{"title":"Genome-wide CRISPR/Cas9 Screening Identifies KDM2B as a Modifier of Heparan Sulfate–Protein Interactions","authors":"Haruki Odaka","doi":"10.4052/tigg.2203.6e","DOIUrl":"https://doi.org/10.4052/tigg.2203.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42243490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"α-Selective Dehydrative Glycosylation of 2-Deoxy- and 2,6-Dideoxy Sugars Using Cyclic Geminal Dihalides","authors":"Nozomi Ishii","doi":"10.4052/tigg.2205.6e","DOIUrl":"https://doi.org/10.4052/tigg.2205.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46578800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipid Conjugates as Ligands for the C-type Lectin Receptor Mincle","authors":"Takanori Matsumaru","doi":"10.4052/tigg.2029.1e","DOIUrl":"https://doi.org/10.4052/tigg.2029.1e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48025929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiological Significance of Animal- and Tissue-specific Sialic Acid Composition","authors":"Yuko Naito-Matsui","doi":"10.4052/tigg.2036.1e","DOIUrl":"https://doi.org/10.4052/tigg.2036.1e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47756029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Crystal Structure Analysis and Inhibitor Search of Ergosteryl Glucoside Hydrolase of Cryptococcus neoformans for Antifungal Drug Development","authors":"Takashi Watanabe","doi":"10.4052/tigg.2134.6j","DOIUrl":"https://doi.org/10.4052/tigg.2134.6j","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46372241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In in vitro studies, chondroitin sulfate E (CSE) has been found to have various activities, suggesting its importance in the living body. However, the in vitro function of CSE has not been fully elucidated. Antibodies have been used as a tool for assessing the biological roles of sugar chains, but previously reported antibodies react not only with CSE but also with other CS isomers. If an antibody was highly specific and able to detect only CSE, it could be used to study the in vitro activities of CSE or as a probe for detecting diseases marked by abnormal expression or localization of CSE. This paper outlines the properties of antibodies that react with CSE.
在体外研究中，硫酸软骨素E (chondroitin sulfate E, CSE)已被发现具有多种活性，表明其在生物体内的重要性。然而，CSE的体外功能尚未完全阐明。抗体已被用作评估糖链生物学作用的工具，但先前报道的抗体不仅与CSE反应，还与其他CS异构体反应。如果一种抗体具有高度特异性且仅能检测CSE，则可用于研究CSE的体外活性或作为检测以CSE异常表达或定位为标志的疾病的探针。本文概述了与CSE反应的抗体的性质。
{"title":"Properties of Monoclonal Antibodies Recognizing Chondroitin Sulfate E","authors":"Ippei Watanabe","doi":"10.4052/tigg.2120.1j","DOIUrl":"https://doi.org/10.4052/tigg.2120.1j","url":null,"abstract":"In in vitro studies, chondroitin sulfate E (CSE) has been found to have various activities, suggesting its importance in the living body. However, the in vitro function of CSE has not been fully elucidated. Antibodies have been used as a tool for assessing the biological roles of sugar chains, but previously reported antibodies react not only with CSE but also with other CS isomers. If an antibody was highly specific and able to detect only CSE, it could be used to study the in vitro activities of CSE or as a probe for detecting diseases marked by abnormal expression or localization of CSE. This paper outlines the properties of antibodies that react with CSE.","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42004542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mourning Professor William Joseph Lennarz (1934–2021)","authors":"Yoichiro Harada","doi":"10.4052/tigg.2133.7j","DOIUrl":"https://doi.org/10.4052/tigg.2133.7j","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44523071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FUT8-mediated Aberrant N-glycosylation of B7H3 Suppresses Antitumor Immunity in Triple-negative Breast Cancer","authors":"Tsukasa Shigehiro","doi":"10.4052/tigg.2202.6e","DOIUrl":"https://doi.org/10.4052/tigg.2202.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48321625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"LYTAC: Membrane/Extracellular Protein Degradation","authors":"Y. Manabe","doi":"10.4052/tigg.2131.6e","DOIUrl":"https://doi.org/10.4052/tigg.2131.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":"1 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41433150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation of Leptin Receptor Signaling by Gangliosides","authors":"K. Inamori","doi":"10.4052/tigg.2106.1e","DOIUrl":"https://doi.org/10.4052/tigg.2106.1e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44170061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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