首页 > 最新文献

Clinical Neuropsychologist最新文献

英文 中文
A neuropsychological profile for high-grade primary central nervous system neuroendocrine tumor (CNS NET): a single-case study. 高级别原发性中枢神经系统神经内分泌肿瘤(CNS NET)的神经心理学特征:单例研究。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-22 DOI: 10.1080/13854046.2024.2356281
Stephanie N Steinberg, Kelsey C Hewitt, Cady K Block

Objective: Neuroendocrine tumors (NETs) are neoplasms that primarily occur in the lungs, appendix, small intestine, pancreas, and rectum, and typically metastasize to the liver or lymph nodes. However, in rare cases NETs can originate in the central nervous system (CNS). Understanding primary CNS NET neuropsychological manifestations aids in recommendations for neurocognitive follow-up, treatment and lifestyle planning, and future research. Method: Given the dearth of neuropsychological research for CNS NETs, we present a case seen in a 43-year-old woman. Results: Initial and 8-month follow-up neuropsychological evaluations of the patient revealed a Major Neurocognitive Disorder where the pattern of findings was consistent with tumor location and additional treatment-related factors. Reliable change indices at her re-evaluation revealed declines in verbal and visual memory, with statistical, yet not clinical, improvements in different domains. Follow-up monitoring of comprehensive care continued to occur after neuropsychological evaluations. Conclusions: This case study assists in the characterization of initial and follow-up neuropsychological presentation of a primary CNS NET, where evaluations helped inform clinical care and functional recommendations. This case demonstrates the importance for neuropsychologists to have awareness of various conditions, even rare conditions, which can inform a systematic approach to research and clinical care with neuro-oncological populations.

目的:神经内分泌肿瘤(NET神经内分泌肿瘤(NET)是主要发生在肺、阑尾、小肠、胰腺和直肠的肿瘤,通常会转移到肝脏或淋巴结。不过,在极少数情况下,NET 也可能起源于中枢神经系统(CNS)。了解原发性中枢神经系统 NET 的神经心理学表现有助于为神经认知随访、治疗和生活方式规划以及未来研究提供建议。方法:鉴于对中枢神经系统 NET 神经心理学研究的缺乏,我们介绍了一例 43 岁女性的病例。研究结果对患者进行的初次和 8 个月的随访神经心理学评估显示,患者存在严重的神经认知障碍,其发现模式与肿瘤位置和其他治疗相关因素一致。在对她进行再次评估时,可靠的变化指数显示她的言语和视觉记忆能力有所下降,不同领域的数据均有所改善,但没有临床改善。神经心理评估后,继续对综合护理进行后续监测。结论:本病例研究有助于描述原发性中枢神经系统母细胞瘤的初始和随访神经心理学表现,评估结果有助于为临床治疗和功能建议提供依据。本病例表明,神经心理学家对各种疾病,甚至是罕见疾病的认识非常重要,这可以为神经肿瘤人群的研究和临床治疗提供系统的方法。
{"title":"A neuropsychological profile for high-grade primary central nervous system neuroendocrine tumor (CNS NET): a single-case study.","authors":"Stephanie N Steinberg, Kelsey C Hewitt, Cady K Block","doi":"10.1080/13854046.2024.2356281","DOIUrl":"https://doi.org/10.1080/13854046.2024.2356281","url":null,"abstract":"<p><p><b>Objective:</b> Neuroendocrine tumors (NETs) are neoplasms that primarily occur in the lungs, appendix, small intestine, pancreas, and rectum, and typically metastasize to the liver or lymph nodes. However, in rare cases NETs can originate in the central nervous system (CNS). Understanding primary CNS NET neuropsychological manifestations aids in recommendations for neurocognitive follow-up, treatment and lifestyle planning, and future research. <b>Method:</b> Given the dearth of neuropsychological research for CNS NETs, we present a case seen in a 43-year-old woman. <b>Results:</b> Initial and 8-month follow-up neuropsychological evaluations of the patient revealed a Major Neurocognitive Disorder where the pattern of findings was consistent with tumor location and additional treatment-related factors. Reliable change indices at her re-evaluation revealed declines in verbal and visual memory, with statistical, yet not clinical, improvements in different domains. Follow-up monitoring of comprehensive care continued to occur after neuropsychological evaluations. <b>Conclusions:</b> This case study assists in the characterization of initial and follow-up neuropsychological presentation of a primary CNS NET, where evaluations helped inform clinical care and functional recommendations. This case demonstrates the importance for neuropsychologists to have awareness of various conditions, even rare conditions, which can inform a systematic approach to research and clinical care with neuro-oncological populations.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-15"},"PeriodicalIF":3.9,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerized assessment of executive functioning: Validation of the CNS Vital Signs executive functioning scores in a sample of community-dwelling older adults. 执行功能计算机化评估:在社区老年人样本中验证 CNS 生命体征执行功能评分。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-19 DOI: 10.1080/13854046.2024.2354953
Libby A DesRuisseaux, Michelle Gereau Mora, Yana Suchy

Objective: Computerized assessment of cognitive functioning has gained significant popularity over recent years, yet options for clinical assessment of executive functioning (EF) are lacking. One computerized testing platform, CNS Vital Signs (CNS-VS), offers tests designed to measure EF but requires further validation. The goal of the present study was to validate CNS-VS executive scores against standard clinical measures of EF. We also sought to determine whether a modified CNS-VS composite score that included variables purported to measure inhibition, switching, and working memory would outperform the currently available CNS-VS Executive Function Index. Method: A sample of 73 cognitively healthy older adults completed four tests from the Delis-Kaplan Executive Function System, the Digit Span subtest from the Wechsler Adult Intelligence Scale-fourth edition, and three CNS-VS tasks purported to measure inhibition, switching, and working memory. Results: Performances on the CNS-VS tests were predicted by performances on standard paper-and-pencil measures. Although the currently available CNS-VS Executive Function Index predicted unique variance in a well-validated paper-and-pencil EF composite score, our Modified CNS-VS EF composite accounted for unique variance above and beyond the original CNS-VS Executive Function Index, while the reverse was not true. Conclusions: The present results support the construct validity of CNS-VS EF tests but also suggest that modifications to their current composite scores would improve the prediction of EF performance.

目的:近年来,认知功能的计算机化评估大受欢迎,但执行功能(EF)的临床评估却缺乏选择。中枢神经系统生命体征(CNS-VS)是一种计算机化测试平台,可提供旨在测量执行功能的测试,但还需要进一步验证。本研究的目的是根据标准的临床 EF 测量方法对 CNS-VS 执行力评分进行验证。此外,我们还试图确定包含了据称可测量抑制、转换和工作记忆等变量的改良版 CNS-VS 综合评分是否会优于目前可用的 CNS-VS 执行功能指数。研究方法73 名认知健康的老年人完成了 Delis-Kaplan 执行功能系统中的四项测试、韦氏成人智力量表第四版中的数字跨度子测试,以及三项 CNS-VS 任务,这些任务旨在测量抑制、转换和工作记忆。测试结果CNS-VS测试的成绩可以通过标准纸笔测验的成绩来预测。虽然目前可用的 CNS-VS 执行功能指数可以预测经过验证的纸笔式 EF 综合得分的独特差异,但我们的 "修正 CNS-VS EF 综合得分 "所占的独特差异超过了原始的 CNS-VS 执行功能指数,而反之则不然。结论本研究结果支持 CNS-VS EF 测试的建构效度,但同时也表明,对其当前的综合评分进行修改可提高对 EF 表现的预测能力。
{"title":"Computerized assessment of executive functioning: Validation of the CNS Vital Signs executive functioning scores in a sample of community-dwelling older adults.","authors":"Libby A DesRuisseaux, Michelle Gereau Mora, Yana Suchy","doi":"10.1080/13854046.2024.2354953","DOIUrl":"https://doi.org/10.1080/13854046.2024.2354953","url":null,"abstract":"<p><p><b>Objective:</b> Computerized assessment of cognitive functioning has gained significant popularity over recent years, yet options for clinical assessment of executive functioning (EF) are lacking. One computerized testing platform, CNS Vital Signs (CNS-VS), offers tests designed to measure EF but requires further validation. The goal of the present study was to validate CNS-VS executive scores against standard clinical measures of EF. We also sought to determine whether a modified CNS-VS composite score that included variables purported to measure inhibition, switching, and working memory would outperform the currently available CNS-VS Executive Function Index. <b>Method:</b> A sample of 73 cognitively healthy older adults completed four tests from the Delis-Kaplan Executive Function System, the Digit Span subtest from the Wechsler Adult Intelligence Scale-fourth edition, and three CNS-VS tasks purported to measure inhibition, switching, and working memory. <b>Results:</b> Performances on the CNS-VS tests were predicted by performances on standard paper-and-pencil measures. Although the currently available CNS-VS Executive Function Index predicted unique variance in a well-validated paper-and-pencil EF composite score, our Modified CNS-VS EF composite accounted for unique variance above and beyond the original CNS-VS Executive Function Index, while the reverse was not true. <b>Conclusions:</b> The present results support the construct validity of CNS-VS EF tests but also suggest that modifications to their current composite scores would improve the prediction of EF performance.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-23"},"PeriodicalIF":3.9,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis coding of neurocognitive disorders. 神经认知障碍的诊断编码。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-19 DOI: 10.1080/13854046.2024.2345925
Suzan Uysal

Objective: Diagnosis coding is a core clinical competency. A basic understanding of the structure of the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM), the conventions and rules for diagnosis coding, and what constitutes accurate coding, is fundamental to the clinician's knowledge base. This commentary seeks to provide a practical framework for clinicians to perform accurate diagnosis coding of neurocognitive disorders. Method: This paper: (1) summarizes the structure of the ICD-10-CM, (2) describes the rules and conventions of diagnosis coding for diagnostic categories relevant to neurocognitive disorders, (3) presents clinical examples and pragmatic recommendations to help readers improve their day-to-day use of diagnosis codes, and (4) describes limitations and discrepancies in the diagnosis coding advice for neurocognitive disorders presented within the Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) and the DSM-5-TR Neurocognitive Disorders Supplement. Its content originates from the ICD-10-CM itself and its companion document, the ICD-10-CM Official Guidelines for Coding and Reporting. Conclusion: The ICD-10-CM classification scheme is logically organized and easy to navigate for users who understand its structure and rules. Many neuropsychologists rely on the DSM-5-TR diagnosis coding advice, however that advice is limited with respect to the range of diagnosis codes relevant to neurocognitive disorders and their underlying causes. Relying on the ICD-10-CM directly for diagnosis coding of neurocognitive disorders, rather than the DSM-5-TR or other secondary sources, is therefore preferable and aids clinicians in accurate diagnosis coding.

目的:诊断编码是一项核心临床能力。对《国际疾病分类》第十版临床修订版(ICD-10-CM)的结构、诊断编码的惯例和规则以及准确编码的构成要素的基本了解是临床医生知识库的基础。本评论旨在为临床医生提供一个实用的框架,以便对神经认知障碍进行准确的诊断编码。方法:本文(1)概述了 ICD-10-CM 的结构;(2)描述了与神经认知障碍相关的诊断类别的诊断编码规则和惯例;(3)提供了临床实例和实用建议,以帮助读者改进诊断编码的日常使用;(4)描述了《精神疾病诊断与统计手册》第五版文本修订版(DSM-5-TR)和《DSM-5-TR 神经认知障碍补充》中提出的神经认知障碍诊断编码建议的局限性和差异。其内容源自 ICD-10-CM 本身及其配套文件《ICD-10-CM 官方编码和报告指南》。结论对于了解其结构和规则的用户来说,ICD-10-CM 的分类方案组织合理,易于浏览。许多神经心理学家依赖于 DSM-5-TR 诊断编码建议,然而,该建议在与神经认知障碍及其根本原因相关的诊断编码范围方面是有限的。因此,直接依赖 ICD-10-CM 对神经认知障碍进行诊断编码,而不是依赖 DSM-5-TR 或其他次要来源是可取的,有助于临床医生进行准确的诊断编码。
{"title":"Diagnosis coding of neurocognitive disorders.","authors":"Suzan Uysal","doi":"10.1080/13854046.2024.2345925","DOIUrl":"https://doi.org/10.1080/13854046.2024.2345925","url":null,"abstract":"<p><p><b>Objective</b>: Diagnosis coding is a core clinical competency. A basic understanding of the structure of the <i>International Classification of Diseases, 10th Revision, Clinical Modification</i> (ICD-10-CM), the conventions and rules for diagnosis coding, and what constitutes accurate coding, is fundamental to the clinician's knowledge base. This commentary seeks to provide a practical framework for clinicians to perform accurate diagnosis coding of neurocognitive disorders. <b>Method</b>: This paper: (1) summarizes the structure of the ICD-10-CM, (2) describes the rules and conventions of diagnosis coding for diagnostic categories relevant to neurocognitive disorders, (3) presents clinical examples and pragmatic recommendations to help readers improve their day-to-day use of diagnosis codes, and (4) describes limitations and discrepancies in the diagnosis coding advice for neurocognitive disorders presented within the <i>Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition, Text Revision</i> (DSM-5-TR) and the <i>DSM-5-TR Neurocognitive Disorders Supplement</i>. Its content originates from the ICD-10-CM itself and its companion document, the <i>ICD-10-CM Official Guidelines for Coding and Reporting</i>. <b>Conclusion</b>: The ICD-10-CM classification scheme is logically organized and easy to navigate for users who understand its structure and rules. Many neuropsychologists rely on the DSM-5-TR diagnosis coding advice, however that advice is limited with respect to the range of diagnosis codes relevant to neurocognitive disorders and their underlying causes. Relying on the ICD-10-CM directly for diagnosis coding of neurocognitive disorders, rather than the DSM-5-TR or other secondary sources, is therefore preferable and aids clinicians in accurate diagnosis coding.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-16"},"PeriodicalIF":3.9,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-language testing improves bilinguals' verbal scores. 双语测试提高了双语学生的口头表达能力。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-14 DOI: 10.1080/13854046.2024.2353409
Mercedes Fernandez, Maria Alejandra Chavez, Erika dlRM Cabrera Ranaldi, Samruddhi Ayachit, Melissa Friedman

Objective: Research demonstrates that college educated, English language dominant bilinguals underperform relative to English speaking monolinguals on tests of verbal ability. We investigated whether accepting responses in their two languages would reveal improved performance in bilinguals, and whether such improvement would be of sufficient magnitude to demonstrate the same performance level as monolinguals. Method: Participants were college students attending the same university. Spanish-English bilinguals were compared to English speaking monolinguals on the Bilingual Verbal Ability Tests (BVAT), which include Picture Vocabulary, Oral Vocabulary, and Verbal Analogies. Results: When given the opportunity to respond in Spanish to items failed in English, bilinguals obtained significantly higher scores on all three subtests, and their performance matched that of monolinguals on Oral Vocabulary and Verbal Analogies. Conclusion: An "either-language" scoring approach may enable optimal measurement of verbal abilities in bilinguals. We provide normative data for use in applying the either-language scoring approach on subtests of the BVAT. We discuss the findings in the context of clinical assessment.

研究目的研究表明,受过大学教育、以英语为主的双语者在言语能力测试中的表现低于英语单语者。我们研究了接受双语者用两种语言做出的回答是否会显示出双语者成绩的提高,以及这种提高的幅度是否足以显示出与单语者相同的成绩水平。研究方法参与者为就读于同一所大学的大学生。在双语言语能力测试(BVAT)(包括图片词汇、口语词汇和言语类比)中,将西班牙语-英语双语者与英语单语者进行比较。测试结果当双语者有机会用西班牙语回答用英语答不上来的题目时,他们在所有三项测试中的得分都明显高于单语者,而且他们在口语词汇和言语类比方面的表现也与单语者相当。结论任选一种语言 "的评分方法可以对双语者的言语能力进行最佳测量。我们提供了常模数据,用于将 "任选一种语言 "计分法应用于 BVAT 的子测试。我们将结合临床评估对研究结果进行讨论。
{"title":"Dual-language testing improves bilinguals' verbal scores.","authors":"Mercedes Fernandez, Maria Alejandra Chavez, Erika dlRM Cabrera Ranaldi, Samruddhi Ayachit, Melissa Friedman","doi":"10.1080/13854046.2024.2353409","DOIUrl":"https://doi.org/10.1080/13854046.2024.2353409","url":null,"abstract":"<p><p><b>Objective:</b> Research demonstrates that college educated, English language dominant bilinguals underperform relative to English speaking monolinguals on tests of verbal ability. We investigated whether accepting responses in their two languages would reveal improved performance in bilinguals, and whether such improvement would be of sufficient magnitude to demonstrate the same performance level as monolinguals. <b>Method:</b> Participants were college students attending the same university. Spanish-English bilinguals were compared to English speaking monolinguals on the Bilingual Verbal Ability Tests (BVAT), which include <i>Picture Vocabulary</i>, <i>Oral Vocabulary</i>, and <i>Verbal Analogies</i>. <b>Results:</b> When given the opportunity to respond in Spanish to items failed in English, bilinguals obtained significantly higher scores on all three subtests, and their performance matched that of monolinguals on <i>Oral Vocabulary</i> and <i>Verbal Analogies</i>. <b>Conclusion:</b> An \"either-language\" scoring approach may enable optimal measurement of verbal abilities in bilinguals. We provide normative data for use in applying the either-language scoring approach on subtests of the BVAT. We discuss the findings in the context of clinical assessment.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-12"},"PeriodicalIF":3.9,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of impairment in cognitive instrumental activities of daily living for sexual and gender minority adults with reported Parkinson's disease. 报告患有帕金森病的性少数群体和性别少数群体成年人日常生活认知工具性活动受损的风险。
IF 3 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-13 DOI: 10.1080/13854046.2024.2350096
Ece Bayram, Sarah J Banks

Objective: To investigate the risk of impairment in cognitive instrumental activities of daily living (IADL) for people with Parkinson's (PwP) identifying as sexual and/or gender minorities (SGM). Method: Data were obtained from Fox Insight, an online, longitudinal study with self/informant-report questionnaires from PwP and people without Parkinson's. Groups consisted of PwP without cognitive IADL impairment at baseline, identifying as (1) SGM with female sex assigned at birth (SGM-F, n = 75); (2) cisgender, heterosexual with female sex assigned at birth (CH-F, n = 2046); (3) SGM with male sex assigned at birth (SGM-M, n = 84); (4) cisgender, heterosexual with male sex assigned at birth (CH-M, n = 2056). Impairment in cognitive IADL was based on Penn Parkinson's Daily Activities Questionnaire-15 (PDAQ-15). Group differences for PDAQ-15 and impairment likelihood during follow-up were assessed with unadjusted models and adjusting for variables that differed between the groups. Results: SGM-F were the youngest at Parkinson's diagnosis; SGM-M had the lowest PDAQ-15 at baseline (p ≤ .014 for all). Scores declined more for males than females in unadjusted and adjusted models (p < .001 for both). In unadjusted models, SGM-M had a higher impairment risk than PwP identifying as cisgender and heterosexual (p ≤ .018). In adjusted models, females had a lower impairment risk than males (p < .001). Age, education, and discrimination level were significant moderators (p < .001 for all). Conclusions: SGM-M can be at a higher risk for impairment in cognitive IADL, associated with social determinants. Female sex assigned at birth may be associated with a lower level of impairment risk, although this advantage can disappear with social determinants.

目的调查帕金森病患者(PwP)中性取向和/或性别少数群体(SGM)认知工具性日常生活活动(IADL)受损的风险。研究方法数据来自 Fox Insight,这是一项在线纵向研究,对帕金森病患者和非帕金森病患者进行自我/信息报告问卷调查。各组包括基线时未出现认知能力 IADL 损伤的帕金森病患者,他们分别是:(1)出生时性别为女性的 SGM(SGM-F,n = 75);(2)出生时性别为女性的顺性别异性恋者(CH-F,n = 2046);(3)出生时性别为男性的 SGM(SGM-M,n = 84);(4)出生时性别为男性的顺性别异性恋者(CH-M,n = 2056)。认知能力 IADL 的受损情况基于宾大帕金森日常活动问卷-15(PDAQ-15)。通过未调整模型和调整组间差异的变量来评估随访期间 PDAQ-15 和损伤可能性的组间差异。结果显示帕金森病诊断时,SGM-F 年龄最小;SGM-M 的 PDAQ-15 基线最低(P 均≤ .014)。在未调整模型和调整模型中,男性的得分下降幅度大于女性(两者的 p 均小于 .001)。在未经调整的模型中,SGM-M 的损伤风险高于确认为顺性和异性恋的 PwP(p ≤ .018)。在调整后的模型中,女性受损风险低于男性(p < .001)。年龄、教育程度和歧视程度是重要的调节因素(所有因素的 p 均小于 .001)。结论SGM-M 在认知 IADL 方面受损的风险较高,这与社会决定因素有关。出生时被指定的女性性别可能与较低程度的损伤风险有关,尽管这种优势可能会随着社会决定因素的消失而消失。
{"title":"Risk of impairment in cognitive instrumental activities of daily living for sexual and gender minority adults with reported Parkinson's disease.","authors":"Ece Bayram, Sarah J Banks","doi":"10.1080/13854046.2024.2350096","DOIUrl":"10.1080/13854046.2024.2350096","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the risk of impairment in cognitive instrumental activities of daily living (IADL) for people with Parkinson's (PwP) identifying as sexual and/or gender minorities (SGM). <b>Method:</b> Data were obtained from Fox Insight, an online, longitudinal study with self/informant-report questionnaires from PwP and people without Parkinson's. Groups consisted of PwP without cognitive IADL impairment at baseline, identifying as (1) SGM with female sex assigned at birth (SGM-F, <i>n</i> = 75); (2) cisgender, heterosexual with female sex assigned at birth (CH-F, <i>n</i> = 2046); (3) SGM with male sex assigned at birth (SGM-M, <i>n</i> = 84); (4) cisgender, heterosexual with male sex assigned at birth (CH-M, <i>n</i> = 2056). Impairment in cognitive IADL was based on Penn Parkinson's Daily Activities Questionnaire-15 (PDAQ-15). Group differences for PDAQ-15 and impairment likelihood during follow-up were assessed with unadjusted models and adjusting for variables that differed between the groups. <b>Results:</b> SGM-F were the youngest at Parkinson's diagnosis; SGM-M had the lowest PDAQ-15 at baseline (<i>p</i> ≤ .014 for all). Scores declined more for males than females in unadjusted and adjusted models (<i>p</i> < .001 for both). In unadjusted models, SGM-M had a higher impairment risk than PwP identifying as cisgender and heterosexual (<i>p</i> ≤ .018). In adjusted models, females had a lower impairment risk than males (<i>p</i> < .001). Age, education, and discrimination level were significant moderators (<i>p</i> < .001 for all). <b>Conclusions:</b> SGM-M can be at a higher risk for impairment in cognitive IADL, associated with social determinants. Female sex assigned at birth may be associated with a lower level of impairment risk, although this advantage can disappear with social determinants.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-22"},"PeriodicalIF":3.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Walking time and genetic predisposition for Alzheimer's disease: Results from the HELIAD study. 步行时间与阿尔茨海默病的遗传倾向:HELIAD 研究的结果。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-13 DOI: 10.1080/13854046.2024.2344869
Stefanos N Sampatakakis, Niki Mourtzi, Sokratis Charisis, Eirini Mamalaki, Eva Ntanasi, Alex Hatzimanolis, Alfredo Ramirez, Jean-Charles Lambert, Mary Yannakoulia, Mary H Kosmidis, Efthimios Dardiotis, Georgios Hadjigeorgiou, Maria Megalou, Paraskevi Sakka, Nikolaos Scarmeas

Objective: Our study aimed to explore whether physical condition might affect the association between genetic predisposition for Alzheimer's Disease (AD) and AD incidence. Methods: The sample of participants consisted of 561 community-dwelling adults over 64 years old, without baseline dementia (508 cognitively normal and 53 with mild cognitive impairment), deriving from the HELIAD, an ongoing longitudinal study with follow-up evaluations every 3 years. Physical condition was assessed at baseline through walking time (WT), while a Polygenic Risk Score for late onset AD (PRS-AD) was used to estimate genetic predisposition. The association between WT and PRS-AD with AD incidence was evaluated with Cox proportional hazard models adjusted for age, sex, education years, global cognition score and APOE ε-4 genotype. Then, the association between WT and AD incidence was investigated after stratifying participants by low and high PRS-AD. Finally, we examined the association between PRS-AD and AD incidence after stratifying participants by WT. Results: Both WT and PRS-AD were connected with increased AD incidence (p < 0.05), after adjustments. In stratified analyses, in the slow WT group participants with a greater genetic risk had a 2.5-fold higher risk of developing AD compared to participants with lower genetic risk (p = 0.047). No association was observed in the fast WT group or when participants were stratified based on PRS-AD. Conclusions: Genetic predisposition for AD is more closely related to AD incidence in the group of older adults with slow WT. Hence, physical condition might be a modifier in the relationship of genetic predisposition with AD incidence.

研究目的我们的研究旨在探讨身体状况是否会影响阿尔茨海默病(AD)遗传易感性与 AD 发病率之间的关联。研究方法参与者样本包括 561 名 64 岁以上、无痴呆症基线的社区成年人(508 人认知正常,53 人有轻度认知障碍),他们来自 HELIAD,这是一项正在进行的纵向研究,每 3 年进行一次随访评估。通过步行时间(WT)对基线身体状况进行评估,同时使用晚发性老年痴呆症多基因风险评分(PRS-AD)来估计遗传易感性。WT和PRS-AD与AD发病率之间的关系采用Cox比例危险模型进行评估,并对年龄、性别、受教育年限、总体认知评分和APOE ε-4基因型进行了调整。然后,根据低PRS-AD和高PRS-AD对参与者进行分层后,研究了WT与AD发病率之间的关系。最后,我们根据 WT 对参与者进行分层后,研究了 PRS-AD 与注意力缺失症发病率之间的关系。结果显示WT和PRS-AD都与AD发病率增加有关(P = 0.047)。在快速 WT 组或根据 PRS-AD 对参与者进行分层后,均未观察到两者之间的关联。结论注意力缺失症的遗传易感性与慢速 WT 组老年人的注意力缺失症发病率关系更为密切。因此,在遗传易感性与AD发病率的关系中,身体状况可能是一个调节因素。
{"title":"Walking time and genetic predisposition for Alzheimer's disease: Results from the HELIAD study.","authors":"Stefanos N Sampatakakis, Niki Mourtzi, Sokratis Charisis, Eirini Mamalaki, Eva Ntanasi, Alex Hatzimanolis, Alfredo Ramirez, Jean-Charles Lambert, Mary Yannakoulia, Mary H Kosmidis, Efthimios Dardiotis, Georgios Hadjigeorgiou, Maria Megalou, Paraskevi Sakka, Nikolaos Scarmeas","doi":"10.1080/13854046.2024.2344869","DOIUrl":"https://doi.org/10.1080/13854046.2024.2344869","url":null,"abstract":"<p><p><b>Objective:</b> Our study aimed to explore whether physical condition might affect the association between genetic predisposition for Alzheimer's Disease (AD) and AD incidence. <b>Methods:</b> The sample of participants consisted of 561 community-dwelling adults over 64 years old, without baseline dementia (508 cognitively normal and 53 with mild cognitive impairment), deriving from the HELIAD, an ongoing longitudinal study with follow-up evaluations every 3 years. Physical condition was assessed at baseline through walking time (WT), while a Polygenic Risk Score for late onset AD (PRS-AD) was used to estimate genetic predisposition. The association between WT and PRS-AD with AD incidence was evaluated with Cox proportional hazard models adjusted for age, sex, education years, global cognition score and <i>APOE</i> ε-4 genotype. Then, the association between WT and AD incidence was investigated after stratifying participants by low and high PRS-AD. Finally, we examined the association between PRS-AD and AD incidence after stratifying participants by WT. <b>Results:</b> Both WT and PRS-AD were connected with increased AD incidence (<i>p</i> < 0.05), after adjustments. In stratified analyses, in the slow WT group participants with a greater genetic risk had a 2.5-fold higher risk of developing AD compared to participants with lower genetic risk (<i>p</i> = 0.047). No association was observed in the fast WT group or when participants were stratified based on PRS-AD. <b>Conclusions:</b> Genetic predisposition for AD is more closely related to AD incidence in the group of older adults with slow WT. Hence, physical condition might be a modifier in the relationship of genetic predisposition with AD incidence.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-17"},"PeriodicalIF":3.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introducing the North American Association of Practicum Sites in Neuropsychology (NAPSN): development of a new organization devoted to facilitating high quality practicum training. 介绍北美神经心理学实习基地协会(NAPSN):发展一个致力于促进高质量实习培训的新组织。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-13 DOI: 10.1080/13854046.2024.2353924
Douglas M Whiteside, Alissa M Butts, Erin Holker, Carly R Anderson, Christine Koterba, Suzanne Penna

Introduction: In February 2023, a work group began to develop a new North American organization in neuropsychology to represent and support practicum-training sites. While other training-focused organizations such as the Association of Postdoctoral Programs in Clinical Neuropsychology (APPCN) and the Association of Internship Training in Clinical Neuropsychology (AITCN) have existed for many years, no organization exists to promote and support practicum level training outside of doctoral degree programs. The work group developed such an organization, subsequently named the North American Association of Practicum Sites in Neuropsychology (NAPSN), beginning with a mission statement and general purpose of the organization. Methods: The work group divided members into five task forces focused on various tasks needed to start the organization, including Mission/Vision, Administrative Structure, Membership, Financials, and Bylaws. The entire work group met monthly with additional meetings and work via email for the various task forces, which resulted in the development of a mission statement and bylaws, as well as a framework for program administration, membership requirements and financial needs. Conclusions: The group developed NAPSN primarily as a resource to support diverse practicum programs in urban, suburban, and rural areas in the US and Canada to provide optimal graduate level clinical training in neuropsychology. Didactics aimed specifically at practicum students was one need identified early in the process. NAPSN is developing a website-based resource in collaboration with other training organizations to increase the didactic offerings to practicum students. Other initiatives and collaborative efforts will be undertaken over time as circumstances warrant.

导言:2023 年 2 月,一个工作小组开始筹建一个新的北美神经心理学组织,以代表和支持实习培训基地。虽然临床神经心理学博士后项目协会(APPCN)和临床神经心理学实习培训协会(AITCN)等其他以培训为重点的组织已经存在多年,但目前还没有一个组织来促进和支持博士学位项目之外的实习培训。工作小组建立了这样一个组织,随后将其命名为北美神经心理学实习基地协会(NAPSN),并首先制定了该组织的使命宣言和总体目标。工作方法:工作小组将成员分成五个工作组,分别负责组织成立所需的各项任务,包括使命/愿景、行政结构、成员资格、财务和章程。整个工作小组每月召开一次会议,各工作组还通过电子邮件召开额外会议和开展工作,最终制定了使命宣言和章程,以及计划管理、成员要求和财务需求框架。结论:NAPSN 主要是作为一种资源来支持美国和加拿大城市、郊区和农村地区的各种实习项目,以提供最佳的神经心理学研究生临床培训。在这一过程中,我们很早就发现了针对实习学生的教学需求。NAPSN 正在与其他培训机构合作开发基于网站的资源,以增加为实习学生提供的教学内容。随着时间的推移,还将根据实际情况采取其他措施和开展合作。
{"title":"Introducing the North American Association of Practicum Sites in Neuropsychology (NAPSN): development of a new organization devoted to facilitating high quality practicum training.","authors":"Douglas M Whiteside, Alissa M Butts, Erin Holker, Carly R Anderson, Christine Koterba, Suzanne Penna","doi":"10.1080/13854046.2024.2353924","DOIUrl":"https://doi.org/10.1080/13854046.2024.2353924","url":null,"abstract":"<p><p><b>Introduction:</b> In February 2023, a work group began to develop a new North American organization in neuropsychology to represent and support practicum-training sites. While other training-focused organizations such as the Association of Postdoctoral Programs in Clinical Neuropsychology (APPCN) and the Association of Internship Training in Clinical Neuropsychology (AITCN) have existed for many years, no organization exists to promote and support practicum level training outside of doctoral degree programs. The work group developed such an organization, subsequently named the North American Association of Practicum Sites in Neuropsychology (NAPSN), beginning with a mission statement and general purpose of the organization. <b>Methods:</b> The work group divided members into five task forces focused on various tasks needed to start the organization, including Mission/Vision, Administrative Structure, Membership, Financials, and Bylaws. The entire work group met monthly with additional meetings and work <i>via</i> email for the various task forces, which resulted in the development of a mission statement and bylaws, as well as a framework for program administration, membership requirements and financial needs. <b>Conclusions:</b> The group developed NAPSN primarily as a resource to support diverse practicum programs in urban, suburban, and rural areas in the US and Canada to provide optimal graduate level clinical training in neuropsychology. Didactics aimed specifically at practicum students was one need identified early in the process. NAPSN is developing a website-based resource in collaboration with other training organizations to increase the didactic offerings to practicum students. Other initiatives and collaborative efforts will be undertaken over time as circumstances warrant.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-11"},"PeriodicalIF":3.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140915724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive phenotypes in patients with relapsing-remitting multiple sclerosis with different disease duration, applying the international classification of cognitive disorders in MS (IC-CoDiMS). 应用多发性硬化症认知障碍国际分类法(IC-CoDiMS),研究不同病程的复发缓解型多发性硬化症患者的认知表型。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-07 DOI: 10.1080/13854046.2024.2348831
Cláudia Sousa, Teresa Jacques, Márcia França, Patrícia Campos, Maria José Sá, Rui A Alves

Objective: Cognitive impairment is experienced by 40-70% of multiple sclerosis patients, with information processing speed and memory most affected. Until now, cognitive results classified patients as impaired and not impaired. With this dichotomous approach, it is difficult to identify, in a heterogeneous group of patients with cognitive impairment, which cognitive domain(s) are most altered. This study aims to identify cognitive phenotypes in a clinical cohort of adult patients with Relapsing-Remitting Multiple Sclerosis (RRMS) using the International Classification of Cognitive Disorders in MS (IC-CoDiMS) and to characterize their clinical features. Methods: Three hundred patients with RRMS underwent neuropsychological assessment with the Brief Repeatable Battery of Neuropsychological Tests (BRBN-T) and the Brief International Cognitive Multiple Sclerosis (BICAMS). Results: In our cohort, the mean age was 41.38 [11.48 SD] years, and 205 [68.3%] were women. At the -1 SD threshold, 49% were cognitively intact, 25% had uni-domain impairment, 17% had bi-domain impairment, and 9% had multi-domain impairment. Processing speed was the most frequent single-domain impairment, followed by memory and verbal fluency. At the -1.5 SD threshold, 74.7% were cognitively intact, 17% had uni-domain impairment, 6% had bi-domain impairment, had bi-domain impairment, and 3.0% had multi-domain impairment. Memory was the most frequent single-domain impairment, followed by processing speed and verbal fluency. Conclusions: This study corroborates the importance of determining cognitive phenotypes through taxonomy (IC-CoDiMS). In addition, it contributes to improving the classification of cognitive phenotypes in patients with RRMS to enhance the development of more effective treatments and cognitive interventions.

目的:40%-70%的多发性硬化症患者会出现认知障碍,其中信息处理速度和记忆力受影响最大。迄今为止,认知结果将患者分为受损和未受损两类。采用这种二分法,很难在认知功能受损的异质性患者群体中确定哪个(些)认知领域变化最大。本研究旨在利用多发性硬化症认知障碍国际分类(IC-CoDiMS),在一组临床成年复发性多发性硬化症(RRMS)患者中识别认知表型,并描述其临床特征。研究方法300名RRMS患者接受了神经心理学评估,包括简易可重复神经心理学测试组合(BRBN-T)和简易国际认知多发性硬化症(BICAMS)。研究结果在我们的队列中,平均年龄为 41.38 [11.48 SD] 岁,女性为 205 [68.3%]。在-1 SD临界值时,49%的人认知功能完好,25%的人有单领域障碍,17%的人有双领域障碍,9%的人有多领域障碍。处理速度是最常见的单领域障碍,其次是记忆和语言流畅性。在-1.5 SD临界值时,74.7%的人认知功能完好,17%的人有单领域障碍,6%的人有双领域障碍,3.0%的人有多领域障碍。记忆力是最常见的单领域障碍,其次是处理速度和语言流畅性。结论这项研究证实了通过分类法(IC-CoDiMS)确定认知表型的重要性。此外,该研究还有助于改进 RRMS 患者认知表型的分类,从而促进更有效的治疗和认知干预措施的开发。
{"title":"Cognitive phenotypes in patients with relapsing-remitting multiple sclerosis with different disease duration, applying the international classification of cognitive disorders in MS (IC-CoDiMS).","authors":"Cláudia Sousa, Teresa Jacques, Márcia França, Patrícia Campos, Maria José Sá, Rui A Alves","doi":"10.1080/13854046.2024.2348831","DOIUrl":"https://doi.org/10.1080/13854046.2024.2348831","url":null,"abstract":"<p><p><b>Objective:</b> Cognitive impairment is experienced by 40-70% of multiple sclerosis patients, with information processing speed and memory most affected. Until now, cognitive results classified patients as impaired and not impaired. With this dichotomous approach, it is difficult to identify, in a heterogeneous group of patients with cognitive impairment, which cognitive domain(s) are most altered. This study aims to identify cognitive phenotypes in a clinical cohort of adult patients with Relapsing-Remitting Multiple Sclerosis (RRMS) using the International Classification of Cognitive Disorders in MS (IC-CoDiMS) and to characterize their clinical features. <b>Methods:</b> Three hundred patients with RRMS underwent neuropsychological assessment with the Brief Repeatable Battery of Neuropsychological Tests (BRBN-T) and the Brief International Cognitive Multiple Sclerosis (BICAMS). <b>Results:</b> In our cohort, the mean age was 41.38 [11.48 SD] years, and 205 [68.3%] were women. At the -1 SD threshold, 49% were cognitively intact, 25% had uni-domain impairment, 17% had bi-domain impairment, and 9% had multi-domain impairment. Processing speed was the most frequent single-domain impairment, followed by memory and verbal fluency. At the -1.5 SD threshold, 74.7% were cognitively intact, 17% had uni-domain impairment, 6% had bi-domain impairment, had bi-domain impairment, and 3.0% had multi-domain impairment. Memory was the most frequent single-domain impairment, followed by processing speed and verbal fluency. <b>Conclusions:</b> This study corroborates the importance of determining cognitive phenotypes through taxonomy (IC-CoDiMS). In addition, it contributes to improving the classification of cognitive phenotypes in patients with RRMS to enhance the development of more effective treatments and cognitive interventions.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1-19"},"PeriodicalIF":3.9,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic and/or multimodal assessments for social cognition in neuropsychology: Results from a systematic literature review. 神经心理学中社会认知的动态和/或多模式评估:来自系统文献综述的结果。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-10-30 DOI: 10.1080/13854046.2023.2266172
Eva-Flore Msika, Mathilde Despres, Pascale Piolino, Pauline Narme

Objective: Despite the prevalence of socio-cognitive disturbances, and their important diagnostic/therapeutic implications, the assessment of these disturbances remains scarce. This systematic review aims to identify available social cognition tools for adult assessment that use multimodal and/or dynamic social cues, specifying their strengths and limitations (e.g. from a methodological, psychometric, ecological, and clinical perspective). Method: An electronic search was conducted in Pubmed, PsychINFO, Embase and Scopus databases for articles published up to the 3th of January 2023 and the first 200 Google Scholar results on the same date. The PRISMA methodology was applied, 3884 studies were screened based on title and abstract and 329 full texts were screened. Articles using pseudo-dynamic methodologies (e.g. morphing), reported only subjective or self-reported measures, or investigated only physiological or brain activity responses were excluded. Results: In total, 149 works were included in this review, representing 65 assessment tools (i.e. 48% studying emotion recognition (n = 31), 32% Theory of Mind (n = 21), 5% empathy (n = 3), 1.5% moral cognition/social reasoning (n = 1), and 14% being multimodal (n = 9)). For each study, the tool's main characteristics, psychometric properties, ecological validity indicators and available norms are reported. The tools are presented according to social-cognitive process assessed and communication channels used. Conclusions: This study highlights the lack of validated and standardized tools. A few tools appear to partially meet some clinical needs. The development of methodologies using a first-person paradigm and taking into account the multidimensional nature of social cognition seems a relevant research endeavour for greater ecological validity.

目的:尽管社会认知障碍的普遍性及其重要的诊断/治疗意义,但对这些障碍的评估仍然很少。这项系统综述旨在确定可用于成人评估的社会认知工具,这些工具使用多模式和/或动态社会线索,明确其优势和局限性(例如,从方法论、心理测量学、生态学和临床角度)。方法:在Pubmed、PsychINFO、Embase和Scopus数据库中进行电子搜索,查找截至2023年1月3日发表的文章以及当天的前200个谷歌学者结果。应用PRISMA方法,根据标题和摘要筛选了3884项研究,筛选了329篇全文。排除了使用伪动态方法(如变形)、仅报告主观或自我报告测量或仅调查生理或大脑活动反应的文章。结果:共有149篇作品被纳入本综述,代表了65种评估工具(即48%的作品研究情绪识别(n = 31),32%心学(n = 21),5%的同理心(n = 3) ,1.5%的道德认知/社会推理(n = 1) ,14%为多峰(n = 9) )。每项研究都报告了该工具的主要特征、心理测量特性、生态有效性指标和可用规范。这些工具是根据评估的社会认知过程和使用的沟通渠道提出的。结论:本研究强调了缺乏经过验证和标准化的工具。一些工具似乎部分满足了一些临床需求。使用第一人称范式并考虑到社会认知的多维性的方法论的发展似乎是一项旨在提高生态有效性的相关研究努力。
{"title":"Dynamic and/or multimodal assessments for social cognition in neuropsychology: Results from a systematic literature review.","authors":"Eva-Flore Msika, Mathilde Despres, Pascale Piolino, Pauline Narme","doi":"10.1080/13854046.2023.2266172","DOIUrl":"10.1080/13854046.2023.2266172","url":null,"abstract":"<p><p><b>Objective:</b> Despite the prevalence of socio-cognitive disturbances, and their important diagnostic/therapeutic implications, the assessment of these disturbances remains scarce. This systematic review aims to identify available social cognition tools for adult assessment that use multimodal and/or dynamic social cues, specifying their strengths and limitations (e.g. from a methodological, psychometric, ecological, and clinical perspective). <b>Method:</b> An electronic search was conducted in Pubmed, PsychINFO, Embase and Scopus databases for articles published up to the 3<sup>th</sup> of January 2023 and the first 200 Google Scholar results on the same date. The PRISMA methodology was applied, 3884 studies were screened based on title and abstract and 329 full texts were screened. Articles using pseudo-dynamic methodologies (e.g. morphing), reported only subjective or self-reported measures, or investigated only physiological or brain activity responses were excluded. <b>Results:</b> In total, 149 works were included in this review, representing 65 assessment tools (i.e. 48% studying emotion recognition (<i>n</i> = 31), 32% Theory of Mind (<i>n</i> = 21), 5% empathy (<i>n</i> = 3), 1.5% moral cognition/social reasoning (<i>n</i> = 1), and 14% being multimodal (<i>n</i> = 9)). For each study, the tool's main characteristics, psychometric properties, ecological validity indicators and available norms are reported. The tools are presented according to social-cognitive process assessed and communication channels used. <b>Conclusions:</b> This study highlights the lack of validated and standardized tools. A few tools appear to partially meet some clinical needs. The development of methodologies using a first-person paradigm and taking into account the multidimensional nature of social cognition seems a relevant research endeavour for greater ecological validity.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"922-962"},"PeriodicalIF":3.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71415373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utility of the NIH Toolbox Cognition Battery in middle to older aged adults with longstanding type 1 diabetes: The DCCT/EDIC study. NIH工具箱认知电池在患有长期1型糖尿病的中老年人中的应用:DCCT/EDIC研究。
IF 3.9 3区 心理学 Q2 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-10-09 DOI: 10.1080/13854046.2023.2266876
Naomi S Chaytor, Victoria R Trapani, Barbara H Braffett, Luciana M Fonseca, Gayle M Lorenzi, Rose A Gubitosi-Klug, Susan Hitt, Kaleigh Farrell, Alan M Jacobson, Christopher M Ryan

Objective: Adults with type 1 diabetes (T1D) face an increased risk for cognitive decline and dementia. Diabetes-related and vascular risk factors have been linked to cognitive decline using detailed neuropsychological testing; however, it is unclear if cognitive screening batteries can detect cognitive changes associated with aging in T1D. Method: 1,049 participants with T1D (median age 59 years; range 43-74) from the Diabetes Control and Complications Trial (DCCT), and the follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) study, completed the NIH Toolbox Cognition Battery (NIHTB-C) and Montreal Cognitive Assessment (MoCA). Neuropsychological assessments, depression, glycated hemoglobin levels (HbA1c), severe hypoglycemia, T1D complications, and vascular risk factors were assessed repeatedly over 32 years to determine associations with current NIHTB-C performance. Available cognitive data was clinically adjudicated to determine cognitive impairment status. Results: NIHTB-C scores had moderate associations (r = 0.36-0.53) with concurrently administered neuropsychological tests. In multivariate models, prior severe hypoglycemic episodes, depression symptoms, nephropathy, lower BMI, and higher HbA1c and LDL cholesterol were associated with poorer NIHTB-C Fluid Cognition Composite scores. The NIHTB-C adequately detected adjudicated cognitive impairment (Area Under the Curve = 0.86; optimal cut score ≤90). The MoCA performed similarly (Area Under the Curve = 0.83; optimal cut score ≤25). Conclusions: The NIHTB-C is sensitive to the cognitive effects of diabetes-related and vascular risk factors, correlated with neuropsychological testing, and accurately detects adjudicated cognitive impairment. These data support its use as a screening test in middle to older aged adults with T1D to determine if referral for detailed neuropsychological assessment is needed.

目的:患有1型糖尿病(T1D)的成年人面临认知能力下降和痴呆的风险增加。通过详细的神经心理学测试,糖尿病相关和血管风险因素与认知能力下降有关;然而,目前尚不清楚认知筛查电池是否能检测到与T1D衰老相关的认知变化。方法:1049名T1D患者(中位年龄59岁) 年;范围43-74),以及糖尿病干预和并发症流行病学(EDIC)的后续研究,完成了NIH工具箱认知电池(NIHTB-C)和蒙特利尔认知评估(MoCA)。对神经心理学评估、抑郁、糖化血红蛋白水平(HbA1c)、严重低血糖、T1D并发症和血管危险因素进行了反复评估 年来确定与当前NIHTB-C表现的相关性。对可用的认知数据进行临床裁定,以确定认知障碍状态。结果:NIHTB-C评分具有中度相关性(r = 0.36-0.53),同时进行神经心理测试。在多变量模型中,既往严重低血糖发作、抑郁症状、肾病、较低的BMI、较高的HbA1c和LDL胆固醇与较差的NIHTB-C流体认知综合评分相关。NIHTB-C充分检测到判定的认知障碍(曲线下面积=0.86;最佳切割分数≤90)。MoCA的表现类似(曲线下面积=0.83;最佳切割分数≤25)。结论:NIHTB-C对糖尿病相关因素和血管危险因素的认知影响敏感,与神经心理测试相关,并能准确检测判定的认知障碍。这些数据支持将其用作中老年T1D患者的筛查测试,以确定是否需要转诊进行详细的神经心理评估。
{"title":"Utility of the NIH Toolbox Cognition Battery in middle to older aged adults with longstanding type 1 diabetes: The DCCT/EDIC study.","authors":"Naomi S Chaytor, Victoria R Trapani, Barbara H Braffett, Luciana M Fonseca, Gayle M Lorenzi, Rose A Gubitosi-Klug, Susan Hitt, Kaleigh Farrell, Alan M Jacobson, Christopher M Ryan","doi":"10.1080/13854046.2023.2266876","DOIUrl":"10.1080/13854046.2023.2266876","url":null,"abstract":"<p><p><b>Objective:</b> Adults with type 1 diabetes (T1D) face an increased risk for cognitive decline and dementia. Diabetes-related and vascular risk factors have been linked to cognitive decline using detailed neuropsychological testing; however, it is unclear if cognitive screening batteries can detect cognitive changes associated with aging in T1D. <b>Method:</b> 1,049 participants with T1D (median age 59 years; range 43-74) from the Diabetes Control and Complications Trial (DCCT), and the follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) study, completed the NIH Toolbox Cognition Battery (NIHTB-C) and Montreal Cognitive Assessment (MoCA). Neuropsychological assessments, depression, glycated hemoglobin levels (HbA1c), severe hypoglycemia, T1D complications, and vascular risk factors were assessed repeatedly over 32 years to determine associations with current NIHTB-C performance. Available cognitive data was clinically adjudicated to determine cognitive impairment status. <b>Results:</b> NIHTB-C scores had moderate associations (<i>r</i> = 0.36-0.53) with concurrently administered neuropsychological tests. In multivariate models, prior severe hypoglycemic episodes, depression symptoms, nephropathy, lower BMI, and higher HbA1c and LDL cholesterol were associated with poorer NIHTB-C Fluid Cognition Composite scores. The NIHTB-C adequately detected adjudicated cognitive impairment (Area Under the Curve = 0.86; optimal cut score ≤90). The MoCA performed similarly (Area Under the Curve = 0.83; optimal cut score ≤25). <b>Conclusions:</b> The NIHTB-C is sensitive to the cognitive effects of diabetes-related and vascular risk factors, correlated with neuropsychological testing, and accurately detects adjudicated cognitive impairment. These data support its use as a screening test in middle to older aged adults with T1D to determine if referral for detailed neuropsychological assessment is needed.</p>","PeriodicalId":55250,"journal":{"name":"Clinical Neuropsychologist","volume":" ","pages":"1007-1027"},"PeriodicalIF":3.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11001788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41184203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Clinical Neuropsychologist
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1