.

Methods

A scoping review of the literature was undertaken with a systematic search strategy within the PubMed and Scopus databases. Study characteristics, clinical outcomes and outcome measures including mortality, hospital length of stay, admission to intensive care units, length of stay in intensive care and management details were extracted from included studies.

Results

The search identified six eligible studies reporting results from a total of 26,960 patients. Patients on AC/AP are more likely to fail non-operative management (NOM) than their non-AC/AP counterparts; at the same time, they are less likely to be operated on as a first line of management. Clinical outcome measures (mortality, length of stay, admission to intensive care units, and length of intensive care unit stay) were heterogeneous across studies, but it is likely that AC/AP patients have poorer outcomes in SOI. Results on transfusion requirements were inconclusive.

Conclusion

Few studies have examined the effect of pre-injury anticoagulation on outcomes in trauma patients sustaining solid organ injuries. Future studies should more closely examine solid organ trauma within the elderly group, as well as the effect of newer AC/AP agents in current use.
{"title":"The influence of pre-injury anticoagulant or antiplatelet agents on outcomes in trauma patients sustaining abdominal solid organ injuries: A scoping review","authors":"Gi Young Seo ,&nbsp;Arpita Das ,&nbsp;Silvia Manzanero ,&nbsp;Keeyeon Kim ,&nbsp;Carl Lisec ,&nbsp;Michael Muller","doi":"10.1016/j.injury.2025.112175","DOIUrl":"10.1016/j.injury.2025.112175","url":null,"abstract":"<div><h3>Background</h3><div>Indications for, and usage of, anticoagulant (AC) and antiplatelet (AP) agents is increasing. In this context, it is important to understand the evidence base of the effect of pre-injury AC/AP agents on patient outcomes in the context of traumatic solid organ injury (SOI) to inform management protocols.</div></div><div><h3>Methods</h3><div>A scoping review of the literature was undertaken with a systematic search strategy within the PubMed and Scopus databases. Study characteristics, clinical outcomes and outcome measures including mortality, hospital length of stay, admission to intensive care units, length of stay in intensive care and management details were extracted from included studies.</div></div><div><h3>Results</h3><div>The search identified six eligible studies reporting results from a total of 26,960 patients. Patients on AC/AP are more likely to fail non-operative management (NOM) than their non-AC/AP counterparts; at the same time, they are less likely to be operated on as a first line of management. Clinical outcome measures (mortality, length of stay, admission to intensive care units, and length of intensive care unit stay) were heterogeneous across studies, but it is likely that AC/AP patients have poorer outcomes in SOI. Results on transfusion requirements were inconclusive.</div></div><div><h3>Conclusion</h3><div>Few studies have examined the effect of pre-injury anticoagulation on outcomes in trauma patients sustaining solid organ injuries. Future studies should more closely examine solid organ trauma within the elderly group, as well as the effect of newer AC/AP agents in current use.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112175"},"PeriodicalIF":2.2,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osseointegration for transfemoral amputees: Influence of femur length and implant sizing on bone-implant contact and alignment
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-17 DOI: 10.1016/j.injury.2025.112162
Matthew Cao , David B. Doherty , Hongjia He , Vinay P. Vanodia , Kristin Reeves , Sabir K. Ismaily , Jonathan J. Sauer , Shuyang Han

Introduction

Clinical data on osseointegration (OI) for limb replacement indicates a concerning increase in mechanical complications after five years post-implantation. Since adequate bone-implant contact and proper implant alignment are critical factors for successful osseointegration, it is essential to identify the factors influencing these outcomes. This study aimed to assess the effects of residual femur length and implant sizing on bone-implant contact and implant alignment.

Methods

Three-dimensional models of eight cadaveric femora were reconstructed from CT scans, and transfemoral amputations were simulated for each femur at three levels: short (ST: 1/3 L), medium (MD: 1/2 L), and long (LG: 2/3 L). Virtual OI surgeries were then performed using computer-aided design (CAD) models, and implant sizes were recorded. Subsequently, the effect of implant sizing was assessed by adjusting the implant size by ±1 mm. Contact length and implant alignment were compared between the groups using repeated measures analysis of variance with Bonferroni correction.

Results

The contact in the ST group (65.2 ± 7.3 %) was significantly less compared to the MD (96.1 ± 4.1 %, p < 0.001) and LG (96.8 ± 3.2 %, p < 0.001) groups. Upsizing increased contact in the ST group by 7.0 ± 2.6 % (p < 0.001), though it did not reach levels comparable to the MD and LG groups (p > 0.05). Additionally, sagittal implant misalignment was larger in the ST group (10.1 ± 2.0°) than in the MD (7.9 ± 1.5°) and LG (3.5 ± 1.6°) groups (p < 0.001), while no difference was observed in coronal implant alignment.

Conclusion

These findings highlight the factors influencing mechanical complications of osseointegration implants and provide a basis for refined implant designs and surgical techniques for patients with short residual limbs.
{"title":"Osseointegration for transfemoral amputees: Influence of femur length and implant sizing on bone-implant contact and alignment","authors":"Matthew Cao ,&nbsp;David B. Doherty ,&nbsp;Hongjia He ,&nbsp;Vinay P. Vanodia ,&nbsp;Kristin Reeves ,&nbsp;Sabir K. Ismaily ,&nbsp;Jonathan J. Sauer ,&nbsp;Shuyang Han","doi":"10.1016/j.injury.2025.112162","DOIUrl":"10.1016/j.injury.2025.112162","url":null,"abstract":"<div><h3>Introduction</h3><div>Clinical data on osseointegration (OI) for limb replacement indicates a concerning increase in mechanical complications after five years post-implantation. Since adequate bone-implant contact and proper implant alignment are critical factors for successful osseointegration, it is essential to identify the factors influencing these outcomes. This study aimed to assess the effects of residual femur length and implant sizing on bone-implant contact and implant alignment.</div></div><div><h3>Methods</h3><div>Three-dimensional models of eight cadaveric femora were reconstructed from CT scans, and transfemoral amputations were simulated for each femur at three levels: short (ST: 1/3 L), medium (MD: 1/2 L), and long (LG: 2/3 L). Virtual OI surgeries were then performed using computer-aided design (CAD) models, and implant sizes were recorded. Subsequently, the effect of implant sizing was assessed by adjusting the implant size by ±1 mm. Contact length and implant alignment were compared between the groups using repeated measures analysis of variance with Bonferroni correction.</div></div><div><h3>Results</h3><div>The contact in the ST group (65.2 ± 7.3 %) was significantly less compared to the MD (96.1 ± 4.1 %, <em>p</em> &lt; 0.001) and LG (96.8 ± 3.2 %, <em>p</em> &lt; 0.001) groups. Upsizing increased contact in the ST group by 7.0 ± 2.6 % (<em>p</em> &lt; 0.001), though it did not reach levels comparable to the MD and LG groups (<em>p</em> &gt; 0.05). Additionally, sagittal implant misalignment was larger in the ST group (10.1 ± 2.0°) than in the MD (7.9 ± 1.5°) and LG (3.5 ± 1.6°) groups (<em>p</em> &lt; 0.001), while no difference was observed in coronal implant alignment.</div></div><div><h3>Conclusion</h3><div>These findings highlight the factors influencing mechanical complications of osseointegration implants and provide a basis for refined implant designs and surgical techniques for patients with short residual limbs.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112162"},"PeriodicalIF":2.2,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunistic screening for metabolic bone disease in high energy fracture patients
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-17 DOI: 10.1016/j.injury.2025.112147
Garrett Gordon , Brian Johnson , Olivia Marquardt , Dylan Young , Michael J. Beltran , Sarah N. Pierrie

Objective

Metabolic bone disease (MBD, referring to osteopenia and osteoporosis) and its sequelae are associated with substantial morbidity, mortality, and healthcare costs. MBD screening and bone densitometry referral are underutilized in the general population despite published screening guidelines. Prior studies have correlated vertebral body Hounsfield unit (HU) measurements with MBD. The purpose of this study is to use this method to identify the prevalence of undiagnosed MBD in patients presenting to the hospital after high energy trauma, and to determine whether opportunistic MBD screening using this method would be valuable in this cohort.

Design

Retrospective review.

Setting

Level 1 trauma center and safety net hospital.

Patients

307 patients with a high energy femur fracture who underwent abdomen/pelvis computed tomography (CT) were identified from a trauma database.

Intervention

L1 vertebral body radio density (in Hounsfield units, HU) was measured from trauma CT scans. Risk factors for MBD were identified from the medical record.

Main outcome measurements

Prevalence of MBD and proportion of patients with MBD risk factors meriting further work-up.

Results

The prevalence of MBD among high energy trauma patients was similar to the age-matched general population. Over half (50.5 %) of all patients had at least one risk factor for MBD. Among patients 50 to 64 years of age with any given MBD risk factor, over a third of individuals had MBD. In this population, the prevalence of MBD was highest (40.0 %) among those who used tobacco products and had a concurrent alcohol use disorder.

Conclusion

Opportunistic screening for MBD using a CT measurement technique can facilitate earlier diagnosis and treatment for affected individuals presenting after high energy trauma. Opportunistic screening may be particularly impactful in pre-menopausal women and in men, who frequently have MBD risk factors but who have a low referral rate for bone density testing and treatment.
Level of evidence: Diagnostic level III.
{"title":"Opportunistic screening for metabolic bone disease in high energy fracture patients","authors":"Garrett Gordon ,&nbsp;Brian Johnson ,&nbsp;Olivia Marquardt ,&nbsp;Dylan Young ,&nbsp;Michael J. Beltran ,&nbsp;Sarah N. Pierrie","doi":"10.1016/j.injury.2025.112147","DOIUrl":"10.1016/j.injury.2025.112147","url":null,"abstract":"<div><h3>Objective</h3><div>Metabolic bone disease (MBD, referring to osteopenia and osteoporosis) and its sequelae are associated with substantial morbidity, mortality, and healthcare costs. MBD screening and bone densitometry referral are underutilized in the general population despite published screening guidelines. Prior studies have correlated vertebral body Hounsfield unit (HU) measurements with MBD. The purpose of this study is to use this method to identify the prevalence of undiagnosed MBD in patients presenting to the hospital after high energy trauma, and to determine whether opportunistic MBD screening using this method would be valuable in this cohort.</div></div><div><h3>Design</h3><div>Retrospective review.</div></div><div><h3>Setting</h3><div>Level 1 trauma center and safety net hospital.</div></div><div><h3>Patients</h3><div>307 patients with a high energy femur fracture who underwent abdomen/pelvis computed tomography (CT) were identified from a trauma database.</div></div><div><h3>Intervention</h3><div>L1 vertebral body radio density (in Hounsfield units, HU) was measured from trauma CT scans. Risk factors for MBD were identified from the medical record.</div></div><div><h3>Main outcome measurements</h3><div>Prevalence of MBD and proportion of patients with MBD risk factors meriting further work-up.</div></div><div><h3>Results</h3><div>The prevalence of MBD among high energy trauma patients was similar to the age-matched general population. Over half (50.5 %) of all patients had at least one risk factor for MBD. Among patients 50 to 64 years of age with any given MBD risk factor, over a third of individuals had MBD. In this population, the prevalence of MBD was highest (40.0 %) among those who used tobacco products and had a concurrent alcohol use disorder.</div></div><div><h3>Conclusion</h3><div>Opportunistic screening for MBD using a CT measurement technique can facilitate earlier diagnosis and treatment for affected individuals presenting after high energy trauma. Opportunistic screening may be particularly impactful in pre-menopausal women and in men, who frequently have MBD risk factors but who have a low referral rate for bone density testing and treatment.</div><div>Level of evidence: Diagnostic level III.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112147"},"PeriodicalIF":2.2,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proxy-reported outcomes accurately reflect objective patient-reported outcomes in older adult patients with traumatic orthopaedic injuries
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-17 DOI: 10.1016/j.injury.2025.112163
N.H.M. Ponds , J.R. Raats , D.T. Brameier , H.J. Schuijt , D. van der Velde , M.J. Weaver

Background

Older adults make up an increasing portion of orthopedic trauma care. Proxy reports are particularly valuable when patients face difficulties formulating answers due to pre-existing or temporary cognitive impairment, and provide critical insights into patient well-being.

Questions/purposes

This study examines the agreement between patient- and proxy-reported outcome measures across various health domains of older adult orthopedic trauma patients, including those with mild cognitive impairment.

Patients and methods

A prospective cohort study was conducted in the Orthopedic trauma clinic of two Level 1 trauma centers, involving 108 patients aged 70 years or older, with or without mild cognitive impairment, and a self-identified discernible proxy. Participants were evaluated using PROMIS measures for physical function, pain intensity, anxiety, depression, fatigue, and social roles and (instrumental) activities of daily living questionnaires. Agreement between patient and proxy assessments was analyzed using Intraclass Correlation Coefficient and Bland-Altman analyses. Subgroup comparison was made using confidence intervals.

Results

Most patients were married women with a mean age of 78 years (SD 6.2), 61 % had higher education, 67 % were walking independently, and 53 % had fractures of the pelvic ring or femur. Proxies were younger (mean age 64 years, SD 15), with 41 % being children and 40 % spouses. Significant correlations were found between patient and proxy assessments in physical function (ICC 0.74, 95 % CI 0.61-0.82), pain intensity (ICC 0.83, 95 % CI 0.74-0.89), (instrumental) activities of daily living (both ICC 0.86, 95 % CI 0.80-0.91). Moderate correlations were observed in anxiety, depression, fatigue, and participation in social roles (ICCs ranging from 0.56 to 0.66). Bland-Altman analyses confirmed good agreement with none to minimal systematic bias across all these domains.

Conclusion

Proxy-reported outcomes are valuable for evaluating health domains in older adult orthopedic trauma patients, including those with cognitive impairments. While proxies reliably assess physical and pain-related domains, additional strategies are needed to improve accuracy in more subjective domains. Future research should explore longitudinal agreements to better understand recovery perceptions over time and mitigate bias proxy-reporting, ultimately enhancing both patient care and outcomes research in geriatric orthopedic trauma patients.
{"title":"Proxy-reported outcomes accurately reflect objective patient-reported outcomes in older adult patients with traumatic orthopaedic injuries","authors":"N.H.M. Ponds ,&nbsp;J.R. Raats ,&nbsp;D.T. Brameier ,&nbsp;H.J. Schuijt ,&nbsp;D. van der Velde ,&nbsp;M.J. Weaver","doi":"10.1016/j.injury.2025.112163","DOIUrl":"10.1016/j.injury.2025.112163","url":null,"abstract":"<div><h3>Background</h3><div>Older adults make up an increasing portion of orthopedic trauma care. Proxy reports are particularly valuable when patients face difficulties formulating answers due to pre-existing or temporary cognitive impairment, and provide critical insights into patient well-being.</div></div><div><h3>Questions/purposes</h3><div>This study examines the agreement between patient- and proxy-reported outcome measures across various health domains of older adult orthopedic trauma patients, including those with mild cognitive impairment.</div></div><div><h3>Patients and methods</h3><div>A prospective cohort study was conducted in the Orthopedic trauma clinic of two Level 1 trauma centers, involving 108 patients aged 70 years or older, with or without mild cognitive impairment, and a self-identified discernible proxy. Participants were evaluated using PROMIS measures for physical function, pain intensity, anxiety, depression, fatigue, and social roles and (instrumental) activities of daily living questionnaires. Agreement between patient and proxy assessments was analyzed using Intraclass Correlation Coefficient and Bland-Altman analyses. Subgroup comparison was made using confidence intervals.</div></div><div><h3>Results</h3><div>Most patients were married women with a mean age of 78 years (SD 6.2), 61 % had higher education, 67 % were walking independently, and 53 % had fractures of the pelvic ring or femur. Proxies were younger (mean age 64 years, SD 15), with 41 % being children and 40 % spouses. Significant correlations were found between patient and proxy assessments in physical function (ICC 0.74, 95 % CI 0.61-0.82), pain intensity (ICC 0.83, 95 % CI 0.74-0.89), (instrumental) activities of daily living (both ICC 0.86, 95 % CI 0.80-0.91). Moderate correlations were observed in anxiety, depression, fatigue, and participation in social roles (ICCs ranging from 0.56 to 0.66). Bland-Altman analyses confirmed good agreement with none to minimal systematic bias across all these domains.</div></div><div><h3>Conclusion</h3><div>Proxy-reported outcomes are valuable for evaluating health domains in older adult orthopedic trauma patients, including those with cognitive impairments. While proxies reliably assess physical and pain-related domains, additional strategies are needed to improve accuracy in more subjective domains. Future research should explore longitudinal agreements to better understand recovery perceptions over time and mitigate bias proxy-reporting, ultimately enhancing both patient care and outcomes research in geriatric orthopedic trauma patients.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112163"},"PeriodicalIF":2.2,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants for successful medullary fixation of the superior ramus
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-16 DOI: 10.1016/j.injury.2025.112170
Carol Lee , Justin Tilan , Brock D Foster , Eric White , John Garlich , Geoffrey S. Marecek

Objectives

The purpose of this study is to determine what demographic and anatomical variables affect successful placement of a superior medullary ramus screw, and how they affect the maximal diameter of that screw.

Methods

Design: Prognostic Level IV

Setting

Level I Trauma Center Patients/Participants: Two hundred consecutive patients underwent computed tomography (CT) of the pelvis. We included those patients aged 18 and older without osseous injury or abnormalities precluding measurement.

Intervention

3D reconstructions of the pelvis were created, and a virtual 3.5 mm cylindrical implant was placed from the pubic tubercle to the lateral cortex of the ilium. Success was defined as a bicortical virtual screw path from the ramus to the lateral ilium without cortical perforation. The cylinder was then expanded to model varying screw diameters. We then repeated this same process for unicortical retrograde screw insertion ending medial to the acetabular joint. Main Outcome Measures: Successful screw placement and maximum screw diameter.

Results

A 3.5 mm screw was successfully placed in 187 patients (93.5 %). One male (1/107, 0.9 %) and 12 females (12/93, 12.9 %) could not accommodate a 3.5 mm screw. All cases of perforation occurred lateral to the obturator foramen. Increasing height was associated with success, and male gender was associated with the ability to accommodate screws with a diameter 6.5 mm and larger.

Conclusions

Most patients can accommodate a 3.5 mm screw from the pubic tubercle to the ilium. Height and gender should be noted when planning medullary ramus fixation.
{"title":"Determinants for successful medullary fixation of the superior ramus","authors":"Carol Lee ,&nbsp;Justin Tilan ,&nbsp;Brock D Foster ,&nbsp;Eric White ,&nbsp;John Garlich ,&nbsp;Geoffrey S. Marecek","doi":"10.1016/j.injury.2025.112170","DOIUrl":"10.1016/j.injury.2025.112170","url":null,"abstract":"<div><h3>Objectives</h3><div>The purpose of this study is to determine what demographic and anatomical variables affect successful placement of a superior medullary ramus screw, and how they affect the maximal diameter of that screw.</div></div><div><h3>Methods</h3><div>Design: Prognostic Level IV</div></div><div><h3>Setting</h3><div>Level I Trauma Center Patients/Participants: Two hundred consecutive patients underwent computed tomography (CT) of the pelvis. We included those patients aged 18 and older without osseous injury or abnormalities precluding measurement.</div></div><div><h3>Intervention</h3><div>3D reconstructions of the pelvis were created, and a virtual 3.5 mm cylindrical implant was placed from the pubic tubercle to the lateral cortex of the ilium. Success was defined as a bicortical virtual screw path from the ramus to the lateral ilium without cortical perforation. The cylinder was then expanded to model varying screw diameters. We then repeated this same process for unicortical retrograde screw insertion ending medial to the acetabular joint. Main Outcome Measures: Successful screw placement and maximum screw diameter.</div></div><div><h3>Results</h3><div>A 3.5 mm screw was successfully placed in 187 patients (93.5 %). One male (1/107, 0.9 %) and 12 females (12/93, 12.9 %) could not accommodate a 3.5 mm screw. All cases of perforation occurred lateral to the obturator foramen. Increasing height was associated with success, and male gender was associated with the ability to accommodate screws with a diameter 6.5 mm and larger.</div></div><div><h3>Conclusions</h3><div>Most patients can accommodate a 3.5 mm screw from the pubic tubercle to the ilium. Height and gender should be noted when planning medullary ramus fixation.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112170"},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic hip dislocations associated with acute aortic injuries: A relevant injury complex
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-16 DOI: 10.1016/j.injury.2025.112172
Christian G Falgons , Connor C Park , Milton Lee (Chip) Routt Jr. , Ryan D DeAngelis , Stephen J Warner

Objectives

The primary aim of this study was to determine if an association exists between traumatic posterior hip dislocations and aortic injuries. Secondarily, this study assessed the incidence of chest imaging in patients with hip dislocations.

Methods

Design: Retrospective Review of a Consecutive Case Series. Setting: Academic level I trauma centre. Patient Selection Criteria: Fifteen-thousand-four-hundred-thirteen consecutive traumatically injured patients with at least one orthopaedic injury were initially identified. After excluding patients without a posterior hip dislocation after blunt trauma, seven-hundred-nine patients were included. Outcome Measurements and Comparisons: The primary outcome was the coincidence of blunt traumatic aortic injury with acute posterior dislocation of a native hip. The secondary outcome was the rates of chest imaging to screen for blunt aortic injuries in patients with posterior hip dislocations.

Results

The incidence of aortic injury with blunt trauma was 5.1 % in patients with a posterior hip dislocation and 1.6 % in patients without a posterior hip dislocation (OR = 3.3, CI: [2.3: 4.7], p < 0.001). Of the seven-hundred-nine patients with posterior hip dislocation, six hundred fifty-nine (93 %) received chest imaging as part of their initial workup, while thirty-four (4.8 %) never received chest imaging during hospitalization.

Conclusions

Despite improvements in automobile safety, this injury complex remains highly relevant. The findings advocate for routine chest imaging as part of the diagnostic trauma workup for patients with a native posterior hip dislocation.
{"title":"Traumatic hip dislocations associated with acute aortic injuries: A relevant injury complex","authors":"Christian G Falgons ,&nbsp;Connor C Park ,&nbsp;Milton Lee (Chip) Routt Jr. ,&nbsp;Ryan D DeAngelis ,&nbsp;Stephen J Warner","doi":"10.1016/j.injury.2025.112172","DOIUrl":"10.1016/j.injury.2025.112172","url":null,"abstract":"<div><h3>Objectives</h3><div>The primary aim of this study was to determine if an association exists between traumatic posterior hip dislocations and aortic injuries. Secondarily, this study assessed the incidence of chest imaging in patients with hip dislocations.</div></div><div><h3>Methods</h3><div><strong><em>Design:</em></strong> Retrospective Review of a Consecutive Case Series. <strong><em>Setting:</em></strong> Academic level I trauma centre. <strong><em>Patient Selection Criteria:</em></strong> Fifteen-thousand-four-hundred-thirteen consecutive traumatically injured patients with at least one orthopaedic injury were initially identified. After excluding patients without a posterior hip dislocation after blunt trauma, seven-hundred-nine patients were included. <strong><em>Outcome Measurements and Comparisons:</em></strong> The primary outcome was the coincidence of blunt traumatic aortic injury with acute posterior dislocation of a native hip. The secondary outcome was the rates of chest imaging to screen for blunt aortic injuries in patients with posterior hip dislocations.</div></div><div><h3>Results</h3><div>The incidence of aortic injury with blunt trauma was 5.1 % in patients with a posterior hip dislocation and 1.6 % in patients without a posterior hip dislocation (OR = 3.3, CI: [2.3: 4.7], <em>p</em> &lt; 0.001). Of the seven-hundred-nine patients with posterior hip dislocation, six hundred fifty-nine (93 %) received chest imaging as part of their initial workup, while thirty-four (4.8 %) never received chest imaging during hospitalization.</div></div><div><h3>Conclusions</h3><div>Despite improvements in automobile safety, this injury complex remains highly relevant. The findings advocate for routine chest imaging as part of the diagnostic trauma workup for patients with a native posterior hip dislocation.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112172"},"PeriodicalIF":2.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the intersection of AI and orthopaedic trauma research: Promise, pitfalls, and the path forward 人工智能和骨科创伤研究的交叉导航:希望、陷阱和前进的道路。
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-01 DOI: 10.1016/j.injury.2024.112085
Christopher G. Hendrix , Sean Young , Stephen D. Forro , Brent L. Norris
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引用次数: 0
Optimizing patient selection for ECMO after pediatric hypothermic cardiac arrest 优化小儿低体温心脏骤停后 ECMO 患者的选择。
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-01 DOI: 10.1016/j.injury.2024.111731
Jack H. Scaife , Hilary A. Hewes , Stephanie E. Iantorno , Christopher E. Clinker , Stephen J. Fenton , David E. Skarda , Zachary J. Kastenberg , Robert A. Swendiman , Katie W. Russell

Background

In 2004, our level 1 regional pediatric trauma center created a protocol to activate ECMO for children with suspected hypothermic cardiac arrest based on inclusion criteria: serum potassium ≤9, submersion <90 min, and core body temperature <30 °C. In 2017, Pasquier et al. developed a model to help predict the survival of adults after hypothermic cardiac arrest (HOPE score) that has not been validated in children. We sought to apply this score to our pediatric patient population to determine if it can optimize our patient selection.

Methods

This was a retrospective review of all patients cannulated onto VA ECMO for hypothermic cardiac arrest between 2004 and 2022. We used abstracted data points to calculate the HOPE score for our patient population, both with and without presumed asphyxia.

Results

Over 19 years, 18 patients were cannulated for suspected hypothermic arrest, with three survivors (17 %). The HOPE score survival prediction ranged from 1 to 86 % with presumed asphyxia and 6–98 % without presumed asphyxia. Survivor HOPE scores ranged from 9 to 86 % with presumed asphyxia and 42–98 % without presumed asphyxia. Non-survivors’ scores ranged 1–29 % with asphyxia and 6–57 % without asphyxia. A cutoff of >5 % predicted survival with asphyxia for ECMO could have decreased our cannulations by half without missing survivors.

Conclusion

ECMO can be a lifesaving measure for specific children after hypothermic arrest. However, identifying the patients that will benefit from this resource-intensive intervention remains difficult. HOPE score utilization may decrease the rate of futile cannulation in children, but multi-centered research is needed in the pediatric population.
背景:2004 年,我们地区一级儿科创伤中心制定了一项协议,根据纳入标准(血清钾≤9,浸没方法)为疑似低体温心脏骤停的儿童启动 ECMO:这是对 2004 年至 2022 年期间因体温过低心脏骤停而插管至 VA ECMO 的所有患者的回顾性研究。我们使用摘录的数据点来计算患者群体的 HOPE 评分,包括假定窒息和未假定窒息的患者:结果:19 年间,18 名患者因疑似低体温骤停而插管,其中 3 人存活(17%)。根据 HOPE 评分预测的存活率,推测窒息患者的存活率为 1% 至 86%,未推测窒息患者的存活率为 6% 至 98%。幸存者的 HOPE 分数在 9% 到 86% 之间,其中有假定窒息,42% 到 98% 没有假定窒息。非幸存者的得分范围为 1-29% 有窒息,6-57% 无窒息。如果 ECMO 的预测存活率大于 5%,我们的插管量就会减少一半,而不会漏掉存活者:结论:对于低体温骤停后的特定儿童来说,ECMO 是一项挽救生命的措施。结论:ECMO 可以挽救低体温骤停后特定儿童的生命。然而,确定哪些患者将从这种资源密集型干预中获益仍然很困难。使用 HOPE 评分可降低儿童的无用插管率,但需要在儿童群体中开展多中心研究。
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引用次数: 0
Lived experiences of working-age polytrauma patients in Germany - A qualitative Analysis 德国工作年龄段多发性创伤患者的生活经历--定性分析。
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-01 DOI: 10.1016/j.injury.2024.111938
Anne Neubert , Sebastian Hempe , Carina Jaekel , Catharina Gaeth , Christopher Spering , Katharina Fetz , Joachim Windolf , Erwin Kollig , Dan Bieler , LeAf-Trauma-Group

Background

Survivors of a major trauma experience a range of difficulties in relation to the reduction in physical, psychosocial, and cognitive functions, which can result in a reduced health-related quality of life. This study aims to explore lived experiences of major trauma survivors in the German healthcare system.

Methods

Semi-structured exploratory interviews were performed with nine major trauma survivors (18–55 years; Injury Severity Score ≥16). For exploratory analyses, an artificial intelligence-based coding software was used. Further, results were clustered by using the International Classification of Functioning, Disability and Health framework (ICF).

Results

Communication was one of the major topics concerning amongst others diverting opinions between different healthcare disciplines and a general lack of information. The participants showed a high demand for a contact person. Furthermore, social support was essential during recovery for those interviewed. Social network was not only important as emotional and physical support but also for overcoming of gaps in the healthcare system. The support by employers and colleagues seemed to be beneficial for our participants in relation to returning to work. Further, psychological consequences of trauma, and that mobility is a key factor for quality of life, self-efficacy and return to work were discussed.

Discussion

The qualitative analyses highlight several topics such as communication, burden of sickness, support systems that the participants mentioned as important along their journey through the German healthcare system during recovery. Through the ICF model the interplay of certain components that influenced the outcome of the major trauma survivors was visualized.

Implications

These results might offer a deepened understanding of modifiable components of a patient pathway in recovery process such as improvements of patient communication, provision of a contact person and others.
背景:重大创伤幸存者在身体、社会心理和认知功能下降方面会遇到一系列困难,从而导致与健康相关的生活质量下降。本研究旨在探讨德国医疗系统中重大创伤幸存者的生活经历:方法:对九名重大创伤幸存者(18-55 岁;受伤严重程度评分≥16 分)进行了半结构式探索性访谈。在探索性分析中,使用了基于人工智能的编码软件。此外,还使用国际功能、残疾和健康分类框架(ICF)对结果进行了分组:结果:交流是主要议题之一,涉及不同医疗学科之间的意见分歧和信息的普遍缺乏。参与者对联系人的需求很高。此外,社会支持对受访者的康复至关重要。社会网络不仅是情感和身体上的支持,而且对于克服医疗系统的不足也很重要。雇主和同事的支持似乎对受访者重返工作岗位很有帮助。此外,我们还讨论了创伤的心理后果,以及流动性是生活质量、自我效能感和重返工作岗位的关键因素:定性分析突出了几个主题,如沟通、疾病负担、支持系统,这些都是参与者在康复过程中通过德国医疗系统所提到的重要问题。通过 ICF 模型,可以直观地看出影响重大创伤幸存者康复结果的某些因素之间的相互作用:这些结果可能会加深人们对患者康复过程中可改变的因素的理解,如改善患者沟通、提供联系人等。
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引用次数: 0
Accuracy of the Norwegian trauma protocol. An observational population study from South-Western Norway 挪威创伤治疗方案的准确性。一项来自挪威西南部的观察性人口研究。
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-01-01 DOI: 10.1016/j.injury.2024.112063
Guro Bjørke , Ingvild Dalen , Kenneth Thorsen

Background

The Norwegian trauma plan was established in 2007 and renewed in 2017 defining national trauma team activation (TTA) criteria. Norwegian studies validating the performance of previous TTA protocols have found overtriage and undertriage to be out of line with the quality indicators set in the national trauma plan, but studies have not yet been published validating the new TTA protocol.

Material and method

This was a registry study of a prospectively maintained database in the period from 01/01/2018 to 12/31/2020. Data were collected from the Trauma Registry including prehospital documents. A total of 1519 patients were eligible, of which 95 were excluded, yielding a study population of 1424 patients. All patients were evaluated for a total of 29 criteria in four criteria groups: 1 Physiology, 2 Anatomical injury, 3 Mechanism of injury, and 4 Special considerations. Overtriage, undertriage, sensitivity and positive predictive value (PPV) were estimated for the current and alternative TTA protocols, criteria groups, and single criteria.

Results

The current Norwegian TTA protocol involving criteria groups 1–3 had a total sensitivity of 84.8 %, hence an undertriage of 15.2 % (95 % confidence interval, 11.1–20.3 %), and PPV of 19.2 % hence an overtriage of 80.8 % (78.3–83.1 %). Patients 60 years and older had an undertriage of 21.6 %, whilst patients under 60 years of age had an undertriage of 11.2 %. A TTA protocol including criteria group 4 as well yielded a lower undertriage (5.6 %) without significantly increasing overtriage (81.7 %), and a TTA protocol with criteria group 4 replacing group 3 yielded an undertriage of 7.4 % and an overtriage of 81.0 %. Criteria group 3 Mechanism of injury was the criteria group with the most overtriage, at 95 %. Patients that did not meet any criteria had a similar overtriage of 94 %.

Conclusion

Both overtriage and undertriage are out of line with the goals set in the Norwegian trauma plan. Undertriage is often caused by older patients that do not fulfill the trauma criteria in the current TTA protocol. Mechanism of injury increases overtriage but does not reduce undertriage. The TTA protocol could be improved by changing the composition of criteria groups, removal of single criteria with low PPV, and by better compliance to the existing criteria.
背景:挪威创伤计划于2007年建立,并于2017年更新,确定了国家创伤小组激活(TTA)标准。挪威的研究证实了以前的诊断辅助治疗方案的表现,发现过度分类和分类不足不符合国家创伤计划中设定的质量指标,但尚未发表的研究证实了新的诊断辅助治疗方案。材料和方法:本研究是对2018年1月1日至2020年12月31日期间前瞻性维护的数据库进行注册研究。数据收集自创伤登记处,包括院前文件。共有1519例患者符合条件,其中95例被排除,研究人群为1424例患者。所有患者分为4个标准组,共29项标准进行评估:1生理,2解剖损伤,3损伤机制,4特殊考虑。评估了当前和备选TTA方案、标准组和单一标准的过度分类、分类不足、敏感性和阳性预测值(PPV)。结果:目前挪威TTA方案涉及标准组1-3,总敏感性为84.8%,因此分类不足为15.2%(95%置信区间,11.1- 20.3%),PPV为19.2%,因此分类过度为80.8%(78.3- 83.1%)。60岁及以上患者的分类不足率为21.6%,而60岁以下患者的分类不足率为11.2%。包括第4组标准的TTA方案也产生了较低的分类不足(5.6%),但没有显著增加过度分类(81.7%),而用第4组标准取代第3组的TTA方案产生了7.4%的分类不足和81.0%的过度分类。损伤机制是过度分类最多的标准组,占95%。不符合任何标准的患者有类似的94%的过度分类。结论:分诊过多和分诊不足均不符合挪威创伤计划的目标。分类不足通常是由于老年患者不符合当前TTA协议中的创伤标准。损伤机制增加了过度分类,但不减少分类不足。可以通过改变标准组的组成、删除PPV低的单一标准以及更好地遵守现有标准来改进TTA协议。
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引用次数: 0
期刊
Injury-International Journal of the Care of the Injured
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