Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.026182
Qiaojing Jia, Yu V. Fu
{"title":"The microRNA pathway activation in insect cell model upon Autographa californica multiple nucleopolyhedrovirus infection","authors":"Qiaojing Jia, Yu V. Fu","doi":"10.32604/biocell.2023.026182","DOIUrl":"https://doi.org/10.32604/biocell.2023.026182","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"47 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79266087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.025930
Momina Shahid, K. Rehman, Muhammad Sajid Hamid Akash, Shaleem Suhail, S. Rasheed, Muhammad Imran, Mohammed A. ASSIRI
{"title":"Biochemical association between the prevalence of genetic polymorphism and myocardial infarction","authors":"Momina Shahid, K. Rehman, Muhammad Sajid Hamid Akash, Shaleem Suhail, S. Rasheed, Muhammad Imran, Mohammed A. ASSIRI","doi":"10.32604/biocell.2023.025930","DOIUrl":"https://doi.org/10.32604/biocell.2023.025930","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"4 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82211132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"KIF15, a key regulator of nasopharyngeal carcinoma development mediated by the P53 pathway","authors":"Yongliwang, S. Qu, Yong Yang, Ying Qin, Fei Liu, Guangwu Huang","doi":"10.32604/biocell.2023.025280","DOIUrl":"https://doi.org/10.32604/biocell.2023.025280","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"86 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82424938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.027971
Miaomiao Li, Z. Zheng, Junyi Ke, Jieyi Luo, Fan Jiang, Yan-xia Qu, B. Zhu, Yinghua Li, Liandong Zuo
{"title":"Inhibition of H2O2-induced TM3 cell apoptosis by oxidative stress by lentinan functionalized selenium nanoparticles through JAK2/STAT-3 and P53 pathways","authors":"Miaomiao Li, Z. Zheng, Junyi Ke, Jieyi Luo, Fan Jiang, Yan-xia Qu, B. Zhu, Yinghua Li, Liandong Zuo","doi":"10.32604/biocell.2023.027971","DOIUrl":"https://doi.org/10.32604/biocell.2023.027971","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"30 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83351544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.026631
Juan C. STOCKERT, Silvina A. ROMERO, Marcelo N. FELIX-POZZI, Alfonso BL罿QUEZ-CASTRO
{"title":"In vivo polymerization of the dopamine-borate melanin precursor: A proof-of-concept regarding boron neutron-capture therapy for melanoma","authors":"Juan C. STOCKERT, Silvina A. ROMERO, Marcelo N. FELIX-POZZI, Alfonso BL罿QUEZ-CASTRO","doi":"10.32604/biocell.2023.026631","DOIUrl":"https://doi.org/10.32604/biocell.2023.026631","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"14 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83925267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.026911
Lakshana Sadu, R. Krishnan, R. L. Akshaya, I. Saranya, Udipt RANJAN DAS, Sneha Satishkumar, N. Selvamurugan
{"title":"Roles of miR-214 in bone physiology and disease","authors":"Lakshana Sadu, R. Krishnan, R. L. Akshaya, I. Saranya, Udipt RANJAN DAS, Sneha Satishkumar, N. Selvamurugan","doi":"10.32604/biocell.2023.026911","DOIUrl":"https://doi.org/10.32604/biocell.2023.026911","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"21 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91104154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.023787
Carlos Alberto-Silva, Ana CAROLINA DE ARAUJO, Rodrigo SIM鉕 BONFIM, Joyce MEIRE GILIO
Bothrops envenomation is complex and provokes prominent local tissue damage and systemic disturbances, but little is known about their effects on the male reproductive system. After intratesticular injection, the bioactive peptide fraction (Bj-PF) obtained from Bothrops jararaca snake venom changes the structure of different stages of the seminiferous epithelium cycle in adult mice. For the first time, we investigated whether local envenomation of Bj-PF induces toxicological effects on the male reproductive system, particularly on the seminiferous epithelium and Sertoli cells. Male adult mice were treated with 0.24 mg.kg by intramuscular (i.m.) injection for 24 h. The testes samples were collected for morphological and morphometric evaluation. The toxicological effects of Bj-PF were also analyzed on mitochondrial metabolism and nitrite (NO2) production in 15P-1 Sertoli cell culture. Bj-PF changed the structure and function of the seminiferous epithelium, particularly the disruption of the epithelium and the presence of degenerated germ cells in the adluminal compartment, but there were no alterations in the basal compartment. Bj-PF increased the thickness of the seminiferous epithelium and decreased the lumen diameter of the tubule. Semiquantitative histological assessment of the degree of tubule degeneration revealed that Bj-PF also increased the number of hypospermatogenic tubules compared to control. Bj-PF reduced NO2 levels in 15P-1 Sertoli cells without changing the mitochondrial metabolism. Overall, the fact that Bj-PF alters the structure and function of the seminiferous epithelium suggests that bioactive peptides found in B. jararaca snake venom can have toxicological effects on the reproductive systems of affected male mice, providing new insight into the biological characteristics of snake venom and therapeutic strategies for envenomation inflammation.
{"title":"The peptide fraction of Bothrops jararaca snake venom induces toxicological effects on the male reproductive system after local envenomation in mice","authors":"Carlos Alberto-Silva, Ana CAROLINA DE ARAUJO, Rodrigo SIM鉕 BONFIM, Joyce MEIRE GILIO","doi":"10.32604/biocell.2023.023787","DOIUrl":"https://doi.org/10.32604/biocell.2023.023787","url":null,"abstract":"Bothrops envenomation is complex and provokes prominent local tissue damage and systemic disturbances, but little is known about their effects on the male reproductive system. After intratesticular injection, the bioactive peptide fraction (Bj-PF) obtained from Bothrops jararaca snake venom changes the structure of different stages of the seminiferous epithelium cycle in adult mice. For the first time, we investigated whether local envenomation of Bj-PF induces toxicological effects on the male reproductive system, particularly on the seminiferous epithelium and Sertoli cells. Male adult mice were treated with 0.24 mg.kg by intramuscular (i.m.) injection for 24 h. The testes samples were collected for morphological and morphometric evaluation. The toxicological effects of Bj-PF were also analyzed on mitochondrial metabolism and nitrite (NO2) production in 15P-1 Sertoli cell culture. Bj-PF changed the structure and function of the seminiferous epithelium, particularly the disruption of the epithelium and the presence of degenerated germ cells in the adluminal compartment, but there were no alterations in the basal compartment. Bj-PF increased the thickness of the seminiferous epithelium and decreased the lumen diameter of the tubule. Semiquantitative histological assessment of the degree of tubule degeneration revealed that Bj-PF also increased the number of hypospermatogenic tubules compared to control. Bj-PF reduced NO2 levels in 15P-1 Sertoli cells without changing the mitochondrial metabolism. Overall, the fact that Bj-PF alters the structure and function of the seminiferous epithelium suggests that bioactive peptides found in B. jararaca snake venom can have toxicological effects on the reproductive systems of affected male mice, providing new insight into the biological characteristics of snake venom and therapeutic strategies for envenomation inflammation.","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"103 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89923489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32604/biocell.2023.026930
Xiaohong Fu, Jie Zhao, D. Cao, Chengxing He, Ziyi Wang, Yibei Jiang, Jianfeng Liu, Guixi Liu
{"title":"Characteristics and expression of the TCP transcription factors family in Allium senescens reveal its potential roles in drought stress responses","authors":"Xiaohong Fu, Jie Zhao, D. Cao, Chengxing He, Ziyi Wang, Yibei Jiang, Jianfeng Liu, Guixi Liu","doi":"10.32604/biocell.2023.026930","DOIUrl":"https://doi.org/10.32604/biocell.2023.026930","url":null,"abstract":"","PeriodicalId":55384,"journal":{"name":"Biocell","volume":"7 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88980060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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