Pub Date : 2024-12-04DOI: 10.1016/j.gofs.2024.11.007
Justine Paoli, Rahmeth Radjack
Objectives: Total pregnancy denial is a phenomenon where the woman does not recognize her pregnancy until a late stage, sometimes just before childbirth. These complex situations raise many questions about the support of the mother-child dyad. This qualitative study aims to describe the experiences and strategies of midwives when dealing with cases of total pregnancy denial, as well as the relational dynamics within these particular dyads, in order to identify avenues for appropriate care.
Methodology: Eight semi-structured interviews were conducted with midwives practicing in Île-de-France (hospital, private practice, home hospitalization, and maternal and child protection services). The data were analyzed using grounded theory with the help of the Quirkos software.
Results: The midwives' experiences show that the mother-child relationship evolves favorably in most cases, even in anonymous childbirth situations. The results are organized into several themes: the description of the mother-child relationship, the proposed care approaches, and the midwives' experiences. For the first theme, five sub-themes emerged: maternal investment, psychological ambivalence, childbirth circumstances, the influence of the social environment, and maternal guilt. The second theme highlights the importance of multidisciplinary and personalized support, respecting the pace of the dyad.
Conclusion: This study emphasizes the importance of not stigmatizing women in total pregnancy denial when establishing the mother-child bond. A personalized and gradual care approach, based on empathetic, non-judgmental, and multidisciplinary support, fosters the mother-child bond.
{"title":"[Support for the mother-child relationship during total denial of pregnancy: Midwives' point of view].","authors":"Justine Paoli, Rahmeth Radjack","doi":"10.1016/j.gofs.2024.11.007","DOIUrl":"10.1016/j.gofs.2024.11.007","url":null,"abstract":"<p><strong>Objectives: </strong>Total pregnancy denial is a phenomenon where the woman does not recognize her pregnancy until a late stage, sometimes just before childbirth. These complex situations raise many questions about the support of the mother-child dyad. This qualitative study aims to describe the experiences and strategies of midwives when dealing with cases of total pregnancy denial, as well as the relational dynamics within these particular dyads, in order to identify avenues for appropriate care.</p><p><strong>Methodology: </strong>Eight semi-structured interviews were conducted with midwives practicing in Île-de-France (hospital, private practice, home hospitalization, and maternal and child protection services). The data were analyzed using grounded theory with the help of the Quirkos software.</p><p><strong>Results: </strong>The midwives' experiences show that the mother-child relationship evolves favorably in most cases, even in anonymous childbirth situations. The results are organized into several themes: the description of the mother-child relationship, the proposed care approaches, and the midwives' experiences. For the first theme, five sub-themes emerged: maternal investment, psychological ambivalence, childbirth circumstances, the influence of the social environment, and maternal guilt. The second theme highlights the importance of multidisciplinary and personalized support, respecting the pace of the dyad.</p><p><strong>Conclusion: </strong>This study emphasizes the importance of not stigmatizing women in total pregnancy denial when establishing the mother-child bond. A personalized and gradual care approach, based on empathetic, non-judgmental, and multidisciplinary support, fosters the mother-child bond.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-03DOI: 10.1016/j.gofs.2024.12.001
Maud Vachette, Aude Girault, François Goffinet, Catherine Fischer, Yoann Athiel
Certain obstetric situations, such as abnormalities in placental invasion, present a major hemorrhagic risk often requiring massive transfusion. To reduce complications associated with massive transfusions and minimize the use of the labile blood product stock, perioperative blood salvage techniques, such as the Cell-saver, have been developed, including in obstetrics. The aim of this article is to provide an update on the use of the Cell-saver in obstetrics, particularly during high hemorrhagic risk obstetric surgeries (such as surgeries for placenta accreta). Firstly, we will review the indications for using the Cell-saver in obstetrics and the technical modalities described in the literature and at our expert center. Secondly, in light of the literature data, we will list the benefits associated with the use of the Cell-saver in obstetrics as well as its risks, complications, and contraindications.
{"title":"[High-risk obstetric surgery: Can we do without Cell-saver in France in 2024?]","authors":"Maud Vachette, Aude Girault, François Goffinet, Catherine Fischer, Yoann Athiel","doi":"10.1016/j.gofs.2024.12.001","DOIUrl":"10.1016/j.gofs.2024.12.001","url":null,"abstract":"<p><p>Certain obstetric situations, such as abnormalities in placental invasion, present a major hemorrhagic risk often requiring massive transfusion. To reduce complications associated with massive transfusions and minimize the use of the labile blood product stock, perioperative blood salvage techniques, such as the Cell-saver, have been developed, including in obstetrics. The aim of this article is to provide an update on the use of the Cell-saver in obstetrics, particularly during high hemorrhagic risk obstetric surgeries (such as surgeries for placenta accreta). Firstly, we will review the indications for using the Cell-saver in obstetrics and the technical modalities described in the literature and at our expert center. Secondly, in light of the literature data, we will list the benefits associated with the use of the Cell-saver in obstetrics as well as its risks, complications, and contraindications.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-26DOI: 10.1016/j.gofs.2024.11.005
Estelle Anstett, Philippe Gosset, Loïc Maurer, Jeanine Ohl
Objectives: The new bioethics law of August 2, 2021 allows French women to self-preserve.
Methods: National observational survey over 2 years based on an online questionnaire conducted under the aegis of GEDO (Groupe d'études pour le don d'ovocytes).
Results: The average age of the 282 women who answered the questionnaire, 34.5 years, is consistent with the benefit/risk balance described in the literature. The most educated women, also very vulnerable, remain the most affected. They are single and childless, but most of them see themselves as a couple and want to become mothers in the future. Their main motivation is to have the choice to postpone a pregnancy without fear of infertility until they have found a suitable partner. Careerist or selfish motivations are anecdotal. The projected fate of unused vitrified oocytes is above all donation to others.
Conclusion: This study shows that oocyte self-preservation is undeniably experienced as a societal victory and is perceived as a step towards gender equality. While oocyte self-preservation is not an absolute guarantee of having a future child, it is part of a primary preventive strategy for age-related fertility decline. Public authorities and health professionals will have to widely disseminate accurate and complete information to allow everyone to have access to an informed reproductive choice.
目标:2021年8月2日的新生物伦理法允许法国女性自我保存方法。在GEDO (Groupe d‘Études pour le Don ’ ovocytes)的支持下,通过在线问卷进行了为期2年的全国观察性调查。结果:282名回答问卷的女性的平均年龄为34.5岁,与文献中描述的利益/风险平衡一致。受教育程度最高的妇女,也非常脆弱,仍然是受影响最大的。她们是单身,没有孩子,但她们中的大多数人把自己看作是一对夫妇,并希望在未来成为母亲。她们的主要动机是可以选择推迟怀孕,而不用担心不孕不育,直到找到合适的伴侣。野心家或自私的动机是传闻。未使用的玻璃化卵母细胞的预期命运首先是捐赠给他人。结论:这项研究表明,卵母细胞的自我保存是不可否认的社会胜利,被认为是迈向性别平等的一步。虽然卵母细胞的自我保存并不能绝对保证将来有一个孩子,但它是预防与年龄有关的生育能力下降的主要策略的一部分。公共当局和保健专业人员必须广泛传播准确和完整的信息,使每个人都有机会获得知情的生殖选择。
{"title":"[Profiles and motivations of women seeking oocyte preservation in France: A two-years' survey].","authors":"Estelle Anstett, Philippe Gosset, Loïc Maurer, Jeanine Ohl","doi":"10.1016/j.gofs.2024.11.005","DOIUrl":"10.1016/j.gofs.2024.11.005","url":null,"abstract":"<p><strong>Objectives: </strong>The new bioethics law of August 2, 2021 allows French women to self-preserve.</p><p><strong>Methods: </strong>National observational survey over 2 years based on an online questionnaire conducted under the aegis of GEDO (Groupe d'études pour le don d'ovocytes).</p><p><strong>Results: </strong>The average age of the 282 women who answered the questionnaire, 34.5 years, is consistent with the benefit/risk balance described in the literature. The most educated women, also very vulnerable, remain the most affected. They are single and childless, but most of them see themselves as a couple and want to become mothers in the future. Their main motivation is to have the choice to postpone a pregnancy without fear of infertility until they have found a suitable partner. Careerist or selfish motivations are anecdotal. The projected fate of unused vitrified oocytes is above all donation to others.</p><p><strong>Conclusion: </strong>This study shows that oocyte self-preservation is undeniably experienced as a societal victory and is perceived as a step towards gender equality. While oocyte self-preservation is not an absolute guarantee of having a future child, it is part of a primary preventive strategy for age-related fertility decline. Public authorities and health professionals will have to widely disseminate accurate and complete information to allow everyone to have access to an informed reproductive choice.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-23DOI: 10.1016/j.gofs.2024.11.004
Lina Abdiche, Diane Rivet-Danon, Clémence Farabet-Demarquette, Clarisse Vallée, Anna Ly, Ludmilla Ogouma-Aworet, Marie Prades, Isabelle Berthaut, Kamila Kolanska, Nathalie Sermondade, Charlotte Dupont
Objective: The new bioethics law, enacted on August 2, 2021, has expanded access to medically assisted reproduction (MAR) with sperm donation to unmarried women and female couples. The implementation of this law led to a significant influx of sperm donation requests at French sperm banks. This major development in the field of ART in France, and in French society as a whole, prompted us to focus specifically on the requests from female couples.
Method: A retrospective, single-center study was conducted at a gamete donation center in Paris. The data of women in same-sex couples who attended a first consultation with a biologist between October 1, 2021, and October 31, 2022, were analyzed and compared to those of women in heterosexual couples who also requested MAR with sperm donation during the same period. The ART attempts and their outcomes were analyzed up until May 31, 2024.
Results: A total of 117 women in same-sex couples and 75 women in heterosexual couples were included in the study. The profiles in terms of age, ovarian reserve, and history of gynecological conditions did not differ between the two groups. The only observed differences were related to lifestyle, particularly alcohol consumption, which was slightly higher among women in same-sex couples. Additionally, women in same-sex couples appeared to belong more frequently to the category of intermediate professions, but no differences were observed concerning other occupational categories. Regarding the outcomes of ART attempts, cumulative rates of early and ongoing pregnancies were not different between the two groups.
Conclusion: This study thus provides an initial insight into the profile and outcomes for women in same-sex couples who received ART with sperm donation shortly after the enactment of the bioethics law in France. The similarity in profiles and ART outcomes between women in same-sex couples and those in heterosexual couples supports the approach of offering similar medical care, regardless of the couple's configuration.
{"title":"[First French data on sperm donation requests from female couples].","authors":"Lina Abdiche, Diane Rivet-Danon, Clémence Farabet-Demarquette, Clarisse Vallée, Anna Ly, Ludmilla Ogouma-Aworet, Marie Prades, Isabelle Berthaut, Kamila Kolanska, Nathalie Sermondade, Charlotte Dupont","doi":"10.1016/j.gofs.2024.11.004","DOIUrl":"10.1016/j.gofs.2024.11.004","url":null,"abstract":"<p><strong>Objective: </strong>The new bioethics law, enacted on August 2, 2021, has expanded access to medically assisted reproduction (MAR) with sperm donation to unmarried women and female couples. The implementation of this law led to a significant influx of sperm donation requests at French sperm banks. This major development in the field of ART in France, and in French society as a whole, prompted us to focus specifically on the requests from female couples.</p><p><strong>Method: </strong>A retrospective, single-center study was conducted at a gamete donation center in Paris. The data of women in same-sex couples who attended a first consultation with a biologist between October 1, 2021, and October 31, 2022, were analyzed and compared to those of women in heterosexual couples who also requested MAR with sperm donation during the same period. The ART attempts and their outcomes were analyzed up until May 31, 2024.</p><p><strong>Results: </strong>A total of 117 women in same-sex couples and 75 women in heterosexual couples were included in the study. The profiles in terms of age, ovarian reserve, and history of gynecological conditions did not differ between the two groups. The only observed differences were related to lifestyle, particularly alcohol consumption, which was slightly higher among women in same-sex couples. Additionally, women in same-sex couples appeared to belong more frequently to the category of intermediate professions, but no differences were observed concerning other occupational categories. Regarding the outcomes of ART attempts, cumulative rates of early and ongoing pregnancies were not different between the two groups.</p><p><strong>Conclusion: </strong>This study thus provides an initial insight into the profile and outcomes for women in same-sex couples who received ART with sperm donation shortly after the enactment of the bioethics law in France. The similarity in profiles and ART outcomes between women in same-sex couples and those in heterosexual couples supports the approach of offering similar medical care, regardless of the couple's configuration.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-20DOI: 10.1016/j.gofs.2024.11.003
Hugo Texier, Irène Lacamp, Pierre-François Ceccaldi, Priscille Sauvegrain
Objective: Socio-economic conditions are one of the critical factors of the health of pregnant women. However, precariousness remains poorly defined and detected by general practitioners because too few tools adapted to private practice are available. General practitioners, as the first point of contact for these patients and often the future doctors of the children to come, take charge of them or refer them to other practitioners. Their medical and social practices in this context are mostly undocumented. The purpose of this practice survey is to understand the underlying rationale and frame of reference according to which GPs identify precarious pregnant women and the way they take care of them.
Method: This is a qualitative study based on semi-structured interviews. They were thematically analyzed using the inductive method of grounded theorizing. Private general practitioners carrying out pregnancy follow-ups were enrolled via GP networks and then sampled according to the "respondent driven sampling".
Results: Twelve interviews were conducted between September 2020 and April 2021. The analysis led to explore 6 main themes, poverty identification, feelings about it, the care of precarious women and the attitude, resources and training of the GPs.
Conclusion: The definition of precariousness by GPs is directly linked to their own representation of it. They work in formal or informal networks to avoid being isolated in the care that they describe as complex. They feel the need for suitable training and information related to the support of these patients.
{"title":"[Practices of general practitioners in the follow-up of precarious pregnant patients: A qualitative study].","authors":"Hugo Texier, Irène Lacamp, Pierre-François Ceccaldi, Priscille Sauvegrain","doi":"10.1016/j.gofs.2024.11.003","DOIUrl":"10.1016/j.gofs.2024.11.003","url":null,"abstract":"<p><strong>Objective: </strong>Socio-economic conditions are one of the critical factors of the health of pregnant women. However, precariousness remains poorly defined and detected by general practitioners because too few tools adapted to private practice are available. General practitioners, as the first point of contact for these patients and often the future doctors of the children to come, take charge of them or refer them to other practitioners. Their medical and social practices in this context are mostly undocumented. The purpose of this practice survey is to understand the underlying rationale and frame of reference according to which GPs identify precarious pregnant women and the way they take care of them.</p><p><strong>Method: </strong>This is a qualitative study based on semi-structured interviews. They were thematically analyzed using the inductive method of grounded theorizing. Private general practitioners carrying out pregnancy follow-ups were enrolled via GP networks and then sampled according to the \"respondent driven sampling\".</p><p><strong>Results: </strong>Twelve interviews were conducted between September 2020 and April 2021. The analysis led to explore 6 main themes, poverty identification, feelings about it, the care of precarious women and the attitude, resources and training of the GPs.</p><p><strong>Conclusion: </strong>The definition of precariousness by GPs is directly linked to their own representation of it. They work in formal or informal networks to avoid being isolated in the care that they describe as complex. They feel the need for suitable training and information related to the support of these patients.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-13DOI: 10.1016/j.gofs.2024.11.002
Denis Mukwege, Gautier Chene
{"title":"[Blood and tears. To stop the cycle of conflict-related sexual violence].","authors":"Denis Mukwege, Gautier Chene","doi":"10.1016/j.gofs.2024.11.002","DOIUrl":"10.1016/j.gofs.2024.11.002","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-08DOI: 10.1016/j.gofs.2024.10.010
Caroline Sylvestre, Nathalie Trignol-Viguier
Objective: The law of 7 July 2011 adopts the concept of therapeutic abortion (Medical Termination of Pregnancy or MTP) for maternal reasons if the pregnancy poses a "serious threat" to the woman's health, allowing for the introduction of the concept of psycho-social distress.
Materials and methods: This was a retrospective monocentric study involving 33 women seeking IMG for psychosocial reasons between January 2017 and December 2021 at the University Hospital of Tours. The study resulted in 29 approvals and 25 MTP procedures performed.
Results: Eighty-seven per cent of the requests were accepted. Over half of the women were under 25 years old and were primiparous. The procedures were performed at a mean gestational age of 22 weeks. Sixty percent did not use contraception at the time of conception, and 36% did not use it after the MTP. About a third of the women experienced violence and had psychiatric histories. The majority of the women did not have stable economic resources. Fifty-six per cent of the MTP procedures involved feticide. There were 7 immediate complications with no subsequent consequences. The average time to completion was 16.5 days.
Conclusion: This is a delicate and underexplored subject in literature. Although sporadic in France, these procedures have been practiced for many years. The diversity of opinions during multidisciplinary committees ensures the best objectivity. Requests for psychosocial IMG are rare, but responding to them is in accordance with the law. Analyzing the profile and journey of women has contributed to a better understanding of the complex situations that lead them to this decision.
{"title":"[Study of the profile and trajectory of women seeking a maternal medical termination of pregnancy for psychosocial reasons at the University Hospital of Tours from 2017 to 2021].","authors":"Caroline Sylvestre, Nathalie Trignol-Viguier","doi":"10.1016/j.gofs.2024.10.010","DOIUrl":"10.1016/j.gofs.2024.10.010","url":null,"abstract":"<p><strong>Objective: </strong>The law of 7 July 2011 adopts the concept of therapeutic abortion (Medical Termination of Pregnancy or MTP) for maternal reasons if the pregnancy poses a \"serious threat\" to the woman's health, allowing for the introduction of the concept of psycho-social distress.</p><p><strong>Materials and methods: </strong>This was a retrospective monocentric study involving 33 women seeking IMG for psychosocial reasons between January 2017 and December 2021 at the University Hospital of Tours. The study resulted in 29 approvals and 25 MTP procedures performed.</p><p><strong>Results: </strong>Eighty-seven per cent of the requests were accepted. Over half of the women were under 25 years old and were primiparous. The procedures were performed at a mean gestational age of 22 weeks. Sixty percent did not use contraception at the time of conception, and 36% did not use it after the MTP. About a third of the women experienced violence and had psychiatric histories. The majority of the women did not have stable economic resources. Fifty-six per cent of the MTP procedures involved feticide. There were 7 immediate complications with no subsequent consequences. The average time to completion was 16.5 days.</p><p><strong>Conclusion: </strong>This is a delicate and underexplored subject in literature. Although sporadic in France, these procedures have been practiced for many years. The diversity of opinions during multidisciplinary committees ensures the best objectivity. Requests for psychosocial IMG are rare, but responding to them is in accordance with the law. Analyzing the profile and journey of women has contributed to a better understanding of the complex situations that lead them to this decision.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-06DOI: 10.1016/j.gofs.2024.10.009
Leila Ghassemi, Sébastien Grandfils, Patrick Emonts
{"title":"[Pregnancy in a patient with Turner syndrome after cardiac surgery and double gamete donation].","authors":"Leila Ghassemi, Sébastien Grandfils, Patrick Emonts","doi":"10.1016/j.gofs.2024.10.009","DOIUrl":"10.1016/j.gofs.2024.10.009","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}