Over 150 years, fluorescence probes have remained a cornerstone for selective detection and imaging a wide range of analytes. Unlike classical monochromatic probes, ratiometric fluorescence probes (RFPs) can self-correct data distortion. In the 75th year celebration of excited state intramolecular proton transfer (ESIPT) and its new role, ESIPT-RFPs and imaging agents provide dual confirmatory signals. RFPs are characterized by their major sensing mechanisms, including ICT, FRET, ESIPT, and monomer-excimer formation. In recent years, researchers have widely studied ESIPT-RFPs for various environmental and biological analytes, including anions, cations, and neutral analytes. As a result, several reports discuss the ESIPT-RFP for detecting and monitoring a numerous of environmental analytes. The 2-hydroxyphenyl benzothiazole and 3-hydroxy flavones ESIPT cores are most widely utilized for the design. This review examines the diverse mechanisms employed for sensing and signal changes of ESIPT-RFPs for environmental detection and monitoring, focusing on neutral molecules, anions, and cations. The ESIPT-RFP probes have two types of sensing signals: two reversible signals and fixed reference signals, which can be red-shifted or blue-shifted. The ESIPT-RFP sensing mechanisms are categorized into Types I, II, and III. This article reviews over 88 published articles on ESIPT-based RFPs for environmental detection and monitoring.
{"title":"Recent progress in excited-state intramolecular proton transfer-based ratiometry fluorescence probes for environmental detection and monitoring","authors":"Savikriti Saini , Selva Kumar Ramasamy , S.K. Ashok Kumar","doi":"10.1016/j.teac.2025.e00279","DOIUrl":"10.1016/j.teac.2025.e00279","url":null,"abstract":"<div><div>Over 150 years, fluorescence probes have remained a cornerstone for selective detection and imaging a wide range of analytes. Unlike classical monochromatic probes, ratiometric fluorescence probes (RFPs) can self-correct data distortion. In the 75<sup>th</sup> year celebration of excited state intramolecular proton transfer (ESIPT) and its new role, ESIPT-RFPs and imaging agents provide dual confirmatory signals. RFPs are characterized by their major sensing mechanisms, including ICT, FRET, ESIPT, and monomer-excimer formation. In recent years, researchers have widely studied ESIPT-RFPs for various environmental and biological analytes, including anions, cations, and neutral analytes. As a result, several reports discuss the ESIPT-RFP for detecting and monitoring a numerous of environmental analytes. The 2-hydroxyphenyl benzothiazole and 3-hydroxy flavones ESIPT cores are most widely utilized for the design. This review examines the diverse mechanisms employed for sensing and signal changes of ESIPT-RFPs for environmental detection and monitoring, focusing on neutral molecules, anions, and cations. The ESIPT-RFP probes have two types of sensing signals: two reversible signals and fixed reference signals, which can be red-shifted or blue-shifted. The ESIPT-RFP sensing mechanisms are categorized into <strong>Types I</strong>, <strong>II</strong>, and <strong>III</strong>. This article reviews over 88 published articles on ESIPT-based RFPs for environmental detection and monitoring.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"48 ","pages":"Article e00279"},"PeriodicalIF":13.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144895103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-26DOI: 10.1016/j.teac.2025.e00277
Justyna Płotka-Wasylka , Justyna Werner , Agnieszka Zgoła-Grześkowiak , Monika Paszkiewicz , Klaudia Godlewska , Anna Białk-Bielińska , Aleksandra Kurowska-Susdorf , Suwijak Pantanit , Opas Bunkoed , Muhammad Sajid , Natalia Jatkowska
Hydrogel-based sorbents have emerged as excellent materials in analytical chemistry, especially in efforts toward a sustainable environment. These versatile substances, characterized by their high water absorption capacity and biocompatibility, are increasingly utilized for the selective extraction as well as the removal of various pollutants, including heavy metals and organic micro-pollutants, from environmental samples. Notably, the shift towards multifunctional hydrogels illustrates a commitment to synthesizing materials that perform well in diverse environmental conditions, reflecting a growing demand for eco-friendly analytical practices. This review covers information related to hydrogel-based sorbents with special emphasis on their utilization in both extraction processes and the removal of pollutants in the environment. It starts with the methods of synthesis of hydrogel-based sorbents considering the environmental impact, but also the evaluation of ecotoxicology of the hydrogel-based sorbent components is presented, together with economical aspects of synthesis and future processes. In addition, the application of hydrogel-based sorbents as the extractive medium as well as the medium for the removal of specific pollutants are deeply described with specific examples. In addition, the general discussion on enriching systems thinking and social sustainability through education is provided as we see this point as important from the society point of view.
{"title":"Milestones of hydrogel-based sorbents used in specific applications in analytical chemistry towards education for sustainable environment","authors":"Justyna Płotka-Wasylka , Justyna Werner , Agnieszka Zgoła-Grześkowiak , Monika Paszkiewicz , Klaudia Godlewska , Anna Białk-Bielińska , Aleksandra Kurowska-Susdorf , Suwijak Pantanit , Opas Bunkoed , Muhammad Sajid , Natalia Jatkowska","doi":"10.1016/j.teac.2025.e00277","DOIUrl":"10.1016/j.teac.2025.e00277","url":null,"abstract":"<div><div>Hydrogel-based sorbents have emerged as excellent materials in analytical chemistry, especially in efforts toward a sustainable environment. These versatile substances, characterized by their high water absorption capacity and biocompatibility, are increasingly utilized for the selective extraction as well as the removal of various pollutants, including heavy metals and organic micro-pollutants, from environmental samples. Notably, the shift towards multifunctional hydrogels illustrates a commitment to synthesizing materials that perform well in diverse environmental conditions, reflecting a growing demand for eco-friendly analytical practices. This review covers information related to hydrogel-based sorbents with special emphasis on their utilization in both extraction processes and the removal of pollutants in the environment. It starts with the methods of synthesis of hydrogel-based sorbents considering the environmental impact, but also the evaluation of ecotoxicology of the hydrogel-based sorbent components is presented, together with economical aspects of synthesis and future processes. In addition, the application of hydrogel-based sorbents as the extractive medium as well as the medium for the removal of specific pollutants are deeply described with specific examples. In addition, the general discussion on enriching systems thinking and social sustainability through education is provided as we see this point as important from the society point of view.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00277"},"PeriodicalIF":13.4,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-23DOI: 10.1016/j.teac.2025.e00275
Louise Durand, Laure Wiest, Emmanuelle Vulliet
Analytical chemistry plays a crucial role in environmental monitoring, yet its own practices contribute to environmental degradation. To address this paradox, the emergence of the concepts of Green Analytical Chemistry (GAC), White Analytical Chemistry (WAC) and Green Sample Preparation (GSP) has led to the use of tools to evaluate analytical methods. Various tools have been developed to assess the environmental impact of analytical methods, including HPLC-EAT, AES, AMVI, GAPI, AMGS, RGB model and its evolutions, AGREE, AGREEprep, HEXAGON, LCA, SPMS and BAGI. They differ in their scope, assessment criteria, and methodological approach, from qualitative scoring systems to quantitative assessments. This review critically compares these tools, highlighting their strengths and limitations in evaluating sustainability across different stages of the analytical process. Particular attention is given to the assessment of chemical hazards, energy consumption, and impact quantification. The need for standardized, comprehensive, and accessible methodologies is emphasized to guide the transition toward truly sustainable analytical practices.
{"title":"Analytical chemistry in the era of sustainability: evaluating tools and challenges for a greener future","authors":"Louise Durand, Laure Wiest, Emmanuelle Vulliet","doi":"10.1016/j.teac.2025.e00275","DOIUrl":"10.1016/j.teac.2025.e00275","url":null,"abstract":"<div><div>Analytical chemistry plays a crucial role in environmental monitoring, yet its own practices contribute to environmental degradation. To address this paradox, the emergence of the concepts of Green Analytical Chemistry (GAC), White Analytical Chemistry (WAC) and Green Sample Preparation (GSP) has led to the use of tools to evaluate analytical methods. Various tools have been developed to assess the environmental impact of analytical methods, including HPLC-EAT, AES, AMVI, GAPI, AMGS, RGB model and its evolutions, AGREE, AGREEprep, HEXAGON, LCA, SPMS and BAGI. They differ in their scope, assessment criteria, and methodological approach, from qualitative scoring systems to quantitative assessments. This review critically compares these tools, highlighting their strengths and limitations in evaluating sustainability across different stages of the analytical process. Particular attention is given to the assessment of chemical hazards, energy consumption, and impact quantification. The need for standardized, comprehensive, and accessible methodologies is emphasized to guide the transition toward truly sustainable analytical practices.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00275"},"PeriodicalIF":13.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-23DOI: 10.1016/j.teac.2025.e00276
Mingyue Pan, Franc Paré, Mireia Baeza
After a brief introduction of the state of the art in environmental monitoring and 3D-printing technology, this review presents a general summary report about the most relevant electrochemical sensors fabricated by 3D-printing during the past five years. Being mainly applied in environmental monitoring, food industry and healthcare and pharmaceutical industry, the printing design, choice of electrode modification and analytical performance of those sensors are compared and discussed. Furthermore, to gain a better understanding about the achievements and limitations of the electrochemical sensors designed for environmental monitoring, a more detailed analysis is carried out by mainly focusing on water pollution detection and quality monitoring. Finally, to take better advantage of 3D-printing, the possible improvements and the future of further applying this technique into the environmental monitoring section is also discussed.
{"title":"3D-printed sensing platforms and their feasibility for environmental monitoring","authors":"Mingyue Pan, Franc Paré, Mireia Baeza","doi":"10.1016/j.teac.2025.e00276","DOIUrl":"10.1016/j.teac.2025.e00276","url":null,"abstract":"<div><div>After a brief introduction of the state of the art in environmental monitoring and 3D-printing technology, this review presents a general summary report about the most relevant electrochemical sensors fabricated by 3D-printing during the past five years. Being mainly applied in environmental monitoring, food industry and healthcare and pharmaceutical industry, the printing design, choice of electrode modification and analytical performance of those sensors are compared and discussed. Furthermore, to gain a better understanding about the achievements and limitations of the electrochemical sensors designed for environmental monitoring, a more detailed analysis is carried out by mainly focusing on water pollution detection and quality monitoring. Finally, to take better advantage of 3D-printing, the possible improvements and the future of further applying this technique into the environmental monitoring section is also discussed.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00276"},"PeriodicalIF":13.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-15DOI: 10.1016/j.teac.2025.e00274
Hamada B. Hawash
In recent years, 3D printing technology, or additive manufacturing, has attracted exceptional interest in several areas of research owing to its rapid prototyping capabilities, reduced fabrication time, one-step production process, and growing variety of functional printing plates. The 3D printing technology involves the sequential deposition or polymerization of thin layers of material to produce the intended object. Despite all 3D printers being designed for the same purpose, their dimensions, resolutions, compatible materials, post-manufacturing devices needed, and cost might differ significantly. Combining molecularly imprinted polymers (MIPs) with 3D printing technology (3D-MIPs) enables reproducible and scalable final fabricated systems. This work covers the advancements of the synergistic integration of 3D printing technology with MIPs for the polymerization phase to allow manufacturing materials with qualities precisely satisfied for the separation of organic and inorganic compounds from water matrices and different samples. The procedures and ideas involved in synthesizing 3D-MIPs are discussed, along with their substantial properties for environmental applications. Particular emphasis is focused on the efficiency of the prepared materials resulting from the designed 3D-MIPs compared to those of the individual entities.
{"title":"Recent advances in three-dimensional (3D) printing of molecularly imprinted polymers (MIPs) for potential environmental applications","authors":"Hamada B. Hawash","doi":"10.1016/j.teac.2025.e00274","DOIUrl":"10.1016/j.teac.2025.e00274","url":null,"abstract":"<div><div>In recent years, 3D printing technology, or additive manufacturing, has attracted exceptional interest in several areas of research owing to its rapid prototyping capabilities, reduced fabrication time, one-step production process, and growing variety of functional printing plates. The 3D printing technology involves the sequential deposition or polymerization of thin layers of material to produce the intended object. Despite all 3D printers being designed for the same purpose, their dimensions, resolutions, compatible materials, post-manufacturing devices needed, and cost might differ significantly. Combining molecularly imprinted polymers (MIPs) with 3D printing technology (3D-MIPs) enables reproducible and scalable final fabricated systems. This work covers the advancements of the synergistic integration of 3D printing technology with MIPs for the polymerization phase to allow manufacturing materials with qualities precisely satisfied for the separation of organic and inorganic compounds from water matrices and different samples. The procedures and ideas involved in synthesizing 3D-MIPs are discussed, along with their substantial properties for environmental applications. Particular emphasis is focused on the efficiency of the prepared materials resulting from the designed 3D-MIPs compared to those of the individual entities.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00274"},"PeriodicalIF":11.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phosphodiesterase type 5 (PDE5) inhibitors are widely used to treat erectile dysfunction and pulmonary hypertension. However, their safety has come under scrutiny due to frequent recalls by the U.S. Food and Drug Administration (FDA). These recalls often result from impurities, mislabelling, or unapproved ingredients, posing health risks to patients. This study aims to develop sustainable methods for the early detection of at-risk PDE5 inhibitors through green analytical chemistry concepts. A systematic review of literature from 2020 to 2024 identified over 2000 publications on Green Analytical Chemistry, including 121 focused on PDE5 inhibitors, from which 37 key analytical references were selected for detailed evaluation, consist of methods such as UV spectrophotometry, HPLC, and mass spectrometry. The research uses tools like AGREE, AGREEprep, GAPI, and BAGI to find eco-friendly methods for analysing PDE5 inhibitors. All published work on PDE5 inhibitor drugs evaluated using green analytical tools, and greenness scores were calculated to determine sustainable methods for quality control (QC) and to assess quality during manufacturing and post-market surveillance. The findings will support pharmacovigilance for manufacturers, regulators, providers, and consumers. The integration of green chemistry tools will also promote environmentally friendly practices, reducing the ecological footprint of pharmaceutical production. Overall, this research will support the development of safer, more sustainable medications, fostering greater trust among consumers and stakeholders in the healthcare industry.
{"title":"Sustainability assessment of PDE-5 inhibitor analysis: A comparative study using AGREE, AGREEPrep, Complex GAPI, and BAGI","authors":"Jeswin Maliyakal , Nidhi Vadnere , Sandesh Bherje, Mital Patel","doi":"10.1016/j.teac.2025.e00273","DOIUrl":"10.1016/j.teac.2025.e00273","url":null,"abstract":"<div><div>Phosphodiesterase type 5 (PDE5) inhibitors are widely used to treat erectile dysfunction and pulmonary hypertension. However, their safety has come under scrutiny due to frequent recalls by the U.S. Food and Drug Administration (FDA). These recalls often result from impurities, mislabelling, or unapproved ingredients, posing health risks to patients. This study aims to develop sustainable methods for the early detection of at-risk PDE5 inhibitors through green analytical chemistry concepts. A systematic review of literature from 2020 to 2024 identified over 2000 publications on Green Analytical Chemistry, including 121 focused on PDE5 inhibitors, from which 37 key analytical references were selected for detailed evaluation, consist of methods such as UV spectrophotometry, HPLC, and mass spectrometry. The research uses tools like AGREE, AGREEprep, GAPI, and BAGI to find eco-friendly methods for analysing PDE5 inhibitors. All published work on PDE5 inhibitor drugs evaluated using green analytical tools, and greenness scores were calculated to determine sustainable methods for quality control (QC) and to assess quality during manufacturing and post-market surveillance. The findings will support pharmacovigilance for manufacturers, regulators, providers, and consumers. The integration of green chemistry tools will also promote environmentally friendly practices, reducing the ecological footprint of pharmaceutical production. Overall, this research will support the development of safer, more sustainable medications, fostering greater trust among consumers and stakeholders in the healthcare industry.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00273"},"PeriodicalIF":11.1,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Synthetic antibiotics play an important role in livestock productivity and improve feed conversion rates by treating numerous animal-related diseases. The over-dosage of antibiotics to domestic animals has worsened antibiotic adulteration in food products, resulting in hazardous effects on humans and disturbing ecological and environmental systems. In this respect, establishing strict regulations and a positive list system (PLS), educating farmers, and fabricating simple, low-cost, rapid, non-invasive, pretreatment-free, and portable devices for precise, quick, and on-site recognition of antibiotics is undeniably essential and overdue. Such a device would adhere to the PLS guidelines, effectively detect maximum residue limits (MRLs), and protect both the environment and humans from the toxic effects of antibiotics. Here, we conduct a thorough review of the global status of PLS, its significance, and the latest advancements in research on on-site sensing strategies designed to detect antibiotics in livestock. Also, we address on-site sensing methods and analytical performances in detail and determine whether the limit of detection of described strategies meets MRL requirements. In addition, we describe future challenges, trends, perspectives, and analytical methods and provide an overview of sample extraction techniques. Current scientific and technological studies based on biomolecule and synthetic receptor-based sensors have considerably increased the ability to recognize antibiotics in livestock on-site. Colorimetric detection techniques offer the most potential for monitoring antibiotics in real time due to their straightforwardness, high selectivity, and sensitivity. This study highlights novel concepts, insights, and challenges associated with portable devices with potential use as simple paper-based sensors for detecting antibiotics in livestock.
{"title":"Advancements in pretreatment-free portable sensing approaches for antibiotics detection in non-invasive livestock samples: Assessment and requirement of positive list system regulations","authors":"Sonam Sonwal , Munirah Alhammadi , Soobin Han , Gagankumar Sakleshpur Kumar , Young-Kyu Han , Mi-Hwa Oh , Yun Suk Huh","doi":"10.1016/j.teac.2025.e00272","DOIUrl":"10.1016/j.teac.2025.e00272","url":null,"abstract":"<div><div>Synthetic antibiotics play an important role in livestock productivity and improve feed conversion rates by treating numerous animal-related diseases. The over-dosage of antibiotics to domestic animals has worsened antibiotic adulteration in food products, resulting in hazardous effects on humans and disturbing ecological and environmental systems. In this respect, establishing strict regulations and a positive list system (PLS), educating farmers, and fabricating simple, low-cost, rapid, non-invasive, pretreatment-free, and portable devices for precise, quick, and on-site recognition of antibiotics is undeniably essential and overdue. Such a device would adhere to the PLS guidelines, effectively detect maximum residue limits (MRLs), and protect both the environment and humans from the toxic effects of antibiotics. Here, we conduct a thorough review of the global status of PLS, its significance, and the latest advancements in research on on-site sensing strategies designed to detect antibiotics in livestock. Also, we address on-site sensing methods and analytical performances in detail and determine whether the limit of detection of described strategies meets MRL requirements. In addition, we describe future challenges, trends, perspectives, and analytical methods and provide an overview of sample extraction techniques. Current scientific and technological studies based on biomolecule and synthetic receptor-based sensors have considerably increased the ability to recognize antibiotics in livestock on-site. Colorimetric detection techniques offer the most potential for monitoring antibiotics in real time due to their straightforwardness, high selectivity, and sensitivity. This study highlights novel concepts, insights, and challenges associated with portable devices with potential use as simple paper-based sensors for detecting antibiotics in livestock.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00272"},"PeriodicalIF":11.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-23DOI: 10.1016/j.teac.2025.e00270
Ilya Navitski , Sarunas Zukauskas , Simonas Ramanavicius , Oleksiy Gogotsi , Arunas Ramanavicius
Heavy metals are used across industries worldwide, generating large amounts of waste, leading to environmental contamination. Contamination from heavy metals, such as lead, cadmium, and mercury, causes significant harm to health and quality of life. Thus, the development of new methods to detect heavy metal ions is essential for protecting public health. This can be achieved by creating fast and reliable sensors based on MXenes. The unique properties of MXenes, including tunable surface functionality, excellent electrical conductivity, and remarkable mechanical strength, enhance their suitability in sensor design. This review is focused on the application of MXenes in heavy metal ion sensing, the overview of sensor action mechanisms, and the potential applications of MXene-based sensors in environmental monitoring.
{"title":"2D MXenes in the design of heavy metal ion sensors (review)","authors":"Ilya Navitski , Sarunas Zukauskas , Simonas Ramanavicius , Oleksiy Gogotsi , Arunas Ramanavicius","doi":"10.1016/j.teac.2025.e00270","DOIUrl":"10.1016/j.teac.2025.e00270","url":null,"abstract":"<div><div>Heavy metals are used across industries worldwide, generating large amounts of waste, leading to environmental contamination. Contamination from heavy metals, such as lead, cadmium, and mercury, causes significant harm to health and quality of life. Thus, the development of new methods to detect heavy metal ions is essential for protecting public health. This can be achieved by creating fast and reliable sensors based on MXenes. The unique properties of MXenes, including tunable surface functionality, excellent electrical conductivity, and remarkable mechanical strength, enhance their suitability in sensor design. This review is focused on the application of MXenes in heavy metal ion sensing, the overview of sensor action mechanisms, and the potential applications of MXene-based sensors in environmental monitoring.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00270"},"PeriodicalIF":11.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-21DOI: 10.1016/j.teac.2025.e00271
Miguel Tavares, Simone Morais, Álvaro Torrinha
The widespread presence of pharmaceutical products (PP) in the environment is becoming a global issue, posing a threat to aquatic ecosystems and consequently to human health. This emphasizes the need for effective monitoring tools, such as electrochemical (bio)sensors, comprising advanced (nano)materials to enhance sensitivity and/or selectivity. Particularly, metal-organic frameworks (MOFs) are valuable due to their high porosity, large surface area, and tunable properties. Innovative strategies have been achieved towards MOF-based sensor technology, despite persistent challenges with electron conductivity and water stability. This review discusses the latest developments in MOF-based electrochemical (bio)sensors for detecting PP in the aquatic environment, focusing on the unique attributes of MOFs and strategies to overcome their limitations. Data are described according to the different types of MOFs (ZIF, UiO, MIL, HKUST, other less common), used for detecting 27 different PP. All these studies were published within the last 5 years, highlighting the growing significance of MOFs in sensing applications and the ongoing environmental challenges posed by PP contamination. The reported (bio)sensors proved to be suitable for the sensitive and accurate determination of PP (from fg/L to µg/L) in aquatic ecosystems, with low environmental footprint, especially those based on ZIF-MOF. MOFs are promising materials for the development of (bio)sensors. However, their potential can be fully realized only by moving (bio)sensors beyond the conventional use of traditional transducers and emphasizing advancements in miniaturization, portability, and sustainability. These progresses are essential for positioning MOFs-based electrochemical (bio)sensors as preferred analytical tools in environmental analysis and as viable market solutions.
{"title":"Metal-organic frameworks based electrochemical sensors for emerging pharmaceutical contaminants in the aquatic environment","authors":"Miguel Tavares, Simone Morais, Álvaro Torrinha","doi":"10.1016/j.teac.2025.e00271","DOIUrl":"10.1016/j.teac.2025.e00271","url":null,"abstract":"<div><div>The widespread presence of pharmaceutical products (PP) in the environment is becoming a global issue, posing a threat to aquatic ecosystems and consequently to human health. This emphasizes the need for effective monitoring tools, such as electrochemical (bio)sensors, comprising advanced (nano)materials to enhance sensitivity and/or selectivity. Particularly, metal-organic frameworks (MOFs) are valuable due to their high porosity, large surface area, and tunable properties. Innovative strategies have been achieved towards MOF-based sensor technology, despite persistent challenges with electron conductivity and water stability. This review discusses the latest developments in MOF-based electrochemical (bio)sensors for detecting PP in the aquatic environment, focusing on the unique attributes of MOFs and strategies to overcome their limitations. Data are described according to the different types of MOFs (ZIF, UiO, MIL, HKUST, other less common), used for detecting 27 different PP. All these studies were published within the last 5 years, highlighting the growing significance of MOFs in sensing applications and the ongoing environmental challenges posed by PP contamination. The reported (bio)sensors proved to be suitable for the sensitive and accurate determination of PP (from fg/L to µg/L) in aquatic ecosystems, with low environmental footprint, especially those based on ZIF-MOF. MOFs are promising materials for the development of (bio)sensors. However, their potential can be fully realized only by moving (bio)sensors beyond the conventional use of traditional transducers and emphasizing advancements in miniaturization, portability, and sustainability. These progresses are essential for positioning MOFs-based electrochemical (bio)sensors as preferred analytical tools in environmental analysis and as viable market solutions.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00271"},"PeriodicalIF":11.1,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-22DOI: 10.1016/j.teac.2025.e00269
Hema Sai Buchi Reddy Gari , Shanthi Priya Gaddam , Mohammed Suhaib Al Huq , Nikita J. Patil , Suhail Mubarak , Parthasarathy Srinivasan
The widespread use of organophosphate pesticides, particularly Diazinon, raises significant concerns about environmental contamination and human health due to their high toxicity and potential chemical discharge into water systems. Effective monitoring of Diazinon levels is crucial for minimizing risks associated with agricultural runoff and public safety. Hence, an enormous demand exists for developing highly accurate, rapid, and sensitive Diazinon detection systems. One such rapid and sensitive Diazinon detection system is an electrochemical approach. This review highlights the recent trends and advancements in the electrochemical sensing of Diazinon, along with the critical challenges and future perspectives. The underlying mechanisms in the electrochemical sensing of Diazinon, along with the interactions in the electrode-electrolyte interface, electrode surface modifications with various functional nanomaterials, electron transfer rate reactions, and selectivity of the modified electrodes towards Diazinon have been emphasized. Versatile electrochemical sensors in the context of enzyme-based and enzyme-free sensors, including CNT-enabled sensors, aptasensors, impedimetric sensors, molecularly imprinted polymer sensors and hybrid electrochemical sensors, have been highlighted along with the specific role in the enhancement of electrochemical sensing of Diazinon. This review opens up new insights into elucidating the recent advancements, critical challenges, and strategies in electrochemical probing of Diazinon, which facilitates significant advancements in sensor technology. This review examines current capabilities and future directions and contributes to ongoing environmental protection and public health safety efforts through effective pesticide monitoring strategies.
{"title":"Insights into surface and chemical interactions in electrochemical probing of Diazinon: A comprehensive review on current trends, challenges, and perspectives","authors":"Hema Sai Buchi Reddy Gari , Shanthi Priya Gaddam , Mohammed Suhaib Al Huq , Nikita J. Patil , Suhail Mubarak , Parthasarathy Srinivasan","doi":"10.1016/j.teac.2025.e00269","DOIUrl":"10.1016/j.teac.2025.e00269","url":null,"abstract":"<div><div>The widespread use of organophosphate pesticides, particularly <em>Diazinon</em>, raises significant concerns about environmental contamination and human health due to their high toxicity and potential chemical discharge into water systems. Effective monitoring of <em>Diazinon</em> levels is crucial for minimizing risks associated with agricultural runoff and public safety. Hence, an enormous demand exists for developing highly accurate, rapid, and sensitive <em>Diazinon</em> detection systems. One such rapid and sensitive <em>Diazinon</em> detection system is an electrochemical approach. This review highlights the recent trends and advancements in the electrochemical sensing of <em>Diazinon,</em> along with the critical challenges and future perspectives. The underlying mechanisms in the electrochemical sensing of <em>Diazinon,</em> along with the interactions in the electrode-electrolyte interface, electrode surface modifications with various functional nanomaterials, electron transfer rate reactions, and selectivity of the modified electrodes towards <em>Diazinon</em> have been emphasized. Versatile electrochemical sensors in the context of enzyme-based and enzyme-free sensors, including CNT-enabled sensors, aptasensors, impedimetric sensors, molecularly imprinted polymer sensors and hybrid electrochemical sensors, have been highlighted along with the specific role in the enhancement of electrochemical sensing of <em>Diazinon</em>. This review opens up new insights into elucidating the recent advancements, critical challenges, and strategies in electrochemical probing of <em>Diazinon,</em> which facilitates significant advancements in sensor technology. This review examines current capabilities and future directions and contributes to ongoing environmental protection and public health safety efforts through effective pesticide monitoring strategies.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00269"},"PeriodicalIF":11.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号