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[Intermediate butterfly osteotomy with rigid external distraction in Crouzon syndromes]. [中间蝶形截骨术+刚性外牵张治疗Crouzon综合征]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-10-22 DOI: 10.1016/j.anplas.2025.09.005
J Saboye

In Crouzon syndromes, there is an hypoplasia of the midface. An intermediate midfacial osteotomy between Lefort 2 and Lefort 3, called "butterfly osteotomy", associated wit a rigid external distraction on a Pooley helmet allows to pull the entire middle maxillary, orbital and zygomatic level in one step, and to project the tip of the nose, by a single endobuccal approach. The osteotomy concerns the entire middle level of the face while respecting the upper part of the nose. The external distractor with cranial support makes it possible to reposition the face, corrects the open bite and project the tip of the nose. This technique brings a ventilatory improvement in sleep apnea syndromes and an aesthetic improvement, beneficial on a psychological level.

在Crouzon综合征中,面部中部发育不全。在Lefort 2和Lefort 3之间的中间面中截骨术,称为“蝴蝶截骨术”,与Pooley头盔上的刚性外部牵张相结合,可以一步拉出整个上颌中部,眶和颧骨水平,并通过单次颊内入路突出鼻尖。截骨术涉及整个脸的中间部分,而尊重鼻子的上部。颅骨支撑的外部牵张器使面部重新定位、矫正开口咬合和突出鼻尖成为可能。这项技术改善了睡眠呼吸暂停综合症的通气,改善了审美,在心理层面上是有益的。
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引用次数: 0
[Management of venous malformations: A prospective study of 33 cases]. 静脉畸形的治疗:33例的前瞻性研究。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-10-16 DOI: 10.1016/j.anplas.2025.09.008
G Belmaati Cherkaoui, D Ar Reyouchi, I Kamaoui, A Benzirar, O El Mahi, A A Oufkir

Objective: Determine the epidemiology and frequency of complications, and compare the efficacy of different therapeutic approaches.

Methods: This prospective study included patients with venous malformation (VM) treated at the Vascular Anomalies Center between 2019 and 2023.

Results: Thirty-three patients were included in this study. The median age of the patients was 20 years, 17 patients were born with VM. 63% had symptomatic VM. The most common location was the face (42%). Aesthetic impact was significant in patients under 12 years old (P=0.01) and in the cephalic extremity (P=0.000). Treatment was initiated only in cases of symptomatic VM or with aesthetic impact. Compression garments were used in 6 patients, sclerotherapy in 14 patients, including 2 after surgery, and surgery in 16 patients, including 5 after non-successful sclerotherapy. Two patients received curative Low molecular weight heparin (LMWH) injection. Sirolimus was prescribed to 4 patients. These treatments resulted in complete regression in 10 patients and partial improvement in 12, with failure or recurrence in 7.

Conclusion: Most patients present with symptomatic VM with a functional or aesthetic impact. This study underlines the difficulty of managing VM, which must be adapted on a case-by-case basis, and confirms that medical and contention treatments can only bring about an often-transient improvement in symptoms. Only complete surgical excision can provide definitive cure.

目的:了解并发症的流行病学及发生频率,比较不同治疗方法的疗效。方法:这项前瞻性研究纳入了2019年至2023年在血管异常中心治疗的静脉畸形(VM)患者。结果:33例患者纳入本研究。患者中位年龄为20岁,17例为先天性VM。63%有症状性VM。最常见的部位是面部(42%)。12岁以下患者和头端患者的审美影响显著(P=0.01)。只有在有症状的VM或有美观影响的情况下才开始治疗。6例患者使用压缩服,14例患者使用硬化治疗,其中2例术后使用,16例患者使用手术治疗,其中5例硬化治疗不成功。2例患者接受治疗性低分子肝素(LMWH)注射。4例患者使用西罗莫司治疗。这些治疗导致10例患者完全消退,12例患者部分改善,7例患者失败或复发。结论:大多数患者表现为症状性VM,并伴有功能或美观影响。这项研究强调了管理VM的困难,必须根据具体情况进行调整,并证实医学和争论治疗只能带来通常是短暂的症状改善。只有完全的手术切除才能彻底治愈。
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引用次数: 0
Comparison of WALANT (Wide Awake Local Anesthesia Without Tourniquet) technique and infraclavicular brachial plexus block in cubital tunnel decompression surgery. 宽醒局麻无止血带技术与锁骨下臂丛阻滞在肘管减压手术中的比较。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-10-03 DOI: 10.1016/j.anplas.2025.08.001
A Acar, A B Acar, N Yılmaz, Ö Torun, A B Girgin, H B Çevik

Purpose: This study aimed to compare the efficacy of the WALANT (WA) technique with the infraclavicular brachial plexus block (IBPB) in patients undergoing anterior transposition and decompression of the ulnar nerve.

Methods: A total of 46 patients were included in this bicentric retrospective study. Twenty-two were in WA, 24 were in IBPB group. WA was done by a hand surgeon and IBPB was done by an anesthesiologist under ultrasonography guidance. The two groups were compared regarding demographic data, clinical results, and radiological outcomes.

Results: Preoperative preparation time and hospital stay were shorter in the WA group. VAS values at the 1st, 6th and 72nd hours after surgery were lower in the WA group. Intraoperative VAS-A values were higher in the WALANT group. Postoperative VAS-A values at the 6th hour were lower in the WA group. Return to work time was shorter in the WA group.

Conclusion: The WA technique in CuTS surgery is a method that can be easily applied, is safe and is not inferior to IBPB in terms of clinical results. WA shortens preoperative patient preparation time, pain, host stay, operating room usage and return to work time after CuTS surgery.

目的:本研究旨在比较WALANT (WA)技术与锁骨下臂丛神经阻滞(IBPB)技术在尺神经前移位减压患者中的疗效。方法:共纳入46例患者进行双中心回顾性研究。WA组22例,IBPB组24例。WA由手外科医生完成,IBPB由麻醉师在超声指导下完成。比较两组的人口学数据、临床结果和放射学结果。结果:WA组术前准备时间短,住院时间短。WA组术后1、6、72小时VAS值较低。WALANT组术中VAS-A值较高。WA组术后第6小时VAS-A值较低。WA组的复工时间较短。结论:WA技术在切口手术中应用方便、安全,临床效果不逊于IBPB。WA缩短了术前患者准备时间、疼痛、住院时间、手术室使用时间和cut手术后重返工作岗位的时间。
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引用次数: 0
[Jacques Joseph (1865-1934): The turning point. Part II: From rhinopoïesis to rhinoplasty]. 雅克·约瑟夫(1865-1934):转折点。第二部分:从rhinopoïesis到鼻整形]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-10-01 DOI: 10.1016/j.anplas.2025.08.003
Y Jallut

A new dimension in rhinoplasty emerged at the end of the 19th century, cosmetic surgery. Some authors recognized the importance of responding to the growing demand for cosmetic surgery, particularly for the nose. Although not the first, Joseph brought a new approach to rhinoplasty by laying the foundations for a technique that would later be known as the "structural technique", involving the resection and reduction of a pre-existing structure, beginning with the dorsal hump. Throughout his career, Joseph fought hard to impose his ideas and gain recognition from his peers despite not having a university education. His surgical skill and innovative spirit earned him the admiration of all who visited him, despite his sometimes challenging personality. His dexterity with a scalpel was matched only by his skill with a pen. In a difficult political and social context, he was a prolific author who wrote well-organised texts, thus facilitating the transmission of his knowledge and immense experience. For this reason, he fully deserves the title of "Father of Modern Rhinoplasty".

鼻整形术的一个新领域出现在19世纪末,那就是整容手术。一些作者认识到应对日益增长的整容手术需求的重要性,尤其是鼻子整形手术。虽然不是第一个,但约瑟夫带来了一种新的隆鼻方法,为后来被称为“结构技术”的技术奠定了基础,包括从背峰开始切除和缩小原有结构。在他的整个职业生涯中,尽管没有受过大学教育,但约瑟夫努力将自己的想法强加于人,并获得同龄人的认可。他的手术技巧和创新精神为他赢得了所有来访者的钦佩,尽管他有时具有挑战性的个性。他使用手术刀的熟练程度只有用笔的熟练程度能与之媲美。在困难的政治和社会背景下,他是一位多产的作家,他写了组织良好的文本,从而促进了他的知识和丰富经验的传播。因此,他完全配得上“现代隆鼻术之父”的称号。
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引用次数: 0
Transwomen satisfaction after nonsurgical management of large lower face with botulinum toxin injection of the masseter: A preliminary FACE-Q study. 跨性别女性使用咬肌注射肉毒杆菌毒素非手术治疗下面部后的满意度:一项初步的face - q研究。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-09-29 DOI: 10.1016/j.anplas.2025.09.003
M Slimani, E Ramelli, L Azoulai, M Atlan, A G Lellouch, S Cristofari

Facial feminization can be considered as an essential element of gender-affirming care and overall well-being of transgender women. This study explores a nonsurgical approach to facial gender-affirming procedures (FGAP) by assessing the efficacy of botulinum toxin (BT) injection for lower face transversal reduction. This cosmetic procedure was evaluated by administering the FACE-Q survey to participants, both pre- and post-procedure and at the three-month follow-up visit. A significant improvement in satisfaction was observed concerning the lower face appearance after BT injection in the masseter (P<0.001). These findings raise awareness towards alternative nonsurgical options in achieving lower facial feminization.

面部女性化可以被认为是性别确认护理和跨性别女性整体福祉的基本要素。本研究通过评估肉毒杆菌毒素(BT)注射下面部横向复位的疗效,探讨了一种非手术方法进行面部性别确认手术(FGAP)。通过对参与者在手术前后和三个月的随访中进行FACE-Q调查来评估这一美容手术。在咬肌注射BT后,下面部外观满意度显著提高(P
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引用次数: 0
[The role of perforator flaps in the management of pelvic-trochanteric pressure ulcers. Literature review and proposal of a treatment algorithm]. 穿支皮瓣在治疗盆腔-粗隆压疮中的作用。文献综述及一种治疗算法的提出]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-08-13 DOI: 10.1016/j.anplas.2025.06.019
P Rouchaleou, B Chaput, R Sinna, F Bekara, F Boissiere, R Capatina, A Ramon, S Fluieraru, A Gelis, C Herlin

Introduction: Surgery for pelvic-trochanteric pressure ulcers requires complex multidisciplinary management. Perioperative complications are common, as are distant recurrences. Perforator flaps are currently widely used for this indication, with the main advantages being that they avoid muscle sacrifice, reduce skin detachment in useful perforasomes, and shift the skin tension associated with remote removal of the pressure ulcer.

Materials and methods: We conducted a systematic review of the literature and a retrospective study of patients treated in two French expert centres over the last nine years concerning the complication and recurrence rates of fasciocutaneous, musculocutaneous and perforating flaps. We used these data to propose a treatment algorithm for the use of perforator flaps in the therapeutic arsenal.

Results: Out of 1210 publications studied, 92 articles were selected covering 4105 patients. The overall complication rate was 23.9% (CI 95% 23.44-24.42) and the recurrence rate was 12.4% (CI 95% 11.90-12.82) with a significant advantage in both cases for perforator flaps. We included in our cohort study 416 flaps performed on 399 patients with spinal cord injuries between 2015 and 2024. A significant reduction in the recurrence rate was observed with the use of a perforator flap (OR 0.47 [0.30; 0.74], P=0.001).

Conclusion: Perforator flaps are an indispensable solution in the current therapeutic arsenal for pelvic-trochanteric pressure ulcers coverage. More reliable and reducing long-term recurrence, they do not replace other types of flaps, which remain highly indicated. Our algorithm allows for the use of different types of flaps with a view to preserving muscle and skin in a population at risk of recurrence.

盆腔-粗隆压疮的手术治疗需要复杂的多学科管理。围手术期并发症很常见,远处复发也很常见。穿孔皮瓣目前广泛用于这一适应症,其主要优点是避免肌肉牺牲,减少有用穿孔体的皮肤脱离,并改变与远程去除压疮相关的皮肤张力。材料和方法:我们对过去九年在法国两个专家中心接受治疗的患者进行了系统的文献回顾和回顾性研究,涉及筋膜皮瓣、肌肉皮瓣和穿孔皮瓣的并发症和复发率。我们利用这些数据提出了一种治疗算法,用于在治疗库中使用穿支皮瓣。结果:在研究的1210篇出版物中,选择了92篇文章,覆盖了4105例患者。总并发症发生率为23.9% (CI 95% 23.44-24.42),复发率为12.4% (CI 95% 11.90-12.82),两例穿支皮瓣均有明显优势。我们在队列研究中纳入了2015年至2024年间对399例脊髓损伤患者进行的416个皮瓣。使用穿支皮瓣可显著降低复发率(OR 0.47 [0.30;0.74, P = 0.001)。结论:穿支皮瓣是目前治疗盆腔-粗隆压迫性溃疡不可缺少的方法。更可靠和减少长期复发,它们不取代其他类型的皮瓣,仍然是高度推荐的。我们的算法允许使用不同类型的皮瓣,以保留有复发风险的人群的肌肉和皮肤。
{"title":"[The role of perforator flaps in the management of pelvic-trochanteric pressure ulcers. Literature review and proposal of a treatment algorithm].","authors":"P Rouchaleou, B Chaput, R Sinna, F Bekara, F Boissiere, R Capatina, A Ramon, S Fluieraru, A Gelis, C Herlin","doi":"10.1016/j.anplas.2025.06.019","DOIUrl":"https://doi.org/10.1016/j.anplas.2025.06.019","url":null,"abstract":"<p><strong>Introduction: </strong>Surgery for pelvic-trochanteric pressure ulcers requires complex multidisciplinary management. Perioperative complications are common, as are distant recurrences. Perforator flaps are currently widely used for this indication, with the main advantages being that they avoid muscle sacrifice, reduce skin detachment in useful perforasomes, and shift the skin tension associated with remote removal of the pressure ulcer.</p><p><strong>Materials and methods: </strong>We conducted a systematic review of the literature and a retrospective study of patients treated in two French expert centres over the last nine years concerning the complication and recurrence rates of fasciocutaneous, musculocutaneous and perforating flaps. We used these data to propose a treatment algorithm for the use of perforator flaps in the therapeutic arsenal.</p><p><strong>Results: </strong>Out of 1210 publications studied, 92 articles were selected covering 4105 patients. The overall complication rate was 23.9% (CI 95% 23.44-24.42) and the recurrence rate was 12.4% (CI 95% 11.90-12.82) with a significant advantage in both cases for perforator flaps. We included in our cohort study 416 flaps performed on 399 patients with spinal cord injuries between 2015 and 2024. A significant reduction in the recurrence rate was observed with the use of a perforator flap (OR 0.47 [0.30; 0.74], P=0.001).</p><p><strong>Conclusion: </strong>Perforator flaps are an indispensable solution in the current therapeutic arsenal for pelvic-trochanteric pressure ulcers coverage. More reliable and reducing long-term recurrence, they do not replace other types of flaps, which remain highly indicated. Our algorithm allows for the use of different types of flaps with a view to preserving muscle and skin in a population at risk of recurrence.</p>","PeriodicalId":55512,"journal":{"name":"Annales De Chirurgie Plastique Esthetique","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The submental flap: Anatomical study of pedicle elongation]. [颏下皮瓣:蒂延伸的解剖学研究]。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-08-12 DOI: 10.1016/j.anplas.2025.06.011
F Dupuy, H Oubari, H Despert, G Henry, A Mojallal, L Brochet

Introduction: Martin's first description of the submental flap in 1990 (Martins, 1990) made it possible to reliably cover the lower two-thirds of the face. Although deemed difficult due to its intricated vascular, muscular and nerve anatomy, this flap has quickly gained in popularity. Its increasingly frequent use has made it possible to describe dissection steps at the level of the facial vessels and venous drainage system to gain arc of rotation. However, to date, no study has measured the gain in arc of rotation related of the dissection performed.

Objective: To find out the gain in arc of rotation depending of the dissection performed at arterial and venous level. We also describe the course of the submental artery in relation to the anterior belly of the digastric muscle.

Method: Twelve flaps were made on six fresh cadavers, previously injected with colored latex. Measurements were taken with a reference line between the external canthus and the root of the helix.

Results: Of the eleven flaps including the submental artery, dissection of the facial artery to its origin at the level of the external carotid artery resulted in an average gain of 2.3cm. The YV venous lengthening resulted in an additional average gain of 0.8cm. In all cases, the submental artery was located deeper than the anterior belly of the digastric muscle.

Conclusion: Pedicle elongation techniques include dissection of the facial artery to its origin, as well as YV venous procedure. The choice should be dictated by the area to be covered. The gain in arc of rotation is substantial after dissection of the facial artery and appears moderate and technically difficult with venous lengthening.

简介:Martin在1990年首次描述颏下皮瓣(Martins, 1990),使其能够可靠地覆盖面部的下三分之二。尽管由于其复杂的血管、肌肉和神经解剖结构而被认为是困难的,但这种皮瓣很快就得到了普及。它的日益频繁的使用,使得有可能描述解剖步骤在面血管和静脉引流系统的水平,以获得旋转弧度。然而,到目前为止,还没有研究测量与解剖相关的旋转弧度增益。目的:探讨在动脉和静脉水平进行解剖时,旋转弧度的增益。我们还描述了与二腹肌前腹有关的颏下动脉的路线。方法:在6具新鲜尸体上制作12个皮瓣,之前注射了彩色乳胶。测量采用外眦和螺旋根部之间的参考线。结果:包括颏下动脉在内的11个皮瓣中,在颈外动脉水平处对面动脉至其起源处进行剥离,平均增加2.3cm。YV静脉延长导致平均增加0.8cm。在所有病例中,颏下动脉位于比二腹肌前腹更深的位置。结论:椎弓根延伸技术包括面动脉的起源分离,以及YV静脉手术。该选择应由所覆盖的区域决定。面动脉剥离后,旋转弧度的增加是显著的,静脉延长后,旋转弧度的增加是适度的,在技术上是困难的。
{"title":"[The submental flap: Anatomical study of pedicle elongation].","authors":"F Dupuy, H Oubari, H Despert, G Henry, A Mojallal, L Brochet","doi":"10.1016/j.anplas.2025.06.011","DOIUrl":"https://doi.org/10.1016/j.anplas.2025.06.011","url":null,"abstract":"<p><strong>Introduction: </strong>Martin's first description of the submental flap in 1990 (Martins, 1990) made it possible to reliably cover the lower two-thirds of the face. Although deemed difficult due to its intricated vascular, muscular and nerve anatomy, this flap has quickly gained in popularity. Its increasingly frequent use has made it possible to describe dissection steps at the level of the facial vessels and venous drainage system to gain arc of rotation. However, to date, no study has measured the gain in arc of rotation related of the dissection performed.</p><p><strong>Objective: </strong>To find out the gain in arc of rotation depending of the dissection performed at arterial and venous level. We also describe the course of the submental artery in relation to the anterior belly of the digastric muscle.</p><p><strong>Method: </strong>Twelve flaps were made on six fresh cadavers, previously injected with colored latex. Measurements were taken with a reference line between the external canthus and the root of the helix.</p><p><strong>Results: </strong>Of the eleven flaps including the submental artery, dissection of the facial artery to its origin at the level of the external carotid artery resulted in an average gain of 2.3cm. The YV venous lengthening resulted in an additional average gain of 0.8cm. In all cases, the submental artery was located deeper than the anterior belly of the digastric muscle.</p><p><strong>Conclusion: </strong>Pedicle elongation techniques include dissection of the facial artery to its origin, as well as YV venous procedure. The choice should be dictated by the area to be covered. The gain in arc of rotation is substantial after dissection of the facial artery and appears moderate and technically difficult with venous lengthening.</p>","PeriodicalId":55512,"journal":{"name":"Annales De Chirurgie Plastique Esthetique","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144849718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revue de presse 新闻评论
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-08-12 DOI: 10.1016/j.anplas.2025.07.002
{"title":"Revue de presse","authors":"","doi":"10.1016/j.anplas.2025.07.002","DOIUrl":"10.1016/j.anplas.2025.07.002","url":null,"abstract":"","PeriodicalId":55512,"journal":{"name":"Annales De Chirurgie Plastique Esthetique","volume":"70 5","pages":"Pages 448-450"},"PeriodicalIF":0.5,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144917104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D bioprinting in regenerative medicine: From skin to organ engineering. 再生医学中的生物3D打印:从皮肤到器官工程。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-08-11 DOI: 10.1016/j.anplas.2025.06.013
D Haykal, A-C Benhamou, T Lotti, F Duteille

3D skin bioprinting is a transformative innovation in regenerative medicine, offering new possibilities for wound healing, reconstructive surgery, and disease modeling. By enabling the precise fabrication of patient-specific skin grafts, this technology addresses critical medical challenges, including severe burns, chronic ulcers, traumatic injuries, and genetic skin disorders. Advances in bioprinting techniques, bioink formulations, and vascularization strategies have enhanced graft integration and functional restoration, avoiding immune rejection risks. Beyond transplantation, 3D skin models provide a powerful platform for dermatological research, pharmacological testing, and tissue engineering, accelerating drug discovery while minimizing reliance on animal testing. Additionally, 3D bioprinting is revolutionizing cosmetic and reconstructive dermatology, enabling personalized aesthetic procedures, scar treatments, and anti-aging interventions that complement clinical applications. The future of 3D skin bioprinting lies in multi-tissue fabrication, AI-assisted biofabrication, and immunomodulatory grafts, which could revolutionize personalized medicine and regenerative healthcare. Despite ongoing challenges in clinical scalability and regulatory pathways, continued interdisciplinary research is driving the field closer to real-world medical applications. This review provides a structured timeline of advancements, compares bioprinting techniques, and offers specific examples of clinical and commercial applications. It concludes with a discussion of future directions, emphasizing sustainable bioinks, AI-assisted fabrication, and ethical frameworks.

3D皮肤生物打印是再生医学的革命性创新,为伤口愈合、重建手术和疾病建模提供了新的可能性。通过精确制造患者特异性皮肤移植物,这项技术解决了关键的医疗挑战,包括严重烧伤、慢性溃疡、创伤性损伤和遗传性皮肤疾病。生物打印技术、生物链接配方和血管化策略的进步增强了移植物的整合和功能恢复,避免了免疫排斥风险。除了移植,3D皮肤模型为皮肤学研究、药理学测试和组织工程提供了一个强大的平台,加速了药物发现,同时最大限度地减少了对动物试验的依赖。此外,3D生物打印正在彻底改变美容和重建皮肤病学,使个性化美容程序,疤痕治疗和抗衰老干预成为临床应用的补充。3D皮肤生物打印的未来在于多组织制造、人工智能辅助生物制造和免疫调节移植,这可能会彻底改变个性化医疗和再生医疗。尽管在临床可扩展性和监管途径方面面临着持续的挑战,但持续的跨学科研究正在推动该领域更接近现实世界的医疗应用。这篇综述提供了一个结构化的进展时间表,比较了生物打印技术,并提供了临床和商业应用的具体例子。最后讨论了未来的发展方向,强调可持续生物墨水、人工智能辅助制造和伦理框架。
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引用次数: 0
Bilateral breast reconstruction with a two-stage DIEP flap: A single-center experience. 双期DIEP皮瓣双侧乳房重建:单中心经验。
IF 0.5 4区 医学 Q4 SURGERY Pub Date : 2025-08-07 DOI: 10.1016/j.anplas.2025.06.009
I Salazar, A Fernández, D Luis, M A Cálix García

Background: The deep inferior epigastric perforator flap (DIEP) is the gold standard for autologous breast reconstruction (ABR), but its viability can be challenged in resource-reduced environments like Mexico, where bilateral DIEP reconstructions are rare due to their complexity. A two-stage procedure has been introduced to improve flap viability and mitigate surgeon-related factors.

Objective: This study is to describe the two-stage technique to improve flap survival in bilateral DIEP flap reconstructions and to report the results in a center with limited hours and resources.

Methods: A retrospective case series included women aged≥18years who underwent two-stage bilateral DIEP flap procedures, either immediately or delayed, from January 2021 to July 2024. Key variables assessed included flap success rates, demographics, risk factors, complications, and surgical times.

Results: Twenty breasts were reconstructed in 10 patients. The mean age was 49.5years, 4 were smokers, 3 had prior abdominal surgeries, and 7 had received radiotherapy. The first-stage surgery averaged 145.5minutes, with a 4.3-day interval before the second stage, which lasted 243minutes. The overall flap success was 100%, with one case of partial flap loss, which did not compromise the final outcome. Complications included wound dehiscence (10%) and venous congestion (5%). The average hospital stay was 9.6days.

Conclusions: The two-stage DIEP flap technique is a viable option for high-risk patients, yielding satisfactory outcomes and reducing complications. This method addresses surgeon-related challenges, enhancing overall results. Further research on flap delay in free flaps is recommended for improved practices in difficult settings.

背景:深下腹穿支皮瓣(DIEP)是自体乳房重建(ABR)的金标准,但在墨西哥等资源匮乏的环境中,其可行性受到挑战,在那里双侧DIEP重建因其复杂性而罕见。一个两阶段的程序已被介绍,以提高皮瓣的活力和减轻手术相关的因素。目的:本研究描述双侧DIEP皮瓣重建的两阶段技术,以提高皮瓣存活率,并在时间和资源有限的中心报告结果。方法:回顾性病例系列包括年龄≥18岁的女性,于2021年1月至2024年7月期间立即或延迟接受两期双侧DIEP皮瓣手术。评估的关键变量包括皮瓣成功率、人口统计学、危险因素、并发症和手术时间。结果:10例患者重建乳房20个。平均年龄49.5岁,吸烟4人,既往腹部手术3人,放疗7人。第一阶段手术平均145.5分钟,第二阶段手术间隔4.3天,持续243分钟。皮瓣整体成功率为100%,有1例部分皮瓣丢失,但不影响最终结果。并发症包括伤口裂开(10%)和静脉充血(5%)。平均住院时间9.6天。结论:二级DIEP皮瓣技术是高危患者的可行选择,可获得满意的结果并减少并发症。这种方法解决了与外科手术相关的挑战,提高了整体效果。进一步研究皮瓣延迟自由皮瓣推荐改进的做法,在困难的设置。
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引用次数: 0
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Annales De Chirurgie Plastique Esthetique
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